CN118843248B - A heavy ion scanning beam transport vacuum chamber based on composite flange profiled wall - Google Patents
A heavy ion scanning beam transport vacuum chamber based on composite flange profiled wall Download PDFInfo
- Publication number
- CN118843248B CN118843248B CN202411032076.2A CN202411032076A CN118843248B CN 118843248 B CN118843248 B CN 118843248B CN 202411032076 A CN202411032076 A CN 202411032076A CN 118843248 B CN118843248 B CN 118843248B
- Authority
- CN
- China
- Prior art keywords
- wall
- vacuum chamber
- flange
- heavy ion
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002131 composite material Substances 0.000 title claims abstract description 18
- 238000003466 welding Methods 0.000 claims abstract description 19
- 238000013461 design Methods 0.000 claims abstract description 11
- 230000003014 reinforcing effect Effects 0.000 claims abstract description 5
- 239000002184 metal Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 238000009434 installation Methods 0.000 abstract description 9
- 230000005484 gravity Effects 0.000 abstract description 3
- 238000006073 displacement reaction Methods 0.000 abstract description 2
- 238000005259 measurement Methods 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 238000010884 ion-beam technique Methods 0.000 description 3
- 230000007547 defect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 102000006391 Ion Pumps Human genes 0.000 description 1
- 108010083687 Ion Pumps Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
- H05H7/14—Vacuum chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/10—Nuclear fusion reactors
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Particle Accelerators (AREA)
- Electron Sources, Ion Sources (AREA)
Abstract
本发明涉及一种基于复合法兰异型壁的重离子扫描束输运真空室，包括通道和围绕所述通道的真空室壁及快接端法兰；上述真空室壁上安装有较重的无位置精度的辅助设备和高精度测量仪器，重型辅助设备对真空室壁及安装法兰有很大的力矩，所以这些设备安装一侧采用薄壁及增强筋结构，以在保证室体刚度下并减重。安装测量仪器的真空室壁一侧的壁厚较厚并采用侧壁及法兰一体化加工，以减少形变。解决了以往在真空室壁上焊接法兰连接这些设备存在的焊接形变，引起辅助设备位移误差的问题。本发明所述的真空室通过结构设计补偿薄壁侧刚性，使得真空室整体有均衡的强度，能够达到360°重力各向同性安装位置上整体形变满足重离子扫描束流输运的精度要求。
The present invention relates to a heavy ion scanning beam transport vacuum chamber based on a composite flange profiled wall, comprising a channel, a vacuum chamber wall surrounding the channel and a quick-connect end flange; heavy auxiliary equipment without positional accuracy and high-precision measuring instruments are installed on the above-mentioned vacuum chamber wall. The heavy auxiliary equipment has a large torque on the vacuum chamber wall and the mounting flange, so a thin wall and reinforcing rib structure are used on the installation side of these equipment to ensure the rigidity of the chamber body and reduce the weight. The wall thickness of the vacuum chamber wall on the side where the measuring instrument is installed is relatively thick, and the side wall and flange are integrated to reduce deformation. The problem of welding deformation existing in the past when welding flanges on the vacuum chamber wall to connect these devices, causing displacement errors of auxiliary equipment, is solved. The vacuum chamber described in the present invention compensates for the thin-wall side rigidity through structural design, so that the vacuum chamber as a whole has balanced strength, and can achieve overall deformation at a 360° gravity isotropic installation position to meet the accuracy requirements of heavy ion scanning beam transport.
Description
Technical Field
The invention relates to the field of heavy ion treatment devices, in particular to a heavy ion scanning beam transport vacuum chamber based on a composite flange special-shaped wall.
Background
The ion beam generated by the medical heavy ion treatment device is transported in an ultra-high vacuum environment as much as possible so as to reduce the beam quality reduction and the beam target spot drift caused by an air section and ensure the beam quality. The general vacuum tube and the comprehensive deformation caused by welding flanges on the wall of the vacuum chamber reduce the installation precision of vacuum equipment and beam measuring instruments and increase the collimation difficulty during installation. For non-horizontal mounting positions, the gravity conditions to which the devices and instruments are subjected are different, and the deformation of the conventional vacuum tube is caused. A set of beam transport vacuum chamber with 360-degree isotropy of gravity and convenient installation of a high-precision measuring instrument is designed, and has great engineering significance for improving the defects and improving the beam quality of heavy ion cancer treatment.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a heavy ion scanning beam transport vacuum chamber based on a composite flange special-shaped wall, so as to solve the problem that in the prior art, auxiliary equipment is welded on the wall of the vacuum chamber through mounting pipes, and when the wall of the vacuum chamber is deformed, the displacement of the auxiliary equipment and the lower structural strength of the vacuum chamber manufactured by splicing a plurality of sections of linear pipelines are caused.
In order to achieve the above purpose, the technical scheme of the invention is as follows:
Heavy ion scanning beam transport vacuum chamber based on composite flange special-shaped wall;
The vacuum chamber comprises a transport beam vacuum space and a vacuum chamber wall surrounding the transport beam vacuum space, wherein a flange on the vacuum chamber wall is of an integrated flange design.
The vacuum chamber is characterized in that the wall of the vacuum chamber is designed as a whole, and the vacuum chamber is welded and connected into a whole through two first wall plates machined and a second wall plate manufactured through a sheet metal process.
The technical scheme is that the first wall plate is provided with an integrally machined window flange, the second wall plate is welded with a welding flange, the wall thickness of the first wall plate is a, and the wall thickness of the second wall plate is b, wherein a is larger than b.
The second wall plate is welded with the two first wall plates into a whole after the whole plate metal plate is bent.
The further technical scheme is that the second wallboard and the welding flange are welded with reinforcing ribs.
The further technical scheme is that the window flange is used for installing a measuring instrument for detecting beam current, the second wall plate is provided with a welding flange, and the welding flange is used for installing vacuum holding equipment.
Compared with the prior art, the invention has the following beneficial technical effects:
(1) The wall thickness of the vacuum chamber wall is divided into two groups for design, wherein the first wall plate is thicker than the second wall plate, auxiliary equipment with high measurement precision is arranged on the first wall plate, auxiliary equipment without beam measurement precision is arranged on the second wall plate, the second wall plate is provided with reinforcing ribs, so that the vacuum chamber wall has certain structural strength, the window flange is directly machined on the vacuum chamber wall through a machining center, the position of the window flange on the vacuum chamber wall can be accurately controlled, the auxiliary equipment and the instrument are arranged at the position of the window flange on the vacuum chamber wall, the auxiliary equipment and the instrument can be accurately arranged on the vacuum chamber wall, when the heavy ion scanning beam based on the special-shaped wall of the composite flange conveys the vacuum chamber to be in a vertical position or a 45-degree inclined position, the second wall plate can deform due to the fact that the wall thickness of the first wall is far greater than that of the second wall plate, the deformation on the second wall plate has weak influence on the first wall plate, and the accuracy of the installation position of the auxiliary equipment on the first wall plate is guaranteed. The window flange on the first wall plate cannot be subjected to position deviation due to any deformation, so that the positions of the auxiliary equipment after being installed are consistent all the time, and the normal operation of the medical heavy ion treatment device is ensured.
(2) The vacuum chamber is designed into a whole, replaces the traditional multi-section design or ladder barrel scheme, reduces the probability of leakage of the vacuum chamber, is convenient to install, and improves the structural strength. The vacuum chamber wall is formed by welding two first wall plates and a bent second wall plate, so that the condition that thin plates are mutually welded is avoided, the welding difficulty can be effectively reduced, and the sealing performance of the vacuum chamber wall is enhanced.
(3) The vacuum chamber wall adopts the design of different wall thicknesses, so that resonance in the operation process of the front-end scanning magnet can be effectively reduced, and the operation stability is improved.
(4) The window flange and the welding flange can be freely provided with various auxiliary equipment according to the requirement, so that the heavy ion scanning beam conveying vacuum chamber based on the special-shaped wall of the composite flange can be in modularized design, is flexible to use, and meets the requirements of various medical heavy ion treatment devices.
Drawings
Fig. 1 shows a schematic perspective view of a heavy ion scanning beam transport vacuum chamber based on a composite flange profiled wall in accordance with an embodiment of the invention.
Fig. 2 shows a top cross-sectional view of a heavy ion scanning beam transport vacuum chamber based on a composite flange profiled wall in accordance with an embodiment of the invention.
The drawing comprises a transport beam vacuum space 1, a vacuum chamber wall 2, a first wall plate 21, a second wall plate 22, a window flange 23, a welding flange 24.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the following more detailed description of the device according to the present invention is given with reference to the accompanying drawings and the detailed description. The advantages and features of the present invention will become more apparent from the following description. It should be noted that the drawings are in a very simplified form and are all to a non-precise scale, merely for the purpose of facilitating and clearly aiding in the description of embodiments of the invention. For a better understanding of the invention with objects, features and advantages, refer to the drawings. It should be understood that the structures, proportions, sizes, etc. shown in the drawings are for illustration purposes only and should not be construed as limiting the invention to the extent that any modifications, changes in the proportions, or adjustments of the sizes of structures, proportions, or otherwise, used in the practice of the invention, are included in the spirit and scope of the invention which is otherwise, without departing from the spirit or essential characteristics thereof.
Fig. 1 shows a schematic perspective view of a heavy ion scanning beam transport vacuum chamber based on a composite flange profiled wall in accordance with an embodiment of the invention. Fig. 2 shows a top cross-sectional view of a heavy ion scanning beam transport vacuum chamber based on a composite flange profiled wall in accordance with an embodiment of the invention. The invention discloses a heavy ion scanning beam transport vacuum chamber based on a composite flange special-shaped wall, which is shown in the combination of fig. 1 and 2.
The heavy ion scanning beam transport vacuum chamber based on the composite flange special-shaped wall comprises a transport beam vacuum space 1 and a vacuum chamber wall 2 surrounding the transport beam vacuum space 1. The vacuum chamber wall 2 is provided with auxiliary equipment without beam measurement precision requirements and a measuring instrument for beam detection at a high-precision installation position. The position precision of the measuring instrument for beam detection of the high-precision mounting position is +/-0.02 millimeter.
The ion beam must be transported in a vacuum environment to reduce the resistance of the ion beam during operation, and the heavy ion scanning beam transport vacuum chamber is installed in the medical heavy ion treatment device, and the interior of the heavy ion scanning beam transport vacuum chamber is in a vacuum state. Auxiliary equipment includes pneumatic valves, quick-closing valves, dry mechanical pumps, sputter ion pumps, vacuum gauges, and the like. The monitoring of the heavy ion scanning beam conveying vacuum chamber to obtain the running state and parameters can be completed through auxiliary equipment, and when the medical heavy ion treatment device fails, corresponding protection measures can be made through the auxiliary equipment.
The vacuum chamber wall 2 in the present application is of one piece design. The wall thickness in the vacuum chamber wall 2 is divided into two groups for design, so that the vacuum chamber wall 2 has two wall thicknesses with different thicknesses at the same time, and the vacuum chamber wall 2 can form a special-shaped wall structure. The vacuum chamber wall 2 is welded and connected into a whole through two machined first wall plates 21 and a sheet metal bent second wall plate 22.
The application is designed differently by two wall plates of the vacuum chamber wall 2. The first wall plate 21 is provided with an integrally machined window flange 23, auxiliary equipment is arranged on the window flange 23, a welding flange 24 is welded on the second wall plate 22, and vacuum maintaining equipment without beam measuring precision requirements is arranged on the welding flange 24. The wall thickness a of the first wall panel 21 is substantially greater than the wall thickness b of the second wall panel 22. The wall thickness a of the first wall panel 21 has a value of five times or more than the wall thickness b of the second wall panel 22.
The vacuum chamber is designed as a whole, replaces the traditional multi-section design or ladder barrel scheme, reduces the leakage probability of the vacuum chamber, is convenient to install, and improves the structural strength. The vacuum chamber wall is formed by welding two first wall plates 21 and a bent second wall plate 22, so that the condition that thin plates are mutually welded is avoided, the welding difficulty can be effectively reduced, and the tightness of the vacuum chamber wall 2 is enhanced. The second wall plate 22 and the welding flange 27 are welded with reinforcing ribs, so that the structural strength of the vacuum chamber wall 2 is further improved.
The two first wall plates 21 are welded together to form an L-shape. The second wall plate 22 is bent by metal plate to form an L shape. The first wall plate 21 and the second wall plate 22 are welded.
The vacuum chamber wall 2 in the present application includes a first wall plate 21 on the side where the high-precision beam measuring instrument is installed and a second wall plate 22 on the side where no auxiliary equipment for measuring the beam current is installed. The first wall plate 21 has a thicker wall thickness for mounting the beam measuring instrument with higher accuracy. The second wall plate 22 has a thinner wall thickness, and deformation of the device mounted on the thin wall does not affect the whole vacuum chamber wall 2, so that the influence on the whole deformation of the vacuum chamber wall 2 is reduced. The vacuum chamber wall 2 has certain structural strength, and meanwhile, the influence on the detection precision of auxiliary equipment is reduced.
The vacuum chamber wall 2 adopts the design of different wall thicknesses, so that resonance in the operation process of the front-end scanning magnet can be effectively reduced, and the operation stability is improved.
The window flange 23 is processed directly on the vacuum chamber wall 2 through a processing center, and the position of the window flange 23 on the vacuum chamber wall 2 can be accurately controlled. When the heavy ion scanning beam transportation vacuum chamber based on the composite flange special-shaped wall is in a vertical position or an inclined 45-degree position, the second wall plate 24 can deform due to the fact that the vacuum holding equipment with large installation weight and no beam measurement precision requirement is arranged, and the deformation on the second wall plate 22 has weak influence on the first wall plate 21 on the vacuum chamber wall because the wall thickness of the first wall plate 21 is far larger than that of the second wall plate 22, so that the deformation on the first wall plate 21 is small, and the accuracy of the installation position of auxiliary equipment on the first wall plate 21 is guaranteed. The window flange 23 on the first wall plate 21 cannot be deformed to shift in position, so that the positions of the auxiliary equipment after being installed are consistent all the time, and the normal operation of the medical heavy ion treatment device is ensured.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.
Claims (3)
1. The heavy ion scanning beam transport vacuum chamber based on the composite flange special-shaped wall is characterized by comprising a vacuum chamber wall (2) surrounding a transport beam vacuum space (1), wherein a flange on the vacuum chamber wall (2) is of an integrated flange design;
The vacuum chamber wall (2) is integrally designed, and is welded and connected into a whole through two machined first wall plates (21), a sheet metal process second wall plate (22) and a flange end plate;
the wall thickness of the first wall plate (21) is a, and the wall thickness of the second wall plate (22) is b, wherein a is larger than b;
the second wall plates (22) are welded with the two first wall plates (21) into a whole after the whole plate metal plate is bent.
2. The heavy ion scanning beam transport vacuum chamber based on the composite flange special-shaped wall according to claim 1, wherein the first wall plate (21) is provided with an integrally machined window flange (23), the window flange (23) is used for installing a measuring instrument for detecting beam current, the second wall plate (22) is provided with a welding flange (24), and the welding flange (24) is used for installing vacuum maintaining equipment.
3. The heavy ion scanning beam transport vacuum chamber based on composite flange profiled walls according to claim 2, wherein the second wall plate (22) and the welding flange (24) are welded with reinforcing ribs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411032076.2A CN118843248B (en) | 2024-07-30 | 2024-07-30 | A heavy ion scanning beam transport vacuum chamber based on composite flange profiled wall |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411032076.2A CN118843248B (en) | 2024-07-30 | 2024-07-30 | A heavy ion scanning beam transport vacuum chamber based on composite flange profiled wall |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN118843248A CN118843248A (en) | 2024-10-25 |
| CN118843248B true CN118843248B (en) | 2025-03-28 |
Family
ID=93143875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411032076.2A Active CN118843248B (en) | 2024-07-30 | 2024-07-30 | A heavy ion scanning beam transport vacuum chamber based on composite flange profiled wall |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN118843248B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115921899A (en) * | 2023-03-09 | 2023-04-07 | 中国科学院近代物理研究所 | A method of manufacturing a titanium alloy thin-walled ribbed extremely high vacuum chamber |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2488766A1 (en) * | 1980-08-18 | 1982-02-19 | IVANOV Andrei | Shielded irradiation electrons accelerator - has protection chamber with partition separating section with vacuum chamber window and scanner in other section |
| US5898179A (en) * | 1997-09-10 | 1999-04-27 | Orion Equipment, Inc. | Method and apparatus for controlling a workpiece in a vacuum chamber |
| WO2016051441A1 (en) * | 2014-09-29 | 2016-04-07 | 株式会社日立製作所 | Ion beam device and sample observation method |
| CN108969907B (en) * | 2018-07-05 | 2021-01-29 | 惠州离子科学研究中心 | Particle beam therapy head device for obtaining small beam spot |
| CN208657153U (en) * | 2018-07-11 | 2019-03-26 | 中广核达胜加速器技术有限公司 | Electron accelerator line extraction system |
| JP2022137327A (en) * | 2021-03-09 | 2022-09-22 | 博文 福山 | Ion beam analysis measurement chamber |
| CN115843146A (en) * | 2022-12-02 | 2023-03-24 | 杭州嘉辐科技有限公司 | Thin-wall vacuum tube and vacuum chamber |
| CN116175091A (en) * | 2022-12-30 | 2023-05-30 | 兰州科近泰基新技术有限责任公司 | A dodecagonal vacuum chamber manufacturing process for heavy ion cancer treatment device |
| CN117042280A (en) * | 2023-09-19 | 2023-11-10 | 兰州科近泰基新技术有限责任公司 | Thin-wall vacuum chamber and manufacturing method thereof |
-
2024
- 2024-07-30 CN CN202411032076.2A patent/CN118843248B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115921899A (en) * | 2023-03-09 | 2023-04-07 | 中国科学院近代物理研究所 | A method of manufacturing a titanium alloy thin-walled ribbed extremely high vacuum chamber |
Also Published As
| Publication number | Publication date |
|---|---|
| CN118843248A (en) | 2024-10-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1048594A (en) | Electromagnetic Flowmeter | |
| CN118843248B (en) | A heavy ion scanning beam transport vacuum chamber based on composite flange profiled wall | |
| CN110657327B (en) | Spliced ring gear track and its horizontality and coaxiality pose decoupling adjustment method | |
| JP2011237294A (en) | Leakage inspection apparatus and connecting hose for leakage inspection | |
| JP5709776B2 (en) | Welded pipe shape measuring device | |
| CN108831812B (en) | vacuum tubes for accelerators | |
| CN219244909U (en) | Rectangular workpiece helium leakage detection jig | |
| CN217032943U (en) | Air tightness detection device | |
| CN104614559B (en) | Object under test mobile device in a kind of vacuum system of dual U-shaped | |
| CN116788463A (en) | A precise installation method for ship segmented pipe assemblies | |
| CN212303103U (en) | A neutron shielding pipeline for high vacuum environment | |
| KR101642077B1 (en) | Vaccum chamber and manufacturing method thereof | |
| CN210687714U (en) | A Total Station Fixing Device for Shield Tunnel Construction | |
| CN111726929A (en) | An adapter assembly for accelerating the outlet of the tube | |
| JP2022137327A (en) | Ion beam analysis measurement chamber | |
| WO2022227705A1 (en) | Air conditioner temperature-sensing probe mounting structure and air conditioner | |
| CN211779501U (en) | Detachable spliced corrugated pipe | |
| CN222874312U (en) | Mechanical flange centering corrector | |
| CN110719682A (en) | A combined vacuum differential structure | |
| Hsiung et al. | TPS Vacuum system | |
| CN210221427U (en) | Sealing performance inspection mechanism for semiconductor equipment | |
| CN219712682U (en) | Expansion joint and mechanical connection equipment | |
| CN212986346U (en) | Connecting pipe, pipeline connector and pipeline assembly | |
| CN222913578U (en) | A comparison test block for pipes in ultrasonic automatic testing system | |
| CN110739195A (en) | A device, system and method for adjusting the coaxiality of cathode and focusing electrode of electron gun |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |