CN103828804A - Complexly-formulated quaternary ammonium salt disinfectant - Google Patents
Complexly-formulated quaternary ammonium salt disinfectant Download PDFInfo
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- CN103828804A CN103828804A CN201410072549.1A CN201410072549A CN103828804A CN 103828804 A CN103828804 A CN 103828804A CN 201410072549 A CN201410072549 A CN 201410072549A CN 103828804 A CN103828804 A CN 103828804A
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- quaternary ammonium
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- 150000003242 quaternary ammonium salts Chemical class 0.000 title claims abstract description 35
- 239000000645 desinfectant Substances 0.000 title abstract description 38
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 3
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 3
- 239000006184 cosolvent Substances 0.000 claims abstract description 3
- 239000003381 stabilizer Substances 0.000 claims abstract description 3
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims description 14
- 150000001875 compounds Chemical class 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 235000019270 ammonium chloride Nutrition 0.000 claims description 7
- CBFCDTFDPHXCNY-UHFFFAOYSA-N octyldodecane Natural products CCCCCCCCCCCCCCCCCCCC CBFCDTFDPHXCNY-UHFFFAOYSA-N 0.000 claims description 7
- 239000000654 additive Substances 0.000 claims description 6
- 230000000996 additive effect Effects 0.000 claims description 6
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 claims description 6
- 229940033663 thimerosal Drugs 0.000 claims description 6
- -1 salt compound Chemical class 0.000 claims description 3
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 239000003002 pH adjusting agent Substances 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims 1
- 239000013522 chelant Substances 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 26
- 230000000694 effects Effects 0.000 abstract description 14
- 244000005700 microbiome Species 0.000 abstract description 10
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 6
- 241000233866 Fungi Species 0.000 abstract description 3
- 241000700605 Viruses Species 0.000 abstract description 3
- 241000193830 Bacillus <bacterium> Species 0.000 abstract description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract description 2
- 241000191967 Staphylococcus aureus Species 0.000 abstract description 2
- 230000006378 damage Effects 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract description 2
- 230000007794 irritation Effects 0.000 abstract description 2
- 239000000575 pesticide Substances 0.000 abstract description 2
- 239000002689 soil Substances 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- RUPBZQFQVRMKDG-UHFFFAOYSA-M Didecyldimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC RUPBZQFQVRMKDG-UHFFFAOYSA-M 0.000 abstract 2
- 229960004670 didecyldimethylammonium chloride Drugs 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241001523956 Parengyodontium album Species 0.000 abstract 1
- 241000235342 Saccharomycetes Species 0.000 abstract 1
- 206010070834 Sensitisation Diseases 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000711 cancerogenic effect Effects 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 230000000366 juvenile effect Effects 0.000 abstract 1
- 239000002075 main ingredient Substances 0.000 abstract 1
- 238000002703 mutagenesis Methods 0.000 abstract 1
- 231100000350 mutagenesis Toxicity 0.000 abstract 1
- NYNKJVPRTLBJNQ-UHFFFAOYSA-N n'-(3-aminopropyl)-n'-dodecylpropane-1,3-diamine Chemical compound CCCCCCCCCCCCN(CCCN)CCCN NYNKJVPRTLBJNQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000008313 sensitization Effects 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 description 17
- 238000000034 method Methods 0.000 description 9
- 239000008213 purified water Substances 0.000 description 5
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- STIAPHVBRDNOAJ-UHFFFAOYSA-N carbamimidoylazanium;carbonate Chemical compound NC(N)=N.NC(N)=N.OC(O)=O STIAPHVBRDNOAJ-UHFFFAOYSA-N 0.000 description 4
- 230000007797 corrosion Effects 0.000 description 3
- 238000005260 corrosion Methods 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- 125000001453 quaternary ammonium group Chemical group 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 238000003912 environmental pollution Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 244000144972 livestock Species 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000005416 organic matter Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- BWLBGMIXKSTLSX-UHFFFAOYSA-N 2-hydroxyisobutyric acid Chemical compound CC(C)(O)C(O)=O BWLBGMIXKSTLSX-UHFFFAOYSA-N 0.000 description 1
- 229910000975 Carbon steel Inorganic materials 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical class O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical class CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 101710172711 Structural protein Proteins 0.000 description 1
- OALWUEBKKOGWOF-UHFFFAOYSA-M [Cl-].[I+] Chemical group [Cl-].[I+] OALWUEBKKOGWOF-UHFFFAOYSA-M 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 231100000460 acute oral toxicity Toxicity 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- QJSIEZCCOGZFLT-BTVCFUMJSA-N butanedioic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC(=O)CCC(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O QJSIEZCCOGZFLT-BTVCFUMJSA-N 0.000 description 1
- 239000010962 carbon steel Substances 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000001086 cytosolic effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 239000008233 hard water Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 150000002730 mercury Chemical class 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000010539 reproductive behavior Effects 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a complexly-formulated quaternary ammonium salt disinfectant. The complexly-formulated quaternary ammonium salt disinfectant is prepared from the following ingredients: N,N-bis(3-amino propyl) dodecylamine used as a main ingredient of the antibacterial agent, didecyldimethylammonium chloride (DDDMAC) with strong antibacterial effect, a synergist, a stabilizing agent, a pH regulator, an antioxidant and a cosolvent; the complexly-formulated quaternary ammonium salt disinfectant is mainly characterized in that novel, stable and high-efficiency quaternary ammonium salt is adopted for achieving disinfectant and antibacterial effects; the complexly-formulated quaternary ammonium salt disinfectant can rapidly kill fungus, saccharomycetes, colon bacillus, pseudomonas aeruginosa, Staphylococcus aureus, Tritirachium album, virus and other microorganisms in a highly-efficiency broad-spectrum manner; the complexly-formulated quaternary ammonium salt disinfectant has the advantages of having wide application range, good disinfection effect, no toxic action, no carcinogenic effect, no sensitization, no mutagenesis, no pesticide resistance formation, no irritation, no corrosivity, no foreign smell and no flammability, having capability of effectively killing harmful microorganisms such as bacteria, viruses and fungus, which are harm to higher organisms in all life stages (including a reproduction period and a juvenile stage), having capability of natural degradation in soil, no secondary pollution, having stable performance, having less possibility of losing efficacy due to light, heat and the like, and having economical and practical effects, can achieve rapid high-efficiency broad-spectrum disinfection effect compared with similar products, and has low price.
Description
Technical field
The present invention relates to a kind of compound prescription quaternary ammonium salt disinfectant of a kind of disinfectant, particularly environment-friendly high-efficiency.
Background technology
At present, in market, common disinfectant major part is chloride (iodine) class, Peracetic acid class, hydroperoxide kind, formalin class, penta and traditional disinfectants such as aldehydes, chlorohexidene class, phenols, mercury class, bases, acids are mainly used in: government utility sterilization, daily life sterilization, health care sterilization, food and drink and the sterilization of medicine industry, livestock breeding industry sterilization, Water Disinfection.But be widely used traditional disinfectant and show gradually the shortcomings that is difficult to elimination: on the one hand, tradition disinfectant needs relatively high valid density just can reach Disinfection Effect, and mostly there is penetrating odor, the article that are sterilized are had to corrosivity, even produce noxious material harm human and livestock health.On the other hand: traditional disinfectant is difficult for degraded, flow in water system and soil and can cause secondary environmental pollution.Moreover the complicate fabrication process of some disinfectant, is difficult for storing and transport, indirectly causes high cost.Therefore, these defects of traditional disinfectant have limited their ranges of application in modern society greatly, are abandoned just matter of time by fast-developing society.
In the face of the active demand of social each field to novel environment friendly high-efficiency sterile products, researchers have developed various types of new products.Wherein quaternary ammonium disinfectant is exactly one of disinfectant being sent to very big hope.The sterilization mechanism of generally acknowledging at present quaternary ammonium salt disinfectant liquid is: quaternary ammonium salt carries positive charge in the aqueous solution, can be adsorbed on electronegative microorganism surface and form micelle, and progressively infiltrate cytoplasmic lipoid layer and protein layer.This ability of quaternary ammonium salt can change after birth permeability, and cellular content is exosmosed, and finally causes microbial death.Quaternary ammonium salt solidifies again the intracellular protein of energy simultaneously, makes enzyme (as the enzyme of dehydrogenase oxidoreductase enzyme and decomposition glucose succinate acetonate) and structural proteins sex change, and the metabolism of destroy microorganisms, thoroughly kills microorganism.In addition, in two long chain quaternary structures, with 1 hydrophilic radical and 2 hydrophobic groupings, there is the capillary ability of reasonable water-soluble and good reduction, also there is the adverse effect of opposing anion active agent, hard water, albumen organic matter etc.In addition quaternary ammonium salt solution is not only water-soluble fabulous but also be subject to water quality impact less, and its foam is also little.
In addition, the film that QAS polymer forms can wrap up microorganism closely, and then suppresses it and copy the reproductive behaviors such as division, so quaternary ammonium salt disinfectant has sterilization fungistatic effect.Sterilization process that it should be noted that this bactericide produces rapidly and not any harmful substance, does not affect other any irrelevant compositions in sterilization environment, is therefore sterilized dose of safety non-toxic.And the sharpest edges of relative other the general disinfectants of quaternary ammonium salt disinfectant are form and kinds that its sterilization mechanism does not rely on microorganism, in other words, the mutation of microorganism and variation do not affect the performance of quaternary ammonium salt bactericide effect, it can not make microorganisms pesticide resistance, even if therefore continue long-term use, drug effect also at all can not reduce.
Since Jocobs in 1915, synthetic concurrent current season, ammonium salt had Action of Surfactant first, and after having certain Disinfection Effect, quaternary ammonium disinfectant has been obtained significant progress.Now common quaternary ammonium disinfectant remain problem be: 1. bactericidal effect is subject to organic substance influence larger; 2. incompatibility is more; 3. price is more expensive; 4. poor to part microorganism effect, particularly for some fungi and virus.
Technical method of the present invention is by literature survey and experimental study, finds that specific strand quaternary ammonium salt and double-chain quaternary ammonium salt, by adopting unique proportioning combination, have powerful sterilization effect.Simultaneously by adding the auxiliary element of specific proportions, can improve effect and the penetration power of quaternary ammonium salt active ingredient in conjunction with cell membrane, and then widen disinfection and compose, improve fungicidal effectiveness, shorten disinfecting time, and do not produce biomolecule resistant, therefore Disinfection Effect obviously improves than current quaternary ammonium salt disinfectant of the same type.This disinfectant can be killed 99% staphylococcus aureus, hay bacillus and Pseudomonas aeruginosa for 30 seconds.Meanwhile, this technology adopts the more active ingredient of low toxic and environment-friendly, less to eco-environmental impact, do not produce secondary environmental pollution, and price is cheaper.In addition, this technical method, by optimizing additive formulations, has improved stability and the dissolubility of disinfectant active ingredient, is not subject to extraneous unfavorable factor as the impact such as organic matter, PH, has also reduced some incompatibility of quaternary ammonium salt disinfectant simultaneously.This technology has improved the concentration of mother liquor by suitable compound method, facilitated preparation to use, and indirectly reduced cost of transportation.
Summary of the invention
Main purpose of the present invention is to solve that existing quaternary ammonium salt disinfectant Disinfection Effect is undesirable, and active ingredient is unstable, is subject to the defects such as such environmental effects, provides a kind of effective and safe more stable quaternary ammonium salt disinfectant compound method.
The technical characterictic that the invention provides the stable disinfectant of a kind of more highly effective and safe is: a kind of compound prescription quaternary ammonium salt thimerosal, it is characterized in that its component and the w/v N that is 10-30%, N-bis-(3-aminopropyl) lauryl amine, the didecyl Dimethy ammonium chloride (DDDMAC) of 5-20%, the additive of 5-15% (comprises synergist, stabilizing agent, pH adjusting agent, antioxidant and cosolvent), all the other are all purified water.Described additive is one or more metal salt compounds and organic high molecular compound.
The feature of the disinfectant of manufacture of the present invention is:
1. " double-chain quaternary ammonium salt " active factors bacteriocidal concentration is low, generally uses 0.01-0.1%;
2. sterilization speed is fast, can kill 99% pathogenic microorganism within 30 seconds.Bactericidal effect, along with the raising of sterilization component concentration and sterilizing time extend and strengthen, is killed logarithm value >=5.00 simultaneously;
3. through acute oral toxicity test and irritation test and acute ocular thorn property result of the test: skin irritation index≤0.5, proves that this compound prescription disinfectant has nontoxic, non-stimulated;
4. LD
50>5000mg/kg body weight, proves that this compound prescription disinfectant is nontoxic
5. through carbon steel, copper, the corrosion test of stainless steel and aluminium, result is corrosion rate R(mm/a) <0.0100, show no corrosion effect;
6. easy to use, stable performance, is difficult for decomposing, fast light, heat-resisting, resistance to storage, and effectively the sterilization duration is long;
7. the structure of main sterilization component is that saturated fatty acid connects, and biological degradability is good, to environment (waters) non-secondary pollution.
To sum up, this invention has overcome that the Disinfection Effect of existing quaternary ammonium salt disinfectant is not good, incompatibility is more, stable effective ingredients is poor and be subject to the deficiencies such as such environmental effects, and therefore this compound prescription quaternary ammonium salt disinfectant can be widely used in the sterilization of industry, agricultural, hospital, family, forestry, oil field, various water circulation system and public environment health.
compound method and step:
Prepare the method for above-mentioned compound prescription quaternary ammonium salt disinfectant, comprise the following steps: progressively add appropriate additive and dissolve according to formula, by proportionally middle dissolving of effective disinfection composition quaternary ammonium salt, then add appropriate pure water constant volume, stir, be the slightly liquid of thickness of clear, packaging is dispatched from the factory.
Can observe with the following Examples implementation procedure of the present invention, these embodiment are only illustrative, can not be construed as limiting the present invention.
Embodiment mono-:
Formula:
| N, N-bis-(3-aminopropyl) lauryl amine | 20ml |
| Didecyl Dimethy ammonium chloride | 10ml |
| Na 2CO 3 | 0.25g |
| Guanidine carbonate | 7g |
| EDTA | 5g |
| Pure water | Add to 100ml |
Step:
1. get purified water 50ml, progressively add Na
2cO
3, guanidine carbonate and EDTA, to be dissolved rear for subsequent use;
2. add N, N-bis-(3-aminopropyl) lauryl amine, is stirred to whole dissolvings;
3. add didecyl Dimethy ammonium chloride, be stirred to whole dissolvings;
4. measure pH value
5. add appropriate amount of purified water to be settled to 100ml.
Embodiment bis-:
Formula:
| N, N-bis-(3-aminopropyl) lauryl amine | 18ml |
| Didecyl Dimethy ammonium chloride | 9ml |
| Na 2CO 3 | 0.25g |
| Guanidine carbonate | 7g |
| EDTA | 5g |
| Pure water | Add to 100ml |
Step:
1. get purified water 50ml, progressively add Na
2cO
3, guanidine carbonate and EDTA, to be dissolved rear for subsequent use;
2. add N, N-bis-(3-aminopropyl) lauryl amine, is stirred to whole dissolvings;
3. add didecyl Dimethy ammonium chloride, be stirred to whole dissolvings;
4. measure pH value
5. add appropriate amount of purified water to be settled to 100ml.
Claims (5)
1. a compound prescription quaternary ammonium salt thimerosal, it is characterized in that its component and the w/v N that is 10-30%, N-bis-(3-aminopropyl) lauryl amine, the didecyl Dimethy ammonium chloride (DDDMAC) of 5-20%, the additive of 5-15% (comprises synergist, stabilizing agent, pH adjusting agent, antioxidant and cosolvent), all the other are distilled water.
2. a compound prescription quaternary ammonium salt thimerosal, is characterized in that additive is metal salt compound or organic high molecular compound.
3. a kind of quaternary ammonium salt thimerosal according to claim 1, is characterized in that: the N that w/v is 10-30%, N-bis-(3-aminopropyl) lauryl amine.
4. a kind of quaternary ammonium salt thimerosal according to claim 1, is characterized in that: the didecyl Dimethy ammonium chloride (DDDMAC) that w/v is 5-20%.
5. according to a kind of quaternary ammonium salt thimerosal described in claim 1 and 2, described slaine is mainly silicate, carbonate and metallo-chelate.
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| CN201410072549.1A CN103828804A (en) | 2014-03-03 | 2014-03-03 | Complexly-formulated quaternary ammonium salt disinfectant |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410072549.1A CN103828804A (en) | 2014-03-03 | 2014-03-03 | Complexly-formulated quaternary ammonium salt disinfectant |
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|---|---|
| CN103828804A true CN103828804A (en) | 2014-06-04 |
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ID=50792957
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|---|---|---|---|
| CN201410072549.1A Pending CN103828804A (en) | 2014-03-03 | 2014-03-03 | Complexly-formulated quaternary ammonium salt disinfectant |
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| CN104488862A (en) * | 2015-01-13 | 2015-04-08 | 北京中海诚达科贸有限公司 | Anion-cation surface-active agent compounded disinfectant technology |
| CN106567278A (en) * | 2016-11-09 | 2017-04-19 | 青岛如相化工科技有限公司 | Onsite & online preparation and synthesis of bactericide |
| CN108566947A (en) * | 2017-03-10 | 2018-09-25 | 洛阳惠中兽药有限公司 | A kind of foam disinfectant auxiliary agent, preparation method and foamaseptic prepared therefrom |
| CN110113943A (en) * | 2016-12-22 | 2019-08-09 | 陶氏环球技术有限责任公司 | The synergistic combination of double-(3- aminopropyl) dodecyl amine and sorbic acid |
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| CN114532352A (en) * | 2022-01-26 | 2022-05-27 | 苏州百灵威超精细材料有限公司 | Compound quaternary ammonium salt long-acting disinfectant and preparation method and application thereof |
| CN114767560A (en) * | 2022-05-20 | 2022-07-22 | 常州瑞昊环保科技有限公司 | Antibacterial composition and application thereof |
| CN115152758A (en) * | 2022-08-02 | 2022-10-11 | 北京洛娃日化有限公司 | Disinfectant for shoes and socks and preparation method thereof |
| CN116200179A (en) * | 2023-02-17 | 2023-06-02 | 广东海洋大学 | Surfactant preparation for reducing corrosion of sulfate reducing bacteria in petroleum exploitation and pipeline transportation and preparation method thereof |
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|---|---|---|---|---|
| DE19526481A1 (en) * | 1995-07-20 | 1997-01-23 | Merz & Co Gmbh & Co | Tuberculocidal powdered disinfectant compsn. for instruments |
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| DE102006051559A1 (en) * | 2006-11-02 | 2008-05-08 | Merz Pharma Gmbh & Co. Kgaa | Detergents and disinfectants with improved destroying effect for hygienic medical applications |
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