CN116124712A - Device capable of measuring urine sugar concentration - Google Patents
Device capable of measuring urine sugar concentration Download PDFInfo
- Publication number
- CN116124712A CN116124712A CN202111345520.2A CN202111345520A CN116124712A CN 116124712 A CN116124712 A CN 116124712A CN 202111345520 A CN202111345520 A CN 202111345520A CN 116124712 A CN116124712 A CN 116124712A
- Authority
- CN
- China
- Prior art keywords
- light
- incident
- prism body
- transmitting surface
- urine sugar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
本发明揭露一种可量测尿糖浓度装置,包含棱镜本体及壳体。棱镜本体包含第一容置空间、交界面、第一透光面、第二透光面、第三透光面及出光面。第一容置空间容置尿液。交界面形成于第一容置空间底面。第一透光面形成于第一容置空间的第一侧面。第二透光面相对第一透光面形成于第一容置空间的第二侧面。第三透光面相对交界面设置。出光面与交界面对应设置。壳体包含第二容置空间、第一出光口及第二出光口。第二容置空间容置棱镜本体。第一出光口具有第一口径,并与棱镜本体之出光面对应设置。第二出光口具有第二口径,并与第一出光口对应设置,其中第一口径小于或等于第二口径。
The invention discloses a device capable of measuring urine sugar concentration, which includes a prism body and a casing. The prism body includes a first accommodating space, an interface, a first light-transmitting surface, a second light-transmitting surface, a third light-transmitting surface and a light-emitting surface. The first accommodation space accommodates urine. The interface is formed on the bottom surface of the first accommodating space. The first light-transmitting surface is formed on a first side surface of the first accommodating space. The second light-transmitting surface is formed on a second side of the first accommodating space opposite to the first light-transmitting surface. The third transparent surface is arranged opposite to the interface. The light-emitting surface and the interface are set correspondingly. The casing includes a second accommodating space, a first light outlet and a second light outlet. The second accommodating space accommodates the prism body. The first light outlet has a first aperture and is set corresponding to the light outlet surface of the prism body. The second light outlet has a second diameter and is set corresponding to the first light outlet, wherein the first diameter is smaller than or equal to the second diameter.
Description
技术领域technical field
本发明有关于一种可量测液体浓度的装置,特别是有关于一种可量测尿糖浓度装置。The present invention relates to a device capable of measuring liquid concentration, in particular to a device capable of measuring urine sugar concentration.
背景技术Background technique
尿糖的数值高低表示肾丝球、滤过血液内糖分过高,使得肾小管无法全部吸收,而由尿液排出称为尿糖。一般而言,血糖超过180mg/dL时,则尿液会出现糖分。如果检测尿糖的结果出现阳性,表示受测者可能具有糖尿病、胰脏炎、肝病变、甲状腺疾病等风险。The high or low value of urine sugar indicates that the glomerular and filtrated blood sugar is too high, so that the renal tubules cannot fully absorb it, and it is excreted in urine as urine sugar. Generally speaking, when the blood sugar exceeds 180mg/dL, there will be sugar in the urine. If the urine sugar test results are positive, it means that the subject may have risks such as diabetes, pancreatitis, liver disease, and thyroid disease.
尿糖偏高经常是判定为血糖偏高的因果关系之一,然而,因为目前血糖检查为侵入式抽取血液检测,造成受测者的心理负担,因而降低受测者持续进行检测的意愿。因此,常有受测者延误检测后,发现血糖偏高而已造成上述病变的情况发生。High urine sugar is often one of the causal relationships that determine high blood sugar. However, because the current blood sugar test is an invasive blood test, it causes a psychological burden on the subject, thus reducing the willingness of the subject to continue testing. Therefore, it is often found that the above-mentioned lesions have been caused by the high blood sugar level after the test subject delays the test.
此外,尿糖检测目前以酵素法为主,其中又以葡萄糖氧化酶法的试纸检测最普遍。然而,试纸检测虽然费用低廉,但对于终端使用者来说,试纸测定时间需要30-60秒,并无实时性。再者,人眼判读试纸颜色变化容易造成人为误差,因而缺乏效率。同时,试纸存在有保存问题,容易因为空气与湿气而劣化,因而影响尿糖性能的判断。In addition, the enzyme method is currently the main method for urine glucose detection, among which the glucose oxidase method is the most common. However, although the cost of test paper detection is low, for end users, the test paper measurement time needs 30-60 seconds, and there is no real-time performance. Furthermore, human eyes may easily cause human error when interpreting the color change of the test paper, thus lacking in efficiency. At the same time, there is a storage problem with the test paper, which is easy to deteriorate due to air and moisture, thus affecting the judgment of the performance of urine sugar.
由于国人糖尿病的情况普遍严重,因此,如何提供一种非侵入式检测装置,帮助受测者以非侵入式方式检测尿糖已成为目前急需研究的课题。Since diabetes is generally serious in Chinese people, how to provide a non-invasive detection device to help subjects detect urine sugar in a non-invasive manner has become an urgent research topic.
发明内容Contents of the invention
鉴于上述问题,本发明揭露一种可量测尿糖浓度装置,包含棱镜本体及壳体。棱镜本体包含第一容置空间、交界面、第一透光面、第二透光面、第三透光面及出光面。第一容置空间容置尿液。交界面形成于第一容置空间的底面。第一透光面形成于第一容置空间的第一侧面。第二透光面相对第一透光面形成于第一容置空间的第二侧面。第三透光面相对交界面设置。出光面与交界面对应设置。壳体包含第二容置空间、第一出光口及第二出光口。第二容置空间容置棱镜本体。第一出光口具有第一口径,并与棱镜本体的出光面对应设置。第二出光口具有第二口径,并与第一出光口对应设置,其中第一口径小于或等于第二口径。当第一入射光束入射至棱镜本体内部后,第一入射光束射向交界面,并由交界面反射到出光面后,由出光面射出棱镜本体内部,并通过第一出光口及第二出光口射出壳体内部。当第二入射光束入射棱镜本体内部后,第二入射光束射向第一透光面,并由第一透光面射出棱镜本体内部后,入射至第一容置空间,且穿透第一容置空间内的尿液,再入射至第二透光面,由第二透光面入射棱镜本体内部后,射向第三透光面,由第三透光面射出棱镜本体内部,其中可量测尿糖浓度装置根据射出该壳体内部的该第一入射光束计算一折亮度,以及根据射出该棱镜本体内部的该第二入射光束计算一吸亮度,并根据该折亮度及该吸亮度计算一尿糖浓度。In view of the above problems, the present invention discloses a device capable of measuring urine sugar concentration, which includes a prism body and a casing. The prism body includes a first accommodating space, an interface, a first light-transmitting surface, a second light-transmitting surface, a third light-transmitting surface and a light-emitting surface. The first accommodation space accommodates urine. The interface is formed on the bottom surface of the first accommodating space. The first light-transmitting surface is formed on a first side surface of the first accommodating space. The second light-transmitting surface is formed on a second side of the first accommodating space opposite to the first light-transmitting surface. The third transparent surface is arranged opposite to the interface surface. The light-emitting surface and the interface are set correspondingly. The casing includes a second accommodating space, a first light outlet and a second light outlet. The second accommodating space accommodates the prism body. The first light outlet has a first diameter and is arranged corresponding to the light outlet surface of the prism body. The second light outlet has a second diameter and is set corresponding to the first light outlet, wherein the first diameter is smaller than or equal to the second diameter. When the first incident light beam enters the interior of the prism body, the first incident light beam shoots to the interface, and is reflected by the interface to the light exit surface, then exits the interior of the prism body from the light exit surface, and passes through the first light exit port and the second light exit port Shoot out the inside of the shell. When the second incident light beam enters the inside of the prism body, the second incident light beam hits the first light-transmitting surface, and after exiting the interior of the prism body from the first light-transmitting surface, it enters the first accommodation space and penetrates the first accommodation space. The urine placed in the space enters the second light-transmitting surface, enters the interior of the prism body from the second light-transmitting surface, and then shoots to the third light-transmitting surface, and then exits the interior of the prism body from the third light-transmitting surface, which can be measured The urine sugar concentration measuring device calculates a refractive brightness according to the first incident light beam emitted from the inside of the housing, and calculates an absorption brightness according to the second incident light beam emitted from the inside of the prism body, and calculates according to the refractive brightness and the absorption brightness A urine sugar concentration.
承上所述,本发明可量测尿糖浓度装置可同时或者个别检测光线的折亮度与吸亮度,结合吸光与折光特性,可对尿液进行尿糖浓度分析,并且无需使用聚光元件作为光源,因而具有简化光路校正(alignment)的优点。再者,本发明可量测尿糖浓度装置无需设置透镜或目镜等结构,可使整体结构的体积缩小。此外,本发明可量测尿糖浓度装置无需使用滤片或偏极片等结构,可降低生产成本。再者,本发明可量测尿糖浓度装置针对尿糖的检测具有多项优点,包含不须添加化学试剂、不须试纸、通过仪器判读检测信息而降低人为判读误差、通过光学检测而无氧气与湿气劣化问题、通过光学检测可提高检测频率以及容易收集测试数据进行统计分析与实时健康管理。Based on the above, the device for measuring urine sugar concentration in the present invention can detect the refractive brightness and absorbance of light at the same time or individually. Combining light absorption and refractive properties, urine sugar concentration analysis can be performed on urine, and there is no need to use light-gathering elements as The light source thus has the advantage of simplifying the alignment of the optical path. Furthermore, the urine sugar concentration measuring device of the present invention does not need to be provided with structures such as lenses or eyepieces, which can reduce the volume of the overall structure. In addition, the urine sugar concentration measuring device of the present invention does not need to use structures such as filters or polarizers, which can reduce production costs. Furthermore, the device for measuring urine sugar concentration of the present invention has many advantages for the detection of urine sugar, including no need to add chemical reagents, no test paper, reduce human interpretation errors through instrument interpretation of detection information, and use optical detection without oxygen. With the problem of moisture degradation, the detection frequency can be improved through optical detection, and the test data can be easily collected for statistical analysis and real-time health management.
附图说明Description of drawings
图1A及图1B为本发明可量测尿糖浓度装置的第一立体图及第二立体图;1A and FIG. 1B are the first perspective view and the second perspective view of the device for measuring urine sugar concentration of the present invention;
图2A至图2D为本发明可量测尿糖浓度装置的立体图、分解图、上视图及剖视图;2A to 2D are perspective views, exploded views, top views and cross-sectional views of the device for measuring urine sugar concentration of the present invention;
图3A及图3B为本发明可量测尿糖浓度装置的光线反射示意图及光线穿透液体示意图;3A and 3B are schematic diagrams of light reflection and light penetration through liquid of the device for measuring urine sugar concentration of the present invention;
图4A至图4C为本发明可量测尿糖浓度装置的反射光线示意图;4A to 4C are schematic diagrams of reflected light of the apparatus for measuring urine sugar concentration of the present invention;
图5A至图5D为本发明第一入射光束入射到可量测尿糖浓度装置的示意图;5A to 5D are schematic diagrams of the first incident light beam incident on the device capable of measuring urine sugar concentration according to the present invention;
图6为本发明尿液浓度与吸亮度的关系示意图;Fig. 6 is a schematic diagram of the relationship between urine concentration and absorbance of the present invention;
图7为本发明尿糖浓度与吸亮度及折亮度的关系示意图;以及Fig. 7 is a schematic diagram of the relationship between urine sugar concentration, absorption brightness and refractive brightness of the present invention; and
图8为本发明可量测尿糖浓度装置方块示意图。FIG. 8 is a schematic block diagram of a device capable of measuring urine sugar concentration according to the present invention.
[符号说明][Symbol Description]
3:可量测尿糖浓度装置3: Measuring urine sugar concentration device
1:棱镜本体1: Prism body
10:第一容置空间10: The first storage space
11:第一透光面11: The first light-transmitting surface
12:第二透光面12: The second transparent surface
13:第三透光面13: The third transparent surface
14:出光面14: Light-emitting surface
15:入光面15: light incident surface
16:第一反光面16: The first reflective surface
17:第二反光面17: Second reflective surface
Q:尿液Q: Urine
100:交界面100: interface
S1:第一光源S1: the first light source
S2:第二光源S2: Second light source
L1:第一入射光束L1: first incident beam
L2:第二射光束L2: second beam
D1:第一光线传感器D1: the first light sensor
D2:第二光线传感器D2: Second light sensor
2:壳体2: shell
20:第二容置空间20: The second storage space
21:第一出光口21: The first light outlet
22:第二出光口22: Second light outlet
23:启动键23: start button
24:显示单元24: Display unit
25:电源键25: Power key
26:外壁26: outer wall
261:穿孔261: perforation
27:第一容置槽27: The first storage tank
28:第二容置槽28: The second storage tank
30:篓空空间30: empty space
31:输入单元31: Input unit
32:检测单元32: Detection unit
33:处理单元33: Processing unit
θ:预设倾斜角度θ: preset tilt angle
θ1:第一夹角θ1: the first included angle
θ2:第二夹角θ2: second included angle
A,B,C:尿糖特性曲线A, B, C: urine sugar characteristic curve
具体实施方式Detailed ways
请参阅图1A及图1B,其为本发明可量测尿糖浓度装置的棱镜本体的第一立体图及第二立体图。棱镜本体1包含第一容置空间10、第一透光面11、第二透光面12、第三透光面13及出光面14。第一容置空间10容置尿液Q。交界面100形成于第一容置空间10的底面。第一透光面11形成于第一容置空间10的第一侧面。第二透光面12相对第一透光面11形成于第一容置空间10的第二侧面。第三透光面13相对交界面100设置。出光面14与交界面100对应设置。Please refer to FIG. 1A and FIG. 1B , which are the first perspective view and the second perspective view of the prism body of the urine sugar concentration measuring device of the present invention. The
请参阅图2A至图2D,其为本发明可量测尿糖浓度装置的立体图、分解图、上视图及剖视图。可量测尿糖浓度装置3包含棱镜本体1及壳体2。壳体2包含第二容置空间20、第一出光口21及第二出光口22。第二容置空间20容置棱镜本体1。第一出光口21具有第一口径,并与棱镜本体1的出光面14对应设置。第二出光口22具有第二口径,并与第一出光口21对应设置,其中第一口径小于或等于第二口径。再者,于本发明的一实施例中,第一出光口21为单狭缝的形状,且第一出光口21与第二出光口22形成喇叭状开口,亦即第一出光口21到第二出光口22的口径大小由窄逐渐变宽。此外,壳体2更包含一启动键23、一显示单元24以及一电源键25。启动键23控制第一光源S1、第一光线传感器D1、第二光源S2、第二光线传感器D2及显示单元24的开启与关闭。显示单元24显示尿液的量测数据结果,亦即显示尿糖浓度数值。电源键25电性连接供电单元(未图标),供电单元电性连接显示单元24、启动键25以及各个光源,以供给该些元件电力。Please refer to FIG. 2A to FIG. 2D , which are perspective views, exploded views, top views and cross-sectional views of the device for measuring urine sugar concentration of the present invention. The
请参阅图2B,可量测尿糖浓度装置更包含一外壁26、一第一光源S1、一第一光线传感器D1、一第二光源S2以及一第二光线传感器D2。外壁26贴合壳体2的一表面及棱镜本体1的入光面15(如图1A所示),以形成棱镜本体1的第一容置空间10。进一步而言,由于棱镜本体1的第一容置空间10为一开放空间,因此,于本发明的一实施例中,通过外壁26贴合棱镜本体1的入光面15,使第一容置空间10成为可容置尿液的一容置空间。于本发明其它实施例中,棱镜本体1的第一容置空间10亦可为一可容置尿液的封闭空间。第一光源S1设置于外壁26上、交界面100下方的位置,产生第一入射光束L1。换句话说,第一入射光束L1由下往上入射到交界面100。第一光线传感器D1设置于第二出光口22上,接收第一入射光束L1,其中壳体2的表面平行于第二出光口22。壳体2更包含第一容置槽27及第二容置槽28,第二光源S2设置于壳体2的第一容置槽27中,产生第二入射光束L2。第二光线传感器D2设置于壳体2的第二容置槽28中,接收第二入射光束L2,其中第一容置槽27与第二容置槽28平行设置。Please refer to FIG. 2B , the urine sugar concentration measuring device further includes an outer wall 26 , a first light source S1 , a first light sensor D1 , a second light source S2 and a second light sensor D2 . The outer wall 26 is attached to a surface of the
请参阅图2D,棱镜本体1的出光面14与壳体2第二容置空间20的底部表面形成篓空空间30,其为光线传递的空间,使第一入射光束L1由棱镜本体1的出光面14射出棱镜本体1内部后,通过篓空空间30、第一出光口21及第二出光口22射出壳体2内部,并射向设置于第二出光口22上的第一光线传感器D1。Please refer to Fig. 2D, the
请参阅图3A及图3B,其为本发明可量测尿糖浓度装置的光线反射示意图及光线穿透液体示意图。如图3A所示,并配合参阅图2D,第一光源S1产生的第一入射光束L1入射至棱镜本体1内部后,第一入射光束L1射向交界面100,并由交界面100反射到出光面14后,由出光面14射出棱镜本体1内部,并通过第一出光口21及第二出光口22入射到设置于壳体2出光口22的第一光线传感器D1,借此量测尿液Q的折亮度。如图3B所示,并配合参阅图2B,第二光源S2产生的第二入射光束L2入射棱镜本体内部后,第二入射光束L2射向第一透光面11,并由第一透光面11射出棱镜本体内部后,入射至第一容置空间10,且穿透第一容置空间10内的尿液Q,再入射至第二透光面12,由第二透光面12入射棱镜本体内部后,射向第三透光面13,由第三透光面13射出棱镜本体内部,并入射到设置于壳体2内的第二光线传感器D2。尿液Q的浓度借由第一光线传感器D1量测穿出该出光面14、第一出光口21及第二出光口22的第一入射光束L1计算,尿液Q的吸亮度借由第二光线传感器D2量测穿出第三透光面13的第二入射光束D2计算。Please refer to FIG. 3A and FIG. 3B , which are schematic diagrams of light reflection and light penetration through liquid of the device for measuring urine sugar concentration of the present invention. As shown in Figure 3A, and with reference to Figure 2D, after the first incident light beam L1 generated by the first light source S1 enters the interior of the prism body 1, the first incident light beam L1 is directed to the interface 100, and is reflected by the interface 100 to the outgoing light After the surface 14, the light exits the interior of the prism body 1 from the light exit surface 14, and enters the first light sensor D1 provided at the light exit 22 of the housing 2 through the first light exit 21 and the second light exit 22, thereby measuring urine The folded brightness of Q. As shown in Figure 3B, and with reference to Figure 2B, after the second incident light beam L2 generated by the second light source S2 enters the inside of the prism body, the second incident light beam L2 shoots to the first light-transmitting surface 11, and is transmitted from the first light-transmitting surface 11 After exiting the interior of the prism body, it enters the first accommodating space 10, and penetrates the urine Q in the first accommodating space 10, and then enters the second light-transmitting surface 12, and enters the prism from the second light-transmitting surface 12 After the inside of the main body, it is emitted to the third light-transmitting surface 13 , and then exits the interior of the prism body from the third light-transmitting surface 13 , and enters the second light sensor D2 disposed in the casing 2 . The concentration of urine Q is calculated by the first light sensor D1 measuring the first incident light beam L1 passing through the
承上所述,根据基本光学原理可知,光线进入到不同介质中,光线会产生折射现象,同时也会产生反射,因此,将第一光线传感器D1设置在壳体的第二出光口22,借由量测接收到反射的第一入射光束L1的光线亮度(折亮度)可计算出尿液Q浓度。此外,当光线穿透过尿液Q后,由于尿液Q会吸收光线能量,使得光线亮度减弱,因此,将第二光线传感器D2设置在壳体上,借由量测接收到第二入射光束L2的光线亮度可计算出尿液Q的吸亮度。Based on the above, according to the basic optical principle, it can be known that when light enters different media, the light will be refracted and reflected at the same time. The concentration of urine Q can be calculated by measuring the brightness (refractive brightness) of the reflected first incident light beam L1. In addition, when the light passes through the urine Q, since the urine Q will absorb the energy of the light, the brightness of the light will be weakened. Therefore, the second light sensor D2 is arranged on the housing to receive the second incident light beam by measuring The light brightness of L2 can calculate the absorption brightness of urine Q.
如图1A、图1B及图3A所示,棱镜本体1更包含一入光面15,邻接交界面100。于本发明的一实施例中,入光面15垂直相邻连接交界面100。第一光源S1的第一入射光束L1经由入光面15入射至棱镜本体1内部,再射向交界面100。As shown in FIG. 1A , FIG. 1B and FIG. 3A , the
如图1A、图1B及图3B所示,第三透光面13邻接入光面15。于本发明的一实施例中,第三透光面13与入光面15垂直邻接,且第二入射光束L2自第三透光面13入射棱镜本体1内部后,再射向第一透光面11。As shown in FIG. 1A , FIG. 1B and FIG. 3B , the third light-transmitting
如图3A所示,出光面14邻接第三透光面13,且出光面14与入光面15分别邻接于第三透光面13的相对两侧。出光面14与第三透光面13之间具有一夹角θ,且该夹角θ为钝角,介于105度至165度之间。于本发明的一较佳实施例中,该夹角θ为135度。As shown in FIG. 3A , the light-emitting
请参阅图3B,棱镜本体1更包含第一反光面16及第二反光面17。当第二光源S2产生的第二入射光束L2入射棱镜本体1内部后,第二入射光束L2先射向第一反光面16,并于通过第一反光面16反射后,射向第一透光面11,由第一透光面11射出棱镜本体1内部后,入射至第一容置空间10,且穿透第一容置空间10内的尿液Q,再入射至第二透光面12,由第二透光面12入射棱镜本体1内部后,射向第二反光面17,再通过第二反光面17反射后,射向第三透光面13,再由第三透光面13射出棱镜本体1内部,并入射到设置于壳体2内的第二光线传感器D2。第一反光面16邻接第一透光面11,并与第一透光面之间具有第一夹角θ1,第一夹角θ1为锐角,介于15度至75度之间。于本发明的一较佳实施例中,第一夹角θ1较佳为45度。第一反光面16根据第二入射光束L2入射第三透光面13的角度,以第一夹角θ1设置。第二反光面17邻接第二透光面12,并与第二透光面12之间具有第二夹角θ2,第二夹角θ2为锐角,介于15度至75度之间。于本发明的一较佳实施例中,第二夹角θ2较佳为45度。第二反光面17根据第二入射光束L2入射第一反光面16后反射的角度,以第二夹角θ2设置。Please refer to FIG. 3B , the
请再参阅图3A及图3B,壳体在本发明之实施例中,第一反光面16及第二反光面17分别为一三角块的形状设置围绕于第一容置空间10周围的两侧面,并与第一容置空间10的交界面100(底面)形成该第一容置空间10。需注意的是,虽然第一容置空间10在本发明的图式中并无法以第一三角块、第二三角块以及另一凸块围绕形成封闭的空间,但事实上棱镜本体1设置于壳体2的第二容置空间20中,且入光面15与壳体2第二容置空间20内的壁面贴合,因而使得棱镜本体1的第一容置空间10围绕成一封闭空间,以容置尿液Q。Please refer to FIG. 3A and FIG. 3B again. In the embodiment of the present invention, the first
请参阅图4A至图4C,其为本发明可量测尿糖浓度装置的反射光线示意图。如图所示,棱镜本体1的出光面14设置在相对入光面15的一侧,由交界面100反射的第一入射光束L1通过出光面14、壳体2的第一出光口21及第二出光口22后,入射到第一光线传感器D1。由光学原理可知,欲量测通过出光面14、第一出光口21及第二出光口22的第一入射光束L1,必须针对出光面14的设置角度及面积以及第一出光口21及第二出光口22的口径进行配置。进一步而言,根据斯涅尔定律(Snell′s Law),已知棱镜本体1的介质折射率以及第一入射光束L1入射到交界面100的入射角,可根据第一入射光束L1在通过不同介质折射率(不同溶液)的交界面100时所产生的反射角度范围计算出尿液Q的介质折射率。而尿液Q折射率越大,被折射的光线越多,相对的反射光越少,第一光线传感器D1所接收到第一入射光束L1的反射光线越少(如图4A及图4B所示),因此,可进一步根据第一入射光束L1入射到不同尿液Q的介质折射率的范围,所对应产生的反射角度范围,定义、配置出光面14的默认倾斜角度θ及面积,以及计算出第一出光口21及第二出光口22的口径大小,亦即,出光面14的预设倾斜角度θ以及预设面积以及第一出光口21及第二出光口22的口径根据第一入射光束L1从交界面100所产生的反射角度设置,且预设倾斜角度θ以交界面100为基准角度设置。Please refer to FIG. 4A to FIG. 4C , which are schematic diagrams of reflected light of the apparatus for measuring urine sugar concentration of the present invention. As shown in the figure, the
在本发明的较佳实施例中,第一光源S1设置于壳体2的外壁26的一穿孔261内,并对应棱镜本体1入光面15中心的法线位置设置,以使第一入射光束L1能平均入射入光面15。第一光线传感器D1设置在壳体2第二出光口22上,借此能平均接收通过出光面14、第一出光口21及第二出光口22的第一入射光束L1。In a preferred embodiment of the present invention, the first light source S1 is arranged in a through
请参阅图5A至图5D,其为本发明第一入射光束入射到可量测尿糖浓度装置的示意图。实际上,为了要量测第一入射光束L1入射到棱镜本体1后的反射光,以及量测第二光束L2穿透过尿液Q后的光线,于本发明的实施例中,第一光源S1及第二光源S2包含卤素灯、气体灯、镭射、LED、或者其他发光元件。而针对第一入射光束L1入射到棱镜本体1后的反射光,由于使用的该些光源所产生的光束向外360度发出,而对于前半部入射到棱镜本体1的光线而言,可将其区分为如图5A至图5D四个部分的光线。如图5A所示,当第一入射光束L1入射到棱镜本体1的交界面100后,其反射光朝向出光面14射出,并入射到第一光线传感器D1。如图5B所示,当第一入射光束L1入射到棱镜本体1后,由于在入射方向上并无可使其产生反射的表面或交界面100,因此,其入射光束直接朝向棱镜本体1的外部射出。如图5C所示,当第一入射光束L1入射到棱镜本体1的出光面14后,由于第一入射光束L1的入射角度正好与出光面14形成全反射的角度,因而使得反射的第一入射光束L1朝向棱镜本体1的其它方向射入,并朝向棱镜本体1的外部射出。如图5D所示,当第一入射光束L1入射到棱镜本体1的第三透光面13后,其产生的反射光角度并未朝向出光面14射出,而是朝向棱镜本体1的其它方向向外射出。据此,设置于第二出光口22的第一光线传感器D1仅接收入射到棱镜本体1交界面100后的反射光。Please refer to FIG. 5A to FIG. 5D , which are schematic diagrams of the first incident light beam incident on the device for measuring urine sugar concentration according to the present invention. In fact, in order to measure the reflected light of the first incident light beam L1 incident on the
请参阅图6,其为本发明尿液浓度与吸亮度的关系示意图。由于尿液Q浓度会造成吸亮度的差异,因此,借由量测尿液Q的吸亮度可计算该尿液Q浓度。根据比尔-朗伯定理(Beer–Lambert law),当一平行光线垂直入射样品后,样品的吸光物质吸收部分光子能量,使透射光强度减弱,其中被吸收的能量(A)与样品吸收系数(α)、光程(样品长度)(L)、浓度(c)三着呈现正相关,表示方法如下:Please refer to FIG. 6 , which is a schematic diagram of the relationship between urine concentration and absorbance in the present invention. Since the concentration of urine Q will cause a difference in absorbance, the concentration of urine Q can be calculated by measuring the absorbance of urine Q. According to the Beer–Lambert law, when a parallel light is incident on the sample vertically, the light-absorbing substance of the sample absorbs part of the photon energy, which weakens the intensity of the transmitted light. The absorbed energy (A) is related to the sample absorption coefficient ( α), optical path (sample length) (L), and concentration (c) are positively correlated, expressed as follows:
A=αLcA=αLc
被吸收的能量可视为吸收度(A),因此当光线穿过样品部分能量被样品吸收,剩下的光线穿透该样品,因此可以从入射光(I0)与透射光(I)的能量差来计算出该样品吸收度,其吸收度定义如下The absorbed energy can be regarded as the absorbance (A), so when the light passes through the sample, part of the energy is absorbed by the sample, and the rest of the light passes through the sample, so the energy of the incident light (I0) and the transmitted light (I) can be The absorbance of the sample is calculated by the difference, and the absorbance is defined as follows
再者,第二入射光束L2入射至第一反光面16后,经过第一反光面16反射后透射至尿液Q,尿液Q吸收部分光子能量,使透射光强度减弱,再经过第二反光面17反射到第二光线传感器D2。尿液Q浓度越高,被吸收的光线能量越多,因此透射光强度越弱,从光源强度与透射光的比例可得知吸收度,进而计算出尿液Q浓度。Moreover, after the second incident light beam L2 is incident on the first
请参阅图7,其为本发明尿糖浓度与吸亮度及折亮度的关系示意图。由于尿液Q的浓度不同,光线的吸光比率也会不同,因此,不同的尿液浓度会有不同的尿糖特性曲线A、B、C。而本发明能量测尿液的吸亮度与折亮度,并通过量测尿液的吸亮度判断尿糖特性曲线A、B、C后,再借由量测光线进入尿液Q后的折射率,即尿液的折亮度,根据折射率及依据吸亮度判断出的尿糖特性曲线A、B、C,计算出对应的尿糖浓度。于本发明的一实施例中,壳体2更包含一储存模块(未图标),储存一数据库,数据库包含多条尿糖特性曲线,以供处理模块快速计算及比对对应的尿糖浓度。Please refer to FIG. 7 , which is a schematic diagram of the relationship between urine sugar concentration, absorbance and refraction in the present invention. Since the concentration of urine Q is different, the light absorption ratio of light will also be different. Therefore, different urine concentrations will have different urine sugar characteristic curves A, B, and C. However, the present invention can measure the absorption brightness and refractive brightness of urine, and judge the urine sugar characteristic curves A, B, and C by measuring the absorption brightness of urine, and then measure the refractive index after the light enters the urine Q, That is, the refractive brightness of urine, according to the refractive index and the urine sugar characteristic curves A, B, and C judged from the absorption brightness, the corresponding urine sugar concentration is calculated. In an embodiment of the present invention, the
举例来说,尿糖特性曲线A对应的吸亮度为a%,尿糖特性曲线B对应的吸亮度为b%,尿糖特性曲线C对应的吸亮度为c%,且a>b>c,而通过本发明量测到的尿液折亮度为n。据此,在计算尿糖浓度时,即可根据上述内容计算出的吸亮度a%先决定出尿糖特性曲线A,再根据尿糖特性曲线A以及计算出的折亮度为n,计算出对应的尿糖浓度为x(mg/dl)。For example, the absorbance corresponding to the urine sugar characteristic curve A is a%, the absorbance corresponding to the urine sugar characteristic curve B is b%, the absorbance corresponding to the urine sugar characteristic curve C is c%, and a>b>c, And the urine refractive brightness measured by the present invention is n. Accordingly, when calculating the urine sugar concentration, the urine sugar characteristic curve A can be determined based on the absorbance a% calculated from the above content, and then the corresponding The urine sugar concentration is x (mg/dl).
请参阅图8,其为本发明可量测尿糖浓度装置方块示意图。可量测尿糖浓度装置3更包含一输入单元31、一检测单元32以及一处理单元33,输入单元31电性连接供电单元,包含第一光源S1及第二光源S2,产生启动讯号触发第一光源S1及第二光源S2。检测单元32包含第一光线传感器D1、第二光线传感器D2,电性连接供电单元及输入单元31,分别接收及感测第一光源S1及第二光源S2发射的第一入射光束L1及第二入射光束L2,经过尿液、棱镜本体1的交界面100产生透射、反射及折射的光线。处理单元33电性连接检测单元32及显示单元24,并根据第一光线传感器D1接收的第一入射光束L1计算折亮度,以及根据第二光线传感器D2接收的第二入射光束L2计算吸亮度,并将计算结果显示在显示单元24上。Please refer to FIG. 8 , which is a schematic block diagram of a device for measuring urine sugar concentration according to the present invention. The urine sugar
于本发明的一实施例中,棱镜本体1材质包含玻璃、塑料、或者其他可透光材料。棱镜本体1的交界面100、第一透光面11、第二透光面12、第三透光面13、出光面14、入光面15、第一反光面16及第二反光面17可为光滑面、粗糙面、镀膜面、遮挡面、或者其他处理方式的表面。棱镜本体1加工的方式包含研磨、胶合、模造、射出、或者其他加工方式。In an embodiment of the present invention, the material of the
于本发明的一实施例中,第一光线传感器D1及第二光线传感器D2包含光侦测二极管、光侦测二极管阵列、光谱仪、CCD传感器、或者其他感光元件。In an embodiment of the present invention, the first light sensor D1 and the second light sensor D2 include photodetection diodes, photodetection diode arrays, spectrometers, CCD sensors, or other photosensitive elements.
综上所述,本发明可量测尿糖浓度装置可同时或者个别检测光线的折亮度与吸亮度,结合吸光与折光特性,可对尿液进行尿糖浓度分析,并且无需使用聚光元件作为光源,因而具有简化光路校正(alignment)的优点。再者,本发明可量测尿糖浓度装置无需设置透镜或目镜等结构,可使整体结构的体积缩小。此外,本发明可量测尿糖浓度装置无需使用滤片或偏极片等结构,可降低生产成本。再者,本发明可量测尿糖浓度装置针对尿糖的检测具有多项优点,包含不须添加化学试剂、不须试纸、通过仪器判读检测信息而降低人为判读误差、通过光学检测而无氧气与湿气劣化问题、通过光学检测可提高检测频率以及容易收集测试数据进行统计分析与实时健康管理。In summary, the device for measuring urine sugar concentration of the present invention can detect the refractive brightness and absorption brightness of light at the same time or individually, and combine the light absorption and refractive properties to analyze urine sugar concentration without using a light-gathering element as a The light source thus has the advantage of simplifying the alignment of the optical path. Furthermore, the urine sugar concentration measuring device of the present invention does not need to be provided with structures such as lenses or eyepieces, which can reduce the volume of the overall structure. In addition, the urine sugar concentration measuring device of the present invention does not need to use structures such as filters or polarizers, which can reduce production costs. Furthermore, the device for measuring urine sugar concentration of the present invention has many advantages for the detection of urine sugar, including no need to add chemical reagents, no test paper, reduce human interpretation errors through instrument interpretation of detection information, and use optical detection without oxygen. With the problem of moisture degradation, the detection frequency can be improved through optical detection, and the test data can be easily collected for statistical analysis and real-time health management.
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111345520.2A CN116124712A (en) | 2021-11-15 | 2021-11-15 | Device capable of measuring urine sugar concentration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111345520.2A CN116124712A (en) | 2021-11-15 | 2021-11-15 | Device capable of measuring urine sugar concentration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116124712A true CN116124712A (en) | 2023-05-16 |
Family
ID=86306719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111345520.2A Pending CN116124712A (en) | 2021-11-15 | 2021-11-15 | Device capable of measuring urine sugar concentration |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116124712A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1151861A (en) * | 1997-08-01 | 1999-02-26 | Shiroki Corp | Apparatus for measuring concentration of liquid |
| CN101379386A (en) * | 2005-12-22 | 2009-03-04 | 霍尼韦尔国际公司 | Portable sample analyzer system |
| US20140118745A1 (en) * | 2011-06-30 | 2014-05-01 | Koninklijke Philips N.V. | Multiple examinations of a sample |
| US20170205338A1 (en) * | 2016-01-18 | 2017-07-20 | Sentelligence, Inc. | Sensor system for multi-component fluids |
| CN207816809U (en) * | 2018-02-13 | 2018-09-04 | 中国海洋石油集团有限公司 | A kind of fluid analysis optical system |
-
2021
- 2021-11-15 CN CN202111345520.2A patent/CN116124712A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1151861A (en) * | 1997-08-01 | 1999-02-26 | Shiroki Corp | Apparatus for measuring concentration of liquid |
| CN101379386A (en) * | 2005-12-22 | 2009-03-04 | 霍尼韦尔国际公司 | Portable sample analyzer system |
| US20140118745A1 (en) * | 2011-06-30 | 2014-05-01 | Koninklijke Philips N.V. | Multiple examinations of a sample |
| US20170205338A1 (en) * | 2016-01-18 | 2017-07-20 | Sentelligence, Inc. | Sensor system for multi-component fluids |
| CN207816809U (en) * | 2018-02-13 | 2018-09-04 | 中国海洋石油集团有限公司 | A kind of fluid analysis optical system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2558862T3 (en) | Multiple wavelength reading head for use in the determination of analytes in body fluids | |
| US7271883B2 (en) | Refractive index sensor using internally reflective light beams | |
| AU2017266883B2 (en) | Evanescent hemolysis detection | |
| CN1413298A (en) | Test element analysis system | |
| CN105266824A (en) | Non-invasive blood glucose monitoring device and method and analysis method of biochemical molecules | |
| JP3881960B2 (en) | Portable automatic refractometer | |
| MX2013014553A (en) | Multiple examinations of a sample. | |
| CN102128811B (en) | Optical module and system for liquid sample | |
| US11692931B2 (en) | Concentration measurement device | |
| TWI294963B (en) | ||
| CN206147657U (en) | Thin Optical Fingerprint Sensor | |
| US7342662B2 (en) | Sample analyzer | |
| TWI792666B (en) | Measuring urine sugar concentration device | |
| CN116124712A (en) | Device capable of measuring urine sugar concentration | |
| KR100781968B1 (en) | Non-dispersive Infrared Gas Concentration Measurement Device with Adjustable Light Path Length | |
| CN100570331C (en) | Microchip inspection device and components thereof | |
| US20040075827A1 (en) | Method and apparatus for measuring the refractive index of at least two samples | |
| US11650150B2 (en) | Prism for measuring liquid concentration | |
| US11879888B2 (en) | Glycosuria measurement device | |
| TWI551269B (en) | Portable analytical device and system | |
| CN217359603U (en) | Probe type liquid concentration measuring device | |
| CN107796731A (en) | Liquid concentration detection device | |
| US20230236115A1 (en) | Optical absorption spectrometer | |
| US7298485B2 (en) | Method of and a device for measuring optical absorption characteristics of a sample | |
| CN102121899B (en) | Surface Plasmon Resonance Sensor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |