CN103740376B - Containing negative dielectric anisotropy liquid crystal composition and the application thereof of two fluorine bis cyclohexane compound - Google Patents

Abstract

The present invention relates to a liquid crystal composition with negative dielectric anisotropy, more precisely, the present invention relates to a liquid crystal composition with negative dielectric anisotropy containing one or several difluorobicyclohexane structure compounds, and its Application: The composition is mainly used for electro-optic adjustment, especially for FFS display, IPS display and VA display in MVA/PVA/PSVA configuration. The liquid crystal composition provided by the invention has large optical anisotropy and excellent low-temperature miscibility, and good high-temperature and UV stability, and is suitable for fast-response display devices of various display modes; overcomes optical anisotropy Smaller shortcomings, effectively improve the optical anisotropy of the composition, reduce the thickness of the liquid crystal layer, in order to speed up the response speed of the liquid crystal display; its application in the liquid crystal display device can significantly improve the problem of slow response of the device , has huge application prospects and market value.

Description

Negative dielectric anisotropic liquid crystal composition containing difluorobicyclohexane compound and its application

technical field

The invention relates to the field of liquid crystal compositions, in particular to a liquid crystal composition with negative dielectric anisotropy, more precisely, the invention relates to a liquid crystal composition with negative dielectric anisotropy containing one or several difluorobicyclohexane structural compounds Liquid crystal composition and its application; the composition is mainly used for electro-optic adjustment, especially for FFS display, IPS display and VA display with MVA/PVA/PSVA configuration.

Background technique

In 1888, the Austrian botanist Friedrich Reinitzer discovered the first liquid crystal material, cholesterol benzoate (cholesterylbenzoate), which is a liquid crystal, which means that a substance has both the fluidity of a liquid and a certain arrangement characteristic similar to a crystal. M.Born (1916) and K.Lichtennecker (1926) respectively discovered and studied the dielectric anisotropy of liquid crystals. In 1932, W.Kast divided the nematic phase into two categories, positive and negative. In 1927, V.Freedericksz and V.Zolinao discovered that the nematic liquid crystal was deformed and had a voltage threshold (Freederichsz transition) under the action of an electric field (or magnetic field). This finding provides a basis for the production of liquid crystal displays. Utilizing the electro-optic effect of liquid crystals, British scientists manufactured the first liquid crystal display, or LCD display, in the last century. Compared with the traditional CRT, LCD is not only small in size, thin in thickness, light in weight, low in energy consumption, low in working voltage, but also has no radiation, no flicker and can directly match with CMOS integrated circuits. Due to its many advantages, LCD has entered the desktop application field since 1998. In recent decades, especially the rapid development of information technology and people's continuous pursuit of information display methods in the past ten years, liquid crystal display has achieved the most rapid development. Today, liquid crystal displays are being displayed in front of people in a variety of forms, and many of its products are becoming fashionable pursuits and popular commodities in shopping malls due to their excellent characteristics.

According to the arrangement of liquid crystal molecules, liquid crystal displays are often divided into: narrow viewing angle TN (Twisted Nematic), STN (Super Twisted Nematic), DSTN (Doublelayer Super Twisted Nematic), etc. The liquid crystal compositions used in these narrow viewing angle liquid crystal displays are dielectric positive sexual. Wide viewing angles include IPS (In-Plane Switching), VA (Vertical Alignment), FFS (Fringe Filed Switching), etc. For liquid crystal displays with wide viewing angles, most of the liquid crystal media used are negative dielectric anisotropy, and IPS can use negative dielectric anisotropy. As the liquid crystal composition with dielectric anisotropy, a liquid crystal composition with positive dielectric anisotropy can also be used. From the perspective of the driving method of the LCD panel, the most common one is the TFT (ThinFilmTransistor) type driver, which can achieve a finer display effect than the previous passive driver. At present, most LCD monitors, LCD TVs and some mobile phones are driven by TFT. LCD monitors mostly use TN mode with narrow viewing angles, and LCD TVs mostly use VA and IPS modes with wide viewing angles. They are commonly called TFT-LCD.

The liquid crystal display provided by the prior art has the disadvantage of slow response speed. The response speed of the liquid crystal display is mainly limited by the thickness of the liquid crystal layer and the rotational viscosity of the liquid crystal. Reducing the thickness of the liquid crystal layer can effectively speed up the response speed of the liquid crystal display, which needs to be improved. Optical anisotropy of liquid crystal compositions.

The LCD response speed is determined by the following formula:

${\mathrm{<span\; class="notranslate">\; \&tau;</span>}}_{\mathrm{<span\; class="notranslate">\; off</span>}}<span\; class="notranslate">\; =</span>\frac{{\mathrm{<span\; class="notranslate">\; \&gamma;d</span>}}^{\mathrm{<span\; class="notranslate">\; 2</span>}}}{{\mathrm{<span\; class="notranslate">\; \&pi;</span>}}^{\mathrm{<span\; class="notranslate">\; 2</span>}}{\mathrm{<span\; class="notranslate">\; K</span>}}_{\mathrm{<span\; class="notranslate">\; 33</span>}}}$

Δn*d=constant; γ is the rotational viscosity of the liquid crystal; d is the thickness of the liquid crystal layer; K ₃₃ is the bending elastic constant of the liquid crystal; Δn is the optical anisotropy of the liquid crystal; Δn*d is the optical retardation of the liquid crystal layer.

It can be seen from the above formula that increasing the response speed of the liquid crystal display requires reducing the thickness of the liquid crystal layer and reducing the rotational viscosity of the liquid crystal. If a liquid crystal composition applied to a liquid crystal display is developed to achieve the above purpose, it will certainly have a huge application prospect and economic value.

Contents of the invention

Aiming at the problems existing in the prior art, the object of the present invention is to provide a liquid crystal composition with negative dielectric anisotropy containing a difluorobicyclohexane compound. The liquid crystal composition has low viscosity and large optical anisotropy, and thus has fast response speed, excellent light stability and thermal stability, and is suitable for fast response liquid crystal display devices.

Another object of the present invention is to provide the application of the negative dielectric anisotropy liquid crystal composition containing a difluorobicyclohexane compound in a liquid crystal display device.

In order to achieve the above object, the negative dielectric anisotropy liquid crystal composition containing difluorobicyclohexane compound provided by the present invention comprises the following components in weight percent:

(1) 5% to 50% of compounds represented by general formula IA or/and IB;

(2) 10% to 80% of the compound represented by general formula II;

(3) 0% to 60% of the compound represented by general formula III;

(4) 1% to 20% of the compound represented by general formula IV;

Wherein, the structural formula of the compound represented by the general formula IA, IB, II, III, IV is as follows:

Wherein, R ₁ , R ₂ , R ₃ , R ₅ , R ₇ and R ₈ each independently represent an alkyl group;

R ₄ and R ₆ each independently represent an alkyl or alkoxy group; n=0 or 1.

Further, R ₁ , R ₂ , R ₃ , R ₅ , R ₇ and R ₈ each independently represent a C ₁ -C ₁₂ alkyl group; R ₄ and R ₆ each independently represent a C ₁ -C ₁₂ alkyl group or a C ₁ -C ₁₂ alkoxy group.

Further, R ₁ , R ₂ , R ₃ , R ₅ , R ₇ and R ₈ each independently represent a C ₂ -C ₅ alkyl group; R ₄ represents a C ₁ -C ₅ alkyl group or a C ₂ -C ₅ alkoxy; R ₆ represents C ₂ -C ₅ alkyl or C ₁ -C ₅ alkoxy.

The alkyl and alkoxy groups used in the present invention are preferably linear.

Further, R ₁ and R ₂ may be the same or different, R ₃ and R ₄ may be the same or different, R ₅ and R ₆ may be the same or different, R ₇ and R ₈ may be the same or different.

Wherein, the weight percentage of the compound represented by the general formula III is preferably 10%-60%.

Preferably, the negative dielectric anisotropy liquid crystal composition containing difluorobicyclohexane compound provided by the present invention includes the following components in weight percentage:

(1) 10% to 50% of compounds represented by general formula IA or/and IB;

(2) 10% to 70% of the compound represented by general formula II;

(3) 10% to 60% of the compound represented by general formula III;

(4) 1% to 20% of the compound represented by the general formula IV.

More preferably, the negative dielectric anisotropy liquid crystal composition containing difluorobicyclohexane compound provided by the present invention includes the following components in weight percentage:

(1) 10% to 40% of compounds represented by general formula IA or/and IB;

(2) 10% to 70% of the compound represented by general formula II;

(3) 10% to 60% of the compound represented by general formula III;

(4) 5% to 20% of the compound represented by general formula IV.

Among them, preferably, the compound represented by the general formula IA is one or more of the compounds represented by the formula IA-1 to formula IA-16:

Among them, preferably, the compound represented by the general formula IB is one or more of the compounds represented by the formula IB-1 to formula IB-16:

Wherein, preferably, the compound represented by the general formula II is one or more of the compounds represented by the formula IIA, formula IIB or formula IIC:

Among them, R ₃ is C ₂ -C ₅ alkyl, R ₄ is C ₂ -C ₅ alkoxy (in formula IIA), R4' is C ₂ -C ₅ alkoxy (in formula IIB), R ₄ '' is a C ₁ -C ₅ alkyl group (in formula IIC).

Among them, more preferably, the compound represented by the general formula II is one of the compounds represented by formula IIA-1 to formula IIA-12, formula IIB-1 to formula IIIB-12 or formula IIC-1 to formula IIIC-20 One or more:

Wherein, preferably, the compound represented by the general formula III is one or more of the compounds represented by the formula IIIA or the formula IIIB:

Among them, R ₅ is C ₂ -C ₅ alkyl, R ₆ ' is C ₂ -C ₅ alkyl (in formula IIIA), R ₆ '' is C ₁ -C ₅ alkoxy (in formula IIIB ).

Among them, more preferably, the compound represented by the general formula III is one or more of the compounds represented by formula IIIA-1 to formula IIIA-16 or formula IIIB-1 to formula IIIB-20:

Among them, preferably, the compound represented by the general formula IV is one or more of the compounds represented by formula IVA-1 to formula IVA-16:

The present invention also provides the application of any one of the above-mentioned negative dielectric anisotropy liquid crystal compositions containing difluorobicyclohexane compounds in liquid crystal display devices.

Among them, the application of any one of the above-mentioned negative dielectric anisotropy liquid crystal compositions containing difluorobicyclohexane compound provided by the present invention in liquid crystal display devices, especially in FFS displays, IPS displays or MVA/PVA/PSVA structures type of VA display applications.

Among the components of the negative dielectric anisotropy liquid crystal composition containing difluorobicyclohexane compound of the present invention:

The difluorobicyclohexane compounds represented by the general formula I have certain negative dielectric anisotropy and low viscosity, which were first seen in the JP4669085 patent, but there is a problem of small optical anisotropy;

The 2,3-difluoro compound represented by the general formula II has strong negative dielectric anisotropy, low viscosity, low clearing point of the bicyclic structure, and high clearing point of the tricyclic structure;

The bicyclic structure represented by the general formula III has a low viscosity and has the effect of reducing the viscosity of the system in the mixed crystal;

The tetracyclic terphenyl compound represented by the general formula IV is a non-polar compound with large optical anisotropy and high clearing point, which can effectively improve the clearing point and optical anisotropy of the system.

The present invention mainly adds the compound represented by the general formula I, which can increase the dielectric anisotropy of the system and reduce the viscosity of the system at the same time, so as to improve the response speed of the liquid crystal.

The preparation method of the negative dielectric anisotropy liquid crystal composition containing difluorobicyclohexane compound of the present invention is not particularly limited, and two or more compounds can be mixed by conventional methods for production, such as by mixing different Components are prepared by dissolving each other, wherein the liquid crystal composition is dissolved in a solvent for the compound and mixed, and then the solvent is distilled off under reduced pressure; or the difluorobicyclohexane-containing compound of the present invention The negative dielectric anisotropy liquid crystal composition can be prepared according to conventional methods, such as dissolving the components with a smaller content in the main component with a larger content at a higher temperature, or dissolving each component in an organic Dissolve in a solvent, such as acetone, chloroform or methanol, etc., and then mix the solutions to remove the solvent.

The negative dielectric anisotropy liquid crystal composition containing difluorobicyclohexane compound provided by the present invention has large optical anisotropy, excellent low-temperature mutual solubility, and good high-temperature and UV stability, and is suitable for various displays In the fast response display device of mode; overcome the shortcoming of small optical anisotropy, effectively improve the optical anisotropy of the composition, reduce the thickness of the liquid crystal layer, so as to speed up the response speed of the liquid crystal display; its application in LCD

In the display device, the problem of slow response of the device can be obviously improved, and has great application prospect and market value.

Detailed ways

The following examples are used to illustrate the present invention, but are not intended to limit the protection scope of the present invention.

The preparation of the liquid crystal composition in the examples of the present invention adopts the following method: the preparation of the uniform liquid crystal adopts the thermal dissolution method commonly used in the industry, and first weighs the liquid crystal compound by weight percentage with a balance, wherein there is no specific requirement for the order of weighing and adding, usually Liquid crystal compounds are weighed and mixed in order of melting point from high to low, heated and stirred at 60-100°C to make each component melt evenly, then filtered, rotary evaporated, and finally packaged to obtain the target sample.

Unless otherwise stated, percentages in this context are by weight and all temperatures are given in degrees Celsius. Use the following abbreviations:

△n is the optical anisotropy (20°C, 589nm); Δε is the dielectric anisotropy (25°C, 1000Hz); V ₁₀ is the threshold voltage, which is the characteristic voltage when the relative transmittance changes by 10% (V, 25°C); η is the bulk viscosity (mm ² /s, 20°C); Cp is the clearing point of the liquid crystal composition (°C); τ _off is the off-state response time, which represents the relative transmittance change of the liquid crystal after the voltage is removed 90% time (ms, 25°C); △n*d is the optical retardation of the liquid crystal layer (μm); γ1 is the rotational viscosity of the liquid crystal (mPa.s, 25°C).

In the present invention, the compounds represented by general formulas II, III and IV can be provided by Beijing Bayi Space-Time Liquid Crystal Technology Co., Ltd.

For ease of expression, in the following examples, the group structure in the liquid crystal compound is represented by the code shown in Table 0:

Table 0: Group Structure Codes of Liquid Crystal Compounds

Take the following structure as an example:

The structure is represented by the code listed in Table 1, which is then expressed as 3HH(2F)3;

Another example is the following structure:

The structure is represented by the code listed in Table 1, and it is represented as 3HHFF3;

Another example is the following structure:

The structure is represented by the code listed in Table 1, and it is expressed as 2HBGB3.

Example 1

The liquid crystal compound in the following weight percentages was taken, and the liquid crystal composition was prepared by the above-mentioned preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 1.

Table 1: The weight percent of each component in the liquid crystal composition of Example 1 and the performance parameters of the overall composition

The structural formula number of the component the code Weight percentage (%) Performance parameters parameter value IA-5 2HHFF3 17 Δn 0.095 IIA-2 3HWO2 10 △ε -2.8 IIA-4 5HWO2 8 V ₁₀ 2.50 IIB-1 2HHWO2 4 n 19 IIB-2 3HHWO2 10 Cp 76 IIB-4 5HHWO2 6 τ _off 4.0 IIC-1 2HHW1 9 △n*d 0.32 IIC-2 3HHW1 8 gamma 1 75 IIIA-4 5HB2 6

IIIB-2 3HBO1 6 IIIB-6 3HBO2 6 IVA-13 5HBGB2 5 IVA-10 4HBGB3 5

Example 2

The liquid crystal compound in the following weight percentages was taken, and the liquid crystal composition was prepared by the above-mentioned preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 2.

Table 2: The weight percent of each component in the liquid crystal composition of Example 2 and the performance parameters of the overall composition

The structural formula number of the component the code Weight percentage (%) Performance parameters parameter value IB-5 2HH(2F)3 20 Δn 0.095 IA-6 3HHFF3 20 △ε -2.0 IIB-1 2HHWO2 10 V ₁₀ 3.05 IIIA-4 5HB2 6 n 15 IIIB-2 3HBO1 6 Cp 80 IIIB-6 3HBO2 6 τ _off 3.0 IIIB-7 4HBO2 6 △n*d 0.32 IIIB-8 5HBO2 6 gamma 1 55 IVA-10 4HBGB3 7 IVA-13 5HBGB2 7 IVA-14 5HBGB3 6

Example 3

The following liquid crystal compounds were taken in the following weight percentages, and the liquid crystal composition was prepared by the above-mentioned preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 3.

Table 3: The weight percent of each component in the liquid crystal composition of Example 3 and the performance parameters of the overall composition

The structural formula number of the component the code Weight percentage (%) Performance parameters parameter value IA-5 3HHFF3 10 Δn 0.090

[0105] IIB-1 2HHWO2 10 △ε -1.5 IIB-2 3HHWO2 10 V ₁₀ 3.21 IIB-4 5HHWO2 5 n 15 IIIA-4 5HB2 6 Cp 70 IIIB-2 3HBO1 8 τ _off 3.5 IIIB-3 4HBO1 8 △n*d 0.32 IIIB-4 5HBO1 6 gamma 1 45 IIIB-6 3HBO2 8 IIIB-7 4HBO2 8 IIIB-8 5HBO2 8 IIIB-14 3HBO4 8 IVA-13 5HBGB2 5

Example 4

Take the following liquid crystal compound in the weight percentage, and prepare the liquid crystal composition by the above-mentioned preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 4.

Table 4: The weight percent of each component in the liquid crystal composition of Example 4 and the performance parameters of the overall composition

The structural formula number of the component the code Weight percentage (%) Performance parameters parameter value IA-5 3HHFF3 10 Δn 0.105 IIA-2 3HWO2 10 △ε -4.0 IIA-4 5HWO2 10 V ₁₀ 2.25 IIA-10 3HWO4 10 n 25 IIB-2 3HHWO2 10 Cp 100 IIB-4 5HHWO2 5 τ _off 5.0 IIB-6 3HHWO3 8 △n*d 0.32 IIC-1 2HHW1 9 gamma 1 101 IIC-2 3HHW1 8 IIIB-2 3HBO1 5 IIIB-6 3HBO2 5

IVA-13 5HBGB2 5 IVA-10 4HBGB3 5

Example 5

The following liquid crystal compounds were taken in the following weight percentages, and the liquid crystal composition was prepared by the above-mentioned preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 5.

Table 5: The weight percent of each component in the liquid crystal composition of Example 5 and the performance parameters of the overall composition

The structural formula number of the component the code Weight percentage (%) Performance parameters parameter value IA-5 2HHFF3 20 Δn 0.096 IA-6 3HHFF3 20 △ε -3.5 IA-10 3HHFF4 10 V ₁₀ 2.32 IIA-2 3HWO2 10 n 20 IIA-4 5HWO2 10 Cp 75 IIB-6 3HHWO3 10 τ _off 4.5 IVA-13 5HBGB2 7 △n*d 0.32 IVA-14 5HBGB3 7 gamma 1 90 IVA-10 4HBGB3 6

Example 6

Take the following liquid crystal compound in the weight percentage, and prepare the liquid crystal composition by the above-mentioned preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 6.

Table 6: The weight percent of each component in the liquid crystal composition of Example 6 and the performance parameters of the overall composition

The structural formula number of the component the code Weight percentage (%) Performance parameters parameter value IA-5 2HHFF3 20 Δn 0.100 IB-6 3HH(2F)3 20 △ε -3.7 IIA-10 3HWO4 10 V ₁₀ 2.32 IIA-2 3HWO2 10 n 20 IIA-4 5HWO2 10 Cp 75

IIB-6 3HHWO3 10 τ _off 4.3 IVA-13 5HBGB2 7 △n*d 0.32 IVA-14 5HBGB3 7 gamma 1 98 IVA-10 4HBGB3 6

Comparative example 1

Take the following liquid crystal compound in the weight percentage, and prepare the liquid crystal composition by the above preparation method. The specific proportion and the performance parameters of the obtained liquid crystal composition (not the individual components) are shown in Table 7.

Table 7: The weight percent of each component in the liquid crystal composition of Comparative Example 1 and the performance parameters of the overall composition

components Weight percentage (%) Performance parameters parameter value 3HH2 8 Δn 0.080 3HH5 9 △ε -3.0 2HHW1 9 V ₁₀ 2.45 3HHW1 8 n 20 3HHWO2 12 Cp 68 5HHWO2 11 τ _off 5.0 3HWO2 16 △n*d 0.32 5HWO2 14 gamma 1 82 3HBO1 6 5HB2 7

Among the negative dielectric anisotropy liquid crystal compositions of the present invention, the liquid crystal compositions prepared with the ratios of the components in Examples 1 to 4 have large optical anisotropy and excellent light stability and thermal stability, and at the same time Due to its low viscosity, it is suitable for liquid crystal display devices with fast response.

In Comparative Example 1, the ratio of each component of the negative dielectric anisotropy liquid crystal composition used in the prior art, the liquid crystal composition prepared with this ratio mainly has a small optical anisotropy, resulting in the desired liquid crystal layer The thickness is larger, so the problem of slower response time. Compared with Comparative Example 1, Example 1 has lower viscosity and greater optical anisotropy, so the thickness of the liquid crystal layer of the display is smaller, so the response time is faster than Comparative Example 1.

The negative dielectric anisotropic liquid crystal composition provided by the present invention has low viscosity, high resistivity, large optical anisotropy, and excellent light stability and thermal stability, and can solve the problem of slow response speed of liquid crystal displays. Suitable for liquid crystal display devices with fast response.

Although, the present invention has been described in detail with general description, specific implementation and test above, but on the basis of the present invention, some modifications or improvements can be made to it, which will be obvious to those skilled in the art . Therefore, the modifications or improvements made on the basis of not departing from the spirit of the present invention all belong to the protection scope of the present invention.

Claims (11)

1., containing a negative dielectric anisotropy liquid crystal composition for two fluorine bis cyclohexane compound, be made up of the component of following weight percent:

(1) 10% ~ 50% general formula I A is or/and compound representated by IB;

Compound representated by (2) 10% ~ 70% general formulas II;

Compound representated by (3) 10% ~ 60% general formula III;

Compound representated by (4) 1% ~ 20% general formula I V;

Wherein, the structural formula of the compound representated by described general formula I A, IB, II, III, IV is as follows:

Wherein, described R ₁, R ₂, R ₃, R ₅, R ₇and R ₈represent C independently of one another ₂~ C ₅alkyl; R ₄represent C ₁~ C ₅alkyl or C ₂~ C ₅alkoxyl group; R ₆represent C ₂~ C ₅alkyl or C ₁~ C ₅alkoxyl group, n=0 or 1.

2. liquid-crystal composition according to claim 1, is characterized in that, described R ₁and R ₂identical or different, R ₃and R ₄identical or different, R ₅and R ₆identical or different, R ₇and R ₈identical or different.

3. liquid-crystal composition according to claim 2, is characterized in that, this liquid-crystal composition is made up of the component of following weight per-cent:

(1) 10% ~ 40% general formula I A is or/and compound representated by IB;

Compound representated by (2) 10% ~ 70% general formulas II;

Compound representated by (3) 10% ~ 60% general formula III;

Compound representated by (4) 5% ~ 20% general formula I V.

4. the liquid-crystal composition according to claims 1 to 3 any one, is characterized in that, one or more in the compound representated by formula IA-1 ~ formula IA-16 of the compound representated by described general formula I A:

One or more in compound representated by described general formula I B compound representated by formula IB-1 ~ formula IB-16:

5. the liquid-crystal composition according to claims 1 to 3 any one, is characterized in that, the compound representated by described general formula I I is formula IIA, one or more in compound representated by formula IIB or formula IIC:

Wherein, R ₃for C ₂~ C ₅alkyl, R ₄for C ₂~ C ₅alkoxyl group, R4 ' is C ₂~ C ₅alkoxyl group, R ₄" be C ₁~ C ₅alkyl.

6. the liquid-crystal composition according to claims 1 to 3 any one, is characterized in that, one or more in the compound representated by formula III A or formula III B of the compound representated by described general formula III:

Wherein, R ₅for C ₂~ C ₅alkyl, R ₆' be C ₂~ C ₅alkyl, R ₆" be C ₁~ C ₅alkoxyl group.

7. the liquid-crystal composition according to claims 1 to 3 any one, is characterized in that, one or more in the compound representated by formula IVA-1 ~ formula IVA-16 of the compound representated by described general formula I V:

8. liquid-crystal composition according to claim 5, is characterized in that, one or more in the compound representated by formula IIA-1 ~ formula IIA-12, formula IIB-1 ~ formula IIB-12 or formula IIC-1 ~ formula IIC-20 of the compound representated by described general formula I I:

9. liquid-crystal composition according to claim 6, is characterized in that, one or more in the compound representated by formula III A-1 ~ formula III A-16 or formula III B-1 ~ formula III B-20 of the compound representated by described general formula III:

10. the application of negative dielectric anisotropy liquid crystal composition in liquid crystal indicator containing two fluorine bis cyclohexane compound described in claim 1 ~ 9 any one.

11. application according to claim 10, is characterized in that, described liquid crystal indicator is the VA escope of FFS indicating meter, IPS indicating meter or MVA/PVA/PSVA configuration.