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AU2696097A - Advanced glycosylation end-product receptor peptides and uses therefor - Google Patents

Advanced glycosylation end-product receptor peptides and uses therefor

Info

Publication number
AU2696097A
AU2696097A AU26960/97A AU2696097A AU2696097A AU 2696097 A AU2696097 A AU 2696097A AU 26960/97 A AU26960/97 A AU 26960/97A AU 2696097 A AU2696097 A AU 2696097A AU 2696097 A AU2696097 A AU 2696097A
Authority
AU
Australia
Prior art keywords
uses therefor
advanced glycosylation
glycosylation end
receptor peptides
product receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU26960/97A
Inventor
Michael John Morser
Mariko Nagashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU2696097A publication Critical patent/AU2696097A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
AU26960/97A 1996-04-16 1997-04-11 Advanced glycosylation end-product receptor peptides and uses therefor Withdrawn AU2696097A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63314796A 1996-04-16 1996-04-16
US08633147 1996-04-16
PCT/EP1997/001832 WO1997039121A1 (en) 1996-04-16 1997-04-11 Advanced glycosylation end-product receptor peptides and uses therefor

Publications (1)

Publication Number Publication Date
AU2696097A true AU2696097A (en) 1997-11-07

Family

ID=24538464

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26960/97A Withdrawn AU2696097A (en) 1996-04-16 1997-04-11 Advanced glycosylation end-product receptor peptides and uses therefor

Country Status (3)

Country Link
AU (1) AU2696097A (en)
WO (1) WO1997039121A1 (en)
ZA (1) ZA973242B (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6790443B2 (en) 1996-11-22 2004-09-14 The Trustees Of Columbia University In The City Of New York Method for treating symptoms of diabetes
US6555651B2 (en) * 1997-10-09 2003-04-29 The Trustees Of Columbia University In The City Of New York Ligand binding site of rage and uses thereof
US7081241B1 (en) * 1998-10-06 2006-07-25 The Trustees Of Columbia University In The City Of New York Extracellular rage binding protein (EN-RAGE) and uses thereof
US7101838B2 (en) 1997-08-05 2006-09-05 The Trustees Of Columbia University In The City Of New York Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
AU6766800A (en) * 1999-08-13 2001-03-13 Trustees Of Columbia University In The City Of New York, The Methods of inhibiting binding of beta-sheet fibril to rage and consequences thereof
US6908741B1 (en) * 2000-05-30 2005-06-21 Transtech Pharma, Inc. Methods to identify compounds that modulate RAGE
US6613801B2 (en) 2000-05-30 2003-09-02 Transtech Pharma, Inc. Method for the synthesis of compounds of formula I and their uses thereof
EP1724589A3 (en) * 2000-05-30 2007-04-25 TransTech Pharma Inc. Methods to identify compounds that modulate rage
US7919670B1 (en) 2000-08-14 2011-04-05 The Trustees Of Columbia University In The City Of New York Transgenic mice over-expressing receptor for advanced glycation endproduct (RAGE) in brain and uses thereof
US6825164B1 (en) * 2000-08-14 2004-11-30 The Trustees Of Columbia University In The City Of New York Method to increase cerebral blood flow in amyloid angiopathy
AU2002213192A1 (en) 2000-10-13 2002-04-22 The Trustees Of Columbia University In The City Of New York A method for inhibiting new tissue growth in blood vessels in a patient subjected to blood vessel injury
JP2005500254A (en) 2001-03-05 2005-01-06 トランス テック ファーマ,インコーポレイテッド Carboxamide derivatives as therapeutic factors
CA2440037C (en) 2001-03-05 2010-02-16 Transtech Pharma, Inc. Benzimidazole derivatives for modulating the rage receptor
WO2002070667A2 (en) * 2001-03-05 2002-09-12 Transtech Pharma, Inc. High level insect expression of rage proteins
US7754217B2 (en) * 2001-03-16 2010-07-13 Bio3 Research Srl HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases
JP3837494B2 (en) * 2001-03-19 2006-10-25 国立大学法人金沢大学 Soluble RAGE protein
CN100525763C (en) 2002-03-05 2009-08-12 特兰斯泰克制药公司 Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors
WO2005051995A2 (en) * 2003-11-19 2005-06-09 Curagen Corporation Novel advanced glycosylation end product-specific receptor-like protein and nucleic acids encoding same
WO2006012415A2 (en) 2004-07-20 2006-02-02 Critical Therapeutics, Inc. Rage protein derivatives
MX2007001559A (en) 2004-08-03 2007-04-10 Transtech Pharma Inc Rage fusion proteins and methods of use.
CA2581505A1 (en) 2004-09-27 2006-04-06 Centocor, Inc. Srage mimetibody, compositions, methods and uses
US9291621B2 (en) 2005-01-18 2016-03-22 AbbVie Deutschland GmbH & Co. KG AGER-peptides and use thereof
EP1838339A2 (en) * 2005-01-18 2007-10-03 Abbott GmbH & Co. KG Ager-peptides and use thereof
US7981424B2 (en) 2006-05-05 2011-07-19 Transtech Pharma, Inc. RAGE fusion proteins, formulations, and methods of use thereof
PL2158210T3 (en) 2007-06-14 2016-08-31 Galactica Pharmaceuticals Inc Rage fusion proteins
US9034341B2 (en) 2009-04-20 2015-05-19 Transtech Pharma, Llc Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions
JP5805646B2 (en) 2009-09-30 2015-11-04 ブイティーブイ・セラピューティクス・エルエルシー Substituted imidazole derivatives for the treatment of Alzheimer's disease
EP2536283B8 (en) 2010-02-18 2015-11-04 vTv Therapeutics LLC Phenyl-heteroaryl derivatives and methods of use thereof
JP5999542B2 (en) * 2010-11-18 2016-09-28 国立研究開発法人農業・食品産業技術総合研究機構 Method for detecting molecules having ligand-like activity
US9717710B2 (en) 2012-10-05 2017-08-01 Vtv Therapeutics Llc Treatment of mild and moderate Alzheimer's disease
JP6445861B2 (en) * 2014-12-18 2018-12-26 国立大学法人金沢大学 Sample pretreatment method for oxytocin detection
WO2019190822A1 (en) 2018-03-28 2019-10-03 Vtv Therapeutics Llc Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
WO2019190823A1 (en) 2018-03-28 2019-10-03 Vtv Therapeutics Llc Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
JP7464591B2 (en) 2018-10-10 2024-04-09 ブイティーブイ・セラピューティクス・エルエルシー Metabolite of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amine
JP7262102B2 (en) * 2019-02-21 2023-04-21 国立研究開発法人農業・食品産業技術総合研究機構 Assay system for detecting AGEs
JP2021038159A (en) * 2019-09-02 2021-03-11 学校法人慶應義塾 RAGE-derived peptides and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2506792A (en) * 1991-08-23 1993-03-16 Rockefeller University, The Receptors for advanced glycosylation endproducts and uses thereof

Also Published As

Publication number Publication date
WO1997039121A1 (en) 1997-10-23
ZA973242B (en) 1998-08-05

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