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BR112017016897A2 - cepas fúngicas e métodos de uso - Google Patents

cepas fúngicas e métodos de uso

Info

Publication number
BR112017016897A2
BR112017016897A2 BR112017016897A BR112017016897A BR112017016897A2 BR 112017016897 A2 BR112017016897 A2 BR 112017016897A2 BR 112017016897 A BR112017016897 A BR 112017016897A BR 112017016897 A BR112017016897 A BR 112017016897A BR 112017016897 A2 BR112017016897 A2 BR 112017016897A2
Authority
BR
Brazil
Prior art keywords
fungal strains
methods
strains
fungal
enzymes
Prior art date
Application number
BR112017016897A
Other languages
English (en)
Inventor
Virag Aleksandra
A Bodie Elizabeth
A Sweigard James
Ward Michael
NGUYEN Rochelle
Rabinovich Roman
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of BR112017016897A2 publication Critical patent/BR112017016897A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/13—Protein-histidine kinases (2.7.13)
    • C12Y207/13003—Histidine kinase (2.7.13.3)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

trata-se de cepas fúngicas aprimoradas e o uso das mesmas, em que as cepas fúngicas são capazes de produzir um nível alterado de proteínas, enzimas, variantes e outras substâncias de interesse.
BR112017016897A 2015-02-09 2016-02-09 cepas fúngicas e métodos de uso BR112017016897A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113905P 2015-02-09 2015-02-09
US201562173511P 2015-06-10 2015-06-10
PCT/US2016/017113 WO2016130523A1 (en) 2015-02-09 2016-02-09 Fungal strains and methods of use

Publications (1)

Publication Number Publication Date
BR112017016897A2 true BR112017016897A2 (pt) 2018-03-27

Family

ID=55443333

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017016897A BR112017016897A2 (pt) 2015-02-09 2016-02-09 cepas fúngicas e métodos de uso

Country Status (10)

Country Link
US (1) US10907187B2 (pt)
EP (1) EP3256598B1 (pt)
JP (2) JP2018504936A (pt)
KR (2) KR102616331B1 (pt)
CN (1) CN108064267A (pt)
BR (1) BR112017016897A2 (pt)
DK (1) DK3256598T3 (pt)
MX (1) MX2017009937A (pt)
WO (1) WO2016130523A1 (pt)
ZA (1) ZA201705260B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI631215B (zh) * 2017-04-25 2018-08-01 財團法人食品工業發展研究所 果寡糖組成物及其製備方法
CA3061984A1 (en) 2017-06-06 2018-12-13 Zymergen Inc. A htp genomic engineering platform for improving fungal strains
CN107502598A (zh) * 2017-10-19 2017-12-22 蒋文明 一种固定化葡萄糖氧化酶的制备方法
US11976266B2 (en) 2018-04-24 2024-05-07 Danisco Us Inc. Filamentous fungal strains comprising reduced viscosity phenotypes
WO2019236848A1 (en) * 2018-06-06 2019-12-12 Zymergen Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
JP2021532775A (ja) * 2018-07-30 2021-12-02 ダニスコ・ユーエス・インク タンパク質生産性が強化された表現型を含む突然変異及び遺伝子改変糸状菌株並びにそれらの方法
AU2020372776A1 (en) 2019-10-28 2022-04-28 Danisco Us Inc. Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases
KR20220097451A (ko) * 2019-11-08 2022-07-07 다니스코 유에스 인크. 향상된 단백질 생산성 표현형을 포함하는 진균 균주 및 이의 방법
EP4139332A1 (en) 2020-04-22 2023-03-01 Danisco US Inc. Compositions and methods for enhanced protein production in filamentous fungal cells
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
WO2024006888A1 (en) * 2022-06-30 2024-01-04 Ginkgo Bioworks, Inc. Improved host cells
CN119546339A (zh) 2022-07-15 2025-02-28 丹尼斯科美国公司 用于产生单克隆抗体的方法
CN117736878B (zh) * 2023-10-19 2024-05-14 南京林业大学 一种白腐菌菌种及其在降解林木废弃物中的应用
WO2025155900A1 (en) * 2024-01-18 2025-07-24 Ivu Bio, Inc. Genetically engineered fungi having enhanced production of recalcitrant carbon polymers

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0215594B2 (en) 1985-08-29 2003-10-15 Genencor International, Inc. Heterologous polypeptide expressed in filamentous fungi, processes for their preparation, and vectors for their preparation
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
DE69133100T3 (de) 1990-12-10 2015-09-03 Danisco Us Inc. Verbesserte saccharifizierung von zellulose durch klonierung und vervielfältigung des beta-glukosidase genes aus trichoderma reesei
GB9614700D0 (en) 1996-07-12 1996-09-04 Medical Res Council Over-expression of proteins in E.Coli
WO1998044148A1 (en) * 1997-03-28 1998-10-08 Mycotox, Inc. Histidine kinase assay
US6268328B1 (en) 1998-12-18 2001-07-31 Genencor International, Inc. Variant EGIII-like cellulase compositions
US7314712B2 (en) 2001-07-27 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Systems for in vivo site-directed mutagenesis using oligonucleotides
DE60316896T2 (de) * 2002-10-31 2008-07-17 Sumitomo Chemical Co., Ltd. Transformierte Zelle mit erhöhter Sensitivität für Fungizide und ihre Verwendung
JP2013533737A (ja) * 2010-06-03 2013-08-29 ダニスコ・ユーエス・インク 糸状菌宿主株及びｄｎａ構築物並びにその使用方法

Also Published As

Publication number Publication date
EP3256598B1 (en) 2020-10-14
KR20220136484A (ko) 2022-10-07
KR20170109675A (ko) 2017-09-29
US20180037919A1 (en) 2018-02-08
JP2018504936A (ja) 2018-02-22
JP2021040649A (ja) 2021-03-18
ZA201705260B (en) 2018-12-19
CN108064267A (zh) 2018-05-22
KR102616331B1 (ko) 2023-12-21
MX2017009937A (es) 2017-11-28
DK3256598T3 (da) 2021-01-11
EP3256598A1 (en) 2017-12-20
WO2016130523A1 (en) 2016-08-18
US10907187B2 (en) 2021-02-02

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]