AU7146196A - 1,3,5-trisubstituted pyrazoles for treament of inflammation - Google Patents
1,3,5-trisubstituted pyrazoles for treament of inflammationInfo
- Publication number
- AU7146196A AU7146196A AU71461/96A AU7146196A AU7146196A AU 7146196 A AU7146196 A AU 7146196A AU 71461/96 A AU71461/96 A AU 71461/96A AU 7146196 A AU7146196 A AU 7146196A AU 7146196 A AU7146196 A AU 7146196A
- Authority
- AU
- Australia
- Prior art keywords
- treament
- inflammation
- trisubstituted pyrazoles
- trisubstituted
- pyrazoles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- -1 1,3,5-trisubstituted pyrazoles Chemical class 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9520584.5A GB9520584D0 (en) | 1995-10-09 | 1995-10-09 | Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| GB9520584 | 1995-10-09 | ||
| PCT/JP1996/002919 WO1997013755A1 (en) | 1995-10-09 | 1996-10-08 | 1,3,5-trisubstituted pyrazoles for treament of inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU7146196A true AU7146196A (en) | 1997-04-30 |
Family
ID=10782007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU71461/96A Abandoned AU7146196A (en) | 1995-10-09 | 1996-10-08 | 1,3,5-trisubstituted pyrazoles for treament of inflammation |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0856000A1 (en) |
| JP (1) | JPH11513403A (en) |
| KR (1) | KR19990063989A (en) |
| CN (1) | CN1203589A (en) |
| AU (1) | AU7146196A (en) |
| CA (1) | CA2234511A1 (en) |
| GB (1) | GB9520584D0 (en) |
| WO (1) | WO1997013755A1 (en) |
| ZA (1) | ZA968286B (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK138799A3 (en) * | 1997-04-18 | 2001-01-18 | Searle & Co | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
| US5886191A (en) * | 1997-08-18 | 1999-03-23 | Dupont Pharmaceuticals Company | Amidinoindoles, amidinoazoles, and analogs thereof |
| AUPO941497A0 (en) * | 1997-09-24 | 1997-10-16 | Fujisawa Pharmaceutical Co., Ltd. | Novel compounds |
| AUPP042397A0 (en) * | 1997-11-18 | 1997-12-11 | Fujisawa Pharmaceutical Co., Ltd. | 5-arylpyrazole compounds |
| NZ333399A (en) | 1997-12-24 | 2000-05-26 | Sankyo Co | Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis |
| ES2137138B1 (en) * | 1998-05-29 | 2000-09-16 | Esteve Labor Dr | DERIVATIVES OF PIRAZOLINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINES. |
| US6506747B1 (en) * | 1998-06-05 | 2003-01-14 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents |
| US6727238B2 (en) | 1998-06-11 | 2004-04-27 | Pfizer Inc. | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents |
| US6294558B1 (en) | 1999-05-31 | 2001-09-25 | Pfizer Inc. | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents |
| WO2000018741A2 (en) * | 1998-09-30 | 2000-04-06 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazole compounds as cox-2 inhibitors |
| MXPA02002111A (en) * | 1999-08-27 | 2002-10-31 | Abbott Lab | Sulfonylphenylpyrazole compounds useful as cox 2 inhibitors. |
| EP1104758B1 (en) | 1999-12-03 | 2003-07-23 | Pfizer Products Inc. | Acetylene derivatives as anti-inflammatory/analgesic agents |
| DE60001623T2 (en) | 1999-12-03 | 2003-12-18 | Pfizer Products Inc., Groton | Sulfamoyl heteroaryl pyrazole compounds for use as an analgesic / anti-inflammatory agent |
| HK1052701A1 (en) | 1999-12-03 | 2003-09-26 | 辉瑞产品公司 | Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-ammatory/analgesic agents |
| DK1104759T3 (en) | 1999-12-03 | 2004-01-26 | Pfizer Prod Inc | Heteroberlphenylpyrazole compounds as anti-inflammatory / analgesic agents |
| EP1273582B1 (en) | 2001-07-05 | 2005-06-29 | Pfizer Products Inc. | Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents |
| AR038957A1 (en) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | COMBINATION THERAPY FOR CANCER TREATMENT |
| GT200200183A (en) | 2001-09-28 | 2003-05-23 | PROCEDURE TO PREPARE DERIVATIVES OF HETEROCICLOALQUILSULFONIL PIRAZOL | |
| WO2003037336A1 (en) | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | 1-(5-sulfonyl-pyridin-2-yl)-5-(methylidene-cycloalkylmethoxy)-1h-pyrazole-4-carbonitrile derivatives and other compounds as cyclooxygenase inhibitors for the treatment of arthritis, neurodegeneration and colon cancer |
| EP1539679A4 (en) | 2002-06-28 | 2007-07-04 | Nitromed Inc | Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxigenase-2 selective inhibitors, compositions and methods of use |
| EP2196201A3 (en) | 2002-12-13 | 2010-12-08 | Warner-Lambert Company LLC | Combination of an alpha-2-delta ligand with a pdev inhibitor or a muscarinic antagonist to treat lower urinary tract symptoms |
| EP1708718A1 (en) | 2004-01-22 | 2006-10-11 | Pfizer Limited | Triazole derivatives which inhibit vasopressin antagonistic activity |
| ES2257929B1 (en) * | 2004-07-16 | 2007-05-01 | Laboratorios Del Dr. Esteve, S.A. | DERIVATIVES OF PIRAZOLINA, PROCEDURE FOR OBTAINING AND USING THE SAME AS THERAPEUTIC AGENTS. |
| CN102058885B (en) | 2006-12-22 | 2013-04-10 | 瑞蔻达蒂爱尔兰有限公司 | Combination therapy of lower urinary tract diseases with α2δ ligands and NSAIDs |
| BR112015002078A8 (en) * | 2012-07-30 | 2018-03-06 | Univ Ohio State | protein kinase inhibitor manufacturing method |
| WO2022195579A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH27357A (en) * | 1989-09-22 | 1993-06-21 | Fujisawa Pharmaceutical Co | Pyrazole derivatives and pharmaceutical compositions comprising the same |
| IL104311A (en) * | 1992-02-05 | 1997-07-13 | Fujisawa Pharmaceutical Co | Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| CA2276945C (en) * | 1993-11-30 | 2006-08-01 | G.D. Searle & Co. | Tricyclic-substituted pyrazolyl benzenesulfonamides and pharmaceutical compositions thereof |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| US5434178A (en) * | 1993-11-30 | 1995-07-18 | G.D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| WO1996014302A1 (en) * | 1994-11-08 | 1996-05-17 | Eisai Co., Ltd. | Pyrazole derivatives exhibiting anti-inflammatory and analgesic effects |
-
1995
- 1995-10-09 GB GBGB9520584.5A patent/GB9520584D0/en active Pending
-
1996
- 1996-10-02 ZA ZA968286A patent/ZA968286B/en unknown
- 1996-10-08 CN CN96198649A patent/CN1203589A/en active Pending
- 1996-10-08 KR KR1019980702464A patent/KR19990063989A/en not_active Withdrawn
- 1996-10-08 AU AU71461/96A patent/AU7146196A/en not_active Abandoned
- 1996-10-08 EP EP96932841A patent/EP0856000A1/en not_active Withdrawn
- 1996-10-08 JP JP9514909A patent/JPH11513403A/en active Pending
- 1996-10-08 WO PCT/JP1996/002919 patent/WO1997013755A1/en not_active Application Discontinuation
- 1996-10-08 CA CA002234511A patent/CA2234511A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR19990063989A (en) | 1999-07-26 |
| EP0856000A1 (en) | 1998-08-05 |
| GB9520584D0 (en) | 1995-12-13 |
| CA2234511A1 (en) | 1997-04-17 |
| WO1997013755A1 (en) | 1997-04-17 |
| ZA968286B (en) | 1997-05-13 |
| JPH11513403A (en) | 1999-11-16 |
| CN1203589A (en) | 1998-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU7146196A (en) | 1,3,5-trisubstituted pyrazoles for treament of inflammation | |
| AU1088695A (en) | 1,5-diphenyl pyrazole compounds for treatment of inflammation | |
| AU6322696A (en) | Self-healing network | |
| AU697137B2 (en) | Microbicidal triazolyl derivatives | |
| AU3548795A (en) | Benzopyranopyrazolyl derivatives for the treatment of inflammation | |
| AU5482398A (en) | New substituted pyrazole derivatives for the treatment of cardiovascular disorders | |
| AU4493196A (en) | Wound dressing | |
| AU6221396A (en) | Microbicidal (mercapto-triazolyl methyl)-dioxacycloalkanes | |
| AU3917595A (en) | Continuous unloader | |
| AU6525296A (en) | Wound treatment composition | |
| AU2388895A (en) | Substituted cyclopentadienyl compounds for the treatment of inflammation | |
| AU4329396A (en) | Use of 3,4-diphenylchromans | |
| AU5243996A (en) | Orthopedic casting tape | |
| AU4632696A (en) | Pyrazole derivatives and herbicides | |
| AU2424895A (en) | Substituted spirodienes for the treatment of inflammation | |
| AU7579696A (en) | Herbicidal substituted pyrazole compounds | |
| AU6738796A (en) | Microbicidal mercapto-triazolyl-ketones | |
| AU7001496A (en) | Anti-inflammatory agent | |
| AU4633996A (en) | Pyrazole derivatives | |
| AU6673196A (en) | Wound bandage unit | |
| AU7145296A (en) | Pyrazole derivatives | |
| AU4675596A (en) | Azole compounds, their production and use | |
| AU6738896A (en) | Microbicidal mercapto-triazolyl-nitriles | |
| AU5120596A (en) | Pyrazole derivatives | |
| AU7227796A (en) | Pyrazolone derivatives |