CN118078373A

CN118078373A - Aneurysm embolism system

Info

Publication number: CN118078373A
Application number: CN202410508855.9A
Authority: CN
Inventors: 荆洪娟; 宋维康; 黄嘉平
Original assignee: Hangzhou Yike Medical Technology Co ltd
Current assignee: Hangzhou Yike Medical Technology Co ltd
Priority date: 2024-04-26
Filing date: 2024-04-26
Publication date: 2024-05-28
Anticipated expiration: 2044-04-26
Also published as: CN118078373B

Abstract

The invention discloses an aneurysm embolism system, comprising: a delivery tube for guiding to the interior of the aneurysm; the spring ring embolism device comprises a spring ring pushing rod and a spring ring, wherein the spring ring pushing rod is detachably connected with the spring ring; the plugging device comprises a plugging pushing rod and a continuous rod-shaped plugging object, wherein the plugging pushing rod is detachably connected with the plugging object, the plugging object can be deformed in a torsion way after being released into an aneurysm and is formed into an anchoring part, an action part and a plugging part, and the action part is connected between the anchoring part and the plugging part and is used for abutting the anchoring part on the top of the aneurysm and the plugging part on the neck of the aneurysm; wherein the occlusion device is configured such that, upon advanced release of the occlusion through the delivery tube into the interior of the aneurysm and back out of the delivery tube, the spring coil embolic device is capable of independently releasing the spring coil from the same delivery tube to fill the interior of the aneurysm. The invention allows the spring coil and the plug to be transported through the same delivery tube.

Description

Aneurysm embolism system

Technical Field

The invention relates to the technical field of medical appliances, in particular to an aneurysm embolism system.

Background

Aneurysms, which are an abnormal expansion of locally weakened areas of the vessel wall, have the potential to rupture and bleed. In recent years, coil embolic therapy has evolved as an effective means of treating aneurysms, particularly in intracranial aneurysms. The principle of coil embolic therapy is to fill coils in an aneurysm to reduce or block blood flow in the aneurysm, thereby promoting thrombosis, which ultimately results in stagnation of blood flow in the aneurysm, effectively reducing the risk of rupture of the aneurysm.

The Chinese patent CN114869389A discloses a technical scheme for treating aneurysms by using spring coils for embolism, in the embolism process, an intratumoral stent is firstly conveyed into the aneurysms through a conveying pipe, the top mesh structure of a stent body can be attached to the wall of the aneurysms by virtue of the softness of braiding wires, yielding holes in the bottom center of the stent body are all positioned at the neck of the aneurysms, then microcatheters for conveying the spring coils can smoothly enter the aneurysms through the yielding holes in the bottom center of the stent body, the spring coils are released by the microcatheters to fill the aneurysms, after the filling of the spring coils is completed, the microcatheters for conveying the spring coils are released, the positions of the intratumoral stent are adjusted by the conveying pipe, the intratumoral stent is released after the position of the intratumoral stent is adjusted properly, and finally the conveying pipe for conveying the intratumoral stent is removed.

CN114869389A is used for assisting the spring ring to plug through the intratumoral stent, so that the spring ring is effectively prevented from falling off to the aneurysm-carrying artery, and meanwhile, the occupation effect of the intratumoral spring ring can effectively prevent the intratumoral stent from moving to the top of the aneurysm, so that the stability and the reliability of the plug effect are ensured. However, this embolic mechanism requires that the stent be released after the coil is completely released to prevent displacement of the stent toward the apex of the aneurysm, which not only increases the complexity of the surgeon's surgical procedure, but also requires the use of two separate delivery tubes for separately delivering the stent and coil, which adds to some degree to the difficulty and cost of the procedure.

Disclosure of Invention

The invention aims to solve the technical problem that the prior art has the defects, and provides an aneurysm embolism system.

According to the present invention there is provided an aneurysm embolization system comprising:

A delivery tube for guiding to the interior of the aneurysm;

the spring ring embolism device comprises a spring ring pushing rod and a spring ring, wherein the spring ring pushing rod is detachably connected with the spring ring;

The plugging device comprises a plugging pushing rod and a continuous rod-shaped plugging object, wherein the plugging pushing rod is detachably connected with the plugging object, the plugging object can be deformed in a torsion way after being released into an aneurysm and is formed into an anchoring part, an action part and a plugging part, and the action part is connected between the anchoring part and the plugging part and is used for abutting the anchoring part on the top of the aneurysm and the plugging part on the neck of the aneurysm;

Wherein the occlusion device is configured such that, upon advanced release of the occlusion through the delivery tube into the interior of the aneurysm and back out of the delivery tube, the spring coil embolic device is capable of independently releasing the spring coil from the same delivery tube to fill the interior of the aneurysm.

Further, the anchoring portion forms a disk shape and closely fits the top of the aneurysm under the action of the action portion.

Further, the anchoring portion is torsionally deformed into a C-shaped disc by the distal section of the occlusion.

Further, the action part is an arc-shaped rod, and the action part is connected between the molding end of the anchoring part and the molding start end of the plugging part.

Further, the action part is two arc rods, one of the two arc rods is connected between the molding end of the anchoring part and the molding start end of the plugging part, and the other arc rod is connected at the molding start end of the anchoring part and is abutted with the plugging part.

Further, the two arc-shaped rods are arranged in a crossing way.

Further, the blocking part forms a disc shape and is tightly attached to the neck of the aneurysm under the action of the acting part.

Further, the occlusion is torsionally deformed from the proximal section of the occlusion into a conical disc.

Further, a via hole for the delivery tube to extend into the aneurysm is arranged at the proximal end of the blocking part.

Further, the via hole is formed for a central ending opening of the plugging part.

Compared with the prior art, once the occlusion substance is deployed inside the aneurysm, the occlusion substance can automatically twist and change the shape to occlude the neck of the aneurysm and effectively fix the occlusion substance, so that the spring ring and the occlusion substance can be allowed to carry out conveying operation through the same conveying pipe.

Drawings

The invention will be more fully understood and its attendant advantages and features will be more readily understood by reference to the following detailed description, taken in conjunction with the accompanying drawings.

FIG. 1 is a schematic view of a spring coil plug device according to an embodiment of the present invention.

Fig. 2 is a schematic structural view of an occlusion embolic device according to a first embodiment of the present invention.

Fig. 3 is a schematic illustration of the structure of the closure of fig. 2.

Fig. 4 is a schematic structural view of the stopper pushing rod of fig. 2.

Fig. 5-7 are schematic views showing the co-operation of the occlusion plug device and the delivery tube according to the first embodiment of the present invention.

Fig. 8 is a schematic diagram of the structure of an aneurysm filled with coils according to an embodiment of the present invention.

Fig. 9 is a schematic structural diagram of a closure in accordance with a second embodiment of the present invention.

In the accompanying drawings: 100 is a conveying pipe; 200 is a spring coil plug device, 201 is a spring coil push rod, and 202 is a spring coil; 300 is a plugging material plug device, 301 is a plugging material pushing rod, 302 is a plugging material, 303 is an anchoring part, 304 is an acting part, 305 is a plugging part, 306 is a via hole, 307 is a jacket, 308 is a clamping piece, 309 is a clamping cambered surface, 310 is a clamping hole, 311 is a convex column; 400 is an aneurysm.

It should be noted that the drawings are for illustrating the invention and are not to be construed as limiting the invention. Note that the drawings representing structures may not be drawn to scale. Also, in the drawings, the same or similar elements are denoted by the same or similar reference numerals.

Detailed Description

In order that the invention may be more readily understood, a detailed description of the invention is provided below along with specific embodiments and accompanying figures.

The terms "proximal" and "distal" in the sense of the present invention should be understood as meaning, viewed from the direction of the attending physician, the term "proximal" referring to the end proximal to the attending physician, i.e. corresponding to the "left end" referred to with reference to the accompanying drawings, and the term "distal" referring to the end distal to the attending physician, i.e. corresponding to the "right end" referred to with reference to the accompanying drawings. Similarly, "proximal segment" refers to a segment or a particular region proximal to the attending physician, and "distal segment" refers to a segment or a particular region distal to the attending physician.

Embodiment one: as shown in fig. 1 to 8, the aneurysm embolization system of the present embodiment comprises a delivery tube 100, a coil embolization device 200 and an occlusion embolization device 300. The delivery tube 100 is an elongated conduit for guiding into the interior of the aneurysm for delivering the coil embolic device 200 and the occlusion embolic device 300. The coil embolic device 200 includes a coil push rod 201 and a coil 202, the coil 202 being a coiled wire designed to fill the lumen of the aneurysm and prevent further damage caused by blood flow, the coil push rod 201 being configured to push the coil 202 into the aneurysm and release it in place, the distal end of the coil push rod 201 and the proximal end of the coil 202 being in a detachable connection, either an electrolytic detachment or a conventional mechanical detachment, ensuring that the coil 202 is safely and accurately deployed in a predetermined position. The embolic device 300 is used to assist in the operation of the coil embolic device 200, preventing the displacement and drop of the coil 202 within an aneurysm, and the embolic device 300 comprises an embolic pusher rod 301 and a continuous rod-shaped occluding member 302, the distal end of the embolic pusher rod 301 being detachably connected to the proximal end of the occluding member 302.

The plug 302 is also a spiral wire but has a larger diameter than the coil 202. The blocking object 302 has shape memory property, after the blocking object 302 is released into an aneurysm, the blocking object 302 is automatically deformed in a twisting way and is formed into an anchoring portion 303, an acting portion 304 and a blocking portion 305, the acting portion 304 is connected between the anchoring portion 303 and the blocking portion 305, the anchoring portion 303 is abutted against the top of the aneurysm and the blocking portion 305 is abutted against the neck of the aneurysm, the anchoring portion 303 is designed to tightly abutted against the top of the aneurysm, a stable supporting effect is provided, the position of the blocking portion 305 in the aneurysm is ensured to be fixed, the acting portion 304 serves as an intermediate connecting link, smooth transition from the anchoring portion 303 to the blocking portion 305 is ensured, and the blocking portion 305 is designed to tightly abutted against the neck of the aneurysm, so that displacement and falling of the aneurysm inner spring ring 202 are effectively prevented. The structural nature of the occluding material 302 allows it to automatically twist and change shape once deployed inside an aneurysm to occlude the neck of the aneurysm and effectively secure, thus allowing the coil 202 and occluding material 302 to be delivered through the same delivery tube 100, and in particular the occluding device 300 is configured such that after the occluding material 302 is released into the aneurysm and withdrawn from the delivery tube 100, the coil embolic device 200 can independently release the coil 202 using the same delivery tube 100 to fill the interior of the aneurysm. I.e., the occlusion 302 is fully released within the aneurysm, the occlusion push rod 301 can be withdrawn back out of the delivery tube 100, allowing the coil push rod 201 to deliver the coil 202 through the delivery tube 100. The integrated conveying structure simplifies the operation flow, reduces the operation complexity of doctors in the operation and simultaneously reduces the medical cost.

The anchoring portion 303 forms a disc shape and is tightly attached to the top of the aneurysm under the action of the action portion 304, the blocking portion 305 forms a disc shape and is tightly attached to the neck of the aneurysm under the action of the action portion 304, and the action portion 304 deforms along with the size of the aneurysm so as to always abut the anchoring portion 303 and the blocking portion 305 against the top and the neck of the aneurysm. The anchor 303 is torsionally deformed from the distal section of the occluding component 302 into a C-shaped disc which not only provides a stable support point, but also minimizes unnecessary irritation of the top of the aneurysm and reduces the risk of potential complications by its C-shaped design. In addition, the disk-like structure of the anchor 303 can be fine-tuned according to the specific morphology of the aneurysm, ensuring a perfect match with the top of the aneurysm. The plugging portion 305 is formed by twisting and deforming a proximal end section of the plugging material 302 into a conical disc with a small proximal end and a large distal end so as to adapt to different sizes and shapes of the neck of the aneurysm, the stable fixation of the plugging material 302 is ensured, a via hole 306 for the spring coil 202 to extend into the aneurysm is formed at the proximal end of the plugging portion 305, the spring coil 202 can be ensured to effectively fill the cavity of the aneurysm, the via hole 306 is formed as a central ending opening of the plugging portion 305, and the center of the plugging portion 305 can automatically form the ending opening in the forming process. The action portion 304 is formed by twisting and deforming the middle section of the blocking object 302 into an arc-shaped rod, the arc-shaped rod is connected between the forming end of the anchoring portion 303 and the forming start end of the blocking portion 305, the arc-shaped rod is easy to adjust due to the design of the arc-shaped rod structure, the action portion 304 can be adaptively deformed according to the size and shape of an aneurysm, the flexibility ensures that the anchoring portion 303 and the blocking portion 305 can be tightly attached to the top and neck of the aneurysm all the time, and therefore a stable and effective blocking is provided. That is, the occluding component 302 is in a continuous rod-like structure in an undeployed state, and once deployed inside the aneurysm, can automatically twist and convert into a disc-shaped anchoring portion 303, an arc-shaped acting portion 304 and a disc-shaped occluding portion 305, and promote the occluding portion 305 to be tightly attached to the neck of the aneurysm, thereby effectively preventing the displacement and falling of the spring coil 202, thus not only ensuring the stability of the occluding effect, but also simplifying the delivery and accurate release process of the occluding component embolic device 300.

The distal end of the plugging material pushing rod 301 is connected with a self-expanding collet 307, the collet 307 is used for controlling the release of the plugging material 302, the collet 307 is detachably sleeved at the proximal end of the plugging material 302, when the conveying pipe 100 is retracted relative to the plugging material pushing rod 301 so that the collet 307 is exposed out of the conveying pipe 100, the collet 307 gradually expands and is separated from the proximal end of the plugging material 302 so that the plugging material 302 is released, at the moment, the conveying pipe 100 is advanced relative to the plugging material pushing rod 301 so that the collet 307 gradually contracts and can be reconnected with the proximal end of the plugging material 302 in the process of accommodating the collet 307 in the conveying pipe 100, and thus, even if the plugging material 302 is carelessly and completely released in operation, a doctor can still realize reconnection with the plugging material 302 by operating the conveying pipe 100 and the plugging material pushing rod 301 through a gradual tightening mechanism of the collet 307.

The collet 307 is designed as an annular structure and an annular sleeve with a tapered feature wherein the proximal end is smaller in diameter and the distal end is larger in diameter, which allows the collet 307 to provide a firm grip while facilitating the release of the closure 302. The proximal end of the collet 307 is a fixed end and is coupled to the distal end of the stopper pushing rod 301, and the distal end of the collet 307 is a free end and faces the proximal end of the stopper 302, so that when the delivery tube 100 moves relative to the stopper pushing rod 301, the distal end of the collet 307 switches between a radially expanded state and a radially contracted state to facilitate clamping and releasing the stopper 302.

The distal end of the collet 307 is circumferentially designed with a plurality of clamping members 308, and the clamping members 308 are in a clamping spherical state and have proper clamping force. The proximal end of the stopper 302 is designed to be spherical with a gripping curve 309 for use with the gripping member 308. When the collet 307 is contracted, the clamping member 308 is able to tightly abut the clamping camber 309, resulting in an effective clamping of the proximal end of the closure 302. This mechanism allows the operator to withdraw the occlusion 302 into the interior of the delivery tube 100 via the occlusion push rod 301 to facilitate the necessary adjustment or repositioning. In order to enhance the clamping force and facilitate the withdrawal operation of the closure 302 after reconnection, the collet 307 is provided with a plurality of deformable clamping holes 310, the proximal end of the closure 302 is correspondingly provided with lugs 311, these lugs 311 are located in the proximal direction of the clamping cambered surface 309, and during the contraction of the collet 307, the lugs 311 can be inserted into the clamping holes 310, thereby generating additional clamping force between the collet 307 and the proximal end of the closure 302, which not only helps to stabilize the closure 302, ensuring that it will not move during withdrawal, but also allows fine adjustment of the angle of the closure 302, making it more conforming to the shape of the neck of the aneurysm, so as to achieve an optimal closure effect. By this design, the collet 307 is not only able to effectively grip and secure the occluding material 302, but also to retract or otherwise maneuver when needed, and this flexible and robust gripping mechanism is critical to ensure the accuracy and safety of the aneurysm occlusion treatment.

In the aneurysm treatment operation, the device 300 for embolizing the occlusion substance, i.e. the pushing rod 301 for pushing the occlusion substance and the occlusion substance 302, are first placed in the delivery tube 100 together, the pushing rod 301 for pushing the occlusion substance and the occlusion substance 302 are pushed to the position of the target aneurysm 400 together by the delivery tube 100, as shown in fig. 5, and the occlusion substance 302 is pushed out from the delivery tube 100 by operating the pushing rod 301 for pushing the occlusion substance 302, so that the primary release of the occlusion substance 302 is realized. Once released, the occluding component 302 will automatically twist and deform to conform closely to the neck of the aneurysm 400 as shown in FIG. 6. If the position of the occluding component 302 needs to be fine-tuned, the position of the occluding component 302 can be fine-tuned by rotating the occluding component pushing rod 301 and utilizing the cooperation between the clamping holes 310 of the collet 307 and the posts 311 of the occluding component 302. Thereafter, the delivery tube 100 is retracted relative to the closure push rod 301 until the collet 307 is separated from the closure 302 after being exposed to the delivery tube 100 to completely release the closure 302 as shown in fig. 7. If the closure push rod 301 is withdrawn from the delivery tube 100, the closure push rod 301 may be repositioned by reversing the operation of the delivery tube 100 and closure push rod 301, i.e., advancing the delivery tube 100 relative to the closure push rod 301, in combination with the retraction of the closure push rod 301, by a gradual tightening mechanism of the collet 307. Finally, the coil embolic device 200, i.e., the coil push rod 201 and the coil 202, are placed together inside the delivery tube 100, and the delivery of the coil 202 into the aneurysm 400 is initiated through the proximal port 306 of the occluding material 302, and after the coil 202 completely fills the aneurysm 400, the coil push rod 201 and the delivery tube 100 are retracted. By using this combination, the aneurysm embolization system of the present embodiment is able to effectively occlude the aneurysm 400 as shown in fig. 8, reduce the risk of rupture, and promote thrombosis, ultimately achieving therapeutic objectives.

Embodiment two: unlike the first embodiment, as shown in fig. 9, the acting portion 304 of the present embodiment is two arc-shaped rods, the two arc-shaped rods are disposed in a crossing manner, one of the two arc-shaped rods is connected between the forming end of the anchoring portion 303 and the forming start end of the plugging portion 305, and the other arc-shaped rod is connected at the forming start end of the anchoring portion 303 and is closely abutted to the plugging portion 305. The two arc-shaped rods which are arranged in a crossing manner not only have stronger acting force, but also have excellent adjustability, and can be adaptively deformed according to the specific size and shape of the aneurysm, so that the anchoring portion 303 and the blocking portion 305 can be continuously and tightly attached to the top and neck of the aneurysm, and a safer and more effective treatment scheme is provided for patients.

Other structures of this embodiment are identical to those of the embodiment, and are not described herein.

It will be appreciated that although the invention has been described above in terms of preferred embodiments, the above embodiments are not intended to limit the invention. Many possible variations and modifications of the disclosed technology can be made by anyone skilled in the art without departing from the scope of the technology, or the technology can be modified to be equivalent. Therefore, any simple modification, equivalent variation and modification of the above embodiments according to the technical substance of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. An aneurysm embolization system, comprising:

a delivery tube (100) for guiding to the interior of the aneurysm (400);

The spring ring embolism device (200) comprises a spring ring pushing rod (201) and a spring ring (202), wherein the spring ring pushing rod (201) is detachably connected with the spring ring (202);

The occlusion plug device (300) comprises an occlusion push rod (301) and a continuous rod-shaped occlusion (302), wherein the occlusion push rod (301) is detachably connected with the occlusion (302), the occlusion (302) can be deformed in a torsion mode after being released into an aneurysm (400) and is formed into an anchoring portion (303), an acting portion (304) and an occlusion portion (305), the acting portion (304) is connected between the anchoring portion (303) and the occlusion portion (305) and is used for abutting the anchoring portion (303) on the top of the aneurysm (400) and the occlusion portion (305) on the neck of the aneurysm (400);

Wherein, the occlusion embolic device (300) is configured such that, after the occlusion (302) is released into the interior of the aneurysm (400) via the delivery tube (100) and withdrawn from the delivery tube (100), the coil embolic device (200) is capable of independently releasing the coil (202) to fill the interior of the aneurysm (400) using the same delivery tube (100).

2. The aneurysm embolization system of claim 1, wherein the anchoring portion (303) forms a disc shape and fits snugly against the top of the aneurysm (400) under the action of the action portion (304).

3. The aneurysm embolization system of claim 2, wherein the anchoring portion (303) is torsionally deformed into a C-shaped disc by a distal section of the occlusion (302).

4. The aneurysm embolization system of claim 2, wherein the active portion (304) is an arcuate rod, the active portion (304) being connected between the molding terminal end of the anchoring portion (303) and the molding starting end of the occlusion portion (305).

5. The aneurysm embolization system according to claim 2, wherein the action portion (304) is two arc-shaped rods, one of which is connected between the molding end of the anchoring portion (303) and the molding start end of the plugging portion (305), and the other of which is connected at the molding start end of the anchoring portion (303) and abuts against the plugging portion (305).

6. The aneurysm embolization system of claim 5, wherein two arcuate rods are disposed crosswise.

7. The aneurysm embolization system of claim 1, wherein the occlusion (305) forms a disc shape and fits snugly against the neck of the aneurysm (400) under the action of the action portion (304).

8. The aneurysm embolization system of claim 7, wherein the occlusion (305) is torsionally deformed from a proximal section of the occlusion (302) into a conical disc.

9. The aneurysm embolization system of claim 7, wherein the occlusion (305) is provided at a proximal end with a via (306) for the delivery tube (100) to extend into the aneurysm (400).

10. The aneurysm embolization system according to claim 9, wherein the via (306) is formed for a central ending of the occlusion (305).