CN105078422B - Method and apparatus for monitoring cardiopulmonary resuscitation compression interruption time - Google Patents
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Abstract
Description
技术领域technical field
本申请涉及本申请涉及医疗领域,尤其涉及一种监测心肺复苏按压中断时间的方法、装置和医疗设备。The present application relates to the medical field, and in particular, to a method, a device and a medical device for monitoring the interruption time of cardiopulmonary resuscitation.
背景技术Background technique
心血管疾病已成为人类发病和死亡的最主要病因,每年导致全球约17,000,000人死亡,其中许多表现为心源性猝死。心源性猝死已经成为威胁人类生命健康的重要杀手,而针对这一情况最有效和直接的医疗手段就是心肺复苏(CPR)。CPR通过增加胸内压(胸泵机制)或直接挤压心脏(心泵机制)产生血流,使氧气输送到大脑和其他生命器官,从而建立临时性的人工循环。Cardiovascular disease has become the leading cause of human morbidity and mortality, resulting in approximately 17 million deaths worldwide each year, many of which manifest as sudden cardiac death. Sudden cardiac death has become an important killer threatening human life and health, and the most effective and direct medical method for this situation is cardiopulmonary resuscitation (CPR). CPR creates a temporary artificial circulation by increasing intrathoracic pressure (thoracic pumping mechanism) or directly squeezing the heart (cardiac pumping mechanism) to generate blood flow to deliver oxygen to the brain and other vital organs.
在病人没有自主循环恢复的状态下,应进行高质量的胸外按压,并尽可能地减少中断。2013年美国心脏病学会推荐胸外按压时间占总抢救时间不应低于80%。在胸外按压过程中由于气管插管、更换按压者、电除颤等操作,常导致按压中断。过多的中断胸外按压,会导致冠脉灌注压下降,从而导致自主循环恢复率下降,即便自主循环恢复也将降低远期神经功能学预后。目前尚无一项简便易行的监测手段来发现并提醒施救者按压中断情况,使心肺复苏质量下降,难以达到理想的抢救效果。对于心跳骤停的病人在进行胸外按压过程中,血氧监测会显示出按压所引起的血流脉冲波形,若按压中断血流脉冲波形即刻消失。常规血氧监测一般只能显示脉搏波波形,需通过人眼观察脉搏波波形来进行判断,无法直接对按压中断时间进行预警。In the absence of recovery of spontaneous circulation, high-quality chest compressions should be performed with minimal interruptions. In 2013, the American College of Cardiology recommended that chest compression time should not be less than 80% of the total rescue time. In the process of chest compressions, due to endotracheal intubation, replacement of the compressor, electrical defibrillation and other operations, the compression is often interrupted. Excessive interruption of chest compressions will lead to a decrease in coronary perfusion pressure, which will lead to a decrease in the rate of recovery of spontaneous circulation, and even recovery of spontaneous circulation will reduce long-term neurological outcomes. At present, there is no simple and easy monitoring method to detect and remind the rescuer of the interruption of compression, which reduces the quality of cardiopulmonary resuscitation and makes it difficult to achieve the ideal rescue effect. For patients with cardiac arrest during chest compression, blood oxygen monitoring will display the blood flow pulse waveform caused by the compression. If the compression is interrupted, the blood flow pulse waveform disappears immediately. Conventional blood oxygen monitoring generally can only display the pulse wave waveform, which needs to be judged by observing the pulse wave waveform with the human eye, and cannot directly give an early warning of the interruption time of pressing.
发明内容SUMMARY OF THE INVENTION
本申请提供一种脉搏波处理方法、装置和医疗设备。The present application provides a pulse wave processing method, device and medical equipment.
根据本申请的第一方面,本申请提供一种监测心肺复苏按压中断时间的方法,包括:According to a first aspect of the present application, the present application provides a method for monitoring the interruption time of cardiopulmonary resuscitation compressions, comprising:
对被测信号进行处理,所述被测信号反映被测者的实时脉搏特性;Process the measured signal, the measured signal reflects the real-time pulse characteristics of the measured person;
根据处理结果进行脉搏波识别;Pulse wave recognition is performed according to the processing result;
根据识别结果对脉搏波消停的期间进行统计;According to the recognition result, the period of pulse wave extinction is counted;
输出统计信息。Output statistics.
根据本申请的第二方面,本申请提供一种监测心肺复苏按压中断时间的处理装置,包括:According to a second aspect of the present application, the present application provides a processing device for monitoring the interruption time of CPR compressions, including:
模数转换单元,用于对被测信号进行处理,所述被测信号反映被测者的实时脉搏特性;an analog-to-digital conversion unit for processing the measured signal, the measured signal reflecting the real-time pulse characteristics of the measured person;
数字信号处理单元,用于根据处理结果进行脉搏波识别,并根据识别结果对脉搏波消停的期间进行统计;The digital signal processing unit is used to identify the pulse wave according to the processing result, and perform statistics on the period of pulse wave extinction according to the identification result;
输出单元,用于输出统计信息。Output unit for outputting statistics.
根据本申请的第三方面,本申请提供一种医疗设备,包括:According to a third aspect of the present application, the present application provides a medical device, comprising:
光发射接收器,其包含发光管和接收管,所述发光管发射用于透过人体组织的至少一路光信号,所述接收管接收透过人体组织的至少一路光信号,并转为至少一路电信号;A light-emitting receiver, which includes a light-emitting tube and a receiving tube, the light-emitting tube emits at least one light signal for passing through human tissue, the receiving tube receives at least one light signal passing through the human tissue, and converts it into at least one light signal electric signal;
数字处理器,用于将所述电信号转换为数字信号,以及对所述数字信号进行处理,根据处理结果进行脉搏波识别,并对脉搏波消停的期间进行统计;a digital processor, configured to convert the electrical signal into a digital signal, process the digital signal, identify the pulse wave according to the processing result, and count the period during which the pulse wave stops;
输出模块,用于输出统计信息。Output module for outputting statistics.
由于采用了以上技术方案,使本申请具备的有益效果在于:Due to the adoption of the above technical solutions, the beneficial effects of the present application are:
⑴在本申请的具体实施方式中,由于通过对脉搏波的识别结果对脉搏波消停的期间进行统计,并输出统计信息,使得医护人员可直接获取统计信息,相对于现有技术中,通过人眼观察脉搏波波形来对脉搏波进行判断,本申请可直观地显示脉搏波消停的期间的信息,可提醒医生注意避免潜在危险,以利于提高心肺复苏成功率。(1) In the specific embodiment of the present application, since the period of pulse wave extinction is counted by the recognition result of the pulse wave, and the statistical information is output, the medical staff can directly obtain the statistical information. The pulse wave can be judged by observing the pulse wave waveform with the eyes. The application can intuitively display the information of the period of the pulse wave extinction, and can remind the doctor to avoid potential dangers, so as to improve the success rate of cardiopulmonary resuscitation.
⑵在本申请的具体实施方式中,由于输出的统计信息包括脉搏波消停时间的时长,可使医生监控停止按压的时间,可避免因停止按压的时间超过规定时间而使病人产生危险。(2) In the specific embodiment of the present application, since the output statistical information includes the duration of the pulse wave extinction time, the doctor can monitor the time of stopping the compression, which can prevent the patient from being in danger because the time of stopping the compression exceeds the specified time.
⑶在本申请的具体实施方式中,由于输出的统计信息包括统计脉搏波消停时间的总占时比,可直观地提醒医生,使医生避免因主观因素或疏忽使胸外按压时间比降低而引起的危险。(3) In the specific embodiment of the present application, since the output statistical information includes the total time ratio of the statistical pulse wave extinction time, the doctor can be intuitively reminded, so that the doctor can avoid the reduction of the chest compression time ratio due to subjective factors or negligence. danger.
附图说明Description of drawings
图1为申请方法的在一种实施方式中的流程图;Fig. 1 is the flow chart in one embodiment of the application method;
图2为一种实施例中的人工/机械按压状态变化的示意图;FIG. 2 is a schematic diagram of a manual/mechanical pressing state change in an embodiment;
图3为本申请装置的在一种实施方式中的功能模块示意图。FIG. 3 is a schematic diagram of functional modules of the apparatus of the present application in an embodiment.
具体实施方式Detailed ways
下面通过具体实施方式结合附图对本申请作进一步详细说明。The present application will be further described in detail below through specific embodiments in conjunction with the accompanying drawings.
实施例一:Example 1:
如图1所示,本申请的脉搏波处理方法,其一种实施方式,包括以下步骤:As shown in FIG. 1 , the pulse wave processing method of the present application, an embodiment thereof, includes the following steps:
步骤102:对被测信号进行处理,被测信号反映被测者的实时脉搏特性。其中对被测信号进行处理,具体包括:Step 102: Process the measured signal, and the measured signal reflects the real-time pulse characteristics of the measured person. Among them, the signal under test is processed, including:
从被测信号中识别出波动成分和恒定成分;Identify fluctuating and constant components from the measured signal;
基于波动成分生成脉搏波。Pulse waves are generated based on fluctuation components.
本申请可建立滑动时间窗,在滑动时间窗内显示脉搏波。In this application, a sliding time window can be established, and the pulse wave can be displayed in the sliding time window.
步骤104:根据处理结果进行脉搏波识别。Step 104: Perform pulse wave identification according to the processing result.
在病人没有自主循环恢复的状态下,应进行高质量的胸外按压,并尽可能的减少中断。人工按压过程中进行气管插管或更换按压者等因素,常常导致按压中断。最新心肺复苏指南提出胸外按压时间比应在80%以上,胸外按压中断不能超过10s,过长时间的中断按压,将显著降低自主循环恢复率。而在实际临床抢救情况下,并不能监测中断按压时间,也不能对医疗人员进行及时提醒,常常导致过长时间的按压中断,胸外按压时间比例下降,不利于病人自主循环的恢复。In the absence of recovery of spontaneous circulation, high-quality chest compressions should be performed with minimal interruptions. Factors such as tracheal intubation or replacement of the compressor during manual compression often lead to interruption of compression. The latest cardiopulmonary resuscitation guidelines propose that the chest compression time ratio should be more than 80%, and the interruption of chest compressions should not exceed 10s. Interrupting compressions for too long will significantly reduce the recovery rate of spontaneous circulation. However, in the actual clinical rescue situation, it is not possible to monitor the interruption time of compression, nor to remind medical staff in time, which often leads to interruption of compression for a long time, and the proportion of chest compression time decreases, which is not conducive to the recovery of patients' spontaneous circulation.
基于病人无自主循环的前提,人工按压挤压心脏,会产生心脏的搏动,在手指末梢就会形成血液循环。而这种按压一旦停止,血液循环就会消失。在血氧系统表现为:按压存在,有脉搏波信号,按压停止,脉搏波消失。因此,可通过脉搏波的变化,识别脉搏波的人工/机械按压状态。本文所描述的人工/机械按压状态包括按压持续状态和按压间歇状态。当人工/机械按压状态为按压持续状态时,脉搏波持续;当人工/机械按压状态为按压间歇状态时,脉搏波消停。Based on the premise that the patient has no spontaneous circulation, manual pressing and squeezing of the heart will generate a heartbeat, and blood circulation will be formed at the fingertips. And once this pressing is stopped, the blood circulation will disappear. In the blood oxygen system, the pressure is present, there is a pulse wave signal, the pressure is stopped, and the pulse wave disappears. Therefore, the artificial/mechanical compression state of the pulse wave can be recognized by the change of the pulse wave. The manual/mechanical compression states described herein include the compression continuous state and the compression intermittent state. When the manual/mechanical pressing state is the pressing continuous state, the pulse wave continues; when the manual/mechanical pressing state is the pressing intermittent state, the pulse wave stops.
脉搏波的识别可以通过单次脉搏的幅度(Amplitude)和宽度(Width)来识别。幅度即为AC交流分量,宽度是单次脉搏频率的采样点数的映射。采样点数与频率、脉搏的映射关系为:The identification of the pulse wave can be identified by the amplitude (Amplitude) and width (Width) of a single pulse. The amplitude is the AC component, and the width is the mapping of the sampling points of the single pulse frequency. The mapping relationship between the number of sampling points and frequency and pulse is:
PulseRate=60*fHz=60*SampleRate/WidthPulseRate=60*f Hz =60*SampleRate/Width
PulseRate为脉搏每分钟次数(单位:次/每分),fHz为单次脉搏频率,SampleRate为血氧信号采样率,Width为单次脉搏的脉宽,即采样点数。时域面积指标也是基于单次脉搏的宽度来实现的。PulseRate is the number of pulses per minute (unit: times/minute), f Hz is the single pulse frequency, SampleRate is the sampling rate of the blood oxygen signal, and Width is the pulse width of a single pulse, that is, the number of sampling points. The time domain area indicator is also based on the width of a single pulse.
传统方法仅提取单次脉搏波的幅度和宽度信息,就可用于判断是否为一次完整脉搏波。在临床按压抢救的恶劣环境下,干扰可能会增加脉搏波识别的难度,仅依靠幅度和宽度信息,可能会出现误识别现象。The traditional method only extracts the amplitude and width information of a single pulse wave, which can be used to judge whether it is a complete pulse wave. In the harsh environment of clinical compression rescue, interference may increase the difficulty of pulse wave identification, and only relying on amplitude and width information may cause misidentification.
在一种实施方式中,进行脉搏波识别包括:In one embodiment, performing pulse wave identification includes:
取多个单次脉搏波,通过多个单次脉搏波的变化,识别脉搏波消停的期间。Take multiple single pulse waves, and identify the period during which the pulse wave stops through the changes of the multiple single pulse waves.
在一种实施方式中,可以至少取3个连续的单次脉搏波,通过单次脉搏波面积值的变化或单次脉搏波波形的变化,识别脉搏波消停的期间。In one embodiment, at least three consecutive single pulse waves can be taken, and the period of pulse wave extinction can be identified by the change in the area value of the single pulse wave or the change in the waveform of the single pulse wave.
为提升脉搏波/非脉搏波的识别正确率,可以采用更多的特征信息辅助识别。在一种实施方式中,通过连续多个(如大于等于3个)单次脉搏波的面积值的波动变化或连续多个(如大于等于3个)单次脉搏波的波形形态的相关性等方法,通过附加的这些方法,可以大幅度提高脉搏和无脉搏状态的识别率,降低临床干扰对参数测量的影响。In order to improve the recognition accuracy of pulse wave/non-pulse wave, more feature information can be used to assist the recognition. In one embodiment, through the fluctuation of the area value of a plurality of consecutive (such as greater than or equal to 3) single pulse waves or the correlation of the waveform shapes of a plurality of consecutive (such as greater than or equal to 3) single pulse waves, etc. By adding these methods, the recognition rate of pulse and no pulse state can be greatly improved, and the influence of clinical interference on parameter measurement can be reduced.
步骤106:根据识别结果对脉搏波消停的期间进行统计;Step 106: according to the recognition result, perform statistics on the period of pulse wave extinction;
在本申请中,脉搏波消停的期间为人工/机械按压间歇期。In the present application, the period during which the pulse wave ceases is the manual/mechanical compression interval.
在一种实施方式中,根据识别结果对脉搏波消停期间进行统计,包括:统计脉搏波消停时间的时长。In an implementation manner, according to the identification result, the pulse wave extinction period is counted, including: counting the duration of the pulse wave extinction time.
在另一种实施方式中,根据识别结果对脉搏波消停期间进行统计,还包括:In another implementation manner, according to the identification result, statistics are performed on the period of pulse wave extinction, further comprising:
统计脉搏波消停时间的总占时比,脉搏波消停时间的总占时比为脉搏波消停期间的累积时长与心肺复苏操作时长的比值。The total time ratio of pulse wave extinction time is counted, which is the ratio of the cumulative duration of the pulse wave extinction period to the CPR operation duration.
在另一种实施方式中,根据识别结果对脉搏波消停期间进行统计,还包括:In another implementation manner, according to the identification result, statistics are performed on the period of pulse wave extinction, further comprising:
预先设置第一阈值和第二阈值;Preset the first threshold and the second threshold;
当脉搏波消停期间的时长大于第一阈值时,输出报警提示信息;When the duration of the pulse wave extinction period is greater than the first threshold, output alarm prompt information;
和/或当脉搏波消停时间的总占时比大于第二阈值时,输出报警提示信息。And/or when the total occupancy ratio of the pulse wave extinction time is greater than the second threshold, output alarm prompt information.
本申请可通过以下方式实现总计时:1.默认病人夹戴上探头时,即启动计时,探头空置不接病人时自动清零(探头是采集病人生理信号的媒介);2.设置启动和停止按钮,在使用过程中,由医生、护士操作实现,应用时,点击“启动”,即开始总时间计时,点击“停止”,即停止总时间计时统计。The application can realize the total time in the following ways: 1. By default, when the patient clip puts on the probe, the timer is started, and the probe is automatically cleared when the probe is not connected to the patient (the probe is the medium for collecting the patient's physiological signals); 2. Set start and stop The button is operated by doctors and nurses during use. When applying, click "Start" to start the total time counting, and click "Stop" to stop the total time counting.
在人工/机械按压间歇期结束,人工/机械按压状态转为人工/机械按压持续状态,即再次出现按压波形时,则不计时。At the end of the manual/mechanical compression interval, the manual/mechanical compression state changes to the manual/mechanical compression continuous state, that is, when the compression waveform appears again, the timing will not be counted.
在一种实施方式中,脉搏波消停时间总占时比,具体通过以下公式进行计算:In an embodiment, the total time-to-time ratio of the pulse wave extinction time is specifically calculated by the following formula:
其中,为人工/机械按压过程的采样点累积统计;为人工/机械按压过程中出现人工/机械间歇期的采样点数据累积统计;其中p=1,2,3,……P,p指第p次人工/机械间歇期;P指在N点长度的人工/机械按压过程中发生的人工/机械间歇期的总次数;q=1,2,3,……Q,q为第p次CPR间歇期中的第q点,Q指第p次人工/机械间歇期所持续的总点数。in, Cumulative statistics for the sampling points of the manual/mechanical compression process; It is the cumulative statistics of the sampling point data of the manual/mechanical interval during the manual/mechanical compression process; where p=1,2,3,...P, p refers to the p-th manual/mechanical interval; P refers to the length at point N The total number of manual/mechanical intervals occurred during the manual/mechanical compression; q=1,2,3,...Q, q is the qth point in the pth CPR interval, and Q refers to the pth manual/mechanical interval. The total number of points the mechanical interval lasts.
步骤108:输出统计信息。本申请可在显示屏上显示统计信息。Step 108: Output statistical information. This application can display statistical information on the display.
在单次脉搏波信号识别准确的基础上,本申请的脉搏波处理方法,其另一种实施方式,包括以下步骤:On the basis that the single pulse wave signal is accurately identified, the pulse wave processing method of the present application, another implementation manner thereof, includes the following steps:
步骤202:建立滑动时间窗,综合考察窗内的脉搏波状态,滑动时间窗的时间可以根据实际情况进行设置,本申请默认设置为10S;如图2中D(即Slip Window)所示。Step 202: Establish a sliding time window, comprehensively investigate the pulse wave state in the window, and the time of the sliding time window can be set according to the actual situation, and the default setting of this application is 10S; as shown in D (ie, Slip Window) in FIG. 2 .
步骤204:判断滑动时间窗内脉搏波状态,并根据识别状态进行其他新的操作。从响应速度和稳定性角度考虑,本申请默认衡量>=3个脉搏波特征,并以此决策是否为人工/机械按压持续状态或人工/机械按压间歇状态。如图所示,在A(即CPR Duration 1)状态和C(即CPR Duration 2)状态中,通过>=3个脉搏波特征分析,识别为人工/机械按压脉搏波,则不会启动脉搏波消停时间的计时统计。Step 204: Determine the pulse wave state in the sliding time window, and perform other new operations according to the recognized state. From the perspective of response speed and stability, this application measures >=3 pulse wave characteristics by default, and decides whether it is in the continuous state of manual/mechanical compression or the intermittent state of manual/mechanical compression. As shown in the figure, in the A (ie CPR Duration 1) state and the C (ie CPR Duration 2) state, through the analysis of >= 3 pulse wave characteristics, if it is identified as a manual/mechanical compression pulse wave, the pulse wave will not be activated. Timing statistics for dead time.
步骤206:在采样信号进入无脉搏状态时,脉搏波消停时间计时就会启动。时间计时按照采样点数累积,每一个周期采样率为1S。最终表现为人工/机械按压间歇期秒时间计时。如图中B(即Interval Without CPR)段中,标号“1”位置所示。从该位置启动CPR间歇时间计时,并将该信息提供给客户端。在人工/机械按压间歇时间结束,即再次出现按压波形时,CPR间歇时间计时显示功能停止,并清零复位。Step 206: When the sampling signal enters a pulseless state, the pulse wave extinction time timer is started. The time count is accumulated according to the number of sampling points, and the sampling rate of each cycle is 1S. The final performance is the timing of seconds between manual/mechanical compression intervals. In the B (ie Interval Without CPR) section in the figure, the position of the label "1" is shown. Start the CPR interval timer from this location and provide this information to the client. At the end of the manual/mechanical compression interval, that is, when the compression waveform appears again, the CPR interval timer display function stops and is reset to zero.
在实际应用中,如上所述,基于衡量>=3个脉搏波特征的原则,在进入无脉搏状态时,也会继续衡量>=3个脉搏波长度的数据是否为无脉搏数据,以此识别结果为依据,判断是否进入人工/机械按压间歇期。这就意味着人工/机械按压间歇时间计时显示功能存在滞后特征。同理,在从人工/机械按压间歇期进入人工/机械按压阶段时,受到脉搏波识别判断的影响,人工/机械按压间歇时间计时显示功能会继续存在一段时间,在识别出按压脉搏波后,计时显示功能才会关闭并清零复位。如图2所示,统计人工/机械按压时间的计时显示不会在如图标号“1”的位置出现,而是会出现在标号“2”的位置。同理,在进入C阶段,CPR间歇时间计时显示会持续>=3个脉搏的时间才会关闭并清零复位。In practical applications, as mentioned above, based on the principle of measuring >=3 pulse wave characteristics, when entering the pulseless state, it will continue to measure whether the data with >=3 pulse wave lengths is pulseless data, so as to identify Based on the results, determine whether to enter the manual/mechanical compression interval. This means that there is a hysteresis characteristic of the manual/mechanical compression interval time timing display function. In the same way, when entering the manual/mechanical compression stage from the manual/mechanical compression interval, affected by the pulse wave recognition and judgment, the manual/mechanical compression interval time timing display function will continue to exist for a period of time. The timing display function will be turned off and reset to zero. As shown in FIG. 2 , the timing display for counting the time of manual/mechanical pressing will not appear at the position marked “1”, but will appear at the position marked “2”. Similarly, when entering the C stage, the CPR interval timer display will last for >= 3 pulses before it is turned off and reset to zero.
人工/机械按压间歇时间计时显示功能的滞后特征,取决于所识别脉搏波的宽度,即脉搏频率。脉搏频率越高,识别所需的时间就越短,反之识别所需时间就越长。本申请默认分析>=3个脉搏波,且生理脉搏波范围为[20~300]BPM(对应脉搏频率为[0.33~5]Hz),由此可知,本申请在识别人工/机械按压间歇时间的响应速度为9S~0.6S;The hysteresis characteristic of the manual/mechanical compression interval timing display function depends on the width of the identified pulse wave, that is, the pulse rate. The higher the pulse rate, the shorter the recognition time, and the longer the recognition time. The default analysis of this application is >= 3 pulse waves, and the range of physiological pulse waves is [20-300] BPM (corresponding to pulse frequency [0.33-5] Hz), it can be seen that the application is in the identification of manual/mechanical compression interval time The response speed is 9S~0.6S;
3Pulse是指分析至少3个脉搏周期,[0.33Hz~5Hz]是指可识别脉宽所覆盖的频率。3Pulse refers to analyzing at least 3 pulse cycles, and [0.33Hz to 5Hz] refers to the frequency covered by the identifiable pulse width.
根据CPR指南,按压频率必须满足>=100次/分,带入上述公式,计算可知,约为1.64S即可识别按压波形状态。因此,在临床应用中,本申请中的人工/机械按压间歇时间典型响应时间为1.64S,能够满足临床中对时间特别敏感的要求,提升了医生治疗的准确度,增加病人的生存几率。According to the CPR guidelines, the compression frequency must satisfy >=100 times/min. With the above formula, the calculation shows that the compression waveform state can be recognized in about 1.64S. Therefore, in clinical application, the typical response time of the manual/mechanical compression intermittent time in this application is 1.64S, which can meet the requirement of being particularly sensitive to time in clinical practice, improve the accuracy of doctor's treatment, and increase the survival probability of patients.
步骤208:若脉搏波消停时间超过阈值时,进行报警。众多研究表明,CPR间歇时间超过10S时,对病人生理存在影响。因此本申请的脉搏波消停时间统计功能,设置10S时间阈值。如果计时时间>10S,给予报警提示信息。Step 208: If the pulse wave extinction time exceeds the threshold, an alarm is issued. Numerous studies have shown that when the CPR interval exceeds 10S, there is an impact on the patient's physiology. Therefore, the pulse wave extinction time statistics function of the present application sets a time threshold of 10S. If the timing time is more than 10S, an alarm message will be given.
步骤210:计算脉搏波消停时间总占时比,其对应CPR间歇时间总占比。根据指南要求,间歇时间占整体人工/机械按压抢救时间超过20%时,该病人肯能会出现抢救无效。本申请建立CPR间歇时间总占时比的概念,用以反映该特征。计算公式如下:Step 210: Calculate the total proportion of the pulse wave extinction time, which corresponds to the total proportion of the CPR intermittent time. According to the guidelines, when the intermittent time accounts for more than 20% of the total manual/mechanical compression rescue time, the patient may be ineffective in rescue. This application establishes the total time ratio of CPR intermittent time concept to reflect this feature. Calculated as follows:
是人工/机械按压过程的采样点累积统计;是针对人工/机械按压过程中出现CPR间歇期的采样点数据累积统计;其中p=1,2,3,……P,p指第p次发生CPR间歇期;P指在N点长度的人工/机械按压过程中发生的CPR间歇期的总次数;q=1,2,3,……Q,q指第p次CPR间歇期中的第q点,Q指第p次CPR间歇期所持续的总点数。 It is the cumulative statistics of sampling points in the manual/mechanical compression process; It is the cumulative statistics of the sampling point data for the CPR intermittent period during the manual/mechanical compression process; where p=1, 2, 3, ... P, p refers to the p-th CPR intermittent period; P refers to the artificial /Total number of CPR intervals that occurred during mechanical compression; q=1,2,3,... total points.
前述可知,采样率与时间存在对应关系,在本申请的参数中,由于分子和分母同时需要转换为时间,而两者采样率一致,因此在该公式中,采样率因子被消除,与时间实质等同,它反映了CPR间歇时间在总人工/机械按压时间的占比率。It can be seen from the foregoing that there is a corresponding relationship between the sampling rate and time. In the parameters, since the numerator and denominator need to be converted into time at the same time, and the sampling rates of the two are the same, in this formula, the sampling rate factor is eliminated, Essentially equivalent to time, it reflects the ratio of CPR interval time to total manual/mechanical compression time.
在实际应用中,参数可以实时动态更新。即在人工/机械按压抢救过程中,血氧系统每采集到一个采样点,即纳入统计中;同时根据前述判断逻辑,识别该采样点是否纳入统计中。从而,每个采样点,CPR总占时比都会刷新。本申请默认按照采样率刷新,即1S中刷新一次结果。如图“CPR Interval Ratio”所示,随着人工/机械按压启动,就会出现在显示界面中。In practical applications, Parameters can be dynamically updated in real time. That is, in the process of manual/mechanical compression rescue, every time the blood oxygen system collects a sampling point, it is included in the Statistics; at the same time, according to the aforementioned judgment logic, identify whether the sampling point is included in the Statistics. Therefore, at each sampling point, the total CPR time ratio is refreshed. The application is refreshed according to the sampling rate by default, that is, the result is refreshed once in 1S. As shown in Figure "CPR Interval Ratio", as manual/mechanical compressions are activated, will appear in the display interface.
由前述可知,在识别过程中,需要识别>=3个脉搏波周期长度才能判断是按压状态还是间歇状态,因此显示也存在时间滞后性,即图中显示的3和4位置。理论为3位置,实际为4位置。该滞后的典型时间为1.64S。It can be seen from the foregoing that in the identification process, it is necessary to identify >=3 pulse wave cycle lengths to determine whether it is a pressing state or an intermittent state, so There is also a time lag in the display, the 3 and 4 positions shown in the figure. The theory is 3 positions, the actual 4 positions. The typical time for this lag is 1.64S.
CPR间歇时间总占时比伴随人工/机械按压整个周期,直到人工/机械按压状态被复位,CPR间歇时间总占时比才会停止显示。因此,有两种机制可以复位CPR间歇时间占比率:1.在人工/机械按压过程中识别到自主心律恢复;2.外部触发复位机制(例如:监护仪的复位按钮)。The total time ratio of the CPR interval time accompanies the entire cycle of manual/mechanical compression, and the display of the total time ratio of the CPR interval time will not stop until the manual/mechanical compression state is reset. Therefore, there are two mechanisms to reset the CPR interval fraction: 1. Spontaneous rhythm recovery is recognized during manual/mechanical compressions; 2. An externally triggered reset mechanism (eg, the monitor's reset button).
步骤210:输出统计信息。可通过显示屏输出统计信息,如显示脉搏波消停时间和/或脉搏波消停时间总占时比。Step 210: Output statistical information. Statistical information can be output through the display, such as the display of the pulse wave dead time and/or the total pulse wave dead time ratio.
以上方法是基于时域脉搏波识别方法实现的特征检测。由于时域和频谱存在能量守恒特征,因此,基于频域方法也可以实现上述特征的检测识别。频域分析法取决于分析数据的长短。数据过长,反映生理信号变化趋势的特征变慢,数据过短,容易出现精度不够导致的频域分析无效。在本申请中,结合临床应用场景,设定为4S的频域数据分析长度,即每一次频域分析的数据长度为4S。为快速跟踪生理信号的变化,频域分析设定为0.5S启动一次。The above method is a feature detection based on the time-domain pulse wave recognition method. Since there are energy conservation features in the time domain and spectrum, the detection and identification of the above features can also be realized based on the frequency domain method. The frequency domain analysis method depends on the length of the analyzed data. If the data is too long, the characteristics reflecting the changing trend of physiological signals will become slower, and if the data is too short, the frequency domain analysis will be invalid due to insufficient precision. In this application, combined with the clinical application scenario, the frequency domain data analysis length is set to 4S, that is, the data length of each frequency domain analysis is 4S. In order to quickly track the changes of physiological signals, the frequency domain analysis was set to start once at 0.5S.
时域脉搏波的宽度和幅度特性,可量化为频域信号中频谱峰的幅度和宽度。因此,本申请可使用频谱峰的幅度或面积参数,衡量人工/机械按压间隙期以及人工/机械按压间歇时间占比率。在出现CPR间歇期时,随着每0.5S一次的分析,频谱峰幅度或面积会出现逐渐衰减的特征。因此可建立幅度或面积阈值线,检测4次(即2S)频谱峰幅度或面积是否均低于阈值线,如果低于阈值线,则认为是人工/机械按压间歇期,否则继续处于人工/机械按压状态。The width and amplitude characteristics of the pulse wave in the time domain can be quantified as the amplitude and width of the spectral peaks in the frequency domain signal. Therefore, the present application can use the amplitude or area parameter of the spectral peak to measure the manual/mechanical compression interval period and the ratio of the manual/mechanical compression interval time. When the CPR interval occurs, with the analysis every 0.5S, the amplitude or area of the spectral peak will appear gradually attenuated. Therefore, an amplitude or area threshold line can be established to detect whether the spectrum peak amplitude or area is lower than the threshold line for 4 times (ie 2S). pressed state.
与时域分析法相同原理,人工/机械按压间歇期存在显示时间滞后性,该滞后性取决于频域分析的间隔时间,及分析次数。本申请频域分析间隔时间为0.5S,分析4次,因此典型滞后时间为2S。CPR间歇期的最小分辨率受频域分析间隔时间约束,为0.5S。识别到人工/机械按压间歇状态时,启动人工/机械按压间歇期的时间计时显示,在识别到人工/机械按压状态时,人工/机械按压间歇期时间计时功能关闭。与时域分析法相同原理,在人工/机械按压过程中,人工/机械按压间歇时间占比率(也即上文所述的CPR间歇时间总占比)即开始计时统计。每0.5S频域分析,总计时时间就会累积,同时判断是否为CPR间歇期,并对CPR间歇期时间进行累积。CPR间歇时间占比率==CPR间歇期时间/总计时时间*100%。CPR间歇时间占比率的最小分辨率受频域分析间隔时间约束,为0.5S。其启动和复位机制与时域部分描述机制完全一致。The same principle as the time domain analysis method, there is a display time lag in the intermittent period of manual/mechanical compression, which depends on the interval time of the frequency domain analysis and the number of analyses. In this application, the frequency domain analysis interval is 0.5S, and the analysis is performed 4 times, so the typical lag time is 2S. The minimum resolution of the CPR interval is constrained by the frequency domain analysis interval, which is 0.5S. When the manual/mechanical pressing intermittent state is recognized, the time timing display of the manual/mechanical pressing intermittent period is activated. When the manual/mechanical pressing intermittent state is recognized, the manual/mechanical pressing intermittent period time timing function is turned off. The same principle as the time domain analysis method, in the process of manual/mechanical compression, the ratio of manual/mechanical compression interval time (that is, the total percentage of CPR interval time described above) starts timing statistics. Every 0.5S frequency domain analysis, the total time is accumulated, and at the same time, it is judged whether it is a CPR intermittent period, and the CPR intermittent period time is accumulated. The ratio of CPR interval time = = CPR interval time/total time period*100%. The minimum resolution of the CPR interval ratio is constrained by the frequency domain analysis interval, which is 0.5S. Its startup and reset mechanism is exactly the same as that described in the time domain section.
实施例二:Embodiment 2:
如图3所示,本申请的脉搏波处理装置,其一种实施方式,包括:模数转换单元,用于对被测信号进行处理,被测信号反映被测者的实时脉搏特性;数字信号处理单元,用于根据处理结果进行脉搏波识别,并根据识别结果对脉搏波消停的期间进行统计;输出单元,用于输出统计信息。As shown in FIG. 3 , an embodiment of the pulse wave processing device of the present application includes: an analog-to-digital conversion unit for processing a measured signal, and the measured signal reflects the real-time pulse characteristics of the measured person; a digital signal The processing unit is used to identify the pulse wave according to the processing result, and count the period of the pulse wave stop according to the recognition result; the output unit is used to output the statistical information.
模数转换单元还用于从被测信号中识别出波动成分和恒定成分,数字信号处理单元还用于基于波动成分识别出脉搏波。The analog-to-digital conversion unit is also used for identifying the fluctuation component and the constant component from the measured signal, and the digital signal processing unit is also used for identifying the pulse wave based on the fluctuation component.
在一种实施方式中,数字信号处理单元还用于统计脉搏波消停时间的时长。In one embodiment, the digital signal processing unit is further configured to count the duration of the pulse wave extinction time.
在另一种实施方式中,数字信号处理单元还用于统计脉搏波消停时间的总占时比,脉搏波消停时间的总占时比为脉搏波消停期间的累积时长与心肺复苏操作时长的比值。In another embodiment, the digital signal processing unit is further configured to count the total duty ratio of the pulse wave extinction time, and the total duration of the pulse wave extinction time is the ratio of the accumulated duration of the pulse wave extinction period to the duration of the cardiopulmonary resuscitation operation .
在另一种实施方式中,数字信号处理单元还用于预先设置第一阈值和第二阈值,并在脉搏波消停期间的时长大于第一阈值时,输出报警提示信息;和/或在脉搏波消停时间的总占时比大于第二阈值时,输出报警提示信息。In another embodiment, the digital signal processing unit is further configured to preset the first threshold and the second threshold, and output alarm prompt information when the duration of the pulse wave extinction period is greater than the first threshold; and/or when the pulse wave stops When the total time ratio of the stoppage time is greater than the second threshold, an alarm prompt message is output.
在一种实施方式中,数字信号处理单元具体通过以下公式进行计算按压间歇时间总占时比:In one embodiment, the digital signal processing unit specifically calculates the total time ratio of the pressing interval time by the following formula:
其中,为人工/机械按压过程的采样点累积统计;为人工/机械按压过程中出现人工/机械间歇期的采样点数据累积统计;其中p=1,2,3,……P,p指第p次人工/机械间歇期;P指在N点长度的人工/机械按压过程中发生的人工/机械间歇期的总次数;q=1,2,3,……Q,q为第p次CPR间歇期中的第q点,Q指第p次人工/机械间歇期所持续的总点数。in, Cumulative statistics for the sampling points of the manual/mechanical compression process; It is the cumulative statistics of the sampling point data of the manual/mechanical interval during the manual/mechanical compression process; where p=1,2,3,...P, p refers to the p-th manual/mechanical interval; P refers to the length at point N The total number of manual/mechanical intervals occurred during the manual/mechanical compression; q=1,2,3,...Q, q is the qth point in the pth CPR interval, and Q refers to the pth manual/mechanical interval. The total number of points the mechanical interval lasts.
数字信号处理单元还可用于取多个单次脉搏波,通过多个单次脉搏波的变化,识别所述脉搏波消停的期间。在一种具体实施方式中,数字信号处理单元还用于至少取3个周期的连续单次脉搏波,通过单次脉搏波面积值的变化或单次脉搏波波形的变化,识别脉搏波消停的期间。The digital signal processing unit can also be used to obtain multiple single pulse waves, and identify the period during which the pulse waves are stopped through the changes of the multiple single pulse waves. In a specific embodiment, the digital signal processing unit is further configured to take at least 3 cycles of continuous single pulse waves, and identify the pulse wave discontinuation through the change of the area value of the single pulse wave or the change of the single pulse wave waveform. period.
数字信号处理单元还可用于预先设置阈值;当按压间歇时间大于阈值时,输出报警提示信息。阈值可以根据需要进行设置,在本实施方式中,阈值可以设置为10S。The digital signal processing unit can also be used to preset a threshold value; when the pressing interval time is greater than the threshold value, output alarm prompt information. The threshold can be set as required, and in this embodiment, the threshold can be set to 10S.
实施例三:Embodiment three:
本申请的医疗设备,其一种实施方式,包括:The medical device of the present application, an embodiment thereof, includes:
光发射接收器,其包含发光管和接收管,所述发光管发射用于透过人体组织的至少一路光信号,所述接收管接收透过人体组织的至少一路光信号,并转为至少一路电信号;数字处理器,用于将所述电信号转换为数字信号,以及对所述数字信号进行处理,根据处理结果进行脉搏波识别,并对脉搏波消停的期间进行统计;输出模块,用于输出统计信息。A light-emitting receiver, which includes a light-emitting tube and a receiving tube, the light-emitting tube emits at least one light signal for passing through human tissue, the receiving tube receives at least one light signal passing through the human tissue, and converts it into at least one light signal an electrical signal; a digital processor for converting the electrical signal into a digital signal, and for processing the digital signal, identifying the pulse wave according to the processing result, and performing statistics on the period during which the pulse wave stops; an output module, which uses for output statistics.
在一种实施方式中,数字处理器通过识别数字信号反映的实时脉搏特性识别出脉搏波。In one embodiment, the digital processor identifies the pulse wave by identifying real-time pulse characteristics reflected in the digital signal.
数字处理器还可以通过识别数字信号的波动成分和恒定成分得到数字信号反映的实时脉搏特性。The digital processor can also obtain the real-time pulse characteristics reflected by the digital signal by identifying the fluctuation component and the constant component of the digital signal.
在一种实施方式中,统计信息包括脉搏波消停期间的时长,输出模块可以包括显示界面,显示界面用于显示脉搏波消停期间的时长。在另一种实施方式中,统计信息还包括脉搏波消停时间的总占时比,脉搏波消停时间的总占时比为脉搏波消停期间的累积时长与心肺复苏操作时长的比值,显示界面还用于显示所述脉搏波消停时间的总占时比。数字处理器还用于预先设置第一阈值和第二阈值,并在脉搏波消停期间的时长大于第一阈值时,输出报警提示信息;和/或在脉搏波消停时间的总占时比大于所述第二阈值时,输出报警提示信息。In one embodiment, the statistical information includes the duration of the pulse wave stop period, and the output module may include a display interface for displaying the duration of the pulse wave stop period. In another embodiment, the statistical information further includes the total time-consuming ratio of the pulse wave extinction time, and the total time-consuming ratio of the pulse wave extinction time is the ratio of the cumulative duration of the pulse wave extinction period to the cardiopulmonary resuscitation operation duration, and the display interface also It is used to display the total time ratio of the pulse wave extinction time. The digital processor is also used to preset the first threshold and the second threshold, and when the duration of the pulse wave extinction period is greater than the first threshold, output alarm prompt information; and/or when the total time ratio of the pulse wave extinction time is greater than all When the second threshold value is mentioned, the alarm prompt information is output.
以上内容是结合具体的实施方式对本申请所作的进一步详细说明,不能认定本申请的具体实施只局限于这些说明。对于本申请所属技术领域的普通技术人员来说,在不脱离本申请构思的前提下,还可以做出若干简单推演或替换。The above content is a further detailed description of the present application in conjunction with specific embodiments, and it cannot be considered that the specific implementation of the present application is limited to these descriptions. For those of ordinary skill in the technical field to which the present application pertains, some simple deductions or substitutions can also be made without departing from the concept of the present application.
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| US14/497,209 US9949892B2 (en) | 2013-10-11 | 2014-09-25 | Pulse oximetry-based cardio-pulmonary resuscitation (CPR) quality feedback systems and methods |
| EP14186454.6A EP2859913B1 (en) | 2013-10-11 | 2014-09-25 | Pulse oximetry-based Cardio-Pulmonary Resuscitation (CPR) quality feedback systems and methods |
| US15/927,879 US10463566B2 (en) | 2013-10-11 | 2018-03-21 | Pulse oximetry-based cardio-pulmonary resuscitation (CPR) quality feedback systems and methods |
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