CN117181334A - Reagent bottle clamp and sample adding system - Google Patents

Abstract

This application discloses a reagent bottle clamp and a sample adding system. The reagent bottle clamp includes a clamp body, a clamping arm and a limiting member. The clamp body has an accommodating cavity and is connected to the accommodating cavity for reagent bottles. In and out of the first opening of the accommodating cavity, the clamping arm includes a hinged end, a free end and an extrusion part. The clamping arm is rotationally connected to the clamp body through the hinged end. The extrusion part squeezes or squeezes as the clamping arm rotates relative to the clamp body. The reagent bottle located in the holding chamber is released. The limiter is connected to the main body of the clip. The limiter is used to limit the rotational angular stroke of the clamping arm relative to the main body of the clip to limit the degree of squeezing of the reagent bottle by the extrusion part. In the embodiment of the present application, a limiter is provided to limit the rotational angular stroke of the clamping arm relative to the clamp body, so that each time the reagent bottle is squeezed through the extrusion part of the clamping arm, the degree of squeezing of the reagent bottle is reduced. The fixation is controllable, which in turn helps achieve quantitative dosing of substances in reagent bottles.

Description

Reagent bottle holder and sample loading system

Technical field

The application belongs to the technical field of blood sample detection, and specifically relates to a reagent bottle clamp and a sample adding system.

Background technique

In the blood sample testing process, it is usually necessary to thoroughly mix the collected blood sample and auxiliary agents such as buffer in a reagent bottle, and then add the mixed blood sample to the test card for further blood sample testing. In the existing technology, users usually directly squeeze the reagent bottle to add blood samples, which makes it difficult to achieve quantitative adding effects.

Contents of the invention

This application aims to provide a reagent bottle clamp and sample adding system to achieve the purpose of quantitatively adding samples to reagent bottles.

In order to solve the above technical problems, this application is implemented as follows:

In the first aspect, the embodiment of the present application proposes a reagent bottle clamp, including:

The clamp body has an accommodation cavity in the clamp body, and a first opening connected with the accommodation cavity for reagent bottles to enter and exit the accommodation cavity;

The clamping arm includes a hinged end, a free end and an extrusion part. The clamping arm is rotationally connected to the clamp body through the hinged end. The extrusion part squeezes or releases the position in the accommodation cavity as the clamping arm rotates relative to the clamp body. reagent bottles in;

The limiter is connected to the main body of the clip. The limiter is used to limit the rotation angle stroke of the clamp arm relative to the main body of the clip, so as to limit the degree of squeezing of the reagent bottle by the extrusion part.

In a second aspect, embodiments of the present application also provide a sample adding system, including:

a reagent bottle, which includes a mixing chamber and a second opening connected with the mixing chamber;

The catheter includes a blood collection end and a sample addition end that are connected to each other, and the blood collection end is embedded into the mixing chamber from the second opening; and,

Like the reagent bottle clamp shown in the first aspect, the reagent bottle clamp is used to squeeze the reagent bottle so that the sample in the reagent bottle is squeezed out from the sample adding end.

The reagent bottle clamp provided by the embodiment of the present application includes a clamp body, a clamping arm and a limiting member. The clamp body has an accommodation cavity, and a first opening connected with the accommodation cavity for reagent bottles to enter and exit the accommodation cavity. The clamping arm includes a hinged end, a free end and an extrusion part. The clamping arm is rotationally connected to the clamp body through the hinged end. The extrusion part squeezes or releases the reagent bottle located in the accommodation cavity as the clamping arm rotates relative to the clamp body. , the limiter is connected to the main body of the clip, and the limiter is used to limit the rotational angular stroke of the clamping arm relative to the main body of the clip, so as to limit the degree of squeezing of the reagent bottle by the extrusion part. In the embodiment of the present application, a limiter is provided to limit the rotational angular stroke of the clamping arm relative to the clamp body, so that each time the reagent bottle is squeezed through the extrusion part of the clamping arm, the degree of squeezing of the reagent bottle is reduced. The fixation is controllable, which in turn helps achieve quantitative dosing of substances in reagent bottles.

Additional aspects and advantages of the application will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the application.

Description of the drawings

The above and/or additional aspects and advantages of the present application will become apparent and readily understood from the description of the embodiments in conjunction with the following drawings, in which:

Figure 1 is a schematic three-dimensional structural diagram of a reagent bottle clamp provided by an embodiment of the present application;

Figure 2 is one of the schematic cross-sectional views of the reagent bottle clamp and the reagent bottle when the limiter is rotationally connected to the clamp body;

Figure 3 is the second schematic cross-sectional view of the reagent bottle clamp and the reagent bottle when the limiter is rotationally connected to the clamp body;

Figure 4 is the third schematic cross-sectional view of the reagent bottle clamp and the reagent bottle when the stopper is rotationally connected to the clamp body;

Figure 5 is one of the schematic cross-sectional views of the reagent bottle clamp and the reagent bottle when the limiter and the clamp body are rotated and connected through a linear motion mechanism;

Figure 6 is the second schematic cross-sectional view of the reagent bottle clamp and the reagent bottle when the limiter and the clamp body are rotated and connected through a linear motion mechanism;

Figure 7 is the third schematic cross-sectional view of the reagent bottle clamp and the reagent bottle when the limiter and the clamp body are rotated and connected through a linear motion mechanism;

Figure 8 is a schematic diagram of the assembly structure of the stopper and the main body of the clip when the linear motion mechanism is a screw mechanism;

Figure 9 is a schematic cross-sectional view of the reagent bottle clamp and the reagent bottle when the elastic member is a torsion spring;

Figure 10 is a schematic diagram of the exploded structure of the reagent bottle, conduit and end cap.

Reference signs: 100-reagent bottle clamp, 110-clamp body, 111-accommodation cavity, 112-first opening, 120-clamping arm, 121-hinge end, 122-free end, 123-squeezing part, 130 -Limiting piece, 131-linear motion mechanism, 132-screw, 133-nut, 134-bearing, 140-torsion spring, 210-reagent bottle, 211-mixing chamber, 212-second opening, 220-conduit, 221 -Blood collection end, 222-sample adding end, 230-end cap, 240-connection plate.

Detailed ways

The embodiments of the present application will be described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the drawings are exemplary and are only used to explain the present application and cannot be understood as limiting the present application. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of this application.

The terms "first" and "second" features in the description and claims of this application may include one or more of these features, either explicitly or implicitly. In the description of this application, unless otherwise stated, "plurality" means two or more. In addition, "and/or" in the description and claims indicates at least one of the connected objects, and the character "/" generally indicates that the related objects are in an "or" relationship.

In the description of this application, it needs to be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", " "Back", "Left", "Right", "Vertical", "Horizontal", "Top", "Bottom", "Inside", "Outside", "Clockwise", "Counterclockwise", "Axis" The orientation or positional relationship indicated by "radial direction", "circumferential direction", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply the device or device referred to. Elements must have a specific orientation, be constructed and operate in a specific orientation and therefore are not to be construed as limitations on the application.

In the description of this application, it should be noted that, unless otherwise clearly stated and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense. For example, it can be a fixed connection or a detachable connection. Connection, or integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be an internal connection between two components. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood on a case-by-case basis.

As shown in Figures 1 to 7, a reagent bottle clamp 100 according to some embodiments of the present application includes:

The clip body 110 has an accommodating cavity 111 in the clamp body 110, and a first opening 112 connected with the accommodating cavity 111 for the reagent bottle 210 to enter and exit the accommodating cavity 111;

Clamping arm 120. The clamping arm 120 includes a hinged end 121, a free end 122 and a pressing part 123. The clamping arm 120 is rotationally connected to the clamp body 110 through the hinged end 121. The pressing part 123 follows the clamping arm 120 relative to the clamp body. 110 rotates to squeeze or release the reagent bottle 210 located in the accommodation cavity 111;

The limiter 130 is connected to the clamp body 110 . The limiter 130 is used to limit the rotation angle stroke of the clamp arm 120 relative to the clamp body 110 to limit the degree of squeezing of the reagent bottle 210 by the extrusion part 123 . .

The reagent bottle clamp 100 provided in the embodiment of the present application can be used to clamp and squeeze the reagent bottle 210 to squeeze out the substance in the reagent bottle 210 . In some possible implementations, the substance in the reagent bottle 210 can be a blood sample, or a liquid after the blood sample is fully mixed with an auxiliary reagent, where the auxiliary reagent can be a buffer, an anticoagulant or a fluorescent agent, etc.; In other possible implementations, the substances in the reagent bottle 210 can also be other types of samples or simple reagents, etc., and no examples are given here. To simplify the description, in the following embodiments, the substance in the reagent bottle 210 is a blood sample mixed with an auxiliary reagent (which may be directly referred to as a blood sample in the following).

The clip body 110 can be a structure with a certain strength, and has an accommodating cavity 111 inside. The accommodating cavity 111 is connected to the external space through the first opening 112. In this way, the reagent bottle 210 can be inserted into the container through the first opening 112. in cavity 111.

A clamping arm 120 is rotatably connected to the clamp body 110 . Specifically, the clamping arm 120 includes a hinged end 121 , a free end 122 and a pressing part 123 . The hinged end 121 is connected to the clamp body 110 so that the clamping arm 120 The entire body can be rotated relative to the clip body 110 . The free end 122 may be an operable end. For example, the user can contact the free end 122 and exert force on the free end 122 to drive the clamping arm 120 to rotate around the hinged end 121 .

In some examples, the extruding part 123 may have a convex structure. During the rotation of the clamping arm 120 , the extruding part 123 may enter or exit the accommodating cavity 111 . When the extruding part 123 exits the accommodating cavity 111 When the reagent bottle 210 is located in the accommodating cavity 111, it can be separated from each other; when the extruding part 123 enters the accommodating cavity 111, it can contact and squeeze the reagent bottle 210 located in the accommodating cavity 111. The reagent bottle 210 is deformed, the internal volume is reduced, and the blood sample inside is squeezed out.

Generally speaking, the clamping arms 120 can be arranged in pairs. For example, the number of the clamping arms 120 is two. The user can apply force on the free ends 122 of the two clamping arms 120 at the same time, so that the two clamping arms 120 can The squeezing part 123 squeezes the reagent bottle 210 at the same time. Of course, in some possible implementations, the clamping arm 120 may also be provided on one side of the clip body 110 , and a fixed arm may be provided on the opposite side of the clip body 110 to the side where the clamping arm 120 is located, and the fixed arm may be fixedly provided. On the clamp body 110 , the user can apply force on the clamping arm 120 and the fixed arm at the same time, so that the clamping arm 120 rotates around the clamp body 110 , thereby causing the extrusion part 123 to squeeze the reagent bottle 210 .

A limiting member 130 is provided on the clip body 110 , and the limiting member 130 can be used to limit the rotational angular travel of the clamping arm 120 relative to the clip body 110 . It is easy to understand that in the process of the squeezing part 123 from contacting to squeezing the reagent bottle 210, as the clamping arm 120 rotates, the squeezing part 123 may be in a state of gradually deepening the squeezing degree of the reagent bottle 210. , that is, the rotation angle of the clamping arm 120 is related to the degree of squeezing of the reagent bottle 210 by the extrusion part 123. In this embodiment, the rotation angle stroke of the clamping arm 120 can be limited by the limiting member 130. The degree of squeezing of the reagent bottle 210 by the squeezing part 123 is limited.

Taking some examples, the limiter 130 can be fixed on the clamp body 110, the clamping arm 120 rotates under the driving of the user, the extrusion part 123 first contacts and then squeezes the reagent bottle 210, and the blood sample is squeezed out from the reagent bottle 210. , when the clamping arm 120 rotates to a certain angle, it contacts the limiting member 130. At this time, the limiting member 130 can limit the further movement of the clamping arm 120. The clamping arm 120 reaches the maximum rotation angle stroke, and the extruding part 123 is The squeezing degree of the reagent bottle 210 also reaches the maximum. It can be seen that due to the existence of the limiter 130, when the user operates the clamping arm 120 to rotate, from the beginning to exert force on the clamping arm 120 until the clamping arm 120 reaches the maximum rotation angle stroke, the squeezing part 123 aligns with the reagent bottle 210 The degree of squeezing can be considered as fixed, and the corresponding blood sample squeezed out from the reagent bottle 210 can also be considered as quantitative.

Of course, in some other feasible implementations, the position of the limiting member 130 can be adjusted. When the limiting member 130 is in different positions, the clamping arm 120 can contact the limiting member 130 at different rotation angles. , and further rotational movement is restricted by the limiting member 130. The specific structural implementation will be described in detail below.

The reagent bottle clamp 100 provided by the embodiment of the present application includes a clamp body 110, a clamping arm 120 and a limiting member 130. The clamp body 110 has an accommodating cavity 111 and is connected to the accommodating cavity 111 for the entry and exit of the reagent bottle 210. The first opening 112 of the accommodation cavity 111, the clamping arm 120 includes a hinged end 121, a free end 122 and an extrusion part 123. The clamping arm 120 is rotationally connected to the clamp body 110 through the hinged end 121, and the extrusion part 123 follows the clamping The arm 120 rotates relative to the clamp body 110 to squeeze or release the reagent bottle 210 located in the accommodating cavity 111. The limiting member 130 is connected to the clamp body 110. The limiting member 130 is used to limit the movement of the clamping arm 120 relative to the clamp body 110. The rotation angle stroke is used to limit the degree of squeezing of the reagent bottle 210 by the squeezing part 123. The embodiment of the present application limits the rotational angular stroke of the clamping arm 120 relative to the clamp body 110 by providing a limiter 130, so that each time the reagent bottle 210 is squeezed through the extrusion part 123 of the clamping arm 120, the reagent bottle 210 is squeezed. The squeezing degree of the reagent bottle 210 is fixed and controllable, thereby helping to achieve quantitative addition of the substance in the reagent bottle 210 .

The number of accommodating cavities 111 in the clip body 110 is one or more. In some possible implementations, the number of accommodating cavities 111 can be set to multiple, and one reagent bottle 210 can be placed in each accommodating cavity 111 , that is, the accommodating cavities 111 and the reagent bottles 210 can have a corresponding number in number. relation. The plurality of accommodation cavities 111 may be independent of each other, or may be connected to each other, as long as each accommodation cavity 111 can relatively independently accommodate the reagent bottle 210 .

Combined with some application scenarios, in order to improve the analysis efficiency of blood samples, users may need to operate multiple reagent bottles 210 at the same time. If multiple receiving chambers 111 are provided in a single clip body 110, a corresponding number of reagent bottles 210 can be accommodated. By operating the clamping arm 120 at one time, quantitative sampling from multiple reagent bottles 210 can be achieved.

In combination with other application scenarios, referring to Figures 2, 5 and 9, the shapes of the reagent bottles 210 may be different. In order to enable the clip body 110 to adapt to the reagent bottles 210 of different shapes, the at least two accommodation cavities 111 can be The shapes are set to be different, thereby increasing the applicable range of the reagent bottle clamp 100 .

In some possible implementations, the different shapes of the accommodation chamber 111 can also realize fool-proof designs for reagent bottles 210 of different shapes, so as to avoid affecting the quantification due to the reagent bottle clamp 100 misaligned or reversed. Sampling effect.

In order to enable the squeezing part 123 to effectively squeeze the reagent bottles 210 present in each accommodation cavity 111 when the user operates the clamping arm 120, in some embodiments, the number of the squeezing parts 123 may be multiple, The plurality of extruding parts 123 correspond to the plurality of accommodating cavities 111 one-to-one, so that the reagent bottle 210 in each accommodating cavity 111 can be reliably extruded through the corresponding extruding part 123 .

In some possible implementations, at least two pressing portions 123 have different shapes. Taking the extrusion part 123 as a convex structure on the clamping arm 120 as an example, the extrusion part 123 has different shapes, which may be different degrees of convexity or different curvatures of the convex surface, etc.

In some application scenarios, the shape of each accommodation cavity 111 can be the same, and the shape of the reagent bottles 210 that can be accommodated is also fixed. At this time, if the clamping arm 120 moves at a certain angle until it contacts the stopper 130, different shapes of The degree of squeezing of the corresponding reagent bottles 210 by the squeezing part 123 may be different, so that the amounts of blood samples taken out from different reagent bottles 210 are also different. It can be seen that by arranging the extruding parts 123 of different shapes, the sampling requirements of different amounts of blood samples can be met.

In other application scenarios, the shapes of at least two accommodating cavities 111 may be different to accommodate reagent bottles 210 of different shapes. If the shape of each extruding part 123 is kept the same, the clamping arm 120 may move to a certain extent. At different angles, the amount of blood sample taken out by different reagent bottles 210 is different. However, by reasonably setting the shape of each extrusion part 123, the shape of each extrusion part 123 is different, and the clamping arm 120 can also be moved at a certain angle. , the amount of blood samples taken out from reagent bottles 210 of different shapes is the same.

As shown above, the number of clamping arms 120 may be one or more. As shown in FIGS. 1 to 7 , in some preferred embodiments, the number of clamping arms 120 may be two. Two The clamping arms 120 are arranged correspondingly. When the user operates the reagent bottle clamp 100, the user can apply pressure on the free ends 122 of the two clamping arms 120 at the same time. The two clamping arms 120 can symmetrically squeeze both sides of the reagent bottle 210. pressure, effectively preventing the reagent bottle 210 from tilting during the operation, thereby ensuring the stability of the sampling process.

In some embodiments, each clamping arm 120 is connected to the clip body 110 through an elastic member (not shown in the figure). When the elastic member is in a released state, the extruding part 123 releases the clamp body 110 located in the accommodating cavity 111 . Reagent bottle 210.

Combined with some examples, the elastic member can be a torsion spring or an elastic piece, etc. The elastic member may have a released state, that is, the state of the elastic member when the user does not exert force on the reagent bottle clamp 100 . Corresponding to the release state, when the user exerts force on the clamping arm 120, the elastic member will deform and be in a deformed state.

When the elastic member is in the released state, the extruding part 123 can release the reagent bottle 210 located in the accommodating cavity 111. In some examples, the clip body 110 is provided with an opening communicating with the accommodating cavity 111. When the user clamps When the holding arm 120 exerts force, the squeezing part 123 can move from the opening to the accommodating cavity 111 to squeeze the reagent bottle 210. When the user releases the holding arm 120, under the action of the rebound force of the elastic member, The pressing part 123 can leave the accommodating cavity 111, thereby releasing the reagent bottle 210 located in the accommodating cavity 111.

In some embodiments, as shown in FIG. 9 , the hinged ends 121 of the two clamping arms 120 are each provided with a torsion spring 140 , the first end of the torsion spring 140 is connected to the clip body 110 , and the second end of the torsion spring 140 is connected to the clip body 110 . The hinged ends 121 of the clamping arms 120 are connected.

Of course, in some feasible implementations, even if the elastic member is in a released state, the pressing part 123 may also be located in the accommodation cavity 111, for example, may be in slight contact with the reagent bottle 210, and may exert static friction on the reagent bottle 210. The fixation effect is achieved without causing the blood sample to drip due to excessive squeezing of the reagent bottle 210.

In some embodiments, as shown in FIGS. 2 to 7 , the distance between the hinged end 121 and the free end 122 of the clamping arm 120 is greater than the distance between the hinged end 121 and the pressing portion 123 .

It is easy to understand that the clamping arm 120 can be considered as a lever with the hinged end 121 as the rotation center, the free end 122 can receive the user's driving force, and the squeezing portion 123 will receive the resistance provided by the reagent bottle 210 . The distance between the hinged end 121 and the free end 122 is greater than the distance between the hinged end 121 and the extrusion part 123. In a normal scenario, the moment arm corresponding to the driving force will be larger than the moment arm corresponding to the resistance. In this way, the user can A smaller force is used to drive the reagent bottle clamp 100 to squeeze the reagent bottle 210 to complete the blood sample sampling, thereby achieving a labor-saving effect.

In some preferred embodiments, the free end 122 and the extruding portion 123 are located on the same side of the hinged end 121 , which can make the overall arrangement of the reagent bottle clamp 100 more compact and reduce the overall size of the reagent bottle clamp 100 .

As shown above, the limiting member 130 may be fixed on the clip body 110 , or may be movably connected to the clip body 110 . When the limiter 130 is fixedly connected to the clip body 110, different quantitative requirements can be achieved by simply replacing the limiter 130 with different widths. When the stopper 130 is movably connected to the clip body 110, the stopper 130 moves relative to the clip body 110 to change the rotation angle. In this way, the amount of blood sample taken can be adjusted, and the functions of the reagent bottle clamp 100 are enriched. .

The following is an example of a structure in which the limiting member 130 is movably connected to the clip body 110 .

Optionally, as shown in FIGS. 2 to 4 , the limiter 130 is rotationally connected to the clip body 110 , and the limiter 130 has a surface with a changing outer diameter, so that when the limiter 130 rotates, the limiter 130 and the clamp body 110 can be adjusted. The distance of the clamping arm 120 in the thickness direction of the clamping arm 120 .

In some examples, the shape of the limiting member 130 may be an ellipse or an approximately elliptical shape, such that the limiting member 130 has a surface with varying outer diameters. With reference to FIGS. 2 to 4 , the limiter 130 is defined to be located in the middle of the two left and right clamping arms 120 . When the limiter 130 rotates, the length in the left-right direction changes due to changes in the outer diameter. When the length of the limiter 130 in the left-right direction is larger, the gap between the limiter 130 and the clamping arm 120 is shorter, and the clamping arm 120 can contact the limiter 130 by rotating at a smaller angle; conversely, , when the length of the limiter 130 in the left and right direction is small, the gap between the limiter 130 and the clamping arm 120 is longer, and the clamping arm 120 needs to rotate at a larger angle to contact the limiter 130 . That is to say, by rotating the limiter 130, the rotation angle stroke of the clamping arm 120 can be adjusted, thereby adjusting the degree of squeezing of the reagent bottle 210 by the extruding part 123, thereby adjusting the amount of blood sample taken.

Of course, in practical applications, the surface of the limiting member 130 may also be discontinuous. For example, there may be multiple groups of arcuate surfaces arranged in pairs, and the distances between different groups of arcuate surfaces to the rotation center of the limiting member 130 are different. In this way, , it is also possible to cause the length of the left and right direction to change when the limiting member 130 rotates, thereby adjusting the rotation angle stroke of the clamping arm 120 .

In some feasible implementations, the limiting member 130 and the clip body 110 can be connected through a rotating pair with a relatively high friction coefficient, so that the limiting member 130 can maintain a certain distance from the clip body 110 at various angular positions. The fixing strength prevents the limiting member 130 from rotating when the user operates the clamping arm 120 . In other possible implementations, the limiting member 130 and the clip body 110 may also be rotationally connected through a ratchet or other structures.

Optionally, as shown in FIGS. 5 to 7 , the limiter 130 is movably connected to the clip body 110 through a linear motion mechanism 131 , and the linear motion mechanism 131 is used to adjust the limiter 130 in the length extension direction of the clamp arm 120 . s position.

In some examples, the linear motion mechanism 131 can be a screw mechanism, or a positioning hole and a positioning rod whose position can be adjusted in the length direction, and the contact surface between the two can have a certain elasticity or a high friction coefficient, so that The positioning rod can be fixed at multiple depth positions of the positioning hole, thereby adjusting the linear distance between the limiter 130 and the clip body 110 . Of course, in some feasible implementations, the limiter 130 can also be simply connected to the clip body 110 through screws. When the limiter 130 is rotated, the limiter 130 will generate a linear displacement relative to the clip body 110 .

Referring to the examples of FIGS. 5 to 7 , the limiter 130 may be located in the middle of the clamping arms 120 on the left and right sides. The clamping arms 120 rotate at a certain angle around the hinged end 121 . The farther the clamping arm 120 is from the hinged end 121 The greater the linear displacement produced by the position. Assume that in a certain state, the extension direction from the hinged end 121 to the free end 122 of the clamping arm 120 is consistent with the linear movement direction of the limiter 130. At this time, when the limiter 130 moves to any position, it is in line with the clamping The distance between arms 120 is equal. However, when the clamping arm 120 rotates, at the same angle of rotation, the distance moved by the position near the free end 122 is greater than the distance moved by the position near the hinged end 121 . Correspondingly, the limiter 130 moves in a straight line. The closer the limiter 130 is to the free end 122 , the smaller the rotation angle stroke of the clamping arm 120 is. The holding arm 120 contacts the limiting member 130 at a larger rotation angle. It can be seen that by adjusting the position of the limiter 130 based on the linear motion mechanism 131, the rotation angle stroke of the clamping arm 120 can be adjusted, thereby adjusting the squeezing degree of the squeezing part 123 and the reagent bottle 210, so as to adjust the blood sample. The effect of dosage.

Of course, the above is a principle explanation of the adjustment of the blood sample taking amount of the reagent bottle clamp 100 based on the linear motion mechanism 131. In practical applications, the shape of the clamping arm 120, and the distance between the clamping arm 120 and the stopper 130 The relative orientation relationship of can be adjusted as needed, and no examples will be given here.

As shown above, in some embodiments, multiple accommodating cavities 111 may be provided in the clip body 110 , and these accommodating cavities 111 are defined in sequential steps in the width direction of the clip body 110 . Such a configuration makes the clip body 110 And the clamping arm 120 may have a larger width. As some feasible implementations, the limiting member 130 can be designed as an elongated structure so as to reliably contact the clamping arm 120 and thereby reliably limit the rotational angular stroke of the clamping arm 120 .

However, the clamping arms 120 are disposed on the left and right sides of the limiting member 130, which may also limit the rotational movement of the slender structure of the limiting member 130. In order to overcome the above possible problems, as shown in Figure 8, in some cases In the embodiment, the linear motion mechanism 131 is a screw mechanism. The screw mechanism includes a screw rod 132 and a nut 133. The screw rod 132 is fixedly connected to the clip body 110. The nut 133 is rotationally connected to the limiter 130 and is relatively fixed in the axial direction. .

The nut 133 is rotationally connected to the limiting member 130 and is relatively fixed in the axial direction. The nut 133 and the limiting member 130 can be connected through a bearing 134 . In a specific example, the nut 133 may have a manual adjustment part located above and a rotating connection part located below. The outer surface of the rotating connection part is connected to the limiting member 130 through the bearing 134. After adjusting the position of the limiting member 130 During adjustment, the user can rotate the nut 133, and the rotational motion of the nut 133 relative to the screw rod 132 is converted into a linear motion along the circumferential direction of the screw. Since the nut 133 and the limiter 130 are relatively fixed in the axial direction, they can drive the limiter. The member 130 produces linear motion. At the same time, due to the rotational connection between the nut 133 and the limiting member 130, the rotation of the nut 133 does not cause the rotation of the limiting member 130, and then adapts to the clamping arm 120 to form a rotation limit for the limiting member 130. Scenes. Of course, in practical applications, the nut 133 and the limiting member 130 can also be rotationally connected and axially relatively fixed through other connection forms, and examples are not given here.

In some feasible implementations, an external gear (not shown in the figure) can be further provided on the nut 133, and an indicator disk (not shown in the figure) can be rotated on the limiting member 130. The relationship between the indicator disk and the external gear is Knead each other, and by reasonably adjusting the transmission ratio of both meshing parties, the indicator plate can indicate the position of the nut 133, and the position of the nut 133 will affect the position of the limiter 130 and the rotation angle stroke of the clamping arm 120, thereby affecting the reagent Bottle clamp 100 blood sample sampling volume. Through calibration tests or theoretical calculations, the corresponding indication value on the indication plate can be set to the sampling volume of the blood sample. In this way, the user can determine the adjustment amount of the nut 133 by observing the indication on the indication plate, thereby realizing the adjustment of each blood sample. Precise adjustment of sampling volume.

The embodiment of the present application also provides a sampling system, including a reagent bottle 210 and the above-mentioned reagent bottle clamp 100.

In some embodiments, as shown in Figures 1 to 10, the sampling system may specifically include:

Reagent bottle 210. The reagent bottle 210 includes a mixing chamber 211 and a second opening 212 connected with the mixing chamber 211;

Conduit 220. Conduit 220 includes a blood collection end 221 and a sample addition end 222 that are connected to each other. The blood collection end 221 is embedded into the mixing chamber 211 from the second opening 212;

As well as the above-mentioned reagent bottle clamp 100, the reagent bottle clamp 100 is used to squeeze the reagent bottle 210 so that the sample in the reagent bottle 210 is squeezed out from the sample adding end 222.

As shown in Figure 10, the reagent bottle 210 and the catheter 220 can be provided in a matching manner. The blood collection end 221 of the catheter 220 can adopt a capillary structure to collect blood samples through capillary action. After the catheter 220 completes the collection of blood samples, the sampling end 222 can be extended into the mixing chamber 211 from the second opening 212, and the reagent bottle 210 and the catheter 220 can be combined with each other. At this time, the mixing chamber 211 is connected to the mixing chamber 211 through the blood collection end 221. external connectivity.

The mixing chamber 211 can be pre-injected with auxiliary agents such as buffers. After the catheter 220 is inserted into the reagent bottle 210, the blood sample can be mixed with the buffer behind the mixing chamber 211. The mixed blood sample (can be referred to as the blood sample) is in Status to be sampled. At this time, the reagent bottle 210 can be inserted into the accommodation cavity 111 from the first opening 112 of the reagent bottle clamp 100, and the user drives the clamping arm 120 to squeeze the blood sample in the reagent bottle 210 from the sample end 222. out. Since the reagent bottle clamp 100 is provided with the limiting member 130, the rotation angle stroke of the clamping arm 120 can be limited, thereby achieving quantitative sampling of blood samples.

Of course, in practical applications, the sample in the reagent bottle 210 may be a blood sample or other types of samples, such as water sample or urine sample.

As shown in Figure 10, in some embodiments, the blood sample to be sampled may need to be stored or transported. In order to prevent the blood sample from being accidentally poured out or contaminated during the period, the catheter 220 can be equipped with an end cap 230, and the end cap 230 can be Detach the blood collection end 221 connected to the catheter 220. In this way, both ends of the conduit 220 are sealed by the reagent bottle 210 and the end cap 230 respectively, thereby can isolate the blood sample from the external environment; when sampling is required, the end cap 230 can be removed from the conduit 220 .

As mentioned in the above embodiment, the number of accommodating cavities 111 in the clip body 110 can be multiple. Correspondingly, the number of reagent bottles 210 and conduits 220 can also be multiple, and there is a corresponding relationship in quantity. , multiple conduits 220 can be fixed through connecting plates 240 .

It is easy to understand that the sampling system is a system including the reagent bottle clamp 100 in the above embodiment. The embodiment of the reagent bottle clamp 100 can also be used with the embodiment of the sampling system, and achieves corresponding technical effects, which will not be discussed here. Repeat instructions.

In the description of this specification, reference to the description of the terms "one embodiment," "some embodiments," "illustrative embodiments," "examples," "specific examples," or "some examples" or the like is intended to be in conjunction with the implementation. An example or example describes a specific feature, structure, material, or characteristic that is included in at least one embodiment or example of the present application. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

Although the embodiments of the present application have been shown and described, those of ordinary skill in the art will understand that various changes, modifications, substitutions and modifications can be made to these embodiments without departing from the principles and purposes of the present application. The scope of the application is defined by the claims and their equivalents.

Claims (10)

1. A reagent bottle clamp, characterized in that it includes: Clip body (110), the clip body (110) has an accommodating cavity (111), and is connected to the accommodating cavity (111) for the reagent bottle (210) to enter and exit the accommodating cavity (111) The first opening (112); Clamping arm (120), the clamping arm (120) includes a hinged end (121), a free end (122) and a pressing part (123), the clamping arm (120) passes through the hinged end (121) ) is rotationally connected to the clip body (110), and the extrusion portion (123) squeezes or releases the position in the accommodation cavity (123) as the clamp arm (120) rotates relative to the clip body (110). The reagent bottle (210) in 111); Limiting member (130), the limiting member (130) is connected to the clip body (110), and the limiting member (130) is used to limit the clamping arm (120) relative to the clip body. (110) to limit the degree of squeezing of the reagent bottle (210) by the squeezing part (123). 2. The reagent bottle clamp according to claim 1, characterized in that the limiting member (130) is movably connected to the clamp main body (110), and the limiting member (130) is opposite to the clamp main body. (110) moves to change the rotation angle stroke. 3. The reagent bottle clamp according to claim 2, characterized in that the limiting member (130) is movably connected to the clamp body (110) through a linear motion mechanism (131), and the linear motion mechanism (131) ) is used to adjust the position of the limiting member (130) in the length extension direction of the clamping arm (120). 4. According to claim 3, characterized in that the linear motion mechanism (131) is a screw mechanism, and the screw mechanism includes a screw (132) and a nut (133), and the screw (132) ) is fixedly connected to the clip body (110), and the nut (133) is rotationally connected to the limiting member (130) and is relatively fixed in the axial direction. 5. The reagent bottle clamp according to claim 2, characterized in that the limiter (130) is rotationally connected to the clamp body (110), and the limiter (130) has a surface with a changing outer diameter. , to adjust the distance between the limiting member (130) and the clamping arm (120) in the thickness direction of the clamping arm (120) when the limiting member (130) rotates. 6. The reagent bottle clamp according to claim 1, characterized in that the distance between the hinge end (121) and the free end (122) is greater than the distance between the hinge end (121) and the extrusion end. distance between parts (123). 7. The reagent bottle clamp according to claim 1, characterized in that the number of the accommodation cavities (111) is multiple, and at least two of the accommodation cavities (111) have different shapes to adapt to The reagent bottles (210) of different shapes. 8. The reagent bottle clamp according to claim 7, characterized in that the number of the squeeze parts (123) is multiple, and the plurality of squeeze parts (123) and the plurality of accommodation cavities (123) are 111) One-to-one correspondence, at least two of the pressing parts (123) have different shapes. 9. The reagent bottle clamp according to claim 1, characterized in that the number of the clamping arms (120) is two, and the two clamping arms (120) are symmetrically arranged; each clamping arm (120) are all connected to the clip body (110) through an elastic member. When the elastic member is in a released state, the extrusion part (123) releases the reagent located in the accommodation cavity (111). bottle(210). 10. A sample adding system, characterized in that it includes: A reagent bottle (210), the reagent bottle (210) includes a mixing chamber (211) and a second opening (212) connected to the mixing chamber (211); Conduit (220). The conduit (220) includes a blood collection end (221) and a sample addition end (222) that are connected to each other. The blood collection end (221) is embedded into the mixing chamber from the second opening (212). (211); and, The reagent bottle clamp (100) according to any one of claims 1 to 9, the reagent bottle clamp (100) is used to squeeze the reagent bottle (210) so that the reagent bottle (210) is The sample is extruded from the loading end (222).