BRPI0812448A2 - Método para aperfeiçoamento de propriedades de proteína - Google Patents
Método para aperfeiçoamento de propriedades de proteínaInfo
- Publication number
- BRPI0812448A2 BRPI0812448A2 BRPI0812448A BRPI0812448A2 BR PI0812448 A2 BRPI0812448 A2 BR PI0812448A2 BR PI0812448 A BRPI0812448 A BR PI0812448A BR PI0812448 A2 BRPI0812448 A2 BR PI0812448A2
- Authority
- BR
- Brazil
- Prior art keywords
- processing method
- property processing
- protein property
- protein
- property
- Prior art date
Links
- 238000003672 processing method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38681—Chemically modified or immobilised enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01001—Alpha-amylase (3.2.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Crystallography & Structural Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93330707P | 2007-06-06 | 2007-06-06 | |
| US93331207P | 2007-06-06 | 2007-06-06 | |
| US93333107P | 2007-06-06 | 2007-06-06 | |
| PCT/US2008/007114 WO2008153935A2 (en) | 2007-06-06 | 2008-06-06 | Methods for improving protein properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0812448A2 true BRPI0812448A2 (pt) | 2014-10-14 |
Family
ID=39820892
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0812448 BRPI0812448A2 (pt) | 2007-06-06 | 2008-06-06 | Método para aperfeiçoamento de propriedades de proteína |
| BRPI0812206 BRPI0812206A2 (pt) | 2007-06-06 | 2008-06-06 | Métodos para melhorar o desempenho de proteínas |
| BRPI0812446 BRPI0812446A2 (pt) | 2007-06-06 | 2008-06-06 | Métodos para aperfeiçoamento de propriedades de proteína múltiplas |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0812206 BRPI0812206A2 (pt) | 2007-06-06 | 2008-06-06 | Métodos para melhorar o desempenho de proteínas |
| BRPI0812446 BRPI0812446A2 (pt) | 2007-06-06 | 2008-06-06 | Métodos para aperfeiçoamento de propriedades de proteína múltiplas |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US9133425B2 (pt) |
| EP (3) | EP2171055B1 (pt) |
| JP (4) | JP5594895B2 (pt) |
| KR (3) | KR20100031669A (pt) |
| CN (3) | CN101802194B (pt) |
| BR (3) | BRPI0812448A2 (pt) |
| CA (3) | CA2690032C (pt) |
| DK (3) | DK2171056T3 (pt) |
| MX (3) | MX2009013084A (pt) |
| RU (1) | RU2553550C2 (pt) |
| WO (3) | WO2008153935A2 (pt) |
Families Citing this family (47)
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|---|---|---|---|---|
| ES2367505T3 (es) * | 1997-10-23 | 2011-11-04 | Danisco Us Inc. | Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes. |
| DE60234523D1 (de) | 2001-05-15 | 2010-01-07 | Novozymes As | Alpha-amylasevariante mit veränderten eigenschaften |
| DK2171056T3 (en) * | 2007-06-06 | 2017-02-06 | Danisco Us Inc | PROCEDURES FOR IMPROVING PROTEIN EFFICIENCY |
| AU2008325249B2 (en) * | 2007-11-05 | 2013-10-10 | Danisco Us Inc. | Alpha-amylase variants with altered properties |
| DK2215202T4 (da) | 2007-11-05 | 2025-01-02 | Danisco Us Inc | VARIANTER AF BACILLUS sp. TS-23 ALPHA-AMYLASE MED ÆNDREDE EGENSKABER |
| DK2235190T3 (en) | 2007-12-13 | 2018-07-23 | Danisco Us Inc | COMPOSITIONS AND PROCEDURES FOR PRODUCING ISOPRENE |
| MX2010008359A (es) * | 2008-02-04 | 2010-08-30 | Danisco Us Inc | Variantes de alfa-amilasa ts23 con propiedades alteradas. |
| WO2009132220A2 (en) | 2008-04-23 | 2009-10-29 | Danisco Us Inc. | Isoprene synthase variants for improved microbial production of isoprene |
| CN102057040A (zh) | 2008-06-06 | 2011-05-11 | 丹尼斯科美国公司 | 具有改良特性的嗜热脂肪土芽孢杆菌α-淀粉酶(AMYS)变体 |
| CA2726357A1 (en) * | 2008-06-06 | 2009-12-10 | Danisco Us Inc. | Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials |
| WO2010036515A1 (en) | 2008-09-25 | 2010-04-01 | Danisco Us Inc. | Alpha-amylase blends and methods for using said blends |
| BRPI1013167A2 (pt) * | 2009-02-27 | 2015-10-06 | Iogen Energy Corp | enzimas celulases resistentes a lignina |
| DK2414514T3 (en) | 2009-04-01 | 2015-08-24 | Danisco Us Inc | FORMATIONS AND PROCEDURES COMPREHENSIVE Alpha- amylase variants WITH CHANGED PROPERTIES |
| CN102656265A (zh) * | 2009-04-23 | 2012-09-05 | 丹尼斯科美国公司 | 异戊二烯合酶的三维结构及其用于产生变体的用途 |
| KR20120062643A (ko) * | 2009-06-03 | 2012-06-14 | 다니스코 유에스 인크. | 향상된 발현, 활성 및/또는 안정성을 갖는 셀룰라아제 변이체, 및 이의 용도 |
| CA2767170A1 (en) * | 2009-07-09 | 2011-01-13 | The Procter & Gamble Company | A catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte |
| EP2459714A1 (en) * | 2009-07-31 | 2012-06-06 | Danisco US Inc. | Proteases with modified pre-pro regions |
| JP5882904B2 (ja) * | 2009-12-09 | 2016-03-09 | ザ プロクター アンド ギャンブルカンパニー | 布地ケア製品及びホームケア製品 |
| BR112012014082B1 (pt) * | 2009-12-09 | 2020-12-15 | Danisco Us Inc | variante de protease isolada e seu método de produção, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante, composição e método para limpeza de um item ou de uma superfície em necessidade de limpeza |
| FI20096371A0 (fi) * | 2009-12-21 | 2009-12-21 | Turun Yliopisto | Mutageneesi menetelmä |
| AR080886A1 (es) * | 2010-04-15 | 2012-05-16 | Danisco Us Inc | Composiciones y metodos que comprenden proteasas variantes |
| US20120067373A1 (en) * | 2010-04-15 | 2012-03-22 | Philip Frank Souter | Automatic Dishwashing Detergent Composition |
| WO2011140316A1 (en) * | 2010-05-06 | 2011-11-10 | The Procter & Gamble Company | Consumer products with protease variants |
| WO2011143632A2 (en) | 2010-05-14 | 2011-11-17 | Codexis, Inc. | Cellobiohydrolase variants |
| SG190043A1 (en) | 2010-10-27 | 2013-06-28 | Danisco Us Inc | Isoprene synthase variants for improved production of isoprene |
| JP6148183B2 (ja) * | 2011-03-17 | 2017-06-21 | ダニスコ・ユーエス・インク | セルラーゼ組成物並びにこれを用いリグノセルロース系バイオマスの発酵性糖質への変換を向上させる方法 |
| EP2702154A4 (en) * | 2011-04-27 | 2015-04-08 | Codexis Inc | VARIANTS OF CELLOBIOHYDROLASE |
| EP2726607B1 (en) | 2011-06-30 | 2018-08-08 | Novozymes A/S | Alpha-amylase variants |
| WO2013028278A1 (en) | 2011-08-23 | 2013-02-28 | Codexis, Inc. | Cellobiohydrolase variants |
| WO2013110766A1 (en) | 2012-01-26 | 2013-08-01 | Novozymes A/S | Use of polypeptides having protease activity in animal feed and detergents |
| JP6067409B2 (ja) * | 2012-04-10 | 2017-01-25 | 花王株式会社 | アルカリプロテアーゼの溶解性向上方法 |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
| US20150132800A1 (en) | 2012-05-21 | 2015-05-14 | Danisco Us Inc. | Trichoderma Hydrophobin Production |
| US20150140165A1 (en) | 2012-06-20 | 2015-05-21 | Novozymes A/S | Use of polypeptides having protease activity in animal feed and detergents |
| MX2015010078A (es) | 2013-02-06 | 2016-01-25 | Novozymes As | Uso de polipeptidos con actividad proteasa en alimentos para animales. |
| US20160108388A1 (en) | 2013-05-29 | 2016-04-21 | Danisco Us Inc. | Novel metalloproteases |
| EP3786269A1 (en) * | 2013-06-06 | 2021-03-03 | Novozymes A/S | Alpha-amylase variants and polynucleotides encoding same |
| WO2016201040A1 (en) | 2015-06-09 | 2016-12-15 | Danisco Us Inc. | Water-triggered enzyme suspension |
| TWI571472B (zh) * | 2015-11-02 | 2017-02-21 | 基酵生物科技股份有限公司 | 具耐熱性之果膠裂解酶 |
| JP7152319B2 (ja) * | 2016-06-17 | 2022-10-12 | ダニスコ・ユーエス・インク | プロテアーゼ変異体およびその使用 |
| US20200354708A1 (en) * | 2017-11-29 | 2020-11-12 | Danisco Us Inc. | Subtilisin variants having improved stability |
| CN108707595B (zh) * | 2018-07-03 | 2021-07-27 | 华东理工大学 | 一种提高真菌产纤维素酶产量的方法 |
| US20220415431A1 (en) * | 2019-12-19 | 2022-12-29 | Dsm Ip Assets B.V. | Method and system for prediction of a performance of a strain in a plant |
| CN113284562B (zh) * | 2021-06-07 | 2021-12-24 | 中国农业科学院农业基因组研究所 | 一种酶的改良方法 |
| CN114295902B (zh) * | 2021-12-30 | 2024-03-08 | 陕西科技大学 | 一种测定木质素纤维表面电荷密度的方法 |
| AU2023272468A1 (en) | 2022-05-14 | 2024-11-14 | Novonesis Plant Biosolutions A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
| CN117352043B (zh) * | 2023-12-06 | 2024-03-05 | 江苏正大天创生物工程有限公司 | 基于神经网络的蛋白设计方法及系统 |
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