CN103550328B - A kind of medicament for the treatment of postpartum milk secretion obstacle - Google Patents
A kind of medicament for the treatment of postpartum milk secretion obstacle Download PDFInfo
- Publication number
- CN103550328B CN103550328B CN201310529006.3A CN201310529006A CN103550328B CN 103550328 B CN103550328 B CN 103550328B CN 201310529006 A CN201310529006 A CN 201310529006A CN 103550328 B CN103550328 B CN 103550328B
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- grams
- herba
- medicament
- milk secretion
- postpartum milk
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- 239000003814 drug Substances 0.000 title claims abstract description 25
- 239000008267 milk Substances 0.000 title claims abstract description 19
- 210000004080 milk Anatomy 0.000 title claims abstract description 19
- 235000013336 milk Nutrition 0.000 title claims abstract description 19
- 230000028327 secretion Effects 0.000 title claims abstract description 15
- 229940079593 drug Drugs 0.000 claims abstract description 7
- 241001148484 Coniogramme japonica Species 0.000 claims abstract description 6
- 241001659736 Vicia unijuga Species 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 3
- 241000218176 Corydalis Species 0.000 claims description 2
- 239000000706 filtrate Substances 0.000 claims description 2
- 238000007789 sealing Methods 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 239000003643 water by type Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 5
- 240000005175 Turpinia pomifera Species 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 240000003793 Rhizophora mangle Species 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 description 8
- 238000003745 diagnosis Methods 0.000 description 7
- 208000019395 Lactation disease Diseases 0.000 description 5
- 206010042576 Suppressed lactation Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000001983 lactogenic effect Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 240000002044 Rhizophora apiculata Species 0.000 description 3
- 230000008034 disappearance Effects 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 208000023661 Haematological disease Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 208000018525 Postpartum Hemorrhage Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000037006 agalactosis Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 230000008131 children development Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000006196 drop Substances 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 210000003372 endocrine gland Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000006589 gland dysfunction Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a kind of medicament for the treatment of postpartum milk secretion obstacle, it is made up by weight of following bulk drugs: three branch and leaf 1-10 parts; Herba Potentillae Bifurcae 1-10 part; Cacumen Securinegae Suffruticosae 1-5 part; Coniogramme japonica (Thunb.) Diels 1-5 part; Herba Elsholtziae penduliforare 1-10 part; Herba Wedeliae Prostratae 1-5 part; Vicia unijuga 1-5 part; Rhizoma Panacis Majoris 1-10 part; Turpinia pomifera(Roxb) D O. 1-10 part; Caulis et Folium Brassicae capitatae 1-10 part; Herba Vernoniae Cinereae 1-10 part; Mangrove bark 1-10 part; Medicament of the present invention, with pure traditional Chinese medicine, adopts traditional manufacture method, remains the property of medicine of medicine, clear curative effect, can effectively treat postpartum milk secretion obstacle.
Description
Technical field
The present invention relates to department of obstetrics and gynecology field, specifically, relate to a kind of medicament for the treatment of postpartum milk secretion obstacle.
Background technology
Postpartum milk secretion obstacle refers to agalactosis after parturient childbirth, in age of sucking without lactogenic or breast amount few, can not meet and feed baby's needs, motherland's traditional medicine is referred to as " galactozemia " or " hypogalactia ".Cause the many factors of puerperal hypogalactia and complicated, postpartum hemorrhage is many, development of breast is poor, psychentonia, mammitis etc. all can cause hypogalactia or galactopoiesis not smooth to some extent, galactopoiesis deficiency not only cannot meet feeding infant demand, need to coordinate milk replacer, also easily cause neonate dyspepsia, affect the consequences such as infant development.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of postpartum milk secretion obstacle.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of postpartum milk secretion obstacle, it is made up by weight of following bulk drugs:
Three 1 ~ 10 part, branch and leaf Herba Potentillae Bifurcaes, 1 ~ 10 part of Cacumen Securinegae Suffruticosae 1 ~ 5 part
Coniogramme japonica (Thunb.) Diels 1 ~ 5 part of Herba Elsholtziae penduliforare 1 ~ 10 part of Herba Wedeliae Prostratae 1 ~ 5 part
Vicia unijuga 1 ~ 5 part of Rhizoma Panacis Majoris 1 ~ 10 part of Turpinia pomifera(Roxb) D O. 1 ~ 10 part
Caulis et Folium Brassicae capitatae 1 ~ 10 part of Herba Vernoniae Cinereae 1 ~ 10 part of mangrove bark 1 ~ 10 part.
Preferably, it is made up by weight of following bulk drugs:
Three 8 parts, branch and leaf Herba Potentillae Bifurcaes, 7 parts of Cacumen Securinegae Suffruticosaes 2 parts
Coniogramme japonica (Thunb.) Diels 3 parts of Herba Elsholtziae penduliforare 7 parts of Herba Wedeliae Prostrataes 4 parts
Vicia unijuga 2 parts of Rhizoma Panacis Majoris 9 parts of Turpinia pomifera(Roxb) D O.s 3 parts
Caulis et Folium Brassicae capitatae 8 parts of Herba Vernoniae Cinereaes 7 parts of mangrove barks 4 parts.
Preferably, described medicament is tablet, capsule, soft capsule, pill, granule, drop pill or decoction.
Medicament of the present invention, with pure traditional Chinese medicine, adopts traditional manufacture method, remains the property of medicine of medicine, clear curative effect, can effectively treat postpartum milk secretion obstacle.
Accompanying drawing explanation
With reference to " Chinese medicine voluminous dictionary " second edition, being described as follows of the crude drug used in the present invention:
Fig. 1 is the explanation of three branch and leaf;
Fig. 2 is the explanation of Herba Potentillae Bifurcae;
Fig. 3 is the explanation of Cacumen Securinegae Suffruticosae;
Fig. 4 is the explanation of Coniogramme japonica (Thunb.) Diels;
Fig. 5 is the explanation of Herba Elsholtziae penduliforare;
Fig. 6 is the explanation of Herba Wedeliae Prostratae;
Fig. 7 is the explanation of Vicia unijuga;
Fig. 8 is the explanation of Rhizoma Panacis Majoris;
Fig. 9 is the explanation of Turpinia pomifera(Roxb) D O.;
Figure 10 is the explanation of Caulis et Folium Brassicae capitatae;
Figure 11 is the explanation of Herba Vernoniae Cinereae;
Figure 12 is the explanation of mangrove bark.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 decoction of the present invention
Get 80 grams, three branch and leaf, Herba Potentillae Bifurcae 70 grams, Cacumen Securinegae Suffruticosae 20 grams, Coniogramme japonica (Thunb.) Diels 30 grams, Semen Ziziphi Spinosae 70 grams, Herba Wedeliae Prostratae 40 grams, Vicia unijuga 20 grams, Rhizoma Panacis Majoris 90 grams, Rhizoma Zingiberis 30 grams, 80 grams, Radix Glycyrrhizae, Rhizoma Seu Herba Bergeniae 70 grams, Herba Corydalis Bungeanae 40 grams, add 15000 ml waters.Heat 5 hours at 70 DEG C in the container of sealing.Be cooled to room temperature, filter, filtrate is decoction of the present invention.
Experimental example
Postpartum milk secretion obstacle diagnosis standard
Postpartum milk secretion obstacle hypogalactia case diagnosis standard, person's standard, exclusion standard reference literature are formulated (You Zhaoling. gynecology of integrated Chinese and western medicine [M] Beijing: China Traditional Chinese Medicine Publishing House, 2006:355-356; State Administration of Traditional Chinese Medicine. Chinese medical disease Standardization of diagnosis and curative effect [M]. Nanjing: publishing house of Nanjing University, 1994:71).Puerperal breast less or without lactogenic, soft breast, without the swollen sense of lactogenic; Picture of the tongue body of the tongue is light red, white and thin fur; Thin and delicate or the thin string of pulse condition.Feeding infant needs can not be met, be diagnosed as postpartum milk secretion obstacle, enter anthology research.
To the endocrine gland dysfunction person puerpera that clarifies a diagnosis, clarify a diagnosis suffer from hepatorenal disease puerpera, cystic hyperplasia of breast person, puerpera's psychiatric system exception person, inpatient with haematological diseases, neonate take a disease patient, compliance difference person, other do not meet postpartum milk secretion obstacle diagnosis standard person and do not include this research in.
Choose patient 50 example meeting postpartum milk secretion obstacle hypogalactia case diagnosis standard, inclusion criteria, puerpera age (25 ± 6.7) year (20-36 year); Body weight (59 ± 6.3) kg (51-68kg); Parity (1.2 ± 0.56) secondary (1-2 time); The dysgalactia course of disease is puerperal (8.5 ± 3.9) d (3-34d); Hemoglobin Value (106.5 ± 11.31) g/L (92-127) g/L.
Therapeutic scheme
Treatment group: the decoction using preparation in embodiment 1.Take 1 every day, each 100 milliliters.It within 2 weeks, is 1 course for the treatment of.
Criterion of therapeutical effect
Criterion of therapeutical effect is pressed grade III Standard and is judged curative effect.Cure: puerpera's clinical symptom disappearance, galactopoiesis is normal, and milk is sufficient, and breast feeding can meet baby's needs.Effective: puerpera's clinical symptom relief, puerpera's galactopoiesis is normal, and milk amount increases, but breast feeding can not meet baby's needs (can meet more than 1/2 of baby's needs).Invalid: puerpera's clinical symptoms is without improvement, and puerpera's milk slightly increases but not obvious, or without change.Cure, effective case statistics is the effective case for the treatment of.
Therapeutic outcome shows, and cures number of cases, effective number of cases is respectively 38 examples, 12 examples, total effective rate 100%.Clinical observation shows, and after treatment, the sign such as patient's picture of the tongue, pulse condition is normal or improve, clinical symptom disappearance such as poor appetite, fullness and distention in the chest and hypochondrium, depressed emotion or improve obviously, and puerperal breasts filling degree, lactogenic is swollen, and sense obviously changes.
Safety evaluatio
All do not find adverse effect over the course for the treatment of.Puerpera's changes all without exception such as lab testing hematuria routine, hepatic and renal function and blood electrolyte, the no abnormal change of nursing baby in lactation period for puerpera baby.
Claims (1)
1. treat the decoction of postpartum milk secretion obstacle for one kind, it is characterized in that, it is made up by following method of following bulk drugs: get 80 grams, three branch and leaf, Herba Potentillae Bifurcae 70 grams, Cacumen Securinegae Suffruticosae 20 grams, Coniogramme japonica (Thunb.) Diels 30 grams, Semen Ziziphi Spinosae 70 grams, Herba Wedeliae Prostratae 40 grams, Vicia unijuga 20 grams, Rhizoma Panacis Majoris 90 grams, Rhizoma Zingiberis 30 grams, 80 grams, Radix Glycyrrhizae, Rhizoma Seu Herba Bergeniae 70 grams, Herba Corydalis Bungeanae 40 grams, add 15000 ml waters, heat 5 hours at 70 DEG C in the container of sealing, be cooled to room temperature, filter, filtrate is described decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310529006.3A CN103550328B (en) | 2013-11-01 | 2013-11-01 | A kind of medicament for the treatment of postpartum milk secretion obstacle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310529006.3A CN103550328B (en) | 2013-11-01 | 2013-11-01 | A kind of medicament for the treatment of postpartum milk secretion obstacle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103550328A CN103550328A (en) | 2014-02-05 |
| CN103550328B true CN103550328B (en) | 2015-09-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310529006.3A Expired - Fee Related CN103550328B (en) | 2013-11-01 | 2013-11-01 | A kind of medicament for the treatment of postpartum milk secretion obstacle |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370936A (en) * | 2010-08-18 | 2012-03-14 | 广州加原医药科技有限公司 | Traditional Chinese medicinal composition for lactation promotion and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6517861B2 (en) * | 2001-01-22 | 2003-02-11 | Council Of Scientific And Industrial Research | Composition of herbal biscuits for lactating mothers acting as dietary supplement and process for preparation thereof |
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- 2013-11-01 CN CN201310529006.3A patent/CN103550328B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370936A (en) * | 2010-08-18 | 2012-03-14 | 广州加原医药科技有限公司 | Traditional Chinese medicinal composition for lactation promotion and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 产后缺乳辨治体会;闫振喆;《中国民族民间医药》;20091231(第23期);第82页，尤其是第82页左栏第1段，第2.1-2.5节 * |
| 南京中医药大学.三枝叶等.《中药大辞典》.上海科学技术出版社,2006,(第2版),第88页右栏第1行,第1697页左栏倒数第7行,第905页右栏倒数第1-2行,第3205页右栏第4-6行,第3330页右栏第24行,第1560页左栏第8行,第2278页右栏倒数第4-5行,第2475页右栏第1行,第253页左栏第20行,第797页左栏第27行,第1263页左栏第36-38行,第1400页第30-31行. * |
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| CN103550328A (en) | 2014-02-05 |
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| ASS | Succession or assignment of patent right |
Owner name: TAN FEIYANG Free format text: FORMER OWNER: PAN LIANXIANG Effective date: 20150806 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Tan Feiyang Inventor before: Pan Lianxiang |
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| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: PAN LIANXIANG TO: TAN FEIYANG |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20150806 Address after: 272049 painless diagnosis and treatment center, Jining Second People's Hospital,, 107 Hongxing Road, Shandong, Jining, Shandong Applicant after: Tan Feiyang Address before: Supply road 272100 in Shandong province Jining City No. 12 Jining Maternal and Child Health-Care Hospital Applicant before: Pan Lianxiang |
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| C14 | Grant of patent or utility model | ||
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150902 Termination date: 20161101 |