CA2437383A1 - Alteration d'un phenotype provoquee par des genes heterologues - Google Patents
Alteration d'un phenotype provoquee par des genes heterologues Download PDFInfo
- Publication number
- CA2437383A1 CA2437383A1 CA002437383A CA2437383A CA2437383A1 CA 2437383 A1 CA2437383 A1 CA 2437383A1 CA 002437383 A CA002437383 A CA 002437383A CA 2437383 A CA2437383 A CA 2437383A CA 2437383 A1 CA2437383 A1 CA 2437383A1
- Authority
- CA
- Canada
- Prior art keywords
- host cell
- target protein
- heterologous target
- protein
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Le phénotype d'une séquence cible d'une cellule hôte pouvant être ciblé peut être altéré par fusion de la protéine cible en un partenaire de fusion approprié.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26609601P | 2001-02-02 | 2001-02-02 | |
| US60/266,096 | 2001-02-02 | ||
| PCT/US2002/002857 WO2002063029A1 (fr) | 2001-02-02 | 2002-02-01 | Alteration d'un phenotype provoquee par des genes heterologues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2437383A1 true CA2437383A1 (fr) | 2002-08-15 |
Family
ID=23013162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002437383A Abandoned CA2437383A1 (fr) | 2001-02-02 | 2002-02-01 | Alteration d'un phenotype provoquee par des genes heterologues |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA2437383A1 (fr) |
| WO (1) | WO2002063029A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10258885A1 (de) * | 2002-12-17 | 2004-07-15 | Aventis Pharma Deutschland Gmbh | Verfahren zur Generierung eines gentechnisch veränderten Organismus |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3377529B2 (ja) * | 1993-09-17 | 2003-02-17 | スミスクライン・ビーチャム・コーポレイション | 薬物結合タンパク質 |
| US7101681B1 (en) * | 1997-11-21 | 2006-09-05 | Amgen, Inc. | Nuclear hormone receptor drug screens |
| EP1053358A4 (fr) * | 1998-02-10 | 2002-08-14 | Uab Research Foundation | Utilisation de l'integrase du vih-1 dans le criblage de medicaments candidats diriges contre le vih-1 |
| CA2378549A1 (fr) * | 1999-07-10 | 2001-01-18 | Calgene Llc | Amelioration de l'expression de proteines |
-
2002
- 2002-02-01 WO PCT/US2002/002857 patent/WO2002063029A1/fr not_active Application Discontinuation
- 2002-02-01 CA CA002437383A patent/CA2437383A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002063029A1 (fr) | 2002-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |