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CN1080289A - 3-(1H-四唑-5-基)-4H-吡啶并[1，2-a]嘧啶-4-酮，含有该化合物的药物组合物及其制备 - Google Patents

3-(1H-四唑-5-基)-4H-吡啶并[1，2-a]嘧啶-4-酮，含有该化合物的药物组合物及其制备 Download PDF

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Publication number
CN1080289A
CN1080289A CN93102959.7A CN93102959A CN1080289A CN 1080289 A CN1080289 A CN 1080289A CN 93102959 A CN93102959 A CN 93102959A CN 1080289 A CN1080289 A CN 1080289A
Authority
CN
China
Prior art keywords
compound
alkyl
tetrazolium
logical formula
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93102959.7A
Other languages
English (en)
Chinese (zh)
Inventor
I·赫梅茨
J·辛泊斯
L·瓦萨里·尼·德布雷塞
Z·卡普
A·霍瓦施
M·巴洛格
G·克雷姿特里
K·博尔
A·帕乔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of CN1080289A publication Critical patent/CN1080289A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN93102959.7A 1992-02-13 1993-02-13 3-(1H-四唑-5-基)-4H-吡啶并[1，2-a]嘧啶-4-酮，含有该化合物的药物组合物及其制备 Pending CN1080289A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9200432A HUT64064A (en) 1992-02-13 1992-02-13 Process for producing puyrido/1,2-a/pyrimidine derivatives and pharmaceutical compositions comprising same as active ingredient
HU432/92 1992-02-13

Publications (1)

Publication Number Publication Date
CN1080289A true CN1080289A (zh) 1994-01-05

Family

ID=10981335

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93102959.7A Pending CN1080289A (zh) 1992-02-13 1993-02-13 3-(1H-四唑-5-基)-4H-吡啶并[1，2-a]嘧啶-4-酮，含有该化合物的药物组合物及其制备

Country Status (7)

Country Link
CN (1) CN1080289A (fr)
AU (1) AU3573793A (fr)
HU (1) HUT64064A (fr)
IL (1) IL104706A0 (fr)
MX (1) MX9300779A (fr)
SI (1) SI9300075A (fr)
WO (1) WO1993016076A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU209793B (en) * 1990-09-25 1994-11-28 Chinoin Gyogyszer Es Vegyeszet Process for the production of pyrido[1,2-a]pyrimidine-derivatives and pharmaceutical compositions containing the same
ITMI20011764A1 (it) * 2001-08-10 2003-02-10 Dinamite Dipharma Spa Metodo per l'ottenimento del pemirolast ad elevata purezza
US7692011B2 (en) * 2002-10-04 2010-04-06 Prana Biotechnology Limited 8-hydroxy and 8-mercapto quinazolinones
WO2007093184A2 (fr) * 2006-02-13 2007-08-23 Astion Pharma A/S Traitement de l'acne et autres maladies
EP1818058A3 (fr) * 2006-02-13 2007-11-07 Astion Pharma A/S Traitement de l'acné et autres maladies
WO2011008487A1 (fr) 2009-06-29 2011-01-20 Incyte Corporation Pyrimidinones comme inhibiteurs de pi3k
WO2011075643A1 (fr) 2009-12-18 2011-06-23 Incyte Corporation Dérivés condensés d'hétéroaryles substitués à titre d'inhibiteurs de pi3k
US9193721B2 (en) 2010-04-14 2015-11-24 Incyte Holdings Corporation Fused derivatives as PI3Kδ inhibitors
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
EP2655374B1 (fr) 2010-12-20 2019-10-23 Incyte Holdings Corporation N-(1-(phényl substitué)éthyl)-9h-purin-6-amines en tant qu'inhibiteurs de pi3k
WO2012125629A1 (fr) 2011-03-14 2012-09-20 Incyte Corporation Dérivés diamino-pyrimidines et diamino-pyridines substituées en tant qu'inhibiteurs de pi3k
WO2012135009A1 (fr) 2011-03-25 2012-10-04 Incyte Corporation Dérivés de pyrimidine-4,6-diamine en tant qu'inhibiteurs de pi3k
KR102371532B1 (ko) 2011-09-02 2022-03-07 인사이트 홀딩스 코포레이션 Ｐｉ３ｋ 억제제로서 헤테로시클릴아민
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
WO2015191677A1 (fr) 2014-06-11 2015-12-17 Incyte Corporation Dérivés d'hétéroarylaminoalkylphényle bicycliques à titre d'inhibiteurs de pi3k
PL3262046T3 (pl) 2015-02-27 2021-05-04 Incyte Corporation Sole inhibitora pi3k i sposoby ich wytwarzania
WO2016183060A1 (fr) 2015-05-11 2016-11-17 Incyte Corporation Procédé de synthèse d'un inhibiteur de phospho-inositide 3-kinases
WO2016183063A1 (fr) 2015-05-11 2016-11-17 Incyte Corporation Formes cristallines d'un inhibiteur de pi3k
KR20210018328A (ko) 2018-06-01 2021-02-17 인사이트 코포레이션 Pi3k 관련 장애의 치료를 위한 투여 요법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2044796C (fr) * 1990-06-21 2001-10-16 Atsunori Sano Procede de production d'un derive de pyrido [1,2-a] pyrimidine

Also Published As

Publication number Publication date
HU9200432D0 (en) 1992-04-28
HUT64064A (en) 1993-11-29
SI9300075A (en) 1993-09-30
AU3573793A (en) 1993-09-03
WO1993016076A1 (fr) 1993-08-19
IL104706A0 (en) 1993-06-10
MX9300779A (es) 1993-09-30

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WD01 Invention patent application deemed withdrawn after publication