CN109953921A - A kind of capable of clearing heat and reducing internal heat toothpaste and preparation method thereof - Google Patents
A kind of capable of clearing heat and reducing internal heat toothpaste and preparation method thereof Download PDFInfo
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- CN109953921A CN109953921A CN201910228502.2A CN201910228502A CN109953921A CN 109953921 A CN109953921 A CN 109953921A CN 201910228502 A CN201910228502 A CN 201910228502A CN 109953921 A CN109953921 A CN 109953921A
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- toothpaste
- reducing internal
- heat
- internal heat
- clearing heat
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- 229940034610 toothpaste Drugs 0.000 title claims abstract description 72
- 239000000606 toothpaste Substances 0.000 title claims abstract description 72
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 239000000284 extract Substances 0.000 claims abstract description 20
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 22
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 20
- 239000003086 colorant Substances 0.000 claims description 15
- 235000003599 food sweetener Nutrition 0.000 claims description 15
- 239000003765 sweetening agent Substances 0.000 claims description 15
- 239000000080 wetting agent Substances 0.000 claims description 15
- 239000000654 additive Substances 0.000 claims description 14
- 230000000996 additive effect Effects 0.000 claims description 14
- 239000003002 pH adjusting agent Substances 0.000 claims description 14
- 239000004094 surface-active agent Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 11
- 239000006210 lotion Substances 0.000 claims description 11
- 239000011775 sodium fluoride Substances 0.000 claims description 11
- 235000013024 sodium fluoride Nutrition 0.000 claims description 11
- 239000000377 silicon dioxide Substances 0.000 claims description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 6
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 6
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 4
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 4
- 235000009508 confectionery Nutrition 0.000 claims description 4
- 229920001223 polyethylene glycol Polymers 0.000 claims description 4
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 235000019830 sodium polyphosphate Nutrition 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims description 2
- SGHZXLIDFTYFHQ-UHFFFAOYSA-L Brilliant Blue Chemical compound [Na+].[Na+].C=1C=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C(=CC=CC=2)S([O-])(=O)=O)C=CC=1N(CC)CC1=CC=CC(S([O-])(=O)=O)=C1 SGHZXLIDFTYFHQ-UHFFFAOYSA-L 0.000 claims description 2
- XCJYREBRNVKWGJ-UHFFFAOYSA-N copper(II) phthalocyanine Chemical compound [Cu+2].C12=CC=CC=C2C(N=C2[N-]C(C3=CC=CC=C32)=N2)=NC1=NC([C]1C=CC=CC1=1)=NC=1N=C1[C]3C=CC=CC3=C2[N-]1 XCJYREBRNVKWGJ-UHFFFAOYSA-N 0.000 claims description 2
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 2
- 235000019477 peppermint oil Nutrition 0.000 claims description 2
- 239000000049 pigment Substances 0.000 claims description 2
- 229940085605 saccharin sodium Drugs 0.000 claims description 2
- 239000004408 titanium dioxide Substances 0.000 claims description 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims 2
- 239000000571 coke Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 239000002304 perfume Substances 0.000 claims 1
- 229910000160 potassium phosphate Inorganic materials 0.000 claims 1
- 235000011009 potassium phosphates Nutrition 0.000 claims 1
- 230000000740 bleeding effect Effects 0.000 abstract description 7
- 208000024891 symptom Diseases 0.000 abstract description 6
- 208000020670 canker sore Diseases 0.000 abstract description 5
- 230000008961 swelling Effects 0.000 abstract description 5
- 206010006326 Breath odour Diseases 0.000 abstract description 4
- 208000032139 Halitosis Diseases 0.000 abstract description 4
- 241001570521 Lonicera periclymenum Species 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 208000032843 Hemorrhage Diseases 0.000 description 6
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 241000180649 Panax notoginseng Species 0.000 description 3
- 235000003143 Panax notoginseng Nutrition 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 2
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 2
- 229940074393 chlorogenic acid Drugs 0.000 description 2
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 2
- 235000001368 chlorogenic acid Nutrition 0.000 description 2
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- LRDGATPGVJTWLJ-UHFFFAOYSA-N luteolin Natural products OC1=CC(O)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 LRDGATPGVJTWLJ-UHFFFAOYSA-N 0.000 description 2
- 235000009498 luteolin Nutrition 0.000 description 2
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- -1 purificant Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- RYCLIXPGLDDLTM-UHFFFAOYSA-J tetrapotassium;phosphonato phosphate Chemical compound [K+].[K+].[K+].[K+].[O-]P([O-])(=O)OP([O-])([O-])=O RYCLIXPGLDDLTM-UHFFFAOYSA-J 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 241000790917 Dioxys <bee> Species 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 244000167230 Lonicera japonica Species 0.000 description 1
- 235000017617 Lonicera japonica Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- NEEQFPMRODQIKX-REOHCLBHSA-N N(3)-oxalyl-L-2,3-diaminopropionic acid Chemical compound OC(=O)[C@@H](N)CNC(=O)C(O)=O NEEQFPMRODQIKX-REOHCLBHSA-N 0.000 description 1
- 241000208343 Panax Species 0.000 description 1
- ILRCGYURZSFMEG-UHFFFAOYSA-N Salidroside Natural products OC1C(O)C(O)C(CO)OC1OCCC1=CC=C(O)C=C1 ILRCGYURZSFMEG-UHFFFAOYSA-N 0.000 description 1
- 229910003978 SiClx Inorganic materials 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229920003064 carboxyethyl cellulose Polymers 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000000039 congener Substances 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 210000004268 dentin Anatomy 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000013016 learning Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- ILRCGYURZSFMEG-RQICVUQASA-N salidroside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1OCCC1=CC=C(O)C=C1 ILRCGYURZSFMEG-RQICVUQASA-N 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 235000017709 saponins Nutrition 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The embodiment of the invention discloses a kind of capable of clearing heat and reducing internal heat toothpaste, the toothpaste includes Honegsukle flower P.E and Notogineng Extract.By making containing corresponding functional component in toothpaste, to play the role of capable of clearing heat and reducing internal heat, reaches and treat and prevent resulting throat and swelling and aching of gum, bleeding gums, canker sore, the purpose of the symptoms such as dry halitosis.The other side of the embodiment of the present invention additionally provides the preparation method of the capable of clearing heat and reducing internal heat toothpaste.
Description
Technical field
The present invention relates to personal-care supplies technical fields, and in particular to a kind of capable of clearing heat and reducing internal heat toothpaste and preparation method thereof.
Background technique
Toothpaste is the substance for being used for teeth surfaces together with toothbrush.It can protect oral hygiene, and safe to the human body.
The main ingredient of ordinary toothpaste includes abrasive, adhesive, purificant, wetting agent, preservative, aromatic and water, is had general
The shared effect of toothpaste.
According to the definition of toothpaste, toothpaste should comply with the following terms requirement:
(1) film and bacterial plaque that can remove dental surface are without damaging enamel and dentine;
(2) there is good cleaning oral cavity and surrounding effect;
(3) non-toxic, it is non-stimulated to oral mucosa;
(4) there are comfortable fragrance and taste, there is cool and sweet-smelling feeling after use;
(5) easy to use, at uniform, bright, soft bar when extrusion;
(6) it is easy to clean from oral cavity and on tooth, toothbrush.
(7) there is good chemically and physically stability, guarantee that indices are met the requirements of the standard in the storage phase;
(8) there is reasonable cost performance.
Current toothpaste usually adds certain implication functional component on the basis of ordinary toothpaste, passes through toothpaste when brushing teeth
It reaches in dental surface or tooth ambient enviroment, the functional component of the carrying in toothpaste is made to play corresponding effect, such as pre- preventing decayed tooth
Tooth, fresh breath etc..
With the acceleration of people's life rhythm, the pressure increase of working and learning, diet and irregular, many people's warps of resting
It often gets angry, to suffer from throat and swelling and aching of gum, bleeding gums, canker sore, the symptoms such as dry halitosis greatly affected people
Life.Toothpaste is the product that can directly contact site of pathological change and use daily, it is therefore desirable to propose a kind of tooth of new component
Cream, can solve the above problem.
Summary of the invention
The embodiment of the present invention is designed to provide a kind of capable of clearing heat and reducing internal heat toothpaste, contains corresponding function in toothpaste by making
Ingredient reaches to play the role of capable of clearing heat and reducing internal heat and treats and prevents resulting above-mentioned symptom purpose.The embodiment of the present invention
The preparation method of the capable of clearing heat and reducing internal heat toothpaste is additionally provided on the other hand.
To achieve the above object, the embodiment of the present invention provides a kind of capable of clearing heat and reducing internal heat toothpaste, and the toothpaste includes that honeysuckle mentions
Take object and Notogineng Extract.
Honeysuckle, just entitled honeysuckle (scientific name: Lonicera japonica Thunb.), medicinal material honeysuckle is born for Caprifoliaceae
Platymiscium honeysuckle in winter and congener dry flower or with the flower just opened.Honeysuckle is known as clearing heat and detoxicating good medicine from ancient times.It
Property sweet cold air fragrance, clear heat with drugs of sweet flavour and cold nature is without injuring one's stomach, and fragrance is thoroughly up to again can eliminating evil.Honeysuckle can dispelling wind-heat, also kind removing summer-heat blood
Poison is used for various febrile diseases, such as body heat, dermexanthesis, macular eruption, heat toxin sore carbuncle, abscess of throat disease, equal significant effect.Honeysuckle mentions
It takes object to extract from honeysuckle flower, is chlorogenic acid containing effective component in addition to the effect of above-mentioned medicinal material honeysuckle
(Chlorogenic Acid) and luteolin (Luteolin) has the function of antibacterial and enhancing immune function, and can inhibit
The synthesis of drug-fast bacteria protein.
Radix Notoginseng is the dry root and rhizome of panax araliaceae plant (Panax notoginseng (Burk.) F.H.Chen).
Sweet in flavor, slight bitter, it is warm-natured, return liver, stomach, the heart, small intestinl channel.With dissipating stasis and stanching bleeding, detumescence ding-tong, Xu-tonic and other effects.Cure mainly use
In hemoptysis, spit blood, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling etc..Notogineng Extract extracts from slender acanthopanax
The root of section plant Radix Notoginseng, containing plurality of active ingredients such as saponins, dencichine, flavones, volatile oil, amino acid, carbohydrates, total soap
Salidroside content is about 12%, is the main active in Notogineng Extract.
The toothpaste of the embodiment of the present invention by toothpaste component simultaneously add Honegsukle flower P.E and Notogineng Extract into
Row compounding, so that on the basis of capable of clearing heat and reducing internal heat, while throat and swelling and aching of gum are eliminated, and bleeding gums, canker sore, dry mouth
The symptoms such as smelly, treating both manifestation and root cause of disease, significant effect.
Further, the toothpaste includes following component by percentage to the quality: D-sorbite 28-32%, silica
18-22%, Honegsukle flower P.E 0.5-1.5%, Notogineng Extract 0.5-1.5%, sodium fluoride 0.1-0.2%, wetting agent 3.0-
4.2%, surfactant 0.2-0.5%, pH adjusting agent 0.1-0.3%, viscosity-control additive 0.4-0.8%, sweetener 0.1-
0.3%, essence 0.05-0.15%, colorant 0.05-0.15%, remaining is pure water.
Further, the toothpaste includes following component by percentage to the quality: D-sorbite 29-31%, silica
19-21%, Honegsukle flower P.E 0.8-1.2%, Notogineng Extract 0.8-1.2%, sodium fluoride 0.15-0.2%, wetting agent 3.5-
4.0%, surfactant 0.3-0.4%, pH adjusting agent 0.15-0.25%, viscosity-control additive 0.6-0.7%, sweetener 0.15-
0.25%, essence 0.08-0.12%, colorant 0.07-0.11%, remaining is pure water.
In one embodiment, the toothpaste includes following component by percentage to the quality: D-sorbite 30%, dioxy
SiClx 20%, Honegsukle flower P.E 1%, Notogineng Extract 1%, sodium fluoride 0.176%, wetting agent 3.67%, surfactant
0.37%, pH adjusting agent 0.21%, viscosity-control additive 0.65%, sweetener 0.2%, essence 0.1%, colorant 0.09%,
Remaining is pure water.
Further, the wetting agent includes glycerol, sodium polyphosphate and/or polyethylene glycol (PEG-12).In a reality
It applies in scheme, based on the toothpaste and by percentage to the quality, the wetting agent includes glycerol 3%, 0.17 and of sodium polyphosphate
Polyethylene glycol 0.5.
Further, the surfactant includes NaLS and/or Cocoamidopropyl betaine.At one
In embodiment, based on the toothpaste and by percentage to the quality, the surfactant includes 0.2% He of NaLS
Cocoamidopropyl betaine 0.17%.
Further, the pH adjusting agent includes potassium pyrophosphate and/or sodium hydroxide.In one embodiment, it is based on
The toothpaste and by percentage to the quality, the pH adjusting agent includes potassium pyrophosphate 0.2% and sodium hydroxide 0.01%.
Further, the viscosity-control additive includes cellulose gum and/or xanthan gum.The cellulose gum is with cellulose
Adhesive made from derivative, for including that solid and liquid are fused together and to form stable cream by the various composition in toothpaste
Body, cellulose gum can be for example carboxymethyl cellulose, carboxyethyl cellulose etc..In one embodiment, it is based on the tooth
Cream and by percentage to the quality, the viscosity-control additive includes cellulose gum 0.5% and xanthan gum 0.15%.
Further, the sweetener can be the common sweetener of toothpaste in the prior art, for increasing to toothpaste
Sweet taste promotes mouthfeel when user uses toothpaste.In one embodiment, based on the toothpaste and by percentage to the quality,
The sweetener includes saccharin sodium, such as 0.2%.
Further, the essence can be for the common essence of toothpaste in the prior art, the day including extracting from animals and plants
Right essence and artificial synthetic essence, for tarting up to toothpaste, to promote mouthfeel when user uses toothpaste and pure and fresh
Implication.In one embodiment, based on the toothpaste and by percentage to the quality, the essence includes peppermint oil, such as
0.1%.
Further, the colorant can be the common colorant of toothpaste in the prior art, for lotion of toothpaste
Assign color or color combination.In one embodiment, based on the toothpaste and by percentage to the quality, the colorant packet
Include titanium dioxide, such as 0.05%, pigment brilliant blue (FCF eats cyan 1 (Japan)), such as 0.02% and phthalocyanine blue (BGS
), such as 0.02% LA-61-02.
The other side of the embodiment of the present invention additionally provides the preparation method of the capable of clearing heat and reducing internal heat toothpaste, the method packet
Include the step of each component is mixed to form lotion of toothpaste.
The embodiment of the present invention has the advantages that
1, it is added to Honegsukle flower P.E and Notogineng Extract in lotion of toothpaste component, on the basis of capable of clearing heat and reducing internal heat, together
When eliminate throat and swelling and aching of gum, bleeding gums, canker sore, the symptoms such as dry halitosis, treating both manifestation and root cause of disease, significant effect.
2, each group distribution ratio is reasonable, and cleaning of teeth effect is good, comfortable taste.
3, the preparation process by adjusting existing lotion of toothpaste is easy to obtain the product of the embodiment of the present invention, convenient for pushing away
Extensively.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book is understood other advantages and efficacy of the present invention easily, it is clear that described embodiment is the present invention one
Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing
Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.
Embodiment 1
Capable of clearing heat and reducing internal heat toothpaste described in the present embodiment includes following component by percentage to the quality: D-sorbite 30%, two
Silica 20%, Honegsukle flower P.E 1%, Notogineng Extract 1%, sodium fluoride 0.176%, wetting agent 3.67%, surface-active
Agent 0.37%, pH adjusting agent 0.21%, viscosity-control additive 0.65%, sweetener 0.2%, essence 0.1%, colorant 0.09%,
Remaining is pure water.
Preparation method includes that above-mentioned each component is mixed to form lotion of toothpaste.
Embodiment 2
Capable of clearing heat and reducing internal heat toothpaste described in the present embodiment includes following component by percentage to the quality: D-sorbite 29%, two
Silica 21%, Honegsukle flower P.E 0.8%, Notogineng Extract 1.2%, sodium fluoride 0.2%, wetting agent 3.5%, surface-active
Agent 0.4%, pH adjusting agent 0.25%, viscosity-control additive 0.6%, sweetener 0.15%, essence 0.1%, colorant 0.08%,
Remaining is pure water.
Preparation method includes that above-mentioned each component is mixed to form lotion of toothpaste.
Embodiment 3
Capable of clearing heat and reducing internal heat toothpaste described in the present embodiment includes following component by percentage to the quality: D-sorbite 31%, two
Silica 19%, Honegsukle flower P.E 1.2%, Notogineng Extract 0.8%, sodium fluoride 0.2%, wetting agent 4.0%, surface-active
Agent 0.4%, pH adjusting agent 0.2%, viscosity-control additive 0.7%, sweetener 0.15%, essence 0.1%, colorant 0.1%, remaining
For pure water.
Preparation method includes that above-mentioned each component is mixed to form lotion of toothpaste.
Embodiment 4
Capable of clearing heat and reducing internal heat toothpaste described in the present embodiment includes following component by percentage to the quality: D-sorbite 28%, two
Silica 18%, Honegsukle flower P.E 1.5%, Notogineng Extract 1.5%, sodium fluoride 0.2%, wetting agent 4.2%, surface-active
Agent 0.5%, pH adjusting agent 0.3%, viscosity-control additive 0.8%, sweetener 0.2%, essence 0.1%, colorant 0.1%, remaining
For pure water.
Preparation method includes that above-mentioned each component is mixed to form lotion of toothpaste.
Embodiment 5
Capable of clearing heat and reducing internal heat toothpaste described in the present embodiment includes following component by percentage to the quality: D-sorbite 32%, two
Silica 22%, Honegsukle flower P.E 0.5%, Notogineng Extract 0.5%, sodium fluoride 0.1%, wetting agent 3.0%, surface-active
Agent 0.2%, pH adjusting agent 0.1%, viscosity-control additive 0.4%, sweetener 0.2%, essence 0.1%, colorant 0.1%, remaining
For pure water.
Preparation method includes that above-mentioned each component is mixed to form lotion of toothpaste.
The above-mentioned toothpaste each group distribution ratio that the embodiment of the present invention obtains is reasonable, and cleaning of teeth effect is good, comfortable taste.Lotion
Honegsukle flower P.E and Notogineng Extract are added in component, on the basis of capable of clearing heat and reducing internal heat, while it is swollen to eliminate throat and gum
Bitterly, bleeding gums, canker sore, the symptoms such as dry halitosis, treating both manifestation and root cause of disease, significant effect.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (10)
1. a kind of capable of clearing heat and reducing internal heat toothpaste, which is characterized in that the toothpaste includes Honegsukle flower P.E and Notogineng Extract.
2. capable of clearing heat and reducing internal heat toothpaste according to claim 1, which is characterized in that under the toothpaste includes by percentage to the quality
Column component: D-sorbite 28-32%, silica 1 8-22%, Honegsukle flower P.E 0.5-1.5%, Notogineng Extract 0.5-
1.5%, sodium fluoride 0.1-0.2%, wetting agent 3.0-4.2%, surfactant 0.2-0.5%, pH adjusting agent 0.1-0.3%,
Viscosity-control additive 0.4-0.8%, sweetener 0.1-0.3%, essence 0.05-0.15%, colorant 0.05-0.15%, remaining is
Pure water.
3. capable of clearing heat and reducing internal heat toothpaste according to claim 1, which is characterized in that under the toothpaste includes by percentage to the quality
Column component: D-sorbite 29-31%, silica 1 9-21%, Honegsukle flower P.E 0.8-1.2%, Notogineng Extract 0.8-
1.2%, sodium fluoride 0.15-0.2%, wetting agent 3.5-4.0%, surfactant 0.3-0.4%, pH adjusting agent 0.15-
0.25%, viscosity-control additive 0.6-0.7%, sweetener 0.15-0.25%, essence 0.08-0.12%, colorant 0.07-
0.11%, remaining is pure water.
4. capable of clearing heat and reducing internal heat toothpaste according to claim 1, which is characterized in that under the toothpaste includes by percentage to the quality
Column component: D-sorbite 30%, silica 20%, Honegsukle flower P.E 1%, Notogineng Extract 1%, sodium fluoride 0.176%,
Wetting agent 3.67%, surfactant 0.37%, pH adjusting agent 0.21%, viscosity-control additive 0.65%, sweetener 0.2%, perfume
Smart 0.1%, colorant 0.09%, remaining is pure water.
5. the capable of clearing heat and reducing internal heat toothpaste according to any one of claim 2-4, which is characterized in that the wetting agent includes sweet
Oil, sodium polyphosphate and/or polyethylene glycol.
6. the capable of clearing heat and reducing internal heat toothpaste according to any one of claim 2-4, which is characterized in that the surfactant includes
NaLS and/or Cocoamidopropyl betaine.
7. the capable of clearing heat and reducing internal heat toothpaste according to any one of claim 2-4, which is characterized in that the pH adjusting agent includes coke
Potassium phosphate and/or sodium hydroxide.
8. the capable of clearing heat and reducing internal heat toothpaste according to any one of claim 2-4, which is characterized in that the viscosity-control additive includes
Cellulose gum and/or xanthan gum.
9. the capable of clearing heat and reducing internal heat toothpaste according to any one of claim 2-4, which is characterized in that the sweetener includes saccharin
Sodium;The essence includes peppermint oil;The colorant includes titanium dioxide, pigment brilliant blue and phthalocyanine blue.
10. the preparation method of the capable of clearing heat and reducing internal heat toothpaste according to any one of claim 2-9, which is characterized in that the side
Method includes the steps that each component being mixed to form lotion of toothpaste.
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Cited By (1)
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| CN111110602A (en) * | 2020-01-19 | 2020-05-08 | 广东立爽生物科技有限公司 | Anti-inflammatory analgesic toothpaste and preparation method thereof |
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