CN106031629A - A myopic eye scanning module used for an optical coherence tomography instrument - Google Patents
A myopic eye scanning module used for an optical coherence tomography instrument Download PDFInfo
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- 238000012014 optical coherence tomography Methods 0.000 title claims abstract description 124
- 230000003287 optical effect Effects 0.000 claims abstract description 46
- 210000001525 retina Anatomy 0.000 claims abstract description 41
- 208000001491 myopia Diseases 0.000 claims description 141
- 230000004379 myopia Effects 0.000 claims description 139
- 241000219739 Lens Species 0.000 claims description 92
- 210000000695 crystalline len Anatomy 0.000 claims description 92
- 230000000007 visual effect Effects 0.000 claims description 15
- 230000004323 axial length Effects 0.000 claims description 14
- 230000001143 conditioned effect Effects 0.000 claims description 10
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 238000004026 adhesive bonding Methods 0.000 claims description 4
- 230000001105 regulatory effect Effects 0.000 claims description 4
- 210000001508 eye Anatomy 0.000 abstract description 71
- 238000003384 imaging method Methods 0.000 abstract description 12
- 230000036040 emmetropia Effects 0.000 abstract description 6
- 210000001747 pupil Anatomy 0.000 description 12
- 230000006870 function Effects 0.000 description 10
- 239000013307 optical fiber Substances 0.000 description 9
- 208000014733 refractive error Diseases 0.000 description 9
- 238000010586 diagram Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 230000004329 axial myopia Effects 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000012545 processing Methods 0.000 description 4
- 210000005252 bulbus oculi Anatomy 0.000 description 3
- 238000012937 correction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
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- 238000003759 clinical diagnosis Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
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- 230000008844 regulatory mechanism Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000009738 saturating Methods 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000010408 sweeping Methods 0.000 description 2
- 238000003325 tomography Methods 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 208000029091 Refraction disease Diseases 0.000 description 1
- 230000004430 ametropia Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 239000000571 coke Substances 0.000 description 1
- 230000004340 degenerative myopia Effects 0.000 description 1
- 208000001309 degenerative myopia Diseases 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 210000004220 fundus oculi Anatomy 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
- A61B3/1225—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/02055—Reduction or prevention of errors; Testing; Calibration
- G01B9/02062—Active error reduction, i.e. varying with time
- G01B9/02063—Active error reduction, i.e. varying with time by particular alignment of focus position, e.g. dynamic focussing in optical coherence tomography
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/0209—Low-coherence interferometers
- G01B9/02091—Tomographic interferometers, e.g. based on optical coherence
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Abstract
An optical coherence tomography instrument comprises an optical coherence tomography module used for retina scanning for emmetropia eyes and a myopic eye scanning module which can be attached to the outside of the optical coherence tomography module to realize switching of a scanning function for emmetropia eyes and a scanning function for myopic eyes with elongating ocular axes of the optical coherence tomography instrument. The myopic eye scanning module has a negative focal power, so that scanning light beams from the optical coherence tomography instrument are diffused before entering myopic eyes with elongating ocular axes and further the focusing angle of scanning light beams focused on retinas of the myopic eyes with elongating ocular axes is increased and the maximum optical path difference spanned by imaging areas of the retinas is reduced. Thus, error-free mirror image scanning images with stronger scanning signals and higher signal-to-noise ratios can be obtained.
Description
Technical field
The present invention relates to optical medical field, particularly to a kind of optics with myopia scan module
Coherence tomograph (OCT System, Optical Coherence Tomography System).
Background technology
Optical coherence tomography is a kind of interferometric method, for obtaining the scattering of scanned sample
Characteristic.OCT can be divided into Time Domain Optical coherence tomograph (TD-OCT)
With domain optical coherence tomoscanner (FD-OCT) two kinds.With Time Domain Optical coherence tomography
Technology is compared, and domain optical coherence layer scanning technology has the most excellent in terms of speed and signal to noise ratio
Gesture.The spectral information of domain optical coherence tomoscan differentiates generally to be accomplished by: in spectrum
In the case of domain optical coherence tomoscan (SD-OCT), it is possible to use the spectrometer in feeler arm
Carry out light splitting；In the case of frequency sweep (length scanning) optical coherence tomography (SS-OCT),
Spectral information can be obtained by the frequency converting LASER Light Source rapidly.
Fig. 1 shows the FD-OCT system for collecting 3D rendering data of prior art.
FD-OCT system includes that light source 101, traditional light source include but not limited to have temporal coherent length
Shorter wideband light source or scanning lasing light emitter.From light source 101 light generally by optical fiber 105 guide with
Illuminating sample 110, typical sample is the tissue at the rear portion of human eye.Light is generally by means of scanning device 107
Scan between optical fiber and sample, so that light beam (dotted line 108) scanned region or volume
It is imaged.Being collected from the light of sample scattering, typical case is collected into and the light illuminating sample for guiding
The identical optical fiber 105 of optical fiber in.The reference light obtained from identical light source 101 is in independent path
Upper transmission, in this case, including optical fiber 103 and retroeflector 104.People in the art
Member is it is conceivable that conduct reference path can also be utilized.The sample light collected is generally at fiber coupler
Be combined with reference light in 102, thus in detector 120, form the interference of light.From detector output
Data are transmitted to processor 130.Result can store within a processor or be illustrated in display
On device 140.Process and storage function can realize inside OCT, or also
Can manage unit in the outside to realize, the data being collected can be transferred to this external processing unit.
This external processing unit can be specifically designed to data and process, or can also carry out other be not limited to light
Learn the common task of coherence tomography function.
The reference arm of sample and interferometer can form bulk-optics, optical fibers or bulk-optic
Hybrid system, and can have different structures, such as Michelson, Mach-Zehnder or
Person's design based on shared path well known by persons skilled in the art.Light beam used herein is to be understood that
Light path for any careful guiding.In time domain system, reference arm need to have adjustable light delay from
And produce interference.The detection system of balance generally can be used in TD-OCT system and SS-OCT system
In, and spectrometer is generally used for the detection port of SD-OCT system.Invention described herein is permissible
For any kind of OCT system.OCT system generally can encapsulate in the housing, and it has bag
Include multiple patient's setting element of lower jaw frame and the headstock.
In prior art, OCT has been used for sweeping the retina of patient
Retouch, thus carry out assisted medical diagnosis.Fig. 2 shows in prior art for the retina to patient
The one of the optical coherence tomography module of the OCT being scanned is embodied as
Mode, the optical coherence tomography module shown in Fig. 2 includes optical fiber 1, collimating mirror 2, dispersion compensation
Post 3, X/Y scanning element 4, retina scanning lens 5, eyeglass 6 and be positioned at retina and sweep
Retouch the optical mirror for light path folding between lens 5 and eyeglass 6, thus collimation is provided
Incident scanning optical bundle is to schematic eyes 8.
The light source of OCT can be the shorter broadband light source of coherence length or
Frequency scanning laser.The light that these light sources send is swept via the optical coherence tomography that leads into of optical fiber 1
Retouch system.Optical fiber 1 it is collected into again, the sample light being collected and ginseng from the light of sample reflection/scattering
Examining light and form the interference of light in intervention module in (not shown), optical interference signals (is not shown by detector
Go out) receive.It is transferred to processor (not shown) from the data of detector output.Result can
Within a processor or show over the display with storage.Process and storage function can be at optical coherence
Tomoscanner is internal to be realized, or can also manage unit realization in the outside, and the data being collected can
To be transferred to this external processing unit.This external processing unit can be specifically designed to data and process, or
Person can also carry out other the common task being not limited to optical coherence tomography function.
At a certain distance from OCT can be placed in before eyes 8, optical coherence breaks
(emergent pupil, exit pupil, namely from OCT for the emergent pupil of layer scanner
The pivotal point of single scanning light beam) be in the position of the pupil of eyes.As in figure 2 it is shown, from light
The single scanning light beam learning coherence tomograph all can focus to the retina of eyes 8, single scanning
Light beam focusing angle is α1, corresponding numerical aperture N.A.=n_eyeball (refractive index of eyeball) *
sin(α1), this numerical aperture N.A. determines the intensity (signal to noise ratio) of obtained scanning signal.Right
For an emmetropic eye (emmetropic eye), along with the scanning of light beam, a lot of are not
(this patent on the amphiblestroid diverse location of eyes 8 is focused on the single scanning light beam of incident angle
" scanning light beam " mentioned by refers to single scanning light beam or by multiple such single scanning light beam structures
The set become), the chief ray of these single scanning light beams forms a visual field (angle) on the retina
β (FOV, i.e. scanning angle β), covers the retinal area of certain angle in a lateral direction, by
This maximum optical path difference (Maximum crossed over by amphiblestroid imaging region in the degree of depth formed
OPD, i.e. Maximum Optical Path Difference) H1。
Myopia is a kind of common ametropia phenomenon, in OCT clinical diagnosis
In often can run into myopia.Further, existing research display pathological myopia can increase some eye
The probability of end disease, these fundus oculi diseases can be by OCT auxiliary diagnosis, thus
Too increase myopia in clinical diagnosis and need to use the probability of OCT.
(a) and (b) in Fig. 3 is shown respectively and utilizes existing OCT to sweep
Retouch emmetropic eye and bathomorphic single order optical schematic diagram.Compared with the situation of scanning emmetropic eye
Relatively, in the prior art, when scanning myopia, its compensation principle is according to checked eyes
Refractive error size, makes the outgoing scanning light beam of coherence tomograph become corresponding divergent beams,
So that scanning light beam focuses on myopia retina again.Can be such as by changing retina scanning
The distance between distance or change light source and collimating mirror between lens 5 and eyeglass 6 is come tested
The refractive error of the eyes looked into compensates, the OCT system released in 2007 such as Zeiss company.
Such as, as shown in (b) in Fig. 3, the distance between retina scanning lens and eyeglass is permissible
Being shortened, the scanning light beam of outgoing becomes divergent beams, and the pupil of checked eyes is positioned at eyeglass
Focus so that the pupil of eyes is positioned at the multi beam scanning light beam from OCT
Pivotal point.Under this regulatory mechanism, according to first-order theory character, provable incidence is emmetropia
The single scanning light beam diameter of section (H_eye) of eye is equal to adjusting retina scanning lens and eyeglass
Between distance after the bathomorphic single scanning light beam diameter of section of incidence (H ' _ eye), i.e.Wherein, Δ is between retina scanning lens and eyeglass
The distance being conditioned, f2Being the focal length of eyeglass, d is the distance between eyeglass and the pupil of eyes
And equal to f2.And as shown in Figure 3, the space between retina scanning lens and eyeglass is
The parallel space of each scanning light beam chief ray, the distance change between retina scanning lens and eyeglass
Do not interfere with the visual field β of each scanning light beam chief ray after eyeglass.
Myopia specifically includes two types, and the myopia of one of which type is axial myopia eye, axle
Property myopia is relevant with axiallength elongation.The axial myopia eye of axiallength elongation causes corneal curvature
Increase.Another type of myopia is retractive myopia eye, retractive myopia eye and inside ofeye
The refractive status of tissue is relevant.
(a) and (b) in Fig. 4 is shown respectively retractive myopia eye and the tool with normal axis oculi
There is the axial myopia eye of the axis oculi of elongation.Axiallength is still kept to normal retractive myopia eye,
Distance L between retina and the pupil of eyes ' eye is substantially equal to retina and the pupil of emmetropic eye
Distance Leye between hole, this distance about 20mm.Under existing regulatory mechanism effect, this
Time OCT numerical aperture N.A. in the case of emmetropic eye equal to OCT at retractive myopia eye
In the case of numerical aperture N.A. ', that is:
N.A. '=n_eyeball*sin (α1)≈n_eyeball*tg(α1)=n_eyeball* (H ' _ eye/L ' eye)=n
_ eyeball* (H_eye/Leye)=N.A. (H ' _ eye and H_eye demonstrate,proved identical, and it is respectively incidence and bends
Light normal eyes and compensate the diameter of section of incident bathomorphic single scanning light beam after adjustment).And
And, owing to visual field and the axiallength of scanning light beam chief ray all do not change, axiallength is normal
The maximum optical path difference crossed over by amphiblestroid imaging region in the degree of depth of retractive myopia eye also keep
Identical with normal eyes.
But, according to medical research, most of high myopic eyes are generally by the axial length elongation of axis oculi
Caused, i.e. be there is axial myopia.For axial myopia eye, existing refraction compensation mechanism then can be produced
More raw problems.
Fig. 5 illustrates based on the principle same with Fig. 3 and utilizes existing OCT to sweep
The bathomorphic schematic diagram of the axis oculi retouching emmetropic eye and there is elongation.As it is shown in figure 5, for tool
There is the myopia of the axis oculi of elongation.Distance between retina scanning lens 5 and eyeglass 6 is shortened
So that scanning light beam focuses to retina again to compensate scanned bathomorphic refractive error.
Single scanning light beam focusing angle α after compensation2Scanning light beam focusing angle α less than normal eyes1.Institute
With, although scanning light beam diameter of section H_eye keeps constant as previously analyzed, but with emmetropia
The situation of eye is compared, and owing to axis oculi extends with coefficient (L_eye+ δ L)/L_eye, wherein L_eye is mark
The axis oculi of quasi-normal eyes is long, sin (α2) and tg (α2) compare sin (α1) and tg (α1) reduce.Therefore, at tool
Have elongation axis oculi bathomorphic in the case of, numerical aperture N.A.=n_eyeball* of OCT
sin(α2)≈n_eyeball*tg(α2) can diminish.Owing to OCT is at the numerical aperture reduced
In the case of footpath from retina collect signal, so, it is thus achieved that scanning signal intensity relative to not having
The situation of axis oculi elongation reduces, and this causes the signal to noise ratio scanning signal less than the situation not having axis oculi to extend.
Further, since in compensation process the visual field β of scanning light beam chief ray1Do not change, institute
The maximum optical path difference H that the myopia retina extended by axis oculi with scanning light beam chief ray is formed2It is more than
The maximum optical path difference H formed on the retina of emmetropic eye1.Due to current domain optical coherence
Tomoscanner only supports limited scan depths scope, amphiblestroid the imaging region maximum crossed over
Optical path difference exceedes the maximum scan degree of depth of OCT can cause optical coherence tomography
Instrument produces " mirror image " scanogram of mistake.Such as, Fig. 6 shows " mirror image " of this mistake
Scanogram.In frequency domain OCT, the energy spectral density signal that spectroscope obtains, become through Fourier
Sample depth direction signal is obtained after changing.For any real number signal a (ν),
If FT [c (v)]=C (t), thenThis signal symmetrically divides about zero-bit
Cloth.Owing to the spectrum density of energy is real number signal, from fourier transform property, it is possible to obtain two
The individual depth direction signal about depth zero positional symmetry, therefore, when object is spanned depth zero position
During measurement, owing to depth difference is more than the scan depths of OCT, thus create zero
Before depth location (on) the mirror image of a part of object and be folded into horizontal stroke as shown in Figure 6
To scanogram.
In sum, in prior art, utilizing OCT, myopia is swept
Retouch and there is certain defect.Adjust if, with the distance between retina scanning lens and eyeglass,
Refractive error correction can be carried out, but, for the myopia of axis oculi elongation, single scanning light beam
Focusing angle is less than the focusing angle of the scanning light beam of emmetropic eye, so that the numerical value of whole system
Aperture diminishes, and causes the intensity of the scanning signal obtained to reduce relative to the situation of emmetropic eye, sweeps
The signal to noise ratio retouching signal is less compared with the situation of emmetropic eyes.Further, since axis oculi elongation
With the increase of retina curvature, the maximum optical path difference meeting crossed over by amphiblestroid imaging region in the degree of depth
Increase.Owing to current domain optical coherence tomoscanner only supports limited scan depths scope, depending on
The increase of the maximum optical path difference of the imaging region of nethike embrane can cause OCT to produce mistake
" mirror image " scanogram.
Summary of the invention
In order to solve the problems referred to above, the OCT that the present invention provides includes: for right
Emmetropic eye carries out the optical coherence tomography module of retina scanning, described optical coherence tomography
Scanner also includes that myopia scan module, described myopia scan module can be attached to described optics
The outside of coherence tomography module, in order to realize described OCT to emmetropia
The scan function of eye and the conversion of the bathomorphic scan function to axis oculi elongation；Described myopia scans
Module has negative power.
In one preferred embodiment, myopia scan module can make from optical coherence tomography
The scanning light beam of scanner produced before entering the myopia of axis oculi elongation and dissipates, thus increased focusing
The focusing angle of the scanning light beam on the bathomorphic retina of axis oculi elongation.This has negative light simultaneously
The external myopia scan module of focal power makes the key light of the scanning light beam from OCT
The visual field of line reduces, thus reduces the maximum optical path difference crossed over by amphiblestroid imaging region.
In one preferred embodiment, described myopia scan module is independent detachable module,
And the outside of described optical coherence tomography module can be attached to.
In one preferred embodiment, described myopia scan module includes that one or more list is saturating
Mirror, cemented doublet, many balsaming lenss, reflection border or the simple lens of variable optical strength.
In one preferred embodiment, described myopia scan module can be a series, series
Include multiple module with different fixing focal power.Preferably, there is the mould of bigger negative power
Block extends longer myopia for axiallength, and the module with less negative power is long for axis oculi
The myopia that degree elongation is shorter.
In one preferred embodiment, described myopia scan module include having such as simple lens,
Signal-lens multiple lens of cemented doublet, many balsaming lenss, reflection border or variable optical strength
Variable focus lens package, the focal power of described variable focus lens package can be conditioned.Preferably, by regulation institute
State the distance between multiple lens of variable focus lens package or by regulating the signal-lens of variable optical strength
Focal power regulates the focal power of described variable focus lens package.Preferably, described variable focus lens package is multiple
Distance between lens can be conditioned by electric or hand mode.
In one preferred embodiment, the retina scanning of described optical coherence tomography module
Distance scalable between lens and eyeglass.
In one preferred embodiment, the light source of described optical coherence tomography module and collimation
Distance scalable between mirror.
Present invention also offers the myopia scan module for OCT, described light
Learn coherence tomograph and include the optical coherence tomography module for carrying out retina scanning, its
In, described myopia scan module can be attached to the outside of described optical coherence tomography module,
To realize described OCT to the scan function of emmetropic eye with to axis oculi elongation
The conversion of bathomorphic scan function；Described myopia scan module has negative power.
In one preferred embodiment, myopia scan module can make from optical coherence tomography
The scanning light beam of scanner produced before entering the myopia of axis oculi elongation and dissipates, thus increased focusing
The focusing angle of the scanning light beam on the bathomorphic retina of axis oculi elongation, and reduce from light
Learn the visual field of the chief ray of the scanning light beam of coherence tomograph.
In one preferred embodiment, described myopia scan module is independent detachable module,
And the outside of described optical coherence tomography module can be attached to.
In one preferred embodiment, described myopia scan module includes that one or more is single
Lens, cemented doublet, many balsaming lenss, reflection border or the simple lens of variable optical strength.
In one preferred embodiment, described myopia scan module can be a series of modules,
In series, each module has different focal power.
In one preferred embodiment, have the myopia scan module of bigger negative power for
The myopia that axiallength elongation is longer, has the myopia scan module of less negative power for eye
The myopia that shaft length elongation is shorter.
In one preferred embodiment, described myopia scan module include having such as simple lens,
Signal-lens multiple lens of cemented doublet, many balsaming lenss, reflection border or variable optical strength
Variable focus lens package, the focal power of described variable focus lens package can be conditioned.Preferably, by regulation institute
State the distance between multiple lens of variable focus lens package or by regulating the signal-lens of variable optical strength
Focal power regulates the focal power of described variable focus lens package.Preferably, described variable focus lens package is multiple
Distance between lens can be conditioned by electric or hand mode.
Compared with prior art, the OCT of the present invention at least has the advantage that
Owing to the myopia scan module in the OCT of the present invention has negative power, make
Must produce before entering the myopia of axis oculi elongation from the scanning light beam of OCT
Dissipate, and the visual field of the chief ray of scanning light beam reduces, thus increase the myopia focusing on axis oculi elongation
The focusing angle and reducing of the scanning light beam on the retina of eye is crossed over by amphiblestroid imaging region
Maximum optical path difference, to obtain stronger scanning signal (bigger signal to noise ratio) and to avoid " the mirror of mistake
Picture " scanogram.
Accompanying drawing explanation
Fig. 1 shows the schematic diagram of OCT of the prior art；
Fig. 2 shows another schematic diagram of OCT of the prior art；
Fig. 3 shows and utilizes existing OCT to scan emmetropic eye and myopia
The schematic diagram of eye；
Fig. 4 shows the bathomorphic schematic diagram of the axis oculi having normal axis oculi and have elongation；
Fig. 5 shows that another utilizes existing OCT to scan emmetropic eye
Bathomorphic schematic diagram with the axis oculi with elongation；
Fig. 6 shows axis oculi near utilizing the scanning of existing OCT to have elongation
" mirror image " scanogram obtained depending on eye；
Fig. 7 shows the optical coherence tomography with additional myopia scan module of the present invention
The schematic diagram of instrument；
Fig. 8 shows the optical coherence tomography with additional myopia scan module of the present invention
One detailed description of the invention of instrument；
Fig. 9 shows the optical coherence tomography with additional myopia scan module of the present invention
The another embodiment of instrument.
Detailed description of the invention
OCT according to an embodiment of the invention is described with reference to the accompanying drawings.Under
In the description in face, elaborate that many details are to make person of ordinary skill in the field more comprehensively
The present invention is understood on ground.But, for the technical staff in art it is evident that the present invention
Realization can not have some in these details.However, it should be understood that the present invention is also
It is not limited to introduced specific embodiment.On the contrary, it may be considered that any by following feature and key element
Combination implements the present invention, regardless of whether whether they relate to different embodiments.Therefore, side below
Face, feature, embodiment and advantage be used for illustrative purposes only and be not construed as claim key element or
Limit, unless the most clearly proposed.
Fig. 7 shows the optical coherence tomography with additional myopia scan module of the present invention
Instrument, in the OCT shown in Fig. 7, except for the view to emmetropic eye
Outside the conventional optics of the OCT that film is scanned, also include adding is near
Depending on eye scan module, the myopia scan module 7 with negative power is attached to existing optics phase
The outside of the mechanical interface of dry tomoscanner, in order to dioptric just realizing OCT
The scan function of normal eye and the conversion of the bathomorphic scan function to axis oculi elongation.Additional myopia
Scan module 7 is placed in the outside of eyeglass 6, and myopia scan module 7 has negative power, from
The each of eyeglass 6 opening OCT restraints single scanning light beam by additional myopia
Can become more to dissipate, so that scanning light beam is at the pupil position of eyes after eye scan module 7
Beam cross section diameter increase.Owing to scanning light beam increases at the beam cross section diameter of pupil position, from
And increase the focusing angle of the scanning light beam on the bathomorphic retina focusing on axis oculi elongation.Meanwhile,
The chief ray of scanning light beam via have negative power additional myopia scan module 7 after visual field become
It is little, so that the maximum optical path difference crossed over by amphiblestroid imaging region reduces.As it is shown in fig. 7,
Owing to being attached the myopia scan module 7 with negative power, add scanning light beam focusing angle
And decrease the maximum optical path difference crossed over by amphiblestroid imaging region, i.e. due to scanning light beam
Dissipate, there is the scanning light beam focusing angle α of additional myopia scan module3More than the most additional myopia
The scanning light beam focusing angle α of eye scan module2.According to numerical aperture formula N.A.=n_eyeball
(refractive index of eyeball) * sin (α 3), is attached the myopia scan module 7 with negative power
Numerical aperture N.A. of OCT increases accordingly, it might even be possible to increase to ratio the most attached
When adding myopia scan module, numerical aperture N.A. of scanning emmetropic eye also wants big.It addition, respectively sweep
Retouching beam primary light line under the effect of near-sighted scan module 7 with negative power, its visual field can reduce,
The visual field β 3 of the scanning light beam chief ray i.e. with additional myopia scan module is near less than the most additional
Depending on the visual field β 2 (β 1 equal in background technology) of the scanning light beam chief ray of eye scan module, from
And maximum optical path difference H when making to have additional myopia scan module3Sweep less than the most additional myopia
Retouch maximum optical path difference H during module2.Therefore, it is being attached the near-sighted scan module with negative power
After 7, focus on the focusing angle of scanning light beam on the bathomorphic retina of the axis oculi with elongation
Degree is replied and keeps and scan emmetropia at the moment approximately equal, thus scans with the most additional myopia
Module and using compensates the myopia that the method scanning of refractive error has the axis oculi of elongation in prior art
Situation compare and obtain stronger scanning signal (signal to noise ratio), and, additional owing to make use of
Myopia scan module, the visual field of scanning light beam reduces, amphiblestroid imaging region the maximum crossed over
Optical path difference reduces the most accordingly, avoids " mirror image " scanogram of mistake the most in most cases.
In the present invention, it is not necessary to the refractive error correction mechanism of existing OCT, i.e.
Without the distance between retina scanning lens and the eyeglass in OCT is carried out
Regulation, by means of the additional myopia scan module with negative power, can be to having elongation
The high myopic eye of axis oculi is scanned, it is thus achieved that stronger scanning signal (signal to noise ratio) and can avoid mistake
" mirror image " scanogram by mistake.If technical scheme is swept with existing optical coherence tomography
The refractive error correction mechanism retouching instrument combines, then can further expand refractive error correcting range.
In the present invention, additional lens numbers, type and focal length in myopia scan module are variable
's.Such as, additional myopia scan module can include one or more simple lens, double gluing
Lens, many balsaming lenss or the battery of lens being made up of several lens, if simple lens, double gluing
The equivalent negative focal power of the myopia scan module that lens, many balsaming lenss or battery of lens are constituted is permissible
Meet the bathomorphic scanning demand for certain dioptric scope.Preferably, described myopia is swept
Retouching module can use multiple lens with different fixing focal power or zoom system, pancreatic system to cover bigger
Myopia power range, the focal power of described zoom-lens system can be conditioned.Zoom lens system
System can include simple lens, cemented doublet, many balsaming lenss, reflection border, the list of variable optical strength
Lens (i.e. liquid lens).In actual product, described myopia scan module can be a mould
Block series, in series, each module has different negative power.
Fig. 8 illustrates the OCT with additional myopia scan module of the present invention
A detailed description of the invention, which comprises two cemented doublets with fixing focal power
Myopia scan module.In Fig. 8 (a), for the myopia that axiallength elongation is bigger, can make
Myopia scan module with the cemented doublet with stronger negative power.And in Fig. 8 (b),
For the myopia that axiallength elongation is less, it is possible to use have the double glued of more weak negative power
The myopia scan module of lens.
Fig. 9 illustrates the OCT with additional myopia scan module of the present invention
Another embodiment.As it is shown in figure 9, myopia scan module 7 is to include two lens
The zoom system, pancreatic system of 7-1,7-2, one of them lens 7-1 can have negative power, and another is saturating
Mirror 7-2 then has positive light coke, and the zoom system, pancreatic system that they are formed has negative power.Fig. 9 (a)
To 9 (c) show the spacing of two lens 7-1,7-2 from little to big different conditions, by regulation
Distance between two lens 7-1,7-2 of zoom system, pancreatic system, myopia scan module 7 can cover one
Determine the myopia diopter (corresponding to having the myopia of different axis oculi elongation) of scope.Specifically,
When the myopia bigger for axis oculi elongation, can be by the two of zoom system, pancreatic system lens 7-1,7-2
It is adjusted to that there is less spacing, when the myopia less for axis oculi elongation, can be by zoom
Two lens 7-1,7-2 of system are adjusted to have bigger spacing.Specifically, can be by electronic
Or manual mode regulates the distance between the lens in zoom system, pancreatic system, this zoom system, pancreatic system may also comprise
Plural lens or battery of lens.
The OCT with myopia scan module in the present invention can not change
Existing OCT internal structure, do not increase the one-tenth of OCT itself
Defect of the prior art is overcome on the basis of Ben.Owing to myopia scan module has negative power,
The scanning light beam from OCT is made to enter the bathomorphic pupil that axis oculi extends
Produce before and dissipate, thus increase the scanning light beam on the bathomorphic retina focusing on axis oculi elongation
Focusing angle.And make the visual field of the scanning light beam chief ray from OCT
Diminish the maximum optical path difference crossed over by amphiblestroid imaging region with minimizing.Thus obtain stronger sweeping
Retouch signal (signal to noise ratio), and avoid " mirror image " scanogram of mistake.
It addition, by the present invention describe myopia scan module be used for normal eye scan time, owing to regarding
Field diminishes, and actual sweep limits on normal retina diminishes the most accordingly.Now OCT instrument will
Less sweep limits still shows in identical viewing area, serves one and scans normal eye
Carry out the effect of partial enlargement.
Although the present invention discloses as above with preferred embodiment, but the present invention is not limited to this.Any
Those skilled in the art, the various changes made without departing from the spirit and scope of the present invention and amendment,
All should include in protection scope of the present invention, therefore protection scope of the present invention should be with claim institute
Limit in the range of standard.
Claims (20)
1. having an OCT for myopia scan module, described optical coherence breaks
Layer scanner includes the optical coherence tomography module for carrying out retina scanning,
It is characterized in that, described OCT also includes myopia scan module, described
Myopia scan module can be attached to the outside of described optical coherence tomography module, in order to realizes
Described OCT is to the scan function of emmetropic eye and the myopia to axis oculi elongation
The conversion of scan function；
Described myopia scan module has negative power.
The optical coherence tomography with myopia scan module the most according to claim 1
Instrument, it is characterised in that myopia scan module can make the scanning from OCT
Light beam produced before entering the myopia of axis oculi elongation and dissipates, thus increased and focus on axis oculi elongation
The focusing angle of the scanning light beam on bathomorphic retina, and reduce and sweep from optical coherence tomography
Retouch the visual field of the chief ray of the scanning light beam of instrument.
The optical coherence tomography with myopia scan module the most according to claim 1
Instrument, it is characterised in that described myopia scan module is independent detachable module, and can be attached
It is connected to the outside of described optical coherence tomography module.
The optical coherence tomography with myopia scan module the most according to claim 1
Instrument, it is characterised in that described myopia scan module includes one or more simple lens, double gluing
Lens, many balsaming lenss, reflection border or the simple lens of variable optical strength.
The optical coherence tomography with myopia scan module the most according to claim 1
Instrument, it is characterised in that described myopia scan module can be a series of modules, each in series
Module has different focal power.
The optical coherence tomography with myopia scan module the most according to claim 5
Instrument, it is characterised in that the myopia scan module with bigger negative power extends for axiallength
Longer myopia, the myopia scan module with less negative power extends relatively for axiallength
Short myopia.
The optical coherence tomography with myopia scan module the most according to claim 1
Instrument, it is characterised in that described myopia scan module include having such as simple lens, cemented doublet,
The variable focus lens package of signal-lens multiple lens of many balsaming lenss, reflection border or variable optical strength,
The focal power of described variable focus lens package can be conditioned.
The optical coherence tomography with myopia scan module the most according to claim 7
Instrument, it is characterised in that by regulating the distance between multiple lens of described variable focus lens package or logical
Overregulate the signal-lens focal power of variable optical strength to regulate the focal power of described variable focus lens package.
The optical coherence tomography with myopia scan module the most according to claim 8
Instrument, it is characterised in that the distance between multiple lens of described variable focus lens package can by electronic or
Manual mode is conditioned.
The optical coherence tomography with myopia scan module the most according to claim 1
Instrument, it is characterised in that the retina scanning lens of described optical coherence tomography module and eyeglass
Between distance scalable.
11. optical coherence tomographies with myopia scan module according to claim 1
Instrument, it is characterised in that the distance between light source and the collimating mirror of described optical coherence tomography module
Scalable.
12. 1 kinds of myopia scan modules for OCT, described optical coherence
Tomoscanner includes the optical coherence tomography module for carrying out retina scanning,
It is characterized in that, described myopia scan module can be attached to described optical coherence tomography
The outside of module, in order to realize the described OCT scan function to emmetropic eye
Conversion with the bathomorphic scan function that axis oculi is extended；
Described myopia scan module has negative power.
13. myopia for OCT according to claim 12 scan mould
Block, it is characterised in that myopia scan module can make the scanning from OCT
Light beam produced before entering the myopia of axis oculi elongation and dissipates, thus increased and focus on axis oculi elongation
The focusing angle of the scanning light beam on bathomorphic retina, and reduce and sweep from optical coherence tomography
Retouch the visual field of the chief ray of the scanning light beam of instrument.
14. myopia for OCT according to claim 12 scan mould
Block, it is characterised in that described myopia scan module is independent detachable module, and can be attached
It is connected to the outside of described optical coherence tomography module.
15. myopia for OCT according to claim 12 scan mould
Block, it is characterised in that described myopia scan module includes one or more simple lens, double gluing
Lens, many balsaming lenss, reflection border or the simple lens of variable optical strength.
16. myopia for OCT according to claim 12 scan mould
Block, it is characterised in that described myopia scan module can be a series of modules, each in series
Module has different focal power.
17. myopia for OCT according to claim 16 scan mould
Block, it is characterised in that the myopia scan module with bigger negative power extends for axiallength
Longer myopia, the myopia scan module with less negative power extends relatively for axiallength
Short myopia.
18. myopia for OCT according to claim 12 scan mould
Block, it is characterised in that described myopia scan module include having such as simple lens, cemented doublet,
The variable focus lens package of signal-lens multiple lens of many balsaming lenss, reflection border or variable optical strength,
The focal power of described variable focus lens package can be conditioned.
19. myopia for OCT according to claim 18 scan mould
Block, it is characterised in that by regulating the distance between multiple lens of described variable focus lens package or logical
Overregulate the signal-lens focal power of variable optical strength to regulate the focal power of described variable focus lens package.
20. myopia for OCT according to claim 19 scan mould
Block, it is characterised in that the distance between multiple lens of described variable focus lens package can by electronic or
Manual mode is conditioned.
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| CN201510104688.2A CN106031629A (en) | 2015-03-10 | 2015-03-10 | A myopic eye scanning module used for an optical coherence tomography instrument |
| PCT/EP2016/055055 WO2016142435A1 (en) | 2015-03-10 | 2016-03-09 | Myopia scan module for optical coherence tomography system |
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| CN113939220A (en) * | 2019-05-31 | 2022-01-14 | 株式会社尼康 | Ophthalmology device and tomographic image generation device |
| CN114271782A (en) * | 2021-11-30 | 2022-04-05 | 视微影像(河南)科技有限公司 | Eye fundus imaging eyepiece capable of being switched to wide angle/ultra-wide angle |
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