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CA2386889A1 - Methodes de traitement de la chute des cheveux comprenant l'administration d'un compose d'indoline - Google Patents

Methodes de traitement de la chute des cheveux comprenant l'administration d'un compose d'indoline Download PDF

Info

Publication number
CA2386889A1
CA2386889A1 CA002386889A CA2386889A CA2386889A1 CA 2386889 A1 CA2386889 A1 CA 2386889A1 CA 002386889 A CA002386889 A CA 002386889A CA 2386889 A CA2386889 A CA 2386889A CA 2386889 A1 CA2386889 A1 CA 2386889A1
Authority
CA
Canada
Prior art keywords
carbon atoms
alkyl
group
chloro
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002386889A
Other languages
English (en)
Inventor
Karen Marie Lammers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UT Southwestern Medical Center
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2386889A1 publication Critical patent/CA2386889A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne des méthodes de traitement de la chute des cheveux chez des mammifères, incluant l'arrêt de la chute des cheveux, l'inversion du processus de chute des cheveux et/ou l'activation de la croissance des cheveux. Les procédés comprennent l'administration d'une composition contenant un composé d'indoline représenté par la structure (A) ou (I), ou un sel, un hydrate, un tautomère, un amide biohydrolyzable ou un ester pharmaceutiquement acceptables de ce composé. X, Y, R, et R¿1? sont définis dans la description.
CA002386889A 1999-10-26 2000-10-20 Methodes de traitement de la chute des cheveux comprenant l'administration d'un compose d'indoline Abandoned CA2386889A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16157799P 1999-10-26 1999-10-26
US60/161,577 1999-10-26
PCT/US2000/041383 WO2001030151A1 (fr) 1999-10-26 2000-10-20 Methodes de traitement de la chute des cheveux comprenant l'administration d'un compose d'indoline

Publications (1)

Publication Number Publication Date
CA2386889A1 true CA2386889A1 (fr) 2001-05-03

Family

ID=22581774

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002386889A Abandoned CA2386889A1 (fr) 1999-10-26 2000-10-20 Methodes de traitement de la chute des cheveux comprenant l'administration d'un compose d'indoline

Country Status (6)

Country Link
EP (1) EP1223809A4 (fr)
JP (1) JP2003512396A (fr)
AU (1) AU2119001A (fr)
CA (1) CA2386889A1 (fr)
MX (1) MXPA02004010A (fr)
WO (1) WO2001030151A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030187026A1 (en) 2001-12-13 2003-10-02 Qun Li Kinase inhibitors
US6797825B2 (en) 2001-12-13 2004-09-28 Abbott Laboratories Protein kinase inhibitors
JP2006306791A (ja) * 2005-04-28 2006-11-09 Kanebo Cosmetics Inc 養毛剤
KR101857408B1 (ko) * 2018-02-28 2018-05-14 경북대학교 산학협력단 탈모 예방 또는 치료용 조성물
CA3204921A1 (fr) * 2020-12-11 2022-06-16 Elise A. Olsen Compositions et procedes destines a inhiber la croissance pileuse

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
RO109195B1 (ro) * 1988-10-18 1994-12-30 Pfizer Derivati de 3-acil-2-oxindol-1-carboxamide
FR2711060B1 (fr) * 1993-10-13 1995-11-17 Oreal Procédé pour modifier la pousse des poils et/ou des cheveux et compositions utilisables à cet effet.
US5545656A (en) * 1995-04-05 1996-08-13 Pfizer Inc. 2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease
US5859042A (en) * 1995-09-27 1999-01-12 Ono Pharmaceutical Co., Ltd. Five membered heterocyclic compounds

Also Published As

Publication number Publication date
AU2119001A (en) 2001-05-08
EP1223809A1 (fr) 2002-07-24
EP1223809A4 (fr) 2004-03-03
WO2001030151A1 (fr) 2001-05-03
MXPA02004010A (es) 2002-10-23
JP2003512396A (ja) 2003-04-02

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Legal Events

Date Code Title Description
FZDE Dead