CN104720801B - Wireless stomach and intestine electrical activity mapping recorder and its application method - Google Patents

Abstract

The invention discloses a wireless gastrointestinal electric topographic map recorder and a method for using the same. The gastrointestinal electric topographic map recorder includes a gastrointestinal electric signal detection capsule placed inside the body and a gastrointestinal electric signal processing device outside the body; The intestinal electric signal detection capsule includes an input electrode, a wire, a signal selector, a signal amplification filter, a central processing unit, an encoder, a wireless transmitter and a battery. The shell of the gastrointestinal electrical signal detection capsule is capsule-shaped. The signal selector, signal amplification filter, central processing unit, encoder, and wireless transmitter are placed in the capsule shell, and the original gastric electric signal is obtained through an external receiving device. After processing by the data analysis processor, the electrogastric topographic map can be obtained. The invention obtains gastroelectric signals in different regions of the stomach by adjusting the position and direction of the capsule in the stomach through the magnet and the magnet. The capsule is convenient to swallow, non-invasive, has clinical application value, and provides a new research method for further research on gastric electrophysiology.

Description

Wireless gastrointestinal topography recorder and method of use thereof

technical field

The invention belongs to the technical field of medical devices, and relates to a wireless gastrointestinal electrotopography recorder and a using method thereof.

Background technique

Gastric myoelectric activity is the most basic physiological activity of the stomach, which controls the movement of the stomach. Gastric slow waves can be detected in the serosa, cavity, and body surface. The most widely used method for detecting gastric slow waves is surface electrogastrogram (EGG). However, in the actual medical process, we found that the current method of detecting gastric slow waves with a limited number of electrodes scattered and fixed on the target area can only detect the gastric electrical signals of a limited number of recording points. Due to the limitation of the quantity, it is difficult to accurately map the spread of electrical activity, so that it is impossible to prove whether there are various gastric arrhythmias caused by abnormal gastric electrical pacing or abnormal gastric electrical conduction, such as incomplete conduction block, complete conduction block, etc. Hysteresis, escape beat, ectopic pacing and functional reentry, etc.

Contents of the invention

In order to solve the above-mentioned problems in the prior art, the present invention provides a wireless gastrointestinal electrotopography recorder. The recorder regulates the position of the capsule in the stomach through wireless signals to obtain gastroelectric signals in different areas of the stomach.

The technical scheme that the present invention takes for solving this problem is:

The wireless gastrointestinal electrical topography recorder of the present invention includes a gastrointestinal electrical signal detection capsule placed in the subject's body and a gastrointestinal electrical signal processing device located outside the subject's body; the gastrointestinal electrical signal detection capsule includes input electrodes, Wire, signal selector, signal amplification filter, central processing unit, encoder, wireless transmitter, battery and capsule casing, input electrodes are connected to signal selector, and central processing unit is connected to signal selector, signal amplification filter, coding connected with the wireless transmitter; the battery is respectively connected with the signal selector, the signal amplification filter, the central processing unit, the encoder and the wireless transmitter; the gastrointestinal electrical signal processing device includes a wireless receiver, a decoder and a data processing device, and the data The processing device further includes a data analysis processor, a liquid crystal display and a data storage, the wireless receiver is connected to the decoder, the decoder is connected to the input end of the data analysis processor of the data processing device, and the output ends of the data analysis processor are respectively Connect with LCD display and data storage.

The surface of the capsule shell is covered by a plurality of mesh-like interwoven wires, and input electrodes are arranged at intersections of wires and wires; signal selectors, signal amplification filters, central processing units, encoders, wireless transmitters and batteries Set inside the capsule shell.

The recorder also includes magnets arranged above and below the examination bed, and a magnet arranged inside the gastrointestinal electric signal detection capsule; the magnets located above the examination bed are opposite in polarity to the magnets located below the examination bed.

The method for using the wireless gastrointestinal topography recorder includes the following steps:

In the first step, the subject is seated, turn on the power of the gastrointestinal electrical signal detection capsule; let the subject take the gastrointestinal electrical signal detection capsule with 50ml of water; the subject continues to drink 1000ml of water to partially fill the gastric cavity with liquid, The gastrointestinal electrical signal detection capsule sinks into the liquid in the gastric cavity, and uses water as the medium to conduct electrical signals;

In the second step, the subject first lies supine on the examination bed, the gastrointestinal electrical signal detection capsule moves into the magnetic field of the magnet, detects the gastric electrical signal on the back side of the gastric fundus for 15 minutes, and then moves the magnet toward the feet to drive the gastrointestinal tract The electrical signal detection capsule moved to the gastric antrum to detect the gastric electrical signals of the gastric body and the dorsal side of the gastric antrum for 15 minutes, and then placed the subject in a prone position to detect the gastric electrical signals of the gastric body and the ventral side of the gastric antrum for 15 minutes, and then moved to the head Move the magnet in the direction to drive the gastrointestinal electrical signal detection capsule to move to the gastric fundus, and detect the gastric electrical signal on the ventral side of the gastric fundus for 15 minutes;

In the third step, the gastrointestinal electrical signal detection capsule receives the gastrointestinal electrical signal through the input electrodes, and under the control of the central processor, the input electrodes are sequentially selected to transmit the gastrointestinal electrical signal to the signal amplification filter, and the amplified and filtered electrical signal passes through the central processing unit. After being processed by the processor, it is encoded by the encoder and transmitted to the body through the wireless transmitter;

In the fourth step, the wireless receiver of the in vitro gastrointestinal electrical signal processing device receives the electrical signal, decodes it through the decoder, and calibrates the signal baseline. The data analysis processor applies the data analysis software to calculate the surface potential map of the capsule, and then deduces the gastric mucosa The surface potential map integrates the gastric electrical signals from the dorsal side of the gastric fundus, the dorsal side of the gastric body and gastric antrum, the gastric body and the ventral side of the gastric antrum, and the ventral side of the gastric fundus to obtain a topographic map of the whole stomach and store it ;

In the fifth step, after the detection is completed, the gastrointestinal electrical signal detection capsule is excreted through the digestive tract.

The advantages and positive effects that the present invention has are:

In the wireless gastrointestinal electrotopography recorder of the present invention, a signal selector, a signal amplification filter, a central processing unit, an encoder, and a wireless transmitter are placed in a capsule shell, and the original electrogastric signal is obtained through an external receiving device. After processing by the data analysis processor, the electrogastric topographic map can be obtained. The invention obtains gastroelectric signals in different regions of the stomach by adjusting the position and direction of the capsule in the stomach through the magnet and the magnet. The capsule is convenient to swallow, non-invasive, has clinical application value, and provides a new research method for further research on gastric electrophysiology.

Description of drawings

Fig. 1 is the overall structure schematic diagram of the wireless gastrointestinal topography recorder of the present invention;

Fig. 2 is a schematic diagram of the external structure of the gastrointestinal electrical signal detection capsule of the present invention;

3 is a schematic diagram of the internal structure of the gastrointestinal electrical signal detection capsule of the present invention;

Fig. 4 is a schematic structural view of the gastrointestinal electrical signal processing device of the present invention;

Fig. 5 is a working state schematic diagram of the wireless gastrointestinal topography recorder of the present invention;

Fig. 6 is a detection process diagram of the recorder of the present invention.

Explanation of symbols of main components in the accompanying drawings:

1: Magnet 2: Exam table

3: Gastrointestinal electrical signal detection capsule 4: Subject to be tested

5: Gastrointestinal electrical signal processing device 6: Wireless receiver

7: Decoder 8: Data processing device

9: Input electrode 10: Wire

11: Magnet 12: Signal selector

13: Signal amplification filter 14: Central processing unit

15: Encoder 16: Wireless Transmitter

17: battery 18: data analysis processor

19: LCD display 20: Data memory

21: capsule shell 22: water

23: Gastric cavity.

detailed description

The wireless gastrointestinal electrotopography recorder of the present invention will be described in detail below with reference to the accompanying drawings and embodiments.

Fig. 1 is a schematic diagram of the overall structure of the wireless gastrointestinal electrotopography recorder of the present invention. As shown in Figure 1, the wireless gastrointestinal electrotopography recorder of the present invention includes an examination bed 2 and magnets 1 arranged above and below the examination couch 2, and a gastrointestinal electric signal detection capsule 3 placed in the body of the subject 4 and a gastrointestinal electrical signal processing device 5 located outside the body of the subject 4 . The magnets located above the couch are of opposite polarity to the magnets located below the couch.

Fig. 2 is a schematic diagram of the external structure of the gastrointestinal electrical signal detection capsule of the present invention; Fig. 3 is a schematic diagram of the internal structure of the gastrointestinal electrical signal detection capsule of the present invention. As shown in Figures 2 and 3, the gastrointestinal electrical signal detection capsule 3 includes an input electrode 9, a wire 10, a magnet 11, a signal selector 12, a signal amplification filter 13, a central processing unit 14, an encoder 15, a wireless transmitter 16 and battery 17. The shell of the gastrointestinal electrical signal detection capsule is in the shape of a capsule, and the surface of the capsule shell is covered with a plurality of interwoven wires 10 in a mesh shape, and input electrodes 9 are arranged at intersections of the wires.

Magnet 11, signal selector 12, signal amplification filter 13, central processing unit 14, encoder 15, wireless transmitter 16 and battery 17 are arranged inside the capsule shell. The input electrode 9 is connected with the signal selector 12, and the central processing unit 14 is connected with the signal selector 12, the signal amplification filter 13, the encoder 15 and the wireless transmitter 16 respectively. The battery 17 is respectively connected with the signal selector 12, the signal amplification filter 13, the central processing unit 14, the encoder 15 and the wireless transmitter 16.

Fig. 4 is a schematic structural diagram of the gastrointestinal electrical signal processing device of the present invention. As shown in Figure 4, the gastrointestinal electrical signal processing device 5 includes a wireless receiver 6, a decoder 7, and a data processing device 8, and the data processing device 8 includes a data analysis processor 18, a liquid crystal display 19, and a data storage device 20. The device 7 is connected to the input end of the data analysis processor 18, and the output end of the data analysis processor 18 is respectively connected to the liquid crystal display 19 and the data storage 20.

Before using the above-mentioned wireless gastrointestinal topography recorder for detection, the subjects were required to fast for more than 6 hours, and drugs that affect gastrointestinal motility were prohibited for 3 days before the detection.

Fig. 5 is a schematic view of the working state of the wireless gastrointestinal topography recorder of the present invention; Fig. 6 is a detection process diagram of the recorder of the present invention. As shown in Figure 5 and Figure 6, the use of the recorder is as follows:

In the first step, the subject is seated, and the power of the gastrointestinal electrical signal detection capsule is turned on; the subject is given the gastrointestinal electrical signal detection capsule with 50ml of water 22; the subject continues to drink 1000ml of water, so that the gastric cavity 23 is partially filled with liquid , so that the gastrointestinal electrical signal detection capsule sinks into the liquid in the gastric cavity, and conducts electrical signals with water as the medium;

In the second step, the subject first lies supine on the examination bed, the gastrointestinal electrical signal detection capsule moves into the magnetic field of the magnet, detects the gastric electrical signal on the back side of the gastric fundus for 15 minutes, and then moves the magnet toward the feet to drive the gastrointestinal tract The electrical signal detection capsule moved to the gastric antrum to detect the gastric electrical signals of the gastric body and the dorsal side of the gastric antrum for 15 minutes, and then placed the subject in a prone position to detect the gastric electrical signals of the gastric body and the ventral side of the gastric antrum for 15 minutes, and then moved to the head Move the magnet in the direction to drive the gastrointestinal electrical signal detection capsule to move to the gastric fundus, and detect the gastric electrical signal on the ventral side of the gastric fundus for 15 minutes;

In the third step, the gastrointestinal electrical signal detection capsule receives the gastrointestinal electrical signal through the input electrodes, and under the control of the central processor, the input electrodes are sequentially selected to transmit the gastrointestinal electrical signal to the signal amplification filter, and the amplified and filtered electrical signal passes through the central processing unit. After being processed by the processor, it is encoded by the encoder and transmitted to the body through the wireless transmitter;

In the fourth step, the wireless receiver of the in vitro gastrointestinal electrical signal processing device receives the electrical signal, decodes it through the decoder, and calibrates the signal baseline. The data analysis processor applies the data analysis software to calculate the surface potential map of the capsule, and then deduces the gastric mucosa The surface potential map integrates the gastroelectric signals from the dorsal side of the gastric fundus, the dorsal side of the gastric body and gastric antrum, the gastric body and the ventral side of the gastric antrum, and the ventral side of the gastric fundus to obtain a topographic map of the whole stomach and store it;

In the fifth step, after the detection is completed, the gastrointestinal electrical signal detection capsule is excreted through the digestive tract.

During the detection process, the position of the gastrointestinal electric signal detection capsule is controlled through the cooperation of the magnet and the magnet. And the magnet has a fixed direction in the magnetic field formed by the upper and lower two magnets, so that the gastrointestinal electrical signal detection capsule is fixed in a certain direction for detection, and the detected gastric electrical signal is more stable and accurate.

Claims (2)

1. A wireless gastrointestinal electrical topographic map recorder, characterized in that: the recorder includes a gastrointestinal electrical signal detection capsule (3) placed in the subject's body and a gastrointestinal electrical signal processing device positioned outside the subject's body (5); Gastrointestinal electrical signal detection capsule (3) comprises input electrode (9), lead wire (10), signal selector (12), signal amplification filter (13), central processing unit (14), encoder ( 15), wireless transmitter (16), battery (17) and capsule shell (21), input electrode (9) is connected with signal selector (12), central processing unit (14) is connected with signal selector (12), respectively Signal amplification filter (13), encoder (15) and wireless transmitter (16) are connected; Battery (17) is respectively connected with signal selector (12), signal amplification filter (13), central processing unit (14), Encoder (15) is connected with wireless transmitter (16); Gastrointestinal electric signal processing device (5) comprises wireless receiver (6), decoder (7) and data processing device (8), data processing device (8) Including data analysis processor (18), liquid crystal display (19) and data memory (20), wireless receiver (6) is connected with decoder (7), decoder (7) and data processing device (8) The input end of the data analysis processor (18) is connected, and the output end of the data analysis processor (18) is connected with the liquid crystal display (19) and the data storage (20) respectively; The surface of the capsule shell (21) is covered by multiple A net-like interwoven wire (10) is covered, and an input electrode (9) is arranged at the intersection of the wire and the wire; a signal selector (12), a signal amplification filter (13), a central processing unit (14), an encoder (15), wireless transmitter (16) and battery (17) are arranged inside the capsule shell. 2. The wireless gastrointestinal electrotopography recorder according to claim 1, characterized in that: the recorder also includes magnets (1) arranged above and below the examination table (2), and magnets (1) arranged on the gastrointestinal electric signal The magnets (11) inside the capsule (3) are tested; the magnets located above the examination bed are opposite in polarity to the magnets located below the examination bed.