AU7700400A - Uroguanylin as an intestinal cancer inhibiting agent - Google Patents

Uroguanylin as an intestinal cancer inhibiting agent

Info

Publication number: AU7700400A
Authority: AU; Australia
Prior art keywords: uroguanylin; inhibiting agent; intestinal cancer; cancer inhibiting; intestinal
Prior art date: 1999-10-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU77004/00A

Inventor

Mark G Currie

Kunwar Shailubhai

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmacia LLC

Original Assignee

Pharmacia LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-06

Filing date

2000-10-04

Publication date

2001-05-10

2000-10-04 Application filed by Pharmacia LLC filed Critical Pharmacia LLC

2001-05-10 Publication of AU7700400A publication Critical patent/AU7700400A/en

Status Abandoned legal-status Critical Current

Links

208000005016 Intestinal Neoplasms Diseases 0.000 title 1
102400000230 Uroguanylin Human genes 0.000 title 1
101800000255 Uroguanylin Proteins 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
201000002313 intestinal cancer Diseases 0.000 title 1
SJMPVWVIVWEWJK-AXEIBBKLSA-N uroguanylin Chemical compound SC[C@@H](C(O)=O)NC(=O)CNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CCC(N)=O SJMPVWVIVWEWJK-AXEIBBKLSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AU77004/00A 1999-10-06 2000-10-04 Uroguanylin as an intestinal cancer inhibiting agent Abandoned AU7700400A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US15795099P	1999-10-06	1999-10-06
US60157950		1999-10-06
PCT/US2000/021998 WO2001025266A1 (en)	1999-10-06	2000-10-04	Uroguanylin as an intestinal cancer inhibiting agent

Publications (1)

Publication Number	Publication Date
AU7700400A true AU7700400A (en)	2001-05-10

Family

ID=22566032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU77004/00A Abandoned AU7700400A (en)	1999-10-06	2000-10-04	Uroguanylin as an intestinal cancer inhibiting agent

Country Status (4)

Country	Link
EP (1)	EP1220872A1 (en)
JP (1)	JP2003516316A (en)
AU (1)	AU7700400A (en)
WO (1)	WO2001025266A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EA006651B1 (en)	2001-03-29	2006-02-24	Синерджи Фармасьютикалз, Инк.	Guanylate cyclase receptor for the treatment of tissue inflammation and carcinogenesis
US7304036B2 (en)	2003-01-28	2007-12-04	Microbia, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
US7371727B2 (en)	2003-01-28	2008-05-13	Microbia, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
CN100589839C (en) *	2003-01-28	2010-02-17	艾恩伍德医药品股份有限公司	Polypeptide and pharmaceutical composition containing the same
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
WO2004071436A2 (en)	2003-02-10	2004-08-26	Thomas Jefferson University	The use of gcc ligands
US7494979B2 (en)	2003-06-13	2009-02-24	Ironwood Pharmaceuticals, Inc.	Method for treating congestive heart failure and other disorders
WO2005016244A2 (en)	2003-06-13	2005-02-24	Microbia, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2688161C (en)	2007-06-04	2020-10-20	Kunwar Shailubhai	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US20100184675A1 (en) *	2007-09-11	2010-07-22	Dorian Bevec	Use of glucagon (1-29) alone or in combination with neuropeptide w30 as a therapeutic agent
EP2810951B1 (en)	2008-06-04	2017-03-15	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2559840T3 (en)	2008-06-04	2016-02-16	Synergy Pharmaceuticals Inc.	Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (en)	2008-07-16	2017-07-17	Synergy Pharmaceuticals Inc.	Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
JP5964589B2 (en)	2008-12-03	2016-08-03	シナジーファーマシューティカルズインコーポレイテッド	Preparation of guanylate cyclase C agonist and method of use thereof
PT2603232T (en)	2010-08-11	2020-01-09	Ironwood Pharmaceuticals Inc	Stable formulations of linaclotide
JP6393037B2 (en)	2010-09-15	2018-09-19	シナジーファーマシューティカルズインコーポレイテッド	Formulation and method of use of guanylate cyclase C agonist
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
US20150086481A1 (en) *	2011-07-28	2015-03-26	Memorial Sloan-Kettering Cancer Center	Diagnosis and treatment of parkinson's disease
US9708367B2 (en)	2013-03-15	2017-07-18	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase and their uses
JP2016514670A (en)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	Guanylate cyclase receptor agonists in combination with other drugs
PL4096784T3 (en) *	2020-01-31	2025-09-08	Sequela, Inc.	BIOMARKER, METHODS AND COMPOSITIONS FOR ASSESSING OR MONITORING RENAL FUNCTION OR DIAGNOSING OR AIDING IN DIAGNOSIS OF ABNORMAL RENAL FUNCTION OR KIDNEY DISEASE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5962220A (en) *	1993-10-26	1999-10-05	Thomas Jefferson University	Compositions that specifically bind to colorectal cells and methods of using the same
US5879656A (en) *	1993-10-26	1999-03-09	Thomas Jefferson University	Methods of treating metastatic colorectal cancer with ST receptor binding compounds
CA2254082C (en) *	1996-05-03	2012-09-11	Thomas Jefferson University	Metastatic colorectal cancer vaccine
WO1999039748A1 (en) *	1998-02-06	1999-08-12	Nycomed Imaging As	Targeting immunoreagents useful in therapeutic and diagnostic compositions and methods

2000
- 2000-10-04 AU AU77004/00A patent/AU7700400A/en not_active Abandoned
- 2000-10-04 WO PCT/US2000/021998 patent/WO2001025266A1/en not_active Application Discontinuation
- 2000-10-04 JP JP2001528206A patent/JP2003516316A/en not_active Withdrawn
- 2000-10-04 EP EP00966698A patent/EP1220872A1/en not_active Withdrawn

Also Published As

Publication number	Publication date
JP2003516316A (en)	2003-05-13
EP1220872A1 (en)	2002-07-10
WO2001025266A1 (en)	2001-04-12

Publication	Publication Date	Title
AU2020501A (en)	2001-06-18	Chemotherapy treatment
AU7700400A (en)	2001-05-10	Uroguanylin as an intestinal cancer inhibiting agent
AU6908500A (en)	2001-04-24	Treatment for narcolepsy
AU5259100A (en)	2000-11-10	Medicament
AU1173201A (en)	2001-05-14	Skin-gripper
AU3092999A (en)	2000-10-04	Digital-timeshare-exchange
AU6599800A (en)	2001-03-05	Endoscope
AU5967600A (en)	2001-02-13	Candystraw
AU7514700A (en)	2001-04-10	Cyanopiperidines
AU2578200A (en)	2001-01-22	Jammer
AU4115400A (en)	2000-11-14	Short-circuiter
AU6335000A (en)	2001-04-24	Depthimeter
AU1554301A (en)	2001-06-12	Radioprotecting agent
AU2023701A (en)	2001-06-18	Sketcher
AU2699800A (en)	2000-09-04	Organoceramics
AU2804600A (en)	2000-09-04	Arylaminoalkylamides
AU7730100A (en)	2001-04-30	Endoscope system
AU6098300A (en)	2001-02-05	Follistatin-3
AU4916900A (en)	2000-12-05	Benzofuranylsulfonates
AU4561600A (en)	2000-12-05	Benzofuranylaminoalcohols
AU5833100A (en)	2001-01-02	Survival jacket
AU7919100A (en)	2001-04-30	Clear hair-treatment agent
AU1901801A (en)	2001-05-30	Glucofuranoses
AU2582200A (en)	2000-09-14	Windturbine
AU7513400A (en)	2001-04-30	Hydantoin-racemase

Legal Events

Date	Code	Title	Description
2002-06-06	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase