CN106620018A - Health-care product with anti-radiation effect and preparation method thereof - Google Patents

Abstract

The invention discloses a health care product with anti-radiation effect and a preparation method thereof, wherein the health care product is prepared from the following ingredients by weight: 20-30 parts of red raspberry, 15-25 parts of blackberry, and 10 parts of mulberry ～20 parts, 12～15 parts of medlar, 8～12 parts of black currant, 7～15 parts of Houttuynia cordata, 5～10 parts of Rhodiola rosea, 3～8 parts of poria cocos, 5～10 parts of tangerine peel, 6～10 parts of hawthorn 3-6 parts of Radix Astragali, 5-10 parts of Rhizoma Chuanxiong, and 3-8 parts of Atractylodes Rhizoma. The preparation method of the health care product is carried out according to the following steps: Weigh the raw materials, soak them in water, and decoct 3 times to separate the medicinal liquid; coarsely filter the medicinal liquid, mix them, cool and stand still, and take the supernatant; add 5g of Add methylparaben powder according to the ratio of methylparaben, stir while adding, mix well, after standing still, filter with filter cloth; sterilize, disinfect and package the obtained filtrate to make oral liquid preparation .

Description

A health care product with anti-radiation effect and preparation method thereof

technical field

The invention belongs to the technical field of food, medicine and health products, and relates to a health product with anti-radiation effect and a preparation method thereof.

Background technique

Radioactive substances are widely used in science and technology, production and daily life, which will inevitably cause radioactive pollution and radiation hazards to people's living environment and human body, and the seriousness of the harm to human body has also attracted increasing attention. So far, in the clinical treatment of malignant tumor patients, more than 70% of cancer patients cannot do without radiotherapy. After radiotherapy, a large amount of active oxygen is produced in the patient's body, and lipid peroxidation caused by excessive active oxygen destroys the structure of the membrane and damages Proteins and nucleic acids have a serious impact on human health. Now that people cannot avoid radiation, how to prevent problems before they happen and how to reduce the damage caused by radiation to human beings has attracted widespread attention.

In addition to physical measures, the current protection against radiation damage mainly focuses on drug protection. Due to the adverse reactions of drugs more or less, coupled with cost factors, it is difficult for drugs to be used as conventional preparations in radiation protection. Since ancient times, Eastern Asian countries have had a tradition of homology of medicine and food, and they have paid great attention to the development of health food and functional food. Functional food additives, especially the obvious efficacy of some natural extracts, have long been recognized internationally.

Contents of the invention

In order to achieve the above purpose, the present invention provides a health care product with anti-radiation effect and its preparation method, which solves the problem in the prior art that the radiation of radiotherapy causes damage to the human body.

The technical solution adopted in the present invention is, a health care product with anti-radiation effect, which is formed by the following raw materials in parts by weight: 20-30 parts of red raspberry, 15-25 parts of blackberry, and 10-20 parts of mulberry , 12-15 parts of medlar, 8-12 parts of black currant, 7-15 parts of Houttuynia cordata, 5-10 parts of rhodiola rosea, 3-8 parts of Poria cocos, 5-10 parts of tangerine peel, 6-10 parts of hawthorn, 6-10 parts of astragalus 3-6 parts, Chuanxiong 5-10 parts, Atractylodes macrocephala 3-8 parts.

Another technical solution adopted by the present invention is that the preparation method of the health product with anti-radiation effect is specifically carried out according to the following steps:

Step 1, weigh 20-30 parts of red raspberry, 15-25 parts of blackberry, 10-20 parts of mulberry, 12-15 parts of medlar, 8-12 parts of black currant, 7-15 parts of Houttuynia cordata, Rhodiola rosea 5-10 parts, 3-8 parts of Poria cocos, 5-10 parts of tangerine peel, 6-10 parts of hawthorn, 3-6 parts of astragalus, 5-10 parts of Chuanxiong, 3-8 parts of Atractylodes macrocephala, add 8-15 times of water to soak Decoct 3 times, separate the liquid medicine;

Step 2, coarsely filter the medicinal liquid decocted for 3 times in step 1, mix the filtrate, cool and stand for 2 to 4 hours, and take the supernatant;

Step 3, take the supernatant obtained in step 2, add methylparaben powder according to the ratio of 5g methylparaben per 1kg solution, stir while adding, mix well, and let it stand for 3 to 6 hours , filter with filter cloth;

Step 4, sterilizing, disinfecting and packaging the filtrate obtained in step 3 to make an oral liquid preparation.

In the above step 1, soak in water for 3 to 6 hours; decoct for 1.5 to 2.5 hours each time.

In the above step 2, the filtrate is cooled to 15°C to 25°C.

The beneficial effect of the invention is that the medicine of the invention can improve the immune function of the body, can remove free radicals in the body, protect the hematopoietic function, and is suitable for preventing and treating body damage caused by radiation.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. Those skilled in the art can also obtain other drawings based on these drawings without creative work.

Fig. 1 is a kind of health product with anti-radiation effect of the present invention and preparation method drug effect test in each group's lymphocyte DNA damage situation figure of rat;

Fig. 2 is a diagram of the influence of compound raspberry seed powder on rat lymphocyte DNA in a health product with anti-radiation effect and its preparation method in the efficacy test of the present invention.

Among them, Fig. 2A. Blank control group, Fig. 2B. Simple radiation group, Fig. 2C. Vitamin combined application group, Fig. 2D. Compound raspberry seed powder group.

detailed description

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

The health care product with anti-radiation effect of the present invention is prepared from the following raw materials by weight: 20-30 parts of red raspberry, 15-25 parts of blackberry, 10-20 parts of mulberry, and 12-15 parts of medlar , 8-12 parts of black currant, 7-15 parts of Houttuynia cordata, 5-10 parts of rhodiola rosea, 3-8 parts of poria cocos, 5-10 parts of tangerine peel, 6-10 parts of hawthorn, 3-6 parts of astragalus, 5 parts of chuanxiong ～10 parts, 3～8 parts of Atractylodes macrocephala.

The pharmacological action of each raw material among the present invention is as follows:

Red raspberry: rich in vitamin A, vitamin C, calcium, potassium, magnesium and other nutrients as well as a lot of fiber, which can effectively relieve angina pectoris and other cardiovascular diseases, rich in salicylic acid, phenolic acid and other substances, can effectively protect Heart, prevent cardiovascular and cerebrovascular diseases such as high blood pressure, atherosclerosis of blood vessel wall, embrittlement and rupture of cardiovascular and cerebrovascular vessels.

Blackberry: Rich in vitamin C, especially the tanned acid contained in it has been proven to be the most effective substance for preventing cancer. Black raspberry seeds have the functions of enhancing immunity, promoting the growth of hematopoietic red blood cells, preventing hardening of human arteries and bones and joints, and promoting metabolism. .

Mulberry: The fatty acid contained in it can decompose fat, reduce blood fat, and prevent vascular sclerosis, etc. The black hair contained in mulberry seed can make hair black and shiny. Mulberry seeds can improve the skin, including the blood supply of the scalp, nourish the skin, make the skin white and tender, black hair, etc., and can delay aging. Mulberry seeds have immune-boosting effects and can prevent and fight cancer. Mulberry seeds can improve eyesight and relieve eye fatigue and dryness. It is especially suitable for those with deficiency of Yin and blood in the liver and kidney, those with gray hair in teenagers, and those who are physically weak, weak, and habitually constipated after illness.

Lycium barbarum: Contains betaine, atropine, and hyoscyamine. It has the effects of promoting immunity, anti-aging, anti-tumor, scavenging free radicals, anti-fatigue, anti-radiation, protecting liver, protecting and improving reproductive functions, etc. Betaine has a metabolic or anti-fatty liver effect on lipids. The carotenoids contained in wolfberry have very important medicinal value. Many studies have proved that wolfberry has the functions of improving human immune function, preventing and inhibiting tumors and preventing atherosclerosis.

Black currant: It is very rich in vitamin C, phosphorus, magnesium, potassium, calcium, anthocyanins, and phenolic substances. It has a variety of health-preserving effects, such as strengthening the gums, protecting the liver, improving visual function, anti-aging, nourishing blood and qi, especially the polyunsaturated fatty acids in black currant seeds also have a good effect on protecting the cardiovascular and cerebrovascular.

Houttuynia cordata: It contains volatile oil components such as houttuyniatin, lauric aldehyde, methyl n-nonyl ketone, balsamic vinyl, quercetin, and adenine, which are effective against Staphylococcus aureus, Staphylococcus albus, Shigella, Pseudomonas Bacillus, Proteus, Escherichia coli, Gram-positive bacillus, etc. all have certain inhibitory effects, and have stronger effects on Staphylococcus aureus and Staphylococcus albus. Neohouttuyfotin can promote tissue regeneration and has inhibitory effect on Ehrlich ascites carcinoma.

Rhodiola: Some reports point out that Rhodiola has anti-cancer and anti-mutation capabilities. Its anti-cancer mechanism lies in the control of cell growth cycle and apoptosis. A 2006 study pointed out that Rhodiola can inhibit the division process of HL-60 blood cancer cells and reduce their chances of survival. In addition, Rhodiola can directly inhibit the growth and spread of lung cancer cells.

Poria cocos: Poria cocos polysaccharide itself has no anti-tumor effect, but pachycos polysaccharide (ie pachyphyllin) and carboxymethyl pachymane polysaccharide have effects on mouse sarcoma S180 solid type and ascites-transformed solid type, cervical cancer S14 solid-type and ascites-transformed solid type. Types and so on have different degrees of anti-tumor effect. Carboxymethylpachysan has a strong inhibitory effect on transplanted tumor U14 in mice; it also has a certain inhibitory effect on Ehrlich ascites carcinoma. Experiments have shown that carboxymethyl pachymane can inhibit the DNA synthesis of Ehrlich ascites cancer cells. Poria cocos polysaccharide has inhibitory effect on mouse sarcoma S180, and the inhibition rate reaches 96.88%. Poria polysaccharides F1 and H11 have obvious antitumor activity.

Tangerine peel: Alcohol extracts can excite the myocardium, and it can also cause mild contraction of blood vessels and rapidly increase blood pressure. The pectin in tangerine peel also has a certain preventive effect on arteriosclerosis caused by high-fat diet.

Hawthorn: The main component of hawthorn is flavonoids, which have obvious pharmacological effects on the cardiovascular system. At present, there are more than 30 kinds of flavonoids isolated from hawthorn, mainly including flavonoid glycosides containing carbon bonds, flavonols and their glycosides, dioxyflavone glycosides, and polymerized flavonoids. Another important component is triterpenes, which have important functions such as strengthening the heart, increasing coronary blood flow, and improving blood circulation. In addition, hawthorn contains organic acids such as chlorogenic acid, caffeic acid and tannins, tannins, epicatechin, choline, acetylcholine, β-sitosterol, carotene and a large amount of Vit C, etc. Compounds such as vitexin contained in hawthorn have anti-cancer effects, and commonly used hawthorn is beneficial to cancer prevention. Experiments have shown that the water decoction of hawthorn slices can prolong the lifespan of animals with tumors, for example, it can inhibit the effect of Ehrlich ascites cancer cells in mice, and the inhibition rate of human cervical cancer TCC-26 can reach 70%.

Astragalus: It can significantly increase the total number of white blood cells in the blood, and promote the phagocytosis and bactericidal ability of neutrophils and macrophages. Astragalus can significantly enhance cellular immunity and promote lymphocyte transformation caused by PHA, COnA, and PWM (Pokeweed). Astragalus polysaccharides can increase the specific volume of red blood cells in normal rats and increase the number of red blood cells. Astragalus can also prevent the reduction of the total number of peripheral blood leukocytes and bone marrow nucleated cells in mice caused by radiation, and can promote the differentiation and proliferation of hematopoietic stem cells.

Chuanxiong: Chuanxiong has inhibitory effects on large intestine, dysentery (Sonnei), deformation, pus aeruginosa, typhoid fever, paratyphoid bacillus and Vibrio cholerae. Chuanxiong water extract (1:3) also has inhibitory effect on some pathogenic skin fungi in test tube. The water-soluble crude preparation of Chuanxiong Rhizoma Rhizoma Chuanxiong has protective effect on radiation exposure and nitrogen mustard injury in rats, mice and dogs. The anti-radiation effect of Rhizoma Chuanxiong on rats is better than that on mice, the effect of ip administration is better than that of im administration, and the effect of im administration is better than that of ig.

Atractylodes macrocephala: It has the effect of dilating blood vessels. It has an inhibitory effect on the heart, and the neutral oil in the volatile oil of Atractylodes Rhizoma Atractylodes Rhizome has obvious inhibitory effect on esophageal cancer cells. At 10mcg/ml, all cancer cells can be shed within 24 hours. At 5mcg/ml, most of the cancer cells can fall off, and the remaining small pieces of cells or scattered cells show nuclear pyknosis, blurred nucleoli, and many vacuoles in the vesicles. Atractylodes volatile oil 50-100mg/kg intraperitoneal injection has a significant inhibitory effect on Ehrlich ascites carcinoma. When administered systemically, efficacy against solid solid cancers has been inconsistently reported. When screening 358 kinds of herbal medicines, traditional Chinese medicine single prescriptions and compound prescriptions, Atractylodes macrocephala volatile oil has the strongest inhibitory effect on mouse sarcoma-180 (inhibition rate is 31-49%). Another report has S-180, S-37, U- 14 and W-256, as well as the leukemia model (L615) had no significant effect. Recently, it was reported that the neutralization activity of Atractylodes macrocephala on methA tumors was significantly higher than that of the control group, and significantly enhanced the delayed hypersensitivity of MethA tumors, and also promoted plant hemocytes Lectin-P and lipopolysaccharide-induced juvenile response.

The preparation method of the health product with anti-radiation effect of the present invention is specifically carried out according to the following steps:

Step 1, weigh 20-30 parts of red raspberry, 15-25 parts of blackberry, 10-20 parts of mulberry, 12-15 parts of medlar, 8-12 parts of black currant, 7-15 parts of Houttuynia cordata, Rhodiola rosea 5-10 parts, 3-8 parts of Poria cocos, 5-10 parts of tangerine peel, 6-10 parts of hawthorn, 3-6 parts of astragalus, 5-10 parts of Chuanxiong, 3-8 parts of Atractylodes macrocephala, add 8-15 times of water to soak Decoct 3 times, separate the liquid medicine;

Step 2, coarsely filter the medicinal liquid decocted for 3 times in step 1, mix the filtrate, cool and stand for 2 to 4 hours, and take the supernatant;

Step 3, take the supernatant obtained in step 2, add methylparaben powder according to the ratio of 5g methylparaben per 1kg solution, stir while adding, mix well, and let it stand for 3 to 6 hours , filter with filter cloth;

Step 4, sterilizing, disinfecting and packaging the filtrate obtained in step 3 to make an oral liquid preparation.

In the above step 1, soak in water for 3 to 6 hours; decoct for 1.5 to 2.5 hours each time.

In the above step 2, the filtrate is cooled to 15°C-25°C.

Example 1

Step 1. Weigh 25 parts of red raspberry, 20 parts of blackberry, 15 parts of mulberry, 13 parts of medlar, 10 parts of black currant, 11 parts of Houttuynia cordata, 5 parts of rhodiola rosea, 5 parts of poria cocos, 8 parts of tangerine peel, hawthorn 8 parts, 4 parts of Radix Astragali, 7 parts of Rhizoma Chuanxiong, 5 parts of Atractylodes Rhizome, add 10 times of water to soak for 4.5 hours, then decoct 3 times, each time for 2 hours, separate the liquid medicine;

Step 2, coarsely filter the medicinal liquid decocted for 3 times in step 1, mix the filtrate, cool to 20°C and let it stand for 3 hours, and take the supernatant;

Step 3, take the supernatant obtained in step 2, add methylparaben powder according to the ratio of adding 5g methylparaben per 1kg solution, stir while adding, fully mix, after standing for 5 hours, use filter cloth filter;

Step 4, sterilizing, disinfecting and packaging the filtrate obtained in step 3 to make an oral liquid preparation.

Example 2

Step 1. Weigh 20 parts of red raspberry, 15 parts of blackberry, 10 parts of mulberry, 12 parts of medlar, 8 parts of black currant, 7 parts of Houttuynia cordata, 5 parts of Rhodiola rosea, 3 parts of poria cocos, 5 parts of tangerine peel, hawthorn 6 parts, 3 parts of Radix Astragali, 5 parts of Rhizoma Chuanxiong, 3 parts of Atractylodes Rhizome, add 8 times the amount of water to soak for 3 hours, then decoct 3 times, each time for 1.5 hours, separate the liquid medicine;

Step 2, coarsely filter the medicinal liquid decocted for 3 times in step 1, mix the filtrate, cool to 15°C and let it stand for 2 hours, and take the supernatant;

Step 3, take the supernatant obtained in step 2, add methylparaben powder according to the ratio of adding 5g methylparaben per 1kg solution, stir while adding, fully mix, after standing for 3 hours, use filter cloth filter;

Step 4, sterilizing, disinfecting and packaging the filtrate obtained in step 3 to make an oral liquid preparation.

Example 3

Step 1. Weigh 30 parts of red raspberry, 25 parts of blackberry, 20 parts of mulberry, 15 parts of medlar, 12 parts of black currant, 15 parts of Houttuynia cordata, 10 parts of Rhodiola rosea, 8 parts of poria cocos, 10 parts of tangerine peel, hawthorn 10 parts, 6 parts of Radix Astragali, 10 parts of Rhizoma Chuanxiong, 8 parts of Atractylodes Rhizome, add 15 times the amount of water to soak for 6 hours, then decoct 3 times, decoct for 205 hours each time, and separate the liquid medicine;

Step 2, coarsely filter the medicinal liquid decocted for 3 times in step 1, mix the filtrate, cool to 25°C and let it stand for 4 hours, and take the supernatant;

Step 3, take the supernatant obtained in step 2, add methylparaben powder according to the ratio of adding 5g methylparaben per 1kg solution, stir while adding, fully mix, after standing for 6 hours, use filter cloth filter;

Step 4, sterilizing, disinfecting and packaging the filtrate obtained in step 3 to make an oral liquid preparation.

A kind of pharmacodynamics test and the result of the health product with anti-radiation effect of the present invention are as follows:

Step 1, animal treatment: After the experimental animals were fed adaptively for one week, groups A and B were not given any treatment, group C was given a mixture of vitamin E (30mg/kg) and vitamin C (50mg/kg), and group D was given compound raspberry seeds Powder (1.25g/kg) was administered into the stomach, and the drugs in groups C and D were dissolved to 2ml with normal saline, and the drugs were continuously administered for 7 days, with free drinking and eating;

Step 2, establishment of animal model: B, C, and D rats were irradiated with X-ray whole body 1 hour after gavage on the 7th day, the total dose was 8Gy, the dose rate was 400cGy/min, and the source-to-skin distance was 100cm. Rat model of acute radiation injury;

Step 3, blood sample collection: fasting after radiation, anesthetized with 10% chloral hydrate after 24 hours, take 5ml of blood from abdominal aorta, add it to heparin sodium anticoagulant tube, mix well, separate lymphocytes from 35ul whole blood for DNA damage analysis , 1ml of whole blood was used for GSH-PX activity determination, and the remaining whole blood was centrifuged to obtain plasma and stored in a -20°C refrigerator for later use;

Step 4, determination of SOD and GSH-PX indexes: serum SOD activity is measured by WST-1 method, and the wavelength of microplate reader is 450nm; whole blood GSH-PX enzyme activity is measured by colorimetric method with wavelength of 412nm;

Step 5, detection and analysis of DNA damage: the nuclei of normal lymphocytes should be large, round, and bright. According to the different degrees of damage to the nuclei, a "comet" image can appear after fluorescent staining. The "comet" image includes the head and tail According to the ratio of the two, it is divided into five grades: 0, I, II, III, and IV. Grade 0 has no tail, just a bright round nucleus, indicating no damage to the DNA. When the degree of DNA breakage and damage ranges from mild to severe, the tail of the comet gradually becomes longer and larger, the head becomes smaller and the fluorescence intensity gradually becomes weaker. Count 100 cells for each sample, calculate the AU value and perform statistical analysis to obtain the overall level of DNA damage;

Step 6, statistical processing: SPSS 21.0 statistical software was used for statistical analysis, and the data were expressed as mean ± standard deviation One-way analysis of variance was used for comparison between groups.

Experimental results:

1. Rats included in the experiment: 1 rat in group B died within 24 hours after radiation. After abdominal dissection, it was found that the intestinal cavity was dilated, flatulent, and mucous membrane hyperemia. The cause of death was considered to be radiation enteritis, a complication of radiotherapy.

2. The comparison of plasma SOD and whole blood GSH-PX activity values is shown in Table 1. From Table 1, it can be seen that compared with the blank control group, the SOD activity in the simple irradiation group was significantly reduced (P<0.01), and the GSH-PX activity was statistically significant (P<0.01). PX activity decreased, with statistical significance (P<0.05); compared with simple irradiation group, SOD activity of vitamin combination group and compound raspberry seed powder group both increased, with statistical significance (P<0.05), GSH- The activity of PX increased, which was statistically significant (P<0.05).

Table 1 Comparison of SOD and GSH-PX activity of rats in each group

Note: Compared with blank control group, *P<0.01; compared with blank control group, #P<0.05; compared with simple irradiation group, &P<0.05

The analysis of DNA damage in lymphocytes is shown in Figure 1 and Figure 2. It can be seen from Figure 1 that compared with the blank control group, the DNA damage of lymphocytes in the simple irradiation group was more serious, which was statistically significant (*P<0.05); compared with the simple control group, the combination of vitamins and compound raspberry seed powder The DNA damage of lymphocytes in the group was less severe, which was statistically significant (#P<0.05). It can be seen from Figure 2 that compared with the blank control group (Figure 2A), the DNA of lymphocytes in the simple irradiation group was severely damaged, and the tail of the comet was extended (Figure 2B), and the combination of vitamins (Figure 2C) and the compound raspberry seed powder group (Figure 2B) 2D) DNA damage in lymphocytes is mild.

Experiments have proved that this formula has anti-oxidation function and can enhance the vitality of SOD and GSH-PX. In general, this formula has the effects of anti-oxidation, anti-radiation and anti-tumor. The hematopoietic system is one of the systems most sensitive to radiation, which is manifested in the decrease in the number of white blood cells, red blood cells, and platelets in peripheral blood. The experimental results show that preventive use of compound raspberry seed powder can effectively improve the damage of radiation to the hematopoietic system. In this experiment, comet assay was used to evaluate the degree of DNA damage in lymphocytes. Whether it is through statistical calculation or naked eye observation under a microscope, it can be clearly observed that vitamins and compound raspberry seed powder are excellent in protecting the damage effect of radiation on lymphocyte DNA.

The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the protection scope of the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present invention are included in the protection scope of the present invention.

Claims (4)

1. A health care product with anti-radiation effect, characterized in that, it is formed by the proportioning of the following raw materials by weight: 20-30 parts of red raspberry, 15-25 parts of blackberry, 10-20 parts of mulberry, wolfberry 12-15 parts, black currant 8-12 parts, houttuynia cordata 7-15 parts, rhodiola rosea 5-10 parts, poria cocos 3-8 parts, tangerine peel 5-10 parts, hawthorn 6-10 parts, astragalus 3-6 parts 5-10 parts of Rhizoma Chuanxiong, 3-8 parts of Atractylodes Rhizoma. 2. the preparation method of the health care product with anti-radiation effect, is characterized in that, specifically carries out according to the following steps: Step 1, weigh 20-30 parts of red raspberry, 15-25 parts of blackberry, 10-20 parts of mulberry, 12-15 parts of medlar, 8-12 parts of black currant, 7-15 parts of Houttuynia cordata, Rhodiola rosea 5-10 parts, 3-8 parts of Poria cocos, 5-10 parts of tangerine peel, 6-10 parts of hawthorn, 3-6 parts of astragalus, 5-10 parts of Chuanxiong, 3-8 parts of Atractylodes macrocephala, add 8-15 times of water to soak Decoct 3 times, separate the liquid medicine; Step 2, coarsely filter the medicinal liquid decocted for 3 times in step 1, mix the filtrate, cool and stand for 2 to 4 hours, and take the supernatant; Step 3, take the supernatant obtained in step 2, add methylparaben powder according to the ratio of 5g methylparaben per 1kg solution, stir while adding, mix well, and let it stand for 3 to 6 hours , filter with filter cloth; Step 4, sterilizing, disinfecting and packaging the filtrate obtained in step 3 to make an oral liquid preparation. 3. The preparation method of the health care product with anti-radiation effect according to claim 2, characterized in that, in step 1, soak in water for 3-6 hours; decoct for 1.5-2.5 hours each time. 4. The preparation method of health products with anti-radiation effect according to claim 2, characterized in that, in step 2, the filtrate is cooled to 15°C-25°C.