CN119901685A - Flow cell and fluid monitoring equipment - Google Patents

Abstract

The application discloses a flow cell and fluid monitoring equipment. The flow cell comprises a body including an inlet, an outlet, an internal passage extending from the inlet to the outlet, and a receiver including a receiving cavity and a first opening through which the receiving cavity and the internal passage communicate, a flow tube disposed in the internal passage, the flow tube defining a fluid flow passage therein, at least a portion of the flow tube being optically transmissive to form an optically transmissive segment disposed opposite the first opening, and a sealing device configured to form a seal between the body and the flow tube to block fluid inflow. The flow cell disclosed by the application can isolate the functional element from fluid in the flow tube, is not in direct contact with the fluid, reduces the requirements on sealing and materials of the functional element and the like, further reduces the cost of the functional element, is convenient for flexible disassembly and assembly between the functional element and the flow cell, and improves the convenience of use.

Description

Flow cell and fluid monitoring device

Technical Field

The application belongs to the technical field of fluid monitoring, and particularly relates to a flow cell and fluid monitoring equipment.

Background

In the industries of hazardous chemical industry, pharmacy and the like, fluid monitoring equipment is generally required to monitor fluids such as liquid, gas and the like on line. Optical characterization technology based on Raman effect and fluorescence has become an important tool for on-line monitoring in the industries of hazardous chemical engineering, pharmacy and the like. In such applications, a flow cell is typically connected to the reaction channel and the progress of the reaction is monitored by a raman probe. Currently, immersion probes are mostly used in the prior art for monitoring, i.e. the probe is inserted into the flow cell such that the probe is in direct contact with or exposed to the fluid in the flow cell. The immersed probe has very high requirements on sealing, materials and the like, so that the overall cost is high, and the probe is not easy to disassemble and assemble.

Disclosure of Invention

The embodiment of the application provides a flow cell and fluid monitoring equipment, which are used for reducing the requirements on functional elements matched with the flow cell to reduce the cost and facilitate the disassembly and assembly of the functional elements.

According to a first aspect of the present application there is provided a flow cell comprising a body comprising an inlet, an outlet, an internal passageway extending from the inlet to the outlet, and a receiver comprising a receiving chamber and a first opening through which the receiving chamber and the internal passageway communicate, a flow tube disposed in the internal passageway, the interior of the flow tube defining a fluid flow passageway, at least a portion of the flow tube being light transmissive to form a light transmissive section, the light transmissive section being disposed opposite the first opening, and sealing means configured to form a seal between the body and the flow tube to block fluid inflow.

Optionally, the flow cell further comprises a reflecting mirror arranged on the body, wherein the receiver and the reflecting mirror are respectively arranged on two opposite sides of the light transmission section along the first direction, so that the reflecting mirror reflects the light rays emitted from the first opening and transmitted through the light transmission section, and the first direction is intersected with the axial direction of the light transmission section.

Optionally, the body further comprises a protruding part, wherein the protruding part is internally provided with a containing cavity, the reflector is arranged in the containing cavity, the inner end of the containing cavity is communicated with the inner channel, the outer end of the containing cavity is sealed by the gland, the inner channel extends along the second direction, the receiving cavity and the containing cavity both extend along the first direction and are respectively positioned at two opposite sides of the inner channel along the first direction, and the first direction and the second direction are intersected.

Optionally, the flow tube extends from the inlet to the outlet and matches the shape of the internal passageway, and the sealing means comprises a first tubular connector connected to the body at the inlet and a first sealing assembly in contact with and sealing against the first tubular connector, the inlet and a first orifice of the flow tube adjacent the inlet.

Optionally, the inner peripheral wall of the inlet is provided with a first step part, the inner peripheral wall of the first tubular connecting piece is provided with a second step part, the first sealing component comprises a first sealing piece, the first sealing piece is provided with a cylinder part and a ring part extending along the circumferential direction of the cylinder part, the cylinder part is inserted between the first step part and the first pipe orifice, the inner peripheral wall of the cylinder part is abutted with the outer pipe wall of the first pipe orifice, the outer peripheral wall of the cylinder part is abutted with the first step part, the first end face of the ring part along the axial direction is abutted with the end face of the inlet, and the second end face of the ring part opposite to the first end face along the axial direction is abutted with the second step part.

Optionally, the inner peripheral wall of the first tubular connecting piece is further provided with a circumferentially extending accommodating groove, the second step part extends radially outwards from a notch of the accommodating groove facing the inlet, and the first sealing assembly further comprises a second sealing piece which is arranged in the accommodating groove and is abutted against the second end face of the ring part and the end face of the first pipe orifice.

Optionally, the first sealing assembly further comprises a third sealing element, the third sealing element is arranged on the first step part, the end face of the barrel part along the axial direction of the barrel part is abutted against the third sealing element, and/or the depth of the accommodating groove along the axial direction is smaller than the thickness of the second sealing element along the axial direction.

Optionally, the receiver further comprises a receiving body and a fixing member, wherein the receiving cavity is formed in the receiving body, the receiving body is provided with a fixing hole penetrating through the peripheral wall of the receiving body in the radial direction, and the fixing member is movably connected to the fixing hole along the radial direction of the receiving body so as to change the length of the fixing member extending into the receiving cavity.

Optionally, the receiver further comprises a receiver body, wherein the receiving cavity is formed in the receiver body, and the inner peripheral wall of the receiver body is provided with a limiting part adjacent to the first opening, wherein the limiting part extends along the circumferential direction of the inner peripheral wall and protrudes inwards from the inner peripheral wall of the receiver body in the radial direction so as to limit the length of the functional element inserted into the receiving cavity.

According to a second aspect of the present application there is also provided a fluid monitoring apparatus comprising a functional element, a fluid input tube, a fluid output tube and a flow cell as provided in any of the embodiments above, the fluid input tube being in fluid connection with an inlet of the flow cell, the fluid output tube being in fluid connection with an outlet of the flow cell, the functional element being connected to the flow cell via a receiving chamber of the flow cell and being configured to emit light through a light transmitting section of the flow tube towards a fluid flow channel within the flow tube.

The flow cell provided by the embodiment of the application comprises a body, a flow pipe and a sealing device. A fluid flow passage is defined within the flow tube to allow fluid flow within the flow tube. The body includes an interior passage extending from an inlet thereof to an outlet thereof, and the flow tube is disposed in the interior passage of the body. The body also includes a receiver including a receiving cavity and a first opening through which the receiving cavity and the internal passageway communicate. The receiving cavity is configured to receive a functional element for monitoring the fluid, the functional element being exposable to the internal passage through the first opening. The flow pipe is provided with a light transmission section which is arranged opposite to the first opening, so that light emitted by the functional element can irradiate the light transmission section through the first opening, and then the light transmission section irradiates fluid inside the flow pipe, so that the purpose of monitoring the fluid is realized conveniently. According to the flow cell provided by the embodiment of the application, fluid flows in the flow tube, and the sealing device can form fluid sealing between the body and the flow tube, so that the fluid in the flow tube is effectively prevented from penetrating into the internal channel and the receiving cavity of the body. That is, there is no fluid in the internal passage of the body and the receiving cavity. After the functional element is connected to the flow cell through the receiving cavity, the functional element is exposed to the internal channel through the first opening, on one hand, the light transmission section can allow the functional element to irradiate fluid in the flow cell so as to realize a fluid monitoring function, on the other hand, the functional element is isolated from the fluid in the flow cell and is not in direct contact with the fluid, the requirements on sealing and materials of the functional element and the like are reduced, the cost of the functional element is further reduced, flexible disassembly and assembly between the functional element and the flow cell are facilitated, and the use convenience is improved.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments of the present application will be briefly described below, and it is obvious that the drawings described below are only some embodiments of the present application, and other drawings may be obtained according to these drawings without inventive effort to a person of ordinary skill in the art.

Fig. 1 is a schematic structural diagram of a flow cell according to an embodiment of the present application.

Fig. 2 is a schematic exploded view of the flow cell of fig. 1.

Fig. 3 is a schematic cross-sectional view of fig. 1 along the direction C-C.

Fig. 4 is a schematic cross-sectional view of the body of the flow cell shown in fig. 1.

Fig. 5 is a schematic side view of the flow cell of fig. 1.

Fig. 6 is a schematic cross-sectional structure along the direction B-B of fig. 5.

Fig. 7 is an enlarged schematic view of the area a of fig. 6.

Fig. 8 is a schematic structural view of a fluid monitoring apparatus according to an embodiment of the present application.

Detailed Description

Features and exemplary embodiments of various aspects of the present application will be described in detail below, and in order to make the objects, technical solutions and advantages of the present application more apparent, the present application will be described in further detail below with reference to the accompanying drawings and the detailed embodiments. It should be understood that the specific embodiments described herein are merely configured to illustrate the application and are not configured to limit the application. It will be apparent to one skilled in the art that the present application may be practiced without some of these specific details. The following description of the embodiments is merely intended to provide a better understanding of the application by showing examples of the application.

It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising" does not exclude the presence of additional identical elements in a process, method, article, or apparatus that comprises the element.

It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The embodiments will be described in detail below with reference to the accompanying drawings.

Fig. 1 is a schematic structural view of a flow cell according to an embodiment of the present application, and fig. 2 is an exploded structural view of the flow cell shown in fig. 1. Referring to fig. 1 and 2, a flow cell 100 according to an embodiment of the present application includes a body 10, a flow tube 20, and a sealing device 30.

Fig. 3 is a schematic cross-sectional view of the flow cell of fig. 1 along the direction C-C, and fig. 4 is a schematic cross-sectional view of the body of the flow cell of fig. 1. Referring to fig. 1 to 4, the body 10 includes an inlet 111, an outlet 121, an internal passage 13, and a receiver 14, the internal passage 13 extending from the inlet 111 to the outlet 121, the receiver 14 including a receiving chamber 141 and a first opening 142, the receiving chamber 141 and the internal passage 13 communicating through the first opening 142. The flow tube 20 is disposed in the internal channel 13, the flow tube 20 defines a fluid flow channel 21 therein, at least a portion of the flow tube 20 is disposed in a light transmissive manner to form a light transmissive section 22, and the light transmissive section 22 is disposed opposite the first opening 142. The sealing device 30 is configured to form a seal between the body 10 and the flow tube 20 to block the inflow of fluid.

The flow cell 100 may receive the sampling fluid through a nozzle of the flow tube 20 adjacent to the inlet 111 and direct the sampling fluid through the flow tube 20 to a nozzle of the flow tube 20 adjacent to the outlet 121.

The body 10 may include a first boss 11 and a second boss 12. The first boss 11 and the second boss 12 are connected, and the interiors of the first boss 11 and the second boss 12 are both formed with hollow passages, and the hollow passages of the first boss 11 and the second boss 12 are connected together to form an interior passage 13. The inlet 111 may be formed at a port of the first boss 11 facing away from the second boss 12, and the outlet 121 may be formed at a port of the second boss 12 facing away from the first boss 11.

The inner channel 13 may extend straight in a predetermined direction, may extend in a bent manner, or may extend in a curved manner.

The receiving chamber 141 may communicate with a central section of the internal passage 13, which is between the inlet 111 and the outlet 121. Alternatively, the receiving chamber 141 may communicate with the inner passage 13 at a very center position in the axial direction thereof.

The flow tube 20 and the body 10 have an interface therebetween, and the sealing device 30 is capable of forming a seal between the interface of the body 10 and the flow tube 20, thereby blocking fluid within the flow tube 20 from flowing into the interface between the body 10 and the flow tube 20.

The light-transmitting section 22 may be a partial section of the flow-through tube 20, and the light-transmitting section 22 may be a middle section of the flow-through tube 20, for example. The first opening 142 is disposed opposite the light-transmitting segment 22. The transparent section 22 may also be the whole section of the flow tube 20, that is, the flow tube 20 is integrally transparent, and the first opening 142 is opposite to any position of the flow tube 20. Illustratively, the flow tube 20 may be entirely transparent.

It is understood that the fluid to which embodiments of the present application relate means a gas, a liquid, or a mixture of a gas and a liquid.

The flow cell 100 provided by the embodiment of the application comprises a body 10, a flow tube 20 and a sealing device 30. The flow tube 20 defines a fluid flow passage 21 therein to allow fluid to flow within the flow tube 20. The body 10 includes an internal passage 13 extending from an inlet 111 thereof to an outlet 121 thereof, and the flow tube 20 is disposed in the internal passage 13 of the body 10. The body 10 further includes a receiver 14, the receiver 14 including a receiving chamber 141 and a first opening 142, the receiving chamber 141 and the internal passage 13 communicating through the first opening 142. The receiving chamber 141 is capable of receiving a functional element for monitoring a fluid, thereby connecting the functional element to the flow cell 100. The functional element may be exposed to the internal channel 13 through the first opening 142. The flow tube 20 has a transparent section 22, and the transparent section 22 is disposed opposite to the first opening 142, so that the light emitted by the functional element can be irradiated to the transparent section 22 through the first opening 142, and then the fluid is irradiated through the transparent section 22 into the flow tube 20, so as to achieve the purpose of monitoring the fluid.

According to the flow cell 100 provided by the embodiment of the application, fluid flows in the flow tube 20, and the sealing device 30 can form fluid seal between the body 10 and the flow tube 20, so that the fluid in the flow tube 20 is effectively prevented from penetrating into the internal channel 13 and the receiving cavity 141 of the body 10. That is, there is no fluid in the internal channel 13 of the body 10 and the receiving cavity 141. After the functional element is connected to the flow cell 100 through the receiving cavity 141, the functional element is exposed to the internal channel 13 through the first opening 142, on one hand, the light transmitting section 22 can allow the functional element to irradiate the fluid in the flow tube 20 so as to realize the fluid monitoring function, on the other hand, the functional element is isolated from the fluid in the flow tube 20 and is not in direct contact with the fluid, so that the requirements on sealing and materials of the functional element are reduced, the cost of the functional element is further reduced, flexible disassembly and assembly between the functional element and the flow cell 100 are facilitated, and the use convenience is improved.

Fig. 5 is a schematic side view of the flow cell of fig. 1, and fig. 6 is a schematic cross-sectional view of fig. 5 along direction B-B. In some embodiments, the flow cell 100 further includes a mirror 40, the mirror 40 is disposed on the body 10, the receiver 14 and the mirror 40 are disposed on two opposite sides of the transparent segment 22 along the first direction X, respectively, such that the mirror 40 reflects the light emitted from the first opening 142 and passing through the transparent segment 22, and the first direction X intersects the axial direction of the transparent segment 22.

Mirror 40 may be a planar mirror, a spherical mirror, or an aspherical mirror.

The first direction X may intersect the axial direction of the light-transmitting segment 22 perpendicularly, or may intersect the axial direction of the light-transmitting segment 22 obliquely at an angle other than 90 degrees.

The receiver 14 is disposed opposite the transparent segment 22 on one side of the transparent segment 22 along the first direction X, and the reflector 40 is disposed opposite the transparent segment 22 on the other side of the transparent segment 22 along the first direction X to allow light emitted from the functional element connected to the receiver 14 to enter the interior of the transparent segment 22 and allow light within the transparent segment 22 to enter the reflector 40.

In the embodiment of the application, the reflector 40 is arranged on the side of the transparent section 22 opposite to the receiver 14, and after the light emitted by the functional element connected to the receiver 14 irradiates the transparent section 22, the reflector 40 can reflect at least part of the light scattered in the transparent section 22, so that the intensity of the light signal which can be received by the functional element is enhanced, and the fluid monitoring effect is further improved.

In some embodiments, the body 10 further includes a protrusion 15, a receiving cavity 151 is defined in the protrusion 15, the reflecting mirror 40 is disposed in the receiving cavity 151, an inner end of the receiving cavity 151 communicates with the inner passage 13, and an outer end of the receiving cavity 151 is closed by the pressing cover 50.

The pressing cover 50 is detachably coupled to the projection 15 to press the reflecting mirror 40, and also to facilitate the disassembly and replacement of the reflecting mirror 40. The connection between the gland 50 and the boss 15 includes, but is not limited to, threaded connection, snap-fit, etc. Illustratively, the exterior of the gland 50 may be provided with external threads and the cavity wall of the receiving cavity 151 may be provided with internal threads, with the end face of the gland 50 being provided with a groove of a letter, cross or other shape for screwing the gland 50 into the boss 15 using a screwing tool.

The embodiment of the application is convenient for assembling the reflecting mirror 40 by arranging the convex part 15 to accommodate the reflecting mirror 40. The pressing cover 50 can press the reflecting mirror 40 from the outer end of the protruding portion 15, preventing the reflecting mirror 40 from falling off or loosening.

In some embodiments, the internal channel 13 extends along the second direction Y, and the receiving chamber 141 and the accommodating chamber 151 each extend along the first direction X and are respectively located at opposite sides of the internal channel 13 along the first direction X, and the first direction X and the second direction Y intersect.

The inner channel 13 may be a channel extending straight in the first direction X, whereby the flow tube 20 may be one tube extending straight from the inlet 111 to the outlet 121, facilitating the processing and assembly of the flow tube 20, and the integrated flow tube 20 does not need to take tightness into account.

The receiving chamber 141 and the receiving chamber 151 may each be a passage extending straight in the second direction Y, thereby facilitating the connection of the functional elements and the assembly of the reflecting mirror 40.

In some embodiments, the flow tube 20 extends from the inlet 111 to the outlet 121 and matches the shape of the internal passageway 13. Illustratively, the flow tube 20 may be a circular tube and the internal passageway 13 may be a cylindrical passageway. The outside diameter of the flow tube 20 is substantially the same as the diameter of the inner channel 13.

Further, the sealing device 30 comprises a first tubular connection 31 and a first sealing assembly 32, the first tubular connection 31 being connected to the body 10 at the inlet 111, the first sealing assembly 32 being in sealing contact with the first tubular connection 31, the inlet 111, and the first nozzle 23 of the flow tube 20 adjacent to the inlet 111.

The central axis of the first tubular connection 31 may extend in the second direction Y, and the central axis of the first tubular connection 31, the central axis of the inner passage 13, and the central axis of the flow tube 20 may coincide with each other.

The connection between the first tubular connection 31 and the body 10 includes, but is not limited to, threaded connection, clamping, welding, etc. Illustratively, the interior of the first tubular connection 31 is provided with internal threads and the outer peripheral wall of the inlet 111 of the body 10 is provided with external threads, the internal threads of the first tubular connection 31 being threadedly connected with the external threads at the inlet 111.

The first seal assembly 32 may be disposed between the first tubular connector 31, the inlet 111 and the first nozzle 23, and when the first tubular connector 31 is connected to the body 10, it is capable of compressing the first seal assembly 32 between the inlet 111 of the body 10 and the first nozzle 23 of the flow tube 20, thereby achieving a fluid-tight seal between the inlet 111 of the body 10 and the first nozzle 23 of the flow tube 20.

Fig. 7 is an enlarged schematic view of the area a of fig. 6. Referring to fig. 2,3 and 7, in some embodiments, the inner circumferential wall of the inlet 111 is provided with a first step 1111 and the inner circumferential wall of the first tubular connection 31 is provided with a second step 311. The first seal assembly 32 includes a first seal 321, the first seal 321 having a cylindrical portion 3211 and a ring portion 3212 extending in a circumferential direction of the cylindrical portion 3211, the cylindrical portion 3211 being interposed between the first stepped portion 1111 and the first nozzle 23, an inner peripheral wall of the cylindrical portion 3211 being in contact with an outer tube wall of the first nozzle 23, an outer peripheral wall of the cylindrical portion 3211 being in contact with the first stepped portion 1111, a first end face 3212a of the ring portion 3212 in an axial direction thereof being in contact with an end face of the inlet 111, and a second end face 3212b of the ring portion 3212 in an axial direction thereof being opposite to the first end face 3212a being in contact with the second stepped portion 311.

The first stepped portion 1111 extends radially outward to form a gap between the first stepped portion 1111 and the outer peripheral wall of the flow tube 20, in which the cylindrical portion 3211 of the first seal 321 is inserted.

Alternatively, the cylindrical portion 3211 is in press-contact with the first stepped portion 1111 and the outer peripheral wall of the flow pipe 20, the first end face 3212a of the ring portion 3212 is in press-contact with the end face of the inlet 111, and the second end face 3212b of the ring portion is in press-contact with the second stepped portion 311, to improve the sealing effect.

The first sealing member 321 may be a cylindrical sealing rubber plug.

By providing the first step 1111, the second step 311 and the first sealing member 321, a sealing interface extending in a bending manner can be formed among the first tubular connecting member 31, the body 10 and the runner pipe 20, and the sealing effect is effectively improved.

In some embodiments, the inner peripheral wall of the first tubular connection 31 is further provided with a circumferentially extending receiving groove 312, the second step 311 extending radially outwardly from a notch of the receiving groove 312 towards the inlet 111. The first seal assembly 32 further includes a second seal 322, where the second seal 322 is disposed in the receiving groove 312 and abuts against the second end face 3212b of the ring portion 3212 and the end face of the first nozzle 23.

The second stepped portion 311 may be located at a side of the receiving groove 312 facing the body 10, that is, the second stepped portion 311 is closer to the body 10 than the receiving groove 312.

Providing the second seal 322 in the receiving slot 312 means that the second seal 322 is at least partially within the receiving slot 312. Illustratively, a partial region of the second seal 322 is within the receiving groove 312 and another partial region is outside of the receiving groove 312. Or the second seal 322 is entirely within the receiving groove 312.

The second seal 322 provided in the accommodation groove 312 is located on a side of the first seal 321 facing away from the body 10 such that a first end face of the second seal 322 in its axial direction abuts against the second end face 3212b of the ring portion 3212 and an end face of the first nozzle 23, and such that a second end face of the second seal 322 in its axial direction abuts against the bottom wall of the accommodation groove 312.

The second seal 322 may be a gasket. The second seal 322 may be an annular gasket, for example.

By arranging the accommodating groove 312 and the second sealing element 322, a plurality of sealing interfaces can be added between the first tubular connecting piece 31 and the first sealing element 321 and between the first tubular connecting piece 31 and the first pipe orifice 23 of the flow pipe 20, so that the sealing effect is further improved.

In some embodiments, the first seal assembly 32 further includes a third seal 323, the third seal 323 is provided on the first step 1111, and an end surface of the barrel portion 3211 in an axial direction thereof abuts against the third seal 323.

The third seal 323 may be a sealing ring. Alternatively, the third seal 323 may be an annular seal ring.

The end surface of the cylindrical portion 3211 in the axial direction thereof faces away from the annular portion 3212. The third sealing member 323 may be disposed at the bottom of the first step 1111, and the cylindrical portion 3211 of the first sealing member 321 may compress the third sealing member 323 between the end surface thereof and the first step 1111, thereby further increasing the sealing interface and improving the sealing effect.

The first sealing member 321, the second sealing member 322 and the third sealing member 323 are combined to form a plurality of sealing interfaces with different shapes and directions at different positions among the first tubular connecting member 31, the body 10 and the runner pipe 20, so that the sealing effect is effectively improved.

In some embodiments, the depth of the receiving groove 312 in the axial direction is less than the thickness of the second seal 322 in the axial direction.

The axial directions of the receiving groove 312 and the second seal 322 may be parallel to the second direction Y.

The embodiment of the present application sets the depth of the receiving groove 312 to be smaller than the thickness of the second sealing member 322 such that the second sealing member 322 is partially received in the receiving groove 312. After the first tubular connecting member 31 is connected to the body 10, the second sealing member 322 can be appropriately pressed, so that the second sealing member 322 is deformed to a certain extent, and the sealing effect is better.

Alternatively, the depth of the receiving groove 312 in the axial direction may be approximately 1/4 to 1/2 of the thickness of the second seal 322 in the axial direction.

In some embodiments, referring to fig. 2, the sealing device 30 further comprises a second tubular connection 33 and a second sealing assembly 34, the second tubular connection 33 being connected to the body 10 at the outlet 121, the second sealing assembly 35 being in contact sealing with the second tubular connection 33, the outlet 121, and the second nozzle 24 of the flow tube 20 adjacent to the outlet 121.

The connection between the second tubular connection 33 and the body 10 includes, but is not limited to, threaded connection, snap-fit, welding, etc. Illustratively, the second tubular connection 33 is internally provided with an internal thread, the outer peripheral wall of the outlet 121 of the body 10 is provided with an external thread, and the internal thread of the second tubular connection 33 is threadedly connected with the external thread at the outlet 121.

The second tubular connector 33 may be disposed between the second tubular connector 33, the outlet 121 and the second nozzle 24, and when the second tubular connector 33 is connected to the body 10, it is capable of compressing the second seal assembly 34 between the outlet 121 of the body 10 and the second nozzle 24 of the flow tube 20, thereby achieving a fluid-tight seal between the outlet 121 of the body 10 and the second nozzle 24 of the flow tube 20.

In some embodiments, the internal passage 13 extends along the second direction Y, the second tubular connection 33 and the first tubular connection 31 are symmetrically disposed about a reference plane perpendicular to the second direction Y, and the second seal assembly 35 and the first seal assembly 32 are symmetrically disposed about the reference plane.

The second tubular connection 33 may have a symmetrical structure to the first tubular connection 31, and the second seal assembly 35 may have a symmetrical structure to the first seal assembly 32, and thus, a detailed description thereof will be omitted.

In some embodiments, the receiver 14 further includes a receiver 143 and a fixture 144, the receiving cavity 141 being formed within the receiver 143. The receiving body 143 is provided with a fixing hole 1431 penetrating a circumferential wall thereof in a radial direction, and the fixing member 144 is movably coupled to the fixing hole 1431 in the radial direction of the receiving body 143 to vary a length thereof extending into the receiving chamber 141.

The exterior of the receiving body 143 may be generally cylindrical or polygonal. The receiving cavity 141 may be a cylindrical cavity to facilitate plugging of the functional element.

The wall of the fixing hole 1431 may be provided with an internal thread, and the section of the fixing member 144 inserted into the fixing hole 1431 is provided with an external thread, and the fixing hole 1431 is in threaded connection with the fixing member 144.

After the functional element is inserted into the receiving cavity 141, the fixing member 144 is abutted against the functional element by rotating the fixing member 144 radially inward, thereby limiting and fixing the functional element. When the functional element needs to be removed, the fixing member 144 is rotated radially outwards, so that the fixing member 144 is separated from the functional element, and the functional element is released, so that the functional element can be smoothly removed from the flow cell 100.

The fixture 144 may include a first section, a second section, and a third section that are connected in sequence. The peripheral wall of the first section is provided with knurling to facilitate user operation, prevent slipping. The peripheral wall of the third section is provided with external threads for threaded connection with the securing bore 1431. The second section is connected between the first section and the third section, which can extend the axial length of the fixture 144 for user operation.

According to the embodiment of the application, the fixing piece 144 and the fixing hole 1431 are arranged, so that the convenience of disassembling and assembling the functional elements is effectively improved.

In some embodiments, the receiver 14 further includes a receiving body 143, and the receiving cavity 141 is formed within the receiving body 143. The inner peripheral wall of the receiving body 143 is provided with a restricting portion 1432 adjacent to the first opening 142, the restricting portion 1432 extending in the circumferential direction of the inner peripheral wall of the receiving body 143 and protruding radially inward from the inner peripheral wall of the receiving body 143 to restrict the length of insertion of the functional element into the receiving cavity 141.

The diameter of the restriction 1432 may be smaller than the diameter of the receiving cavity 141.

The limiting portion 1432 is disposed adjacent to the first opening 142, so that the functional element can be smoothly inserted into the receiving cavity 141 immediately after the functional element is inserted into the receiving cavity 141, and the limiting portion 1432 can prevent the functional element from being inserted further when the functional element is inserted into the inner end of the receiving cavity 141, so as to prevent the functional element from being inserted into the receiving cavity 141 excessively to collide with the flow tube 20.

In some embodiments, the receiver 14 further includes a receiver body 143, the receiving cavity 141 is formed in the receiver body 143, the first opening 142 is formed at one end in the axial direction of the receiver body 143, and the other end in the axial direction of the receiver body 143 is provided with the second opening 145.

The inner peripheral wall of the receiving body 143 is provided with an annular groove 146 adjacent to the second opening 145, the annular groove 146 extends along the circumferential direction of the inner peripheral wall of the receiving body 143 and is recessed radially outward from the inner peripheral wall of the receiving body 143, an annular damping portion is provided in the annular groove 146, and the inner diameter of the annular damping portion is smaller than the inner diameter of the receiving body 143.

Both ends of the receiving cavity 141 may communicate with the first opening 142 and the second opening 145, respectively. The functional element can be inserted into the receiving cavity 141 through the second opening 145.

The annular groove 146 has an accommodating space formed therein, and can provide a mounting portion for the annular damper portion. The annular damping portion is partially accommodated in the annular recess 146, and another portion protrudes radially inwardly from the receiving cavity 141.

The annular damping portion may be an annular structure made of a flexible material. The annular damping portion may be a silicone O-ring or a rubber O-ring, for example.

When the functional element is inserted into the receiving cavity 141, the annular damping part can generate a certain damping effect, so that the functional element is prevented from being inserted too fast to collide with other structures, and the reliability and stability of the connection of the functional element are improved.

According to a second aspect of the present application, embodiments of the present application also provide a fluid monitoring apparatus. Fig. 8 is a schematic structural view of a fluid monitoring apparatus according to an embodiment of the present application. The fluid monitoring apparatus 1000 comprises a functional element 200, a fluid input tube 300, a fluid output tube 400 and a flow cell 100 as provided in any of the embodiments described above. The fluid input tube 300 is in fluid connection with the inlet 111 of the flow cell 100, the fluid output tube 400 is in fluid connection with the outlet 121 of the flow cell 100, the functional element 200 is connected to the flow cell 100 via the receiving chamber 141 of the flow cell 100 and is configured to emit light through the light transmissive section 22 of the flow tube 20 towards the fluid flow channel within the flow tube 20.

After light is emitted through the light-transmitting section 22 of the flow-through tube 20 to the fluid flow channel in the flow-through tube 20, the sample fluid in the fluid flow channel dissipates the heat of the light. The functional element 200 is further configured to receive scattered light from the sampled fluid to monitor the sampled fluid by the received scattered light.

Illustratively, the functional element 200 may be a raman probe. The functional element 200 is capable of emitting light by a laser system or other light source capable of generating a focused beam of light and collecting scattered light formed upon irradiation of the sample fluid with the light.

One end of the fluid input tube 300 and one end of the fluid output tube 400 may be connected to a reaction tube for sampling fluid, so that the reaction progress of the sampled fluid is monitored by the fluid monitoring apparatus 1000. The other end of the fluid input tube 300 may be connected to the first tubular connection 31 and the other end of the fluid output tube 400 may be connected to the second tubular connection 33.

The fluid monitoring apparatus 1000 according to the embodiment of the present application uses fluid through the flow tube 20, and the sealing device 30 can form a fluid seal between the body 10 and the flow tube 20, so that the fluid in the flow tube 20 is effectively prevented from penetrating into the internal channel 13 and the receiving cavity 141 of the body 10. After the functional element 200 is connected to the flow cell 100 through the receiving cavity 141, the functional element 200 is exposed to the internal channel 13 through the first opening 142, on one hand, the light transmitting section 22 can allow the functional element 200 to irradiate the fluid in the flow tube 20 so as to realize the fluid monitoring function, on the other hand, the functional element 200 is isolated from the fluid in the flow tube 20 and is not in direct contact with the fluid, so that the requirements on sealing and materials of the functional element 200 are reduced, the cost of the functional element is further reduced, flexible disassembly and assembly between the functional element 200 and the flow cell 100 are facilitated, and the use convenience is improved.

In the description of embodiments of the present application, the technical terms "first," "second," and the like are used merely to distinguish between different objects and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated, a particular order or a primary or secondary relationship. In the description of the embodiments of the present application, the meaning of "plurality" is two or more unless explicitly defined otherwise.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.

In the description of the embodiment of the present application, the term "and/or" is merely an association relationship describing the association object, and indicates that three relationships may exist, for example, m and/or n, and may indicate that m exists alone, m and n exist together, and n exists alone. In addition, the character "/" herein generally indicates that the front and rear associated objects are an "or" relationship.

In describing embodiments of the present application, the term "plurality" refers to more than two (including two).

In the description of the embodiments of the present application, the orientation or positional relationship indicated by the technical terms "vertical", "horizontal", "top", "bottom", "inside", "outside", "circumferential", etc. are based on the orientation or positional relationship shown in the drawings, and are merely for convenience of describing the embodiments of the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the embodiments of the present application.

In the description of the embodiments of the present application, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "fixed" and the like are to be construed broadly and include, for example, fixed connection, detachable connection, or integral therewith, mechanical connection, electrical connection, direct connection, indirect connection via an intermediary, communication between two elements, or interaction between two elements. The specific meaning of the above terms in the embodiments of the present application will be understood by those of ordinary skill in the art according to specific circumstances.

In the embodiments of the present application, "parallel" includes not only the case of absolute parallelism but also the case of general parallelism of conventional engineering knowledge, and "perpendicular" includes not only the case of absolute perpendicularity but also the case of general perpendicularity of conventional engineering knowledge. Illustratively, the two directions may be considered to be perpendicular by an angle of 85 ° -90 °, and may be considered to be parallel by an angle of 0 ° -5 °.

While the application has been described with reference to certain preferred embodiments, it will be understood by those skilled in the art that various changes and substitutions of equivalents may be made and equivalents will be apparent to those skilled in the art without departing from the scope of the application. Therefore, the protection scope of the application is subject to the protection scope of the claims.

Claims (10)

1. A flow-through cell comprising a substrate and a plurality of cells, characterized by comprising the following steps:

a body comprising an inlet, an outlet, an internal passage extending from the inlet to the outlet, and a receiver comprising a receiving cavity and a first opening through which the receiving cavity and the internal passage communicate;

A flow tube disposed in the internal passage, the flow tube defining a fluid flow passage therein, at least a portion of the flow tube being optically transmissive to form an optically transmissive section disposed opposite the first opening, and

A sealing device configured to form a seal between the body and the flow tube to block fluid inflow.

2. A flow-through cell according to claim 1, characterized in that the flow cell further comprises:

The reflector is arranged on the body, the receiver and the reflector are respectively arranged on two opposite sides of the light transmission section along the first direction, so that the reflector reflects light rays emitted from the first opening and transmitted through the light transmission section, and the first direction is intersected with the axial direction of the light transmission section.

3. A flow-through cell according to claim 2, characterized in that,

The body further comprises a protruding part, a containing cavity is defined in the protruding part, the reflector is arranged in the containing cavity, the inner end of the containing cavity is communicated with the internal channel, and the outer end of the containing cavity is sealed by a gland;

The inner channel extends along a second direction, the receiving cavity and the accommodating cavity extend along the first direction and are respectively positioned at two opposite sides of the inner channel along the first direction, and the first direction and the second direction are intersected.

4. The flow cell according to claim 1, wherein,

The flow pipe extends from the inlet to the outlet and is matched with the shape of the internal channel;

The sealing device includes a first tubular connection connected to the body at the inlet and a first seal assembly in contact seal with the first tubular connection, the inlet, and a first nozzle of the flow tube adjacent the inlet.

5. The flow cell according to claim 4, wherein the flow cell is configured to,

The inner peripheral wall of the inlet is provided with a first step part, and the inner peripheral wall of the first tubular connecting piece is provided with a second step part;

The first seal assembly comprises a first seal, the first seal is provided with a barrel portion and a ring portion extending along the circumferential direction of the barrel portion, the barrel portion is inserted between the first step portion and the first pipe orifice, the inner peripheral wall of the barrel portion is abutted to the outer pipe wall of the first pipe orifice, the outer peripheral wall of the barrel portion is abutted to the first step portion, the first end face of the ring portion along the axial direction of the ring portion is abutted to the end face of the inlet, and the second end face of the ring portion opposite to the first end face along the axial direction of the ring portion is abutted to the second step portion.

6. The flow cell according to claim 5, wherein the flow cell is configured to,

The inner peripheral wall of the first tubular connecting piece is also provided with a circumferentially extending accommodating groove, and the second step part extends radially outwards from a notch of the accommodating groove, which faces the inlet;

the first sealing assembly further comprises a second sealing element which is arranged in the accommodating groove and is abutted against the second end face of the ring part and the end face of the first pipe orifice.

7. The flow cell according to claim 6, wherein,

The first sealing assembly further comprises a third sealing element, the third sealing element is arranged on the first step part, the end face of the cylinder part along the axial direction of the cylinder part is abutted against the third sealing element, and/or

The depth of the accommodating groove along the axial direction is smaller than the thickness of the second sealing piece along the axial direction.

8. The flow cell according to claim 1, wherein,

The receiver also comprises a receiver body and a fixing piece, wherein the receiving cavity is formed in the receiver body, the receiver body is provided with a fixing hole penetrating through the peripheral wall of the receiver body in the radial direction, and the fixing piece is movably connected with the fixing hole along the radial direction of the receiver body so as to change the length of the receiver body extending into the receiving cavity.

9. The flow cell according to claim 1, wherein,

The receiver further comprises a receiving body, the receiving cavity being formed within the receiving body;

The inner peripheral wall of the receiving body is provided with a limiting part adjacent to the first opening, and the limiting part extends along the circumferential direction of the inner peripheral wall and protrudes inwards from the inner peripheral wall of the receiving body in a radial direction.

10. A fluid monitoring apparatus comprising a functional element, a fluid input conduit, a fluid output conduit and a flow cell according to any one of claims 1-9,

The fluid input tube is in fluid connection with an inlet of the flow cell, the fluid output tube is in fluid connection with an outlet of the flow cell, the functional element is connected to the flow cell via a receiving cavity of the flow cell and is configured to emit light through a light transmissive section of the flow tube towards a fluid flow channel within the flow tube.