CN101912301B - Surgical treatment instrument for treating human liver tumor by using high-voltage nanosecond pulse - Google Patents

Abstract

The invention discloses an operation therapeutic instrument for treating human liver tumor by using high-voltage nanosecond pulse, which comprises a pulse generator, a puncture type needle array electrode and a pressurizing hemostasis device, wherein the pulse generator is connected with the puncture type needle array electrode; the puncture-type needle array electrode comprises a needle puncture-type test contact, a coaxial high-voltage cable inner conductor, a coaxial high-voltage cable outer conductor, an insulating dielectric layer, a probe outer ring, a metal fixing ring, a coaxial high-voltage cable outer insulating layer and a needle fixing screw. The device does not need radiation or chemical medicine injection, has small volume, light weight, portability and easy high-pressure disinfection, can be used for volume reduction treatment before liver tumor operation in an operating room, and can also be used for auxiliary treatment of tumor recurrence after liver tumor resection.

Description

A Surgical Therapeutic Apparatus for Treating Human Liver Tumors Using High Voltage Nanosecond Pulses

technical field

The invention relates to the technical field of bioelectronic treatment of tumors, in particular to a surgical treatment instrument for treating human liver tumors with high-voltage nanosecond pulses.

Background technique

The existing treatment of liver tumors is mainly surgical treatment. The existing surgical wounds are large, and there is a lot of blood loss during the operation, and the operation time is long, which affects the patient as a whole. At the same time, radiation or chemical drug injections will cause great damage to human body functions. Existing therapeutic instruments are bulky and inconvenient to go out for medical treatment.

Contents of the invention

The purpose of the present invention is to overcome the deficiencies in the prior art. The device of the present invention is small in size, light in weight, portable and easy to autoclave for surgical treatment of human liver tumors.

A surgical treatment instrument for treating human liver tumors with high-voltage nanosecond pulses of the present invention includes a pulse generator, a puncture-type needle-like array electrode and a pressurized hemostatic device; the puncture-type needle-like array electrode includes a needle-like puncture Type test contact, inner conductor of coaxial high voltage cable, outer conductor of coaxial high voltage cable, insulating dielectric layer, outer ring of probe, metal fixing ring, outer insulating layer of coaxial high voltage cable and needle fixing screw; the needle puncture type The test contact includes a central test contact and four outer ring test contacts, the four outer ring test contacts have through holes for spraying gelatin sponge and saline; the central test contact is fixed on the coaxial high-voltage cable On the inner conductor, the outer ring test contact is fixed on the outer conductor of the coaxial high-voltage cable; there is an insulating dielectric layer between the inner conductor of the coaxial high-voltage cable and the outer conductor of the coaxial high-voltage cable; the needle-like puncture test There is an outer ring of the probe between the contacts; the outer conductor of the coaxial high-voltage cable is fixed by a metal fixing ring and the outer insulating layer of the coaxial high-voltage cable; contact; the pulse generator communicates with the inner conductor of the coaxial high voltage cable and the outer conductor of the coaxial high voltage cable.

The pulse generator is 100 ns.

The needle-shaped puncture test contact is cobalt-molybdenum alloy.

The inner conductor of the coaxial high voltage cable and the outer conductor of the coaxial high voltage cable are made of copper material.

The outer ring of the probe is made of stainless steel.

The metal fixing ring is made of stainless steel,

The outer insulating layer of the coaxial high-voltage cable is made of insulating rubber.

The present invention has the following advantages:

The invention belongs to a surgical treatment instrument for treating human liver tumors by using high-voltage nanosecond pulses, and belongs to the technical field of bioelectronic treatment of tumors. The device can generate a pulsed electric field with a rising speed of 30 nanoseconds, a pulse width of 100 nanoseconds, and a repetition rate of 10 Hz. Under the guidance of ultrasound, it can be percutaneously punctured through a special puncture needle array electrode with pressurized hemostasis function. Orthotopic treatment of liver tumors. No radiation or chemical drug injection is required. The device of the present invention is small in size, light in weight, portable, and easy to be sterilized by high pressure. It can be used for volume reduction treatment of liver tumors in operating rooms, and can also be used for adjuvant treatment of tumor recurrence after liver tumor resection.

Description of drawings

Fig. 1 is a longitudinal sectional structural diagram of an embodiment of the present invention.

FIG. 2 is a cross-sectional structural diagram of FIG. 1 .

Detailed ways

The present invention is further described below by embodiment:

Figure 1 and Figure 2, a surgical treatment instrument for treating human liver tumors with high-voltage nanosecond pulses, which includes a pulse generator (purchased from California Bioelectronic Medical Equipment Company), a puncture-type needle array electrode and a pressurized hemostasis device The puncture-type needle-like array electrode and pressurized hemostatic device include needle-like puncture-type test contact 1, coaxial high-voltage cable inner conductor 2, coaxial high-voltage cable outer conductor 3, insulating dielectric layer 4, probe outer ring 5, metal fixing Ring 6, coaxial high-voltage cable outer insulating layer 7 and needle fixing screw 8; needle-shaped puncture test contact 1 includes a central test contact and four outer ring test contacts, and the four outer ring test contacts have through holes Used to spray gelatin sponge and normal saline; the center test contact is fixed on the inner conductor 2 of the coaxial high-voltage cable, and the outer ring test contact is fixed on the outer conductor 3 of the coaxial high-voltage cable; the inner conductor 2 of the coaxial high-voltage cable and the coaxial There is an insulating dielectric layer 4 between the outer conductors 3 of the high-voltage cable; there is a probe outer ring 5 between the needle-like puncture test contacts 1; there is a metal fixing ring 6 and an outer insulating layer of the coaxial high-voltage cable outside the outer conductor 3 of the coaxial high-voltage cable 7 is fixed; the needle head fixing screw 8 is passed through the outer ring 5 of the probe to fix the outer ring test contact; the pulse generator is connected to the inner conductor 2 of the coaxial high-voltage cable and the outer conductor 3 of the coaxial high-voltage cable.

Among them, the pulse generator is 100 nanoseconds. The needle-piercing test contacts are cobalt-molybdenum alloy. The inner conductor of the coaxial high voltage cable and the outer conductor of the coaxial high voltage cable are made of copper material. The outer ring of the probe is made of stainless steel. The metal fixing ring is made of stainless steel, and the outer insulating layer of the coaxial high-voltage cable is made of insulating rubber.

During use, the lower end of the surgical treatment instrument of the present invention is connected to the output end of the high-voltage pulse generator through a high-voltage cable joint (BNC). The inner conductor 2 of the coaxial high-voltage cable is injected into the center needle of the needle array. Due to the insulation and high-voltage resistance characteristics of the insulating dielectric layer 4, the current will pass through the tumor tissue to reach the four needle-shaped puncture-type test contacts 1 on the periphery, and then flow into the same needle through the outer ring 5 of the probe. The outer conductor 3 of the shaft high-voltage cable returns to the high-voltage pulse grounding end to complete the loop.

The needle fixing screw 8 fixes the four needle-like puncture-type test contacts 1 on the periphery through the holes drilled on the side of the probe outer ring 5, and the length of the needle-like puncture-type test contacts 1 can be adjusted as required. The metal fixing ring 6 clamps the outer ring 5 of the probe and the outer conductor 3 of the coaxial high-voltage cable through the tool pliers to play a fixing role.

After the pulse transmission is completed, the needle-like puncture test contact 1 can flush the tumor treatment wound with sterile frozen saline through the pipeline in the outer conductor 3 of the coaxial high-voltage cable, and press it to stop bleeding, and then spray gelatin sponge to block the puncture needle hole after the end of treatment.

In the present invention, five test contacts form a centered four-surround arrangement to ensure that the center of the tumor is covered by the center test contact, the electric field distribution reaches a peak value, and the periphery of the tumor is covered by four ring-shaped test contacts. To, the electric field decreases gradually, without harming the normal liver around the tumor.

Finally, it should also be noted that the above examples are only specific implementation examples of the present invention. Apparently, the present invention is not limited to the above examples, and many variations are possible. All deformations that can be directly derived or associated by those skilled in the art from the content disclosed in the present invention should be considered as the protection scope of the present invention.

Claims (7)

1. surgery instrument that utilizes high-voltage nanosecond pulse treatment human liver tumor, it is characterized in that: it comprises pulse generator, puncture type needle-like array electrode and Pressur hemostatic device; Described puncture type needle-like array electrode comprises needle-like puncture type test contact, coaxial high tension cable inner wire, coaxial high tension cable outer conductor, insulation dielectric layer, probe outer shroud, metal retainer ring, coaxial high tension cable external insulation layer and syringe needle fixed screw; Described needle-like puncture type test contact comprises a center examination contact and four outer shroud examination contacts, and described four outer shrouds examination contact has through hole to be used to spray gelfoam and normal saline; Center examination contact is fixed on the coaxial high tension cable inner wire, and outer shroud examination contact is fixed on the coaxial high tension cable outer conductor; Between described coaxial high tension cable inner wire and the coaxial high tension cable outer conductor insulation dielectric layer is arranged; Between the described needle-like puncture type test contact probe outer shroud is arranged; Described coaxial high tension cable outer conductor has metal retainer ring and coaxial high tension cable external insulation layer to fix outward; Described syringe needle fixed screw side is through on the probe outer shroud fixedly, and outer shroud tries contact; Described pulse generator is communicated with coaxial high tension cable inner wire and coaxial high tension cable outer conductor.

2. surgery instrument according to claim 1 is characterized in that: described pulse generator was 100 nanoseconds.

3. surgery instrument according to claim 1 is characterized in that: described needle-like puncture type test contact is a cobalt molybdenum alloy.

4. surgery instrument according to claim 1 is characterized in that: described coaxial high tension cable inner wire and coaxial high tension cable outer conductor adopt copper product.

5. surgery instrument according to claim 1 is characterized in that: described probe outer shroud adopts stainless steel material.

6. surgery instrument according to claim 1 is characterized in that: described metal retainer ring adopts rustless steel.

7. surgery instrument according to claim 1 is characterized in that: described coaxial high tension cable external insulation layer adopts electro-insulating rubber.

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