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BR9610241A - Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio - Google Patents

Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio

Info

Publication number
BR9610241A
BR9610241A BR9610241A BR9610241A BR9610241A BR 9610241 A BR9610241 A BR 9610241A BR 9610241 A BR9610241 A BR 9610241A BR 9610241 A BR9610241 A BR 9610241A BR 9610241 A BR9610241 A BR 9610241A
Authority
BR
Brazil
Prior art keywords
bioconjugates
processes
image analysis
metal complexes
containing nitrogen
Prior art date
Application number
BR9610241A
Other languages
English (en)
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of BR9610241A publication Critical patent/BR9610241A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR9610241A 1995-08-17 1996-08-16 Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio BR9610241A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US239495P 1995-08-17 1995-08-17
PCT/US1996/013044 WO1997006830A1 (en) 1995-08-17 1996-08-16 Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands

Publications (1)

Publication Number Publication Date
BR9610241A true BR9610241A (pt) 1999-06-29

Family

ID=21700561

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610241A BR9610241A (pt) 1995-08-17 1996-08-16 Processos para análise de imagem de diagnóstico utilizando bioconjgados de complexos de metal de ligandos macrocíclicos contendo nitrogênio

Country Status (8)

Country Link
US (3) US20040057904A1 (pt)
EP (1) EP0846003A1 (pt)
JP (1) JPH11511168A (pt)
AU (1) AU6896796A (pt)
BR (1) BR9610241A (pt)
CA (1) CA2229781A1 (pt)
NO (1) NO980647L (pt)
WO (1) WO1997006830A1 (pt)

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US20040137638A1 (en) 2002-03-04 2004-07-15 Slomczynska Urszula J. Chromatography of metal complexes
EP2312309B1 (en) * 2001-03-02 2017-11-01 Galera Labs, LLC Enzyme mimetic metal complexes
WO2002098431A1 (en) 2001-06-01 2002-12-12 National Jewish Medical And Research Center Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
US7485721B2 (en) 2002-06-07 2009-02-03 Duke University Substituted porphyrins
DK2056675T3 (en) 2006-10-12 2019-04-23 Galera Labs Llc Methods for treating oral mucositis
KR20160036108A (ko) 2008-05-23 2016-04-01 내셔날 쥬이쉬 헬스 알킬화 종으로의 노출과 관련된 상해를 치료하는 방법
WO2009158633A1 (en) * 2008-06-26 2009-12-30 Curators Of The University Of Missouri On Behalf Of The University Of Missouri-Kansas City Drug conjugates
US9149483B2 (en) 2011-09-26 2015-10-06 Galera Labs, Llc Methods for treatment of diseases
SMT202000377T1 (it) 2015-08-11 2020-09-10 Galera Labs Llc Complessi ad anello macrociclico pentaaza che possiedono biodisponibilita' orale
IL300085A (en) 2016-05-03 2023-03-01 Galera Labs Llc Combination therapy for cancer treatment
US11219614B2 (en) 2016-09-01 2022-01-11 Galera Labs, Llc Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound
EA201992431A1 (ru) 2017-10-13 2020-03-13 ГАЛЕРА ЛЭБЗ, ЭлЭлСи Комбинированная иммунотерапия рака с использованием пента-аза-макроциклического кольцевого комплекса

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BR9610240A (pt) * 1995-08-17 1999-06-29 Monsanto Co Métodos de análise de imagem para diagnóstico utilizando complexos de metal de ligantes macrociclicos que contém nitrogênio
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Also Published As

Publication number Publication date
EP0846003A1 (en) 1998-06-10
NO980647L (no) 1998-04-03
CA2229781A1 (en) 1997-02-27
JPH11511168A (ja) 1999-09-28
US7407645B2 (en) 2008-08-05
AU6896796A (en) 1997-03-12
US20090098047A1 (en) 2009-04-16
US20040057904A1 (en) 2004-03-25
WO1997006830A1 (en) 1997-02-27
NO980647D0 (no) 1998-02-16
US20040131550A1 (en) 2004-07-08

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Legal Events

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FA10 Dismissal: dismissal - article 33 of industrial property law