CN104984185A - Traditional Chinese medicine preparation for suppurative meningitis and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for suppurative meningitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for suppurative meningitis and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine preparation for suppurative meningitis comprises herba houttuyniae, herba patriniae, rabdosia rubescens, caulis sargentodoxae, honey suckle, folium isatidis, radix isatidis, philippine violet herbs, chrysanthemum indicum, ligusticum wallichii, Chinese brake herbs, peach kernels, red flowers, radix astragali, cassia twigs, spina gleditsiae, suberect spatholobus stems, poria cocos, rhizoma alismatis, uniflower swisscentaury roots, phillyrin, glabrous greenbrier rhizome and humifuse euphorbia herbs. According to different characteristics of all the traditional Chinese medicine, all the raw materials are cleaned, cut into pieces, pretreated, blended in proportion and manufactured into the traditional Chinese medicine preparation for suppurative meningitis through the special method. The traditional Chinese medicine preparation for suppurative meningitis has the effects of clearing heat, conducting detoxification, dispelling wind, relieving pain, activating blood to promote menstruation, promoting the circulation of qi and eliminating dampness. The combination and manufacturing method is unique; it is proved in clinical trials that the preparation for suppurative meningitis is remarkable in curative effect, short in treatment cycle and low in price, has no adverse effect and no toxic and side effect and has broad market application prospects.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for purulent meningitis, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Purulent meningitis (purulent meningitis) is one of disease of whole world sickness rate and high case fatality rate.The Epidemiology in country variant and region is not quite similar.The sickness rate of the U.S. is 3/ (100,000 *).The sickness rate of developing country is higher, may be relevant with shortage vaccination.Being the meninges inflammation caused by suppurative bacterium infects, is the common pyogenic infection of central nervous system.Usual Acute onset, is apt to occur in infant and child and more than 60 years old old people.
Primary disease belongs to pathogenic warmth convict, first should distinguish the weight of heresy when facing card, card along inverse.General evil poison point to import edema caused by disorder of QI, battalion point, blood system person into gradually by defending, and is that saequential transmission patient's condition is partially light.If heresy is by defending point the pathogen attacking the pericardium adversely or directly entering nutrient blood, be adverse transference, patient's condition is heavier.
At present, purulent meningitis there is no specific short.Ro-13-9904, cefotaxime etc. have certain curative effect, need operative treatment when being even in a bad way.But the long-term or short time uses these medicines to treat, obesity, hirsutism, hypertension, edema, Nausea and vomiting, dizziness can be caused, constipation etc. series of side effects symptom, and the dependency created, after drug withdrawal, primary affection knock-on increases the weight of the side effect with secondary, and patient can be made to produce very large misery, therapeutic process again and again, DeGrain, expense is high, causes larger pressure at heart and ailing pressure to patient.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for purulent meningitis, it is remarkable that this Chinese medicine preparation has therapeutic effect for therapeutic purulent meningitis, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of purulent meningitis repeatedly.The present invention has that therapeutic effect is remarkable, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
The effect of Chinese medicine of the present invention:
Wherein:
Herba Houttuyniae: be the dry aerial parts of saururaceae plant houttuynia cordata Houttuynia cordata Thunb..Nature and flavor: pungent, are slightly cold.Return lung meridian.Effect: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.Record in " detailed outline ": dispel the heat malicious carbuncle, skin ulcer hemorrhoid proctoptosis ， Duan Malaria disease, separate Nao poison.
Herba Patriniae: be Herba Patriniae section plant Hemerocallis citrina Baroni dragon bud Patrinia scabiosaefolia Fisch. ex Link., patrima villosa (bitter vegetarian) P. villosa (Thunb.) Juss., with root stock and root, all herbal medicine.Nature and flavor: pungent, bitter, cool.Return through stomach, large intestine, Liver Channel.Effect: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Caulis Sargentodoxae: be the dry rattan of plants of Lardizabalaceae Caulis Sargentodoxae Sargentodoxa cuneata (Oliv.) Rehd.et Wils..Nature and flavor: bitter are flat.Return large intestine, Liver Channel.Effect: heat-clearing and toxic substances removing, invigorates blood circulation, and dispels the wind.For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling.Record in " simple and easy medical herbs ": control bones and muscles pain, chase after wind, strong waist knee joint, tonifying YANG thing.
Flos Lonicerae: the flower that dry flower or band for caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypoglauca Miq., Flos Lonicerae (hair calyx Radix Ophiopogonis) Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. are just opened.Nature and flavor: sweet, cold.Return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.Record in " the SHENGCAO property of medicine is standby to be wanted ": energy eliminating carbuncle cellulitis furunculosis, dysentery relieving disease, washes chancre, peeling skin heat in blood.
Folium Isatidis: be the dried leaves of cruciferae isatis Isatis indigotica Fort..Nature and flavor: bitter, cold.GUIXIN, stomach warp.Effect: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Join the army for pathogenic warmth, unconsciousness due to high fever, sends out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.Record in " detailed outline ": main pyrotoxic dysentery, jaundice, sore throat, erysipelas.
Radix Isatidis: be the dry root of cruciferae isatis Isatis indigotica Fort..Nature and flavor: bitter, cold.GUIXIN, stomach warp.Effect: heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.Record in " classifying herbal ": separate all malicious malignant boil, loose poison reduces internal heat, smash juice or clothes or painting.
Herba Violae: be the dry herb of Violaceae Chinese violet Viola yedoensis Makino.Nature and flavor: bitter, acrid, cold.GUIXIN, Liver Channel.Effect: heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.
Flos Chrysanthemi Indici: be the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..Nature and flavor: sweet, bitter, are slightly cold.Return lung, Liver Channel.Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.Record in " herbal classic ": main all dizziness due to wind, to swell and ache, order for de-, lacrimation, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, sharp vim and vigour.
Rhizoma Chuanxiong: be samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort.(or Ligusticum wallichii Franch.) dry rhizome.Nature and flavor: pungent, temperature.Return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Record in " Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken Disorder ties stagnated blood, supports fresh blood, puts on flesh, serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, and scrofula wart is gone to live in the household of one's in-laws on getting married, skin ulcer scabies, and evacuation of pus repercussive blood.
Semen Persicae: be the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Record in " herbal classic ": main blood stasis, blood closes lump in the abdomen, pathogen, kills small worm." not Lu ": only cough with dyspnea, disappear hardness in the epigastrium, and except soldier hits blood cruelly, broken lump in the abdomen, promotes blood circulation, pain relieving.
Flos Carthami: be the dried floral of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor: pungent, temperature.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache." detailed outline ": invigorate blood circulation, moisturizes, pain relieving, loose swollen, stimulates the menstrual flow.
The Radix Astragali: be the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..Nature and flavor: sweet, temperature.Return lung, spleen channel.Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Spring, Xia Erji gather, and except defoliation, dry, or section is dried.Nature and flavor: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Cure mainly diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Spina Gleditsiae: be the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return liver, stomach warp.Effect: detumescence poison holding, evacuation of pus, parasite killing.For carbuncle from the beginning of or difficulty in discharging of pus; External treatment scabies leprosy.Record in " detailed outline ": control carbuncle, acute mastitis, scrofula caused by pathogenic wind malignant boil, retention of placenta, parasite killing.
Caulis Spatholobi: be the dry rattan of leguminous plant spatholobus suberectus Spatholobus suberectus Dunn.Nature and flavor: bitter, sweet, temperature.Return liver, kidney channel.Cure mainly blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea, amenorrhea, rheumatic arthralgia, paralysis and numbness, blood deficiency and yellow complexion.
Poria: be the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Nature and flavor: sweet, light are flat.GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.Record in " Japan hanako materia medica ": mend five kinds of strain and seven kinds of impairment, antiabortive, warm waist knee joint, happy Fructus Alpiniae Oxyphyllae, only forgetful.
Rhizoma Alismatis: be the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis Alisma orientalis (Sam.) Juzep..Nature and flavor: sweet, cold.Return kidney, urinary bladder channel.Effect: diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.Record in " herbal classic ": main anemofrigid-damp arthralgia, breast is difficult, and disappear water, supports the five internal organs, physical strength profiting, fertile strong.
Radix Rhapontici: be the dry root of feverfew centaurea monanthos Georgi Rhaponticum uniflorum (L.) DC..Nature and flavor: bitter, cold.Return stomach warp.Effect: heat-clearing and toxic substances removing, eliminating carbuncle, stimulating milk secretion, relaxing muscles and tendons is promoted blood circulation.Swell and ache for acute mastitis, carbuncle carbuncle on the back, scrofula sore, galactostasis, arthralgia chiefly caused by damp pathogen contracture.Record in " herbal classic ": main skin heat, malignant boil cellulitis hemorrhoid, arthralgia chiefly caused by damp pathogen, lower milk.
Fructus Forsythiae: be the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Nature and flavor: bitter, are slightly cold.Return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.Record in " herbal classic ": main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat.
Rhizoma Smilacis Glabrae: be the dry rhizome of liliaceous plant smilacis glabra Smilax glabra Roxb..Nature and flavor: sweet, light are flat.Return liver, stomach warp.Effect: dehumidifying, removing toxic substances, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.Record in " book on Chinese herbal medicine just ": treat carbuncle, sore throat, except the whole body cold-damp, malignant boil.
Herba Euphorbiae Humifusae: be the dry herb of euphorbia plant Radix seu Caulis Parthenocissi tricuspidatae Euphorbia humifusa Willd. or Herba Euphorbiae supinae Euphorbia maculata L..Nature and flavor: pungent are flat.Return liver, large intestine channel.Effect: heat-clearing and toxic substances removing, cooling blood for hemostasis.For dysentery, have loose bowels, hemoptysis, hematuria, has blood in stool, metrorrhagia, furuncle carbuncle.Record in " detailed outline ": main carbuncle malignant boil, it is hemorrhage that Jin Ren flutters damage, dysentery, hematochezia, metrorrhagia, and the blood that can fall apart stops blooding, diuresis.
Rabdosia rubescens: for labiate is cracked rice the herb of fork.Nature and flavor: bitter in the mouth; Sweet; Cold nature.Effect: heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.Main laryngopharynx swelling and pain; Headache due to common cold; Tracheitis; Chronic hepatitis; Rheumatic arthritis; Snake bite and insect sting.
Herba Pteridis Multifidae: be the herb of Pteridaceae plant Herba Pteridis Multifidae Pteris multifida Poir..Nature and flavor: light, micro-hardship are cool.Effect: clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication; Traumatic hemorrhage is controlled in external, burn and scald.
Side's solution of the present invention is: Herba Patriniae, Herba Houttuyniae heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, Rabdosia rubescens heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, Caulis Sargentodoxae heat-clearing and toxic substances removing, Flos Lonicerae heat-clearing and toxic substances removing, wind-heat dissipating, Folium Isatidis heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, Radix Isatidis heat-clearing and toxic substances removing, Herba Violae heat-clearing and toxic substances removing, Radix Rhapontici heat-clearing and toxic substances removing, Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Rhizoma Smilacis Glabrae removing dampness and detoxicating, Herba Euphorbiae Humifusae heat-clearing and toxic substances removing, above 12 taste medicines, as monarch drug in side, have the effect of heat-clearing and toxic substances removing, loose wind pain relieving.Chinese medicine is thought, to be general evil poison point import edema caused by disorder of QI into by defending to primary disease gradually, battalion divides, blood system person and cause primary disease.So heat-clearing and toxic substances removing, loose wind pain relieving are the bases of therapeutic purulent meningitis, above 12 taste medicines are monarch drug, and first fundamentally heat-clearing and toxic substances removing, loose wind pain relieving, make disease obtain basic control.Flos Chrysanthemi Indici falls apart wind heat clearing away, suppressing the hyperactive liver improving eyesight, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Semen Persicae blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, Caulis Spatholobi blood circulation promoting and enriching, menstruction regulating and pain relieving, ministerial drug in the above five kinds of Chinese medicine side of being, effect of auxiliary monarch drug heat-clearing and toxic substances removing, loose wind pain relieving on the one hand; There is as ministerial drug effect of promoting blood circulation to restore menstrual flow, promoting the circulation of QI to relieve pain on the other hand.Herba Pteridis Multifidae clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, Spina Gleditsiae detumescence poison holding, evacuation of pus parasite killing, Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, Rhizoma Alismatis heat clearing away QI invigorating, Rhizoma Smilacis Glabrae removing dampness and detoxicating, above seven flavor medicine is as adjuvant drug, the inducement of purulent meningitis is caused from pathology treatment, effect of the heat-clearing and toxic substances removing of the monarch and his subjects two medicine, loose wind pain relieving can be promoted as adjuvant drug, the effect of body promoting blood circulation to restore menstrual flow, promoting the circulation of QI to relieve pain can be promoted by using corrigent the monarch and his subjects two medicine again.Simultaneously as the effect with activating QI dampness.The all medicines of this side share, and the monarch and his subjects pull together, and minister assistant is auxiliary altogether, have effect of heat-clearing and toxic substances removing, loose wind pain relieving, promoting blood circulation to restore menstrual flow, promoting the circulation of QI to remove dampness, can effective therapeutic purulent meningitis.
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, be rich in aminoacid and have more than 17 kinds, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus.Above nutritional labeling is all needed by human material, effectively can strengthen body immunity.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Herba Houttuyniae 22-26g, Herba Patriniae 18-22g, Rabdosia rubescens 10-14g, Caulis Sargentodoxae 22-26g, Flos Lonicerae 13-17g, Folium Isatidis 13-17g, Radix Isatidis 13-17g, Herba Violae 10-14g, Flos Chrysanthemi Indici 7-11g, Rhizoma Chuanxiong 16-20g, Herba Pteridis Multifidae 13-17g, Semen Persicae 10-14g, Flos Carthami 7-11g, Radix Astragali 28-32g, Ramulus Cinnamomi 16-20g, Spina Gleditsiae 22-26g, Caulis Spatholobi 28-32g, Poria 13-17g, Rhizoma Alismatis 13-17g, Radix Rhapontici 13-17g, Fructus Forsythiae 13-17g, Rhizoma Smilacis Glabrae 22-26g, Herba Euphorbiae Humifusae 13-17g.
Wherein be preferably: Herba Houttuyniae 24g, Herba Patriniae 20g, Rabdosia rubescens 12g, Caulis Sargentodoxae 24g, Flos Lonicerae 15g, Folium Isatidis 15g, Radix Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Chuanxiong 18g, Herba Pteridis Multifidae 15g, Semen Persicae 12g, Flos Carthami 9g, Radix Astragali 30g, Ramulus Cinnamomi 18g, Spina Gleditsiae 24g, Caulis Spatholobi 30g, Poria 15g, Rhizoma Alismatis 15g, Radix Rhapontici 15g, Fructus Forsythiae 15g, Rhizoma Smilacis Glabrae 24g, Herba Euphorbiae Humifusae 15g.
A kind of preparation method of the Chinese medicine preparation for purulent meningitis is as follows:
Step one: by weight of the present invention, gets Semen Persicae according to Chinese medicine hot pillar method parch Semen Persicae, cooling, pulverizes, and crosses 200 mesh sieves, for subsequent use;
Step 2: by weight proportion of the present invention, get Radix Isatidis, the Radix Astragali, Ramulus Cinnamomi, Spina Gleditsiae, Caulis Spatholobi, Rhizoma Alismatis, Radix Rhapontici, rhizoma smilacis glabrae medicinal material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Herba Houttuyniae, Herba Patriniae, Rabdosia rubescens, Caulis Sargentodoxae, Flos Lonicerae, Folium Isatidis, Herba Violae, Flos Chrysanthemi Indici, Rhizoma Chuanxiong, Herba Pteridis Multifidae, Flos Carthami, Poria, Herba Euphorbiae Humifusae and respectively with the Fructus Forsythiae that bundle ties, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use;
Step 3: combining step two gained filtrate and step one gained powder, mixing, stirs evenly, both the decoction of therapeutic purulent meningitis of the present invention.
Using method of the present invention: get decoction, takes in one hour after meal, every day three times.
Medicine of the present invention has the effect of heat-clearing and toxic substances removing, loose wind pain relieving, promoting blood circulation to restore menstrual flow, promoting the circulation of QI to remove dampness, and good analgesic effect, cheap, have no side effect, easy to use, the mode that this Chinese medicine preparation adopts is treated and can be reduced the injury of Western medicine to patient body, alleviate the slight illness of patient, according to clinical 60 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 83.3%, two the total effective rate course for the treatment of 93.4%.
Detailed description of the invention
Embodiment one: Herba Houttuyniae 24g, Herba Patriniae 20g, Rabdosia rubescens 12g, Caulis Sargentodoxae 24g, Flos Lonicerae 15g, Folium Isatidis 15g, Radix Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Chuanxiong 18g, Herba Pteridis Multifidae 15g, Semen Persicae 12g, Flos Carthami 9g, Radix Astragali 30g, Ramulus Cinnamomi 18g, Spina Gleditsiae 24g, Caulis Spatholobi 30g, Poria 15g, Rhizoma Alismatis 15g, Radix Rhapontici 15g, Fructus Forsythiae 15g, Rhizoma Smilacis Glabrae 24g, Herba Euphorbiae Humifusae 15g.
Embodiment two: Herba Houttuyniae 23g, Herba Patriniae 21g, Rabdosia rubescens 11g, Caulis Sargentodoxae 22g, Flos Lonicerae 15g, Folium Isatidis 15g, Radix Isatidis 14g, Herba Violae 11g, Flos Chrysanthemi Indici 8g, Rhizoma Chuanxiong 18g, Herba Pteridis Multifidae 15g, Semen Persicae 12g, Flos Carthami 8g, Radix Astragali 31g, Ramulus Cinnamomi 18g, Spina Gleditsiae 23g, Caulis Spatholobi 30g, Poria 14g, Rhizoma Alismatis 15g, Radix Rhapontici 14g, Fructus Forsythiae 14g, Rhizoma Smilacis Glabrae 23g, Herba Euphorbiae Humifusae 15g.
Embodiment three: Herba Houttuyniae 25g, Herba Patriniae 21g, Rabdosia rubescens 11g, Caulis Sargentodoxae 21g, Flos Lonicerae 15g, Folium Isatidis 15g, Radix Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 8g, Rhizoma Chuanxiong 18g, Herba Pteridis Multifidae 15g, Semen Persicae 11g, Flos Carthami 8g, Radix Astragali 31g, Ramulus Cinnamomi 17g, Spina Gleditsiae 24g, Caulis Spatholobi 30g, Poria 14g, Rhizoma Alismatis 14g, Radix Rhapontici 14g, Fructus Forsythiae 14g, Rhizoma Smilacis Glabrae 23g, Herba Euphorbiae Humifusae 13g.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 60 example for medical treatment, patient is divided at random observation group and each 30 examples of matched group, wherein male 40 example, women 20 example, M-F 2:1, max age 3 years old, minimal ages 70 years old, the course of disease several days to several years is not etc.Every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, diagnostic criteria
1, onset is anxious, often has upper sense symptom before disease., there are headache, Nausea and vomiting acute stage, body temperature up to 39 DEG C ~ 40 DEG C, spirit is withered Mi or excitement, delirium, mental disorder, general malaise, even exhaustion.Can occur time heavier that the craniums such as the vomiting of severe headache, spurting and moderate pulse press high symptom.Disturbance of consciousness can be there is rapidly in anxious severe one.
2, meningeal irritation sign: neck is strong, kernig sign and the brudzinski's sign positive.
3, cranial nerve is levied: comprise visual deterioration, ocular motility disorder, facial paralysis, audition and labyrinthine dysfunction.
4, focal or Generalized seizures.
5, cerebrospinal fluid is muddy, and cell number is higher, can reach 1 × 109/L(1000/mm3) more than, more than 90% is neutrophilic granulocyte, and albumen increases, sugared content reduces, and antibacterial culturing and smear are often positive.
Three, Therapeutic Method:
1, observation group is according to Medications Example one of the present invention, and weighting raw materials, by the treatment of invention implementation method, is got decoction, taken in one hour after meal, every day three times.It within 7 days, is a course for the treatment of.
2, matched group adopts the treatment of conventional western medicine Ro-13-9904, within 7 days, is a course for the treatment of.
Four, efficacy assessment standard:
1, cure: body temperature is steady, sings and symptoms disappears, no sequel; Blood leukocytes sum, classification and cerebrospinal fluid are conventional normal, cultivate negative.
2, take a turn for the better: symptom, sign disappear or take a turn for the better; Blood leukocytes sum and classification are normally; Cerebrospinal fluid is conventional normal or take a turn for the better, and cultivates negative.
3, invalid: more than treatment one-period, symptom is not all felt any better, and even sb.'s illness took a turn for the worse for person.
Five, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of
Wherein: total effective rate=cure rate+improvement rate
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness on therapeutic purulent meningitis, effectively can improve the cure rate for the treatment of, Be very effective, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.
Model case and curative effect:
Case one, patient Wang, female, 4 years old, people from Qingdao City, came here and goes to a doctor on January 20th, 2010.Symptoms is heating, pharyngalgia, cough, skin furuncle and phyma, and patient occurs agitation, cries and screams, loss of appetite, occurs typical meningeal irritation sign---stiffness of the neck, kernig sign, brudzinski's sign are positive, and bregma protuberance, sutura split, and are diagnosed as purulent meningitis.Through western medical treatment pain relief, but do not cure.Then here treatment, adopts made preparation in the embodiment of the present invention one, and selected preparation method, and symptom goes down, and medication is after 5 days, and recover good, continue medication 6 days, thoroughly cure, Effect of follow-up visit by telephone does not recur half a year.
Case two, patient Lee, female, 3 years old, people from Linyi, Shandong.Come here on May 14th, 2010 to go to a doctor, symptom is as follows after diagnosing: there are headache, Nausea and vomiting acute stage, body temperature is up to 0 DEG C, spirit is withered Mi, delirium, mental disorder, general malaise, neck is strong, kernig sign and the brudzinski's sign positive, visual deterioration, ocular motility disorder, facial paralysis, cerebrospinal fluid is muddy, cell number is higher, can 1 × 109/L(1000/mm3 be reached) more than, more than 90% is neutrophilic granulocyte, and albumen increases, sugared content reduces, antibacterial culturing and smear are often positive, are diagnosed as purulent meningitis.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, medication is after 7 days, and recover good, continue medication 5 days, thoroughly cure, Effect of follow-up visit by telephone does not recur half a year.
Claims (4)
1. the Chinese medicine preparation for purulent meningitis, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Herba Houttuyniae 22-26g, Herba Patriniae 18-22g, Rabdosia rubescens 10-14g, Caulis Sargentodoxae 22-26g, Flos Lonicerae 13-17g, Folium Isatidis 13-17g, Radix Isatidis 13-17g, Herba Violae 10-14g, Flos Chrysanthemi Indici 7-11g, Rhizoma Chuanxiong 16-20g, Herba Pteridis Multifidae 13-17g, Semen Persicae 10-14g, Flos Carthami 7-11g, Radix Astragali 28-32g, Ramulus Cinnamomi 16-20g, Spina Gleditsiae 22-26g, Caulis Spatholobi 28-32g, Poria 13-17g, Rhizoma Alismatis 13-17g, Radix Rhapontici 13-17g, Fructus Forsythiae 13-17g, Rhizoma Smilacis Glabrae 22-26g, Herba Euphorbiae Humifusae 13-17g.
2. the Chinese medicine preparation for purulent meningitis according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Herba Houttuyniae 24g, Herba Patriniae 20g, Rabdosia rubescens 12g, Caulis Sargentodoxae 24g, Flos Lonicerae 15g, Folium Isatidis 15g, Radix Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Chuanxiong 18g, Herba Pteridis Multifidae 15g, Semen Persicae 12g, Flos Carthami 9g, Radix Astragali 30g, Ramulus Cinnamomi 18g, Spina Gleditsiae 24g, Caulis Spatholobi 30g, Poria 15g, Rhizoma Alismatis 15g, Radix Rhapontici 15g, Fructus Forsythiae 15g, Rhizoma Smilacis Glabrae 24g, Herba Euphorbiae Humifusae 15g.
3. the Chinese medicine preparation for purulent meningitis according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.
4. for a preparation method for the Chinese medicine preparation of purulent meningitis, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, gets Semen Persicae according to Chinese medicine hot pillar method parch Semen Persicae, cooling, pulverizes, and crosses 200 mesh sieves, for subsequent use;
Step 2: by weight proportion of the present invention, get Radix Isatidis, the Radix Astragali, Ramulus Cinnamomi, Spina Gleditsiae, Caulis Spatholobi, Rhizoma Alismatis, Radix Rhapontici, rhizoma smilacis glabrae medicinal material be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Herba Houttuyniae, Herba Patriniae, Rabdosia rubescens, Caulis Sargentodoxae, Flos Lonicerae, Folium Isatidis, Herba Violae, Flos Chrysanthemi Indici, Rhizoma Chuanxiong, Herba Pteridis Multifidae, Flos Carthami, Poria, Herba Euphorbiae Humifusae and respectively with the Fructus Forsythiae that bundle ties, intense fire infusion 10-20 minute, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use; Step 3: combining step two gained filtrate and step one gained powder, mixing, stirs evenly, both the decoction of therapeutic purulent meningitis of the present invention.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040039066A1 (en) * | 2002-02-13 | 2004-02-26 | Roberto Crea | Method and composition for treatment of inflammation and AIDS-associated neurological disorders |
| CN103830469A (en) * | 2014-03-25 | 2014-06-04 | 崔新明 | Chinese medicinal composition for treating purulent meningitis and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040039066A1 (en) * | 2002-02-13 | 2004-02-26 | Roberto Crea | Method and composition for treatment of inflammation and AIDS-associated neurological disorders |
| CN103830469A (en) * | 2014-03-25 | 2014-06-04 | 崔新明 | Chinese medicinal composition for treating purulent meningitis and application thereof |
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| Title |
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| 万力生等: "《全科医师临床医嘱速查》", 31 August 2011, 人民军医出版社 * |
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Application publication date: 20151021 |