CN114668958A - A drug balloon catheter with blood blocking and plaque cutting functions - Google Patents

Abstract

The invention belongs to the technical field of cardiovascular interventional therapy, in particular to a drug balloon catheter with blood blocking and plaque cutting functions. In the present invention, the rear stent balloon unit, the front blocking balloon unit, the guide wire for traction and the combined three-tube unit are arranged on the three-lumen tube unit, so as to achieve blood blocking and plaque reduction before the drug balloon is applied to the inner wall of the blood vessel. The purpose of block cutting. The present invention has the following advantages: firstly, in the three-lumen tube unit, one chamber is used for installing the guide wire, another chamber is used for the stent balloon unit after inflation, and the last chamber is used for blocking the balloon unit before inflation, ensuring three These actions are independent of each other and do not affect each other; second, the surface of the rear stent balloon unit is coated with drugs, which are always closed before and during insertion of the drug balloon catheter to reduce the scouring and loss of drugs by blood.

Description

A drug balloon catheter with blood blocking and plaque cutting functions

technical field

The invention belongs to the technical field of cardiovascular interventional therapy, in particular to a drug balloon catheter with blood blocking and plaque cutting functions.

Background technique

Vascular diseases, such as vascular calcification, atherosclerosis, etc., generally include the narrowing of the inner diameter of the blood vessels. At this time, vascular interventional surgery is required to clear the originally blocked blood vessels. With the rapid development of neuroimaging, catheter technology and materials, computers and other sciences, vascular interventional surgery has also experienced multiple generations of gradually optimized technologies.

1. Balloon catheter intervention

A balloon catheter is a commonly used tool for endovascular angioplasty. It uses a guide wire and a guiding catheter to deliver a balloon into the stenosis of the blood vessel, inflate the balloon with pressure, break the plaque, and finally dilate the blood vessel and improve blood flow. . However, in 30-40% of patients after surgery, the blood vessels become narrowed again due to many reasons such as vascular endothelial injury, excessive proliferation of smooth muscle cells, and lack of support for the dilated blood vessels.

2. Vascular stent treatment

This technique is to install a mesh-shaped metal stent on the outside of the above-mentioned balloon, still through a balloon catheter, to deliver the stent to the lesion site, and then to permanently embed the stent into the coronary intima of the patient after expanding the balloon. However, in this way, the blood vessels of 10-20% of the patients still have smooth muscle hyperplasia due to the immune response of the human body, and finally the blood vessels after stent expansion will be narrowed again.

Since the stent is permanently embedded in the patient's coronary intima, it is impossible to remove the implanted stent and re-stent it.

3. Drug-loaded stent technology

In order to solve the problem of vascular restenosis caused by stent implantation, drug-loaded stents have rapidly become the main means of cardiovascular stent implantation treatment technology in recent years. Due to the coating of a layer of drugs that inhibit smooth muscle growth on the surface of the metal stent, the patient's postoperative vascular restenosis rate can be reduced to less than 5%.

However, compared with ordinary bare stents without drug-loading, drug-loaded stents are very expensive, and the polymer material on the drug-loaded coating may cause thrombosis in some patients, eventually leading to serious adverse reactions.

4. Drug Balloon Catheter Technology

Therefore, further, the balloon catheter with drug coating came into being. Compared with drug-loaded stent, it has drugs that inhibit the growth of smooth muscle, but it does not need coating polymer material, so it will not cause serious thrombosis and other serious problems. Adverse reactions.

This kind of balloon catheter is coated with a therapeutic drug on the outer surface of the balloon. When the balloon reaches the diseased part of the blood vessel, the balloon is expanded to make the drug coating on the surface contact the inner wall of the blood vessel, and the drug is released and released. Act on the lesion site, so as to achieve the purpose of treatment and prevention of intravascular restenosis. In this way, even if the patient's blood vessels will be narrowed and blocked again, a second treatment can be performed.

For example, the Chinese utility model patent with the patent announcement number of CN205831969U and the announcement date of 2016.12.28 discloses an inner stent drug balloon for interventional therapy, including a catheter group, a self-expanding stent and a balloon; A tube and an inner tube; the stent includes a main body, a proximal end and a distal end; the inner tube penetrates into the stent from the proximal end and extends to be confluent and fixed with the distal end, and the proximal end is slidably sleeved on the outer wall of the inner tube; the stent It is located in the balloon, one end of the balloon is fixedly connected to the outer tube, the inside of the balloon and the inside of the outer tube are connected with each other, and the other end is fixedly connected with the distal end of the bracket and the inner tube.

The stent drug balloon in this utility model patent can achieve the effect of the most basic drug balloon catheter technology, but in the process of use, there are still at least the following two problems:

First, when the balloon enters the blood vessel, the drug on the balloon will rub against the blood vessel wall, and then fall off in large quantities;

Second, when the balloon enters the blood vessel, the drug on the balloon will be flushed by the blood, which also causes a large amount of drug loss and cannot reach the lesion.

Therefore, in summary, there is an urgent need for a new type of drug balloon catheter device with improved structure to ensure that the drugs on the balloon reach the vascular lesions as much as possible.

SUMMARY OF THE INVENTION

The present invention provides a drug balloon catheter with blood blocking and plaque cutting functions, which can be achieved by arranging a rear stent balloon unit, a front blocking balloon unit, a guide wire for traction and a combined three-lumen tube unit on a three-lumen tube unit. The tube unit is used to achieve the purpose of blood blocking and plaque cutting before the drug balloon is applied to the inner wall of the blood vessel.

The technical solution adopted by the present invention to solve the above problems is: a drug balloon catheter with blood blocking and plaque cutting functions, comprising a three-lumen tube unit, which is arranged on the three-lumen tube unit and is used for vascular lesions The rear stent balloon unit for plaque cutting and drug application operations is arranged on the three-lumen tube unit, and the front blocking balloon unit for blocking blood before the rear stent balloon unit is deployed is arranged on the A guide wire for traction in the three-lumen tube unit, and a guide wire disposed at the insertion rear end of the three-lumen tube unit, and used for performing pressure filling and decompression operations on the rear stent balloon unit and the front blocking balloon unit, The traction guide wire is a combined three-tube unit for inserting and installing operations.

A further preferred technical solution is that: the three-lumen tube unit includes a tube wire, and a guide wire through hole arranged in the tube wire is arranged in the tube wire and used to inflate the rear stent balloon unit. The treatment hole for pressure relief operation is arranged in the tube wire, and the sealing hole for performing the pressure filling and relief operation on the front blocking balloon unit is arranged on the rear end hole of the treatment hole , and a front-end hole arranged on the plugging channel.

A further preferred technical solution is that: the rear stent balloon unit includes a non-compliant balloon sleeved on the tubing wire, covering the rear end hole, and closed at both ends, and disposed on the non-compliant balloon. The drug layer on the outer surface is sleeved on the outside of the non-compliant balloon, and the two ends are respectively fixed to the metal stent of the tube wire, and is arranged on the tube wire and is located at two ends of the rear end hole respectively. Two drug labeling rings at side locations.

A further preferred technical solution is that: the front blocking balloon unit includes a compliant balloon sleeved on the tube wire, covering the front end hole, and closed at both ends, and a sealing member disposed on the tube wire. Plug the marker ring.

A further preferred technical solution is that: the three-lumen tube unit further includes an inner tube disposed in the through hole of the guide wire and used for installing the drug marking ring and the blocking marking ring.

A further preferred technical solution is that: the combined three-tube unit includes a through hole for butt-jointing the guide wire, and is used for inserting the middle tube body of the guide wire for traction, is arranged on the middle tube body, and is connected to the treatment The first side pipe of the hole is used, and the second side pipe is arranged on the middle pipe body and connected to the hole for blocking.

A further preferred technical solution is that: the three-lumen tube unit further comprises an insertion tip set on the tube wire, and a middle guide wire hole set in the insertion tip.

A further preferred technical solution is that: the diameter of the middle guide wire hole is smaller than that of the guide wire through hole.

A further preferred technical solution is that: the front occlusion balloon unit further includes two assembling pressure rings respectively disposed at both ends of the compliant balloon and used to embed the tubing wire.

A further preferred technical solution is that a three-cavity connecting hose is further arranged between the middle pipe body and the pipe wire.

The present invention has the following advantages.

First, in the three-lumen tube unit, one lumen is used to install the guide wire, another lumen is used to inflate the stent balloon unit, and the last lumen is used to block the balloon unit before expansion, so as to ensure that the three actions are independent of each other. Does not affect.

Second, the surface of the rear stent balloon unit is coated with a drug, which is always closed before and during insertion of the drug balloon catheter, thereby reducing the scouring and loss of the drug by the blood.

Third, before the rear stent balloon unit is opened, the front blocking balloon unit is opened first to block blood upstream, so as to ensure that the drugs on the rear stent balloon unit are transferred to the lesion as much as possible and improve the utilization of drugs. Rate.

Fourth, the rear stent balloon unit includes a common stent, which can embed and cut the plaque when it is expanded and opened, so as to ensure that the drug takes effect faster and has a better effect.

Fifth, both the rear stent balloon unit and the front blocking balloon unit have a marking structure, which ensures that the insertion action of the drug balloon catheter is more accurate, and the rear stent balloon unit is sufficiently aligned with the lesion site.

Sixth, the rear stent balloon unit and the front blocking balloon unit are convenient for pressure inflation and pressure relief operations, ensuring that the drug balloon catheter is easily withdrawn.

Seventh, the specific structure of the entire drug balloon catheter is sufficiently stable, the operation is relatively comfortable and convenient, and it is suitable for various cardiovascular diseases.

Description of drawings

FIG. 1 is a schematic structural diagram of the present invention.

FIG. 2 is a schematic diagram of the position structure of the three-lumen tube unit in the present invention.

FIG. 3 is a schematic diagram of the position structure of the inner tube in the present invention.

FIG. 4 is a schematic diagram of the positional structure of the combined three-pipe unit in the present invention.

FIG. 5 is a schematic diagram of the installation position of the assembling pressure ring in the present invention.

FIG. 6 is a schematic diagram of the position and structure of the three-chamber connecting hose in the present invention.

In the drawings, the components represented by the symbols are as follows: three-lumen tube unit 1, rear stent balloon unit 2, front blocking balloon unit 3, traction guide wire 4, combined three-tube unit 5, tube wire 101, guide wire Silk through hole 102, treatment hole 103, blocking hole 104, rear end hole 105, front end hole 106, non-compliant balloon 201, metal stent 202, drug marking ring 203, compliant balloon 301, blocking mark Ring 302 , inner tube 107 , middle tube body 501 , first side tube 502 , second side tube 503 , insertion tip 108 , middle guide wire hole 109 , assembly pressing ring 303 , three-lumen connecting hose 6 .

Detailed ways

The following descriptions are only preferred embodiments of the present invention, and do not limit the scope of the present invention.

As shown in the accompanying drawings 1-6, a drug balloon catheter with blood blocking and plaque cutting functions includes a three-lumen tube unit 1, which is arranged on the three-lumen tube unit 1 and is used for vascular lesions. The rear stent balloon unit 2 for plaque cutting and drug smearing operations is arranged on the three-lumen tube unit 1, and the front blocking balloon unit used to block blood before the rear stent balloon unit 2 is deployed 3, the traction guide wire 4 arranged in the three-lumen tube unit 1, and the insertion rear end of the three-lumen tube unit 1, and used for the rear stent balloon unit 2 and the front blocking balloon A combined three-tube unit 5 in which the unit 3 performs pressure filling and decompression operations, and performs insertion and installation operations on the traction guide wire 4 .

In this embodiment, the production method of the drug balloon catheter generally includes the following steps.

First, the three-lumen structure of the three-lumen tube unit 1 is self-contained, and the three-lumen tube needs to be punched first to ensure that the rear stent balloon unit 2 and the front blocking balloon unit 3 can be in the corresponding position. The punching position is expanded by inflation and compressed by low pressure.

Second, dip-coating or ultrasonically spraying drugs on the balloon surface of the rear stent balloon unit 2 .

Third, install the stent of the rear stent balloon unit 2 on the outer ring surface of the three-lumen tube unit 1 by laser welding.

Fourth, the necessary marking structures of the rear stent balloon unit 2 and the front blocking balloon unit 3 are installed to ensure that after the drug balloon catheter enters the blood vessel, its position can be checked and controlled.

Fifth, install the respective balloons of the rear stent balloon unit 2 and the front blocking balloon unit 3 on the outer ring surface of the three-lumen tube unit 1 .

Finally, the combined three-tube unit 5 and the three-lumen tube unit 1 are correspondingly connected, so as to ensure that the basic function of "pressure filling and decompression in two chambers and threading guide wire in one chamber" is effective.

The three-lumen tube unit 1 includes a tube wire 101 , and a guide wire through hole 102 arranged in the tube wire 101 is arranged in the tube wire 101 and used to inflate and discharge the rear stent balloon unit 2 The treatment hole 103 for pressure operation is arranged in the tube wire 101, and the sealing hole 104 for performing the pressure filling and decompression operation of the front sealing balloon unit 3 is arranged on the treatment hole 103 The rear end hole 105 and the front end hole 106 provided on the blocking hole 104 .

In this embodiment, the material of the tube wire 101 can be commonly used medical grade stainless steel or safety resin, the guide wire through hole 102 is in the center of the tube wire 101 , and the treatment hole 103 . The holes 104 for plugging are on both sides of the center of the circle, and the two are set apart as far as possible.

In addition, the guide wire through hole 102 is opened at both ends, and the treatment hole 103 and the plugging hole 104 start from the connecting end of the tube wire 101 and the combined three-tube unit 5, and are opened to an appropriate depth, that is, For example, the opening depth of the treatment hole 103 is 80% of the length of the tube wire 101 , and the opening depth of the blocking hole 104 is 95% of the length of the tube wire 101 .

Finally, the rear end hole 105 is completely covered by the balloon of the rear stent balloon unit 2, and the front end hole 106 is completely covered by the balloon of the front blocking balloon unit 3, so as to ensure that the two balloons are completely closed. Expand and shrink actions are effective and independent of each other.

The rear stent balloon unit 2 includes a non-compliant balloon 201 sleeved on the tube wire 101, covering the rear end hole 105, and closed at both ends, and disposed on the outer surface of the non-compliant balloon 201. The upper drug layer is sleeved on the outside of the non-compliant balloon 201, and the two ends are respectively fixed to the metal stent 202 of the tube wire 101, and are arranged on the tube wire 101, and are respectively located at the rear end Two drug marker rings 203 at positions on either side of the hole 105 .

In this embodiment, the non-compliant balloon 201 refers to that the balloon will not increase after being compressed to a certain pressure, and it is also a commonly used balloon for vascular interventional surgery. The outer ring surface of the pipe wire 101 is laser welded, and its material is PA or Pebax.

In addition, the drug layer is a micro-lens structure, and the drug body is selected from immunosuppressants such as rapamycin and paclitaxel, and the drug layer also includes organic solvents such as isopropanol and acetonitrile. After the non-compliant balloon 201 is coated with the drug layer, it is folded into several flaps by a balloon folding machine and rolled together to ensure that when the drug balloon catheter is added to the blood vessel, the drug will not be washed away by a large amount of blood. fall.

In addition, the material of the metal stent 202 is an existing common nickel-titanium alloy with memory properties, and both ends are welded to the outer ring surface of the pipe wire 101 respectively, and the non-compliant balloon 201 is expanded, so that Expanding the metal stent 202 finally has the function of squeezing and cutting vascular calcified plaque. The squeezing can deform the vascular plaque, increase the surface area, and improve the efficiency of drug application, and the cutting action is an upgrade of the squeezing action.

The front occlusion balloon unit 3 includes a compliant balloon 301 sheathed on the tubing wire 101, covering the front end hole 106 and closed at both ends, and a occlusion mark set on the tubing wire 101 Ring 302.

In this embodiment, the material of the occlusion marking ring 302 is the same as that of the drug marking ring 203, both of which are mainly made of polymer plastic, and Wu, Ba, Bi, etc. are used as X-ray imaging components to ensure the safety of the drug balloon catheter. The insertion speed and depth can be checked and controlled under the guidance of X-ray. The occlusion marking ring 302 and the drug marking ring 203 are both pressed and fixed on the outer ring surface of the tube wire 101 by the existing crimping machine.

In addition, within a certain pressure value range of the compliant balloon 301, as the inflation pressure of the front end hole 106 increases, the inflated volume of the compliant balloon 301 is also larger, ensuring that the drug balloon catheter is in place, that is, the vascular plaque is located at the two sides. When the drug marking rings 203 are in the middle, the compliant balloon 301 can be fully inflated first to block the blood upstream of the blood vessel, so as to prevent the drug layer from being flushed and lost by blood during the deployment process.

Finally, the material of the compliant balloon 301 is latex or silica gel, and both ends thereof are also sealed and fixed on the outer ring surface of the tube wire 101 by means of wire binding and metal ring fixing.

The three-lumen tube unit 1 further includes an inner tube 107 disposed in the guide wire through hole 102 and used for installing the drug marking ring 203 and the occluding marking ring 302 .

In this embodiment, the drug marking ring 203 and the blocking marking ring 302 can be optionally installed in two different ways.

First, it is installed on the outer ring surface of the tube wire 101 and the inner side of the corresponding balloon. The advantage of this method is that the inner tube 107 can be omitted. The disadvantage is that if the marking ring is embedded in the outer ring surface of the tube wire 101, Then, the structural strength of the tube wire 101 is reduced. If it is not embedded, it will protrude, and the two balloons and the metal stent 202 cannot be fully retracted to fit the outer ring surface of the tube wire 101 .

Second, as mentioned above, the marking ring can be provided on the outer ring surface and the inner ring surface of the inner tube 107. At this time, the disadvantages of the first method do not exist, but there is an additional structure of the inner tube 107. Moreover, the guide wire 4 for traction also needs to be passed through the inside, and the structural complexity and diameter of the entire drug balloon catheter are increased.

Finally, in order to cooperate with the insertion and installation of the inner tube 107, the guide wire through hole 102 can be provided with a constricted "step" at the front end to ensure that the inner tube 107 has a fixed insertion end point, so that The positions of the drug marking ring 203 and the occlusion marking ring 302 can be easily positioned.

The combined three-tube unit 5 includes a middle tube body 501 for connecting with the guide wire through hole 102, and is used for inserting the traction guide wire 4, which is arranged on the middle tube body 501 and is connected to the treatment hole. The first side pipe 502 of 103 and the second side pipe 503 arranged on the middle pipe body 501 and connected to the blocking hole 104 .

In this embodiment, the material of the combined three-pipe unit 5 may be medical grade PP resin to ensure proper hardness. And the nozzles of the first side tube 502 and the second side tube 503 are respectively connected with normal saline or contrast medium for pressurization, so as to ensure that the corresponding non-compliant balloon 201 and compliant balloon 301 can be Controlled expansion and contraction.

The three-lumen tube unit 1 further includes an insertion tip 108 arranged on the tube wire 101 , and a middle guide wire hole 109 arranged in the insertion tip 108 .

In this embodiment, the insertion tip 108 and the tube wire 101 may be welded later, or may be integrally formed at the beginning, and the traction guide wire 4 passes through the middle tube body 501, The guide wire through hole 102 and the middle guide wire hole 109 protrude at the front end, which can play a traction effect in the insertion action of the drug balloon catheter.

The diameter of the middle guide wire hole 109 is smaller than that of the guide wire through hole 102 .

In this embodiment, the diameter of the middle guide wire hole 109 is smaller than that of the guide wire through hole 102 , that is, to form the above-mentioned “stepped” structure and ensure that the insertion action of the inner tube 107 has a fixed end point.

Moreover, the biggest advantage of this arrangement is that the positions of the drug marking ring 203 and the blocking marking ring 302 on the inner tube 107 are the positions of the marking ring on the tube wire 101, and the two do not need to be converted.

The front occlusion balloon unit 3 further includes two assembling pressure rings 303 respectively disposed at both ends of the compliant balloon 301 and used to embed the tubing wire 101 .

In this embodiment, the mounting ring 303 is the mounting ring of the compliant balloon 301 , which ensures that both ends of the compliant balloon 301 are firmly fixed and sufficiently sealed.

A three-cavity connecting hose 6 is also provided between the middle pipe body 501 and the pipe wire 101 .

In this embodiment, after the guide wire 4 for traction is installed in the drug balloon catheter, the insertion action into the blood vessel can be performed. At this time, the combined three-tube unit 5 and the tube wire 101 do not need to be aligned. Therefore, the relatively soft three-chamber connection hose 6 can be used to ensure that the adding and discharging actions of normal saline or contrast agent are effective.

Moreover, the addition of the three-cavity connecting hose 6 improves the "hard-hard" connection between the pipe wire 101 and the combined three-tube unit 5 to a "hard-soft-hard" connection, which is more convenient and has higher sealing performance. .

Finally, the general use method and advantages of the drug balloon catheter are as follows.

First, the guide wire 4 for traction is protruded from the insertion tip 108 to complete the pre-use installation operation of the drug balloon catheter.

Second, under the monitoring of X-rays, the drug balloon catheter is inserted into the blood vessel until the vascular lesions come between the two drug marking rings 203 .

Third, the second side tube 503 is inflated with pressure, so that the compliant balloon 301 expands, blocks the blood vessel, and reduces the blood flow speed.

Fourth, the second side tube 503 is held, and then the first side tube 502 is inflated to inflate the non-compliant balloon 201, and the metal stent 202 is indirectly expanded, so that the The vascular plaque is squeezed and divided, and all the drugs on the surface of the non-compliant balloon 201 are released to the vascular lesions.

Fifth, the pressure of the second side tube 503 is first decompressed, and then the pressure of the second side tube 503 is decompressed, and the entire drug balloon catheter is returned to the initial state, and finally withdrawn.

The embodiments of the present invention have been described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above-mentioned embodiments, and within the scope of knowledge possessed by those of ordinary skill in the technical field, it can also be done without departing from the purpose of the present invention. various modifications. These are all non-creative modifications, as long as they are within the scope of the claims of the present invention, they are protected by the patent law.

Claims (10)

1. A medicine balloon catheter with blood blocking and plaque cutting functions is characterized in that: including three lumen tube unit (1), set up on three lumen tube unit (1) for back support sacculus unit (2) of operation is paintd to plaque cutting, medicine are carried out at vascular pathological change position sets up three lumen tube unit (1) is last, and be used for blockking preceding shutoff sacculus unit (3) of blood before back support sacculus unit (2) expandes, set up and be in lead wire (4) for pulling in three lumen tube unit (1), and set up and be in three lumen tube unit (1) insert the rear end, and be used for right back support sacculus unit (2) and preceding shutoff sacculus unit (3) fill the pressure release operation, right it inserts three tub of unit (5) of combination of installation operation with lead wire (4) for pulling.

2. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 1, wherein: three lumen unit (1) are including using wire rod (101), set up guide wire through-hole (102) in using wire rod (101), set up in using wire rod (101), and be used for right after support sacculus unit (2) carry out the treatment of inflating and releasing pressure operation with pore (103), set up in using wire rod (101), and be used for right before shutoff sacculus unit (3) carry out the shutoff with pore (104) of inflating and releasing pressure operation, set up rear end hole (105) on the treatment with pore (103), and set up front end hole (106) on the pore (104) are used in the shutoff.

3. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 2, wherein: the rear stent balloon unit (2) comprises a wire (101) which is sleeved on the tube, covers the rear end hole (105), a non-compliant balloon (201) with two closed ends, a drug layer arranged on the outer surface of the non-compliant balloon (201), a non-compliant balloon (201) which is sleeved on the outer side, and two ends of the non-compliant balloon (201) are fixedly connected with a metal stent (202) of the wire (101) for the tube, and are arranged on the wire (101) for the tube, and are respectively positioned on two drug marking rings (203) at two side positions of the rear end hole (105).

4. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 3, wherein: the front plugging balloon unit (3) comprises a compliance balloon (301) which is sleeved on the wire (101) for the tube, covers the front end hole (106) and is closed at two ends, and a plugging marking ring (302) arranged on the wire (101) for the tube.

5. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 4, wherein: the three-cavity tube unit (1) further comprises an inner tube (107) which is arranged in the guide wire through hole (102) and is used for installing the medicine marking ring (203) and the blocking marking ring (302).

6. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 2, wherein: the combined three-tube unit (5) comprises a middle tube body (501) which is butted with the guide wire through hole (102) and is used for inserting the traction guide wire (4), a first side tube (502) which is arranged on the middle tube body (501) and is butted with the therapeutic hole channel (103), and a second side tube (503) which is arranged on the middle tube body (501) and is butted with the plugging hole channel (104).

7. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 2, wherein: the three-lumen tube unit (1) further includes an insertion tip (108) provided on the tube wire (101), and a middle guide wire hole (109) provided in the insertion tip (108).

8. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 7, wherein: the aperture of the middle wire guide hole (109) is smaller than that of the wire guide through hole (102).

9. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 4, wherein: the front plugging balloon unit (3) further comprises two assembling press rings (303) which are respectively arranged at two ends of the compliance balloon (301) and used for embedding the wire (101) for the tube.

10. The drug balloon catheter with the functions of blood blocking and plaque cutting as claimed in claim 6, wherein: and a three-cavity connecting hose (6) is further arranged between the middle pipe body (501) and the pipe wire (101).

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