CN104965562B - Computing device is looked into a kind of Platelet Index test and appraisal soon - Google Patents
Computing device is looked into a kind of Platelet Index test and appraisal soon Download PDFInfo
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- CN104965562B CN104965562B CN201510363678.0A CN201510363678A CN104965562B CN 104965562 B CN104965562 B CN 104965562B CN 201510363678 A CN201510363678 A CN 201510363678A CN 104965562 B CN104965562 B CN 104965562B
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- fanning tray
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- 238000012360 testing method Methods 0.000 title claims abstract description 9
- MXBCYQUALCBQIJ-RYVPXURESA-N (8s,9s,10r,13s,14s,17r)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol;(8r,9s,13s,14s,17r)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthrene-3,17-diol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1.C1CC[C@@H]2[C@H]3C(=C)C[C@](CC)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 MXBCYQUALCBQIJ-RYVPXURESA-N 0.000 claims 3
- 238000013461 design Methods 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 3
- 238000011156 evaluation Methods 0.000 abstract description 3
- 238000010276 construction Methods 0.000 abstract description 2
- 210000001772 blood platelet Anatomy 0.000 description 40
- 102000004625 Aspartate Aminotransferases Human genes 0.000 description 26
- 108010003415 Aspartate Aminotransferases Proteins 0.000 description 26
- 238000005259 measurement Methods 0.000 description 11
- 208000034189 Sclerosis Diseases 0.000 description 10
- 230000002440 hepatic effect Effects 0.000 description 10
- 210000004185 liver Anatomy 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 208000019425 cirrhosis of liver Diseases 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 210000005229 liver cell Anatomy 0.000 description 2
- 208000019423 liver disease Diseases 0.000 description 2
- 206010003445 Ascites Diseases 0.000 description 1
- 206010019668 Hepatic fibrosis Diseases 0.000 description 1
- 206010061998 Hepatic lesion Diseases 0.000 description 1
- 206010067125 Liver injury Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002091 elastography Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 238000012317 liver biopsy Methods 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
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- 238000011069 regeneration method Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention belongs to medical treatment to detect equipment technology field, it is related to a kind of Platelet Index test and appraisal and looks into computing device soon, agent structure is to be carved with outer ring PLT graduation marks and inner ring AST graduation marks, every 10 scale note, one scale value respectively on bottom disc, and 0 degree of graduation mark is red thick line；The radius of fanning tray is identical with the radius of bottom disc, fanning tray is the sector structure that central angle is 120 degree, the left side bearing of fanning tray is red thick line, rivet is riveted together fanning tray and bottom disc by the first rivet hole and the second rivet hole, bottom disc and fanning tray can be around rivets with respect to flexible rotating, when fanning tray rotates clockwise, α angles are formed between 0 degree of graduation mark and the left side bearing of fanning tray；The trouble that formula evaluation is used after detecting every time is saved, intuitively can judge simply and rapidly and accurately state of an illness result, its overall construction design is simple, and use principle is safe and reliable, and use is easy to operate, and application environment is friendly.
Description
Technical field：
The invention belongs to medical treatment to detect equipment technology field, is related to a kind of Platelet Index test and appraisal and looks into computing device soon, special
It is not one kind can whether there is the hepatic sclerosis patient's condition according to aspartate transaminase (AST) value and blood platelet (PLT) value Fast Evaluation patient
And the calculating disk of curative effect, there is functional characteristics that is easy to operate, inquiring about soon.
Background technology：
Hepatic sclerosis is clinical common chronic progressive hepatopathy, by one or more causes of disease are long-term or repeated action formed
Diffusivity hepatic lesion, there are extensive necrosis of liver cells, regeneration of remaining liver cell nodules, connective tissue proliferation in Histopathology
With fiber every formation, cause lobuli hepatis structure to be destroyed and formed with pseudolobuli, liver gradually deforms, and is hardened and develops into hepatic sclerosis；
Liver fibrosis is the pathological change caused by chronic liver damage caused by many reasons, and it is excessive to show as the outer interstitial components of liver inner cell
Deposit singularly, and influence the function of liver, be chronic liver disease develop into hepatic sclerosis must through stage；Liver function is very complicated,
Clinical test method is a lot, but is also difficult to reflect repertoire state, and various results of laboratory test need to combine clinical manifestation and other inspections
Comprehensive analysis is looked into, the goldstandard for the measurement degree of hepatic fibrosis generally acknowledged in the world at present is liver biopsy, but this method is invasion
Operation, risk is larger, and patient's acceptance level is low, carries out difficult；Transient elastography progressively turns into liver fibrosis diagnosis in recent years
Important references, but its result is influenceed by many factors such as obesity, ALT, bilirubin and ascites, and price is costly, no
Easily popularization；APASL session in 2015, WHO organize to specifically mention in the first guide on chb of issue：In resource
In the case of limited, it is recommended to use aspartate transaminase (AST) Platelet Index (APRI) is as the first choice for assessing hepatic sclerosis
Non-Invasive detection method, but the points-scoring system is complex.Therefore, seek to design a kind of Platelet Index (APRI) test and appraisal
Computing device is looked into soon, AST and PLT values are engraved on same Zhang Yuanpan according to corresponding relation, can be according to the reality clinically measured
AST values, corresponding standard PLT values are found out, by comparing actual measurement PLT values and standard PLT values, it is hard quickly to judge patient whether there is liver
Change, structure operation is simple, is easy to popularize；But current such technical scheme is there is not yet report, also has no using such device.
The content of the invention：
The shortcomings that goal of the invention of the present invention is to overcome prior art to exist, with reference to clinical practice demand, propose design
Computing device is looked into a kind of Platelet Index test and appraisal soon, to solve existing hepatic sclerosis inspection method complexity, somewhat expensive, to patient's body
There is the problem of aggressive risk in body, be easy to clinician quick and precisely to judge hepatic sclerosis result, evade checking process to patient
Aggressive risk, cheap caused by body, is easy to popularize.
In order to realize foregoing invention purpose, computing device is looked into Platelet Index test and appraisal of the present invention soon, its body junction
Structure includes bottom disc, outer ring PLT graduation marks, inner ring AST graduation marks, outer ring PLT scale values, inner ring AST scale values, 0 degree of quarter
Spend line, chassis word, the first rivet hole, fanning tray, left side bearing, rivet fixed area, the second rivet hole, fanning tray word, rivet and α folders
Angle；Outer ring PLT graduation marks and inner ring AST graduation marks are carved with according to 360 degree of grooves of circle respectively on the bottom disc of PVC material,
Outer ring PLT graduation marks were per being once 1.25U/L, and every inner ring AST graduation marks had once been 1U/L, every 10 scale note, one scale value,
Scale value is only marked in the range of 0~240 degree of bottom disc, and the outer ring PLT scale values of same angle are the inner rings of same angle
AST scale values standard PLT values for being calculated when APRI indexes are 2,0 degree of graduation mark are red thick line, the circle of bottom disc
The content of the chassis word of heart bottom is " outer ring is PLT values, and often degree is 1.25U/L " and " inner ring is AST values, and often degree is 1U/
L ", chassis word are 0.5~1mm of depth character cut in bas-relief, and the first rivet hole is provided with the center of bottom disc；The fanning tray of PVC material
Radius it is identical with the radius of bottom disc, fanning tray is that central angle is 120 degree of sector structure, the left side bearing of fanning tray for it is red slightly
Line, the center of circle of fanning tray are provided with rivet fixed area, are also provided with the second rivet hole on the center of circle of fanning tray, the fanning tray word in fanning tray
Content is：" APRI scorings are looked into soon calculates disk " and " PLT values APRI in red angle>2 ", fanning tray word is 0.5~1mm of height
Type, fanning tray is placed on above bottom disc and the center of circle is alignd, rivet is by the first rivet hole and the second rivet hole by fanning tray
Riveted together with bottom disc, bottom disc and fanning tray can be around rivets with respect to flexible rotating, when fanning tray rotates clockwise, 0
Spend and α angles are formed between graduation mark and the left side bearing of fanning tray；In the use of the present invention, first measure the actual AST values and reality of patient
Border PLT values, graduation mark corresponding to surveying AST values is found in inner ring AST graduation marks, fanning tray is rotated clockwise, makes a left side for fanning tray
Graduation mark corresponding to actual measurement AST values is pointed in sideline, while points to the outer ring PLT graduation marks of same angle, and observation is judged outside this
The size of the scale value enclosed at PLT graduation marks and actual measurement PLT values, if actual measurement PLT values fall within α angles, illustrate APRI>2,
Suspect that patient has hepatic sclerosis；If actual measurement PLT values fall outside α angles, illustrate APRI<2, judge that patient may not be that liver is hard
Change.
The present invention compared with prior art, saves the trouble that formula evaluation is used after detecting every time, can be intuitively simple
And rapidly and accurately judge state of an illness result；Its overall construction design is simple, and use principle is safe and reliable, and preparation cost is low, uses
Easy to operate, time saving and energy saving, application environment is friendly.
Brief description of the drawings：
Fig. 1 is the integral surface principle schematic diagram of the present invention.
Fig. 2 is the overall cross-section structure principle schematic of the present invention.
Fig. 3 is the chassis structure principle schematic of the present invention.
Fig. 4 is the fanning tray principle schematic diagram of the present invention.
Embodiment：
Below by specific embodiment and with reference to accompanying drawing, the invention will be further described.
Embodiment：
Computing device is looked into the Platelet Index test and appraisal that the present embodiment is related to soon, and its agent structure includes：It is bottom disc 1, outer
Enclose PLT graduation marks 2, inner ring AST graduation marks 3, outer ring PLT scale values 4, inner ring AST scale values 5,0 degree of graduation marks 6, chassis words
7th, the first rivet hole 8, fanning tray 9, left side bearing 10, rivet fixed area 11, the second rivet hole 12, fanning tray word 13, rivet 14 and α folders
Angle 15；Outer ring PLT graduation marks 2 and inner ring AST scales are carved with the bottom disc 1 of PVC material according to 360 degree of grooves of circle respectively
Line 3, outer ring PLT graduation marks 2 were per being once 1.25U/L, and inner ring AST graduation marks 3 per being once 1U/L, carve by every 10 scale note one
Angle value, scale value are only marked in the range of 0~240 degree of bottom disc, and the outer ring PLT scale values 4 of same angle are same angles
Inner ring AST scale values 5 when APRI indexes are 2 the standard PLT values that are calculated, 0 degree of graduation mark 6 be red thick line, bottom
The content of the chassis word 7 of the center of circle bottom of disk 1 for " outer ring be PLT values, often spend be 1.25U/L " with " inner ring is AST values,
Often degree is 1U/L ", and chassis word 7 is 0.5~1mm of depth character cut in bas-relief, and the first rivet hole 8 is provided with the center of bottom disc 1；
The radius of the fanning tray 9 of PVC material is identical with the radius of bottom disc 1, and fanning tray 9 is that central angle is 120 degree of sector structure, fanning tray
9 left side bearing 10 is red thick line, and the center of circle of fanning tray 9 is provided with rivet fixed area 11, the second riveting is also provided with the center of circle of fanning tray 9
Nail 12, the content of the fanning tray word 13 in fanning tray 9 are：" APRI scorings are looked into soon calculates disk " and " PLT values are in red angle
APRI>2 ", fanning tray word 13 is 0.5~1mm of height type, and fanning tray 9 is placed on into bottom disc 1 above and the center of circle is alignd, riveting
Nail 14 is riveted together fanning tray 9 and bottom disc 1 by the first rivet hole 8 and the second rivet hole 12, bottom disc 1 and fanning tray
9 can be around rivet 14 with respect to flexible rotating, when fanning tray 9 rotates clockwise, shape between 0 degree of graduation mark 6 and the left side bearing 10 of fanning tray
Into α angles 15.
The present embodiment when in use, first measures the actual AST values of patient and actual PLT values, in inner ring AST graduation marks 3
Graduation mark corresponding to finding actual measurement AST values, rotates clockwise fanning tray 9, the left side bearing 10 of fanning tray 9 is pointed to actual measurement AST values and corresponds to
Graduation mark, while point to the outer ring PLT graduation marks 2 of same angle, observation judges the scale at this outer ring PLT graduation marks 2
The size of value and actual measurement PLT values, if actual measurement PLT values fall within α angles 15, illustrate APRI>2, suspect that patient has hepatic sclerosis；
If actual measurement PLT values fall outside α angles 15, illustrate APRI<2, judge that patient may not be hepatic sclerosis, can further check
Other specification.The present embodiment is in Clinical practice, and its rate of accuracy reached to more than 98%, easy to use and flexible is simple to operate, is worth
Popularization and application.
Claims (1)
1. computing device is looked into a kind of Platelet Index test and appraisal soon, it is characterised in that agent structure includes bottom disc, outer ring PLT is carved
Spend line, inner ring AST graduation marks, outer ring PLT scale values, inner ring AST scale values, 0 degree of graduation mark, chassis word, the first rivet hole,
Fanning tray, left side bearing, rivet fixed area, the second rivet hole, fanning tray word, rivet and α angles；Respectively according to a circle on bottom disc
360 degree of grooves, are carved with outer ring PLT graduation marks and inner ring AST graduation marks, and outer ring PLT graduation marks were per being once 1.25U/L, inner ring
For AST graduation marks per being once 1U/L, every 10 scale note, one scale value, scale value is only marked on 0~240 degree of scope of bottom disc
Interior, the outer ring PLT scale values of same angle are that the inner ring AST scale values of same angle are calculated when APRI indexes are 2
Standard PLT values, 0 degree of graduation mark are red thick line, and the content of the chassis word of the center of circle bottom of bottom disc is " outer ring PLT
Value, often degree be 1.25U/L " and " inner ring be AST values, and it is 1U/L " often to spend, and chassis word is 0.5~1mm of depth character cut in bas-relief, bottom
The first rivet hole is provided with the center of disk；The radius of fanning tray is identical with the radius of bottom disc, and fanning tray is that central angle is 120 degree
Sector structure, the left side bearing of fanning tray is red thick line, and the center of circle of fanning tray is provided with rivet fixed area, also opened on the center of circle of fanning tray
There is the second rivet hole, the content of the fanning tray word in fanning tray is：" APRI scorings are looked into soon calculates disk " and " PLT values are in red angle
Interior APRI>2 ", fanning tray word is 0.5~1mm of height type, and fanning tray is placed on above bottom disc and the center of circle is alignd, rivet
Fanning tray and bottom disc are riveted together by the first rivet hole and the second rivet hole, bottom disc and fanning tray can be around rivets
With respect to flexible rotating, when fanning tray rotates clockwise, α angles are formed between 0 degree of graduation mark and the left side bearing of fanning tray.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510363678.0A CN104965562B (en) | 2015-06-26 | 2015-06-26 | Computing device is looked into a kind of Platelet Index test and appraisal soon |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510363678.0A CN104965562B (en) | 2015-06-26 | 2015-06-26 | Computing device is looked into a kind of Platelet Index test and appraisal soon |
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| Publication Number | Publication Date |
|---|---|
| CN104965562A CN104965562A (en) | 2015-10-07 |
| CN104965562B true CN104965562B (en) | 2017-11-17 |
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| CN201510363678.0A Expired - Fee Related CN104965562B (en) | 2015-06-26 | 2015-06-26 | Computing device is looked into a kind of Platelet Index test and appraisal soon |
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