CN102641364A - Drug for treating constipation and preparation method thereof - Google Patents
Drug for treating constipation and preparation method thereof Download PDFInfo
- Publication number
- CN102641364A CN102641364A CN2012101393418A CN201210139341A CN102641364A CN 102641364 A CN102641364 A CN 102641364A CN 2012101393418 A CN2012101393418 A CN 2012101393418A CN 201210139341 A CN201210139341 A CN 201210139341A CN 102641364 A CN102641364 A CN 102641364A
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- CN
- China
- Prior art keywords
- medicine
- semen
- constipation
- fructus
- rhizoma atractylodis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000003814 drug Substances 0.000 title claims abstract description 27
- 206010010774 Constipation Diseases 0.000 title claims abstract description 22
- 229940079593 drug Drugs 0.000 title abstract description 7
- 238000002360 preparation method Methods 0.000 title description 2
- 239000007788 liquid Substances 0.000 claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 5
- 239000006187 pill Substances 0.000 claims abstract description 4
- 239000002775 capsule Substances 0.000 claims abstract description 3
- 239000008187 granular material Substances 0.000 claims abstract description 3
- 238000002347 injection Methods 0.000 claims abstract description 3
- 239000007924 injection Substances 0.000 claims abstract description 3
- 239000002674 ointment Substances 0.000 claims abstract description 3
- 239000000843 powder Substances 0.000 claims abstract description 3
- 239000003826 tablet Substances 0.000 claims abstract description 3
- 210000000582 semen Anatomy 0.000 claims description 14
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 241000522254 Cassia Species 0.000 claims description 4
- 241000555712 Forsythia Species 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 2
- 241000132012 Atractylodes Species 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 235000000228 Citrus myrtifolia Nutrition 0.000 abstract 1
- 235000016646 Citrus taiwanica Nutrition 0.000 abstract 1
- 241000555682 Forsythia x intermedia Species 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 235000003805 Musa ABB Group Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 244000236658 Paeonia lactiflora Species 0.000 abstract 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 abstract 1
- 235000015266 Plantago major Nutrition 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 3
- 230000013872 defecation Effects 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a drug for treating constipation. Bighead atractylodes rhizome, forsythia, white peony root, plantain seed, citrus aurantium, cassia seed and licorice and other herbs are used as raw materials, are decorated through a slow fire repeatedly, the drug liquid is concentrated into thick paste, and then the thick paste is added with conventional excipients to be made into clinically acceptable tablets, capsules, pills, granules, powders, injection or ointment. The drug provided by the invention can be used for treating various types of constipation.
Description
Technical field
The present invention relates to a kind of medicine of treating constipation, specially referring to a kind of is the medicine of the treatment constipation of feedstock production with the Chinese herbal medicine, the invention still further relates to the method for preparing of this medicine.
Background technology
The main clinical manifestation of constipation is that defecation frequency reduces, the feces amount reduces, feces is dry and hard, defecation effort etc.At present, because the continuous change of people's dietary structure and the rule of life that some are bad, it is more and more to suffer from the constipation people, and constipation has brought very big misery to the patient, treats the comparison difficulty.At present, the Western medicine of treatment constipation is a lot, but the most drug therapeutic effect is poor, and treats shortcomings such as high, that side effect is big in addition, when serious even influence patient health.In addition, also have the Chinese medicines of a lot of treatment constipation, but shortcoming such as great majority have that therapeutic effect is poor, cure rate is low and treatment cycle is long.
Summary of the invention
The present invention aims to provide the medicine of the treatment constipation that a kind of cure rate is high, cost is low, have no side effect.
The method for preparing that this medicine is provided is another goal of the invention of the present invention.
Medicine of the present invention is to be processed by the raw material of following mass ratio:
The Rhizoma Atractylodis Macrocephalae 8-15 Fructus Forsythiaes 10-20 Radix Paeoniae Albas 8-12 Semen Plantaginiss 10-15
Fructus Aurantii Immaturus 10-20 Semen Cassiaes 8-15
Radix Glycyrrhizae 8-15
Specifically process by the raw material of following mass ratio:
The Rhizoma Atractylodis Macrocephalae 10 Fructus Forsythiaes 15 Radix Paeoniae Albas 11 Semen Plantaginiss 12
Fructus Aurantii Immaturus 15 Semen Cassiaes 13
Radix Glycyrrhizae 12
The method for preparing of medicine of the present invention is:
The clear water that the Rhizoma Atractylodis Macrocephalae, Fructus Forsythiae, the Radix Paeoniae Alba, Semen Plantaginis, Fructus Aurantii Immaturus, Semen Cassiae and Radix Glycyrrhizae is added 60-130 weight portions; 0.5-1.5 hours at a simmer, fry in shallow oil 3 times repeatedly after, take out medicinal residues; Marmite is put in 3 medicinal liquid mixing to be fried in shallow oil 2-4 hours; Medicinal liquid is condensed into the thick paste shape, adds conventional adjuvant then, process tablet, capsule, pill, granule, powder, injection or the unguentum of clinical acceptance.
Addition complementation and synergism are arranged between each medicine in the prescription of the present invention, can effectively treat constipation.
The present invention is that the inventor is through research repeatedly; Progressively improve; A kind of curative effect of last success is treated the medicine of constipation preferably; For showing the therapeutic effect of medicine of the present invention to constipation, the constipation patient that the present invention takes this medicine to 317 examples has carried out clinical observation, and constipation patient 315 examples of selecting to have comparability are as matched group.Treatment group patient takes medicine twice of the present invention every day, and each once once takes 5 gram medicines sooner or later, and the matched group patient takes the oral drugs of conventional therapy constipation.Treat after one month, therapeutic outcome is seen table 1
Table 1 treatment group and treatment of control group be synopsis as a result
| ? | Cure | Effectively | Cure rate | Effective percentage |
| The treatment group | 271 examples | 292 examples | 85.49% | 92.11% |
| Matched group | 203 examples | 178 examples | 64.44% | 56.51% |
The treatment group is compared matched group and is had higher cure rate and effective percentage, thinks thus, and Drug therapy constipation of the present invention has effect preferably, and observes through one month treatment, takes medicine of the present invention and any toxic and side effects do not occur.
The specific embodiment
Below in conjunction with embodiment the present invention is done further explain, but do not constitute any restriction of the present invention.
Embodiment 1
Prepare raw material (kg) according to following weight:
The Rhizoma Atractylodis Macrocephalae 1.0, Fructus Forsythiae 1.0, the Radix Paeoniae Alba 1.5, Semen Plantaginis 2.0, Fructus Aurantii Immaturus 0.8, Semen Cassiae 1.2 and Radix Glycyrrhizae 1.3.
Above-mentioned 8.8kg Chinese herbal medicine is put into marmite, adds the clear water of 9.5kg, 1.5 hours at a simmer, fry in shallow oil 3 times repeatedly after; Take out medicinal residues, marmite is put in 3 medicinal liquid mixing again fried in shallow oil 3.5 hours, medicinal liquid is condensed into the thick paste shape, add refined honey then; Mix homogeneously is processed big honeyed pills, gets finished product after the packing.
Embodiment 2
Prepare raw material (kg) according to following weight:
The Rhizoma Atractylodis Macrocephalae 1.2, Fructus Forsythiae 1.1, the Radix Paeoniae Alba 1.5, Semen Plantaginis 2.0, Fructus Aurantii Immaturus 1.0, Semen Cassiae 1.2 and Radix Glycyrrhizae 1.4.
Above-mentioned 9.4kg Chinese herbal medicine is put into marmite, add the clear water of 10.5kg, 1.5 hours at a simmer; After frying in shallow oil 3 times repeatedly; Take out medicinal residues, marmite is put in 3 medicinal liquid mixing again fried in shallow oil 3 hours, medicinal liquid is condensed into the thick paste shape; With the oven dry of thick paste shape medicine, the grinding, encapsulated of gained, get finished product after the packing then.
Claims (3)
1. medicine of treating constipation is characterized in that said medicine is to be processed by the raw material of following mass ratio:
The Rhizoma Atractylodis Macrocephalae 8-15 Fructus Forsythiaes 10-20 Radix Paeoniae Albas 8-12 Semen Plantaginiss 10-15
Fructus Aurantii Immaturus 10-20 Semen Cassiaes 8-15
Radix Glycyrrhizae 8-15.
2. the medicine of treatment constipation according to claim 1 is characterized in that said medicine is to be processed by the raw material of following mass ratio:
The Rhizoma Atractylodis Macrocephalae 10 Fructus Forsythiaes 15 Radix Paeoniae Albas 11 Semen Plantaginiss 12
Fructus Aurantii Immaturus 15 Semen Cassiaes 13
Radix Glycyrrhizae 12.
3. the method for preparing of the medicine of treatment constipation according to claim 1; It is characterized in that this method adds the Rhizoma Atractylodis Macrocephalae, Fructus Forsythiae, the Radix Paeoniae Alba, Semen Plantaginis, Fructus Aurantii Immaturus, Semen Cassiae and Radix Glycyrrhizae in the clear water of 60-130 weight portions; 0.5-1.5 hours at a simmer, fry in shallow oil 3 times repeatedly after, take out medicinal residues; Marmite is put in 3 medicinal liquid mixing to be fried in shallow oil 2-4 hours; Medicinal liquid is condensed into the thick paste shape, adds conventional adjuvant then, process tablet, capsule, pill, granule, powder, injection or the unguentum of clinical acceptance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101393418A CN102641364A (en) | 2012-05-08 | 2012-05-08 | Drug for treating constipation and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101393418A CN102641364A (en) | 2012-05-08 | 2012-05-08 | Drug for treating constipation and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102641364A true CN102641364A (en) | 2012-08-22 |
Family
ID=46654608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101393418A Pending CN102641364A (en) | 2012-05-08 | 2012-05-08 | Drug for treating constipation and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102641364A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104286311A (en) * | 2014-10-29 | 2015-01-21 | 李娴 | A Herbal Tea for Constipation |
| CN104721333A (en) * | 2015-02-27 | 2015-06-24 | 李晓枫 | Traditional Chinese medicine composition for treating constipation |
| CN104983925A (en) * | 2015-07-29 | 2015-10-21 | 张光泉 | Prescription for treating constipation |
| CN105079433A (en) * | 2015-08-28 | 2015-11-25 | 南京正宽医药科技有限公司 | Medicinal preparation for treating constipation |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613362B2 (en) * | 2002-01-08 | 2003-09-02 | Renew Life Formulas, Inc. | Herbal formulation which acts as an intestinal bowel soother |
| CN1748765A (en) * | 2004-09-17 | 2006-03-22 | 鲁南制药集团股份有限公司 | Composition with catharsis and toxin expelling, fat reducing and weight reducing function and preparing method |
| CN101024033A (en) * | 2007-03-29 | 2007-08-29 | 李永红 | Dral Chinese medicine composition medicine for treating constipation |
| CN101129552A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating chronic functional constipation |
| CN101537108A (en) * | 2009-04-08 | 2009-09-23 | 杨泗兴 | Composition with functions of defaecation and detoxification, skin care and freckle dispelling, and preparation method thereof |
-
2012
- 2012-05-08 CN CN2012101393418A patent/CN102641364A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613362B2 (en) * | 2002-01-08 | 2003-09-02 | Renew Life Formulas, Inc. | Herbal formulation which acts as an intestinal bowel soother |
| CN1748765A (en) * | 2004-09-17 | 2006-03-22 | 鲁南制药集团股份有限公司 | Composition with catharsis and toxin expelling, fat reducing and weight reducing function and preparing method |
| CN101024033A (en) * | 2007-03-29 | 2007-08-29 | 李永红 | Dral Chinese medicine composition medicine for treating constipation |
| CN101129552A (en) * | 2007-08-27 | 2008-02-27 | 尹克华 | Traditional Chinese medicine for treating chronic functional constipation |
| CN101537108A (en) * | 2009-04-08 | 2009-09-23 | 杨泗兴 | Composition with functions of defaecation and detoxification, skin care and freckle dispelling, and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 健康帮女郎: "如何治疗便秘", 《太平洋女性网》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104286311A (en) * | 2014-10-29 | 2015-01-21 | 李娴 | A Herbal Tea for Constipation |
| CN104721333A (en) * | 2015-02-27 | 2015-06-24 | 李晓枫 | Traditional Chinese medicine composition for treating constipation |
| CN104983925A (en) * | 2015-07-29 | 2015-10-21 | 张光泉 | Prescription for treating constipation |
| CN105079433A (en) * | 2015-08-28 | 2015-11-25 | 南京正宽医药科技有限公司 | Medicinal preparation for treating constipation |
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120822 |
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| WD01 | Invention patent application deemed withdrawn after publication |