CN104287878B - Blood intra-cavity support - Google Patents
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- CN104287878B CN104287878B CN201410471632.6A CN201410471632A CN104287878B CN 104287878 B CN104287878 B CN 104287878B CN 201410471632 A CN201410471632 A CN 201410471632A CN 104287878 B CN104287878 B CN 104287878B
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Abstract
本发明公开了一种血管腔内支架,包括管状的支架本体,所述支架本体的侧壁设有内外相通的通孔;所述通孔的孔心线向支架本体轴向一端倾斜,本发明的血管腔内支架,支架本体的侧壁设有内外相通的通孔,在分支血管处能保持血液在支架内外的流通,同时通孔的孔心线向支架本体轴向一端倾斜,将血管腔内支架以通孔内端朝血液流向倾斜的方式放置,避免了血流直接冲击血管内膜,且促进血液在支架内以层流的形式流动,不在通孔处产生涡流,大大降低血液流动对血管内膜造成的损伤,提高对血管内膜的保护性;同时因血管腔内支架植入处大部分血管内膜未被覆盖,局部血管内皮仍维持自身功能,减小了支架对内皮功能的干扰,从而达到较好的治疗效果。
The invention discloses a stent in a blood vessel cavity, which includes a tubular stent body, the side wall of the stent body is provided with a through hole communicating with the inside and outside; the center line of the through hole is inclined to one axial end of the stent body. The side wall of the stent body is provided with a through hole communicating with the inside and outside, which can maintain the circulation of blood inside and outside the stent at the branch blood vessel. The inner stent is placed in a way that the inner end of the through hole is inclined towards the blood flow direction, which avoids the direct impact of the blood flow on the intima of the blood vessel, and promotes the blood to flow in the form of laminar flow in the stent without generating eddy currents at the through hole, greatly reducing the impact of blood flow on the blood vessel. The damage caused by the vascular intima improves the protection of the vascular intima; at the same time, because most of the vascular intima is not covered in the place where the stent is implanted in the vascular cavity, the local vascular endothelium still maintains its own function, which reduces the impact of the stent on the endothelial function. Interference, so as to achieve a better therapeutic effect.
Description
技术领域technical field
本发明涉及一种医疗器械,尤其涉及一种血管腔内支架。The invention relates to a medical device, in particular to a stent in a blood vessel cavity.
背景技术Background technique
血管支架是在病变血管置入内支架以达到支撑狭窄闭塞段血管、扩大血管真腔、隔绝病变,减少血管弹性回缩及再塑形,保持管腔血流通畅的目的。利用腔内隔绝原理的微创介入治疗技术,它是用一套管径较细的输送系统,将被压缩状态的带支撑的支架送达血管病变位置,在准确定位后,将其释放并撑开病变血管,支架一般有覆膜支架和裸支架两种,现有技术中的裸支架多为丝网结构,网孔处血液流动依然对血管内膜造成较大的冲击,对内膜的保护性较差,治疗效果不佳;覆膜支架隔绝病变效果较为可靠,但是存在阻塞分支血管、内漏、破坏局部血管内皮功能等难以解决的问题,目前尚未有效、便捷的技术解决这些问题。Vascular stents are placed in diseased blood vessels to achieve the purpose of supporting stenotic and occluded blood vessels, expanding the true lumen of blood vessels, isolating lesions, reducing elastic retraction and reshaping of blood vessels, and maintaining smooth blood flow in the lumen. The minimally invasive interventional therapy technology using the principle of intracavitary isolation uses a delivery system with a small diameter to deliver the compressed stent with support to the position of the vascular lesion. After accurate positioning, it is released and braced. When opening diseased blood vessels, stents generally include covered stents and bare stents. Most of the bare stents in the prior art are wire mesh structures, and the blood flow at the mesh still has a large impact on the intima of the vessel. The stent-graft is more reliable in isolating lesions, but there are difficult problems such as blocking branch vessels, endoleaks, and destroying local vascular endothelial functions. Currently, there is no effective and convenient technology to solve these problems.
发明内容Contents of the invention
有鉴于此,本发明的目的是提供一种血管腔内支架,能保持血液在支架内外的流通,同时大大降低血液流动对血管内膜造成的损伤,提高对血管内膜的保护性,达到较好的治疗效果。In view of this, the purpose of the present invention is to provide a stent in the vascular cavity, which can maintain the circulation of blood inside and outside the stent, and at the same time greatly reduce the damage caused by the blood flow to the vascular intima, improve the protection of the vascular intima, and achieve better good therapeutic effect.
本发明的血管腔内支架,包括管状的支架本体,所述支架本体的侧壁设有内外相通的通孔;所述通孔的孔心线向支架本体轴向一端倾斜;The intravascular stent of the present invention includes a tubular stent body, the side wall of the stent body is provided with a through hole communicating with the inside and outside; the center line of the through hole is inclined toward one axial end of the stent body;
进一步,所述通孔沿支架本体周向和轴向均匀布置多个,各通孔的孔心线倾斜方向一致;Further, a plurality of said through holes are evenly arranged along the circumferential direction and the axial direction of the bracket body, and the inclination directions of the center lines of each through hole are consistent;
进一步,所述支架本体包括由回弹性板材卷曲而成的管状体;Further, the stent body includes a tubular body curled from a resilient plate;
进一步,所述支架本体还包括固定于管状体内壁的用于辅助回弹的条形回弹块;Further, the stent body also includes a strip-shaped rebound block fixed on the inner wall of the tubular body for assisting rebound;
进一步,所述条形回弹块沿管状体周向设置并且条形回弹块内侧面对应管状体轴向两侧边缘导圆角;Further, the strip-shaped rebound block is arranged along the circumference of the tubular body, and the inner surface of the strip-shaped rebound block corresponds to the rounded edges on both sides of the tubular body in the axial direction;
进一步,所述回弹性板材卷曲形成搭接边部,该搭接边部的内搭接边外侧面及外搭接边内侧面设有相匹配的用于阻碍回弹性板材回卷的锁扣;Further, the resilient sheet is curled to form an overlapping edge, and the outer surface of the inner overlapping edge and the inner surface of the outer overlapping edge of the overlapping edge are provided with matching locks for hindering the rewinding of the elastic sheet;
进一步,所述内搭接边的边缘设有用于将管状体回卷的操作孔;所述操作孔的孔心线沿管状体轴向设置。Further, the edge of the inner overlapping edge is provided with an operation hole for rewinding the tubular body; the center line of the operation hole is arranged along the axial direction of the tubular body.
本发明的有益效果是:本发明的血管腔内支架,支架本体的侧壁设有内外相通的通孔,在分支血管处能保持血液在支架内外的流通,同时通孔的孔心线向支架本体轴向一端倾斜,将血管腔内支架以通孔内端朝血液流向倾斜的方式放置,避免了血流直接冲击血管内膜,且促进血液在支架内以层流的形式流动,不在通孔处产生涡流,大大降低血液流动对血管内膜造成的损伤,提高对血管内膜的保护性;同时因血管腔内支架植入处大部分血管内膜未被覆盖,局部血管内皮仍维持自身功能,减小了支架对内皮功能的干扰;由于血流冲击斜向的通孔后,产生扩张血管的力,有利于支架与相应节段的血管紧密贴服;由于斜向的通孔的设计,使进入支架与血管之间的血液易于回流入支架管腔内,减小了支架外、内的压差,避免了覆膜支架的并发症“内漏”的发生条件;由于通孔密集排列,通孔之间的间隔薄且具有良好的柔韧性,当支架需要屈曲时,可以通过压缩小弯侧通孔的管径及拉伸大弯侧通孔的管径而易于达到,且支架的腔内面始终保持平滑而无皱褶。通过以上机制从而达到较好的治疗效果。The beneficial effect of the present invention is: the stent in the vascular cavity of the present invention, the side wall of the stent body is provided with a through hole communicating with the inside and outside, and the blood circulation inside and outside the stent can be maintained at the branch blood vessel, and the center line of the through hole is directed toward the stent. One end of the body axis is inclined, and the stent in the vascular cavity is placed in such a way that the inner end of the through hole is inclined towards the blood flow direction, which avoids the direct impact of the blood flow on the intima of the vessel, and promotes the flow of blood in the form of laminar flow in the stent, not in the through hole. The eddy current is generated at the place, which greatly reduces the damage caused by the blood flow to the vascular intima, and improves the protection of the vascular intima; at the same time, because most of the vascular intima where the stent is implanted in the vascular cavity is not covered, the local vascular endothelium still maintains its own function , which reduces the interference of the stent on the endothelial function; after the blood flow hits the oblique through hole, the force of expanding the blood vessel is generated, which is conducive to the close attachment of the stent to the blood vessel of the corresponding segment; due to the design of the oblique through hole, The blood that enters between the stent and the blood vessel is easy to flow back into the lumen of the stent, reducing the pressure difference between the outside and the inside of the stent, and avoiding the occurrence of "endoleak" as a complication of the covered stent; due to the dense arrangement of through holes, The space between the through holes is thin and has good flexibility. When the stent needs to buckle, it can be easily achieved by compressing the diameter of the through hole on the small bend side and stretching the diameter of the through hole on the large bend side, and the cavity of the stent The inner surface is always smooth and wrinkle-free. Through the above mechanisms to achieve a better therapeutic effect.
附图说明Description of drawings
图1为本发明的结构示意图;Fig. 1 is a structural representation of the present invention;
图2为本发明的横截面结构示意图;Fig. 2 is the cross-sectional structure schematic diagram of the present invention;
图3为本发明的单侧壁纵截面结构示意图。Fig. 3 is a schematic diagram of a longitudinal section structure of a single side wall of the present invention.
具体实施方式detailed description
图1为本发明的结构示意图;图2为本发明的横截面结构示意图;图3为本发明的单侧壁纵截面结构示意图,如图所示:本实施例的血管腔内支架,包括管状的支架本体,所述支架本体的侧壁设有内外相通的通孔1;所述通孔1的孔心线向支架本体轴向一端倾斜,能保持血液在支架内外的流通,同时将血管腔内支架以通孔1内端朝血液流向倾斜的方式放置,使血液在血管腔内支架内以层流的形式流动,不在通孔1处产生涡流,大大降低血液流动对血管内膜造成的损伤,提高对血管内膜的保护性,达到较好的治疗效果。Fig. 1 is a schematic structural view of the present invention; Fig. 2 is a schematic cross-sectional structural view of the present invention; Fig. 3 is a schematic structural view of a longitudinal section of a single side wall of the present invention, as shown in the figure: the vascular intraluminal stent of this embodiment includes a tubular The stent body, the side wall of the stent body is provided with a through hole 1 communicating with the inside and outside; the center line of the through hole 1 is inclined to the axial end of the stent body, which can maintain the circulation of blood inside and outside the stent, and at the same time make the blood vessel cavity The inner stent is placed in such a way that the inner end of the through hole 1 is inclined towards the blood flow direction, so that the blood flows in the form of laminar flow in the stent in the vascular cavity, and no vortex is generated at the through hole 1, which greatly reduces the damage caused by the blood flow to the vascular intima , to improve the protection of the vascular intima, to achieve a better therapeutic effect.
本实施例中,所述通孔1沿支架本体周向和轴向均匀布置多个,各通孔1的孔心线倾斜方向一致,通孔1的密度根据需要合理设置,布置多个通孔1能满足支架本体内外的通透性,减小对血管内膜的覆盖,以保持血液在支架内外的流通。In this embodiment, a plurality of through holes 1 are evenly arranged along the circumferential direction and axial direction of the stent body, the inclination directions of the center lines of each through hole 1 are consistent, and the density of through holes 1 is reasonably set according to needs, and a plurality of through holes are arranged 1 It can meet the permeability inside and outside the stent body, reduce the coverage of the intima of the blood vessel, so as to maintain the circulation of blood inside and outside the stent.
本实施例中,所述支架本体包括由回弹性板材卷曲而成的管状体2,便于支架本体的制作及通孔1的加工,降低制作成本,同时可将支架本体收卷成直径较小的筒状后使用专用器具将其夹紧,然后送至血管内的相应位置释放,利用回弹性板材的回弹性能膨开支撑于血管内壁,便于操作。In this embodiment, the stent body includes a tubular body 2 curled from a resilient sheet material, which is convenient for the manufacture of the stent body and the processing of the through hole 1, and reduces manufacturing costs. At the same time, the stent body can be rolled into a smaller diameter Clamp it with a special device after it is cylindrical, and then send it to the corresponding position in the blood vessel to release it. Utilize the rebound performance of the elastic plate to expand and support the inner wall of the blood vessel, which is easy to operate.
本实施例中,所述支架本体还包括固定于管状体2内壁的用于辅助回弹的条形回弹块3,进一步保证支架本体的回弹性能,增大对血管内壁的支撑力,保证治疗效果,同时使血管腔内支架定位稳定;条形回弹块3在支架本体轴向两端端部各布置一个,也可根据回弹性需要再在支架本体中部沿轴向均布多个,通过在支架本体轴向两端端部设置条形回弹块3能使支架本体轴向两端端部紧贴于血管内壁,抵抗血流冲击作用,避免血管腔内支架与血管剥离。In this embodiment, the stent body also includes a strip-shaped rebound block 3 fixed on the inner wall of the tubular body 2 for assisting rebound, further ensuring the rebound performance of the stent body, increasing the supporting force on the inner wall of the blood vessel, and ensuring treatment effect, and at the same time stabilize the positioning of the stent in the vascular cavity; one strip-shaped rebound block 3 is arranged at each end of the stent body in the axial direction, or more can be evenly distributed in the middle of the stent body in the axial direction according to the need for resilience. By arranging the strip-shaped resilient blocks 3 at both axial ends of the stent body, the axial ends of the stent body can be closely attached to the inner wall of the blood vessel, resisting the impact of blood flow, and avoiding the separation of the stent in the vascular lumen from the blood vessel.
本实施例中,所述条形回弹块3沿管状体2周向设置并且条形回弹块3内侧面对应管状体2轴向两侧边缘导圆角;对血液流动具有一定的导向功能,降低对血液的阻碍,使血液在血管腔内支架内以层流的形式流动。In this embodiment, the strip-shaped rebound block 3 is arranged along the circumferential direction of the tubular body 2, and the inner surface of the strip-shaped rebound block 3 corresponds to the rounded edges of the axial sides of the tubular body 2; it has a certain guide for blood flow Function, reduce the obstruction to the blood, make the blood flow in the form of laminar flow in the stent in the vascular lumen.
本实施例中,所述回弹性板材卷曲形成搭接边部,该搭接边部的内搭接边4外侧面及外搭接边5内侧面设有相匹配的用于阻碍回弹性板材回卷的锁扣6,阻碍回弹性板材回卷是指回弹性板材膨开形成管状体2后产生一定的保持力,使管状体2结构相对稳定,内搭接边4外侧面指内搭接边4沿管状体2径向向外的一侧面,外搭接边5内侧面是指外搭接边5沿管状体2径向向内的一侧面,通过管状体2自身的回弹性能使内搭接边4和外搭接边5紧压在一起,锁扣6为能够啮合的齿形结构,进而利用锁扣6的啮合阻碍回弹性板材回卷,使回弹性板材膨开后结构稳定,通过锁扣的调节,依血管管腔的变化,调节支架管径的大小,达到充分扩张、支撑血管的目的;锁扣可以有效防止支架回弹,保证支架支撑效果。In this embodiment, the elastic sheet material is curled to form an overlapping edge, and the outer surface of the inner overlapping edge 4 and the inner surface of the outer overlapping edge 5 of the overlapping edge are provided with matching parts for hindering the rebound of the elastic sheet material. The buckle 6 of the roll, hindering the rewinding of the elastic sheet means that the elastic sheet expands to form the tubular body 2 to generate a certain holding force, so that the structure of the tubular body 2 is relatively stable, and the outer surface of the inner lap edge 4 refers to the inner lap edge 4 along the radially outward side of the tubular body 2, the inner side of the outer lapping edge 5 refers to the radially inward side of the outer lapping edge 5 along the tubular body 2, through the resilience of the tubular body 2 itself the inner The overlapping edge 4 and the outer overlapping edge 5 are tightly pressed together, and the lock buckle 6 is a tooth-shaped structure that can be engaged, and then the engagement of the lock buckle 6 is used to hinder the rewinding of the resilient sheet material, so that the structure of the resilient sheet material is stable after expansion. Through the adjustment of the lock, the diameter of the stent can be adjusted according to the change of the vessel lumen to achieve the purpose of fully expanding and supporting the blood vessel; the lock can effectively prevent the stent from rebounding and ensure the support effect of the stent.
本实施例中,所述内搭接边4的边缘设有用于将管状体2回卷的操作孔7;所述操作孔7的孔心线沿管状体2轴向设置,可使用类似于镊子的工具通过操作孔7将回弹性板材收卷起来,便于血管腔内支架的放置和取出。In this embodiment, the edge of the inner overlapping edge 4 is provided with an operation hole 7 for rewinding the tubular body 2; the center line of the operation hole 7 is arranged axially along the tubular body 2, and can be used similar to tweezers The tool rolls up the resilient plate through the operation hole 7, which facilitates the placement and removal of the stent in the blood vessel cavity.
最后说明的是,以上实施例仅用以说明本发明的技术方案而非限制,尽管参照较佳实施例对本发明进行了详细说明,本领域的普通技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本发明技术方案的宗旨和范围,其均应涵盖在本发明的权利要求范围当中。Finally, it is noted that the above embodiments are only used to illustrate the technical solutions of the present invention without limitation. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be carried out Modifications or equivalent replacements without departing from the spirit and scope of the technical solution of the present invention shall be covered by the claims of the present invention.
Claims (5)
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| CN107280826B (en) * | 2017-06-01 | 2019-07-12 | 北京工业大学 | Tenon-and-mortise structure supporting rib vascular stent |
| CN109512559B (en) * | 2017-12-11 | 2021-05-28 | 河南理工大学 | A kind of preparation method of biodegradable tubular stent by ultrasound-induced micro-imprinting |
| CN108420576B (en) * | 2018-04-02 | 2019-12-06 | 青岛市即墨区人民医院 | A spaced non-slip vascular stent capable of chronic drug delivery |
| CN109259908B (en) * | 2018-09-26 | 2024-12-31 | 广州医科大学 | A novel drug-loaded airway stent and preparation method thereof |
| WO2022099491A1 (en) * | 2020-11-11 | 2022-05-19 | 北京积水潭医院 | Prosthesis for cancellous bone reconstruction |
| CN115464882B (en) * | 2022-10-09 | 2025-04-25 | 上海交通大学医学院附属新华医院 | A method for preparing a 3D printed sliding buckle infant bioabsorbable vascular stent |
| CN117918928B (en) * | 2024-03-21 | 2024-06-07 | 杭州亿科医疗科技有限公司 | Adjustable thrombus taking device |
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| WO1994021196A2 (en) * | 1993-03-18 | 1994-09-29 | C.R. Bard, Inc. | Endovascular stents |
| US6783543B2 (en) * | 2000-06-05 | 2004-08-31 | Scimed Life Systems, Inc. | Intravascular stent with increasing coating retaining capacity |
| US6090136A (en) * | 1996-07-29 | 2000-07-18 | Radiance Medical Systems, Inc. | Self expandable tubular support |
| US9107605B2 (en) * | 2000-11-17 | 2015-08-18 | Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
| CA2981561C (en) * | 2001-10-04 | 2020-08-25 | Neovasc Medical Ltd. | Flow reducing implant |
| US20030216804A1 (en) * | 2002-05-14 | 2003-11-20 | Debeer Nicholas C. | Shape memory polymer stent |
| CN2571402Y (en) * | 2002-06-12 | 2003-09-10 | 深圳市速航科技发展有限公司 | Self-expansion type carotid blood vessel support |
| ES2338560T3 (en) * | 2003-05-07 | 2010-05-10 | Advanced Bio Prosthetic Surfaces, Ltd. | IMPLANTABLE METALLIC IMPLANTS AND PROCEDURES TO MANUFACTURE THEM. |
| EP2213264A1 (en) * | 2009-01-30 | 2010-08-04 | Cordis Corporation | Reservoir eluting stent |
| CN203815663U (en) * | 2014-04-14 | 2014-09-10 | 林晨 | Caliber-adjustable jacket-type aorta aortamembrana tectoria support |
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