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CN119819497B - Automatic realize vertical centrifuge of centrifugal cup - Google Patents

Automatic realize vertical centrifuge of centrifugal cup

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Publication number
CN119819497B
CN119819497B CN202510173246.7A CN202510173246A CN119819497B CN 119819497 B CN119819497 B CN 119819497B CN 202510173246 A CN202510173246 A CN 202510173246A CN 119819497 B CN119819497 B CN 119819497B
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China
Prior art keywords
centrifugal
magnetic
cup
centrifuge
magnetic attraction
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CN202510173246.7A
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CN119819497A (en
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马咏翔
李佳
高宁
张大伟
张阳阳
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Beijing Errui Xinyue Technology Co ltd
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Beijing Errui Xinyue Technology Co ltd
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Publication of CN119819497A publication Critical patent/CN119819497A/en
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Abstract

The invention discloses an automatic centrifugal machine for realizing the verticality of centrifugal cups, which comprises a plurality of centrifugal cups, a magnetic structure, a magnetic attraction structure and a magnet induction structure, wherein the centrifugal cups are arranged on a centrifugal turntable, the magnetic structure is of a sheet type structure and is fixed at the bottom of each centrifugal cup, the magnetic attraction structure is arranged in the centrifugal machine, the magnetic attraction structure is attracted by the magnetic attraction quantity of the magnetic attraction structure and is driven to rotate, the centrifugal cups are finally driven to rotate, the movement stop state of the centrifugal cups is the verticality of the centrifugal cups, the centrifugal turntable rotates to drive the centrifugal cups to pass through the magnetic attraction structure and generate the magnetic attraction action, each centrifugal cup is enabled to reach the verticality after rotating for 360 degrees, the magnet induction structure which can only induce the magnetic structure on the centrifugal cups in the vertical state is additionally arranged, whether the centrifugal cups are in the vertical state or not is monitored, and after the centrifugal cups are in the vertical state through the cooperation of the magnetic structure, the magnetic attraction structure and the magnet induction structure, the centrifugal cups are enabled to enter the next automatic exosome enrichment stage.

Description

Automatic realize vertical centrifuge of centrifugal cup
Technical Field
The invention belongs to the field of centrifuges, and particularly relates to the technical field of centrifuges for automatically placing various centrifuge tubes in a vertical state into the centrifuges for centrifugal treatment or taking out the centrifuge tubes from the centrifuges, in particular to an automatic centrifuge for realizing the vertical centrifugal cup.
Background
The blood-derived neurogenic exosome enrichment is a complex process, consumes more manpower, is easy to cause operation errors due to improper operation, and therefore needs an automatic exosome enrichment device, 202110247374.3 an automatic device for effectively enriching neurogenic exosomes in blood and 202210874984.0 an exosome enrichment system, 202410109881.4 a blood-derived neurogenic exosome enrichment device and other prior arts disclose an automatic enrichment device, namely a gradual iterative process, which not only faces the problem of integrity but also faces the problem of specific structures when being implemented specifically.
Because the exosome automation apparatus rotates an operation state of uncapping, and the centrifuge tube is placed in the centrifuge in a vertical state or taken out from the centrifuge in the process, so as to ensure the feasibility of the automation operation process, how to keep the centrifuge tube in the centrifuge in a vertical state all the time is a technical problem to be solved, 202410730340.3 a centrifuge, which discloses a safe and effective centrifugal inclination angle when a rotor (a centrifugal cup) is limited in a limiting groove, and a centrifugal cup can be kept under the condition that the center of the rotor is lower than a rotating shaft through a heavier part arranged at the bottom of the rotor, so that the vertical state of the rotating shaft is kept under the condition of stopping, but the vertical state can be kept after the centrifugation through the mode of increasing the weight of the bottom of the rotor, but the centrifugal force is greatly increased due to the weight of the rotor, so that the centrifugal work load is increased, and the centrifugal force is not met by a small-sized motor, and finally the whole product is also enlarged, so that the technical scheme of keeping the vertical state of the centrifugal cup can be ensured on the premise that the centrifugal cup is kept under the premise that the centrifugal force is kept by the small centrifugal motor.
The invention provides an automatic centrifugal machine for realizing the vertical direction of a centrifugal cup.
Disclosure of Invention
Aiming at the problem that the centrifugal machine in the prior art 202410730340.3 is poor in enrichment effect due to the fact that the centrifugal cup weight is increased to cause effective centrifugal force which cannot be achieved when a small centrifugal machine motor is used for enriching exosomes from blood sources, if the centrifugal machine with a larger motor is replaced, the occupied space of the whole exosome instrument is greatly increased, and the technical route of miniaturizing the exosome enrichment instrument is not consistent with that of the prior art, a new technical scheme for maintaining the centrifugal cup in a vertical state in the centrifuge tube taking and placing process on the premise that the centrifugal cup weight is not increased or is little increased is needed to be found urgently.
The invention adopts a lighter centrifugal cup, and the centrifugal cup has the technical characteristics of maintaining the vertical state, and other modes are basically the same as those of a 202410730340.3 centrifugal machine. Specifically, a thin-sheet magnetic structure is arranged at the bottom of each centrifugal cup, the plane of the bottom of the thin-sheet magnetic structure is perpendicular to the longitudinal axis of the centrifugal cup, a magnetic attraction structure is arranged at the bottom of the centrifugal machine, when a single centrifugal cup rotates to the position of the magnetic attraction structure, the attraction force of the magnetic attraction structure controls the thin-sheet structure to move close to the magnetic attraction structure, the magnetic attraction structure is arranged under the thin-sheet magnetic structure under the final stop state, the thin-sheet magnetic structure drives the centrifugal cup to maintain the vertical state, the thin-sheet magnetic structure can be ensured to attract the thin-sheet magnetic structure to the vertical state due to the arrangement, but because the magnetic structure is a thin-sheet structure, the weight image of the centrifugal cup is not large, and therefore, the smaller centrifugal machine can meet the requirement on centrifugal force when exosome is enriched.
In particular to an automatic centrifugal machine for realizing the vertical of a centrifugal cup, which comprises
The centrifugal cups can rotate from a vertical state to a direction far away from the center of the centrifugal machine, a plurality of centrifugal cups are arranged on the centrifugal turntable, and centrifugal tubes are arranged in the centrifugal cups;
The magnetic structure is a sheet structure, and a magnetic structure is fixedly arranged at the bottom of each centrifugal cup;
the magnetic attraction structure is arranged in the centrifugal machine, the magnetic attraction quantity of the magnetic attraction structure attracts the magnetic structure to perform magnetic attraction action close to the magnetic attraction structure, meanwhile, the centrifugal cup fixedly connected with the magnetic structure is driven to rotate, and finally, the motion stop state of the centrifugal cup is the vertical state of the centrifugal cup, and the magnetic attraction structure is not arranged on the centrifugal turntable;
The centrifugal turntable rotates to drive different centrifugal cups to pass through the magnetic attraction structure, the magnetic attraction structure attracts the magnetic structure at the bottom of each centrifugal cup to generate magnetic attraction action, so that each centrifugal cup passing through the magnetic attraction structure completes the magnetic attraction action to reach a vertical state, and each centrifugal cup is maintained in the vertical state after the centrifugal turntable rotates for 360 degrees.
Further, in the vertical adjustment state of the centrifugal cups, the centrifugal turntable is controlled to maintain a rotation speed of less than 60 degrees per second, or when each centrifugal cup rotates to a position above the corresponding position of the magnetic attraction structure, the centrifugal cup is stopped for 0.5-1 s, so that sufficient time is ensured to drag the centrifugal cup.
Furthermore, a verification structure for judging whether the centrifugal cup is in a vertical state is further arranged to avoid the influence of a non-vertical state caused by incomplete magnetic attraction action on subsequent operation, specifically, a magnet induction structure is arranged in the centrifugal machine and can only induce a magnetic structure in the vertical state of the centrifugal cup, when the centrifugal cup rotates to a magnetic induction structure induction area, and when the centrifugal cup is in the vertical state, the magnet induction structure induces the magnetic structure, otherwise, the magnetic structure cannot be induced, and the centrifugal cup is proved not to be in the vertical state. Whether the centrifugal cup is in a vertical state after the magnetic attraction action of the magnetic structure can be effectively monitored through the magnet induction structure, and the phenomenon that equipment operation is affected due to the fact that the non-vertical state caused by insufficient magnetic attraction action or the fault of the centrifugal cup enters the next flow stage is avoided.
Further, when the centrifugal cups rotate to the magnetic induction structure induction area, but the centrifugal cups are not in the vertical state, the magnetic induction structure cannot induce the magnetic structure, the centrifugal turntable is controlled to rotate to the position where the magnetic induction structure is located to conduct magnetic attraction action again, so that the centrifugal cups are in the vertical state and then rotate to the position of the magnetic induction structure again, or the centrifugal cups are marked, the mark of the centrifugal cups which do not induce the magnetic structure is recorded, after the centrifugal cups are rotated for 360 degrees to complete induction, the magnetic attraction action is conducted again according to the recorded mark of the centrifugal cups which do not induce the magnetic structure, the centrifugal cups are in the vertical state again, and then verification of whether the centrifugal cups are in the vertical state is conducted through the magnetic induction structure.
Further, when the magnetic structure at the bottom of the centrifugal cup cannot be sensed for the second time, an alarm signal is sent out, the operation is stopped, the corresponding centrifugal cup which cannot be sensed for the magnetic structure is checked, and the centrifugal cup is guaranteed to be of a normal structure.
Further, be provided with the centrifuge lid on the centrifuge, set up the operation mouth that operation apparatus entered into in the centrifuge on the lid, the magnetism is inhaled the structure and is set up the centrifuge position at operation mouth place, and the purpose of this kind of setting is in order to inhale the magnetism of structure and inhale the action of putting of centrifuging tube down for the centrifugal cup maintains a more stable vertical state, guarantees to get the stability of putting the operation.
Further, the centrifugal turntable is rotated in a clockwise or anticlockwise direction, and the magnet sensing structure is arranged at a position behind the rotation direction of the magnetic attraction structure, and the interval angle of the magnet sensing structure and the magnet sensing structure is a multiple of the interval angle of every two centrifugal cups.
Further, the magnet sensing structures are disposed 180 apart, the purpose of which is to space the structures apart to facilitate the placement of the structures without mutual infection.
Further, the magnetic structure is a magnetic sheet attached to the bottom of the centrifugal cup, the magnetic attraction structure is an electromagnetic chuck, when the magnetic structure enters the upper part of the electromagnetic chuck, the magnetic attraction action is carried out by electrifying, the power is cut off after the magnetic attraction action is finished, and the risk that the centrifugal cup in a vertical state is attracted again due to unnecessary magnetic attraction operation when the magnetic attraction action is not needed can be avoided by the way of cutting off the power at intervals.
Further, the bottom of the inner side of the centrifugal cup is set to be a plane, and the magnetic sheet is attached to the plane of the bottom of the inner side of the centrifugal cup, so that the risk caused by the separation of the magnetic sheet from the centrifugal cup due to long-term centrifugal force during centrifugation can be effectively avoided.
Further, the magnet induction structure is a Hall sensor, and the structure is a common magnetic structure for monitoring, but the adjustment of the vertical state of the centrifugal cup and the monitoring of whether the centrifugal cup is in the vertical state are accomplished through the cooperation of the Hall sensor, the patch and the electromagnetic chuck, so that the centrifugal cup has obvious new innovation.
The invention has the beneficial effects that
Through setting up the cooperation of the magnetism structure of inhaling in structure and every centrifugal cup on non-centrifugal carousel, take place the magnetism and inhale the action for every centrifugal cup can reach vertical state, and whole process only need just can realize through 360 rotations of centrifugal carousel, because magnetism inhale the structure and not set up on centrifugal carousel, so the centrifugal carousel bulk weight increase of taking place centrifugal action is few, can just can satisfy the required centrifugal force of exosome enrichment through very little centrifugal motor, satisfies the miniaturized demand of whole exosome enrichment apparatus.
Through setting up the magnet induction structure of verifying whether the centrifugal cup is in vertical state to inhale the structure cooperation with magnetism and can further guarantee that the centrifugal cup is in vertical state, avoid because the magnetism of structure is inhaled the action and is not put in place or the follow-up operation risk of the non-vertical state that the problem of centrifugal cup itself led to.
The centrifugal cup can be further ensured to be in a vertical state by respectively executing the rotation of the two wheels at the magnetic attraction structure position and the magnet induction structure position by 360 degrees through the centrifugal turntable, and the whole program setting is simple through the rotation mode of the two wheels by 360 degrees.
The device can ensure timely overhaul of equipment by continuously sensing the setting that the magnetic structure can not be sensed for 2 times, so that the enrichment instrument overall mode caused by the fact that problems cannot be found in time is prevented from being at more fault risks, and the accuracy of the enrichment quantity of the exosome is also ensured.
Through the bottom setting mode with magnetic structure setting in centrifugal cup inboard, can avoid the apparatus trouble risk that magnetic structure and centrifugal cup separation caused under the effect of strong centrifugal force.
Drawings
FIG. 1 is a schematic view of the overall longitudinal cross-sectional structure of a centrifuge according to the present invention;
FIG. 2 is a schematic view of a partial enlarged structure of a portion A of the centrifuge of the present invention as a whole;
FIG. 3 is a schematic view of a part B partially enlarged structure of the centrifuge of the present invention;
FIG. 4 is a schematic diagram of the overall structure of the capless centrifuge of the present invention;
FIG. 5 is a schematic diagram of the overall structure of the capped centrifuge of the present invention;
Description of the main reference numerals
1. The centrifugal rotary table comprises a centrifugal rotary table body, a centrifugal cup, a magnetic structure, a magnetic attraction structure, a magnet induction structure, a centrifugal rotary table body, a centrifugal rotary table cover body, an operation port, a centrifugal machine outer cabin, a centrifugal motor and a centrifugal tube.
Detailed Description
An automatic centrifugal machine for realizing the verticality of centrifugal cups 12 comprises centrifugal cups 12, a magnetic structure 2, a centrifugal plate and a centrifugal plate, wherein the centrifugal cups 12 can rotate from a vertical state to a direction far away from the center of the centrifugal machine, a plurality of centrifugal cups 12 are arranged on a centrifugal turntable 1, centrifugal tubes 7 are arranged in the centrifugal cups 12, and the magnetic structure 2 is fixed at the bottom of each centrifugal cup 12;
The centrifugal cup also comprises a magnetic attraction structure 3, one magnetic attraction structure is arranged in the centrifugal machine, the magnetic attraction amount of the magnetic attraction structure 3 attracts the magnetic structure 2 to perform magnetic attraction action close to the magnetic attraction structure 3, meanwhile, the centrifugal cup 12 fixedly connected with the magnetic structure 2 is driven to rotate, and finally, the motion stop state of the centrifugal cup 12 is the vertical state of the centrifugal cup 12, and the magnetic attraction structure 3 is not arranged on the centrifugal turntable 1; the centrifugal turntable 1 rotates to drive different centrifugal cups 12 to pass through the magnetic attraction structure 3, the magnetic attraction structure 3 attracts the magnetic structure 2 at the bottom of each centrifugal cup 12 to generate magnetic attraction action, so that each centrifugal cup 12 passing through the magnetic attraction structure 3 completes the magnetic attraction action to reach a vertical state, and each centrifugal cup 12 is maintained in the vertical state after the centrifugal turntable 1 rotates for 360 degrees.
In a more preferred embodiment, the centrifugal turntable 1 is controlled to maintain a rotational speed of less than 60 ° per second in the vertical adjustment state of the centrifugal cups 12, or to stop for 0.5-1s when each centrifugal cup 12 rotates above the corresponding position of the magnetic attraction structure 3, to ensure sufficient time to drag the centrifugal cups 12.
In a more preferred embodiment, a magnet induction structure 4 is arranged in the centrifugal machine, and can only induce the magnetic structure 2 in the vertical state of the centrifugal cup 12, when the centrifugal cup 12 rotates to the induction area of the magnet induction structure 4 and the centrifugal cup 12 is in the vertical state, the magnet induction structure 4 induces the magnetic structure 2, the centrifugal turntable 1 rotates to enable the next centrifugal cup 12 to enter the induction area of the magnet induction structure 4 for verifying whether the centrifugal cup 12 is in the vertical state, and the next operation stage is entered after verification until all the centrifugal cups 12 are verified to be in the vertical state.
In a more preferred embodiment, when the centrifugal cups 12 rotate to the sensing area of the magnet sensing structure 4, but the centrifugal cups 12 are not in the vertical state, the magnet sensing structure 4 cannot sense the magnetic structure 2, then the centrifugal turntable 1 is controlled to rotate to the position of the magnet sensing structure 3 to perform the magnetic attraction again, so that the centrifugal cups 12 are in the vertical state, and then the centrifugal cups are rotated to the position of the magnet sensing structure 4 again, or the centrifugal cups 12 are marked, the marks of the centrifugal cups 12 which do not sense the magnetic structure 2 are recorded, after the centrifugal cups 12 are rotated for 360 degrees to complete sensing, the magnetic attraction is performed again according to the recorded marks of the centrifugal cups 12 which are not sensed, the centrifugal cups 12 are again in the vertical state, and then the magnetic sensing structure 4 is used for verifying whether the centrifugal cups are in the vertical state.
In a more preferred embodiment, when the magnetic structure 2 at the bottom of the centrifugal cup 12 cannot be sensed for the second time, an alarm signal is sent out, the operation is stopped, the corresponding centrifugal cup 12 which cannot be sensed for the magnetic structure 2 is checked, and the centrifugal cup 12 is ensured to be in a normal structure.
In a more preferred embodiment, all centrifugal cups 12 are marked, the centrifugal cups 12 marked as one are controlled to be positioned above the magnetic attraction structure 3, the centrifugal cups 12 on the centrifugal turntable 1 are sequentially rotated by 360 degrees according to the program direction, so that the centrifugal cups 12 are positioned in a vertical state, meanwhile, when the first centrifugal machine enters an induction area of the magnet induction structure 4 after finishing the magnetic attraction operation, the induction operation is triggered and the centrifugal cups are rotated by 360 degrees according to the program, the mark of the centrifugal cups 12 which are not sensed in the vertical state is recorded in the process, after the verification of first run degrees is finished, the recorded centrifugal cups 12 which are not sensed in the vertical state are sequentially rotated above the magnetic attraction structure 3 again, the magnetic attraction operation is performed again, the centrifugal cups 12 are rotated to the induction area of the magnet induction structure 4 again after the magnetic attraction operation, the 360-degree rotation of the second wheel which is driven by the magnet induction structure 4 is finished again, and finally the centrifugal cups 12 marked as one are positioned above the magnetic attraction structure 3 is controlled, and the magnetic attraction structure 3 is started. All centrifugal cups 12 are in the vertical state after the two rounds of magnetic attraction and the verification of whether the centrifugal cups are in the vertical state or not, and the centrifugal cups 12 marked as one are used as the starting point, so that the centrifugal tube 7 at the next stage is taken out or put in. The service is stopped if there is no centrifugal cup 12 in the vertical position sensed yet through 360 ° rotation of the two wheels. Through 360-degree rotation of the two wheels, the recording and the operation can be very convenient, and the whole program can be very smooth.
More preferred embodiment is, be provided with centrifuge lid 5 on the centrifuge, set up the operation mouth 51 that the operation apparatus of operation entered into in the centrifuge on the lid, the magnetism is inhaled structure 3 and is set up the centrifuge position that is located at operation mouth 51, and the purpose of this kind of setting is in order to inhale the action of getting of centrifuging tube 7 under the magnetism of structure 3 and inhale for centrifugal cup 12 maintains a more stable vertical state, guarantees the stability of getting and putting the operation.
In a more preferred embodiment, the centrifugal turntable 1 is rotated in a clockwise or counterclockwise direction, and the magnet sensing structure 4 is disposed at a position behind the rotation direction of the magnet attraction structure 3, and the interval angle of the magnet sensing structure and the magnet attraction structure is a multiple of the interval angle of every two centrifugal cups 12.
In a more preferred embodiment, the magnet sensing structures 4 are arranged 180 ° apart, the purpose of which is to space the structures apart so as to facilitate the arrangement of the individual structures without infection of each other.
In a more preferred embodiment, the magnetic structure 2 is a magnetic sheet attached to the bottom of the centrifugal cup 12, the magnetic attraction structure 3 is an electromagnetic chuck, when the magnetic structure 2 enters the upper part of the electromagnetic chuck, the magnetic attraction action is performed by electrifying, and the power is cut off after the magnetic attraction action is finished, so that the risk that the centrifugal cup 12 in a vertical state is attracted again due to unnecessary magnetic attraction operation when the magnetic attraction action is not needed can be avoided by adopting the mode of cutting off the power at intervals.
In a more preferred embodiment, the bottom of the inner side of the centrifugal cup 12 is provided with a plane, and the magnetic sheet is attached to the plane of the bottom of the inner side of the centrifugal cup 12, so that the risk caused by the separation of the magnetic sheet from the centrifugal cup 12 due to long-term centrifugal force during centrifugation can be effectively avoided.
In a more preferred embodiment, the magnet sensing structure 4 is a hall sensor, and this is a common structure for monitoring the magnetic structure 2, but the adjustment of the vertical state of the centrifugal cup 12 and the monitoring of whether the centrifugal cup is in the vertical state are accomplished by the cooperation of the hall sensor, the patch and the electromagnetic chuck, which is obviously innovative.
In a more preferred embodiment, the centrifugal turntable 1 has a closed bottom, and the bottom is of a thin bottom structure, so that the thin bottom structure does not interfere the magnetic attraction force and induction force of the electromagnetic chuck and the hall sensor on the magnetic sheet. The arrangement of the closed centrifugal turntable 1 can effectively avoid forming an air channel of a centrifugal chamber to cause large centrifugal noise.
In a more preferred embodiment, the outer side of the centrifugal turntable 1 is provided with a centrifugal outer cabin 6, a centrifugal motor 61 is arranged in the middle of the centrifugal outer cabin 6, and a magnetic attraction structure 3 and a Hall sensor are arranged at the corresponding position of the bilge of the centrifugal outer cabin 6. Through this kind of setting can guarantee the effective rotation of centrifugal carousel 1, and magnetism is inhaled structure 3 and hall sensor and is not set up on centrifugal carousel 1, can furthest reduce centrifugal carousel 1's weight, can not increase centrifugal carousel 1's weight because of increasing the structure that guarantees centrifugal cup 12 and be in vertical state, in order to realize centrifugal cup 12's vertical state, has just increased the weight of a bit magnetic sheet on centrifugal carousel 1, and this weight is very little, can neglect.
In a more preferred embodiment, a plurality of setting holes 11 of centrifugal cups 12 are arranged on the centrifugal turntable 1, the setting holes 11 are high at the edge and low at the middle bottom, the width of the ellipse is matched with the outer diameter of the centrifugal cup 12 in the upper view, the arrangement is that the centrifugal cup 12 can only rotate along the long side direction of the ellipse, and all magnetic attraction actions only control the rotation of the centrifugal cup 12 in the long side direction.
In a more preferred embodiment, a rotation shaft is provided to the centrifugal cup 12, a shaft hole adapted to the rotation shaft is provided to the installation hole 11, and a pressing block 111 for restricting the rotation shaft of the centrifugal cup 12 to the shaft hole is provided to the installation hole 11. The centrifugal cup 12 can be well stabilized at the position where the hole 11 is provided by providing the pressing block 111.
When the centrifugal tube 7 is required to be transferred into the centrifugal cup 12, the centrifugal turntable 1 is rotated at a slower speed, the centrifugal cup 12 with the first mark is stopped to rotate when the centrifugal cup 12 rotates to the magnetic attraction structure 3, the magnetic attraction structure 3 is started to conduct magnetic attraction action on the centrifugal cup 12, the centrifugal cup 12 is enabled to reach a vertical state, the magnetic attraction structure 3 is stopped after that, the centrifugal turntable 1 is rotated to convey the next centrifugal cup 12 to the position of the magnetic attraction structure 3, and the previous round of action is repeated until 360 degrees of rotation is completed. Or a relatively low-speed rotation can be maintained, and the process of the low-speed rotation does not influence the magnetic attraction action. In the process, after the centrifugal cup 12 with the number one enters the corresponding area of the magnet induction structure 4 to complete induction action, whether the corresponding centrifugal cup 12 is in a vertical state is recorded, after 360 degrees of rotation, whether one round of verification is completed, when all the centrifugal cups 12 are in the vertical state, the centrifugal cup 12 with the number one is moved to the corresponding position of the magnetic attraction structure 3, the magnetic attraction structure 3 is started, in the working state of the magnetic attraction structure 3, the centrifugal tube 7 is sent into the centrifugal cup 12 through an operation opening 51 on a centrifugal cover body, the magnetic attraction structure 3 is stopped, the centrifugal turntable 1 is rotated, the next centrifugal cup 12 is sent into the position of the magnetic attraction structure 3, the previous round of action is repeated, and the centrifugal tube 7 is placed in all the centrifugal cups 12 until 360 degrees of rotation.
Similarly, when it is desired to transfer the centrifuge tube 7 out of the centrifuge cup 12, the operation of placing all the centrifuge cups 12 in the upright position is first completed according to the above-described operation, and after completion, all the centrifuge tubes 7 are removed from the centrifuge cup 12, which is designated by the numeral "one", into the centrifuge cup 12.
While the foregoing embodiments of the present invention have been described in terms of specific embodiments, it will be apparent to those skilled in the art that the foregoing embodiments are merely illustrative of some, but not all, of the present invention, and that other advantages and features of the present invention will be readily apparent to those of ordinary skill in the art from consideration of the specification. The invention may be embodied or applied in other specific forms without conflict, the present embodiments may be controlled by a person of ordinary skill in the art, without any exercise of inventive faculty, to obtain all other embodiments, based on the embodiments of the invention, from which the features of the embodiments described above may be combined.

Claims (13)

1.一种自动化的实现离心杯竖直的离心机,其包括1. An automatic centrifuge for vertical centrifuge cup, comprising: 离心杯,其能发生自竖直状态向远离离心机中心方向的转动,多个离心杯设置在离心转盘上,离心杯内设置离心管;其特征在于,A centrifugal cup can rotate from a vertical state to a direction away from the center of the centrifuge, wherein a plurality of centrifugal cups are arranged on a centrifugal turntable and a centrifugal tube is arranged inside the centrifugal cup; the characteristics are as follows: 磁性结构,为薄片式结构,固定在每个离心杯的底部设置一个磁性结构;The magnetic structure is a thin sheet structure, and a magnetic structure is fixed at the bottom of each centrifugal cup; 磁吸结构,设置一个,且设置在离心机内,磁吸结构的磁吸力量吸引磁性结构发生靠近磁吸结构的磁吸动作,同时带动与磁性结构固定连接的离心杯发生转动,最终离心杯的运动停止状态为离心杯的竖直状态,磁吸结构未设置在离心转盘上;A magnetic attraction structure is provided, and is provided in the centrifuge. The magnetic attraction force of the magnetic attraction structure attracts the magnetic structure to make a magnetic attraction action close to the magnetic attraction structure, and at the same time drives the centrifugal cup fixedly connected to the magnetic structure to rotate. Finally, the movement stop state of the centrifugal cup is the vertical state of the centrifugal cup. The magnetic attraction structure is not provided on the centrifugal turntable; 离心转盘转动带动不同的离心杯经过磁吸结构,磁吸结构吸引每个离心杯底部的磁性结构发生磁吸动作,使得每个经过磁吸结构的离心杯完成磁吸动作达到竖直状态,离心转盘转动360°后使得每个离心杯维持在竖直状态;The centrifugal turntable rotates to drive different centrifugal cups through the magnetic attraction structure. The magnetic attraction structure attracts the magnetic structure at the bottom of each centrifugal cup to produce a magnetic attraction action, so that each centrifugal cup passing through the magnetic attraction structure completes the magnetic attraction action and reaches a vertical state. After the centrifugal turntable rotates 360°, each centrifugal cup is maintained in a vertical state. 在离心机内设置一个磁体感应结构,用于通过能否监测到磁性结构监测离心杯是否处于竖直状态;其仅能够感应到离心杯竖直状态下的磁性结构,当离心杯转动到磁体感应结构感应区域时,且离心杯处于竖直状态下时,磁体感应结构感应到磁性结构,否则不能感应到磁性结构,说明离心杯未处于竖直状态;A magnetic sensing structure is set in the centrifuge to monitor whether the centrifuge cup is in a vertical state by detecting whether the magnetic structure can be detected; it can only sense the magnetic structure of the centrifuge cup in a vertical state. When the centrifuge cup rotates to the sensing area of the magnetic sensing structure and the centrifuge cup is in a vertical state, the magnetic sensing structure senses the magnetic structure. Otherwise, the magnetic structure cannot be sensed, indicating that the centrifuge cup is not in a vertical state. 当离心杯转动到磁体感应结构感应区域后,但离心杯未处于竖直状态下时,磁体感应结构不能感应到磁性结构,则控制离心转盘回转到磁吸结构所在位置再次进行磁吸动作,使得离心杯处在竖直状态,后再次转到磁体感应结构位置;或者,给每个离心杯标号,记录未感应到磁性结构的离心杯的标号,待转动360°完成所有离心杯的感应后,根据记录的未感应到的离心杯的标号,再次进行磁吸动作,再次使得离心杯处于竖直状态,后再通过磁体感应结构进行是否为竖直状态的验证。When the centrifugal cup rotates to the sensing area of the magnetic sensing structure, but the centrifugal cup is not in a vertical state, the magnetic sensing structure cannot sense the magnetic structure, and the centrifugal turntable is controlled to rotate back to the position of the magnetic attraction structure to perform magnetic attraction again, so that the centrifugal cup is in a vertical state, and then rotate to the position of the magnetic sensing structure again; alternatively, label each centrifugal cup, record the number of the centrifugal cup that is not sensed by the magnetic structure, and after rotating 360° to complete the sensing of all centrifugal cups, perform magnetic attraction again according to the recorded number of the centrifugal cup that is not sensed, and then verify whether it is in a vertical state through the magnetic sensing structure. 2.根据权利要求1所述的离心机,其特征在于,在离心杯的垂直调整状态时,控制离心转盘维持小于每秒60°的转动速度,或者当每个离心杯转动到磁吸结构对应位置上方时,停顿0.5—1s。2. The centrifuge according to claim 1 is characterized in that when the centrifugal cup is in a vertical adjustment state, the centrifugal turntable is controlled to maintain a rotation speed of less than 60° per second, or when each centrifugal cup rotates to above the corresponding position of the magnetic attraction structure, it pauses for 0.5-1s. 3.根据权利要求1所述的离心机,其特征在于,当第二次无法感应到离心杯底部的磁性结构时,发出报警信号,停止运行。3. The centrifuge according to claim 1 is characterized in that when the magnetic structure at the bottom of the centrifuge cup cannot be sensed for the second time, an alarm signal is issued and the operation is stopped. 4.根据权利要求1所述的离心机,其特征在于,对所有的离心杯进行标号,控制标号为一的离心杯处在磁吸结构上方,按照程序方向转动360°,依次对离心转盘上的每个离心杯进行磁吸动作,使得离心杯处在竖直状态;当第一个离心完成磁吸动作后,进入到磁体感应结构的感应区域时,触发感应动作,并按照程序转动360°;完成对所有通过磁吸动作后的离心杯的是否为竖直状态的验证,过程中记录未感应到离心杯处于竖直状态的离心杯的标号,待完成首轮360°的验证后;将记录的未感应到处在竖直状态的离心杯再次依次转动到磁吸结构上方再次进行磁吸动作,磁吸动作后再次转动到磁体感应结构的感应区域,再次完成磁吸动作于磁体感应结构的第二轮的360°的转动,最后控制标号为一的离心杯处于磁吸结构上方,并开启磁吸结构。4. The centrifuge according to claim 1 is characterized in that all centrifugal cups are numbered, and the centrifugal cup with the number one is controlled to be above the magnetic attraction structure, rotated 360° according to the program direction, and magnetic attraction is performed on each centrifugal cup on the centrifugal turntable in turn, so that the centrifugal cup is in a vertical state; when the first centrifuge completes the magnetic attraction action and enters the induction area of the magnetic induction structure, the induction action is triggered, and the centrifugal cup is rotated 360° according to the program; the verification of whether all centrifugal cups after the magnetic attraction action are in a vertical state is completed, and the number of the centrifugal cup that is not sensed to be in a vertical state is recorded during the process, and after the first round of 360° verification is completed; the centrifugal cups that are not sensed to be in a vertical state are rotated to the top of the magnetic attraction structure again in turn to perform the magnetic attraction action again, and after the magnetic attraction action, they are rotated to the induction area of the magnetic induction structure again, and the magnetic attraction action is completed again in the second round of 360° rotation of the magnetic induction structure, and finally the centrifugal cup with the number one is controlled to be above the magnetic attraction structure, and the magnetic attraction structure is turned on. 5.根据权利要求1所述的离心机,其特征在于,离心机上设置有离心机盖体,盖体上设置运行操作器械进入离心机内的操作口,磁吸结构设置在操作口所在的离心机位置。5. The centrifuge according to claim 1 is characterized in that a centrifuge cover is provided on the centrifuge, an operating port for operating instruments to enter the centrifuge is provided on the cover, and the magnetic attraction structure is provided at the centrifuge position where the operating port is located. 6.根据权利要求1所述的离心机,其特征在于,按照顺时针或逆时针方向转动离心转盘,磁体感应结构设置在磁吸结构转动方向后的位置,其两者的间隔角度是每两个离心杯间隔角度的倍数。6. The centrifuge according to claim 1 is characterized in that when the centrifugal turntable is rotated clockwise or counterclockwise, the magnetic sensing structure is arranged behind the magnetic attraction structure in the rotation direction, and the spacing angle between the two is a multiple of the spacing angle between every two centrifugal cups. 7.根据权利要求6所述的离心机,其特征在于,磁体感应结构相隔180°设置。7. The centrifuge according to claim 6, characterized in that the magnetic induction structures are arranged 180° apart. 8.根据权利要求1所述的离心机,其特征在于,磁性结构为贴于离心杯底部的磁性片,磁吸结构为电磁吸盘,当磁性结构进入到电磁吸盘上方时,通电进行磁吸动作,磁吸动作结束后断电;磁体感应结构为霍尔感应器。8. The centrifuge according to claim 1 is characterized in that the magnetic structure is a magnetic sheet attached to the bottom of the centrifuge cup, the magnetic attraction structure is an electromagnetic suction cup, when the magnetic structure enters above the electromagnetic suction cup, power is turned on to perform magnetic attraction, and power is turned off after the magnetic attraction action is completed; the magnetic sensing structure is a Hall sensor. 9.根据权利要求8所述的离心机,其特征在于,离心杯内侧底部设置为平面,磁性片为贴附于离心杯内侧底部平面上。9. The centrifuge according to claim 8, characterized in that the inner bottom of the centrifuge cup is set to be a plane, and the magnetic sheet is attached to the inner bottom plane of the centrifuge cup. 10.根据权利要求1所述的离心机,其特征在于,离心转盘为底部为封闭的结构,底部为薄底结构,薄底结构不会对电磁吸盘及霍尔感应器对磁性片的磁吸作用力及感应力量产生干扰。10. The centrifuge according to claim 1 is characterized in that the centrifugal turntable has a closed bottom structure and a thin bottom structure, and the thin bottom structure will not interfere with the magnetic attraction force and induction force of the electromagnetic suction cup and the Hall sensor on the magnetic sheet. 11.根据权利要求10所述的离心机,其特征在于,离心转盘外侧为离心机外舱,离心机外舱中间设置离心电机,在离心机外舱的舱底对应位置设置磁吸结构与霍尔感应器。11. The centrifuge according to claim 10, characterized in that the outer side of the centrifugal turntable is a centrifuge outer cabin, a centrifugal motor is arranged in the middle of the centrifuge outer cabin, and a magnetic attraction structure and a Hall sensor are arranged at corresponding positions on the bottom of the centrifuge outer cabin. 12.根据权利要求10所述的离心机,其特征在于,离心转盘上设置多个离心杯的设置孔,设置孔为边缘高中间低,上视下为椭圆形,椭圆形的宽度与离心杯外径适配。12. The centrifuge according to claim 10, characterized in that a plurality of centrifuge cup setting holes are arranged on the centrifuge turntable, the setting holes are high at the edges and low in the middle, and are elliptical when viewed from above, and the width of the ellipse is adapted to the outer diameter of the centrifuge cup. 13.根据权利要求10所述的离心机,其特征在于,离心杯上设置转轴,设置孔上设置与转轴适配的轴孔,在设置孔上设置将离心杯的转轴限制在轴孔内的压块。13. The centrifuge according to claim 10, characterized in that a rotating shaft is arranged on the centrifugal cup, an axial hole matching the rotating shaft is arranged on the setting hole, and a pressure block is arranged on the setting hole to limit the rotating shaft of the centrifugal cup in the axial hole.
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