CN104126585B - A kind of combination sterilization composition of fluorine-containing azoles bacterium aniline - Google Patents
A kind of combination sterilization composition of fluorine-containing azoles bacterium aniline Download PDFInfo
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- CN104126585B CN104126585B CN201310166649.6A CN201310166649A CN104126585B CN 104126585 B CN104126585 B CN 104126585B CN 201310166649 A CN201310166649 A CN 201310166649A CN 104126585 B CN104126585 B CN 104126585B
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- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 title claims abstract description 150
- 241000894006 Bacteria Species 0.000 title claims abstract description 77
- 239000000203 mixture Substances 0.000 title claims abstract description 36
- 229910052731 fluorine Inorganic materials 0.000 title claims abstract description 16
- 239000011737 fluorine Substances 0.000 title claims abstract description 16
- 230000001954 sterilising effect Effects 0.000 title claims abstract description 12
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 12
- 150000003851 azoles Chemical class 0.000 title claims abstract description 11
- 125000001153 fluoro group Chemical group F* 0.000 title claims abstract description 8
- WHDHEVMINMZADQ-UHFFFAOYSA-N [F].N1C=CC=C1 Chemical class [F].N1C=CC=C1 WHDHEVMINMZADQ-UHFFFAOYSA-N 0.000 claims abstract description 59
- 239000000470 constituent Substances 0.000 claims abstract description 50
- 201000010099 disease Diseases 0.000 claims abstract description 50
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 50
- 229930182764 Polyoxin Natural products 0.000 claims abstract description 17
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- 235000007164 Oryza sativa Nutrition 0.000 claims description 19
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- 241000221785 Erysiphales Species 0.000 claims description 13
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- 239000004562 water dispersible granule Substances 0.000 claims description 6
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 5
- 241001530056 Athelia rolfsii Species 0.000 claims description 4
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- 239000000843 powder Substances 0.000 claims description 3
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- 239000000575 pesticide Substances 0.000 abstract description 31
- 230000002195 synergetic effect Effects 0.000 abstract description 25
- 150000001875 compounds Chemical class 0.000 abstract description 10
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- 238000013329 compounding Methods 0.000 description 26
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- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 8
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- 238000002474 experimental method Methods 0.000 description 8
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- 229910021641 deionized water Inorganic materials 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- -1 soluble granula Substances 0.000 description 7
- 239000004563 wettable powder Substances 0.000 description 7
- 239000000080 wetting agent Substances 0.000 description 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
- 239000003995 emulsifying agent Substances 0.000 description 6
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 5
- 229940079593 drug Drugs 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
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- 230000001018 virulence Effects 0.000 description 3
- 241000219112 Cucumis Species 0.000 description 2
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 2
- 206010011732 Cyst Diseases 0.000 description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 2
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 208000031513 cyst Diseases 0.000 description 2
- 238000002242 deionisation method Methods 0.000 description 2
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- NDDVRXSINJWQDX-UHFFFAOYSA-N 1,2,2,3,3,4-hexafluoropyrrole Chemical class FC=1C(C(N(C=1)F)(F)F)(F)F NDDVRXSINJWQDX-UHFFFAOYSA-N 0.000 description 1
- GOFJDXZZHFNFLV-UHFFFAOYSA-N 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide Chemical compound CC(C)CC(C)C1=CC=CC=C1NC(=O)C1=C(F)N(C)N=C1C GOFJDXZZHFNFLV-UHFFFAOYSA-N 0.000 description 1
- 229930182536 Antimycin Natural products 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000005815 Penflufen Substances 0.000 description 1
- 241001361634 Rhizoctonia Species 0.000 description 1
- 241000813090 Rhizoctonia solani Species 0.000 description 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
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- CQIUKKVOEOPUDV-IYSWYEEDSA-N antimycin Chemical compound OC1=C(C(O)=O)C(=O)C(C)=C2[C@H](C)[C@@H](C)OC=C21 CQIUKKVOEOPUDV-IYSWYEEDSA-N 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of combination sterilization composition of fluorine-containing azoles bacterium aniline, active ingredient is active components A and the bactericidal composition of active constituent B, and wherein active components A is selected from fluorine azoles bacterium aniline, and active constituent B is selected from any one following compound：Kasugarnycin, jinggangmeisu, polyoxin, antibiotic in pyrimidine nucleoside class, and active components A and the weight ratio of active constituent B are 1 ︰, 80~80 ︰ 1.The present composition has synergistic effect to the multiple diseases for endangering agricultural production, reduces pesticide usage amount, reduces residual quantity of the pesticide on crop, alleviate environmental pollution, to safety of human and livestock, Environmental compatibility is good, and disease is not likely to produce drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, are related to a kind of combination sterilization composition of fluorine-containing azoles bacterium aniline in crop disease
Application in evil.
Background technology
Fluorine azoles bacterium aniline（penflufen）：Molecular formula is C18H24FN3O, chemical name are 2 ＇-[(RS) -1,3- dimethyl
Butyl] fluoro- 1, the 3- dimethyl pyrazoles -4- formailides of -5-, fluorine azoles bacterium aniline is a kind of succinate dehydrogenase inhibitors, mainly
Respiratory chain electron transmission Complex II is acted on, blocks energetic supersession.Kind of a biography can be prevented, the basidiomycetes and ascomycosis that soil passes
Evil, black scurf of potato, wheat sharp eyespot, rice sheath blight disease, sclerotinia sclerotiorum etc., also wheat caused by mainly having rhizoctonia
Smut, the bunt of wheat, corn southern leaf blight etc..Treated, and seed can absorb fluorine azoles bacterium benzene in germination process
Amine is transmitted to other positions of plant by xylem, plays the role of cover crop.
Kasugarnycin, jinggangmeisu, polyoxin, antibiotic in pyrimidine nucleoside class belong to common fungicide, extensive use
In the disease of crops, since antibiotic in pyrimidine nucleoside class is referred to as pesticide corrosion 120, pyrimidine core is substituted with pesticide corrosion 120 below
Glycoside antibiotic.
However, in the real process of agricultural production, controlling disease is easiest to generate the problem that the production of disease drug resistance
It is raw.Different cultivars ingredient is compounded, and is to prevent the very common method of resistance disease.Heterogeneity is compounded, according to reality
Application effect, to judge that certain compounding is synergy, adduction or antagonism.In most cases, the compounding effect of sterilization
All it is additive effect, the compounding for really having synergistic effect is seldom, and especially synergistic effect is clearly, synergy ratio is very high answers
With just less.It is studied by inventor, finds to resist fluorine azoles bacterium aniline with kasugarnycin, jinggangmeisu, polyoxin, agriculture
Can generate good synergistic effect after 120 compoundings, and about fluorine azoles bacterium aniline and kasugarnycin, jinggangmeisu, polyoxin,
The relevant report of pesticide corrosion 120 compounding not yet discloses.
Invention content
There is synergistic function, the fluorine-containing azoles bacterium benzene that use cost is low, preventive effect is good the purpose of the present invention is to propose to a kind of
The combination sterilization composition of amine.
The combination sterilization composition active ingredient of fluorine-containing azoles bacterium aniline proposed by the present invention is active components A and active constituent
B, it is 1 ︰, 80~80 ︰ 1 that activity, which is divided into A and active constituent B weight ratios, and the active components A is selected from fluorine azoles bacterium aniline, activity into
B is divided to be selected from one of kasugarnycin, jinggangmeisu, polyoxin, pesticide corrosion 120 kind, active components A and active constituent B preferred
Weight ratio is 1 ︰, 50~50 ︰ 1；More preferably the weight ratio of fluorine azoles bacterium aniline and kasugarnycin be 1 ︰, 20~25 ︰ 1, fluorine azoles bacterium benzene
Amine is 1 ︰, 25~25 ︰ 1 with jinggangmeisu or the weight ratio of polyoxin or pesticide corrosion 120；Most preferably fluorine azoles bacterium aniline and spring thunder
The weight ratio of mycin is 1 ︰, 4~11 ︰ 1, and the weight ratio of fluorine azoles bacterium aniline and jinggangmeisu or polyoxin is 1 ︰, 9~4 ︰ 1, fluorine azoles
The weight ratio of bacterium aniline and pesticide corrosion 120 is 1 ︰, 4~4 ︰ 1.
The combination sterilization composition of fluorine-containing azoles bacterium aniline proposed by the present invention is used to prevent the purposes of disease on crops, institute
The crops stated include cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit
Crop, hobby crop, root crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop；Institute
The disease stated includes banded sclerotial blight, sclerotiniose, smut, powdery mildew, rust, downy mildew, epidemic disease, gray mold, brown spot, vertical withered
Disease, droop, ring spot, rice blast, anthracnose, angular leaf spot, false smut or bakanae disease.
Active components A, the weight ratio of active constituent B are 1 ︰, 80~80 ︰ 1.The weight hundred of active component in usual composition
Point content is the 0.5%~90% of total weight, preferably 5%~80%.According to different preparation types, active component content range
It is different.In general, liquid preparation contains by weight 1%~70% active material, preferably 5%~50%；Solid pharmaceutical preparation
Contain by weight 5%~80% active material, preferably 10%~80%.
At least containing a kind of surfactant in the bactericidal composition of the present invention, so that active component is in water during application
Dispersion.Surface-active contents are the 5%~30% of total formulation weight, and surplus is solid or liquid diluent.
The bactericidal composition of the present invention can be used through dilution or directly before use by user.Its preparation can be by usual
Processing method known in those skilled in the art prepare, i.e., after active material is mixed with liquid flux or solid carrier,
Add surfactant such as one or more of dispersant, wetting agent, binding agent, antifoaming agent, disintegrant, antifreeze etc..
The bactericidal composition of the present invention, can be processed into acceptable dosage form in any sterilization, wherein more preferably on demand
Dosage form for wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion or microcapsule suspending agent, water can also be made
Agent, soluble powder, soluble granula, suspension emulsion or microcapsule suspension-suspendinagent agent.
Comprising following constituent content when wettable powder is made in composition：Active components A 0.1%~80%, active constituent
B0.1%~80%, dispersant 2%~10%, wetting agent 2%~10%, filler surplus.
Composition includes following constituent content when water dispersible granules are made：Active components A 0.1%~80%, active constituent
B0.1%~80%, dispersant 3%~12%, wetting agent 1%~8%, disintegrant 1%~10%, binding agent 0~8%, filler surplus.
Composition includes following constituent content when suspending agent is made：Active components A 0.1%~50%, active constituent B0.1%~
50%th, dispersant 2%~10%, wetting agent 2%~10%, antifoaming agent 0.01%~2%, thickener 0~2%, antifreeze 0~8%, go from
Sub- water adds to 100%.
Comprising following constituent content when aqueous emulsion is made in composition：Active components A 0.1%~50%, active constituent B0.1%~
50%th, solvent 1%~30%, emulsifier 1%~15%, antifreeze 0~8%, thickener 0~2%, antifoaming agent 0.01%~2%, deionization
Water supplies surplus.
Comprising following constituent content when microemulsion is made in composition：Active components A 0.1%~50%, active constituent B0.1%~
50%th, solvent 1%~30%, emulsifier 3%~25%, antifreeze 0~8%, antifoaming agent 0.01%~2%, deionized water supply surplus.
Composition includes following constituent content when microcapsule suspending agent is made：Active components A 0.1%~50%, active constituent
B0.1%~50%, macromolecule cyst material 2%~10%, dispersant 1%~10%, organic solvent 1%~10%, emulsifier 1%~7%,
Antifoaming agent 0.01%~2%, pH adjusting agent 0.01%~5%, deionized water add to 100%.
The wettable powder the key technical indexes of the present invention：
The water dispersible granules the key technical indexes of the present invention：
The suspending agent the key technical indexes of the present invention：
The aqueous emulsion the key technical indexes of the present invention：
The microemulsion the key technical indexes of the present invention：
The microcapsule suspending agent the key technical indexes of the present invention：
The advantage of the invention is that：
（1）Fluorine azoles bacterium aniline is with after kasugarnycin, jinggangmeisu, polyoxin, pesticide corrosion 120 compounding, having apparent increase
Effect and lasting effect；（2）To cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, do
Orchard crop, hobby crop, root crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop
On disease have greater activity；（3）Reduce pesticide usage amount, reduce residual quantity of the pesticide on crop, alleviate ring
It pollutes in border；（4）To safety of human and livestock, Environmental compatibility is good；And preparation adhesion strength enhances, resistance of rainwater washing against.
Specific embodiment
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The present invention is not limited thereto.
Application Example one
1~16 wettable powder of embodiment
Fluorine azoles bacterium aniline, active constituent B, dispersant, wetting agent, filler are uniformly mixed in mixed cylinder, through air-flow powder
Broken machine remixes uniformly after crushing, you can wettable powder product of the present invention is made, is specifically shown in Table 1.
1 embodiment of table, 1~16 each component and parts by weight
17~26 water dispersible granules of embodiment
Fluorine azoles bacterium aniline, active constituent B, dispersant, wetting agent, disintegrant, filler etc. are obtained together through air-flow crushing
The grain size needed, adds binding agent（Can add can be not added with）Etc. other auxiliary agents, granulation materials are obtained.Item is quantified into feeding fluidisation
In bed granulating drier after granulation and drying, you can water dispersible granules product of the present invention is made, is specifically shown in Table 2.
2 embodiment of table, 17~26 each component and parts by weight
27~36 suspending agent of embodiment
By dispersant, wetting agent, antifoaming agent, thickener（Can add can be not added with）, antifreeze（Can add can be not added with）, by a high speed
Shear-mixed is uniform, adds in fluorine azoles bacterium aniline, active constituent B, ball milling 2~3 hours, make diameter of particle all exist in the ball mill
5 μm hereinafter, surplus is supplied with deionized water, you can suspending agent product of the present invention is made, is specifically shown in Table 3.
3 embodiment of table, 27~36 each component and parts by weight
37~46 aqueous emulsion of embodiment
Fluorine azoles bacterium aniline, active constituent B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；By deionization
Water, antifreeze（Can add can be not added with）, thickener（Can add can be not added with）, antifoaming agent mix, into uniform water phase.In high-speed stirring
It mixes down, water phase is added in into oil phase, surplus is supplied with deionized water；Aqueous emulsion product of the present invention is can be prepared by, is specifically shown in
Table 4.
4 embodiment of table, 37~46 each component and parts by weight
Kasugarnycin, jinggangmeisu, polyoxin, pesticide corrosion 120 in table 1~4 are exchanged, novel formulation can be made.
47~49 microemulsion of embodiment
By fluorine azoles bacterium aniline, active constituent B, solvent, emulsifier, antifreeze（Can add can be not added with）, antifoaming agent is sufficiently mixed
Into the oil phase of homogeneous transparent, it is slowly added into deionized water under stiring, forms WO emulsion, then agitated heating, makes
Rapid phase inversion into oil-in-water type, be cooled to room temperature and make up to balance, filtered, surplus is supplied with deionized water；It can be prepared by
Microemulsion product of the present invention, is specifically shown in Table 5.
5 embodiment of table, 47~49 each component and parts by weight
Embodiment 50,51 microcapsule suspending agents
Fluorine azoles bacterium aniline, active constituent B, macromolecule cyst material, solvent are mixed, makes to be dissolved into homogeneous oil phase, cut
Under tangent condition, by oil phase be added to containing emulsifier, pH adjusting agent, dispersant aqueous phase solution in, surplus is mended with deionized water
Foot, two kinds of materials react in oil-water interfaces, form high score ascus wall, the well dispersed micro-capsule of the present composition is made and hangs
Floating agent product.Specifically it is shown in Table 6.
6 embodiment 50 of table, 51 each components and parts by weight
The embodiment of the present invention is the method being combined using Toxicity Determination and field trial.First pass through indoor virulence survey
Calmly, the synergy ratio after clear and definite two kinds of medicaments compound by a certain percentage（SR）, SR ＜ 0.5 be antagonism, 0.5≤SR≤1.5
For summation action, SR ＞ 1.5 are synergistic effect, on this basis, then carry out field trial.
Test method：After prerun determines the effective inhibition concentration range of each medicament, medicament sets 5 respectively by active constituent content
A dosage processing, if clear water compares.Reference《Farm-chemical indoor determination test rule fungicide》It carries out, speed is grown using mycelia
Rate method measures virulence of the medicament to crop germ.Colony diameter is measured with crossing method after 72h, calculates the net growth of each processing
Amount, mycelial growth inhibition rate.
Net growth（mm）=measurement colony diameter -5
Mycelial growth inhibition rate is converted into probit value（y）, liquor strength（μg/mL）It is converted into logarithm（x）, with minimum
Square law acquires virulence regression equation（y=a+bx）, and thus calculate the EC of each medicament50Value.Simultaneously according to Wadley method meters
Calculate two medicament different ratio synergy ratios（SR）, SR ＜ 0.5 be antagonism, 0.5≤SR≤1.5 be summation action, SR
＞ 1.5 is synergistic effect.Calculation formula is as follows：
Wherein：A, b is respectively active components A and active constituent B ratio shared in combination；
A is fluorine azoles bacterium aniline；
B is selected from one of kasugarnycin, jinggangmeisu, polyoxin, pesticide corrosion 120 kind.
Application Example two
For trying disease：Rice blast
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Fluorine azoles bacterium aniline and kasugarnycin active compound and the two different ratio mixture are determined by pilot study
Effective inhibition concentration range.
7 fluorine azoles bacterium aniline of table compounds the toxicity test analysis of results table to rice blast with kasugarnycin
As shown in Table 7, fluorine azoles bacterium aniline is matched in 1 80~80 ︰ 1 of ︰ with kasugarnycin to the synergic ratio of rice blast
Value SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~80 ︰ 1 shows synergistic effect, when fluorine azoles bacterium aniline and spring
For the proportioning of thunder mycin in 1 20~25 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is more than 2.20.It is tested through applicant
It was found that the optimum ratio of fluorine azoles bacterium aniline and kasugarnycin is 25：1、20：1、15：1、12：1、10：1、9：1、8：1、7：1、6：1、
5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：10、1：12、1：15、1：20, especially when
Fluorine azoles bacterium aniline is 3 with kasugarnycin weight ratio：Synergy ratio is maximum when 1, and synergistic effect is the most apparent.
Application Example three
For trying disease：Rice green smut
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Fluorine azoles bacterium aniline and jinggangmeisu active compound and the two different ratio mixture are determined by pilot study
Effective inhibition concentration range.
8 fluorine azoles bacterium aniline of table is with composite jinggangmycin to the toxicity test analysis of results table of rice green smut
As shown in Table 8, fluorine azoles bacterium aniline is matched in 1 80~80 ︰ 1 of ︰ with jinggangmeisu to the synergic ratio of rice green smut
Value SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~80 ︰ 1 shows synergistic effect, when fluorine azoles bacterium aniline and well
For the proportioning of ridge mycin in 1 25~25 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is more than 2.20.It is tested through applicant
It was found that the optimum ratio of fluorine azoles bacterium aniline and jinggangmeisu is 25：1、20：1、15：1、10：1、5：1、4：1、3：1、2：1、1：1、
2：3、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：11、1：13、1：15、1：20、1：25, especially work as fluorine
Azoles bacterium aniline is 2 with jinggangmeisu weight ratio：Synergy ratio is maximum when 3, and synergistic effect is the most apparent.
Application Example four：
For trying disease：Powdery mildew of cucumber
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Fluorine azoles bacterium aniline and polyoxin active compound and the two different ratio mixture are determined by pilot study
Effective inhibition concentration range.
Toxicity test result
9 fluorine azoles bacterium aniline of table compounds the toxicity test analysis of results table to powdery mildew of cucumber with polyoxin
As shown in Table 9, fluorine azoles bacterium aniline is matched in 1 80~80 ︰ 1 of ︰ with polyoxin to the synergic ratio of powdery mildew of cucumber
Value SR is all higher than 1.5, both illustrates that mixture shows synergistic effect in the range of 1 ︰, 80~80 ︰ 1, when fluorine azoles bacterium aniline with it is more
For the proportioning of antimycin in 1 25~25 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is more than 2.25.It is tested through applicant
It was found that the optimum ratio of fluorine azoles bacterium aniline and polyoxin is 25：1、20：1、15：1、10：1、5：1、4：1、3：1、2：1、1：1、
2：3、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：11、1：13、1：15、1：20、1：25, especially work as fluorine
Azoles bacterium aniline is 2 with polyoxin weight ratio：Synergy ratio is maximum when 3, and synergistic effect is the most apparent.
Application Example five
For trying disease：Rice sheath blight disease
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Fluorine azoles bacterium aniline and pesticide corrosion 120 active compound and the two different ratio mixture are determined by pilot study
Effective inhibition concentration range.
10 fluorine azoles bacterium aniline of table compounds the toxicity test analysis of results table to rice sheath blight disease with pesticide corrosion 120
As shown in Table 10, fluorine azoles bacterium aniline is matched in 1 80~80 ︰ 1 of ︰ with pesticide corrosion 120 to the synergic ratio of rice sheath blight disease
Value SR is all higher than 1.5, illustrates that the two mixture in the range of 1 ︰, 80~80 ︰ 1 shows synergistic effect, when fluorine azoles bacterium aniline and agriculture
For anti-120 proportioning in 1 25~25 ︰ 1 of ︰, synergistic effect is more prominent, and synergy ratio is more than 2.20.It is tested through applicant
It was found that the optimum ratio of fluorine azoles bacterium aniline and pesticide corrosion 120 is 25：1、20：1、15：1、10：1、8：1、5：1、4：1、3：1、2：1、1：
1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：15、1：20、1：When 25, especially when fluorine azoles bacterium aniline with
Pesticide corrosion 120 weight ratio is 1：Synergy ratio is maximum when 1, and synergistic effect is the most apparent.
It is found through experiment that：Fluorine azoles bacterium aniline and active constituent B compound after to the banded sclerotial blight, sclerotiniose, black in various crop
Fringe disease, powdery mildew, rust, downy mildew, epidemic disease, gray mold, brown spot, damping-off, droop, ring spot, rice blast, anthrax
The prevention of disease, angular leaf spot, false smut or bakanae disease has apparent synergistic effect, and synergy ratio SR is all higher than 1.5.
Effect experiment part：Test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, 20% fluorine azoles of comparison medicament
Bacterium aniline suspending agent（Autogamy）, 2% kasugarnycin wettable powder（It is purchased in market）, 5% jinggangmeisu aqua（It is purchased in market）, 3% polyoxin
Wettable powder（It is purchased in market）, 2% pesticide corrosion 120 aqua（It is purchased in market）.
Application Example hexafluoro azoles bacterium aniline and active constituent B and its compounding prevention wheat sharp eyespot test of pesticide effectiveness.
This test arrangement investigates wheat sharp eyespot disease index before Shaanxi Province Weinan City Pucheng County, medicine, occurs in disease
Initial stage dispenser 3 days after dispenser, investigates disease indexes and calculates preventive effect for 7 days, 15 days.Result of the test is as follows：
11 fluorine azoles bacterium aniline of table and active constituent B and its compounding prevention wheat sharp eyespot test of pesticide effectiveness
As can be seen from Table 11, wheat sharp eyespot can be effectively prevented after fluorine azoles bacterium aniline and active constituent B compoundings, through application
People, which tests, finds can also effectively to prevent after fluorine azoles bacterium aniline and active constituent B compounding wheat smut, powdery mildew, rust, brown
Pinta, control effect are above 96%, and better than the preventive effect of single dose, and preventive effect phase is long.Experiment scope of medication in target crop without
Harmful effect.
Seven fluorine azoles bacterium aniline of Application Example and active constituent B and its compounding prevention rice blast test of pesticide effectiveness.
This test arrangement investigates rice blast disease index before Shaanxi Province Hanzhong suburban area, medicine, occurs just in disease
Phase dispenser 5 days after dispenser, investigates disease indexes and calculates preventive effect for 15 days, 30 days.Result of the test is as follows：
12 fluorine azoles bacterium aniline of table and active constituent B and its compounding prevention rice blast test of pesticide effectiveness
As can be seen from Table 12, rice blast can be effectively prevented after fluorine azoles bacterium aniline and active constituent B compoundings, through application
People test find can also effectively to prevent after fluorine azoles bacterium aniline and active constituent B compounding rice sheath blight disease, powdery mildew, false smut,
Bakanae disease, control effect are above 96%, and better than the preventive effect of single dose, and preventive effect phase is long.To target crop in experiment scope of medication
It has no adverse effects.
Application Example octafluoro azoles bacterium aniline and active constituent B and its compounding prevention powdery mildew of cucumber test of pesticide effectiveness.
This test arrangement investigates powdery mildew of cucumber disease index before Xian District, Shanxi Province suburban area, medicine, occurs just in disease
Phase dispenser 3 days after dispenser, investigates disease indexes and calculates preventive effect for 7 days, 15 days.Result of the test is as follows：
13 fluorine azoles bacterium aniline of table and active constituent B and its compounding prevention powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 13, fluorine azoles bacterium aniline and active constituent B and its compounding prevention powdery mildew of cucumber, are tried through applicant
Issue after examination and approval can also effectively prevent after existing fluorine azoles bacterium aniline and active constituent B compounding gray mold of cucumber, damping-off, downy mildew, epidemic disease,
Angular leaf spot, droop, control effect are above 95%, and better than the preventive effect of single dose, and preventive effect phase is long.It is right in experiment scope of medication
Target crop has no adverse effects.
Nine fluorine azoles bacterium aniline of Application Example and active constituent B and its compounding prevention sclerotinia sclerotiorum test of pesticide effectiveness.
This test arrangement investigates sclerotinia sclerotiorum disease index before Shaanxi Province Hanzhong suburban area, medicine, occurs just in disease
Phase dispenser 3 days after dispenser, investigates disease indexes and calculates preventive effect for 10 days, 20 days.Result of the test is as follows：
14 fluorine azoles bacterium aniline of table and active constituent B and its compounding prevention sclerotinia sclerotiorum test of pesticide effectiveness
As can be seen from Table 14, sclerotinia sclerotiorum, prevention effect can effectively be prevented after fluorine azoles bacterium aniline and active constituent B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects in experiment scope of medication to target crop.
Ten fluorine azoles bacterium aniline of Application Example and active constituent B and its compounding prevention uncinula necator test of pesticide effectiveness.
This test arrangement investigates uncinula necator disease index before Shaanxi Province Weinan City Dali County, medicine, occurs in disease
Initial stage dispenser 10 days after dispenser, investigates disease indexes and calculates preventive effect for 20 days, 30 days.Result of the test is as follows：
15 fluorine azoles bacterium aniline of table and active constituent B and its compounding prevention uncinula necator test of pesticide effectiveness
As can be seen from Table 15, uncinula necator can be effectively prevented after fluorine azoles bacterium aniline and active constituent B compoundings, through application
People test find can also effectively to prevent after fluorine azoles bacterium aniline and active constituent B compounding downy mildew of garpe, gray mold, anthracnose,
Ring spot, control effect are above 96%, and better than the preventive effect of single dose, and preventive effect phase is long.To target crop in experiment scope of medication
It has no adverse effects.
The experiment by different places throughout the country obtains afterwards, and fluorine azoles bacterium aniline and kasugarnycin, resist jinggangmeisu more
Mycin, pesticide corrosion 120 compounding after in various crop banded sclerotial blight, sclerotiniose, smut, powdery mildew, rust, downy mildew, epidemic disease,
Gray mold, brown spot, damping-off, droop, ring spot, rice blast, anthracnose, angular leaf spot, false smut or bakanae disease etc. are common
The preventive effect of disease is more than 95%, and better than single dose preventive effect, synergistic effect is apparent.
Claims (4)
1. a kind of combination sterilization composition of fluorine-containing azoles bacterium aniline, effective active composition is active components A and active constituent B,
It is characterized in that：Active components A and active constituent B weight ratios are 1 ︰ 1, and the active components A is fluorine azoles bacterium aniline, active constituent
B is polyoxin.
2. the combination sterilization composition of fluorine-containing azoles bacterium aniline according to claim 1, it is characterised in that：Composition is made can
Wet powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion or microcapsule suspending agent.
3. the combination sterilization composition of fluorine-containing azoles bacterium aniline according to claim 2 is used to prevent the use of disease on crops
On the way.
4. purposes according to claim 3, it is characterised in that：The disease include banded sclerotial blight, sclerotiniose, smut,
Powdery mildew, rust, downy mildew, epidemic disease, gray mold, brown spot, damping-off, droop, ring spot, rice blast, anthracnose, angle spot
Disease, false smut or bakanae disease.
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| CN1870895A (en) * | 2003-10-23 | 2006-11-29 | 拜尔农作物科学股份公司 | Synergistic fungicidally active compound combinations |
| CN102469786A (en) * | 2009-07-07 | 2012-05-23 | 拜尔农作物科学股份公司 | Process for improving seedling growth and/or early emergence of crops |
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| CN1870895A (en) * | 2003-10-23 | 2006-11-29 | 拜尔农作物科学股份公司 | Synergistic fungicidally active compound combinations |
| CN102469786A (en) * | 2009-07-07 | 2012-05-23 | 拜尔农作物科学股份公司 | Process for improving seedling growth and/or early emergence of crops |
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Address after: 715500 Pucheng high tech Industrial Development Zone, Weinan, Shaanxi Patentee after: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 715500 Shaanxi Pucheng Weinan County agricultural base industrial park Patentee before: Shaanxi Meibang pesticide Co.,Ltd. |
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