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BG102744A - Дозирана лекарствена форма на ибупрофен - Google Patents

Дозирана лекарствена форма на ибупрофен

Info

Publication number
BG102744A
BG102744A BG102744A BG10274498A BG102744A BG 102744 A BG102744 A BG 102744A BG 102744 A BG102744 A BG 102744A BG 10274498 A BG10274498 A BG 10274498A BG 102744 A BG102744 A BG 102744A
Authority
BG
Bulgaria
Prior art keywords
dosage form
iburophene
dosage
medicinal product
carrier
Prior art date
Application number
BG102744A
Other languages
English (en)
Other versions
BG64165B1 (bg
Inventor
Ian PRICE
Original Assignee
The Boots Company Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Company Plc filed Critical The Boots Company Plc
Publication of BG102744A publication Critical patent/BG102744A/bg
Publication of BG64165B1 publication Critical patent/BG64165B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Твърдата дозирана лекарствена форма е приложима при лечението на болки и температура. Тя съдържа ибупрофеново производно и носител, включващ компримируем пълнител, комбиниран с дезинтегрираща съставка. Ибупрофеновото производно е 35% тегл. или повече от дозираната форма. Носителят съдържа още алканометален карбонат или бикарбонат в такова количество, че дозиращата форма да има сила на счупване от6,5 до 15 Кр и време на дезинтегриране, по-малко от 10 min.
BG102744A 1996-02-21 1998-09-02 Дозирана лекарствена форма на ибупрофен BG64165B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9603699.1A GB9603699D0 (en) 1996-02-21 1996-02-21 Therapeutic composition
PCT/EP1997/000841 WO1997030699A2 (en) 1996-02-21 1997-02-19 Dosage form of ibuprofen

Publications (2)

Publication Number Publication Date
BG102744A true BG102744A (bg) 1999-05-31
BG64165B1 BG64165B1 (bg) 2004-03-31

Family

ID=10789176

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102744A BG64165B1 (bg) 1996-02-21 1998-09-02 Дозирана лекарствена форма на ибупрофен

Country Status (25)

Country Link
US (1) US20020034540A1 (bg)
EP (1) EP0881899B1 (bg)
JP (2) JP2000507922A (bg)
KR (1) KR19990087084A (bg)
CN (1) CN1215989A (bg)
AT (1) ATE273696T1 (bg)
AU (1) AU722991B2 (bg)
BG (1) BG64165B1 (bg)
CA (1) CA2246344C (bg)
CZ (1) CZ298371B6 (bg)
DE (1) DE69730314T2 (bg)
DK (1) DK0881899T3 (bg)
ES (1) ES2227670T3 (bg)
GB (1) GB9603699D0 (bg)
HU (1) HUP9901454A3 (bg)
IL (1) IL125803A0 (bg)
NO (1) NO983825L (bg)
NZ (1) NZ331416A (bg)
PL (1) PL187383B1 (bg)
PT (1) PT881899E (bg)
RU (1) RU2182000C2 (bg)
SK (1) SK285032B6 (bg)
UA (1) UA55407C2 (bg)
WO (1) WO1997030699A2 (bg)
ZA (1) ZA971446B (bg)

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US6368618B1 (en) 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
NZ508292A (en) * 1999-11-24 2002-08-28 Mcneil Ppc Inc Treatment of migraine symptoms with ibuprofen and salts thereof
KR100523242B1 (ko) * 2000-05-18 2005-10-24 한미약품 주식회사 이부프로펜을 함유하는 정제 조성물
US20030008003A1 (en) * 2001-04-10 2003-01-09 Fahkreddin Jamali Compositions for enhanced absorption of NSAIDs
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
EP1585500B8 (en) * 2002-12-20 2017-07-26 Auritec Pharmaceuticals Coated particles for sustained-release pharmaceutical administration
US20040176234A1 (en) * 2003-03-07 2004-09-09 Baker Hughes Incorporated Method for improving separation operation of centrifuges and associated improved separation designs
US20080020042A1 (en) * 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
UY28583A1 (es) * 2003-10-30 2005-05-31 Roche Consumer Health Ag Forma de presentación del naproxeno sodico
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
ES2624585T3 (es) * 2004-05-28 2017-07-17 Imaginot Pty Ltd. Sistema de suministro de compuesto terapéutico oral
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
CN1976678B (zh) * 2004-06-29 2010-06-02 奈康明丹麦有限责任公司 水不溶性药快速释放药物组合物的制造方法及通过本方法得到的药物组合物
EP1804772B1 (en) * 2004-08-12 2011-10-05 Reckitt Benckiser Healthcare (UK) Limited Granules comprising a non-steroidal anti-inflammatory drug and a sugar alcohol made by melt extrusion
US20070077297A1 (en) * 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
CN101068532B (zh) * 2004-09-30 2012-03-14 斯科尔医药公司 布洛芬改进释放剂型
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
EP1817021A1 (en) * 2004-11-03 2007-08-15 Equitech Corporation Nsaid compositions exhibiting clinical superiority
DK1850834T3 (da) * 2005-02-09 2014-11-10 Boehringer Ingelheim Int Filmovertrykket tablet indeholdende ibufrofen-lysinat
EP1800667A1 (en) 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
BRPI0609448A2 (pt) 2005-03-22 2010-04-06 Losan Pharma Gmbh ibuprofeno solubilizado
CA2622704A1 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
AU2006317530B2 (en) 2005-11-28 2011-09-01 Imaginot Pty Ltd Oral therapeutic compound delivery system
KR101288924B1 (ko) * 2006-08-16 2013-07-24 에스에스 세야쿠 가부시키 가이샤 경구투여용 제제
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio
US8951562B2 (en) * 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20070521L (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
JP5649305B2 (ja) * 2006-12-20 2015-01-07 テバ ウィメンズ ヘルス インコーポレイテッド プロゲスチンを含む口腔内崩壊性固体剤形ならびにその製造方法および使用方法
CA2723409C (en) * 2008-05-09 2016-11-08 Atacama Labs Oy Method and apparatus for dry granulation
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
WO2010011522A1 (en) 2008-07-21 2010-01-28 Albemarle Corporation High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
WO2011001228A1 (en) * 2008-08-14 2011-01-06 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
SG10201509312UA (en) * 2009-06-22 2015-12-30 Wyeth Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
JP5974469B2 (ja) * 2010-12-24 2016-08-23 ライオン株式会社 錠剤の製造方法
CN103102259B (zh) * 2011-12-23 2014-02-26 海南正瑞医药科技开发有限公司 一种布洛芬水合物晶体、及含该水合物晶体的药物组合物及其制备方法
KR101890649B1 (ko) * 2013-07-30 2018-09-28 라이온 가부시키가이샤 정제
EP2845850A1 (en) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP2886107A1 (en) 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
CA2953722C (en) 2014-07-02 2022-09-13 ObsEva SA Crystalline (3z,5s)-5-(hydroxymethyl)-1-[(2'-methyl-1,1'-biphenyl-4-yl)carbonyl]pyrrolidin-3-one o-methyloxime, and methods of using the same
EP2965746B1 (en) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate
WO2017060920A1 (en) * 2015-10-05 2017-04-13 Strides Shasun Limited Pharmaceutical compositions

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US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
US4684666A (en) * 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
AU8320387A (en) * 1986-10-22 1988-05-25 Upjohn Company, The Treatment of gingivitis with ibuprofen or flurbiprofen
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
HU219242B (en) * 1991-05-13 2001-03-28 Boots Co Plc S(+)-ibuprofen sodium salt dihydrate, pharmaceutical composition comprising this compound and process for production of them
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
DK0607467T3 (da) * 1992-12-01 1999-12-13 Spirig Ag Lægemidler, der indeholder S(+)-ibuprofen

Also Published As

Publication number Publication date
AU722991B2 (en) 2000-08-17
CZ298371B6 (cs) 2007-09-12
ATE273696T1 (de) 2004-09-15
HUP9901454A3 (en) 2001-04-28
NO983825L (no) 1998-10-20
DE69730314T2 (de) 2005-08-18
UA55407C2 (uk) 2003-04-15
PT881899E (pt) 2004-12-31
DK0881899T3 (da) 2004-12-20
ZA971446B (en) 1997-11-25
SK285032B6 (sk) 2006-05-04
JP2000507922A (ja) 2000-06-27
NO983825D0 (no) 1998-08-20
NZ331416A (en) 2000-02-28
PL187383B1 (pl) 2004-06-30
PL328465A1 (en) 1999-02-01
EP0881899B1 (en) 2004-08-18
CZ261798A3 (cs) 1998-11-11
KR19990087084A (ko) 1999-12-15
JP2009073847A (ja) 2009-04-09
WO1997030699A2 (en) 1997-08-28
DE69730314D1 (de) 2004-09-23
BG64165B1 (bg) 2004-03-31
RU2182000C2 (ru) 2002-05-10
CA2246344A1 (en) 1997-08-28
GB9603699D0 (en) 1996-04-17
SK114298A3 (en) 1999-01-11
IL125803A0 (en) 1999-04-11
US20020034540A1 (en) 2002-03-21
EP0881899A2 (en) 1998-12-09
CA2246344C (en) 2009-01-20
AU1793797A (en) 1997-09-10
CN1215989A (zh) 1999-05-05
HUP9901454A2 (hu) 1999-08-30
WO1997030699A3 (en) 1997-10-09
ES2227670T3 (es) 2005-04-01

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