CN109276278B - Small animal subcutaneous tumor drawing holder - Google Patents

Abstract

The invention discloses a small animal subcutaneous tumor extraction holder, which comprises a syringe barrel, a piston body, a piston rod, a rear seat and a needle, wherein the needle is fixedly arranged at the front end of the syringe barrel, the piston body is matched and sleeved in the syringe barrel, the piston rod is fixed at the rear end of the piston body, the rear seat is positioned at the rear end of the piston rod, the axial center positions of the piston body and the piston rod are of an integrated hollow structure, the rear end of the central hole is sealed by the rear seat, a core rod is sleeved in a needle tube and the central hole, the core rod comprises a small diameter section and a large diameter section, the small diameter section is matched and sleeved in the needle tube, and a stop part for limiting excessive rear movement of the core rod is arranged in the middle section of the piston rod, which is matched and sleeved in the central hole. According to the invention, the core rod can be driven by the piston to move forwards and backwards, but no matter the core rod is in the front pole position or the rear pole position, the core rod is always positioned in the needle tube, so that the subcutaneous tumor sample of the small animal is always reserved at the inner side of the needle tube, and the subcutaneous tumor sample cannot enter the cylinder of the injector, and a small amount of sampling and effectiveness are ensured.

Description

Small animal subcutaneous mass extraction gripper

technical field

The invention belongs to the technical field of sampling tools for animal husbandry and veterinary and medical animal model experiments, and in particular relates to a sampling gripper suitable for accurate and rapid extraction of subcutaneous tumors of small animals.

Background technique

When subcutaneously sampling small animals such as cats and pet dogs, and small experimental animals such as guinea pigs, rats, mice, tree shrews, etc., it is often necessary to extract samples from subcutaneous masses for pathological analysis and disease prevention and control. The way to suck, there is no better tool to use. When using a syringe to aspirate, the operation is very difficult, and it is often difficult for a single person to complete. First of all, the operator needs to control the location of the small animal tumor with one hand for accurate needle injection, and the other hand needs to complete the suction process of the syringe. When controlling the suction of the syringe with one hand, it is difficult to accurately control its suction intensity. Due to the very small sample volume of the subcutaneous mass of small animals, it can only be kept in the needle tube when sucking with a syringe. If the sample is sucked into the barrel of the syringe, the sample cannot be taken out, resulting in sampling failure. Moreover, when sampling through a syringe, even if it is completed with the cooperation of multiple people, it is difficult to achieve accurate sampling results, and the sampling time is long, the operation is difficult, and it is difficult to secure the animal. Animals are in a state of stress for a long time, which is easy to cause damage to animals.

Contents of the invention

Aiming at the current difficulty in controlling a small amount of small animal sampling process, it is difficult for a single person to effectively complete the sampling process, and the sampling process is easy to cause sampling loss. and sampling efficiency.

The solution adopted by the present invention to solve the technical problem is: a small animal subcutaneous mass extraction gripper, comprising a syringe barrel, a piston body, a piston rod, a back seat and a needle tube, wherein the needle tube is fixedly installed on the front end of the syringe barrel, and the piston The body is matched with the syringe barrel, the piston rod is fixed at the rear end of the piston body, and the rear seat is located at the rear end of the piston rod. The end is sealed by the backseat, and a core rod is set in the needle tube and the center hole. The core rod includes a thin diameter section and a thick diameter section. The length of the diameter section is not greater than the length of the needle tube, and a stopper for restricting excessive backward movement of the core rod is arranged in the middle section of the piston rod.

Further, a manual push-pull driving mechanism is arranged between the syringe barrel and the rear seat. The manual push-pull driving mechanism is an inherent ring set on the outer front end of the syringe barrel. Fixed shrapnel seats are symmetrically arranged on both sides of the ring sleeve, and movable shrapnel seats are symmetrically arranged on both sides of the back seat. Arched shrapnel protruding outwards are installed between the shrapnel seats.

Wherein, the outer sheath of the thin diameter section of the core rod is inherently a thin diameter sheath, and the outer side of the thick diameter section is provided with a ventilation groove.

The stopper can be realized in multiple ways. The first stopper is to have a side hole in the middle of the piston rod and a fixed stopper along the radial direction. The stopper goes deep into the inner side of the center hole to limit the rear end of the core rod. The stop part mode two is that the inner thread of the central hole of the piston rod is connected with an inner sleeve rod, and the outer end of the inner sleeve rod is positioned at the outside of the center exhaust hole of the rear seat.

Beneficial effects of the present invention: the core rod in the present invention can be driven by the piston to move back and forth, but no matter the core rod is in the front pole position or the rear pole position, the core rod is always located in the needle tube, thereby ensuring that the small animal subcutaneous tumor sample is always kept in the needle tube Inside, it does not enter the syringe barrel, ensuring small and efficient sampling.

When using the present invention, there is no need to consider the problem that the piston rod exceeds the moving range. The experimenter only needs to operate the piston rod to the position where it will no longer move, so the operation is very simple, without considering the degree of precise movement, and the accuracy of sampling and operating efficiency are improved. The process becomes simplified.

When the present invention is driven by means of the arched elastic piece, it only needs to press the arched elastic piece and release the arched elastic piece. When sampling, hold the arched shrapnel firmly with your hand to deform it, without considering the degree of deformation of the shrapnel, and realize fast one-step sampling. When setting out, you only need to loosen the arched shrapnel to discharge a small amount of samples in the needle tube to the corresponding observation position, which further simplifies The operation steps are clear, and the operation process can be completed with one hand.

Description of drawings

Fig. 1 is a schematic view of the appearance of the present invention.

FIG. 2 is a schematic diagram of the internal structure of FIG. 1 .

Fig. 3 is a schematic diagram of the compressed state of Fig. 2 .

Fig. 4 is a structural schematic diagram of the core rod in Fig. 2 .

Fig. 5 is a schematic diagram of the comparison of extreme motion states at both ends of the core rod.

Fig. 6 is a schematic structural view of the inner rod stopper.

Detailed ways

Embodiment 1: The small animal subcutaneous tumor extraction gripper shown in Figure 1 mainly includes syringe barrel 1, piston body 2, piston rod 3, back seat 4, needle tube 5, arched shrapnel 7, core rod 6 and other components . The front end of the syringe barrel 1 is provided with a plug joint or a threaded joint, and the rear side of the needle tube is provided with a needle seat 13 , and the needle seat 13 is sealed and installed with the plug joint or threaded joint of the syringe barrel 1 . A piston body 2 is matched and installed in the syringe barrel 1, a piston rod 3 is fixed at the rear end of the piston body 2, and a rear seat 4 is fixed at the rear end of the piston rod 3, and the rear seat 4 is located outside the syringe barrel 1. The rear end of the syringe barrel 1 is provided with a positioning sleeve 15, and the piston rod 3 passes through the through hole provided in the center of the positioning sleeve 15. The positioning sleeve 15 is provided with an edge exhaust hole 16 to facilitate the exhaust of the piston during movement. and inhale.

Further, a central hole 9 of a hollow structure is provided at the axial center position of the piston body 2 and the piston rod 3, and the central hole 9 runs through the piston rod 3. After the piston rod and the back seat are fixed, the central hole 9 of the piston rod The rear end is sealed by the recoil. Since the axis of the needle tube 5 coincides with the axis of the central hole 9 , the lumen of the needle tube 5 corresponds to the position of the central hole 9 .

Referring to FIG. 2 , the core rod 6 shown in FIG. 4 is set inside the needle tube 5 and the central hole 9 . The core rod 6 includes a thin diameter section 61 and a thick diameter section 62 . , The thick-diameter section 62 is matched and set in the central hole 9 . Moreover, the length of the thin-diameter section 61 is not greater than the length of the needle tube 5 . In addition, a side hole is provided in the middle section of the piston rod 3 and a stop pin 10 is embedded in the radial direction. The stop pin 10 goes deep into the inner side of the central hole 9 to limit the rear end of the core rod 6 .

When the piston rod 3 is driven to drive the piston body 2 to move forward and backward, after the piston body 2 is pulled backward, as shown in Figure 5, the space of the closed chamber 17 located at the front end of the piston body 2 becomes larger, and its enlarged volume V1=πr ₁ ² *△b, absorption volume V2=πr ₂ ² *△a after the core rod 6 traverses, and V1=V2, so △a= r ₁ ² / r ₂ ² *△b, where r ₁ is the piston body 2 Radius, r ₂ is the radius of the thin section 61 of the core rod 6 . It can be seen that a relatively small displacement of the piston rod 3 can drive the core rod 6 to have a relatively large displacement. Since the stop pin 10 is set in the middle of the piston rod 3, the core rod 6 is prevented from moving after touching the stop pin 10. When the piston body 2 continues to move backward, the negative pressure in the closed cavity 17 will increase, so that the piston body 2 Difficulty moving further. After the core rod 6 is moved back, the sampling of the subcutaneous mass of the small animal can always be located inside the needle tube 5 . Visible, in the present invention, core rod 6 also serves as the effect of piston, in order to improve the suction and pushing effect of core rod 6 when moving, can adopt the structure as shown in Figure 5, promptly in the narrow diameter of core rod 6 The outer cover of the section 61 has a thin-diameter sleeve 63 , and the outer side of the thick-diameter section 62 is provided with a ventilation groove 14 . Usually, it is necessary to form an annular groove on the outside of the narrow diameter section 61 , apply glue in the annular groove and fit the thin diameter sleeve 63 .

Embodiment 2: Embodiment 1 provides that the movement of the core rod 6 is driven by the movement of the driving piston, and the front pole position and the rear pole position of the core rod 6 are used as a quantitative and quick way to take samples to ensure that the small animal subcutaneous tumor sample is always kept in the needle tube 5, will not enter the syringe barrel 1, and the operation process becomes very simple, no need to consider the precise movement of the piston rod 3, so as to achieve the purpose of improving the accuracy of sampling and operating efficiency. In this embodiment, in order to further improve the convenience of operation, a manual push-pull driving mechanism is arranged between the syringe barrel 1 and the rear seat 4 .

As shown in Figure 2 and Figure 3, the manual push-pull drive mechanism is a built-in ring sleeve on the outer front end of the syringe barrel 1, fixed shrapnel seats 11 are symmetrically arranged on both sides of the ring sleeve, and movable spring seats 11 are symmetrically arranged on both sides of the rear seat 4. Shrapnel seat 12. Between the corresponding fixed spring seat 11 and the movable spring seat 12, an outwardly protruding arched spring 7 is installed, and a rubber pad 8 is set on the outside thereof for easy handling. During operation, it is only necessary to press the arched shrapnel 7 and release the arched shrapnel 7 to get final product. When sampling, hold the arched shrapnel 7 tightly with your hand to deform it, without considering the degree of deformation of the shrapnel, and realize fast one-step sampling. When setting out, you only need to loosen the arched shrapnel 7 to discharge a small amount of samples in the needle tube 5 to the corresponding observation position , through the improvement of this embodiment, one-handed operation can be realized to complete the sampling and stakeout process.

Embodiment 3: On the basis of the above Embodiment 1 and Embodiment 2, in order to change the sampling volume to adapt to sampling of different small animals or different tissues, a longer needle tube 5 and corresponding core rod 6 can be replaced. By setting a movable stopper, one way is to connect an inner sleeve rod 18 (with a threaded section 19 ) inside the piston rod 3 as shown in FIG. 6 . The position of the inner sleeve rod 18 located in the piston rod 3 is used to control the position of the rear end stop of the core rod 6 . Therefore, it is possible to change the length of the needle tube 5 and the core rod 6, that is, it is possible to change the sampling volume.

Embodiment 4: On the basis of the above embodiment 3, in order to change the sampling volume to adapt to sampling of different small animals or different tissues, the thicker needle tube 5 and the corresponding core rod 6 can be replaced. Also adopt the movable stop member as shown in Figure 6 equally.

Claims (3)

1. The utility model provides a small animal subcutaneous tumor extraction holder, includes syringe barrel, piston body, piston rod and backseat and needle tubing, and wherein needle tubing fixed mounting is in the front end of syringe barrel, and the piston body matches the suit in the syringe barrel, and the piston rod is fixed at the piston body rear end, backseat rear end characterized by: the piston body and the piston rod are of a hollow structure with an integral axial center, the rear end of the central hole is sealed by a rear seat, a core rod is sleeved in the needle tube and the central hole, the core rod comprises a small-diameter section and a large-diameter section, the small-diameter section is matched and sleeved in the needle tube, the large-diameter section is matched and sleeved in the central hole, the length of the small-diameter section is not greater than that of the needle tube, a small-diameter sleeve is sleeved outside the small-diameter section of the core rod, and an air vent groove is formed outside the large-diameter section; a stop component for limiting excessive backward movement of the core rod is arranged at the middle section of the piston rod; a manual push-pull driving mechanism is arranged between the syringe barrel and the rear seat, the manual push-pull driving mechanism is a fixed annular sleeve sleeved at the front end of the outer side of the syringe barrel, fixed spring plate seats are symmetrically arranged on two sides of the annular sleeve, movable spring plate seats are symmetrically arranged on two sides of the rear seat, and an outwards-protruding arched spring plate is arranged between the corresponding fixed spring plate seat and the corresponding movable spring plate seat.

2. The small animal subcutaneous tumor extraction holder of claim 1, wherein: the stop component is provided with a side hole at the middle section of the piston rod and is sleeved with a stop pin which is arranged in the radial direction, and the stop pin penetrates into the inner side of the central hole and is used for limiting the rear end of the core rod.

3. The small animal subcutaneous tumor extraction holder of claim 1, wherein: the stop part is formed by connecting an inner sleeve rod with the inner thread of a central hole of the piston rod, and the outer end of the inner sleeve rod is positioned outside a central exhaust hole of the rear seat.