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BG107891A - П...п'иди и/или про'...ини и 'яхно'о използван... за пол"-аван... на л...кар''в...но 'р...д''во за л...-...ни... и/или про"илак'ика - Google Patents

П...п'иди и/или про'...ини и 'яхно'о използван... за пол"-аван... на л...кар''в...но 'р...д''во за л...-...ни... и/или про"илак'ика Download PDF

Info

Publication number
BG107891A
BG107891A BG107891A BG10789103A BG107891A BG 107891 A BG107891 A BG 107891A BG 107891 A BG107891 A BG 107891A BG 10789103 A BG10789103 A BG 10789103A BG 107891 A BG107891 A BG 107891A
Authority
BG
Bulgaria
Prior art keywords
peptides
medicament
residue
preparation
apr
Prior art date
Application number
BG107891A
Other languages
Bulgarian (bg)
English (en)
Inventor
Peter Petzelbauer
Original Assignee
Fibrex Medical Research & Development Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrex Medical Research & Development Gmbh filed Critical Fibrex Medical Research & Development Gmbh
Publication of BG107891A publication Critical patent/BG107891A/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/363Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BG107891A 2000-12-12 2003-06-09 П...п'иди и/или про'...ини и 'яхно'о използван... за пол"-аван... на л...кар''в...но 'р...д''во за л...-...ни... и/или про"илак'ика BG107891A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT20632000 2000-12-12
PCT/AT2001/000387 WO2002048180A2 (fr) 2000-12-12 2001-12-07 Peptides et/ou proteines ainsi que leur utilisation dans la fabrication d'un medicament therapeutique et/ou preventif

Publications (1)

Publication Number Publication Date
BG107891A true BG107891A (bg) 2004-08-31

Family

ID=3689750

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107891A BG107891A (bg) 2000-12-12 2003-06-09 П...п'иди и/или про'...ини и 'яхно'о използван... за пол"-аван... на л...кар''в...но 'р...д''во за л...-...ни... и/или про"илак'ика

Country Status (30)

Country Link
US (4) US7271144B2 (fr)
EP (2) EP1586586B1 (fr)
JP (1) JP4181874B2 (fr)
KR (1) KR100864069B1 (fr)
CN (2) CN101676299A (fr)
AT (2) ATE425184T1 (fr)
AU (1) AU2002221316A1 (fr)
BG (1) BG107891A (fr)
BR (1) BR0116122A (fr)
CA (1) CA2430972C (fr)
CY (2) CY1106108T1 (fr)
CZ (1) CZ20031630A3 (fr)
DE (2) DE50110182D1 (fr)
DK (2) DK1586586T3 (fr)
EA (1) EA005576B1 (fr)
EE (1) EE200300283A (fr)
ES (2) ES2323963T3 (fr)
HR (1) HRP20030564A2 (fr)
HU (1) HUP0401536A3 (fr)
IL (2) IL156360A0 (fr)
MX (1) MXPA03005218A (fr)
NO (1) NO330767B1 (fr)
NZ (1) NZ550619A (fr)
PL (2) PL209419B1 (fr)
PT (2) PT1341819E (fr)
SI (2) SI1341819T1 (fr)
SK (1) SK7062003A3 (fr)
WO (1) WO2002048180A2 (fr)
YU (1) YU53803A (fr)
ZA (1) ZA200304545B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1586586B1 (fr) 2000-12-12 2009-03-11 Fibrex Medical Research & Development GmbH Peptide et/ou protéines ainsi que leur utilisation dans la fabrication d'un médicament thérapeutique et/ou préventif
SI1691827T1 (sl) * 2004-06-25 2010-01-29 Fibrex Medical Res & Dev Gmbh Uporaba peptidov, izvedenih iz Bbeta-verige človeškega fibrinogena, za zdravljenje šoka
FR2879604B1 (fr) * 2004-12-22 2010-08-13 Biomerieux Sa Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyarthrite rhumatoide, et leurs utilisations
AT502987A1 (de) * 2005-12-23 2007-07-15 Fibrex Medical Res & Dev Gmbh Pharmazeutische zusammensetzung zur behandlung von hämorrhagischem schock und seinen folgeerscheinungen
DK1987063T3 (da) * 2006-02-23 2010-01-04 Fibrex Medical Res & Dev Gmbh Peptider og peptidderivater, fremstilling deraf samt deres anvendelse til fremstilling af en terapeutisk og/eller præventivt aktiv farmaceutisk sammensætning
WO2007095659A1 (fr) * 2006-02-23 2007-08-30 Fibrex Medical Research & Development Gmbh Peptides et dérivés peptidiques, leur préparation et leur utilisation pour produire un médicament ayant une activité thérapeutique et/ou prophylactique
CN101389653A (zh) 2006-02-23 2009-03-18 菲布雷克斯医疗研究及开发有限责任公司 肽和肽衍生物以及含有它们的药物组合物
FR2900657B1 (fr) * 2006-05-03 2009-04-17 Univ Toulouse Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
US8722623B2 (en) 2007-09-17 2014-05-13 University Of Maryland, Baltimore Compositions and methods utilizing fibrin beta chain fragments
FR2908134B1 (fr) * 2007-12-04 2012-10-12 Univ Toulouse 3 Paul Sabatier Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
JP5410997B2 (ja) * 2008-01-31 2014-02-05 則行 川村 うつ病およびうつ状態のマーカーおよびそれを用いた検出・診断
US20090286725A1 (en) * 2008-05-15 2009-11-19 Fibrex Medical Research & Development Gmbh Peptides and derivatives thereof, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
US8088890B2 (en) * 2008-09-26 2012-01-03 Fibrex Medical Research & Development Gmbh Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
WO2010043444A2 (fr) * 2008-10-15 2010-04-22 Fibrex Medical Research & Development Gmbh Préparation pharmaceutique pour le traitement et/ou la prévention d'une lésion par ischémie/reperfusion et de ses séquelles
US20100152832A1 (en) * 2008-12-12 2010-06-17 Medtronic Vascular, Inc. Apparatus and Methods for Treatment of Aneurysms With Fibrin Derived Peptide B-Beta
WO2013082458A1 (fr) 2011-12-02 2013-06-06 The Regents Of The University Of California Solution de protection de reperfusion et ses utilisations
US12171802B2 (en) 2016-06-02 2024-12-24 University Of Maryland, Baltimore Compositions for inhibiting fibrin-VLDL receptor-dependent inflammation and methods of treatment
EP3912679A1 (fr) * 2020-05-19 2021-11-24 Johann Wolfgang Goethe-Universität Frankfurt am Main Bbeta pour le traitement de l'endothélite virale

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927916A (en) 1984-04-23 1990-05-22 The General Hospital Corporation Method of producing fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity using fibrin-specific peptides
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
DE19729591A1 (de) * 1997-07-10 1999-02-11 Therasorb Medizinische Systeme Mittel zur Behandlung und/oder Prophylaxe von Mikrozirkulationsstörungen
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
EP1586586B1 (fr) * 2000-12-12 2009-03-11 Fibrex Medical Research & Development GmbH Peptide et/ou protéines ainsi que leur utilisation dans la fabrication d'un médicament thérapeutique et/ou préventif
US7201763B2 (en) * 2001-10-24 2007-04-10 Boston Scientific Scimed, Inc. Distal balloon waist material relief and method of manufacture

Also Published As

Publication number Publication date
CA2430972C (fr) 2014-08-05
US20040192596A1 (en) 2004-09-30
US7811985B2 (en) 2010-10-12
PT1586586E (pt) 2010-05-28
ES2266093T3 (es) 2007-03-01
ZA200304545B (en) 2004-09-13
ES2323963T3 (es) 2009-07-28
WO2002048180A3 (fr) 2003-01-30
PL362924A1 (en) 2004-11-02
JP2004527469A (ja) 2004-09-09
MXPA03005218A (es) 2004-12-03
NO20032656L (no) 2003-06-12
IL156360A0 (en) 2004-01-04
BR0116122A (pt) 2003-10-14
SK7062003A3 (en) 2003-11-04
US20090137464A1 (en) 2009-05-28
CN1518558A (zh) 2004-08-04
NO20032656D0 (no) 2003-06-12
US20070037749A1 (en) 2007-02-15
EP1586586B1 (fr) 2009-03-11
NZ550619A (en) 2008-06-30
SI1341819T1 (sl) 2006-10-31
EA200300678A1 (ru) 2003-10-30
PL209752B1 (pl) 2011-10-31
CY1106108T1 (el) 2011-06-08
DK1341819T3 (da) 2006-10-16
ATE329614T1 (de) 2006-07-15
WO2002048180A2 (fr) 2002-06-20
NO330767B1 (no) 2011-07-11
CN1518558B (zh) 2010-06-16
KR100864069B1 (ko) 2008-10-16
EP1586586A2 (fr) 2005-10-19
US20090088384A1 (en) 2009-04-02
US7494973B2 (en) 2009-02-24
HRP20030564A2 (en) 2005-06-30
DK1586586T3 (da) 2009-06-29
EA005576B1 (ru) 2005-04-28
EP1341819B1 (fr) 2006-06-14
US8067373B2 (en) 2011-11-29
CZ20031630A3 (cs) 2003-10-15
HUP0401536A2 (hu) 2004-11-29
HK1084400A1 (zh) 2006-07-28
DE50110182D1 (de) 2006-07-27
PT1341819E (pt) 2006-10-31
DE50114771D1 (de) 2009-04-23
KR20030060988A (ko) 2003-07-16
SI1586586T1 (sl) 2009-08-31
US7271144B2 (en) 2007-09-18
EP1341819A2 (fr) 2003-09-10
CY1109107T1 (el) 2014-07-02
YU53803A (sh) 2006-03-03
CN101676299A (zh) 2010-03-24
AU2002221316A1 (en) 2002-06-24
JP4181874B2 (ja) 2008-11-19
ATE425184T1 (de) 2009-03-15
CA2430972A1 (fr) 2002-06-20
EP1586586A3 (fr) 2006-03-29
IL156360A (en) 2012-12-31
HUP0401536A3 (en) 2008-09-29
EE200300283A (et) 2003-10-15
PL209419B1 (pl) 2011-08-31

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