CN107281630B - A Balloon Particle Cannula System for Treating Esophageal Cancer - Google Patents

Abstract

The invention relates to a balloon particle casing system for treating esophageal cancer. A nutrient solution injection connector and a nutrient tube are provided with a nutrient solution injection channel that communicates with an inner hole of the nutrient tube, and the outer end of the nutrient solution injection connector is provided with a nutrient solution. The nutrient solution injection joint is connected with the reinforced connection table through the rotating table, the reinforcement connection table is connected with the nutrition tube, and a balloon particle sleeve device is arranged on the outer wall of the nutrition tube; the adhesion between the inner wall tissues of the skin is avoided. , effectively maintaining the high-efficiency effect of radioactive particles, realizing rotation and expansion, high concentration, and improving the overall drug delivery and the efficacy of direct targeting of the lesions.

Description

A Balloon Particle Cannula System for Treating Esophageal Cancer

technical field

The invention relates to a medical device, in particular to a balloon particle cannula system for treating esophageal cancer.

Background technique

Esophageal cancer is a common digestive tract tumor. The typical symptom of esophageal cancer is progressive dysphagia. The early symptoms are often not obvious, but there may be different degrees of discomfort when swallowing hard food, including choking feeling after swallowing food, retrosternum. Burning, acupuncture, or pulling and friction-like pain, the symptoms range from mild to severe, and the patient's quality of life decreases. With the increase of tumor cancer, the first is difficult to swallow dry food, then semi-liquid food, and finally water and saliva cannot be swallowed. The treatment methods for esophageal cancer include surgery, radiotherapy and chemotherapy. If the general condition is good, there is good cardiopulmonary function reserve, and there is no obvious sign of distant metastasis, radical surgery can be considered. However, in most cases in China, or when visiting a doctor, the tumor often invades multiple organs locally and loses the opportunity for radical surgery, and can only choose palliative radiotherapy and chemotherapy. The traditional discharge cycle is long, and complications such as esophageal perforation, fistula, radiation pneumonitis, and esophageal stricture are prone to occur. For patients with inability to eat, palliative esophageal stent implantation is often the only option, but esophageal stents can only open esophageal strictures and have no therapeutic effect on tumors.

Radioactive ¹²⁵ I particles are a short-range nuclide used for the treatment of malignant tumors and are currently widely used in clinical practice. At present, a new treatment method has emerged, that is, using a special method to coat radioactive particles on the esophageal stent to form a brachytherapy stent. After the stent is implanted, not only can the esophageal stricture be opened, but also the continuous low-dose irradiation function of 125I radioactive particles can be exerted, thereby treating malignant tumors of the esophagus. This method has greatly improved the effect of treatment, and played a role of killing two birds with one stone. However, this treatment method has some clinical defects, which are manifested as follows: first, the grid structure, and its frame structure criss-crosses the trunk support body is thin, mostly diamond-shaped holes or rectangular hole mesh structure, in the role of After the lesion, under the action of long-term support and expansion, the mesh is easily combined with the skin tissue, and the granulation tissue proliferates, resulting in the stent re-stenosis. Secondly, if the tumor is very sensitive to brachytherapy, and the tumor shrinks significantly in a short period of time, the residual particle radiotherapy dose will damage normal tissues, leading to the possibility of related complications. Third, esophageal tumors tend to grow heterogeneously within the lumen, but the dose coverage of esophageal particle stents is cylindrical, and the dose received by the tumor is not uniform. Fourth, esophageal seed stent implantation is only palliative treatment, and after stent implantation, the stent cannot be removed. Fifth, if the esophageal seeds are displaced after implantation, it means the displacement of the particle dose. Not only the radionuclide cannot accurately perform brachytherapy on esophageal tumors, but also radiation damage to the normal esophageal wall is easy to occur after the displacement. Sixth, due to the limitation of the coating process, the radiation particles are mostly scattered and irregularly distributed on the traditional stent-graft. During the stent implantation process, due to the irregular shape of the lesion location, even within the same cutting layer loop, It is also divided into different shapes. Some places are serious, some are lighter, and serious parts require more radiation particles. It is difficult for traditional particle stents to achieve symptomatic distribution, and different densities of particles are applied according to their distribution parts. The overall treatment is unstable, and more serious parts cannot be effectively treated.

Therefore, to provide a treatment with simple structure, convenient operation, high work and operation efficiency, stable operation, favorable for popularization and promotion, effectively alleviating the pain of patients, convenient installation and disassembly, obvious effect, differentiated treatment, and overall stable and targeted treatment Balloon particle cannula system for esophageal cancer has broad market prospects.

SUMMARY OF THE INVENTION

Aiming at the deficiencies of the prior art, the present invention provides a simple structure, convenient operation, high work and operation efficiency, stable operation, favorable for popularization and promotion, effectively alleviating the pain of patients, convenient installation and disassembly, obvious effect, differentiated treatment, The balloon particle cannula system for treating esophageal cancer with overall stability and strong targeting is used to solve the deficiencies of the prior art.

The technical solution of the present invention is achieved as follows: a balloon particle cannula system for treating esophageal cancer, comprising a nutrition tube, an inner hole of the nutrition tube arranged on one side of the nutrition tube, and a first marker arranged at one end of the nutrition tube layer, a nutrient solution injection connector arranged on the other side of the nutrient tube, an injection push rod installed in the nutrient solution injection connector, the nutrient solution injection connector and the nutrient tube are provided with a nutrient solution that communicates with the inner hole of the nutrient tube The liquid injection channel, the outer end of the nutrient liquid injection connection head is provided with a nutrient liquid injection reinforcement port, the nutrient liquid injection connection head is connected with the reinforcement connection table through the rotary table, and the reinforcement connection table is connected with the nutrition tube. A balloon particle cannula device is arranged thereon.

The balloon particle casing device comprises an inner air bag sleeved on the outer wall of the nutrient tube, an outer capsule film is sleeved on the outer side of the inner air bag, and a radioactive particle limiting tube is installed between the outer capsule film and the inner air bag, and the radioactive particle restricting tube is installed. The position tube is filled with radioactive particles, the inner airbag is connected with the airbag inflation port through an inflation pipeline, and a second marking layer is arranged on the nutrition tube inside the inner airbag.

The balloon particle casing device is arranged on the nutrition tube between the strengthening connection platform and the inner hole of the nutrition tube, the strengthening connection platform is a cylindrical hollow casing structure, and the inner wall of the strengthening connection platform and the outer wall of the nutrition tube are The way of pasting is fixedly connected, and the outer side of the strengthening connection table is fixedly connected to the inner side of the rotary table through the method of pasting. The inner side of the injection connector is connected by sticking, and the nutrient solution injection reinforcement port is pasted on the outer side of the nutrient solution injection connector.

The strengthening connection table, the rotating table, the nutrient solution injection strengthening port and the nutrient solution injection connecting head are integrated into one structure, and anti-skid grooves are evenly arranged on the outer wall of the rotating table. The diameter of the platform is not less than the diameter of the strengthening connection platform, the diameter of the nutrient solution injection connector is not larger than the diameter of the nutrient tube, and the diameter of the nutrient solution injection strengthening port is equal to the diameter of the nutrient tube.

The inner air bag is connected with the inflation pipe through the inflation port, the inflation pipe is arranged on the inner side of the nutrient tube, the inflation port is opened on the outer wall of the inner nutrient tube, one end of the inflation port is communicated with the inner side of the inner air bag, and the other side of the inflation port is connected with the inner side of the inner air bag. One end is communicated with the inflation port of the air bag, the inner air bag is sheathed on the outer wall of the nutrition tube by means of pasting, and the outer bag membrane is arranged on the tube wall of the nutrition tube outside the inner air bag by means of pasting.

The airbag inflation port is installed on the outside of the nutrient solution injection connector, the airbag inflation port is communicated with the inflation pipeline, and the outer wall of the nutrient solution injection connector and the outer wall of the airbag inflation port are fixedly connected by sticking.

There are two second marking layers, the two second marking layers are arranged at both ends of the nutrition tube inside the inner airbag, and edge radioactive particle tubes are arranged at both ends of the radioactive particle limiting tube, and the edge radioactive particle tubes are filled with There are radioactive particles in edge locations.

The cross section of the outer capsule is a wavy annular structure, and the outer side of the outer capsule is provided with a wave-shaped limiting groove.

The present invention has the following positive effects: the product has a simple structure and is easy to operate. First, by using this product, it is possible to avoid the adhesion between the traditional grid-structured stent and the inner wall of the skin after being removed from the shelf, and to avoid secondary problems caused by long-term parking. The injury caused by the pulling operation reduces the pain of the patient, and the outer capsule structure is used, which has a long service life and has not changed. Follow-up medical work; secondly, this product realizes real-time mobile positioning with the change of the position of the lesion. The product is set with multiple marking layers. After positioning, it can rotate and expand through the rotary table, and realize rotation, lateral movement and vertical movement in relative positions. , and the efficient combination greatly improves the treatment effect; thirdly, the radiation particle structure of this product adopts a suit type, and the efficient collection and regular planning are fixed. Distinguish between severe and mild symptoms and treat the way out. Within the same cutting layer loop line, or on different working surfaces of longitudinal depths, it is effective to work on symptoms of different mild degrees, and apply particle layouts of different densities according to their distribution positions, which greatly improves the It improves the stability and high-efficiency effect, and improves the overall drug delivery and the drug effect directly targeting the lesions.

Description of drawings

FIG. 1 is a schematic structural diagram of an embodiment of the present invention.

FIG. 2 is a schematic structural diagram of another embodiment of the present invention.

FIG. 3 is a schematic diagram of the internal structure of the present invention.

FIG. 4 is a schematic diagram of a partial cross-sectional structure of FIG. 1 of the present invention.

FIG. 5 is a schematic diagram of a partial cross-sectional structure of FIG. 2 of the present invention.

Detailed ways

As shown in Figures 1, 2, 3, 4, and 5, a balloon particle cannula system for the treatment of esophageal cancer includes a feeding tube 1, a feeding tube inner hole 3 disposed on one side of the feeding tube 1, and a feeding tube 3 disposed on the feeding tube 1 The first marking layer 2 at one end, the nutrient solution injection connector 13 arranged on the other side of the nutrient tube 1, the injection push rod 15 installed in the nutrient solution injection connector 13, the nutrient solution injection connector 13 and the nutrient tube 1 are provided with a nutrient solution injection channel 18 that communicates with the inner hole 3 of the nutrient solution tube. 10 is connected with the strengthening connection platform 9, the strengthening connection platform 9 is connected with the nutrition tube 1, and a balloon particle casing device is arranged on the outer wall of the nutrition tube 1.

The described balloon particle cannula device comprises an inner air bag 5 sleeved on the outer wall of the nutrient tube 1, an outer bag membrane 4 is sleeved on the outer side of the inner air bag 5, and a radioactive particle limiter is installed between the outer capsule film 4 and the inner air bag 5. The position tube 6, the radioactive particle limiting tube 6 is filled with radioactive particles 7, the inner air bag 5 is connected with the air bag inflation port 12 through the inflation pipe 16, and the nutrition tube 1 inside the inner air bag 5 is provided with a second marking layer 8. The balloon particle casing device is arranged on the nutrition tube 1 between the strengthening connection platform 9 and the inner hole 3 of the nutrition tube. The strengthening connection platform 9 is a cylindrical hollow casing structure. The outer wall of the nutrition tube 1 is fixedly connected by means of sticking, and the outside of the strengthening connection table 9 is fixedly connected with the inside of the rotary table 10 by means of sticking. The outer side of the rotary table 10 is connected with the inner side of the nutrient solution injection connector 13 by sticking, and the nutrient solution injection reinforcement port 14 is attached to the outer side of the nutrient solution injection connector 13 . The reinforced connection table 9, the rotary table 10, the nutrient solution injection reinforcement port 14 and the nutrient solution injection connection head 13 are integrated into one structure, and the outer wall of the rotary table 10 is evenly provided with anti-skid grooves 11, and the diameter of the reinforcement connection table 9 is different. Smaller than the diameter of the nutrient tube 1, the diameter of the rotary table 10 is not less than the diameter of the strengthening connection table 9, the diameter of the nutrient solution injection connector 13 is not larger than the diameter of the nutrient tube 1, and the diameter of the nutrient solution injection reinforcement port 14 is the same as the diameter of the nutrient solution injection tube 1. diameters are equal.

The inner air bag 5 is connected with the inflation pipe 16 through the inflation port 17. The inflation pipe 16 is arranged on the inner side of the nutrition tube 1. The inner side of the nutrient tube 1 is connected to each other, the other end of the inflation port 17 is communicated with the air bag inflation port 12, the inner air bag 5 is set on the outer wall of the nutrition tube 1 by pasting, and the outer bag membrane 4 is installed by pasting the nutrition outside the air bag 5. on the wall of tube 1. The airbag inflation port 12 is installed on the outside of the nutrient solution injection connector 13, the airbag inflation port 12 is communicated with the inflation pipeline 16, and the outer wall of the nutrient solution injection connector 13 and the outer wall of the airbag inflation port 12 are fixedly connected by sticking. . The number of the second marking layers 8 is two, the two second marking layers 8 are arranged at both ends of the nutrition tube 1 inside the inner balloon 5 , and edge radioactive particle tubes 19 are arranged at both ends of the radioactive particle limiting tube 6 . , the edge radioactive particle tube 19 is filled with radioactive particles 20 at the edge position. The cross section of the outer capsule 4 is a wavy annular structure, and the outer side of the outer capsule 4 is provided with a wave-shaped limiting groove.

When using this product, for patients with esophageal cancer, firstly, the bottom end of the feeding tube 1 is introduced into the patient's esophagus to ensure that the inner hole 3 of the feeding tube at the bottom is unobstructed, and is lowered to the lower side of the cancer cell tumor to maintain a continuous unobstructed supply. liquid. When it is lowered, it is marked by the first marking layer 2, which is an X-ray opaque substance, which plays a very good role in marking. At the same time, the second marker layer 8 is also an X-ray opaque material. When the outer capsule 4 is lowered, it is ensured that the lower position of the outer capsule 4 is exactly aligned with the position of the cancer cell cyst, and the double second marker layers 8 are used for positioning with high accuracy. When the radioactive particles are applied, they can act in stages from high to low. The inner wall of the cancer cell cyst is irregular in shape. The inner balloon is used to fill the gas and then the saturated state is stretched to ensure that the outer capsule 4 is tightly combined with the inner wall of the tumor, and at the same time, the outer capsule 4 The cross section of the outer capsule 4 is a wave-shaped annular structure, and the outer side of the outer capsule 4 is provided with a wave-shaped limiting groove, which helps to help the outer capsule 4 and the inner wall of the tumor to be highly fitted, and ensures the efficacy of the radioactive particles 7 to play.

Chen Pin designs two implementations. In another implementation, edge radioactive particle tubes 19 are provided at both ends of the radioactive particle limiting tube 6 , and the edge radioactive particle tubes 19 are filled with edge radioactive particles 20 . During the specific operation, it will be found that if the longitudinal length of the outer capsule 4 of the product is smaller than the longitudinal length of the tumor, the inner wall of the tumor will be squeezed after inflation, and the tumor will wrap the outer capsule 4 as a whole. implementation of treatment.

During the overall treatment period, to complete a cycle of treatment, the relative position movement can be completed by moving or rotating the rotary table 10, so as to realize the up and down movement, the rotation movement at the same position, etc. At the same time, targeted treatment can be carried out according to the severity of the tumor inner wall, which greatly improves the treatment effect.

Claims (6)

1. The utility model provides a sacculus particle bushing system of treatment esophagus cancer, includes nutrition tube (1), sets up at nutrition tube inner hole (3) of nutrition tube (1) one side, sets up at first mark layer (2) of nutrition tube (1) one side tip, sets up at nutrition liquid injection connector (13) of nutrition tube (1) opposite side, installs injection push rod (15) in nutrition liquid injection connector (13), its characterized in that: nutrient solution injection channels (18) communicated with the inner hole (3) of the nutrient tube are arranged in the nutrient solution injection connector (13) and the nutrient tube (1), a nutrient solution injection reinforcing port (14) is arranged at the outer side end of the nutrient solution injection connector (13), the nutrient solution injection connector (13) is connected with a reinforcing connection table (9) through a rotary table (10), the reinforcing connection table (9) is connected with the nutrient tube (1), and a balloon particle sleeve device is arranged on the outer wall of the nutrient tube (1); the balloon particle sleeve device comprises an inner balloon (5) sleeved on the outer wall of a nutrition tube (1), an outer balloon membrane (4) is sleeved on the outer side of the inner balloon (5), a radioactive particle limiting tube (6) is installed between the outer balloon membrane (4) and the inner balloon (5), radioactive particles (7) are filled in the radioactive particle limiting tube (6), the inner balloon (5) is connected with a balloon inflation opening (12) through an inflation pipeline (16), and a second marking layer (8) is arranged on the nutrition tube (1) on the inner side of the inner balloon (5); the section of the outer sac membrane (4) is of a wave annular structure, and the outer side of the outer sac membrane (4) is provided with a wave-shaped limiting groove.

2. A balloon particle cannula system for treating esophageal cancer according to claim 1, wherein: sacculus particle bushing apparatus set up in nutrition pipe (1) between enhancement connection platform (9) and nutrition pipe inner bore (3), enhancement connection platform (9) be cylindrical hollow sleeve structure, the inner wall of enhancement connection platform (9) adopts the mode fixed connection of pasting with the outer wall of nutrition pipe (1), the inboard fixed connection of mode and revolving stage (10) through pasting in the outside of enhancement connection platform (9), the inboard of revolving stage (10) is provided with the through-hole, this through-hole is linked together with nutrient solution injection channel (18), the inboard of revolving stage (10) and nutrient solution injection connector (13) adopts the mode of pasting to be connected, nutrient solution injection enhancement mouth (14) are pasted in the outside of nutrient solution injection connector (13).

3. A balloon particle cannula system for treating esophageal cancer according to claim 1, wherein: strengthen connecting platform (9), revolving stage (10), nutrient solution pours into and strengthens mouth (14) and nutrient solution injection connector (13) structure as an organic whole, evenly be provided with antiskid groove (11) on the outer wall of revolving stage (10), strengthen the diameter of connecting platform (9) and be not less than the diameter of nutrient canal (1), the diameter of revolving stage (10) is not less than the diameter of strengthening connecting platform (9), the diameter of connector (13) is not more than the diameter of nutrient canal (1) is poured into to the nutrient solution, the diameter of strengthening mouth (14) is poured into to the nutrient solution and is equal with the diameter of nutrient canal (1).

4. A balloon particle cannula system for treating esophageal cancer according to claim 1, wherein: the inner air bag (5) is connected with an air charging pipeline (16) through an air charging port (17), the air charging pipeline (16) is arranged on the inner side of the nutrition tube (1), the air charging port (17) is arranged on the outer wall of the inner nutrition tube (1), one end of the air charging port (17) is communicated with the inner side of the inner air bag (5), the other end of the air charging port (17) is communicated with an air bag air charging port (12), the inner air bag (5) is sleeved on the outer wall of the nutrition tube (1) in a sticking mode, and an outer air bag film (4) is arranged on the tube wall of the nutrition tube (1) on the outer side of the inner air bag (5) in a sticking mode.

5. A balloon particle cannula system for treating esophageal cancer according to claim 1, wherein: the outer wall of the nutrient solution injection connector (13) is fixedly connected with the outer wall of the air bag inflation port (12) in a sticking mode.

6. A balloon particle cannula system for treating esophageal cancer according to claim 1, wherein: the number of the second marking layers (8) is two, the two second marking layers (8) are arranged at two ends of the nutrition tube (1) on the inner side of the inner air bag (5), edge radioactive particle tubes (19) are arranged at two ends of the radioactive particle limiting tube (6), and radioactive particles (20) at edge positions are filled in the edge radioactive particle tubes (19).

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