CN117883057B - Blood pressure measuring method, system and storage medium combining ascending method and descending method - Google Patents
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Abstract
Description
技术领域Technical Field
本发明涉及无创血压测量技术领域,更具体的说是涉及一种上升法与下降法结合的血压测量方法、系统及存储介质。The present invention relates to the technical field of non-invasive blood pressure measurement, and more specifically to a blood pressure measurement method, system and storage medium combining an ascending method and a descending method.
背景技术Background Art
高血压的出现,可能会引发心血管类或肾脏类疾病。高盐多油的饮食习惯与不规律的生活作息等使得越来越多的人受到高血压的困扰,高血压问题也因此被越来越多的人关注到。The occurrence of high blood pressure may lead to cardiovascular or kidney diseases. High-salt and high-fat diets and irregular lifestyles have caused more and more people to suffer from high blood pressure, and the problem of high blood pressure has therefore attracted more and more attention.
高血压作为一种慢性疾病,其本身对身体的影响并不明显,所以很多患者难以察觉是否自身血压有异常,但一旦因此而引发心血管类或肾脏类疾病将造成较为严重的后果。所以血压作为身体健康监测的一项重要指标经常被要求测量或实时地监测。已经有相关研究表明,对患者血压的日常监测与管理对于预防高血压及由其引发疾病是行之有效的。然而目前缺少一套简便易行且能实时测量血压的解决方案。As a chronic disease, hypertension itself does not have a significant impact on the body, so many patients find it difficult to detect whether their blood pressure is abnormal. However, once cardiovascular or kidney diseases are caused, it will cause more serious consequences. Therefore, blood pressure is often required to be measured or monitored in real time as an important indicator of physical health monitoring. Relevant studies have shown that daily monitoring and management of patients' blood pressure is effective in preventing hypertension and diseases caused by it. However, there is currently a lack of a simple and easy solution that can measure blood pressure in real time.
目前的血压检测方法,容易受到各种各样噪声的影响,因此,如何提供一种避免噪声影响,并且简单有效的血压测量方法是本领域技术人员亟需研究的。The current blood pressure detection method is easily affected by various noises. Therefore, how to provide a simple and effective blood pressure measurement method that avoids the influence of noise is urgently needed to be studied by those skilled in the art.
发明内容Summary of the invention
有鉴于此,本发明提供了一种上升法与下降法结合的血压测量方法、系统及存储介质,通过上升法和下降法相互补偿的方式,并结合数字信号处理技术,解决背景技术中存在的问题。In view of this, the present invention provides a blood pressure measurement method, system and storage medium that combine the ascending method and the descending method, which solves the problems existing in the background technology by compensating each other by the ascending method and the descending method and combining digital signal processing technology.
为了实现上述目的,本发明采用如下技术方案:In order to achieve the above object, the present invention adopts the following technical solution:
一种上升法与下降法结合的血压测量方法,包括以下步骤:A blood pressure measurement method combining an ascending method and a descending method comprises the following steps:
在袖带加压过程中,获取压力增大过程中的第一脉搏信号集合;During the cuff pressurization process, obtaining a first pulse signal set during the pressure increase process;
在袖带释压过程中,获取压力减小过程中的第二脉搏信号集合;During the cuff pressure release process, obtaining a second pulse signal set during the pressure reduction process;
分别对第一脉搏信号集合和第二脉搏信号集合进行去噪预处理;Performing denoising preprocessing on the first pulse signal set and the second pulse signal set respectively;
提取第一脉搏信号集合和第二脉搏信号集合的数字信号特征向量,并提取每个数字信号特征向量对应的脉搏传导时间;Extracting digital signal feature vectors of the first pulse signal set and the second pulse signal set, and extracting the pulse conduction time corresponding to each digital signal feature vector;
将数字信号特征向量与脉搏传导时间的映射关系输入到长短期记忆神经网络模型中;The mapping relationship between the digital signal feature vector and the pulse conduction time is input into the long short-term memory neural network model;
长短期记忆神经网络模型根据映射关系识别出是否低于正常血压、是否高于正常血压。The long short-term memory neural network model identifies whether the blood pressure is lower than normal or higher than normal based on the mapping relationship.
可选的,还包括根据长短期记忆神经网络模型的输出结果绘制测量血压过程中的血压图像。Optionally, the method also includes drawing a blood pressure image during the blood pressure measurement process based on the output results of the long short-term memory neural network model.
可选的,第一脉搏信号集合和第二脉搏信号集合的获取过程如下:根据预设的时间间隔,对脉搏信号进行周期性的采集,得到多个周期性的信号,将多个周期性的信号进行按时间顺序排列,得到脉搏信号集合。Optionally, the acquisition process of the first pulse signal set and the second pulse signal set is as follows: according to a preset time interval, the pulse signal is periodically collected to obtain a plurality of periodic signals, and the plurality of periodic signals are arranged in chronological order to obtain a pulse signal set.
可选的,血压图像的绘制过程为:采用自适应阈值法对数据的转折点进行筛选,进而得到每个周期的主波波谷和主波波峰,截取各个主波波谷至主波波峰,作为一个周期图像。Optionally, the process of drawing the blood pressure image is: using an adaptive threshold method to screen the turning points of the data, and then obtaining the main wave trough and the main wave peak of each cycle, and intercepting each main wave trough to the main wave peak as a cycle image.
可选的,分别对第一脉搏信号集合和第二脉搏信号集合进行去噪预处理,具体为:采用二阶带通滤波器和基于小波滤波的信号平滑算法依次处理脉搏信号,二阶带通滤波器用于对噪声的特征进行截断去噪,基于小波滤波的信号平滑算法用于对噪声进行分离去噪。Optionally, the first pulse signal set and the second pulse signal set are pre-processed for denoising respectively, specifically: the pulse signals are processed in sequence using a second-order bandpass filter and a signal smoothing algorithm based on wavelet filtering, the second-order bandpass filter is used to truncate and denoise the characteristics of the noise, and the signal smoothing algorithm based on wavelet filtering is used to separate and denoise the noise.
可选的,脉搏传导时间为血液从心脏流动到测量点所需时间,利用多路不同信号之间特征计算传导时间。Optionally, the pulse conduction time is the time required for blood to flow from the heart to the measurement point, and the conduction time is calculated using characteristics between multiple different signals.
一种上升法与下降法结合的血压测量系统,包括以下步骤:A blood pressure measurement system combining an ascending method and a descending method comprises the following steps:
第一信号获取模块:用于在袖带加压过程中,获取压力增大过程中的第一脉搏信号集合;A first signal acquisition module: used for acquiring a first pulse signal set in a process of increasing pressure during the cuff pressurization process;
第二信号获取模块:用于在袖带释压过程中,获取压力减小过程中的第二脉搏信号集合;A second signal acquisition module: used for acquiring a second pulse signal set in a pressure reduction process during the cuff pressure release process;
去噪处理模块:用于分别对第一脉搏信号集合和第二脉搏信号集合进行去噪预处理;De-noising processing module: used for performing de-noising pre-processing on the first pulse signal set and the second pulse signal set respectively;
特征信号提取模块:用于提取第一脉搏信号集合和第二脉搏信号集合的数字信号特征向量,并提取每个数字信号特征向量对应的脉搏传导时间;A characteristic signal extraction module: used to extract digital signal characteristic vectors of the first pulse signal set and the second pulse signal set, and to extract the pulse conduction time corresponding to each digital signal characteristic vector;
长短期记忆神经网络模型输入模块:用于将数字信号特征向量与脉搏传导时间的映射关系输入到长短期记忆神经网络模型中;Long short-term memory neural network model input module: used to input the mapping relationship between the digital signal feature vector and the pulse conduction time into the long short-term memory neural network model;
长短期记忆神经网络模型处理模块:用于根据映射关系识别出是否低于正常血压、是否高于正常血压。Long short-term memory neural network model processing module: used to identify whether the blood pressure is lower than normal or higher than normal based on the mapping relationship.
可选的,还包括图像绘制模块:用于根据长短期记忆神经网络模型的输出结果绘制测量血压过程中的血压图像。Optionally, it also includes an image drawing module: used to draw a blood pressure image during the blood pressure measurement process according to the output results of the long short-term memory neural network model.
一种计算机存储介质,所述计算机存储介质上存储有计算机程序,所述计算机程序被处理器执行时实现任意一项所述的一种上升法与下降法结合的血压测量方法的步骤。A computer storage medium having a computer program stored thereon, wherein when the computer program is executed by a processor, the steps of any one of the blood pressure measurement methods combining an ascending method with a descending method are implemented.
经由上述的技术方案可知,与现有技术相比,本发明提供了一种上升法与下降法结合的血压测量方法、系统及存储介质,其中,上升法血压测量具有快速、舒适的优点,但抗干扰能力差,当测量过程中有干扰或者测量对象有心律失常时结果误差比较大。下降法采用平台降压具有抗干扰能力强的优点,但测量时间长、舒适性差。相对于现有的只有其中一种的测量方法,两种方法相结合后对于正常测量只需要进行上升法测量,保留了快速、舒适、准确的优点,当上升受干扰或测量对象心律失常时会继续采用下降法测量,提高测量的准确性。It can be known from the above technical solutions that, compared with the prior art, the present invention provides a blood pressure measurement method, system and storage medium combining the ascending method and the descending method, wherein the ascending method blood pressure measurement has the advantages of being fast and comfortable, but has poor anti-interference ability. When there is interference during the measurement process or the measured object has arrhythmia, the result error is relatively large. The descending method uses platform pressure reduction and has the advantage of strong anti-interference ability, but the measurement time is long and the comfort is poor. Compared with the existing measurement method that only has one of them, after the two methods are combined, only the ascending method measurement is required for normal measurement, which retains the advantages of being fast, comfortable and accurate. When the ascending method is interfered or the measured object has arrhythmia, the descending method measurement will continue to be used to improve the accuracy of the measurement.
附图说明BRIEF DESCRIPTION OF THE DRAWINGS
为了更清楚地说明本发明实施例或现有技术中的技术方案,下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据提供的附图获得其他的附图。In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.
图1为本发明的流程示意图;Fig. 1 is a schematic diagram of the process of the present invention;
图2为本发明的正常血压图像示意图;FIG2 is a schematic diagram of a normal blood pressure image of the present invention;
图3为本发明的异常血压图像示意图。FIG. 3 is a schematic diagram of an abnormal blood pressure image according to the present invention.
具体实施方式DETAILED DESCRIPTION
下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
本发明实施例公开了一种上升法与下降法结合的血压测量方法,如图1所示,包括以下步骤:The embodiment of the present invention discloses a blood pressure measurement method combining an ascending method and a descending method, as shown in FIG1 , comprising the following steps:
S1:在袖带加压过程中,获取压力增大过程中的第一脉搏信号集合;S1: during the cuff pressurization process, obtaining a first pulse signal set during the pressure increase process;
S2:在袖带释压过程中,获取压力减小过程中的第二脉搏信号集合;S2: during the cuff pressure release process, obtaining a second pulse signal set during the pressure reduction process;
S3:分别对第一脉搏信号集合和第二脉搏信号集合进行去噪预处理;S3: performing denoising preprocessing on the first pulse signal set and the second pulse signal set respectively;
S4:提取第一脉搏信号集合和第二脉搏信号集合的数字信号特征向量,并提取每个数字信号特征向量对应的脉搏传导时间;S4: extracting digital signal feature vectors of the first pulse signal set and the second pulse signal set, and extracting the pulse transmission time corresponding to each digital signal feature vector;
S5:将数字信号特征向量与脉搏传导时间的映射关系输入到长短期记忆神经网络模型中;S5: inputting the mapping relationship between the digital signal feature vector and the pulse conduction time into the long short-term memory neural network model;
S6:长短期记忆神经网络模型根据映射关系识别出是否低于正常血压、是否高于正常血压。S6: The long short-term memory neural network model identifies whether the blood pressure is lower than normal or higher than normal based on the mapping relationship.
进一步的,本实施例中还包括根据长短期记忆神经网络模型的输出结果绘制测量血压过程中的血压图像。Furthermore, this embodiment also includes drawing a blood pressure image during the blood pressure measurement process according to the output results of the long short-term memory neural network model.
更进一步的,血压图像的绘制过程为:采用自适应阈值法对数据的转折点进行筛选,进而得到每个周期的主波波谷和主波波峰,截取各个主波波谷至主波波峰,作为一个周期图像。Furthermore, the blood pressure image drawing process is: using the adaptive threshold method to screen the turning points of the data, and then obtaining the main wave trough and the main wave peak of each cycle, and intercepting each main wave trough to the main wave peak as a cycle image.
进一步的,在S1和S2中,第一脉搏信号集合和第二脉搏信号集合的获取过程如下:根据预设的时间间隔,对脉搏信号进行周期性的采集,得到多个周期性的信号,将多个周期性的信号进行按时间顺序排列,得到脉搏信号集合。Furthermore, in S1 and S2, the acquisition process of the first pulse signal set and the second pulse signal set is as follows: according to a preset time interval, the pulse signal is periodically collected to obtain multiple periodic signals, and the multiple periodic signals are arranged in chronological order to obtain a pulse signal set.
进一步的,在S3中,分别对第一脉搏信号集合和第二脉搏信号集合进行去噪预处理,具体为:采用二阶带通滤波器和基于小波滤波的信号平滑算法依次处理脉搏信号,二阶带通滤波器用于对噪声的特征进行截断去噪,基于小波滤波的信号平滑算法用于对噪声进行分离去噪。Furthermore, in S3, the first pulse signal set and the second pulse signal set are subjected to denoising preprocessing respectively, specifically: the pulse signals are processed in sequence using a second-order bandpass filter and a signal smoothing algorithm based on wavelet filtering, the second-order bandpass filter is used to truncate and denoise the characteristics of the noise, and the signal smoothing algorithm based on wavelet filtering is used to separate and denoise the noise.
进一步的,在S5中,脉搏传导时间为血液从心脏流动到测量点所需时间,利用多路不同信号之间特征计算传导时间。本实施例选择从心脏位置的ECG和指端位置脉搏两路信号提取PATro和PATrb两种脉搏传导时间。Further, in S5, the pulse transmission time is the time required for blood to flow from the heart to the measurement point, and the transmission time is calculated using the characteristics between multiple different signals. This embodiment selects to extract two types of pulse transmission time, PATro and PATrb, from two signals, ECG at the heart position and pulse at the fingertip position.
进一步的,血压的形成主要是由血液容量、外周阻力、血管壁弹性这三个因素共同决定。对于同一个个体,在短期内外周阻力、血管壁弹性都不会有明显的变化,可以认为是一个定值,这种情况下血压的大小就主要由血容量决定了。而PPG信号反映的就是血管内血容量的周期变化,对于多路PPG信号,或PPG信号与ECG信号配合的多路信号,可以计算出脉搏传播速度以构建PPG信号与血压之间的关系模型。在本实施例中选用长短期记忆神经网络模型完成脉搏信号与血压关系的构建。Furthermore, the formation of blood pressure is mainly determined by three factors: blood volume, peripheral resistance, and vascular wall elasticity. For the same individual, there will be no obvious changes in peripheral resistance and vascular wall elasticity in the short term, which can be considered as a constant value. In this case, the size of blood pressure is mainly determined by blood volume. The PPG signal reflects the periodic changes in blood volume in the blood vessels. For multiple PPG signals, or multiple signals of PPG signals and ECG signals, the pulse propagation velocity can be calculated to construct a relationship model between the PPG signal and blood pressure. In this embodiment, a long short-term memory neural network model is used to complete the construction of the relationship between the pulse signal and blood pressure.
具体的,在本实施例中,首先,手臂戴好袖带,设备开始充气,使得袖带压以约10mmHg/s匀速上升。检测血压袖带内的气体压力变化并提取的压力脉搏波,当检测到的脉搏波幅值可以形成典型的包络线并且幅值间隔均匀的情况下采用系数法得到血压值,结束测量。如图2所示。Specifically, in this embodiment, first, the arm is fitted with a cuff, and the device starts to inflate, so that the cuff pressure rises at a constant speed of about 10 mmHg/s. The gas pressure change in the blood pressure cuff is detected and the pressure pulse wave is extracted. When the detected pulse wave amplitude can form a typical envelope and the amplitude interval is uniform, the coefficient method is used to obtain the blood pressure value, and the measurement is ended. As shown in Figure 2.
如果检测到的脉搏波幅值形成非典型包络线或者幅值间隔不均匀(如图3),说明血压测量过程中受到干扰或者测量对象有心律失常现象。当检测到动脉血流被阻断时采用平台法降压继续测量。If the detected pulse wave amplitude forms an atypical envelope or the amplitude interval is uneven (as shown in Figure 3), it means that the blood pressure measurement process is disturbed or the measured object has arrhythmia. When it is detected that the arterial blood flow is blocked, the plateau method is used to reduce the blood pressure and continue the measurement.
本实施例还公开了一种上升法与下降法结合的血压测量系统,包括以下步骤:This embodiment also discloses a blood pressure measurement system combining the ascending method and the descending method, comprising the following steps:
第一信号获取模块:用于在袖带加压过程中,获取压力增大过程中的第一脉搏信号集合;A first signal acquisition module: used for acquiring a first pulse signal set in a process of increasing pressure during the cuff pressurization process;
第二信号获取模块:用于在袖带释压过程中,获取压力减小过程中的第二脉搏信号集合;A second signal acquisition module: used for acquiring a second pulse signal set in a pressure reduction process during the cuff pressure release process;
去噪处理模块:用于分别对第一脉搏信号集合和第二脉搏信号集合进行去噪预处理;De-noising processing module: used for performing de-noising pre-processing on the first pulse signal set and the second pulse signal set respectively;
特征信号提取模块:用于提取第一脉搏信号集合和第二脉搏信号集合的数字信号特征向量,并提取每个数字信号特征向量对应的脉搏传导时间;A characteristic signal extraction module: used to extract digital signal characteristic vectors of the first pulse signal set and the second pulse signal set, and to extract the pulse conduction time corresponding to each digital signal characteristic vector;
长短期记忆神经网络模型输入模块:用于将数字信号特征向量与脉搏传导时间的映射关系输入到长短期记忆神经网络模型中;Long short-term memory neural network model input module: used to input the mapping relationship between the digital signal feature vector and the pulse conduction time into the long short-term memory neural network model;
长短期记忆神经网络模型处理模块:用于根据映射关系识别出是否低于正常血压、是否高于正常血压。Long short-term memory neural network model processing module: used to identify whether the blood pressure is lower than normal or higher than normal based on the mapping relationship.
进一步的,还包括图像绘制模块:用于根据长短期记忆神经网络模型的输出结果绘制测量血压过程中的血压图像。Furthermore, it also includes an image drawing module: used to draw a blood pressure image during the blood pressure measurement process according to the output results of the long short-term memory neural network model.
本实施例还公开了一种计算机存储介质,所述计算机存储介质上存储有计算机程序,所述计算机程序被处理器执行时实现任意一项所述的一种上升法与下降法结合的血压测量方法的步骤。This embodiment further discloses a computer storage medium having a computer program stored thereon. When the computer program is executed by a processor, the steps of any one of the blood pressure measurement methods combining the ascending method with the descending method are implemented.
本说明书中各个实施例采用递进的方式描述,每个实施例重点说明的都是与其他实施例的不同之处,各个实施例之间相同相似部分互相参见即可。对于实施例公开的装置而言,由于其与实施例公开的方法相对应,所以描述的比较简单,相关之处参见方法部分说明即可。In this specification, each embodiment is described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the embodiments can be referred to each other. For the device disclosed in the embodiment, since it corresponds to the method disclosed in the embodiment, the description is relatively simple, and the relevant parts can be referred to the method part.
对所公开的实施例的上述说明,使本领域专业技术人员能够实现或使用本发明。对这些实施例的多种修改对本领域的专业技术人员来说将是显而易见的,本文中所定义的一般原理可以在不脱离本发明的精神或范围的情况下,在其它实施例中实现。因此,本发明将不会被限制于本文所示的这些实施例,而是要符合与本文所公开的原理和新颖特点相一致的最宽的范围。The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.
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