CN102551784B - Dedicated breast phantom of CT equipment for breast - Google Patents
Dedicated breast phantom of CT equipment for breast Download PDFInfo
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- CN102551784B CN102551784B CN201210057022.2A CN201210057022A CN102551784B CN 102551784 B CN102551784 B CN 102551784B CN 201210057022 A CN201210057022 A CN 201210057022A CN 102551784 B CN102551784 B CN 102551784B
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- 210000000481 breast Anatomy 0.000 title claims abstract description 13
- 210000005075 mammary gland Anatomy 0.000 claims abstract description 97
- 238000005259 measurement Methods 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims description 7
- 238000002591 computed tomography Methods 0.000 claims description 6
- 210000004907 gland Anatomy 0.000 claims description 6
- 230000003139 buffering effect Effects 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 238000012544 monitoring process Methods 0.000 claims description 4
- 231100000673 dose–response relationship Toxicity 0.000 claims description 3
- 239000012530 fluid Substances 0.000 claims description 3
- 230000005855 radiation Effects 0.000 abstract description 12
- 238000003745 diagnosis Methods 0.000 abstract description 8
- 238000005516 engineering process Methods 0.000 abstract description 5
- 239000000839 emulsion Substances 0.000 abstract 2
- 238000004020 luminiscence type Methods 0.000 abstract 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 229910052750 molybdenum Inorganic materials 0.000 description 7
- 239000011733 molybdenum Substances 0.000 description 7
- 238000003384 imaging method Methods 0.000 description 6
- 208000030270 breast disease Diseases 0.000 description 5
- 206010006187 Breast cancer Diseases 0.000 description 3
- 208000026310 Breast neoplasm Diseases 0.000 description 3
- 231100000987 absorbed dose Toxicity 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000877 morphologic effect Effects 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 210000003484 anatomy Anatomy 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000009607 mammography Methods 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229910052703 rhodium Inorganic materials 0.000 description 1
- 239000010948 rhodium Substances 0.000 description 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 description 1
- 238000012502 risk assessment Methods 0.000 description 1
- 208000011571 secondary malignant neoplasm Diseases 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 238000000904 thermoluminescence Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/58—Testing, adjusting or calibrating thereof
- A61B6/582—Calibration
- A61B6/583—Calibration using calibration phantoms
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- Optics & Photonics (AREA)
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- High Energy & Nuclear Physics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
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- Animal Behavior & Ethology (AREA)
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Abstract
本发明公开了一种针对乳腺专用CT设备的乳腺模体。包括椭圆乳体、若干个探测器放置孔、热释光探测器、固定栓1和固定栓2，其中所述椭圆乳体由椭圆中心平面一分为二，分为两个椭圆半球，所述若干个探测器放置孔均嵌入其中一个椭圆半球内，另一个椭圆半球用于辅助所述乳腺模体构成乳腺的形状；所述探测器放置孔的形状设置为圆孔或小圆柱，所述热释光探测器放置在所述探测器放置孔中进行数据测量；所述固定栓1的四角为圆形角，使空气从四角缝隙中溢出，用于在两个椭圆半球合并时起到固定和缓冲的作用。该专用的乳腺模体可以用来测量和标定乳腺受到的辐射剂量以及剂量的分布，更加有利于控制和评估乳腺所受到的辐射剂量水平，提高乳腺诊断技术。
The invention discloses a mammary gland phantom for mammary gland special CT equipment. It includes an ellipsoidal emulsion, several detector placement holes, a thermoluminescent detector, a fixed plug 1 and a fixed plug 2, wherein the ellipsoidal emulsion is divided into two elliptical hemispheres by the central plane of the ellipse, and the Several detector placement holes are embedded in one of the elliptical hemispheres, and the other elliptical hemisphere is used to assist the mammary gland phantom to form the shape of the mammary gland; the shape of the detector placement holes is set as a round hole or a small cylinder, and the thermal The luminescence detector is placed in the detector placement hole for data measurement; the four corners of the fixing bolt 1 are rounded corners, so that the air overflows from the gaps of the four corners, and is used for fixing and fixing when the two elliptical hemispheres merge. The role of the buffer. The special breast phantom can be used to measure and calibrate the radiation dose received by the breast and the distribution of the dose, which is more conducive to controlling and evaluating the radiation dose level received by the breast and improving breast diagnosis technology.
Description
Technical field
The present invention relates to tomography X CT technical field, relate in particular to a kind of mammary gland die body for the special CT equipment of mammary gland.
Background technology
At present, the sickness rate of breast carcinoma has been in the first place of women's malignant tumor.In existing multiple breast examination method, X ray molybdenum target imaging (Mammography) is the most widely used means.But molybdenum target imaging technique is two-dimentional DR picture, on imaging direction, organizational information superposes mutually, and three-dimensional accurate positioning is poor, for dense form mammary gland, easily occurs false positive mistaken diagnosis, therefore also use clinically whole body CT to carry out breast examination.But whole body CT equipment can only carry out transverse axis bit scan and can not scan separately mammary gland human body, make other when injected organism tissue except mammary gland be subject to unnecessary X-radiation and picture quality is also poor.Therefore, the special CT of mammary gland became a kind of more superior early-stage breast cancer diagnostic method that is considered to of fast development in the last few years.But along with the increasingly extensive use of X ray in diagnosis of breast disease, during breast examination, suffered amount of radiation size also more and more receives people's concern.
In molybdenum target imaging, low energy X ray is directly incident on compressed newborn body after by molybdenum or rhodium filter disc, the peak of its absorbed dose enters a side of mammary gland at X ray, while passing mammary gland along with X-ray, decay gradually, lower in the absorbed dose of mammary gland opposite side.Therefore, in the imaging of X ray molybdenum target, the dose distribution of mammary gland is very inhomogeneous, and the body of gland dosage of local area exceedes medical treatment guidance level.Therefore, a large amount of research that has the secondary cancer radiation risk assessment causing about the imaging of X ray molybdenum target has also caused the more close concern of people in recent years.When using whole body CT examination, its mammary gland is still difficult in the raw, and as patient lies on the back, mammary gland is in its flat presentation, and the distortion that can be squeezed of the prostrate mammary gland of patient.Once mammary gland is in undernatured state, it will lose normal anatomical structures relation, is unfavorable for early diagnosis and the location of disease, and check result is had to larger impact.
In prior art scheme, commercial mammary gland die body is all die bodys that compressed rear one-tenth flat shape is applicable to breast molybdenum target, this die body is not suitable for simulation under the special CT equipment of mammary gland, the situation that mammary gland naturally droops, therefore dosage and the dose distribution that mammary gland is subject to measured and demarcated to the mammary gland die body that lacks mammary gland CT device-specific in prior art, is unfavorable for the carrying out of breast disease diagnosis.
Summary of the invention
The object of this invention is to provide a kind of mammary gland die body for the special CT equipment of mammary gland, this special mammary gland die body can be used for measuring and demarcating the radiation dose that is subject to of mammary gland and the distribution of dosage, more be conducive to control and the suffered radiation dose level of assessment mammary gland, improve breast disease diagnosis technology.
The object of the invention is to be achieved through the following technical solutions:
For a mammary gland die body for the special CT equipment of mammary gland, described mammary gland die body comprises oval newborn body, several detector putting holes, thermoluminescent detector (TLD), gim peg 1 and gim peg 2, wherein:
The newborn body of described ellipse is divided into two by elliptical center plane, is divided into two oval hemisphere, and described several detector putting holes all embed in one of them oval hemisphere, and another oval hemisphere forms the shape of mammary gland for auxiliary described mammary gland die body;
The shape of described detector putting hole is set to circular hole or small column, and described thermoluminescent detector (TLD) is placed in described detector putting hole and carries out DATA REASONING;
Four jiaos of described gim peg 1 is round angle, and air is overflowed from four angle seam gaps, for play effect fixing and buffering when two oval hemisphere merge;
Described gim peg 2, for two oval hemisphere are closely fixing, prevents that described mammary gland die body from coming off in CT scan.
Described several detector putting holes further come interval according to the central plane of the newborn body of described ellipse to surperficial distance and arrange, and by the monitoring of the thermoluminescent detector (TLD) in these detector putting holes, obtain the situation that is uniformly distributed of mammary gland dosage and dosage.
Described thermoluminescent detector (TLD) is further demarcated through the stator of monolithic, is specially: repeatability, stability, energy and dose response to every a slice thermoluminescent detector (TLD) are measured.
In described mammary gland die body, also comprise:
Dosiology is measured film, is placed on the central plane of the newborn body of described ellipse, for obtaining the dose distribution on this central plane;
CT ionization chamber, is arranged on the central axis of the newborn body of described ellipse, for obtaining the dosage on this central shaft, and for the measurement of dose calibration and CT dose index.
In described mammary gland die body, also comprise:
Mammary gland simulated slot, for simulating the structure of breast duct or other mammary gland morphological characteristic, and can input medicinal fluid as required.
The newborn body of described ellipse is selected close to the material of true mammary gland tissue and is made.
The newborn body of described ellipse is comprised of the mixed materials of 50% body of gland and 50% fat.
As seen from the above technical solution provided by the invention, described mammary gland die body comprises oval newborn body, several detector putting holes, thermoluminescent detector (TLD), gim peg 1 and gim peg 2, the newborn body of wherein said ellipse is divided into two by elliptical center plane, be divided into two oval hemisphere, described several detector putting holes all embed in one of them oval hemisphere, and another oval hemisphere forms the shape of mammary gland for auxiliary described mammary gland die body; The shape of described detector putting hole is set to circular hole or small column, and described thermoluminescent detector (TLD) is placed in described detector putting hole and carries out DATA REASONING; Four jiaos of described gim peg 1 is round angle, and air is overflowed from four angle seam gaps, for play effect fixing and buffering when two oval hemisphere merge; Described gim peg 2, for two oval hemisphere are closely fixing, prevents that described mammary gland die body from coming off in CT scan.This special mammary gland die body can be used for measuring and demarcating the radiation dose that is subject to of mammary gland and the distribution of dosage, is more conducive to control and the suffered radiation dose level of assessment mammary gland, improves breast disease diagnosis technology.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme of the embodiment of the present invention, below the accompanying drawing of required use during embodiment is described is briefly described, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, do not paying under the prerequisite of creative work, can also obtain other accompanying drawings according to these accompanying drawings.
The mammary gland die body semiglobe schematic diagram of the special CT equipment of mammary gland that Fig. 1 provides for the embodiment of the present invention;
The profile of the oval hemisphere that Fig. 2 provides for the embodiment of the present invention in specific implementation process.
The specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Based on embodiments of the invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to protection scope of the present invention.
The mammary gland die body of the special CT equipment of mammary gland provided by the present invention be shaped as ellipse, the newborn body naturally drooping when emulation is prostrate, the size dimension of die body can select to be applicable to Asians's mammary gland, die body can be the mixed materials composition of body of gland, fat or body of gland fat; Die body can be opened from elliptical center plane, in a semiellipse, embed through the calibrated thermoluminescent detector (TLD) of monolithic stator therein, by the set positions to the thermoluminescent detector (TLD) embedding, dosage and the dose distribution that after CT scan, just can obtain each position feature point in mammary gland die body, realize object of the present invention.Below in conjunction with accompanying drawing, the embodiment of the present invention is described in further detail, be illustrated in figure 1 the mammary gland die body semiglobe schematic diagram of the special CT equipment of mammary gland that the embodiment of the present invention provides, mammary gland die body in Fig. 1 comprise oval newborn body 1., several detector putting holes 2. (as shown in the digital 1-12 mark in figure), gim peg 1 3., gim peg 2 4., wherein:
1. oval newborn body is divided into two by elliptical center plane, be divided into two oval hemisphere, 2. several detector putting holes all embed in one of them oval hemisphere, another oval hemisphere forms the shape of mammary gland for auxiliary described mammary gland die body, thereby makes the X-ray can be by the distribution situation that is organized in energy deposition on central plane and obtains dosage of different-thickness.
Several detector putting holes shape 2. can be set to circular hole or small column, as shown in Figure 1, the left side of Fig. 1 is the oval hemisphere that is set to small column, the right of Fig. 1 is the oval hemisphere of being arranged to circular hole, thermoluminescent detector (TLD) is placed in this detector putting hole and carries out DATA REASONING, by the set positions to the thermoluminescent detector (TLD) embedding, after CT scan, just can obtain radiation dose and the dose distribution of each position feature point in mammary gland die body like this.
3. four jiaos of gim peg 1 are round angle, air can overflow from four angle seam gaps, reduce the operation easier while fixing, when in Fig. 1, A, two hemisphere of B merge, 3. gim peg 1 can play effect fixing and buffering, because thermoluminescence sheet is very little, not wield feature need to be exerted oneself evenly when merging simultaneously.
4. gim peg 2 in Fig. 1 for by A, final tight the fixing of two hemisphere of B, prevents that mammary gland die body from coming off in CT scan.
In addition, in specific implementation process, above-mentioned several detector putting holes can also further come interval according to the central plane of the newborn body of described ellipse to surperficial distance and arrange, and obtain mammary gland by the situation that is uniformly distributed of the dosage of radiation and dosage by the monitoring of the thermoluminescent detector (TLD) in these detector putting holes.For instance, be illustrated in figure 2 the profile of the oval hemisphere that the embodiment of the present invention provides in specific implementation process, Fig. 2 is the profile of being arranged to the oval hemisphere of small column, with Fig. 1 and Fig. 2 in conjunction with:
Point centered by detector putting hole 1 in Fig. 1, in the horizontal direction, to the distance interval 1cm of detector putting hole 2, to the distance interval 2cm of detector putting hole 3, to the distance interval 3cm of detector putting hole 4, to the distance interval 4cm of detector putting hole 5, to the distance interval 5cm of detector putting hole 6, can obtain like this dose distribution to 5.5cm apart from surperficial 0.5cm in the horizontal direction.Detector putting hole 12 and detector putting hole 3, detector putting hole 13 and detector putting hole 5, detector putting hole 4 and detector putting hole 11, detector putting hole 2 and detector putting hole 10 mapping on horizontal level respectively, can measure the nearly surface of mammary gland dose distribution around, just by the monitoring to these dose characteristics points, this die body just can be set for the systematic parameter of the special CT equipment of mammary gland, to obtaining the situation that is uniformly distributed of dosage.
In addition, in specific implementation, above-mentioned thermoluminescent detector (TLD) can also further be demarcated through the stator of monolithic, is specially: repeatability, stability, energy and dose response to every a slice thermoluminescent detector (TLD) are measured.For instance, at several detector putting holes, can place 5 thermoluminescent detector (TLD)s in 2., by the meansigma methods of 5 thermoluminescent detector (TLD)s being obtained to the dose value that can represent this panel region, this method is also more surely leaned on; Due to the method for using stator to demarcate, also a slice thermoluminescent detector (TLD) can be placed in circular hole and measure, in actual use, can use single sheet measurement according to user demand, also can use multi-disc to measure by rational grouping.
In addition, above-mentioned mammary gland die body can further include dosiology and measures film and CT ionization chamber, and this dosiology measurement film can be placed on the central plane of the newborn body of described ellipse, for obtaining the dose distribution on this central plane;
CT ionization chamber, is arranged on the central axis of the newborn body of described ellipse, for obtaining the dosage on this central shaft, and for the measurement of dose calibration and CT dose index.
Above-mentioned mammary gland die body also can comprise mammary gland simulated slot in actual applications, for simulating the structure of breast duct or other mammary gland morphological characteristic, and inputs as required medicinal fluid, to realize the most real mammary gland simulation.Therefore this die body can be used for any need to use on three-dimensional incompressible mammary gland equipment, PET equipment as special in the mammary gland for breast cancer diagnosis.
The newborn body of above-mentioned ellipse can be selected close to the material of true mammary gland tissue and make, and specifically can be comprised of the mixed materials of 50% body of gland and 50% fat, and other materials that those skilled in the art can expect certainly also can meet the demands.
In sum, special mammary gland die body can be used for measuring and demarcate radiation dose that mammary gland is subject to and the distribution of dosage described in the embodiment of the present invention, is more conducive to control and the suffered radiation dose level of assessment mammary gland, improves breast disease diagnosis technology.
The above; only for the preferably specific embodiment of the present invention, but protection scope of the present invention is not limited to this, is anyly familiar with in technical scope that those skilled in the art disclose in the present invention; the variation that can expect easily or replacement, within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of claims.
Claims (6)
1. for a mammary gland die body for the special CT equipment of mammary gland, it is characterized in that, described mammary gland die body comprises oval newborn body, several detector putting holes, thermoluminescent detector (TLD), the first gim peg and the second gim peg, wherein:
The newborn body of described ellipse is divided into two by elliptical center plane, is divided into two oval hemisphere, and described several detector putting holes all embed in one of them oval hemisphere, and another oval hemisphere forms the shape of mammary gland for auxiliary described mammary gland die body;
The shape of described detector putting hole is set to circular hole or small column, and described thermoluminescent detector (TLD) is placed in described detector putting hole and carries out DATA REASONING;
Four jiaos of described the first gim peg is round angle, and air is overflowed from four angle seam gaps, for play effect fixing and buffering when two oval hemisphere merge;
Described the second gim peg, for two oval hemisphere are closely fixing, prevents that described mammary gland die body from coming off in CT scan.
2. the mammary gland die body for the special CT equipment of mammary gland as claimed in claim 1, it is characterized in that, described several detector putting holes further come interval according to the central plane of the newborn body of described ellipse to surperficial distance and arrange, and by the monitoring of the thermoluminescent detector (TLD) in these detector putting holes, obtain the situation that is uniformly distributed of mammary gland dosage and dosage.
3. the mammary gland die body for the special CT equipment of mammary gland as claimed in claim 1 or 2, is characterized in that,
Described thermoluminescent detector (TLD) is further demarcated through the stator of monolithic, is specially: repeatability, stability, energy and dose response to every a slice thermoluminescent detector (TLD) are measured.
4. the mammary gland die body for the special CT equipment of mammary gland as claimed in claim 1, is characterized in that, in described mammary gland die body, also comprises:
Dosiology is measured film, is placed on the central plane of the newborn body of described ellipse, for obtaining the dose distribution on this central plane;
CT ionization chamber, is arranged on the central axis of the newborn body of described ellipse, for obtaining the dosage on this central shaft, and for the measurement of dose calibration and CT dose index.
5. the mammary gland die body for the special CT equipment of mammary gland as claimed in claim 1, is characterized in that, in described mammary gland die body, also comprises:
Mammary gland simulated slot, for simulating the structure of breast duct, and inputs medicinal fluid as required.
6. the mammary gland die body for the special CT equipment of mammary gland as claimed in claim 5, is characterized in that, the newborn body of described ellipse is comprised of the mixed materials of 50% body of gland and 50% fat.
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| CN106847037A (en) * | 2017-04-05 | 2017-06-13 | 吉林大学 | A kind of body mould and its preparation for mammary gland Microcalcification clinical training |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104076310B (en) * | 2014-07-17 | 2017-01-11 | 中国科学院高能物理研究所 | Testing device for evaluating performance and dosage of special CT (computed tomography) equipment for mammary gland |
| CN105068105B (en) * | 2015-08-18 | 2017-09-26 | 浙江建安检测研究院有限公司 | Accelerator head leakage rediation method of testing |
| CN106581873B (en) * | 2016-12-07 | 2019-12-27 | 上海交通大学医学院附属第九人民医院 | Method for detecting radioactive dose |
| CN107348967A (en) * | 2017-07-06 | 2017-11-17 | 固安县朝阳生物科技有限公司 | Mammary gland die body |
| CN109875596A (en) * | 2019-03-27 | 2019-06-14 | 毕节市七星关区人民医院 | A kind of mammary gland die body for the dedicated CT equipment of mammary gland |
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| CN101045021B (en) * | 2007-04-26 | 2010-05-19 | 李保锴 | Administration type silica gel prothesis mamma |
| JP2010069241A (en) * | 2008-09-22 | 2010-04-02 | Fujifilm Corp | Tomographic breast imaging system |
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| CN101983033A (en) * | 2007-12-21 | 2011-03-02 | 科宁公司 | Method and apparatus for cone-beam CT imaging and image-guided procedures |
| JP2009183448A (en) * | 2008-02-06 | 2009-08-20 | Shimadzu Corp | Diagnostic system |
| US20100074400A1 (en) * | 2008-09-25 | 2010-03-25 | Fujifilm Corporation | Radiation imaging and therapy apparatus for breast |
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| CN106847037A (en) * | 2017-04-05 | 2017-06-13 | 吉林大学 | A kind of body mould and its preparation for mammary gland Microcalcification clinical training |
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