CN102697476A - OCT (optical coherence tomography) cholecystoscope system - Google Patents
OCT (optical coherence tomography) cholecystoscope system Download PDFInfo
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- CN102697476A CN102697476A CN2012100175064A CN201210017506A CN102697476A CN 102697476 A CN102697476 A CN 102697476A CN 2012100175064 A CN2012100175064 A CN 2012100175064A CN 201210017506 A CN201210017506 A CN 201210017506A CN 102697476 A CN102697476 A CN 102697476A
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- laser doppler
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- 238000012014 optical coherence tomography Methods 0.000 title abstract description 61
- 238000012545 processing Methods 0.000 claims abstract description 32
- 210000000232 gallbladder Anatomy 0.000 claims description 43
- 230000003287 optical effect Effects 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 9
- 239000013307 optical fiber Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 238000003384 imaging method Methods 0.000 claims description 6
- 239000007779 soft material Substances 0.000 claims description 5
- 230000008676 import Effects 0.000 claims description 3
- 210000004204 blood vessel Anatomy 0.000 abstract description 7
- 238000003745 diagnosis Methods 0.000 abstract description 6
- 230000003902 lesion Effects 0.000 abstract 1
- 231100000915 pathological change Toxicity 0.000 description 7
- 230000036285 pathological change Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 238000003325 tomography Methods 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000002301 combined effect Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 238000012797 qualification Methods 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 241001269238 Data Species 0.000 description 1
- 210000002565 arteriole Anatomy 0.000 description 1
- 210000003363 arteriovenous anastomosis Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001736 capillary Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 238000010205 computational analysis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000011846 endoscopic investigation Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000000264 venule Anatomy 0.000 description 1
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Abstract
The invention belongs to the field of medical instruments, and particularly discloses a Doppler laser OCT (optical coherence tomography) cholecystoscope system, which comprises a cholecystoscope, a cold light source main main unit and a camera main unit, wherein the cold light source main unit and the camera main unit are connected with the cholecystoscope system. The cholecystoscope is provided with a Doppler laser data acquisition module and an OCT data acquisition module and is connected with a Doppler processing main unit used for analyzing data acquired by the Doppler laser data acquisition module and an OCT processing main unit used for analyzing data acquired by the OCT data acquisition module. Since the Doppler laser data acquisition module and the OCT data acquisition module are integrated on the same telescopic head of a combined module and used with the Doppler processing main unit and the OCT processing main unit for processing, more accurate dynamic images and more precise sectional lesion images of blood vessels on surfaces of gall blader walls can be acquired, and a more precise data support can be supplied for doctors to make diagnosis and treatment.
Description
Technical field
The invention belongs to field of medical appliances, be specifically related to a kind of laser doppler OCT cholecystoscope system.
Background technology
The gallbladder mirror is diagnosing patients gallbladder pathological changes, assessment gallbladder function, the accuracy rate that improves operation and the important medical apparatus and instruments of success rate.
Doppler principle all is used widely in every field, utilizes the Doppler effect of laser beam in the industry, is used for the speed of Measuring Object, and its degree of accuracy is high; Medically utilize hyperacoustic Doppler effect, observation patient body situation.The laser doppler technology slowly also gets into medical domain at present; Utilize the Doppler effect of laser to measure the microcirculation blood flow of various tissues and organ with the mode of noinvasive or Wicresoft; In addition can also do series of analysis calculates; Comprise microcirculatory hemodynamics variation, and heart is beated synchronously even double pulse etc., accomplish the purpose of accurate monitoring.
Equally; OCT (Optical Coherence Tomography; Optical Coherence Tomography Imaging Technology) utilizes the weak coherent light principle of interference; Detect the backscatter signals of tested tissue different depth, and obtain organizing two dimension or three dimensional depth structural images, have characteristics such as radiationless, non-intruding, high-resolution and high detection sensitivity through scanning.
The OCT technology has obtained effective application in ophthalmologic examination, and gets involved in the human organ, the microminiaturization of OCT technology is applied to intraorganic disease detect, and is not still effectively carried out at present.
But at present, in the gallbladder mirror, still there are not fine application laser doppler technology and OCT technology.If the gallbladder mirror can be gathered the advantage of laser doppler technology and OCT technology, accurate more dynamic image of top layer blood vessel and meticulousr tomography pathological changes image with obtaining between gallbladder wall further improve the accuracy of diagnosis and the success rate of treatment.
Therefore, design is a kind of extremely urgent with the cholecystoscope system that laser doppler is technological, OCT is technological to be used in combination with the gallbladder mirror.
Summary of the invention
The object of the present invention is to provide a kind of laser doppler OCT cholecystoscope system; The advantage of set laser doppler technology and OCT technology; Accurate more dynamic image of top layer blood vessel and meticulousr tomography pathological changes image with obtaining between gallbladder wall further improve the accuracy of diagnosis and the success rate of treatment.
For realizing the foregoing invention purpose, technical scheme that the present invention adopts is following:
A kind of laser doppler OCT cholecystoscope system; Comprise gallbladder mirror and the cold light source main frame that is connected with this gallbladder mirror and shooting main frame; Said gallbladder mirror is provided with laser doppler data acquisition module and OCT data acquisition module; On said gallbladder mirror, also be connected with Doppler's processing host that the data that said laser doppler data acquisition module is collected are carried out analyzing and processing, on said gallbladder mirror, also be connected with the OCT processing host that the data that said OCT data acquisition module is collected are carried out analyzing and processing.
In the described laser doppler OCT cholecystoscope system, its laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
In the described laser doppler OCT cholecystoscope system, its Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
In the described laser doppler OCT cholecystoscope system, its gallbladder mirror includes a work end; Said laser doppler data acquisition module and OCT data acquisition module are arranged on the gallbladder mirror; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
In the described laser doppler OCT cholecystoscope system, the diameter of its telescopic head is smaller or equal to 3 millimeters.
In the described laser doppler OCT cholecystoscope system, on the first end of said work end, also be provided with optical fibers, optical lens, outlet, water inlet and apparatus and import and export.
In the described laser doppler OCT cholecystoscope system, its apparatus is imported and exported diameter more than or equal to 3 millimeters, and said water inlet and outlet diameter are more than or equal to 1 millimeter.
Gallbladder mirror according to the invention can be divided into soft and two kinds of forms of hard with the character of its work end:
One, its work end is processed by soft material, and this soft material is selected materials such as flexible medical fibre for use.The diameter of this soft work end smaller or equal to 12 millimeters, length smaller or equal to 500 millimeters; It is 1.5～3.0 millimeters CCD optical lens that optical lens on this work end adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.Certainly, the gallbladder mirror of this kind structure also comprises conventional instrument channel, exhalant canal, intake tunnel, operating grip, control module, data connector etc.
Two, its work end is processed by hard material, and this hard material is selected hard materials such as medical stainless steel for use.The diameter of said work end is 250～300 millimeters smaller or equal to 12 millimeters, length; The focal length of the optical lens on the said work end is less than 3 millimeters; In order to prevent to damage mucosal tissue, the first end of this hard work end is blunt type.Certainly, the gallbladder mirror of this kind structure also comprises conventional cold light source joint, data connector, control module, instrument channel, intake tunnel and exhalant canal etc.
Its principle of the present invention is at integrated laser doppler module of endoscopic technique and OCT module; Make the doctor can obtain the laser doppler image and the OCT image in patient affected part simultaneously through once performing the operation; Accomplish without any letup, reduce the diagnosis basis that damages and obtain enriching more.The laser doppler technology is to utilize the doppler principle of light wave; Utilize laser beam irradiation and write down the light of reflection, transmission, scattering and the data behind the reference light frequency modulation; Come accurately to survey the blood flow velocity and calculating blood flow flow of blood vessel, the laser doppler technology has than the more accurate certainty of measurement of doppler technique; The OCT module utilizes means of optical coherence tomography, carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.The vascular flow of blood vessel and tissue substance thereof is dynamically schemed between gallbladder wall, and the tomography pathological changes image between tachogram and gallbladder wall etc. are for doctor's diagnosis provides more accurate accurate data support.
Compared with prior art, the invention has the beneficial effects as follows:
The laser doppler measuring technique has than the more accurate characteristics of doppler technique, can obtain blood vessel accurate more dynamic image in top layer between gallbladder wall; OCT techniques make use means of optical coherence tomography carries out the fault imaging that resolution is carried out with micron level, obtains meticulous tomography pathological changes image.Two images perhaps are simultaneously displayed in the display respectively, can improve the accuracy of diagnosis patient gallbladder pathological changes, assessment gallbladder function, further improve the accuracy rate and the success rate of operation.
Description of drawings
The picture that this description of drawings provided is used for auxiliary to further understanding of the present invention, constitutes the application's a part, does not constitute to improper qualification of the present invention, in the accompanying drawings:
Fig. 1 is a system structure sketch map of the present invention;
Fig. 2 comprises the gallbladder mirror structural representation of hard work end for the present invention;
Fig. 3 is the gallbladder mirror structural representation that the present invention includes soft work end;
Fig. 4 is the local structure for amplifying sketch map of the first end of work of the present invention end.
Diagram:
1, gallbladder mirror 2, cold light source main frame
3, shooting main frame 4, laser doppler processing host
5, OCT processing host 6, operation keyboard or handheld device
7, Doppler and OCT monitor 8, endoscope's monitor
11, work end 12, cold light source joint
13, data connector 14, instrument channel
15, intake tunnel 16, exhalant canal
17, control module 18, operating grip
111, first end 1111, optical fibers
1112, optical lens 1113, apparatus are imported and exported
1114, water inlet 1115, outlet
1116, telescopic head 11161, Laser emission end
11162, laser pick-off end 11163, OCT data acquisition module
11164, micromotor
The specific embodiment
To combine accompanying drawing and practical implementation method to specify the present invention below, be used for explaining the present invention in schematic enforcement of the present invention and explanation, but not as to qualification of the present invention.
As shown in Figure 1; Laser doppler OCT cholecystoscope system disclosed by the invention; Mainly comprise gallbladder mirror 1 and the cold light source main frame 2 that is connected with this gallbladder mirror 1, shooting main frame 3, laser doppler processing host 4, OCT processing host 5, also comprise operation keyboard or handheld device 6, Doppler and OCT monitor 7 and endoscope's monitor 8 these conventional input-output equipment certainly.
As shown in Figure 1, reduce cost in order to economize on resources, shared monitor-Doppler of laser doppler processing host and OCT processing host and OCT monitor 7 show through split screen in the present embodiment, can certainly use different monitors to be used for showing respectively.
Fig. 2 and 3 is for two kinds of different structure sketch maps of gallbladder mirror of the present invention:
As shown in Figure 2, its work end 11 is processed by hard material, and this hard material is selected hard materials such as medical stainless steel for use.The diameter of this work end 11 is 250～300 millimeters smaller or equal to 12 millimeters, length, and the focal length of the optical lens on the work end is less than 3 millimeters; In order to prevent to damage mucosal tissue, the first end of this hard work end is blunt type, and so-called blunt type is for there are stiff corner angle in head, such as circular, oval or other do not have the shape of stiff corner angle.Certainly, the gallbladder mirror of this kind structure also comprises conventional cold light source joint 12, data connector 13, control module 17, instrument channel 14, intake tunnel 15 and exhalant canal 16 etc.
As shown in Figure 3, its work end 11 is processed by soft material, and this soft material is selected materials such as flexible medical fibre for use.The diameter of this soft work end smaller or equal to 12 millimeters, length smaller or equal to 500 millimeters; It is 1.5～3.0 millimeters CCD optical lens that optical lens on this work end adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.Certainly, the gallbladder mirror of this kind structure also comprises conventional instrument channel 14, exhalant canal 16, intake tunnel 15, operating grip 18, control module 17, data connector 13 etc.
Fig. 4 is the local structure for amplifying sketch map of the first end 111 of work of the present invention end 11, and so-called first end promptly is the front end position, and its structure is specifically as shown in the figure:
This elder generation end 111 comprises optical fibers 1111 and is arranged at optical lens 1112, apparatus import and export 1113, water inlet 1114, outlet 1115 and the telescopic head 1116 on this optical fibers 1111 that this telescopic head 1116 comprises transparent outer cover and is installed in Laser emission end 11161, laser pick-off end 11162, OCT data acquisition module 11163 and the micromotor 11164 in the transparent outer cover.Wherein, Laser emission end 11161 constitutes the laser doppler data acquisition module with laser pick-off end 11162; Wherein, OCT data acquisition module 11163 comprises the conventional structures such as prism, GRIN Lens and optical fiber tissue that comprise; Wherein, telescopic head 1116 can stretch out the end face with withdrawal work end 11 under the effect of its micromotor 11164, also can at the uniform velocity rotate by 360 degree, observes with convenient.Wherein, use for ease, the diameter of telescopic head 1116 is smaller or equal to 3 millimeters, and apparatus is imported and exported 1113 diameters more than or equal to 3 millimeters, and water inlet 1114 and outlet 1115 diameters are more than or equal to 1 millimeter.
The present invention with laser doppler module (laser doppler data acquisition module) and OCT module (OCT data acquisition module) under not interferential situation each other; Design Treatment through microminiaturization; Be integrated on the telescopic head 1116 on the first end 111 that is positioned at work end 11; This telescopic head 1116 can be released the end face realization work in addition of work end 11 through the transmission of micromachine 11164, and the inoperative stage is through the transmission of micromachine 11164; In 11 end faces of withdrawal work end, to make the usefulness of protection.
Operation keyboard among the present invention or handheld device 6, its function are that laser doppler main frame and OCT processing host are controlled, and scan mode and display mode etc. such as are switched at effect.
Laser doppler data acquisition module among the present invention and the combined effect of laser doppler processing host; The laser doppler processing host is carried out analyzing and processing to the data that the doppler data acquisition module collects; Can measure the microcirculation blood flow of blood vessel between gallbladder wall; Whole microcirculatory perfusion amounts comprise that blood capillary, arteriole, venule and arteriovenous anastomosis prop up, and can monitor senior clinical datas such as microcirculatory hemodynamics variation through computational analysis.Described laser doppler processing host can carry powerful data base and powerful software test bag, to satisfy the different needs of the different purpose doctors of section.
OCT data acquisition module among the present invention and the combined effect of OCT processing host; Right gallbladder wall phantom data that the OCT data acquisition module collected of OCT processing host and Treatment Analysis in addition; The faultage image that display resolution carries out with micron level, and output to the display demonstration.
Gallbladder mirror among the present invention has possessed all optical observation functions of general gallbladder mirror; Among normal observation carries out or after; Can be through opening laser doppler processing host 4, OCT processing host 5 respectively or simultaneously; The laser doppler data acquisition module and the OCT data acquisition module that start on the telescopic head carry out laser doppler scanning and the observation of OCT tomoscan, and the telescopic head duration of work does not disturb the application of the common function of gallbladder mirror.
More than the technical scheme that the embodiment of the invention provided has been carried out detailed introduction; Used concrete example among this paper the principle and the embodiment of the embodiment of the invention are set forth, the explanation of above embodiment only is applicable to the principle that helps to understand the embodiment of the invention; Simultaneously, for one of ordinary skill in the art, according to the embodiment of the invention, the part that on the specific embodiment and range of application, all can change, in sum, this description should not be construed as limitation of the present invention.
Claims (9)
1. a laser doppler OCT cholecystoscope system comprises gallbladder mirror and the cold light source main frame that is connected with this gallbladder mirror and shooting main frame, it is characterized in that:
Said gallbladder mirror is provided with laser doppler data acquisition module and OCT data acquisition module;
On said gallbladder mirror, also be connected with Doppler's processing host that the data that said laser doppler data acquisition module is collected are carried out analyzing and processing;
On said gallbladder mirror, also be connected with the OCT processing host that the data that said OCT data acquisition module is collected are carried out analyzing and processing.
2. laser doppler OCT cholecystoscope system according to claim 1 is characterized in that:
Said laser doppler data acquisition module comprises Laser emission end and laser pick-off end, and said OCT data acquisition module comprises prism, GRIN Lens and optical fiber tissue.
3. laser doppler OCT cholecystoscope system according to claim 1 is characterized in that:
Said Doppler's processing host is connected a monitor or the shared monitor of split screen respectively with the OCT processing host.
4. according to each described laser doppler OCT cholecystoscope system of claim 1 to 3, it is characterized in that:
Said gallbladder mirror includes a work end;
Said laser doppler data acquisition module and OCT data acquisition module are arranged on the gallbladder mirror; Specifically: on the first end of said work end, be provided with one and can stretch out the telescopic head that rotates with withdrawal and 360 degree, said laser doppler data acquisition module and OCT data acquisition module just are arranged in the telescopic head.
5. laser doppler OCT cholecystoscope system according to claim 4 is characterized in that:
The diameter of said telescopic head is smaller or equal to 3 millimeters.
6. laser doppler OCT cholecystoscope system according to claim 4 is characterized in that:
On the first end of said work end, also being provided with optical fibers, optical lens, outlet, water inlet and apparatus imports and exports.
7. laser doppler OCT cholecystoscope system according to claim 6 is characterized in that:
Said apparatus is imported and exported diameter more than or equal to 3 millimeters, and said water inlet and outlet diameter are more than or equal to 1 millimeter.
8. laser doppler OCT cholecystoscope system according to claim 6 is characterized in that:
Said work end is processed by soft material, the diameter of this soft work end smaller or equal to 12 millimeters, length smaller or equal to 500 millimeters;
It is 1.5～3.0 millimeters CCD optical lens that said optical lens adopts focal length, the imaging size of the CCD chip of this CCD optical lens smaller or equal to 1/4th inches, valid pixel more than or equal to 480,000, the angle of view is more than or equal to 100 degree.
9. laser doppler OCT cholecystoscope system according to claim 6 is characterized in that:
Said work end is processed by hard material, and the first end of this hard work end is blunt type;
The diameter of said work end is 250～300 millimeters smaller or equal to 12 millimeters, length;
The focal length of the optical lens on the said work end is less than 3 millimeters.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012100175064A CN102697476A (en) | 2012-01-18 | 2012-01-18 | OCT (optical coherence tomography) cholecystoscope system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100175064A CN102697476A (en) | 2012-01-18 | 2012-01-18 | OCT (optical coherence tomography) cholecystoscope system |
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| CN102697476A true CN102697476A (en) | 2012-10-03 |
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| CN202426510U (en) * | 2012-01-18 | 2012-09-12 | 广州宝胆医疗器械科技有限公司 | Doppler laser OCT (optical coherence tomography) gall bladder lens system |
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2012
- 2012-01-18 CN CN2012100175064A patent/CN102697476A/en active Pending
Patent Citations (11)
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|---|---|---|---|---|
| CN85205102U (en) * | 1985-11-26 | 1986-12-17 | 薛络 | Z-formed, hard colonoscope composed of annularly distributed optical fibre and cold light source |
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Application publication date: 20121003 |