CN119113579A - A plasma separation device - Google Patents
A plasma separation device Download PDFInfo
- Publication number
- CN119113579A CN119113579A CN202411277724.0A CN202411277724A CN119113579A CN 119113579 A CN119113579 A CN 119113579A CN 202411277724 A CN202411277724 A CN 202411277724A CN 119113579 A CN119113579 A CN 119113579A
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- China
- Prior art keywords
- main cylinder
- bottom end
- liquid outlet
- support
- separation device
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/08—Thickening liquid suspensions by filtration
- B01D17/085—Thickening liquid suspensions by filtration with membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/12—Auxiliary equipment particularly adapted for use with liquid-separating apparatus, e.g. control circuits
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Thermal Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention discloses a plasma separation device, which comprises a first main cylinder, a second main cylinder and a separation assembly, wherein the bottom end of the separation assembly comprises the first main cylinder and is detachably connected to a filter bucket through a plurality of locking plates, the filter bucket comprises a plurality of support plates, each support plate is connected through a cell filter membrane, a support ring is arranged on the inner bottom wall of the second main cylinder, the top end of the support ring is simultaneously contacted with the bottom ends of all support plates, a communication groove is formed in the bottom end of the upper side of the support plate, a liquid outlet is formed in the outer side of the second main cylinder, and the lowest point of the liquid outlet is not higher than the lowest point of the communication groove.
Description
Technical Field
The invention relates to the technical field of plasma separation, in particular to a plasma separation device.
Background
Plasma is an important component of blood, and its main function in blood is to carry blood cells, transport substances required for maintaining vital activities of human body and waste produced in vivo, etc., blood examination is generally involved in medical examination, and conventional separation means is to centrifuge a sampling tube after standing, and suck supernatant in the sample to separate plasma.
However, most of the existing separation devices use the supernatant through the dropper to separate the plasma after the blood sample is kept still and centrifuged, which usually takes a long time and requires repeated sucking actions by the inspector, resulting in low separation efficiency and easy delay of the judgment of the patient's condition.
Disclosure of Invention
The invention provides a plasma separation device, which solves the problems that in the prior art, most of blood samples are kept stand and centrifuged, and then supernatant is taken through a dropper to separate plasma, the process is generally long in time consumption, and repeated sucking actions are required by a inspector, so that the separation efficiency is low, and the judgment of the illness state of a patient is easy to delay.
In order to achieve the above purpose, the present invention provides the following technical solutions:
The utility model provides a plasma separator, includes first main section of thick bamboo, second main section of thick bamboo and separation subassembly, separation subassembly includes first main section of thick bamboo bottom is connected to the filter pulp through polylith locking plate detachably, the filter pulp includes polylith extension board, every all connect through cell filter membrane between the extension board, be provided with the supporting ring on the diapire in the second main section of thick bamboo, the supporting ring top simultaneously with all the extension board bottom is contacted, the intercommunication groove has been seted up to extension board upside bottom, the liquid outlet has been seted up in the second main section of thick bamboo outside, the liquid outlet nadir is not higher than the intercommunication groove nadir.
Preferably, the top of the inner side wall of the first main cylinder is connected with a guide hopper, the bottom end of the guide hopper is connected with a connecting pipe, the bottom end of the connecting pipe is simultaneously clamped with all the locking plates, the bottom end of the outer wall of the first main cylinder is provided with a connecting cover, and the connecting cover is in threaded connection with the second main cylinder.
Preferably, the bottom end of the second main cylinder is provided with a supporting component, the supporting component comprises two groups of connecting blocks connected to the outer bottom wall of the second main cylinder, each group of connecting blocks is hinged with a pair of support legs, two support legs are arranged in a staggered mode, a sliding groove is formed in each support leg, the outer side of the second main cylinder is connected with a control rod through a telescopic rod, and the control rods penetrate through the two pairs of sliding grooves formed in the support legs.
Preferably, the outer end of the liquid outlet is hinged with a drainage rod, the outer end of the liquid outlet is provided with a clamping groove, the drainage rod is clamped in the clamping groove, the outer end of the liquid outlet is provided with a baffle in a sliding clamping manner, and the baffle is blocked outside the clamping groove.
Preferably, the overflow launder is provided with in the second main section of thick bamboo outside, overflow launder top opening height is higher than the highest height of filter pulp, the holding ring orientation the overflow launder direction has been seted up and has been let out the mouth, let out the mouth with the overflow launder intercommunication, overflow launder top slip card is equipped with the gag lever post, the gag lever post bottom is provided with the floater, second main section of thick bamboo outer wall connection has pressure sensor, the gag lever post in vertical direction with pressure sensor sensing end aligns.
Preferably, the first main section of thick bamboo bottom is provided with first sealing ring, first sealing ring card is established the second main section of thick bamboo top, the connecting pipe bottom is provided with the second sealing ring, the second sealing ring joint is in the filter pulp top.
The principle and beneficial effect of this technical scheme:
(1) The separation component provided by the invention can automatically separate plasma in blood, and the cell filter membrane obliquely arranged on the filter funnel can balance the bearing force of the cell filter membrane, so that the blood flows to the high side of the cell filter membrane through the cell filter membrane, the self weight of the filter membrane and the liquid pressure can be overlapped to filter the plasma, the service life of the filter membrane is prolonged, and the filtering efficiency is improved.
(2) The supporting component arranged in the invention can lift the whole device, so that a tester can use different containers to contain plasma, when the device needs to be lifted, the telescopic rod is driven to extend, the control rod connected with one end of the telescopic rod moves downwards and drives the two pairs of support legs to rotate along the connecting block through the sliding groove until the two pairs of support legs lift the device to the designated height.
(3) The pressure sensor provided by the invention can help test staff monitor the accumulation amount of blood cells in the second main cylinder in real time, when the liquid level accumulated in the second main cylinder reaches a certain height, the liquid buoyancy in the overflow groove can drive the floating ball and the limit rod arranged at the top end of the floating ball to move upwards, the limit rod can collide with and press the sensing end of the pressure sensor, and at the moment, the pressure sensor can prompt the test staff to stop adding blood samples and lead out part of blood cells through the top end opening of the overflow groove.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present invention;
FIG. 2 is a schematic diagram of the split structure of the present invention;
FIG. 3 is an enlarged schematic view of the area A in FIG. 2;
FIG. 4 is a schematic view of the present invention in cross-section;
FIG. 5 is an enlarged schematic view of the area B in FIG. 4;
the reference numerals in the attached drawings of the specification comprise 1, a first main cylinder, 2, a second main cylinder, 3, a communicating groove, 4, a clamping groove, 5, a drainage rod, 6, a telescopic rod, 7, a baffle, 8, a liquid outlet, 9, a connecting block, 10, support legs, 11, a chute, 12, a control rod, 13, a guide hopper, 14, a connecting cover, 15, a connecting pipe, 16, a pressure sensor, 17, a limiting rod, 18, a floating ball, 19, an overflow groove, 20, a drainage port, 21, a first sealing ring, 22, a cell filter membrane, 23, a locking plate, 24, a second sealing ring, 25, a filter hopper, 26, a support plate, 27 and a support ring.
Detailed Description
The invention is described in further detail below with reference to the attached drawings and embodiments:
Examples:
As shown in fig. 1 to 5, the invention provides a plasma separating device, which comprises a first main cylinder 1, a second main cylinder 2 and a separating component, wherein the bottom end of the first main cylinder 1 is detachably connected to a filter bucket 25 through a plurality of locking plates 23, the filter bucket 25 comprises a plurality of support plates 26, each support plate 26 is connected through a cell filter membrane 22, a support ring 27 is arranged on the inner bottom wall of the second main cylinder 2, the top ends of the support rings 27 are simultaneously contacted with the bottom ends of all support plates 26, a communication groove 3 is formed in the bottom end of the upper side of the support plates 26, a liquid outlet 8 is formed in the outer side of the second main cylinder 2, and the lowest point of the liquid outlet 8 is not higher than the lowest point of the communication groove 3.
As shown in fig. 1, 4 and 5, the top end of the inner side wall of the first main cylinder 1 is connected with a guide hopper 13, the bottom end of the guide hopper 13 is connected with a connecting pipe 15, the bottom end of the connecting pipe 15 is simultaneously clamped with all the locking plates 23, the bottom end of the outer wall of the first main cylinder 1 is provided with a connecting cover 14, and the connecting cover 14 is in threaded connection with the second main cylinder 2.
As shown in fig. 1 to 3, the bottom end of the second main cylinder 2 is provided with a supporting component, the supporting component comprises two groups of connecting blocks 9 connected to the outer bottom wall of the second main cylinder 2, each group of connecting blocks 9 is hinged with a pair of support legs 10, the two support legs 10 are arranged in a staggered manner, a sliding groove 11 is formed in each support leg 10, the outer side of the second main cylinder 2 is connected with a control rod 12 through a telescopic rod 6, and the control rod 12 is simultaneously arranged in the sliding groove 11 formed in each pair of support legs 10 in a penetrating manner.
The supporting component can raise the whole device so that a tester can use different containers to contain plasma, when the device needs to be raised, the telescopic rod 6 is driven to stretch, the control rod 12 connected with one end of the telescopic rod 6 moves downwards and drives the two pairs of support legs 10 to rotate along the connecting block 9 through the sliding groove 11 until the two pairs of support legs 10 raise the device to a designated height.
As shown in fig. 3, the outer end of the liquid outlet 8 is hinged with a drainage rod 5, the outer end of the liquid outlet 8 is provided with a clamping groove 4, the drainage rod 5 is clamped in the clamping groove 4, the outer end of the liquid outlet 8 is slidably clamped with a baffle 7, and the baffle 7 is blocked outside the clamping groove 4.
As shown in fig. 1 and fig. 3 to fig. 5, an overflow groove 19 is arranged on the outer side of the second main cylinder 2, the top end opening of the overflow groove 19 is higher than the highest height of the filter bucket 26, a drainage port 20 is formed in the direction of the support ring 7 towards the overflow groove 19, the drainage port 20 is communicated with the overflow groove 19, a limit rod 17 is clamped on the top end of the overflow groove 19 in a sliding manner, a floating ball 18 is arranged at the bottom end of the limit rod 17, a pressure sensor 16 is connected to the outer wall of the second main cylinder 2, and the limit rod 17 is aligned with the sensing end of the pressure sensor 16 in the vertical direction.
The pressure sensor 16 can help test personnel monitor the accumulation amount of blood cells in the second main cylinder 2 in real time, because the second main cylinder 2 is communicated with the overflow groove 19 through the drainage port 20, the liquid level in the second main cylinder 2 and the overflow groove 19 should be equal, when the accumulated liquid level in the second main cylinder 2 reaches a certain height, the liquid buoyancy in the overflow groove 19 can drive the floating ball 18 and the limiting rod 17 arranged at the top end of the floating ball to move upwards, the limiting rod 17 can collide and press the sensing end of the pressure sensor 16, and at the moment, the pressure sensor 16 can prompt the test personnel to stop adding blood samples and lead out partial blood cells through the top end opening of the overflow groove 19.
As shown in fig. 1 and 5, the bottom end of the first main cylinder 1 is provided with a first sealing ring 21, the first sealing ring 21 is clamped at the top end of the second main cylinder 2, the bottom end of the connecting pipe 15 is provided with a second sealing ring 24, and the second sealing ring 24 is clamped at the top end of the filter bucket 25.
Specific use and action of the embodiment:
When the device is used for separating plasma, a blood sample is injected into the first main cylinder 1 through the guide hopper 13 connected with the top end of the first main cylinder 1, the blood sample enters the filter hopper 25 along the connecting pipe 15, the blood sample is accumulated in the second main cylinder 2 connected with the bottom end of the first main cylinder 1, when the liquid level of the blood sample contacts the cell filter membrane 22, the plasma finally flows to the liquid outlet 8 arranged on the outer side of the second main cylinder 2 through the cell filter membrane 22 under extrusion, meanwhile, as the plasma is lighter in blood components, the plasma accumulated on the lower side finally moves upwards and enters the space between the second main cylinder 2 and the cell filter membrane 22 through the cell filter membrane 22, the obliquely arranged cell filter membrane 22 can balance the bearing capacity of the cell filter membrane 22, so that the blood flows to the high side of the cell filter membrane 22 through the cell filter membrane 22, the self-weight of the filter membrane is overlapped with the liquid pressure to filter the plasma, the filtering efficiency is improved, the service life of the filter membrane is prolonged, and the plasma finally flows to the liquid outlet 8 arranged on the outer side of the second main cylinder 2, and then flows to an external storage container through the liquid outlet 8, and the plasma is discharged to the outer side of the cell filter membrane 22, and the plasma is smoothly discharged to the outer side 7, namely the plasma can be smoothly discharged to the drain channel 5 through the guide channel 5, and the plasma can be arranged at the proper drainage angle;
When the filter bucket 25 needs to be cleaned or replaced periodically, the first main cylinder 1 is directly rotated to be separated from the second main cylinder 2, the filter bucket 25 is rotated along the horizontal direction, the locking plate 23 at the top end of the filter bucket 25 is separated from the locking groove where the filter bucket 25 is currently located, the filter bucket 25 is disassembled downwards at the moment, a new filter bucket 25 is clamped into the bottom end of the connecting pipe 15 according to the position of the original filter bucket 25, and the sealing performance of the detachable components after reconnection can be ensured by arranging the first sealing ring 21 and the second sealing ring 24.
The foregoing is merely exemplary of the present application, and specific technical solutions and/or features that are well known in the art have not been described in detail herein. It should be noted that, for those skilled in the art, several variations and modifications can be made without departing from the technical solution of the present application, and these should also be regarded as the protection scope of the present application, which does not affect the effect of the implementation of the present application and the practical applicability of the patent. The protection scope of the present application is subject to the content of the claims, and the description of the specific embodiments and the like in the specification can be used for explaining the content of the claims.
Claims (6)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411277724.0A CN119113579A (en) | 2024-09-12 | 2024-09-12 | A plasma separation device |
| BE20245764A BE1031775B1 (en) | 2024-09-12 | 2024-11-06 | PLASMA SEPARATOR |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202411277724.0A CN119113579A (en) | 2024-09-12 | 2024-09-12 | A plasma separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN119113579A true CN119113579A (en) | 2024-12-13 |
Family
ID=93562883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202411277724.0A Withdrawn CN119113579A (en) | 2024-09-12 | 2024-09-12 | A plasma separation device |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN119113579A (en) |
| BE (1) | BE1031775B1 (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7790117B2 (en) * | 2008-03-21 | 2010-09-07 | Scientific Plastic Products, Inc. | Filter vial |
| WO2012166291A2 (en) * | 2011-05-04 | 2012-12-06 | Restek Corporation | Protective barrier against contamination from sample preparation and extraction devices |
| CN116943429A (en) * | 2023-09-08 | 2023-10-27 | 德莫德（苏州）机械科技有限公司 | Plasma quick separator |
-
2024
- 2024-09-12 CN CN202411277724.0A patent/CN119113579A/en not_active Withdrawn
- 2024-11-06 BE BE20245764A patent/BE1031775B1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| BE1031775B1 (en) | 2025-09-18 |
| BE1031775A1 (en) | 2025-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20241213 |