CN102100547B - Optical coherence tomography detection device and operating method thereof - Google Patents
Optical coherence tomography detection device and operating method thereof Download PDFInfo
- Publication number
- CN102100547B CN102100547B CN 200910261350 CN200910261350A CN102100547B CN 102100547 B CN102100547 B CN 102100547B CN 200910261350 CN200910261350 CN 200910261350 CN 200910261350 A CN200910261350 A CN 200910261350A CN 102100547 B CN102100547 B CN 102100547B
- Authority
- CN
- China
- Prior art keywords
- path difference
- optical
- optical path
- light
- reflected light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 16
- 238000012014 optical coherence tomography Methods 0.000 title claims abstract 14
- 238000011017 operating method Methods 0.000 title 1
- 230000003287 optical effect Effects 0.000 claims abstract description 341
- 230000005540 biological transmission Effects 0.000 claims abstract description 15
- 230000008878 coupling Effects 0.000 claims abstract description 8
- 238000010168 coupling process Methods 0.000 claims abstract description 8
- 238000005859 coupling reaction Methods 0.000 claims abstract description 8
- 230000001427 coherent effect Effects 0.000 claims abstract 6
- 239000004973 liquid crystal related substance Substances 0.000 claims description 50
- 239000000463 material Substances 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 23
- 230000000694 effects Effects 0.000 claims description 16
- 230000008859 change Effects 0.000 claims description 8
- 238000006243 chemical reaction Methods 0.000 claims description 8
- 238000012545 processing Methods 0.000 claims description 6
- 238000009736 wetting Methods 0.000 claims 4
- 239000003086 colorant Substances 0.000 claims 2
- 238000005286 illumination Methods 0.000 description 81
- 238000003325 tomography Methods 0.000 description 49
- 210000002858 crystal cell Anatomy 0.000 description 42
- 238000010276 construction Methods 0.000 description 25
- 230000005611 electricity Effects 0.000 description 25
- 238000007639 printing Methods 0.000 description 19
- 238000002310 reflectometry Methods 0.000 description 17
- 238000013459 approach Methods 0.000 description 15
- 238000010586 diagram Methods 0.000 description 5
- 238000013519 translation Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000026062 Tissue disease Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000002601 radiography Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Images
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Liquid Crystal (AREA)
Abstract
The invention provides an optical coherence tomography detection device, which comprises a light source, an optical coupling module and an optical path difference generation module. The light source is used for emitting coherent light. The optical coupling module is used for dividing the coherent light into a first incident light and a second incident light. The first incident light is emitted to an object to be detected to generate a first reflected light; the second incident light is emitted to the optical path difference generating module, and the optical path difference generating module generates second reflected light according to the second incident light in a mode of changing the light transmission/reflection property of at least one optical element of the optical path difference generating module, so that the second reflected light and the first reflected light have optical path difference.
Description
Technical field
The present invention relates to optical detection, especially relate to a kind of optics people having the same aspiration and interest tomography checkout gear and operational approach thereof that need not to utilize mechanical framework that the effect that optical path difference and optical frequency change can be provided.
Background technology
In recent years; Along with optical detective technology is constantly progressive; Structure and composition that the optical image scanning technique provides the method for a non-intrusion type to understand the determinand tissue; Because its characteristic quick and non-intrusion type makes the technology of this type have quite widely and uses, particularly be applied on the medical diagnosis.When light incides in the organizational structure; Variation along with the different depth medium; The absorption characteristic of light and scattering properties also can change thereupon, and optical image scanning is exactly to utilize various different optical methods to reach to such an extent that obtain high resolution image thus at organization internal and the entrained information of scattered photon.
Generally speaking; The medical science shadowgraph technique puts on the change in physical properties that is produced after the biological tissue through measuring the physics field source; Convert visual pattern into; Help the textural anomaly state and dynamic functional assessment of the analysis biological tissue of clinical medicine qualitative, quantitative, quick and correct state of an illness Clinics and Practices is provided, greatest help is arranged for the lifting of quality of medical care.In the development trend of medical science shadowgraph technique, hope to measure radiography with the non-intruding mode towards using non-freeization energy field source, can have high spatial resolution and contrast resolution, and direction such as real-time visualization ability develops.
In known various medical science shadowgraph techniques, a kind of medical science shadowgraph technique that is called optics people having the same aspiration and interest tomoscan art (OCT) is called optical section again; Add that with its low same tone light source change optical path difference interferometer measures framework; In order to the people having the same aspiration and interest characteristic of measurement biological tissue backscattering distribution of light intensity, and then the composition diagram picture, two dimension even three-dimensional image can be obtained; The geneogenous growth requirement that meets above-mentioned medical science shadowgraph technique; Cause the attention sight of global many research teams, make its fast development, nowadays the developmental research of existing many applications.
In practical application; Because optics people having the same aspiration and interest tomoscan is simultaneously with advantages such as high-resolution, high sensitivity, non-free performance field source and inexpensive; And can measure cross section structure of determinand interior tissue and velocity profile simultaneously; So the resolution image of micron grade can be provided, very large help be arranged, the for example amphiblestroid detection of eyeball for the diagnosis and the cyto-architectural location that help tissue disease.
Please with reference to Fig. 1, Fig. 1 shows the sketch map of traditional optical people having the same aspiration and interest tomography checkout gear.As shown in Figure 1; The same light modulation that this optics people having the same aspiration and interest tomography checkout gear utilizes McKesson interferometer (Michelson interferometer) that people having the same aspiration and interest light source is sent is divided into two roads via beam splitter; One light directive reference edge also reflected by reference edge; Another road light is directive determinand end and reflected by the determinand end then; This twice reflected light arrives optical sensor through beam splitter once more, and computer installation utilizes the optical path difference that both produced to obtain the optical data about the vertical cross section of determinand again.In fact, this optical sensor can be spectrogrph, optical frames group or other any optical sensor with light sensing function, does not have certain restriction.
In addition, please with reference to Fig. 2, Fig. 2 shows the basic framework sketch map of the optics people having the same aspiration and interest tomography checkout gear among above-mentioned Fig. 1.In order to produce the optical path difference between reference edge and the determinand end; This optics people having the same aspiration and interest tomography checkout gear need be provided with some quite complicated optical elements; For example optical-mechanical system, pivoting mechanism and frequency conversion light source etc., and need to rely on the mechanical framework of a translation or rotation to reach the effect that produces optical path difference.Also can know by Fig. 2; Traditional optical people having the same aspiration and interest tomography checkout gear 1 is that to obtain different optical path through the position that changes reflecting mirror 14 (being parallel to moving or being rotated of z direction among Fig. 2) poor, tries to achieve the sensing result of determinand 16 on depth direction (being the z direction among Fig. 2) through the McKesson optical interference effect thus.
No matter be the optics people having the same aspiration and interest tomography checkout gear among Fig. 1 or Fig. 2; All need rely on the mechanical framework of a translation or rotation to reach the effect that produces optical path difference; Not only can increase the cost of optics people having the same aspiration and interest tomography checkout gear; Also make the framework of optics people having the same aspiration and interest tomography checkout gear become comparatively complicated, and its volume also possibly become comparatively huge.Therefore, the present invention proposes a kind of optics people having the same aspiration and interest tomography checkout gear and operational approach thereof, to address the above problem.
Summary of the invention
First specific embodiment according to the present invention is a kind of optics people having the same aspiration and interest tomography checkout gear.In this embodiment, this optics people having the same aspiration and interest tomography checkout gear comprises light source, optical coupler module and optical path difference generation module.This optical path difference generation module comprises at least one optical element.This light source is in order to send same light modulation.This optical coupler module was in order to being divided into first incident illumination and second incident illumination with light modulation.This first incident illumination directive, one determinand and produce first reflected light; This this optical path difference generation module of second incident illumination directive; The mode of the printing opacity/reflectivity properties of this optical path difference generation module through changing this at least one optical element produces second reflected light according to this second incident illumination, causes between this second reflected light and this first reflected light to have optical path difference.
In practical application; This at least one optical element can be the liquid crystal cells of multilamellar arrangement, the electrochromics material that multilamellar is arranged, electricity wet construction unit, leaded light (lightguide) unit or the optical switch element etc. that multilamellar is arranged; This optical path difference generation module utilizes the switching of the printing opacity/reflectivity properties of this at least one optical element, does not reach to see through the effect that mechanical framework can produce optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear of the present invention; This at least one optical element is a plurality of liquid crystal cells that multilamellar is arranged; The anglec of rotation of this optical path difference generation module through adjusting those liquid crystal cells to be to change the printing opacity/reflectivity properties of those liquid crystal cells, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear of the present invention; This at least one optical element is the electrochromics material that multilamellar is arranged; When this second incident illumination is incident upon the electrochromics material of this multilamellar arrangement; The electrochromics material that this optical path difference generation module is arranged through this multilamellar demonstrates different printing opacity/reflectivity properties corresponding to the different color light of this second incident illumination, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
Preferably, the relation of said optical path difference generation module coloured light capable of using and wavelength provides the effect of light frequency conversion.
In according to optics people having the same aspiration and interest tomography checkout gear of the present invention; This at least one optical element is the wet construction unit of multiwalled electricity; The wet construction unit of this multiwalled electricity that this optical path difference generation module is passed through through this second incident illumination has the different transmission medium, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear of the present invention; This at least one optical element is a plurality of light elements; This optical path difference generation module is through switching the direction of those light elements, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear of the present invention; This at least one optical element is a plurality of optical switch elements; This optical path difference generation module through switching those optical switch elements unlatching or close, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
Preferably, this optical switch element is the bubble type switch.
In according to optics people having the same aspiration and interest tomography checkout gear of the present invention, this optical coupler module is a beam splitter.
According to optics people having the same aspiration and interest tomography checkout gear of the present invention, further comprise: optical sensing module, in order to receive this optical path difference between this first reflected light and this second reflected light and this first reflected light of sensing and this second reflected light; And processing module, be coupled to this optical sensing module, in order to obtain optical data about the vertical cross section of this determinand according to this optical path difference.
Second specific embodiment according to the present invention is a kind of optics people having the same aspiration and interest tomography checkout gear How It Works.In this embodiment, this optics people having the same aspiration and interest tomography checkout gear comprises light source, optical coupler module and optical path difference generation module.This optical path difference generation module comprises at least one optical element.This method comprises the following step: (a) this light source sends same light modulation; (b) this optical coupler module should be divided into first incident illumination and second incident illumination with light modulation; (c) this first incident illumination directive, one determinand and produce first reflected light; (d) this this optical path difference generation module of second incident illumination directive; The mode of the printing opacity/reflectivity properties of this optical path difference generation module through changing this at least one optical element produces second reflected light according to this second incident illumination, causes between this second reflected light and this first reflected light to have optical path difference.
In practical application; This at least one optical element can be the liquid crystal cells of multilamellar arrangement, the electrochromics material that multilamellar is arranged, electricity wet construction unit, light element or the optical switch element that multilamellar is arranged; This method system utilizes the switching of the printing opacity/reflectivity properties of this at least one optical element, and then reaches and need not utilize mechanical framework can produce the effect of optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention; This at least one optical element is a plurality of liquid crystal cells that multilamellar is arranged; The anglec of rotation of this optical path difference generation module through adjusting those liquid crystal cells to be to change the printing opacity/reflectivity properties of those liquid crystal cells, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention; This at least one optical element is the electrochromics material that multilamellar is arranged; When this second incident illumination is incident upon the electrochromics material of this multilamellar arrangement; The electrochromics material that this optical path difference generation module is arranged through this multilamellar demonstrates different printing opacity/reflectivity properties corresponding to the different color light of this second incident illumination, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
Preferably, this optical path difference generation module also can provide the effect of light frequency conversion through the relation of coloured light and wavelength.
In according to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention; This at least one optical element is the wet construction unit of multiwalled electricity; The wet construction unit of this multiwalled electricity that this optical path difference generation module is passed through through this second incident illumination has the different transmission medium, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention; This at least one optical element is a plurality of light elements; This optical path difference generation module is through switching the direction of those light elements, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
In according to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention; This at least one optical element is a plurality of optical switch elements; This optical path difference generation module through switching those optical switch elements unlatching or close, cause this second reflected light that this optical path difference generation module produced can and this first reflected light between have this optical path difference.
Preferably, those optical switch elements are the bubble type switch.
In according to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention, this optical coupler module is a beam splitter.
According to optics people having the same aspiration and interest tomography checkout gear operational approach of the present invention, further comprise the following step: (e) receive this optical path difference between this first reflected light and this second reflected light and this first reflected light of sensing and this second reflected light; And (f) obtain optical data about the vertical cross section of this determinand according to this optical path difference.
Than prior art; Because the switching through the printing opacity/reflectivity properties of its optical element (for example liquid crystal cells, electrochromics material, electricity wet construction unit, light element and optical switch element etc.) produces optical path difference according to optics people having the same aspiration and interest tomography checkout gear of the present invention and operational approach thereof; Event can effectively be avoided traditional optical people having the same aspiration and interest tomography checkout gear need be provided with quite complicated optical element and need to rely on the mechanical framework of a translation or rotation to reach the shortcoming that produces optical path difference; Make the framework of this optics people having the same aspiration and interest tomography checkout gear significantly to simplify; And its manufacturing cost also can reduce; Even the relation of coloured light also capable of using and wavelength provides the effect of light frequency conversion, so have market potential.
Can further be understood through following detailed Description Of The Invention and accompanying drawing about advantage of the present invention and spirit.
Description of drawings
Fig. 1 shows the sketch map of traditional optical people having the same aspiration and interest tomography checkout gear.
Fig. 2 shows the basic framework sketch map of the optics people having the same aspiration and interest tomography checkout gear among Fig. 1.
Fig. 3 shows the functional block diagram according to the optics people having the same aspiration and interest tomography checkout gear of first specific embodiment of the present invention.
Fig. 4 A shows the sketch map that the optical path difference generation module comprises the liquid crystal cells of a plurality of multilamellars arrangements.Fig. 4 B shows liquid crystal cells and moves the generation optical path difference through being parallel to second incident illumination.Fig. 4 C shows liquid crystal cells produces optical path difference through the mode of rotation sketch map.Fig. 4 D shows liquid crystal cell layer and comprises the sketch map that two rows are parallel to the liquid crystal cells of second incident illumination arrangement.
Fig. 5 A shows the sketch map that the optical path difference generation module comprises the electrochromics material of a plurality of multilamellars arrangements.Fig. 5 B shows the second incident illumination L
I Pass electrochromics material 240 but by the sketch map of electrochromics material 242 reflection.
Fig. 6 A shows the sketch map that the optical path difference generation module comprises the wet construction unit of electricity of a plurality of multilamellars arrangements.Fig. 6 B shows the second incident illumination L
IPass the wet construction unit 240 of electricity but the sketch map of wet construction unit 242 reflections of quilt electricity.
Fig. 7 A shows the sketch map that the optical path difference generation module comprises a plurality of optical switch elements.A plurality of optical switch elements that Fig. 7 B shows the optical path difference generation module produce the sketch map of the second catoptrical another kind of situation.
Fig. 8 shows the flow chart according to the optics people having the same aspiration and interest tomography checkout gear operational approach of second specific embodiment of the present invention.
The specific embodiment
First specific embodiment according to the present invention is a kind of optics people having the same aspiration and interest tomography checkout gear.In this embodiment, this optics people having the same aspiration and interest tomography checkout gear obtains the optical data about the vertical cross section of this determinand thus in order to a determinand is detected.Please with reference to Fig. 3, Fig. 3 shows the functional block diagram of this optics people having the same aspiration and interest tomography checkout gear.
As shown in Figure 3, optics people having the same aspiration and interest tomography checkout gear 2 comprises light source 20, optical coupler module 22, optical path difference generation module 24, determinand module 26, optical sensing module 28 and processing module 30.Wherein, optical coupler module 22 is coupled to optical sensing module 28; Optical sensing module 28 is coupled to processing module 30.In addition, light source 20 is a people having the same aspiration and interest light source; Optical coupler module 22 is beam splitter or any device with beam split function; Determinand module 26 is in order to place this determinand; Optical path difference generation module 24 comprises at least one optical element; And this at least one optical element can be the liquid crystal cells of multilamellar arrangement, the electrochromics material that multilamellar is arranged, electricity wet construction unit, light element or the optical switch element that multilamellar is arranged, and does not have certain restriction.
In this embodiment, light source 20 is in order to send same light modulation.Optical coupler module 22 should be divided into first incident illumination and second incident illumination with light modulation in order to what light source 20 sent, and wherein, this first incident illumination is in order to directive determinand module 26, and this second incident illumination is in order to directive optical path difference generation module 24.When this first incident illumination directive was arranged at this determinand of determinand module 26 and produces, this determinand promptly can be reflected into first reflected light with this first incident illumination.When this second incident illumination directive optical path difference generation module 24; Optical path difference generation module 24 will be through changing this at least one optical element the mode of printing opacity/reflectivity properties produce according to this second incident illumination and be reflected into second reflected light, cause between this second reflected light and this first reflected light to have optical path difference.
It should be noted that; Printing opacity/the reflectivity properties that changes these at least one optical elements when optical path difference generation module 24 is when producing this optical path difference; Because each optical element in this at least one optical element all can record for the printing opacity of this second incident illumination or the size of degree of reflection in advance; That is each optical element is Given information for the printing opacity or the degree of reflection of this second incident illumination, and the set position of each optical element in the optical path difference generation module 24 is also known.
Therefore; No matter how optical path difference generation module 24 changes the printing opacity/reflectivity properties of this at least one optical element; This optical path difference that optical path difference generation module 24 is produced is also all known; And the printing opacity/reflectivity properties of each optical element in this at least one optical element can be recorded in the comparison list with corresponding relation between the different optical path differences, for follow-up usefulness of searching contrast, but not as limit.
Than prior art; The position of each optical element in the optical path difference generation module 24 of the present invention is fixing and is known; Do not need as prior art generally through complicated mechanical system mobile optical element to reach the effect that changes optical path difference; So can simplify the complicated originally framework of this optics people having the same aspiration and interest tomography checkout gear effectively, and can reduce the volume of this optics people having the same aspiration and interest tomography checkout gear.
Because the maximum distinguishing characteristics of the present invention and prior art is optical path difference generation module 24; Therefore; Next, will be elaborated with regard to the different structure of optical path difference generation module 24 and the difference reflection situation of this second incident illumination directive optical path difference generation module 24.Please with reference to Fig. 4 A, Fig. 4 A shows the sketch map that optical path difference generation module 24 comprises the liquid crystal cell layer 240 of multilamellar arrangement.Shown in Fig. 4 A, because the liquid crystal cell layer 240 vertical second incident illumination L
IArrange, therefore, as the second incident illumination L
IWhen injecting optical path difference generation module 24, the most second incident illumination L
IWill be produced the second reflected light L by liquid crystal cell layer 240 reflections
R, the second incident illumination L of few part is only arranged
ICan pass liquid crystal cell layer 240 and produce second and penetrate light L
T
Then, please further with reference to Fig. 4 B, the liquid crystal cell layer 240 that Fig. 4 B shows among Fig. 4 A comprises perpendicular to the second incident illumination L
IThe sketch map of the liquid crystal cells 240a～240c that arranges.Shown in Fig. 4 B, because the liquid crystal cells 240a～240c in the liquid crystal cell layer 240 is all perpendicular to the second incident illumination L
IArrange, so the most second incident illumination L
IWill be produced the second reflected light L by liquid crystal cell layer 240 reflections
R, the second incident illumination L of few part is only arranged
ICan pass liquid crystal cell layer 240 and produce second and penetrate light L
T
On the contrary, please with reference to Fig. 4 C, Fig. 4 C shows liquid crystal cell layer 240 among Fig. 4 A and comprises and be parallel to the second incident illumination L
IThe sketch map of the liquid crystal cells 240a～240c that arranges.Shown in Fig. 4 C, because the liquid crystal cells 240a～240c in the liquid crystal cell layer 240 all is parallel to the second incident illumination L
IArrange, so the most second incident illumination L
ICan pass liquid crystal cell layer 240 and produce second and penetrate light L
T, the second incident illumination L of few part is only arranged
ICan be produced the second reflected light L by liquid crystal cell layer 240 reflections
R
What need explanation is; No matter be the embodiment of above-mentioned Fig. 4 A to C, still all following embodiment are when incident illumination is incident upon multi-form optical path difference generation module; All can some incident illumination can penetrate; The incident illumination of another part then can be reflected, so in all following embodiment, no longer give unnecessary details separately with regard to this point.
In addition, please with reference to Fig. 4 D, Fig. 4 D shows liquid crystal cell layer 240 among Fig. 4 A and comprises two rows and be parallel to the second incident illumination L
IThe sketch map of the liquid crystal cells 240a～240e that arranges.Shown in Fig. 4 D, the liquid crystal cells 240a～240e of liquid crystal cell layer 240 is divided into two rows and is arranged in parallel, and wherein liquid crystal cells 240a～240c is that first row and liquid crystal cells 240d～240e are second row, but not as limit.
Please with reference to Fig. 5 A, Fig. 5 A shows the sketch map that optical path difference generation module 24 comprises the electrochromics material of a plurality of multilamellars arrangements.Shown in Fig. 5 A, when supposing that electrochromics material 240 becomes first color (shown in the figure bend), electrochromics material 240 will reflect the second incident illumination L
I, therefore, as the second incident illumination L
IWhen injecting optical path difference generation module 24, the electrochromics material 240 that presents first color promptly can be with the second incident illumination L
IBe reflected into the second reflected light L
R
Show the second incident illumination L as for Fig. 5 B
I Pass electrochromics material 240 but by the sketch map of electrochromics material 242 reflection.Shown in Fig. 5 B, when supposing that electrochromics material 240 becomes second color (shown in white among the figure), the second incident illumination L
ICan pass electrochromics material 240.Therefore, as the second incident illumination L
IWhen injecting optical path difference generation module 24, the second incident illumination L
IPromptly can pass the electrochromics material 240 that presents second color, but the second incident illumination L
IThe electrochromics material 242 that promptly can be presented first color subsequently is reflected into the second reflected light L
R'.
Comparison diagram 5A and Fig. 5 B can know, because the second reflected light L among Fig. 5 B
R' promptly be different from the second reflected light L among Fig. 5 A
RSo optical path difference generation module 24 can be that first color or second color reach the effect that changes the optical path difference between first reflected light that second reflected light and this determinand reflected through switching its electrochromics material 240 and 242.
Please with reference to Fig. 6 A, Fig. 6 A shows the sketch map that optical path difference generation module 24 comprises the wet construction unit of electricity of a plurality of multilamellars arrangements.Shown in Fig. 6 A, suppose that wet construction unit 240 central authorities of electricity become first and transmit medium when (as scheming shown in the bend), the second incident illumination L will be reflected in wet construction unit 240 central authorities of electricity
I, therefore, as the second incident illumination L
IWhen injecting optical path difference generation module 24, the wet construction unit 240 of electricity with first transmission medium promptly can be with the second incident illumination L
IBe reflected into the second reflected light Lf
R
Show the second incident illumination L as for Fig. 6 B
IPass the wet construction unit 240 of electricity but the sketch map of wet construction unit 242 reflections of quilt electricity.Shown in Fig. 6 B, when supposing that the wet construction unit 240 of electricity becomes the second transmission medium (shown in white among the figure), the second incident illumination L
ICan pass the wet construction unit 240 of electricity.Therefore, as the second incident illumination L
IWhen injecting optical path difference generation module 24, the second incident illumination L
IPromptly can pass the wet construction unit 240 of the electricity with second transmission medium, but the second incident illumination L
IThe wet construction unit 242 of electricity that promptly can be had the first transmission medium subsequently is reflected into the second reflected light L
R'.
Comparison diagram 6A and Fig. 6 B can know, because the second reflected light L among Fig. 6 B
R' promptly be different from the second reflected light L among Fig. 6 A
RSo optical path difference generation module 24 can be first to transmit medium or second and transmit medium and reach the effect that changes the optical path difference between first reflected light that second reflected light and this determinand reflected through switching the wet construction unit 240 and 242 of its electricity.
Please with reference to Fig. 7 A, Fig. 7 A shows the sketch map that optical path difference generation module 24 comprises a plurality of optical switch elements.In practical application, those optical switch elements can be that popple dome (bubble switch) or other have the switch module that changes the refraction angle function, do not have certain restriction.
Shown in Fig. 7 A, optical path difference generation module 24 comprises optical switch element 240,242,244 and 246.As the second incident illumination L
IWhen injecting optical path difference generation module 24, the second incident illumination L
IWill run into optical switch element 240 earlier, because optical switch element 240 is in closed condition, so the second incident illumination L
IPromptly can be refracted to optical switch element 242 by optical switch element 240.At this moment, because optical switch element 242 also is in closed condition, so the second incident illumination L
IPromptly can be refracted to optical switch element 244 by optical switch element 242.In like manner, the second incident illumination L
IWill further be refracted to optical switch element 246 by optical switch element 244, then, the second incident illumination L
IWill be got back to optical switch element 240 by optical switch element 246 refractions.At this moment, because optical switch element 240 is switched to opening, so the second reflected light L
RCan penetrate smoothly outside the optical path difference generation module 24.
Please with reference to Fig. 7 B, a plurality of optical switch elements that Fig. 7 B shows optical path difference generation module 24 produce the sketch map of the second catoptrical another kind of situation.Shown in Fig. 7 B, as the second incident illumination L
IWhen injecting optical path difference generation module 24, because optical switch element 240 is in opening, so the second incident illumination L
ICan pass optical switch element 240 and arrive optical switch element 246.If optical switch element 246 has reflection function, then optical switch element 246 can be with the second incident illumination L
IReflect back into optical switch element 240.If optical switch element 240 still is in opening at this moment, then the second reflected light L
R' can penetrate smoothly outside the optical path difference generation module 24.
Second specific embodiment according to the present invention is a kind of optics people having the same aspiration and interest tomography checkout gear operational approach.In this embodiment, this optics people having the same aspiration and interest tomography checkout gear comprises light source, optical coupler module and optical path difference generation module, and this optical path difference generation module comprises at least one optical element.In fact, this light source can be a people having the same aspiration and interest light source; This optical coupler module can be beam splitter or other any device with beam split function, does not have certain limitation.
Please with reference to Fig. 8, Fig. 8 shows the flow chart of this optics people having the same aspiration and interest tomography checkout gear operational approach.As shown in Figure 8, at first, in step S10, this light source sends same light modulation.Then, in step S12, this optical coupler module should be divided into first incident illumination and second incident illumination with light modulation.Afterwards, in step S14, this first incident illumination directive, one determinand and produce first reflected light.Then; In step S16; This this optical path difference generation module of second incident illumination directive; This optical path difference generation module will be through changing this at least one optical element the mode of printing opacity/reflectivity properties produce second reflected light according to this second incident illumination, cause between this second reflected light and this first reflected light to have optical path difference.
In one embodiment; This at least one optical element can be a plurality of liquid crystal cells that multilamellar is arranged; The anglec of rotation of this optical path difference generation module through adjusting those liquid crystal cells to be to change the printing opacity/reflectivity properties of those liquid crystal cells, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.
In one embodiment; This at least one optical element can be the electrochromics material that multilamellar is arranged; When this second incident illumination is incident upon the electrochromics material of this multilamellar arrangement; The electrochromics material that this optical path difference generation module is arranged through this multilamellar demonstrates different printing opacity/reflectivity properties corresponding to the different color light of this second incident illumination, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.It should be noted that except producing this optical path difference this optical path difference generation module also can provide the effect of light frequency conversion through the relation of coloured light and wavelength.
In one embodiment; This at least one optical element can be the wet construction unit of multiwalled electricity; The wet construction unit of this multiwalled electricity that this optical path difference generation module is passed through through this second incident illumination has the different transmission medium, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.
In one embodiment; This at least one optical element can be a plurality of light elements; This optical path difference generation module is through switching the direction of those light elements, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.
In one embodiment, this at least one optical element can be a plurality of optical switch elements, and for example, those optical switch elements can be the bubble type switches, but not as limit.In fact, this optical path difference generation module through switching those optical switch elements unlatching or close, cause this second reflected light that this optical path difference generation module reflected can and this first reflected light between have this optical path difference.
After producing this optical path difference between this first reflected light and this second reflected light, in step S18, receive also this optical path difference between this first reflected light of sensing and this second reflected light thus of this first reflected light and this second reflected light.At last, in step S20, obtain optical data about the vertical cross section of this determinand according to this optical path difference.
Than prior art; Because the switching through the printing opacity/reflectivity properties of its optical element (for example liquid crystal cells, electrochromics material, electricity wet construction unit, light element and optical switch element etc.) produces optical path difference according to optics people having the same aspiration and interest tomography checkout gear of the present invention and operational approach thereof; Event can effectively be avoided traditional optical people having the same aspiration and interest tomography checkout gear need be provided with quite complicated optical element and need to rely on the mechanical framework of a translation or rotation to reach the shortcoming that produces optical path difference; Make the framework of this optics people having the same aspiration and interest tomography checkout gear significantly to simplify; And its manufacturing cost also can reduce, even also the effect of light frequency conversion can be provided through the relation of coloured light and wavelength.
Through the detailed description of above preferred specific embodiment, hope can be known description characteristic of the present invention and spirit more, and is not to come protection scope of the present invention is limited with the above-mentioned preferred specific embodiment that is disclosed.On the contrary, its objective is that hope can contain the arrangement of various changes and tool equality in the protection domain of the claim of institute of the present invention desire application.
The primary clustering symbol description
S10～S20: process step
1,2: optics people having the same aspiration and interest tomography checkout gear 10,20: light source
12,22: optical coupling unit 14: reflecting mirror
16: determinand 18: data processing unit
24: optical path difference generation module 26: the determinand module
28: optical sensing module 30: processing module
L
I: the second incident illumination L
R, L
R': second reflected light
L
T: second penetrates light 240a～240e: liquid crystal cells
240,242,244,246: optical element.
Claims (20)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200910261350 CN102100547B (en) | 2009-12-22 | 2009-12-22 | Optical coherence tomography detection device and operating method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200910261350 CN102100547B (en) | 2009-12-22 | 2009-12-22 | Optical coherence tomography detection device and operating method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102100547A CN102100547A (en) | 2011-06-22 |
| CN102100547B true CN102100547B (en) | 2012-12-19 |
Family
ID=44153775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200910261350 Expired - Fee Related CN102100547B (en) | 2009-12-22 | 2009-12-22 | Optical coherence tomography detection device and operating method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102100547B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI450706B (en) * | 2011-04-14 | 2014-09-01 | Crystalvue Medical Corp | Intraocular pressure detecting device and detecting method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI279606B (en) * | 2005-09-06 | 2007-04-21 | Univ Nat Cheng Kung | Method and device for automatic focusing of optical fiber type optical coherence tomography |
| CN101049232A (en) * | 2006-04-07 | 2007-10-10 | 周晟 | Optical Tomography Scanning Method and Device |
-
2009
- 2009-12-22 CN CN 200910261350 patent/CN102100547B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI279606B (en) * | 2005-09-06 | 2007-04-21 | Univ Nat Cheng Kung | Method and device for automatic focusing of optical fiber type optical coherence tomography |
| CN101049232A (en) * | 2006-04-07 | 2007-10-10 | 周晟 | Optical Tomography Scanning Method and Device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102100547A (en) | 2011-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8564784B2 (en) | Large area optical diagnosis apparatus and operating method thereof | |
| Laurenzis et al. | Nonline-of-sight laser gated viewing of scattered photons | |
| US8619237B2 (en) | Laser-scanning intersecting plane tomography such as for high speed volumetric optical imaging | |
| Gomit et al. | Free surface measurement by stereo-refraction | |
| US6909094B2 (en) | System and method for terahertz imaging using a single terahertz detector | |
| Bassan et al. | Transmission FT-IR chemical imaging on glass substrates: applications in infrared spectral histopathology | |
| KR102580984B1 (en) | Image processing method, program and recording medium | |
| JP2009510531A5 (en) | ||
| CN101370426A (en) | Systems, devices, and processes for providing speckle reduction using wavefront modulation for optical coherence tomography | |
| Koch Dandolo et al. | Toward a multimodal fusion of layered cultural object images: complementarity of optical coherence tomography and terahertz time-domain imaging in the heritage field | |
| Ellwood et al. | Photoacoustic imaging using acoustic reflectors to enhance planar arrays | |
| Kishida et al. | Development of real-time time gated digital (TGD) OFDR method and its performance verification | |
| JP6207333B2 (en) | Film thickness measuring method and film thickness measuring apparatus | |
| CN103284684B (en) | Optical device and operation method thereof | |
| Jelly et al. | Deep imaging with 1.3 µm dual-axis optical coherence tomography and an enhanced depth of focus | |
| Liu et al. | Optical single-pixel volumetric imaging by three-dimensional light-field illumination | |
| Brenner et al. | Optical coherence tomography images simulated with an analytical solution of Maxwell’s equations for cylinder scattering | |
| CN109459414A (en) | Optical image-measuring device | |
| JP2017524138A (en) | Instantaneous time-domain optical coherence tomography | |
| CN102100547B (en) | Optical coherence tomography detection device and operating method thereof | |
| Verburg et al. | A century of acousto-optics-from early discoveries to modern sensing of sound with light | |
| Neuhaus et al. | Simultaneous en-face imaging of multiple layers with multiple reference optical coherence tomography | |
| US8582111B2 (en) | Optical coherence tomography apparatus and operating method thereof | |
| Satat et al. | Advances in ultrafast optics and imaging applications | |
| Krishnaswamy et al. | Scanning in situ spectroscopy platform for imaging surgical breast tissue specimens |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121219 Termination date: 20181222 |