CN107412111A - A kind of oral cavity anti-inflammatory gargle - Google Patents
A kind of oral cavity anti-inflammatory gargle Download PDFInfo
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- CN107412111A CN107412111A CN201710833358.6A CN201710833358A CN107412111A CN 107412111 A CN107412111 A CN 107412111A CN 201710833358 A CN201710833358 A CN 201710833358A CN 107412111 A CN107412111 A CN 107412111A
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- oral cavity
- gargle
- inflammatory
- oral
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- 210000000214 mouth Anatomy 0.000 title claims abstract description 52
- 230000003110 anti-inflammatory effect Effects 0.000 title claims abstract description 36
- 239000000341 volatile oil Substances 0.000 claims abstract description 14
- 241000196324 Embryophyta Species 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 235000005979 Citrus limon Nutrition 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 9
- 229920001993 poloxamer 188 Polymers 0.000 claims description 8
- 229940044519 poloxamer 188 Drugs 0.000 claims description 8
- 244000248349 Citrus limon Species 0.000 claims 2
- CTKXFMQHOOWWEB-UHFFFAOYSA-N Ethylene oxide/propylene oxide copolymer Chemical group CCCOC(C)COCCO CTKXFMQHOOWWEB-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 20
- 235000002639 sodium chloride Nutrition 0.000 abstract description 18
- 239000004094 surface-active agent Substances 0.000 abstract description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract description 10
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract description 10
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract description 10
- 239000011780 sodium chloride Substances 0.000 abstract description 10
- 239000000811 xylitol Substances 0.000 abstract description 10
- 235000010447 xylitol Nutrition 0.000 abstract description 10
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract description 10
- 229960002675 xylitol Drugs 0.000 abstract description 10
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract description 9
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 abstract description 9
- 239000008367 deionised water Substances 0.000 abstract description 9
- 229910021641 deionized water Inorganic materials 0.000 abstract description 9
- 229940041616 menthol Drugs 0.000 abstract description 9
- 235000017166 Bambusa arundinacea Nutrition 0.000 abstract description 8
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- 241001330002 Bambuseae Species 0.000 abstract description 8
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract description 8
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- 235000015334 Phyllostachys viridis Nutrition 0.000 abstract description 8
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract description 8
- 239000011425 bamboo Substances 0.000 abstract description 8
- 150000003839 salts Chemical class 0.000 abstract description 8
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- 239000000576 food coloring agent Substances 0.000 abstract description 5
- 208000007565 gingivitis Diseases 0.000 abstract description 4
- 230000002265 prevention Effects 0.000 abstract description 4
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- 208000030194 mouth disease Diseases 0.000 abstract description 3
- 235000015165 citric acid Nutrition 0.000 abstract description 2
- 235000019441 ethanol Nutrition 0.000 abstract description 2
- 244000131522 Citrus pyriformis Species 0.000 description 19
- 230000000694 effects Effects 0.000 description 12
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical group C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 8
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- 206010006326 Breath odour Diseases 0.000 description 7
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- 230000001680 brushing effect Effects 0.000 description 6
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- 239000003921 oil Substances 0.000 description 5
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- 230000001408 fungistatic effect Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 208000006558 Dental Calculus Diseases 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 208000001705 Mouth breathing Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 206010040829 Skin discolouration Diseases 0.000 description 1
- 241000194019 Streptococcus mutans Species 0.000 description 1
- 241000193987 Streptococcus sobrinus Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
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- 238000005299 abrasion Methods 0.000 description 1
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- 230000000675 anti-caries Effects 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
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- 206010003246 arthritis Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000001013 cariogenic effect Effects 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
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- 238000011156 evaluation Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 208000021822 hypotensive Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 229940074869 marquis Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229920001992 poloxamer 407 Polymers 0.000 description 1
- 229940044476 poloxamer 407 Drugs 0.000 description 1
- VBUNOIXRZNJNAD-UHFFFAOYSA-N ponazuril Chemical compound CC1=CC(N2C(N(C)C(=O)NC2=O)=O)=CC=C1OC1=CC=C(S(=O)(=O)C(F)(F)F)C=C1 VBUNOIXRZNJNAD-UHFFFAOYSA-N 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 208000008655 root caries Diseases 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 201000010153 skin papilloma Diseases 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000037351 starvation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 210000004746 tooth root Anatomy 0.000 description 1
- 235000000112 undernutrition Nutrition 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of oral cavity anti-inflammatory gargle, its formula is made up of natural plant essential oils, surfactant, Mint Essence, menthol, food coloring, soda, sea salt, bamboo salt, citric acid, xylitol, ethanol and deionized water, anti-inflammatory gargle in oral cavity provided by the invention can prevention of gingivitis, reduce dental plaque, eliminate oral peculiar smell, and growing for oral cavity bacterium can be prevented, so as to effectively prevent various mouth diseases, used suitable for various people.
Description
Technical field
The invention belongs to daily chemicals technical field, and in particular to a kind of oral cavity anti-inflammatory gargle.
Background technology
With the continuous progress of society, people increasingly focus on self-image in contacts.Except dressing and talk
Outside manner, the smell for having been noted that in the mouth is also a part for self-image.It is universal that oral peculiar smell has become people in recent years
The topic spoken of.However, cause the main reason of halitosis to be a large amount of bacteriums in human mouth, these bacteriums decompose swill and
Protein in saliva, produce a variety of gases for having peculiar smell.The oxygen-containing sufficiently saliva of flowing can suppress bacterial reproduction and dissolve
These gases are diluted without producing obvious taste.There is mouth because night salivary secretion is reduced when from morning in many normal persons
It is smelly, but with feeding, gargle, excessive saliva and disappear.In addition, with advancing age, the flowing of saliva is gradually slack-off, because
This, the elderly has the worry of more halitosis than young man.Ethanol, starvation, excessive talk, nasal obstruction, during taking exercises
Any factor of dry is caused to produce halitosis with mouth breathing etc..In addition to halitosis, because teeth brushing way is incorrect, life
The various oral problems caused by reason, such as gingivitis, bacterial plaque, children's decayed tooth carious tooth, aged dental root caries such as work and rest irregular,
Also the quality of life of people is being affected.
The gargle class product of commercial type at present, most effect is single, and effect and unobvious.Therefore develop
The gargle that can prevent a variety of oral problems with extensive adaptability is significant.
The content of the invention
It is an object of the invention to provide a kind of oral cavity anti-inflammatory gargle, the gargle enough prevents the taste of oral cavity bacterium
It is long, so as to effectively prevent various mouth diseases, used suitable for various people.
The present invention is to be achieved through the following technical solutions：
A kind of oral cavity anti-inflammatory gargle disclosed by the invention, it is by percentage to the quality, composed of the following components：
Preferably, by percentage to the quality, it is composed of the following components：
Preferably, by percentage to the quality, it is composed of the following components：
Preferably, by percentage to the quality, it is composed of the following components：
Preferably, described natural plant essential oils are lemon.Preferably, described surfactant is poloxamer
407。
Preferably, described food coloring is lemon yellow.
Preferably, the water is deionized water.
Compared with prior art, the present invention has technique effect beneficial below：
Anti-inflammatory gargle in oral cavity provided by the invention, adds natural plant essential oils, Mint Essence, menthol and sea salt,
Can prevention of gingivitis, reduce dental plaque, eliminate oral peculiar smell, and growing for oral cavity bacterium can be prevented, so as to effective
Prevent various mouth diseases, used suitable for various people.Wherein adding surfactant has the function that to strengthen cleaning, adds thin
Lotus brain has the effect of refreshing oneself, restoring consciouness, may feel that the residue in oral cavity is cleaned out after use, tooth, teeth space become
Totally, have a kind of refrigerant sensation, then with tongue rub facing slightly on the strength a little swallowed, can feel very clean in oral cavity
Only, the mucus in oral cavity significantly reduces, and teeth space distributes a kind of refreshing cold air from inside to outside, makes us being in a cheerful frame of mind.It is this
Sensation can be kept for a very long time in oral cavity, make one spiritual straightforward, that is bored feels to be improved.Added in the present invention
Xylitol is the best sweetener of anti-caries, obtains certification in varied situations within the time of 25 years.Xylitol can subtract
This characteristic of few carious tooth, in high-risk rate crowd (carious tooth incidence height, Undernutrition, oral hygiene level are low) and low level of significance
It is applicable in crowd's (being taken care of one's teeth using current all cleaning of teeth measures, dental cavity generation rate is low).Added in the present invention
Sea salt there is the effect of bactericidal, it is rich in the necessary mineral matter of human body, and oral cavity can be made to produce more salivas, with lubrication
Food, favorably chew, swallow and digest, can also strengthen, the unsound tooth of remineralization, firm gum, functions of whitening teeth.Cause
This, the oral cavity anti-inflammatory gargle that above-mentioned formula is formed, has advantages below：
1. Efficient antibacterial --- to the inhibiting rate of harmful bacteria up to 99%, effectively safeguard that oral cavity flora balances；
2. fresh breath --- oral peculiar smell can be quickly eliminated, effectively prevention, alleviation halitosis, fresh breath；
3. cleaning is deeply --- the deep spot being hidden in teeth space can be quickly removed, gos deep into pharyngeal cleaning oral cavity comprehensively；
4. avoid wearing --- avoid brushing teeth the enamel abrasion brought, makes tooth brighter and cleaner；
5. avoid bleeding --- caused bleeding gums of brushing teeth are avoided, make oral cavity anti-virus ability stronger；
6. nursing is comprehensive --- sterilization is reached by a step of gargling, cleaned the teeth, permanent tooth effect.
Further, the natural plant essential oils added in anti-inflammatory gargle in oral cavity of the invention select lemon, have
Act on below：Improve Oily, skin lightening, whitening purifying skin, improve rupture capilary, remove old dead cell, except corn, flat
Wart；Stimulate circulation, mitigate varication；Hypotensive, improve anaemia；Mitigate headache, gout, arthritis；Anti-infective, sense
Emit, inflammation；Aid digestion, the clarification state of mind；Lemon has growth inhibition to common cariogenic bacteria such as streptococcus mutans, streptococcus sobrinus
Effect, and have scavenging action to free radical.
Brief description of the drawings
Fig. 1 is anti-inflammatory gargle in oral cavity disclosed by the invention to garlic flavour removal effect；
Fig. 2 is fungistatic effect figure of the anti-inflammatory gargle in oral cavity disclosed by the invention to different microorganisms.
Embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and
It is not to limit, embodiments of the invention not limited to this, for especially not dated technological parameter or condition, can refer to routine techniques
Carry out.
Anti-inflammatory gargle in oral cavity provided by the invention, it includes natural plant essential oils, surfactant, minty note in being formulated
Essence, menthol, food coloring, soda, sea salt, bamboo salt, citric acid, xylitol, ethanol and deionized water.Can prevention of gingivitis,
Reduce dental plaque, eliminate oral peculiar smell.
Preferably, surfactant uses poloxamer188, and natural plant essential oils use the fresh lemon within the shelf-life
Lemon essential oil, food coloring select lemon yellow.
Specifically, the weight/mass percentage composition of each component is as follows in anti-inflammatory gargle in oral cavity provided by the invention：
Natural plant essential oils (lemon) 0.0025%~0.003%, surfactant (poloxamer188)
0.001%th, Mint Essence 0.05%~0.1%, menthol 0.01%~0.015%, food coloring (lemon yellow)
0.000012%th, soda 0.01%, sea salt 0.1%~0.2%, bamboo salt 0.1%~0.2%, citric acid 0.002%, xylitol
0.0012%th, ethanol 0.15%, surplus are deionized water.
With reference to the present invention preferably embodiment, the present invention is described in further details.
Embodiment 1
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components：Natural plant essential oils (lemon extract
Oil) 0.0025%, it is surfactant (poloxamer188) 0.001%, Mint Essence 0.08%, menthol 0.012%, edible
Pigment (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.1%, bamboo salt 0.1%, citric acid 0.002%, xylitol
0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method：Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters,
Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 2
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components：Natural plant essential oils (lemon extract
Oil) 0.003%, surfactant (poloxamer188) 0.001%, Mint Essence 0.1%, menthol 0.015%, edible color
Plain (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.15%, bamboo salt 0.15%, citric acid 0.002%, xylitol
0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method：Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters,
Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 3
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components：Natural plant essential oils (lemon extract
Oil) 0.0026%, surfactant (poloxamer188) 0.001%, Mint Essence 0.09%, menthol 0.01%, edible color
Plain (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.2%, bamboo salt 0.2%, citric acid 0.002%, xylitol
0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method：Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters,
Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 4
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components：Natural plant essential oils (lemon extract
Oil) 0.0027%, it is surfactant (poloxamer188) 0.001%, Mint Essence 0.06%, menthol 0.013%, edible
Pigment (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.12%, bamboo salt 0.18%, citric acid 0.002%, xylitol
0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method：Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters,
Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
Embodiment 5
A kind of oral cavity anti-inflammatory gargle, it is by mass percentage, composed of the following components：Natural plant essential oils (lemon extract
Oil) 0.0028%, it is surfactant (poloxamer188) 0.001%, Mint Essence 0.05%, menthol 0.011%, edible
Pigment (lemon yellow) 0.000012%, soda 0.01%, sea salt 0.18%, bamboo salt 0.12%, citric acid 0.002%, xylitol
0.0012%th, ethanol 0.15%, surplus are deionized water.
Preparation method：Exemplified by configuring 100ml gargles, mentioned component is proportionally added in 90ml deionized waters,
Mix, then constant volume is packed to 100ml after sterilization with the special plastic bottle by disinfecting.
The effect of anti-inflammatory gargle in oral cavity provided by the invention is illustrated below.
1st, anti-inflammatory gargle in oral cavity eliminates garlic taste effect disquisition
7g mashed garlic is applied to blank sheet of paper center in a manner of rolling, the oral cavity anti-inflammatory gargle made from the embodiment of the present invention 1
Uniformly spray 3 times, blank sheet of paper is placed at dry shady and cool ventilation on blank sheet of paper central point, every 1min, evaluates garlicky concentration on blank sheet of paper,
The people of evaluation number 10.Initial garlicky concentration is designated as 100, is designated as 0 without garlicky, other take same time point more according to deep or light marking
People's marking average is the time point garlicky concentration score value, using the score value and the percentage of initial garlicky concentration as garlicky residual
Rate, residual rate are more low better.Residual rate result is as shown in figure 1, it can be seen from figure 1 that gargle described in the present embodiment can be in the short time
Garlic flavour is reduced to 50% or so, 7min or so and is completely removed garlic flavour by interior (about 1min), and is not added with any gargle
Blank sheet of paper (compare) on garlic taste still largely remained in 8min.This experiment demonstrates the gargle and removes having for garlic flavour
Effect property.
2nd, fungistatic effect is tested
By anti-inflammatory gargle in oral cavity made from the embodiment of the present invention 4 according to fungistatic effect test side described in GB15979-2002
Method is measured, and calculates bacteriostasis rate, as a result as shown in Figure 2.From figure 2 it can be seen that shield tooth in oral cavity produced by the present invention is gargled
Liquid is effective to staphylococcus aureus, Escherichia coli and candida albicanses, to staphylococcus aureus and Escherichia coli
Bacteriostasis rate is of a relatively high.
3rd, specifically used example
In order to verify the effect of the oral cavity anti-inflammatory gargle of the present invention, many experiments are carried out, it is specific that some are given below
Case：
Case 1, thank so-and-so：Man, 37 years old, on ordinary days because teeth brushing way is incorrect, bacterial plaque was serious, used within continuous 1 month
The oral cavity anti-inflammatory gargle of the present invention, daily 6-8 times, bacterial plaque substantially mitigates at present.
Case 2, Lv：Man, 41 years old, on ordinary days because teeth brushing way is incorrect, love was had tea, and had obvious tartar in teeth space, even
Continuous 1 first quarter moon is using the oral cavity shield tooth gargle of the present invention, and daily 3-4 times, tartar significantly reduces at present.
Case 3, Wang：Female, 60 years old, bleeding gums were serious when brushing teeth on ordinary days, and continuous two weeks uses oral cavity of the invention
Anti-inflammatory gargle, daily 3-4 times, bleeding gums problem is effectively alleviated at present.
Case 4, marquis so-and-so：Man, 44 years old, smoke and drink on ordinary days, be known as halitosis, the continuous 2 months oral cavities using the present invention
Anti-inflammatory gargle, daily 3-4 times, halitosis disappears substantially at present.
Case 5, Lin：Female, 28 years old, because operating pressure is big and often stays up late and causes swelling and aching of gum, use in continuous 5 days
The oral cavity anti-inflammatory gargle of the present invention, daily 3-4 times, swelling and aching of gum problem is effectively alleviated at present.
Claims (8)
1. a kind of oral cavity anti-inflammatory gargle, it is characterised in that by percentage to the quality, composed of the following components：
2. anti-inflammatory gargle in oral cavity according to claim 1, it is characterised in that by percentage to the quality, by following components
Composition：
3. anti-inflammatory gargle in oral cavity according to claim 1, it is characterised in that by percentage to the quality, by following components
Composition：
4. anti-inflammatory gargle in oral cavity according to claim 1, it is characterised in that by percentage to the quality, by following components
Composition：
5. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that described natural plant
Thing essential oil is lemon.
6. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that live on described surface
Property agent is poloxamer188.
7. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that described edible color
Element is lemon yellow.
8. the oral cavity anti-inflammatory gargle according to any one in Claims 1 to 4, it is characterised in that the water for go from
Sub- water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710833358.6A CN107412111A (en) | 2017-09-15 | 2017-09-15 | A kind of oral cavity anti-inflammatory gargle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710833358.6A CN107412111A (en) | 2017-09-15 | 2017-09-15 | A kind of oral cavity anti-inflammatory gargle |
Publications (1)
| Publication Number | Publication Date |
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| CN107412111A true CN107412111A (en) | 2017-12-01 |
Family
ID=60432912
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710833358.6A Pending CN107412111A (en) | 2017-09-15 | 2017-09-15 | A kind of oral cavity anti-inflammatory gargle |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109431901A (en) * | 2018-12-13 | 2019-03-08 | 中原工学院 | A kind of effectively antibacterial salting liquid of gargling |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125690A (en) * | 2015-09-23 | 2015-12-09 | 北京水木中天植物科学研究院 | Oral anti-inflammation spray |
| CN105125425A (en) * | 2015-09-23 | 2015-12-09 | 北京水木中天植物科学研究院 | Oral anti-inflammation collutory |
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2017
- 2017-09-15 CN CN201710833358.6A patent/CN107412111A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105125690A (en) * | 2015-09-23 | 2015-12-09 | 北京水木中天植物科学研究院 | Oral anti-inflammation spray |
| CN105125425A (en) * | 2015-09-23 | 2015-12-09 | 北京水木中天植物科学研究院 | Oral anti-inflammation collutory |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109431901A (en) * | 2018-12-13 | 2019-03-08 | 中原工学院 | A kind of effectively antibacterial salting liquid of gargling |
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Application publication date: 20171201 |