CN102824237B - A kind of thoracic aorta covered bracket - Google Patents
A kind of thoracic aorta covered bracket Download PDFInfo
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- CN102824237B CN102824237B CN201110157454.6A CN201110157454A CN102824237B CN 102824237 B CN102824237 B CN 102824237B CN 201110157454 A CN201110157454 A CN 201110157454A CN 102824237 B CN102824237 B CN 102824237B
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- individual pen
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- overlay film
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- 210000002376 aorta thoracic Anatomy 0.000 title claims abstract description 47
- 229910001385 heavy metal Inorganic materials 0.000 claims description 3
- 208000002251 Dissecting Aneurysm Diseases 0.000 abstract description 5
- 238000002324 minimally invasive surgery Methods 0.000 abstract description 3
- 238000001356 surgical procedure Methods 0.000 abstract description 3
- 206010002329 Aneurysm Diseases 0.000 abstract description 2
- 208000032843 Hemorrhage Diseases 0.000 description 7
- 210000000709 aorta Anatomy 0.000 description 7
- 208000007474 aortic aneurysm Diseases 0.000 description 6
- 208000014674 injury Diseases 0.000 description 6
- 230000008733 trauma Effects 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 210000004204 blood vessel Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000006073 displacement reaction Methods 0.000 description 3
- 210000002489 tectorial membrane Anatomy 0.000 description 3
- 208000025494 Aortic disease Diseases 0.000 description 2
- 101000579647 Penaeus vannamei Penaeidin-2a Proteins 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011229 interlayer Substances 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 229910000521 B alloy Inorganic materials 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 238000013475 authorization Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000036314 physical performance Effects 0.000 description 1
- -1 polyethylene terephthalate Polymers 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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- Prostheses (AREA)
Abstract
The present invention relates to the thoracic aorta covered bracket being used for the treatment of aneurysm of thoracic aorta and dissecting aneurysm in a kind of surgery Minimally Invasive Surgery, comprise: overlay film and the support be made up of multiple column individual pen, described overlay film adheres on the bracket and forms tubulose overlay film, multiple described column individual pen undulate, the near-end of described support is provided with bracing frame, described column individual pen comprises: first kind column individual pen and Equations of The Second Kind column individual pen, described first kind column individual pen and Equations of The Second Kind column individual pen are spaced apart on described tubulose overlay film, the waveform quantity of described first kind column individual pen is no less than the waveform quantity of described Equations of The Second Kind column individual pen, and the waveform of described first kind column individual pen is less than the waveform of described Equations of The Second Kind column individual pen.
Description
Technical field
The present invention relates to the overlay film frame being used for the treatment of aneurysm of thoracic aorta and dissecting aneurysm in a kind of surgery Minimally Invasive Surgery.
Background technology
Utilize prosthetic aortic overlay film frame implanted prosthetics to treat aortic aneurysm and dissecting aneurysm just more and more in surgery Minimally Invasive Surgery field, its method is: by induction system thinner for prosthetic aortic overlay film frame compression inlet pipe footpath, the seal wire previously implanted from external warp guides to aortic disease and discharges.Aorta tectorial membrane stent after release covers aortic disease part, block it and obtain fresh blood supply, make aortic aneurysm form thrombosis gradually, thus alleviate the compressing of aortic aneurysm to surrounding tissue, organ, and elimination causes the danger of massive hemorrhage because aortic aneurysm breaks.Aorta tectorial membrane stent, under elastic force effect own, is attached on aorta tube wall, manufactures the blood channel made new advances in pathological changes aorta vessel.When dissecting aneurysm, by the elastic dilatation of support, interlayer is oppressed, reach the object eliminating interlayer gradually.
What the thoracic aorta covered bracket existed in the market adopted is single kind wire rack mount circle, and is only provided with the detent mechanisms such as bare bracket in mount proximal end (one end near heart).This thoracic aorta covered bracket is adapt to the thicker feature of thoracic aorta, meet certain rigidity to reach the rear good support effect of release, it is comparatively large that the waveform of wire rack mount circle often designs, and this can bring following problem: overlay film frame arrives lesion locations because waveform is comparatively large, compliance is undesirable, not easily pass through aortic arch place (i.e. aorta comparatively macrobending place); If aorta tectorial membrane stent, in the release of aortic arch place, is easily squeezed and causes distortion, discounting etc. thus make blood channel cross section diminish, even cause overlay film frame near-end internal hemorrhage due to trauma; When overlay film frame discharges at aortic arch place, because radical elasticity is comparatively large, there is secondary gap in easy injured blood vessel wall in aorta situation with dissection; Overlay film frame far-end (one end away from heart) place due to without fixture, to be easily subjected to displacement, distortion etc.If Waveform Design is less, then can be inadequate because of rigidity, good supporting role can not be played, effectively can not cover aortic aneurysm.
Authorization Notice No. is CN2675083Y, the applying date is on January 6th, 2004, name is called that the patent of invention description of Y type large artery trunks overlay film frame discloses a kind of Y type large artery trunks overlay film frame, it is made up of a main part and two components, main part and component comprise the tubulose overlay film of support that the column individual pen containing multiple waveform that multiple B alloy wire makes forms and Y shape, support and overlay film are sewed up by medical surgical sewing thread, it is characterized in that, said column individual pen comprises first kind column individual pen, Equations of The Second Kind column individual pen and the 3rd class column individual pen, after first kind column spread of single circle blade, all on the same line, all troughs also all on the same line for all crests of waveform, after Equations of The Second Kind column spread of single circle blade, all on the same line, all troughs also all on the same line for all crests of waveform, Equations of The Second Kind column individual pen wave number is more than first kind column individual pen, and waveform is less than first kind column individual pen, after 3rd class column spread of single circle blade, all on the same line, all crests are outside from the crest of centre, raise gradually successively for all troughs, wherein first kind column individual pen is positioned at the mid portion of overlay film frame main body, and Equations of The Second Kind column individual pen is positioned at the original position of overlay film frame main body overlay film section, and the 3rd class column individual pen is positioned at two branches of overlay film frame, this overlay film frame has integral structure, the design of near-end anti-internal hemorrhage due to trauma, branch bend the features such as compliance is better.But because its main body overlay film frame part adopts single kind wire rack mount circle, still can not solve that overlay film frame not easily passs through aortic arch place, being easily squeezed when discharging at aortic arch place causes distortion, discounting etc. thus make the problems such as blood channel cross section diminishes.
Summary of the invention
Technical problem to be solved by this invention there is the defect such as distortion, discounting, internal hemorrhage due to trauma, injured blood vessel wall and far-end is subjected to displacement, distortion after thoracic aorta covered bracket of the prior art not easily passs through aortic arch place, release.
For solving the problems of the technologies described above, the invention provides a kind of thoracic aorta covered bracket, described thoracic aorta covered bracket have employed the tinsel column individual pen of many specifications, there is higher compliance, be easy to bending, pass through property in art good, not easily distortion, discounting upon discharge, overlay film frame near-end (one end near heart) has anti-internal hemorrhage due to trauma to design, and radical elasticity is moderate, not easily injured blood vessel wall; Overlay film frame far-end (one end away from heart) place is provided with fixture.
The technical solution used in the present invention is:
A kind of thoracic aorta covered bracket, comprising:
Overlay film and the support be made up of multiple column individual pen, described overlay film adheres on the bracket and forms the overlay film frame of tubulose, multiple described column individual pen undulate, and the near-end of described overlay film frame is provided with bracing frame, it is characterized in that,
Described column individual pen comprises:
First kind column individual pen and Equations of The Second Kind column individual pen, described first kind column individual pen and Equations of The Second Kind column individual pen are in being in interval alternative distribution on described overlay film, the waveform quantity of described first kind column individual pen is no less than the waveform quantity of described Equations of The Second Kind column individual pen, and the waveform of described first kind column individual pen is less than the waveform of described Equations of The Second Kind column individual pen; Support frame as described above is Equations of The Second Kind column individual pen.
Preferably, the one or both ends of described overlay film frame are provided with one the 3rd class column individual pen, and the waveform quantity of described 3rd class column individual pen is no less than the waveform quantity of described first kind column individual pen.
Preferably, the other end away from described overlay film frame near-end is provided with a bracing frame, and support frame as described above is Equations of The Second Kind column individual pen.
Preferably, described Equations of The Second Kind column individual pen diameter wiry is not less than described first kind column individual pen diameter wiry.
Preferably, described Equations of The Second Kind column individual pen diameter wiry is not less than described 3rd class column individual pen diameter wiry.
Described first kind column individual pen, Equations of The Second Kind column individual pen, the 3rd class column individual pen all use linear slit outside described overlay film.
Described each column individual pen interval within the scope of described overlay film is equal.
The crest plane at least three crest places of described column individual pen is non-intersect in overlay film with the trough plane at least three trough places of the described column individual pen be adjacent, and non-intersect in overlay film with the crest plane at least three crest places of the described column individual pen be adjacent.
Described overlay film is also sewed with the developing parts be made up of heavy metal.
The present invention compared with prior art, has following beneficial effect:
1, the Equations of The Second Kind column individual pen waveform of thoracic aorta covered bracket of the present invention is large, and column individual pen wire diameter is comparatively large, and rigidity is comparatively large, can provide enough support forces; First kind column individual pen waveform is less, column individual pen wire diameter is thinner, compliance is better, by with Equations of The Second Kind column individual pen in being in interval alternative distribution in tubulose overlay film, the rigidity of its compliance and Equations of The Second Kind column individual pen is complementary, can improve the compliance of thoracic aorta covered bracket entirety, makes thoracic aorta covered bracket easily arrive lesion locations by aortic arch place, not easily distortion after the release of aortic arch place, discounting, not easily cause overlay film frame near-end internal hemorrhage due to trauma; And because the compliance of overlay film frame entirety improves, radical elasticity is moderate, not easily injured blood vessel wall.
2, the wave number of the 3rd class column individual pen of the end setting of thoracic aorta covered bracket of the present invention is many, makes overlay film frame have good adherent effect in end, can play good sealing function, not easily internal hemorrhage due to trauma occurs after thoracic aorta covered bracket is discharged.
3, by arranging Equations of The Second Kind column individual pen at overlay film frame far-end, overlay film frame far-end can be made not easily to be subjected to displacement, to be out of shape.
To sum up, by this kind of structure, the adaptability of thoracic aorta covered bracket can be improved, reduce operating difficulty, increase success rate of operation, shorten the recovery from illness cycle of postoperative patient.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the present invention is further described.
Fig. 1 is the schematic diagram of the first embodiment of thoracic aorta covered bracket of the present invention.
Fig. 2 is the schematic diagram of the second embodiment of thoracic aorta covered bracket of the present invention.
Fig. 3 is the schematic diagram of the third embodiment of thoracic aorta covered bracket of the present invention.
Fig. 4 is the schematic diagram of thoracic aorta covered bracket of the present invention three kinds of bracket loops.
Detailed description of the invention
Embodiment 1
Be illustrated in figure 1 the thoracic aorta covered bracket of the first embodiment, comprise one section of overlay film be made up of fibrous material 1 and some disposed thereon first kind column individual pen 3, Equations of The Second Kind column individual pen 4 and the 3rd class column individual pens 2 made with compatible, corrosion-resistant and that mechanical and physical performance the is good tinsel of raw body.Respectively arrange a 3rd class column individual pen 2 at the two ends of thoracic aorta covered bracket, its wave height can be taken as 7.5mm, and wire diameter is taken as 0.013 ", wave number is taken as 12; Six first kind column individual pens 3 and six Equations of The Second Kind column individual pens 4 have been arranged alternately in the centre of thoracic aorta covered bracket, the interval that arranges of each column individual pen is 5mm, the wave height of first kind column individual pen 3 can be taken as 3mm, and wire diameter is taken as 0.013 ", wave number is taken as 11; The wave height of Equations of The Second Kind column individual pen 4 is taken as 5mm, and wire diameter is taken as 0.017 ", wave number is taken as 6.Each column individual pen is made by Nitinol is bending, and the both ends of column individual pen are telescopic joint by rustless steel.The material of overlay film can adopt PET(polyethylene terephthalate), diameter is taken as 36mm, and length is taken as 200mm.Be provided with an Equations of The Second Kind column individual pen 4 at overlay film frame near-end (near heart one end), be of a size of 3mm with the axial overlap of overlay film 1.The developing parts 5 that heavy metal is made also is provided with at the two ends of overlay film frame.The diameter wiry of each column individual pen, also can under the prerequisite meeting the object of the invention, value between 0.012 "-0.020 ".The crest plane at least three crest places of described first kind column individual pen is non-intersect in overlay film with the trough plane at least three trough places of the Equations of The Second Kind column individual pen be adjacent, and (these two crest planes can be parallel with trough plane, also can be not parallel, can not intersect in overlay film time not parallel), and with the crest plane at least three crest places of column individual pen described in another Equations of The Second Kind column be adjacent, non-intersect in overlay film (these two crest planes can be parallel with trough plane, also can be not parallel, can not intersect in overlay film time not parallel), the crest plane at least three crest places of described Equations of The Second Kind column individual pen is non-intersect in overlay film with the trough plane at least three trough places of the first kind column individual pen be adjacent, and (these two crest planes can be parallel with trough plane, also can be not parallel, can not intersect in overlay film time not parallel), and with the crest plane at least three crest places of column individual pen described in another first kind column be adjacent, non-intersect in overlay film (these two crest planes can be parallel with trough plane, also can be not parallel, can not intersect in overlay film time not parallel).
Embodiment 2
Be illustrated in figure 2 the thoracic aorta covered bracket of the second embodiment, the length of overlay film 1 is taken as 210mm, can be arranged alternately 7 first kind column individual pens 3 and 6 Equations of The Second Kind column individual pens 4 in the middle of overlay film 1.First, thoracic aorta covered bracket two ends column individual pen and second column individual pen interval can be taken as 2.5mm, and all the other intervals can be taken as 5mm.All the other are with the first embodiment.
Embodiment 3
Be illustrated in figure 3 the thoracic aorta covered bracket of the third embodiment, on the basis of the thoracic aorta covered bracket of the second embodiment, arrange an Equations of The Second Kind column individual pen 4 vertically at the far-end (one end away from heart) of thoracic aorta covered bracket, column individual pen 4 and overlay film 1 axial overlap size are no more than 3mm.
Be illustrated in figure 4 the schematic diagram of thoracic aorta covered bracket of the present invention three kinds of column individual pens.Wherein each size of first kind column individual pen 3, Equations of The Second Kind column individual pen 4 and the 3rd class column individual pen 2 can be determined according to the feature of patient, and the two ends of each column individual pen connect with rustless steel sleeve pipe 6.
Embodiment is not limited to aforementioned, any that make use of principle of the invention manufacture without approval with shape of the present invention and/or the therapy equipment constructing same or analogous aortic aneurysm and dissecting aneurysm all form infringement to right of the present invention.
Claims (8)
1. a thoracic aorta covered bracket, comprising:
Overlay film and the support be made up of multiple column individual pen, described overlay film adheres on the bracket and forms the overlay film frame of tubulose, multiple described column individual pen undulate, and the near-end of described overlay film frame is provided with bracing frame, it is characterized in that,
Described column individual pen comprises:
First kind column individual pen and Equations of The Second Kind column individual pen, described first kind column individual pen and Equations of The Second Kind column individual pen are in being in interval alternative distribution on described overlay film, and described first kind column individual pen and described Equations of The Second Kind column individual pen do not connect, the waveform quantity of described first kind column individual pen is no less than the waveform quantity of described Equations of The Second Kind column individual pen, and the waveform of described first kind column individual pen is less than the waveform of described Equations of The Second Kind column individual pen; Support frame as described above is Equations of The Second Kind column individual pen, and the one or both ends of described overlay film frame are provided with one the 3rd class column individual pen, and the waveform quantity of described 3rd class column individual pen is no less than the waveform quantity of described first kind column individual pen.
2. thoracic aorta covered bracket according to claim 1, is characterized in that,
The other end away from described overlay film frame near-end is provided with a bracing frame, and the bracing frame that the described other end is provided with is Equations of The Second Kind column individual pen.
3. thoracic aorta covered bracket according to claim 1, is characterized in that,
Described Equations of The Second Kind column individual pen diameter wiry is not less than described first kind column individual pen diameter wiry.
4. thoracic aorta covered bracket according to claim 3, is characterized in that,
Described Equations of The Second Kind column individual pen diameter wiry is not less than described 3rd class column individual pen diameter wiry.
5. thoracic aorta covered bracket according to claim 1, is characterized in that, described first kind column individual pen, Equations of The Second Kind column individual pen, the 3rd class column individual pen all use linear slit outside described overlay film.
6. thoracic aorta covered bracket according to claim 1, is characterized in that, the described each column individual pen interval within the scope of described overlay film is equal.
7. thoracic aorta covered bracket according to claim 1, is characterized in that,
The crest plane at least three crest places of described first kind column individual pen is non-intersect in overlay film with the trough plane at least three trough places of the described Equations of The Second Kind column individual pen be adjacent, and non-intersect in overlay film with the crest plane at least three crest places of the described Equations of The Second Kind column individual pen be adjacent; Or
The crest plane at least three crest places of described Equations of The Second Kind column individual pen is non-intersect in overlay film with the trough plane at least three trough places of the described first kind column individual pen be adjacent, and non-intersect in overlay film with the crest plane at least three crest places of the described first kind column individual pen be adjacent.
8., according to the arbitrary described thoracic aorta covered bracket of claim 1-7, it is characterized in that, described overlay film is sewed with the developing parts be made up of heavy metal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110157454.6A CN102824237B (en) | 2011-06-13 | 2011-06-13 | A kind of thoracic aorta covered bracket |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110157454.6A CN102824237B (en) | 2011-06-13 | 2011-06-13 | A kind of thoracic aorta covered bracket |
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| Publication Number | Publication Date |
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| CN102824237A CN102824237A (en) | 2012-12-19 |
| CN102824237B true CN102824237B (en) | 2015-12-09 |
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| CN201110157454.6A Active CN102824237B (en) | 2011-06-13 | 2011-06-13 | A kind of thoracic aorta covered bracket |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103230310B (en) * | 2013-04-19 | 2015-07-15 | 湖南埃普特医疗器械有限公司 | Thoracic aortic aneurysm coated stent and thoracic aortic aneurysm minimally invasive treatment system |
| CN104287871B (en) * | 2014-10-24 | 2017-03-22 | 黄连军 | Aortic dissection aneurysm covered stent |
| CN105030373A (en) * | 2015-09-07 | 2015-11-11 | 湖南埃普特医疗器械有限公司 | Aorta covered stent |
| CN109498210B (en) * | 2018-11-08 | 2021-01-26 | 深圳市先健畅通医疗有限公司 | Lumen stent |
| CN110680578A (en) * | 2019-10-29 | 2020-01-14 | 北京理工大学 | Split combined intracavity repair instrument |
| CN113081386B (en) * | 2019-12-23 | 2023-09-19 | 先健科技(深圳)有限公司 | covered stent |
| WO2022227283A1 (en) * | 2021-04-30 | 2022-11-03 | 光华临港工程应用技术研发(上海)有限公司 | Aortic covered stent |
| CN113331992B (en) * | 2021-04-30 | 2023-12-26 | 光华临港工程应用技术研发(上海)有限公司 | Aortic tectorial membrane support |
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| CN1545400A (en) * | 2002-03-28 | 2004-11-10 | ��ѧҽѧ������ϵ�ɷ�����˾ | Stent |
| CN2675083Y (en) * | 2004-01-06 | 2005-02-02 | 微创医疗器械(上海)有限公司 | Stent graft for |
| CN202105050U (en) * | 2011-06-13 | 2012-01-11 | 北京华脉泰科医疗器械有限公司 | Thoracic aorta covered bracket |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7204848B1 (en) * | 1995-03-01 | 2007-04-17 | Boston Scientific Scimed, Inc. | Longitudinally flexible expandable stent |
| US8083791B2 (en) * | 2003-04-14 | 2011-12-27 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
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2011
- 2011-06-13 CN CN201110157454.6A patent/CN102824237B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1545400A (en) * | 2002-03-28 | 2004-11-10 | ��ѧҽѧ������ϵ�ɷ�����˾ | Stent |
| CN2675083Y (en) * | 2004-01-06 | 2005-02-02 | 微创医疗器械(上海)有限公司 | Stent graft for |
| CN202105050U (en) * | 2011-06-13 | 2012-01-11 | 北京华脉泰科医疗器械有限公司 | Thoracic aorta covered bracket |
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Denomination of invention: A stent covered with thoracic aorta Effective date of registration: 20200925 Granted publication date: 20151209 Pledgee: Beijing finance Company limited by guarantee Pledgor: BEIJING PERCUTEK THERAPEUTICS Co.,Ltd. Registration number: Y2020990001167 |
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Address after: Room 6201, floor 2, building 1, No. 27, Yongwang Road, Daxing biomedical industry base, Zhongguancun Science Park, Daxing District, Beijing 100076 Patentee after: Beijing Huamai Taike Medical Instrument Co.,Ltd. Address before: 102600 No. 27, Yongwang Road, Daxing biomedical industry base, Zhongguancun Science Park, Daxing District, Beijing Patentee before: BEIJING PERCUTEK THERAPEUTICS Co.,Ltd. |
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Date of cancellation: 20210908 Granted publication date: 20151209 Pledgee: Beijing finance Company limited by guarantee Pledgor: BEIJING PERCUTEK THERAPEUTICS Co.,Ltd. Registration number: Y2020990001167 |