CN110584693B - Dual-mode imaging method, device and system - Google Patents
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Abstract
本发明提出一种双模态成像方法、装置和系统,应用于双模态成像设备中,双模态成像设备包括:SPECT设备和MR设备,其中,SPECT设备和MR设备设置在电磁屏蔽空间中,该方法包括对SPECT设备的探头进行信号屏蔽;采用屏蔽后的探头采集待检测用户的SPECT信号数据,并采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像。通过本发明能够解决常规由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时能够同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。
The present invention proposes a dual-mode imaging method, device and system, which are applied to dual-mode imaging equipment. The dual-mode imaging equipment includes: SPECT equipment and MR equipment, wherein the SPECT equipment and MR equipment are arranged in an electromagnetic shielding space , the method includes shielding the signal of the probe of the SPECT device; using the shielded probe to collect the SPECT signal data of the user to be detected, and using MR equipment to collect the MR signal data of the user to be detected, and the SPECT signal data and the MR signal data are used for performing Dual modality imaging. The present invention can solve the problem that conventional SPECT equipment with detectors composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and can simultaneously collect signal data during detection for imaging, and improve the quality of the collected signals. Improve the follow-up imaging effect.
Description
技术领域technical field
本发明涉及生物医学成像技术领域,尤其涉及一种双模态成像方法、装置和系统。The invention relates to the technical field of biomedical imaging, in particular to a dual-mode imaging method, device and system.
背景技术Background technique
SPECT(Single-Photon Emission Computed Tomography,单光子发射计算机断层成像术)是一种临床核医学诊断的影像设备,能提供分子水平的功能信息,成像灵敏度高,但分辨率较低,难以精确描绘病变范围。MRI(Magnetic Resonance Imaging,磁共振成像)是一种断层成像,能够利用磁共振现象从待检测用户中获得电磁信号,进行空间编码重建出待检测用户图像,有较高的分辨率,可以得到物质的多种物理特性参数,如质子密度,自旋-晶格驰豫时间T1等。SPECT (Single-Photon Emission Computed Tomography, Single-Photon Emission Computed Tomography) is an imaging device for clinical nuclear medicine diagnosis, which can provide functional information at the molecular level. scope. MRI (Magnetic Resonance Imaging, Magnetic Resonance Imaging) is a kind of tomography, which can use the magnetic resonance phenomenon to obtain electromagnetic signals from the user to be detected, and perform spatial encoding to reconstruct the image of the user to be detected. It has high resolution and can obtain material A variety of physical characteristic parameters, such as proton density, spin-lattice relaxation time T1, etc.
相关技术中,在MR设备工作的环境下,由光电倍增管组成探测器的SPECT设备无法正常运行,导致无法采集SPECT信号数据,导致后续的成像效果不佳。In the related art, in the working environment of MR equipment, the SPECT equipment composed of photomultiplier tubes as a detector cannot operate normally, resulting in the inability to collect SPECT signal data, resulting in poor subsequent imaging effects.
发明内容Contents of the invention
本发明旨在至少在一定程度上解决相关技术中的技术问题之一。The present invention aims to solve one of the technical problems in the related art at least to a certain extent.
为此,本发明的目的在于提出一种双模态成像方法、装置和系统,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的技术问题,并在进行检测时能够同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。For this reason, the object of the present invention is to propose a dual-mode imaging method, device and system, which can solve the technical problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and can detect It can collect signal data at the same time for imaging, improve the quality of the collected signal, and improve the subsequent imaging effect.
为达到上述目的,本发明第一方面实施例提出的双模态成像方法,应用于双模态成像设备中,所述双模态成像设备包括:SPECT设备和MR设备,其中,所述SPECT设备和MR设备设置在电磁屏蔽空间中,所述方法包括:对所述SPECT设备的探头进行信号屏蔽;采用屏蔽后的探头采集待检测用户的SPECT信号数据,并采用所述MR设备采集所述待检测用户的MR信号数据,所述SPECT信号数据和所述MR信号数据用于进行双模态成像。In order to achieve the above purpose, the dual-mode imaging method proposed in the embodiment of the first aspect of the present invention is applied to a dual-mode imaging device, and the dual-mode imaging device includes: a SPECT device and an MR device, wherein the SPECT device and MR equipment are arranged in an electromagnetic shielding space, and the method includes: performing signal shielding on the probe of the SPECT equipment; using the shielded probe to collect SPECT signal data of the user to be detected, and using the MR equipment to collect the data to be detected. The user's MR signal data is detected, and the SPECT signal data and the MR signal data are used for dual-mode imaging.
本发明第一方面实施例提出的双模态成像方法,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时能够同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。The dual-mode imaging method proposed in the embodiment of the first aspect of the present invention shields the signal of the probe of the SPECT device, and uses the shielded probe to collect the SPECT signal data of the user to be detected, and uses the MR device to collect the MR of the user to be detected. Signal data, SPECT signal data and MR signal data are used for dual-mode imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and can be collected simultaneously during detection Signal data for imaging, improve the quality of the collected signal, and improve the effect of subsequent imaging.
为达到上述目的,本发明第二方面实施例提出的双模态成像装置,应用于双模态成像设备中,所述双模态成像设备包括:SPECT设备和MR设备,其中,所述SPECT设备和MR设备设置在电磁屏蔽空间中,所述装置包括:屏蔽模块,用于对所述SPECT设备的探头进行信号屏蔽;采集模块,用于采用屏蔽后的探头采集待检测用户的SPECT信号数据,并采用所述MR设备采集所述待检测用户的MR信号数据,所述SPECT信号数据和所述MR信号数据用于进行双模态成像。In order to achieve the above purpose, the dual-mode imaging device proposed in the embodiment of the second aspect of the present invention is applied to a dual-mode imaging device, and the dual-mode imaging device includes: a SPECT device and an MR device, wherein the SPECT device and the MR equipment are arranged in the electromagnetic shielding space, the device includes: a shielding module, which is used to shield the probe of the SPECT equipment; an acquisition module, which is used to collect the SPECT signal data of the user to be detected by using the shielded probe, The MR device is used to collect MR signal data of the user to be detected, and the SPECT signal data and the MR signal data are used for dual-mode imaging.
本发明第二方面实施例提出的双模态成像装置,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。The dual-mode imaging device proposed in the embodiment of the second aspect of the present invention shields the signal of the probe of the SPECT device, and uses the shielded probe to collect the SPECT signal data of the user to be detected, and uses the MR device to collect the MR of the user to be detected. Signal data, SPECT signal data and MR signal data are used for dual-mode imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and collect signals at the same time during detection Data for imaging, improving the quality of the collected signal, and improving the effect of subsequent imaging.
为达到上述目的,本发明第三方面实施例提出的双模态成像系统,包括:本发明第二方面实施例提出的双模态成像装置。To achieve the above purpose, the dual-mode imaging system provided by the embodiment of the third aspect of the present invention includes: the dual-mode imaging device provided by the embodiment of the second aspect of the present invention.
本发明第三方面实施例提出的双模态成像系统,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。The dual-mode imaging system proposed in the embodiment of the third aspect of the present invention shields the signal of the probe of the SPECT device, and uses the shielded probe to collect the SPECT signal data of the user to be detected, and uses the MR device to collect the MR of the user to be detected. Signal data, SPECT signal data and MR signal data are used for dual-mode imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and collect signals at the same time during detection Data for imaging, improving the quality of the collected signal, and improving the effect of subsequent imaging.
本发明附加的方面和优点将在下面的描述中部分给出,部分将从下面的描述中变得明显,或通过本发明的实践了解到。Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
附图说明Description of drawings
本发明上述的和/或附加的方面和优点从下面结合附图对实施例的描述中将变得明显和容易理解,其中:The above and/or additional aspects and advantages of the present invention will become apparent and easy to understand from the following description of the embodiments in conjunction with the accompanying drawings, wherein:
图1是本发明一实施例提出的双模态成像方法的流程示意图;FIG. 1 is a schematic flow diagram of a dual-mode imaging method proposed by an embodiment of the present invention;
图2是本发明另一实施例提出的双模态成像方法的流程示意图;FIG. 2 is a schematic flowchart of a dual-mode imaging method proposed in another embodiment of the present invention;
图3是本发明另一实施例提出的双模态成像方法的流程示意图;FIG. 3 is a schematic flowchart of a dual-mode imaging method proposed in another embodiment of the present invention;
图4是本发明一实施例提出的双模态成像设备的结构示意图;FIG. 4 is a schematic structural diagram of a dual-mode imaging device proposed by an embodiment of the present invention;
图5是本发明另一实施例提出的双模态成像设备的结构示意图;FIG. 5 is a schematic structural diagram of a dual-mode imaging device proposed in another embodiment of the present invention;
图6是本发明一实施例提出的双模态成像装置的结构示意图;FIG. 6 is a schematic structural diagram of a dual-mode imaging device proposed by an embodiment of the present invention;
图7是本发明另一实施例提出的双模态成像装置的结构示意图。FIG. 7 is a schematic structural diagram of a dual-mode imaging device according to another embodiment of the present invention.
具体实施方式Detailed ways
下面详细描述本发明的实施例,所述实施例的示例在附图中示出,其中自始至终相同或类似的标号表示相同或类似的元件或具有相同或类似功能的元件。下面通过参考附图描述的实施例是示例性的,仅用于解释本发明,而不能理解为对本发明的限制。相反,本发明的实施例包括落入所附加权利要求书的精神和内涵范围内的所有变化、修改和等同物。Embodiments of the present invention are described in detail below, examples of which are shown in the drawings, wherein the same or similar reference numerals designate the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the figures are exemplary only for explaining the present invention and should not be construed as limiting the present invention. On the contrary, the embodiments of the present invention include all changes, modifications and equivalents coming within the spirit and scope of the appended claims.
为解决相关技术中由于低磁场的MR设备的信噪比较低,现有的SPECT设备与MR设备的串联式组合方式,无法实现同时采集信号数据,而在低磁场环境下信号数据的信号质量不佳,影响后续的成像效果不佳的技术问题,本发明实施例提供一种双模态成像方法,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时能够同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。In order to solve the low signal-to-noise ratio of MR equipment with low magnetic field in related technologies, the serial combination of SPECT equipment and MR equipment cannot realize simultaneous acquisition of signal data, and the signal quality of signal data in a low magnetic field environment Not good, affecting the technical problem of poor subsequent imaging effects, the embodiment of the present invention provides a dual-mode imaging method, by shielding the probe of the SPECT device, and using the shielded probe to collect the SPECT signal of the user to be detected data, and the MR signal data of the user to be detected is collected by MR equipment, and the SPECT signal data and MR signal data are used for dual-mode imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot work normally in the MR equipment working environment Operation problems, and can collect signal data at the same time during detection for imaging, improve the quality of the collected signal, and improve the follow-up imaging effect.
图1是本发明一实施例提出的双模态成像方法的流程示意图。FIG. 1 is a schematic flowchart of a dual-mode imaging method proposed by an embodiment of the present invention.
本实施例提出的双模态成像方法应用于双模态成像设备中,双模态成像设备包括:SPECT设备和MR设备,其中,SPECT设备和MR设备设置在电磁屏蔽空间中。The dual-mode imaging method proposed in this embodiment is applied to a dual-mode imaging device, and the dual-mode imaging device includes: a SPECT device and an MR device, wherein the SPECT device and the MR device are arranged in an electromagnetic shielding space.
参见图1,该方法包括:Referring to Figure 1, the method includes:
S101:对SPECT设备的探头进行信号屏蔽。S101: Perform signal shielding on the probe of the SPECT device.
其中,SPECT设备的探头选用对磁场不敏感的半导体材料,可以是CZT探测器,即碲化镉锌晶体探测器,也可是由光电倍增管即PMT组成的探测器,对此不作限制。Among them, the probe of the SPECT device is made of a semiconductor material that is not sensitive to magnetic fields. It can be a CZT detector, that is, a cadmium zinc telluride crystal detector, or a detector composed of a photomultiplier tube, that is, a PMT. There is no limit to this.
在具体执行过程中,在对SPECT设备的探头进行信号屏蔽时,可以采用对磁场不敏感的半导体材料CZT,还可以对SPECT设备中的电子学部分改用无磁电子元器件,和/或增加采用硅钢制成的射频屏蔽罩等,能够有效保证SPECT设备在强磁场环境下正常采集SPECT信号数据,解决了由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的技术问题。In the specific implementation process, when shielding the signal of the probe of the SPECT equipment, the semiconductor material CZT that is not sensitive to the magnetic field can be used, and the electronic part of the SPECT equipment can be replaced with non-magnetic electronic components, and/or increased The radio frequency shielding cover made of silicon steel can effectively ensure the normal acquisition of SPECT signal data by SPECT equipment in a strong magnetic field environment, and solve the technical problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment. .
S102:采用屏蔽后的探头采集待检测用户的SPECT信号数据,并采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像。S102: Use the shielded probe to collect SPECT signal data of the user to be detected, and use MR equipment to collect MR signal data of the user to be detected, and the SPECT signal data and MR signal data are used for dual-mode imaging.
其中,SPECT设备采集到的信号数据,可以被称为SPECT信号数据,MR设备采集到的信号数据,可以被称为MR信号数据。Wherein, the signal data collected by the SPECT device may be called SPECT signal data, and the signal data collected by the MR device may be called MR signal data.
在实际应用的过程中,待检测用户摄入有半衰期适当的放射性同位素药物,该放射性同位素药物达到需要成像的断层位置后,放射性衰变,断层处发出γ光子,SPECT设备的CZT探头可以检测到断层处发出γ光子,可以将检测到的断层处发出γ光子的信息作为SPECT信号数据。In the process of practical application, the user to be tested takes a radioisotope drug with an appropriate half-life. After the radioisotope drug reaches the fault position to be imaged, it radioactively decays, and the fault emits γ photons. The CZT probe of the SPECT device can detect the fault γ photons are emitted at the fault, and the information of γ photons emitted at the detected fault can be used as SPECT signal data.
在实际应用的过程中,对待检测用户施加某种特定频率的射频脉冲,待检测用户体内氢质子受到激励产生磁共振现象,在停止脉冲后,质子在弛豫过程中产生的磁共振信号,可以由MR设备采集该磁共振信号相关的数据,并作为MR信号数据,其中,可产生磁共振的原子核还有硼(B)、碳(C)、氧(O)、氟(F)、磷(P)等,对此不作限制。In the process of practical application, a radio frequency pulse of a specific frequency is applied to the user to be detected, and the hydrogen protons in the body of the user to be detected are excited to produce a magnetic resonance phenomenon. After the pulse is stopped, the magnetic resonance signal generated by the proton during the relaxation process can be The data related to the magnetic resonance signal is collected by the MR equipment and used as the MR signal data. Among them, the atomic nuclei that can generate magnetic resonance include boron (B), carbon (C), oxygen (O), fluorine (F), phosphorus ( P), etc., without limitation.
在具体执行过程中,MR设备可以采用较强磁场的超导MRI,如1.5T~4T,对待检测用户进行检测,并采集MR信号数据,同时SPECT设备采用CZT探头对待检测用户进行检测,采集SPECT信号数据,对由SPECT设备采集到的SPECT信号数据和MR设备采集到的MR信号数据进行相应的图像处理,以实现双模态成像。In the specific implementation process, the MR equipment can use superconducting MRI with a strong magnetic field, such as 1.5T to 4T, to detect the user to be detected and collect MR signal data. At the same time, the SPECT device uses a CZT probe to detect the user to be detected and collect SPECT Signal data, corresponding image processing is performed on the SPECT signal data collected by the SPECT device and the MR signal data collected by the MR device, so as to realize dual-mode imaging.
本实施例中,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时能够同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。In this embodiment, by shielding the probe of the SPECT device, and using the shielded probe to collect the SPECT signal data of the user to be detected, and using the MR device to collect the MR signal data, SPECT signal data and MR signal data of the user to be detected It is used for dual-mode imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and can simultaneously collect signal data for imaging during detection, improving the collected The signal quality can improve the follow-up imaging effect.
图2是本发明另一实施例提出的双模态成像方法的流程示意图。FIG. 2 is a schematic flowchart of a dual-mode imaging method proposed by another embodiment of the present invention.
参见图2,该方法包括:Referring to Figure 2, the method includes:
S201:对SPECT设备的探头进行信号屏蔽。S201: Perform signal shielding on the probe of the SPECT device.
其中,SPECT设备的探头选用对磁场不敏感的半导体材料,可以是CZT探测器,即碲化镉锌晶体探测器,对此不作限制。Wherein, the probe of the SPECT device is made of a semiconductor material that is not sensitive to the magnetic field, and may be a CZT detector, that is, a cadmium zinc telluride crystal detector, without limitation.
在具体执行过程中,在对SPECT设备的探头进行信号屏蔽时,可以采用对磁场不敏感的半导体材料CZT,还可以对SPECT设备中的电子学部分改用无磁电子元器件,和/或增加采用硅钢制成的射频屏蔽罩等,能够有效保证SPECT设备在强磁场环境下正常采集SPECT信号数据,避免了SPECT设备与MR设备之间的信号磁场的干扰。In the specific implementation process, when shielding the signal of the probe of the SPECT equipment, the semiconductor material CZT that is not sensitive to the magnetic field can be used, and the electronic part of the SPECT equipment can be replaced with non-magnetic electronic components, and/or increased The radio frequency shield made of silicon steel can effectively ensure that the SPECT equipment can normally collect SPECT signal data in a strong magnetic field environment, and avoid the interference of the signal magnetic field between the SPECT equipment and the MR equipment.
S202:采用直流电对电磁屏蔽空间中的SPECT设备和MR设备进行供电,且,SPECT设备和MR设备的地线共用。S202: Using direct current to supply power to the SPECT equipment and the MR equipment in the electromagnetic shielding space, and the ground wires of the SPECT equipment and the MR equipment are shared.
在具体执行过程中,可以对SPECT设备与MR设备的电源进行相应的处理,例如可以采用直流电源对其进行供电,且,SPECT设备与MR设备的地线共用,能够避免交流电对MR设备采集信号的干扰,消除MR图像伪影。In the specific execution process, the power supply of SPECT equipment and MR equipment can be processed accordingly, for example, DC power can be used to supply power to them, and the ground wire of SPECT equipment and MR equipment can be shared, which can avoid AC power from collecting signals for MR equipment interference and eliminate MR image artifacts.
S203:对电磁屏蔽空间的磁场均匀性进行调节。S203: Adjust the uniformity of the magnetic field in the electromagnetic shielding space.
在具体执行过程中,电磁屏蔽空间中设置有SPECT设备和MR设备,其中MR设备对电磁屏蔽空间要求严格,SPECT设备可以设置在MR设备的屏蔽空间中。In the specific implementation process, SPECT equipment and MR equipment are installed in the electromagnetic shielding space, and the MR equipment has strict requirements on the electromagnetic shielding space, and the SPECT equipment can be installed in the shielding space of the MR equipment.
本发明实施例中还可以对电磁屏蔽空间中的磁场均匀性进行调节,例如可以在电磁屏蔽空间中放置铁片,用以提高磁场的均匀性,和/或,调整均匀线圈的电流强度,改变局部磁场的变化,从而调整整个磁场的均匀性,通过改善磁场的均匀性,可以有效的提高MR设备采集信号的信噪比和分辨率,提升双模态成像质量。In the embodiment of the present invention, the uniformity of the magnetic field in the electromagnetic shielding space can also be adjusted. For example, an iron sheet can be placed in the electromagnetic shielding space to improve the uniformity of the magnetic field, and/or, adjust the current intensity of the uniform coil to change Changes in the local magnetic field can adjust the uniformity of the entire magnetic field. By improving the uniformity of the magnetic field, the signal-to-noise ratio and resolution of MR equipment acquisition signals can be effectively improved, and the dual-mode imaging quality can be improved.
S204:采用屏蔽后的探头采集待检测用户的SPECT信号数据,并采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像。S204: Use the shielded probe to collect SPECT signal data of the user to be detected, and use MR equipment to collect MR signal data of the user to be detected, and the SPECT signal data and MR signal data are used for dual-mode imaging.
本实施例中,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果,通过采用直流电对电磁屏蔽空间中的SPECT设备和MR设备进行供电,且,SPECT设备和MR设备的地线共用,能够避免交流电对MR设备采集信号的干扰,消除MR图像伪影,通过对电磁屏蔽空间的磁场均匀性进行调节,能够改善磁场的均匀性,可以有效的提高MR设备采集信号的信噪比和分辨率,提升双模态成像质量。In this embodiment, by shielding the probe of the SPECT device, and using the shielded probe to collect the SPECT signal data of the user to be detected, and using the MR device to collect the MR signal data, SPECT signal data and MR signal data of the user to be detected It is used for dual-mode imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and collect signal data at the same time during detection for imaging, improving the collected The signal quality improves the follow-up imaging effect. By using DC power to supply power to the SPECT equipment and MR equipment in the electromagnetic shielding space, and the ground wire of the SPECT equipment and MR equipment is shared, it can avoid the interference of AC power on the acquisition signal of the MR equipment and eliminate the MR equipment. Image artifacts can improve the uniformity of the magnetic field by adjusting the uniformity of the magnetic field in the electromagnetic shielding space, which can effectively improve the signal-to-noise ratio and resolution of the signals collected by the MR equipment, and improve the quality of dual-mode imaging.
图3是本发明另一实施例提出的双模态成像方法的流程示意图。Fig. 3 is a schematic flowchart of a dual-mode imaging method proposed by another embodiment of the present invention.
参见图3,该方法包括:Referring to Figure 3, the method includes:
S301:对SPECT设备的探头内的电子学部分进行信号屏蔽,电子学部分为无磁电子元器件。S301: Perform signal shielding on the electronic part in the probe of the SPECT device, and the electronic part is a non-magnetic electronic component.
其中,SPECT设备中探头内的电子学部分可以为光电倍增管和模拟定位计算电路,光电倍增管的作用是将接收到的微弱的光信号按比例转换为电子并倍增放大,模拟定位计算电路与光电倍增管相连接,其作用是将光电倍增管输出的电脉冲信号转换为确定晶体闪烁点位置信号和γ射线的能量信号。Among them, the electronic part in the probe in SPECT equipment can be a photomultiplier tube and an analog positioning calculation circuit. The photomultiplier tubes are connected, and their function is to convert the electrical pulse signal output by the photomultiplier tubes into signals for determining the position of crystal scintillation points and energy signals of gamma rays.
在具体执行的过程中,对电子学部分的信号屏蔽可以采用硅钢的射频屏蔽罩等设计,该电子学部分的电子元器件采用无磁电子元器件,能够避免MR设备中强磁场对SPECT设备采集信号的干扰。In the specific implementation process, the signal shielding of the electronic part can be designed with silicon steel radio frequency shielding cover, etc. The electronic components of the electronic part use non-magnetic electronic components, which can avoid the strong magnetic field in the MR equipment from affecting the acquisition of the SPECT equipment. signal interference.
S302:采用第一传导板将直流电传输至电磁屏蔽空间中的SPECT设备和MR设备,以进行供电。S302: Using the first conductive plate to transmit the direct current to the SPECT equipment and the MR equipment in the electromagnetic shielding space for power supply.
第一传导板为屏蔽空间传导板,用于将交流电转变为直流电。The first conductive plate is a shielded space conductive plate for converting alternating current into direct current.
在具体执行过程中,可以将SPECT设备和MR设备的供电电源移动到屏蔽空间外,通过设置第一传导板将交流电变为直流电对SPECT设备和MR设备进行供电,且,SPECT设备与MR设备地线共地。In the specific execution process, the power supply of the SPECT equipment and the MR equipment can be moved outside the shielded space, and the AC power can be changed into a DC power supply for the SPECT equipment and the MR equipment by setting the first conductive plate, and the ground of the SPECT equipment and the MR equipment common ground.
具体地,考虑MR射频信号对开关电源,线性电源等电源器件的影响,将其电源器件拆除移到屏蔽空间外,在通过屏蔽空间传导板进行直流供电,能够隔绝MR设备中射频信号对SPECT设备和MR设备相关联的电源器件的信号干扰。Specifically, considering the impact of MR radio frequency signals on power devices such as switching power supplies and linear power supplies, remove the power devices and move them outside the shielded space, and provide DC power supply through the conductive plate in the shielded space, which can isolate the radio frequency signal in the MR equipment from affecting the SPECT equipment. Signal interference of power supply devices associated with MR equipment.
S303:采用第二传导板将探头采集到的SPECT信号数据传输至信号输出器件,以采用信号输出器件输出SPECT信号数据。S303: Using the second conductive plate to transmit the SPECT signal data collected by the probe to the signal output device, so that the signal output device outputs the SPECT signal data.
第二传导板可以用于将SPECT设备探针采集到的SPECT信号数据传输到成像计算机中。The second conductive plate can be used to transmit the SPECT signal data collected by the probe of the SPECT device to the imaging computer.
信号输出器件例如为交换机,和/或光纤转换盒。The signal output device is, for example, a switch and/or a fiber conversion box.
在具体执行过程中,将SPECT设备中的输出信号线改为光纤输出,将交换机和光纤转换盒供电部分移动到屏蔽空间外,通过第二传导板,将光信号输出到交换机,和/或光纤转换盒中,能够提高SPECT设备信号输出的稳定性和准确性。In the specific implementation process, the output signal line in the SPECT device is changed to optical fiber output, the power supply part of the switch and the optical fiber conversion box is moved outside the shielded space, and the optical signal is output to the switch and/or optical fiber through the second conductive plate In the conversion box, the stability and accuracy of the signal output of the SPECT equipment can be improved.
本发明实施例中,SPECT设备和MR设备可以以前后式组合方式进行组合,参见图4,或者,也可以以嵌入式方式进行组合,参见图5。In the embodiment of the present invention, the SPECT device and the MR device can be combined in a front-to-back combination, see FIG. 4 , or they can also be combined in an embedded mode, see FIG. 5 .
图4中,前后组合式SPECT/MR设备40,包括扫描床41和扫描装置42,其中,扫描床41设计为双层床结构,上层床板411和下层床板412,扫描装置42包括SPECT设备421和MRI设备422,SPECT设备421与MRI设备422前后串联,对于前后位置不作限制,在具体使用过程中,上层床板411承载患者进行SPECT设备421的扫描,并在下层床板412伸出后搭接在辅助支撑装置423时,上层床板411伸出,在MRI设备422中进行扫描,得到SPECT设备和MR设备的融合成像,能够减少SPECT/MR设备40的空间占用面积,降低建造成本。In Fig. 4, front and rear combined SPECT/
图5中,嵌入式SPECT/MR设备50,包括MRI设备51和SPECT设备52,SPECT设备52设置在MRI设备51中,其中,SPECT设备52采用全环设计,并采用多孔准直器进行数据信息的采集,能够实现对患者进行双模态一体同步或异步成像。In Fig. 5, embedded SPECT/MR equipment 50 comprises
本发明实施例中,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果,通过采用直流电对电磁屏蔽空间中的SPECT设备和MR设备进行供电,且,SPECT设备和MR设备的地线共用,能够避免交流电对MR设备采集信号的干扰,消除MR图像伪影,通过对电磁屏蔽空间的磁场均匀性进行调节,可以有效的提高MR设备采集信号的信噪比和分辨率,提升双模态成像质量,通过对SPECT设备的探头内的电子学部分进行信号屏蔽,能够避免MR设备中强磁场对SPECT设备采集信号的干扰,通过采用第一传导板将直流电传输至电磁屏蔽空间中的SPECT设备和MR设备,以进行供电,能够隔绝MR设备中射频信号对SPECT设备和MR设备相关联的电源器件的信号干扰,通过采用第二传导板将探头采集到的SPECT信号数据传输至信号输出器件,以采用信号输出器件输出SPECT信号数据,能够提高SPECT设备信号输出的稳定性和准确性,通过对SPECT设备和MR设备以前后式组合方式进行组合,或,以嵌入式方式进行组合,能够减少SPECT/MR设备40的空间占用面积,降低建造成本,实现对患者进行双模态一体同步或异步成像。In the embodiment of the present invention, by shielding the probe of the SPECT device, and using the shielded probe to collect the SPECT signal data of the user to be detected, and using the MR device to collect the MR signal data of the user to be detected, the SPECT signal data and the MR signal The data is used for dual-modal imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and simultaneously collect signal data during detection for imaging, improving the collected The signal quality of the signal can be improved, and the follow-up imaging effect can be improved. By using DC power to supply power to the SPECT equipment and MR equipment in the electromagnetic shielding space, and the ground wire of the SPECT equipment and the MR equipment is shared, it can avoid the interference of the AC power on the acquisition signal of the MR equipment, and eliminate MR image artifacts, by adjusting the uniformity of the magnetic field in the electromagnetic shielding space, can effectively improve the signal-to-noise ratio and resolution of MR equipment acquisition signals, and improve the quality of dual-mode imaging. Part of the signal shielding can avoid the interference of the strong magnetic field in the MR equipment on the signal collected by the SPECT equipment. By using the first conductive plate to transmit the direct current to the SPECT equipment and MR equipment in the electromagnetic shielding space for power supply, it can isolate the MR equipment. The RF signal interferes with the signal of the power supply device associated with SPECT equipment and MR equipment. By using the second conductive plate to transmit the SPECT signal data collected by the probe to the signal output device, the SPECT signal data can be output by the signal output device, which can improve the SPECT The stability and accuracy of the signal output of the equipment can reduce the space occupation area of the SPECT/
图6是本发明一实施例提出的双模态成像装置的结构示意图。FIG. 6 is a schematic structural diagram of a dual-mode imaging device proposed by an embodiment of the present invention.
参见图6,该装置600包括:Referring to Figure 6, the
屏蔽模块601,用于对SPECT设备的探头进行信号屏蔽;A
采集模块602,用于采用屏蔽后的探头采集待检测用户的SPECT信号数据,并采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像。The
可选地,一些实施例中,屏蔽模块601,具体用于:Optionally, in some embodiments, the
对SPECT设备的探头内的电子学部分进行信号屏蔽,电子学部分为无磁电子元器件。The electronic part in the probe of the SPECT equipment is signal-shielded, and the electronic part is a non-magnetic electronic component.
可选地,一些实施例中,参见图7,双模态成像装置600,还包括:Optionally, in some embodiments, referring to FIG. 7, the dual-
供电模块603,用于采用直流电对电磁屏蔽空间中的SPECT设备和MR设备进行供电,且,SPECT设备和MR设备的地线共用。The
可选地,一些实施例中,SPECT设备和MR设备具有相关联的电源器件,电源器件设置在电磁屏蔽空间的外部,其中,供电模块603,具体用于:Optionally, in some embodiments, the SPECT device and the MR device have associated power supply devices, and the power supply devices are arranged outside the electromagnetic shielding space, wherein the
采用第一传导板将直流电传输至电磁屏蔽空间中的SPECT设备和MR设备,以进行供电。The first conductive plate is used to transmit the direct current to the SPECT equipment and the MR equipment in the electromagnetic shielding space for power supply.
可选地,一些实施例中,参见图7,SPECT设备具有关联的信号输出器件,信号输出器件设置在电磁屏蔽空间的外部,其中,双模态成像装置,还包括:Optionally, in some embodiments, referring to FIG. 7, the SPECT device has an associated signal output device, and the signal output device is arranged outside the electromagnetic shielding space, wherein the dual-mode imaging device further includes:
输出模块604,用于采用第二传导板将探头采集到的SPECT信号数据传输至信号输出器件,以采用信号输出器件输出SPECT信号数据。The
可选地,一些实施例中,参见图7,双模态成像装置600,还包括:Optionally, in some embodiments, referring to FIG. 7, the dual-
调节模块605,用于对电磁屏蔽空间的磁场均匀性进行调节。The
可选地,一些实施例中,SPECT设备和MR设备以前后式组合方式进行组合,或者,SPECT设备和MR设备以嵌入式组合方式进行组合。Optionally, in some embodiments, the SPECT device and the MR device are combined in a back-and-forth combination, or the SPECT device and the MR device are combined in an embedded combination.
需要说明的是,上述图1-图3对双模态成像方法的解释说明也适用于该双模态成像装置600,其实现原理类似,此处不在赘述。It should be noted that the above explanations of the dual-mode imaging method in FIGS. 1-3 are also applicable to the dual-
本发明实施例中,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。In the embodiment of the present invention, by shielding the probe of the SPECT device, and using the shielded probe to collect the SPECT signal data of the user to be detected, and using the MR device to collect the MR signal data of the user to be detected, the SPECT signal data and the MR signal The data is used for dual-modal imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and simultaneously collect signal data during detection for imaging, improving the collected The signal quality can improve the follow-up imaging effect.
为实现上述实施例,本发明提出一种双模态成像系统,包括图4-图5的双模态成像设备,实现图1-图3的双模态成像方法,其实现原理类似,此处不在赘述。In order to realize the above-mentioned embodiments, the present invention proposes a dual-mode imaging system, which includes the dual-mode imaging device shown in Figure 4-Figure 5, and implements the dual-mode imaging method shown in Figure 1-Figure 3, and its realization principle is similar, here I won't go into details.
本发明实施例中,通过对SPECT设备的探头进行信号屏蔽,并采用屏蔽后的探头采集待检测用户的SPECT信号数据,以及采用MR设备采集待检测用户的MR信号数据,SPECT信号数据和MR信号数据用于进行双模态成像,能够解决由光电倍增管组成探测器的SPECT设备无法在MR设备工作环境下正常运行的问题,并在进行检测时同时采集信号数据,以进行成像,提升所采集的信号质量,提升后续成像效果。In the embodiment of the present invention, by shielding the probe of the SPECT device, and using the shielded probe to collect the SPECT signal data of the user to be detected, and using the MR device to collect the MR signal data of the user to be detected, the SPECT signal data and the MR signal The data is used for dual-modal imaging, which can solve the problem that the SPECT equipment composed of photomultiplier tubes cannot operate normally in the working environment of MR equipment, and simultaneously collect signal data during detection for imaging, improving the collected The signal quality can improve the follow-up imaging effect.
需要说明的是,在本发明的描述中,术语“第一”、“第二”等仅用于描述目的,而不能理解为指示或暗示相对重要性。此外,在本发明的描述中,除非另有说明,“多个”的含义是两个或两个以上。It should be noted that, in the description of the present invention, the terms "first", "second" and so on are only used for description purposes, and should not be understood as indicating or implying relative importance. In addition, in the description of the present invention, unless otherwise specified, "plurality" means two or more.
流程图中或在此以其他方式描述的任何过程或方法描述可以被理解为,表示包括一个或更多个用于实现特定逻辑功能或过程的步骤的可执行指令的代码的模块、片段或部分,并且本发明的优选实施方式的范围包括另外的实现,其中可以不按所示出或讨论的顺序,包括根据所涉及的功能按基本同时的方式或按相反的顺序,来执行功能,这应被本发明的实施例所属技术领域的技术人员所理解。Any process or method descriptions in flowcharts or otherwise described herein may be understood to represent modules, segments or portions of code comprising one or more executable instructions for implementing specific logical functions or steps of the process , and the scope of preferred embodiments of the invention includes alternative implementations in which functions may be performed out of the order shown or discussed, including substantially concurrently or in reverse order depending on the functions involved, which shall It is understood by those skilled in the art to which the embodiments of the present invention pertain.
应当理解,本发明的各部分可以用硬件、软件、固件或它们的组合来实现。在上述实施方式中,多个步骤或方法可以用存储在存储器中且由合适的指令执行系统执行的软件或固件来实现。例如,如果用硬件来实现,和在另一实施方式中一样,可用本领域公知的下列技术中的任一项或他们的组合来实现:具有用于对数据信号实现逻辑功能的逻辑门电路的离散逻辑电路,具有合适的组合逻辑门电路的专用集成电路,可编程门阵列(PGA),现场可编程门阵列(FPGA)等。It should be understood that various parts of the present invention can be realized by hardware, software, firmware or their combination. In the embodiments described above, various steps or methods may be implemented by software or firmware stored in memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, it can be implemented by any one or combination of the following techniques known in the art: Discrete logic circuits, ASICs with suitable combinational logic gates, programmable gate arrays (PGAs), field programmable gate arrays (FPGAs), etc.
本技术领域的普通技术人员可以理解实现上述实施例方法携带的全部或部分步骤是可以通过程序来指令相关的硬件完成,所述的程序可以存储于一种计算机可读存储介质中,该程序在执行时,包括方法实施例的步骤之一或其组合。Those of ordinary skill in the art can understand that all or part of the steps carried by the methods of the above embodiments can be completed by instructing related hardware through a program, and the program can be stored in a computer-readable storage medium. During execution, one or a combination of the steps of the method embodiments is included.
此外,在本发明各个实施例中的各功能单元可以集成在一个处理模块中,也可以是各个单元单独物理存在,也可以两个或两个以上单元集成在一个模块中。上述集成的模块既可以采用硬件的形式实现,也可以采用软件功能模块的形式实现。所述集成的模块如果以软件功能模块的形式实现并作为独立的产品销售或使用时,也可以存储在一个计算机可读取存储介质中。In addition, each functional unit in each embodiment of the present invention may be integrated into one processing module, each unit may exist separately physically, or two or more units may be integrated into one module. The above-mentioned integrated modules can be implemented in the form of hardware or in the form of software function modules. If the integrated modules are realized in the form of software function modules and sold or used as independent products, they can also be stored in a computer-readable storage medium.
上述提到的存储介质可以是只读存储器,磁盘或光盘等。The storage medium mentioned above may be a read-only memory, a magnetic disk or an optical disk, and the like.
在本说明书的描述中,参考术语“一个实施例”、“一些实施例”、“示例”、“具体示例”、或“一些示例”等的描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本发明的至少一个实施例或示例中。在本说明书中,对上述术语的示意性表述不一定指的是相同的实施例或示例。而且,描述的具体特征、结构、材料或者特点可以在任何的一个或多个实施例或示例中以合适的方式结合。In the description of this specification, descriptions referring to the terms "one embodiment", "some embodiments", "example", "specific examples", or "some examples" mean that specific features described in connection with the embodiment or example , structure, material or characteristic is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
尽管上面已经示出和描述了本发明的实施例,可以理解的是,上述实施例是示例性的,不能理解为对本发明的限制,本领域的普通技术人员在本发明的范围内可以对上述实施例进行变化、修改、替换和变型。Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and should not be construed as limiting the present invention, those skilled in the art can make the above-mentioned The embodiments are subject to changes, modifications, substitutions and variations.
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