CN111175091B - Multi-channel micro-quantification system for blood cell analyzer - Google Patents
Multi-channel micro-quantification system for blood cell analyzer Download PDFInfo
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- CN111175091B CN111175091B CN202010186586.0A CN202010186586A CN111175091B CN 111175091 B CN111175091 B CN 111175091B CN 202010186586 A CN202010186586 A CN 202010186586A CN 111175091 B CN111175091 B CN 111175091B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/18—Devices for withdrawing samples in the liquid or fluent state with provision for splitting samples into portions
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
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Abstract
本发明公开了一种血细胞分析仪多通道微量定量系统，包括陶瓷分血阀前盖、陶瓷分流片、陶瓷分血阀后盖、旋转阀片机构和五通道微量定量分血阀，所述陶瓷分血阀前盖与所述陶瓷分流片转动连接，所述陶瓷分血阀后盖与所述陶瓷分流片转动连接，并位于远离所述陶瓷分血阀前盖一侧，所述旋转阀片机构与所述陶瓷分血阀前盖固定连接，所述五通道微量定量分血阀与所述陶瓷分血阀前盖、所述陶瓷分流片和所述陶瓷分血阀后盖固定连接，并贯穿所述陶瓷分血阀前盖、所述陶瓷分流片和所述陶瓷分血阀后盖，其中，所述五通道微量定量分血阀包括5个不同的通道，呈圆形阵列形式排列，增加检测种类且缩短检测时间。
The present invention discloses a multi-channel micro-quantitative system for a blood cell analyzer, comprising a ceramic blood separation valve front cover, a ceramic shunt plate, a ceramic blood separation valve rear cover, a rotary valve plate mechanism and a five-channel micro-quantitative blood separation valve, wherein the ceramic blood separation valve front cover is rotatably connected to the ceramic shunt plate, the ceramic blood separation valve rear cover is rotatably connected to the ceramic shunt plate and is located on a side away from the ceramic blood separation valve front cover, the rotary valve plate mechanism is fixedly connected to the ceramic blood separation valve front cover, the five-channel micro-quantitative blood separation valve is fixedly connected to the ceramic blood separation valve front cover, the ceramic shunt plate and the ceramic blood separation valve rear cover, and penetrates the ceramic blood separation valve front cover, the ceramic shunt plate and the ceramic blood separation valve rear cover, wherein the five-channel micro-quantitative blood separation valve comprises 5 different channels arranged in a circular array, thereby increasing the types of detection and shortening the detection time.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a multichannel micro quantitative system of a blood cell analyzer.
Background
The main components in human blood include white blood cells, red blood cells, platelets and the like, wherein the white blood cells are divided into five types of white blood cells, such as lymphocytes, monocytes, basophils, neutrophils and eosinophils, the blood routine examination in a hospital is to count the cells in the blood and further provide information support for the next medical treatment, which is routine and most common five classification, so that the medical unit is more and more urgent in terms of automation of blood detection equipment, speed and detection projects, detection results are required to be completed in a short time, detection is required to be completed in a plurality of detection channels at the same time, therefore, multiple sections of blood are required to be sucked and distributed to different channels according to different volumes for detection, the existing five classification instruments are mostly sucked and sampled according to WBC, RBC and WOC channels, the types are relatively less and single, and the corresponding detection time is also increased.
Disclosure of Invention
The invention aims to provide a multichannel micro quantitative system of a blood cell analyzer, which increases detection types and shortens detection time.
In order to achieve the above purpose, the multichannel micro quantitative system of the blood cell analyzer comprises a ceramic blood separating valve front cover, a ceramic flow dividing plate, a ceramic blood separating valve rear cover, a rotary valve plate mechanism and a five-channel micro quantitative blood separating valve, wherein the ceramic blood separating valve front cover is rotationally connected with the ceramic flow dividing plate and is positioned on one side of the ceramic flow dividing plate, the ceramic blood separating valve rear cover is rotationally connected with the ceramic flow dividing plate and is positioned on one side far from the ceramic blood separating valve front cover, the rotary valve plate mechanism is fixedly connected with the ceramic blood separating valve front cover and is positioned on one side far from the ceramic flow dividing plate, and the five-channel micro quantitative blood separating valve is fixedly connected with the ceramic blood separating valve front cover, the ceramic flow dividing plate and the ceramic blood separating valve rear cover and penetrates through the ceramic blood separating valve front cover, the ceramic flow dividing plate and the ceramic blood separating valve rear cover.
The five-channel micro quantitative blood separating valve comprises a WBC channel, a RBC channel, a WOC channel, a RET channel and an NRBC channel, wherein the WBC channel, the RBC channel, the WOC channel, the RET channel and the NRBC channel are fixedly connected with the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover, penetrate through the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover, and are arranged in a circular array mode.
The inlet of the WOC channel and the RET channel, the outlet of the WOC channel and the outlet of the NRBC channel penetrate through the ceramic blood separating valve front cover, and the inlet of the WOC channel and the RET channel, the outlet of the WOC channel and the outlet of the NRBC channel penetrate through the ceramic blood separating valve rear cover.
The multichannel micro quantitative system of the blood cell analyzer further comprises a sample channel, wherein the sample channel is fixedly connected with the front cover of the ceramic blood separating valve and penetrates through the front cover of the ceramic blood separating valve.
The multichannel micro quantitative system of the blood cell analyzer further comprises a sampling quantitative sensor, wherein the sampling quantitative sensor is fixedly connected with the sample channel and is positioned at one side far away from the front cover of the ceramic blood separating valve.
The multichannel micro quantitative system of the blood cell analyzer further comprises a liquid path sensor, wherein the liquid path sensor is fixedly connected with the sample channel and is positioned at one side of the inlet of the sample channel and one side of the outlet of the sample channel.
The multichannel micro quantitative system of the blood cell analyzer further comprises a limiting block, wherein the limiting block is fixedly connected with the ceramic flow dividing sheet, is rotationally connected with the ceramic blood dividing valve front cover and the ceramic blood dividing valve rear cover, and is positioned on one side of the ceramic blood dividing valve front cover, the ceramic flow dividing sheet and the ceramic blood dividing valve rear cover.
The ceramic blood separating valve front cover and the ceramic blood separating valve rear cover are provided with chamfer angles, and the chamfer angles are positioned at the joints of the ceramic blood separating valve front cover and the ceramic blood separating valve rear cover and the ceramic flow dividing sheets.
The multichannel micro quantitative system of the blood cell analyzer comprises a ceramic blood separating valve front cover, a ceramic flow dividing sheet, a ceramic blood separating valve rear cover, a rotary valve sheet mechanism and a five-channel micro quantitative blood separating valve, wherein the ceramic blood separating valve front cover is rotationally connected with the ceramic flow dividing sheet and is positioned on one side of the ceramic flow dividing sheet, the ceramic blood separating valve rear cover is rotationally connected with the ceramic flow dividing sheet and is positioned on one side far from the ceramic blood separating valve front cover, the rotary valve sheet mechanism is fixedly connected with the ceramic blood separating valve front cover and is positioned on one side far from the ceramic flow dividing sheet, and the five-channel micro quantitative blood separating valve is fixedly connected with the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover and penetrates through the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover, wherein the five-channel micro quantitative blood separating valve comprises 5 different channels which are arrayed in a circular array mode, and the detection time is increased and shortened.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram showing a non-rotating structure of a multichannel micro quantitative system of a blood cell analyzer.
Fig. 2 is a schematic diagram of the structure of fig. 1 after rotation provided by the present invention.
Fig. 3 is a schematic structural view of a front cover of the ceramic blood separating valve provided by the invention.
Fig. 4 is a schematic structural view of a rear cover of the ceramic blood separating valve provided by the invention.
Fig. 5 is a schematic diagram of the structure of the chamfer of the blood separating valve provided by the invention.
1-Ceramic blood separating valve front cover, 2-ceramic flow dividing sheet, 3-ceramic blood separating valve back cover, 4-rotary valve sheet mechanism, 5-five-channel micro quantitative blood separating valve, 51-WBC channel, 52-RBC channel, 53-WOC channel, 54-RET channel, 55-NRBC channel, 511-WBC channel inlet, 512-WBC channel outlet, 521-RBC channel inlet, 522-RBC channel outlet, 531-WOC channel inlet, 532-WOC channel outlet, 541-RET channel inlet, 542-RET channel outlet, 551-NRBC channel inlet, 552-NRBC channel outlet, 6-sample channel, 61-sample channel inlet, 62-sample channel outlet, 7-sampling quantitative sensor, 8-liquid path sensor, 9-stopper, 10-chamfer angle.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative and intended to explain the present invention and should not be construed as limiting the invention.
In the description of the present invention, it should be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the present invention and simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present invention. Furthermore, in the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.
Referring to fig. 1 and 2, the multichannel micro quantitative system of the present invention includes a ceramic blood separating valve front cover 1, a ceramic blood separating plate 2, a ceramic blood separating valve rear cover 3, a rotary valve plate mechanism 4 and a five-channel micro quantitative blood separating valve 5, wherein the ceramic blood separating valve front cover 1 is rotatably connected with the ceramic blood separating plate 2 and is located at one side of the ceramic blood separating plate 2, the ceramic blood separating valve rear cover 3 is rotatably connected with the ceramic blood separating plate 2 and is located at one side far from the ceramic blood separating valve front cover 1, the rotary valve plate mechanism 4 is fixedly connected with the ceramic blood separating valve front cover 1 and is located at one side far from the ceramic blood separating plate 2, and the five-channel micro quantitative blood separating valve 5 is fixedly connected with the ceramic blood separating valve front cover 1, the ceramic blood separating plate 2 and the ceramic blood separating valve rear cover 3 and penetrates through the ceramic blood separating valve front cover 1, the ceramic blood separating plate 2 and the ceramic blood separating valve rear cover 3.
In this embodiment, the multichannel micro quantitative system for a blood cell analyzer comprises a ceramic blood separating valve front cover 1, a ceramic flow dividing plate 2, a ceramic blood separating valve rear cover 3, a rotary valve plate mechanism 4 and a five-channel micro quantitative blood separating valve 5, wherein the ceramic blood separating valve front cover 1is rotationally connected with the ceramic flow dividing plate 2 and is positioned at one side of the ceramic flow dividing plate 2, the ceramic blood separating valve rear cover 3 is rotationally connected with the ceramic flow dividing plate 2 and is positioned at one side far from the ceramic blood separating valve front cover 1, the rotary valve plate mechanism 4 is fixedly connected with the ceramic blood separating valve front cover 1 and is positioned at one side far from the ceramic flow dividing plate 2, the five-channel micro quantitative blood separating valve 5 is fixedly connected with the ceramic blood separating valve front cover 1, the ceramic flow dividing plate 2 and the ceramic blood separating valve rear cover 3, the five-channel micro quantitative blood separating valve 5 consists of 5 channels, the blood separating valve consisting of the ceramic blood separating valve front cover 1, the ceramic blood separating sheet 2 and the ceramic blood separating valve rear cover 3 is used for carrying out accurate quantitative separation on a whole blood sample through relative selective movement by utilizing the rotary valve sheet mechanism 4, the separated blood sample is separated into different independent reaction tanks to complete detection, the whole micro quantitative system is firstly subjected to sample suction by a micro injector, the ceramic blood separating valve front cover 1 and the ceramic blood separating valve rear cover 3 are respectively driven to rotate anticlockwise by the rotary valve sheet mechanism 4 by rotating the ceramic blood separating valve front cover 1, the ceramic blood separating valve rear cover 3 is selected clockwise, the middle ceramic blood separating sheet 2 is not moved, the ceramic blood separating valve front cover 1 and the notch above the ceramic blood separating valve rear cover 3 rotate to a specific position, a sample which is connected into a channel before is cut into five independent channels, blood quantification of the five channels can be finished instantaneously, the sample stored in the flow dividing block and the sample of the three bent steel pipes are driven into a certain amount of diluent to form mixed liquid, the mixed liquid is respectively pressurized and circulated into corresponding reaction cups for reaction counting, after sample separation is finished, the rotary valve plate mechanism 4 drives the ceramic blood separating valve front cover 1 to rotate clockwise, the ceramic blood separating valve rear cover 3 rotates anticlockwise, the ceramic blood separating plate 2 still keeps still to an initial set position and is consistent with an initial sample suction state, at the moment, part of residual sample and recoil liquid are needed to be added to the sample inlet end of the blood separating valve, the whole channel is cleaned, cross pollution is reduced, the next sample separation is ready, the three-way channel is changed into five channels, automatic quantitative treatment is optimized, the automatic counting speed is increased, the medical time is shortened, the medical time is saved, and the medical time is saved.
Further, the five-channel micro quantitative blood separating valve 5 includes a WBC channel 51, a RBC channel 52, a WOC channel 53, a RET channel 54 and a NRBC channel 55, where the WBC channel 51, the RBC channel 52, the WOC channel 53, the RET channel 54 and the NRBC channel 55 are fixedly connected with the ceramic blood separating valve front cover 1, the ceramic splitter 2 and the ceramic blood separating valve rear cover 3, and penetrate through the ceramic blood separating valve front cover 1, the ceramic splitter 2 and the ceramic blood separating valve rear cover 3, and are arranged in a circular array.
In this embodiment, the five-channel micro quantitative blood separating valve 5 includes a WBC channel 51, a RBC channel 52, a WOC channel 53, a RET channel 54 and a NRBC channel 55, wherein the WBC channel 51, the RBC channel 52, the WOC channel 53, the RET channel 54 and the NRBC channel 55 are fixedly connected with the ceramic blood separating valve front cover 1, the ceramic splitter 2 and the ceramic blood separating valve rear cover 3, and penetrate through the ceramic blood separating valve front cover 1, the ceramic splitter 2 and the ceramic blood separating valve rear cover 3, are arranged in a circular array form, and on the basis of three conventional WBC channels 51, RBC channels 52 and WOC channels 53, the RET channel 54 and the NRBC channel 55 are added, as the two channels have larger diameters, and the error of the NRBC stored sample is required to be about +/-0.5 ul, so that bubbles are reduced for sample injection, the sample is fully stored, the sample channel 6 is cleaned without residues, a chamfer 10 is required to be formed on a corresponding hole site of a front cover and a rear cover of a blood separating valve, so that flowing liquid is sufficient and cleaned, wherein RET is reticulocyte, is an important evaluation index for clinical anemia treatment effect and treatment test, NRBC is nucleated red blood cell, and is one of important indexes for judging hyperplastic anemia, erythroleukemia, pernicious anemia and cancer tumor. The RBC channel 52, the WOC channel 53 and the NRBC channel 55 are curved steel pipes, the volumes of the three steel pipes are precisely and quantitatively calculated, the required HGB, NRBC and WOC sample quantification is stored, the three channels are changed into five channels, the micro quantification is optimized, the counting time is shortened for rapid automatic counting, and the time and the economic cost are saved for the used medical unit mechanism.
Further, the WBC channel 51, the RBC channel 52, the WOC channel 53, the RET channel 54 and the NRBC channel 55 are provided with inlets and outlets, the inlets of the WBC channel 51, the RBC channel 52 and the NRBC channel, the outlets 552 of the WBC channel 51, the RET channel 54 and the NRBC channel penetrate through the ceramic blood separation valve front cover 1, and the inlets 541 of the WOC channel 53 and the RET channel, the outlets 53 and 522 of the RBC channel penetrate through the ceramic blood separation valve rear cover 3.
In the present embodiment, the WBC channel 51, the RBC channel 52, the WOC channel 53, the RET channel 54, and the NRBC channel 55 each have an inlet and an outlet, and the WBC channel inlet 511, the RBC channel inlet 521, and the NRBC channel inlet 551, the WBC channel outlet 512, the RET channel outlet 542, and the NRBC channel outlet 552 each penetrate the ceramic blood separation valve front cover 1; the WOC channel inlet 531, the RET channel inlet 541, the WOC channel outlet 532 and the RBC channel outlet 522 all penetrate through the ceramic blood separating valve rear cover 3, and the structure is as shown in fig. 3 and 4, the whole blood separating valve is formed by communicating with the three curved steel pipes from the steel pipe inlet to the steel pipe outlet, and the whole blood separating valve is formed by communicating with the three curved steel pipes, the inner holes of the blood separating valve separating plates are also filled with samples at the moment, wherein the quantitative sizes of the samples of RBC and RET are determined by the volume of the inner holes of the separating plates, the arrangement of the hole positions is that the ceramic blood separating valve front cover 1 is arranged, the hole positions of the ceramic separating plates 2 and the ceramic blood separating valve rear cover 3 are not allowed to be crossed in the rotating process, because the sample pollution, dilution and inaccurate quantification are possibly caused in the process of crossing the hole positions, the hole positions between the sample channels 6 are not crossed in the rotating process, the sample positions are separated from each other, the sample is ensured to be consistent in the quantitative of the sample sucking samples, the sample sucking holes are ensured to be crossed in the NRBC and the rotating process, the hole positions are ensured to be crossed in the same space, the same, the space is not to be crossed, the distance is not is reduced, and the distance is easy, and the distance is reduced, the distance is not is easy, and the distance is easy to be reduced, and the distance is the edge is easy to be directly and the phenomenon is easy.
Further, the multichannel micro quantitative system of the blood cell analyzer further comprises a sample channel 6, wherein the sample channel 6 is fixedly connected with the front cover 1 of the ceramic blood separating valve and penetrates through the front cover 1 of the ceramic blood separating valve.
In this embodiment, the multichannel micro quantitative system of the blood cell analyzer further includes a sample channel 6, where the sample channel 6 is fixedly connected with the front cover 1 of the ceramic blood separating valve and penetrates through the front cover 1 of the ceramic blood separating valve, the structure of the sample channel is shown in fig. 3, the detection sample enters the blood separating valve from the inlet 61 of the sample channel, and after the detection is completed, as part of the residual sample and the mixed solution exist in the channel, the sample channel outlet 62 of the blood separating valve needs to recoil the reagent to the sample injection end of the blood separating valve, and the whole channel is cleaned.
Further, the multichannel micro quantitative system of the blood cell analyzer further comprises a sampling quantitative sensor 7, wherein the sampling quantitative sensor 7 is fixedly connected with the sample channel 6 and is positioned at one side far away from the front cover 1 of the ceramic blood separating valve.
In this embodiment, the multichannel micro quantitative system of the blood cell analyzer further includes a sampling quantitative sensor 7, where the sampling quantitative sensor 7 is fixedly connected with the sample channel 6 and is located at a side far away from the front cover 1 of the ceramic blood separating valve, and the sampling quantitative sensor 7 is used to monitor the sucked amount of the detection sample in real time and collect a curve through which blood flows, so as to analyze and obtain a state of full sucked blood, so that the subsequent analysis is convenient.
Further, the multichannel micro quantitative system of the blood cell analyzer further comprises a liquid path sensor 8, wherein the liquid path sensor 8 is fixedly connected with the sample channel 6 and is positioned at one side of the sample channel inlet 61 and the sample channel outlet 62.
In this embodiment, the multichannel micro quantitative system of the blood cell analyzer further includes a liquid path sensor 8, where the liquid path sensor 8 is fixedly connected to the sample channel 6 and located at one side of the sample channel inlet 61 and one side of the sample channel outlet 62, and the liquid path sensor 8 is used to detect whether the sample is completely filled in the blood separating valve cavity, so that the liquid path sensor 8 of the sample channel inlet 61 and the sample channel outlet 62 both require that the sample is detected at the same time, and at this time, all the steel pipes connected from the sample inlet to the sample outlet of the whole blood separating valve are filled with the sample.
Further, the multichannel micro quantitative system of the blood cell analyzer further comprises a limiting block 9, wherein the limiting block 9 is fixedly connected with the ceramic splitter plate 2, is rotationally connected with the ceramic blood separating valve front cover 1 and the ceramic blood separating valve rear cover 3, and is positioned on one side of the ceramic blood separating valve front cover 1, the ceramic splitter plate 2 and the ceramic blood separating valve rear cover 3.
In this embodiment, the multichannel micro quantitative system of the blood cell analyzer further includes a limiting block 9, the limiting block 9 is fixedly connected with the ceramic splitter plate 2, and is rotationally connected with the ceramic splitter plate front cover 1 and the ceramic splitter plate rear cover 3, and is located at one side of the ceramic splitter plate front cover 1, the ceramic splitter plate 2 and the ceramic splitter plate rear cover 3, when the sample enters the blood splitting valve cavity to split blood, the rotating valve plate mechanism 4 drives the ceramic splitter plate front cover 1 to rotate anticlockwise, the ceramic splitter plate rear cover 3 is selected clockwise, the middle ceramic splitter plate 2 is not moved, the ceramic splitter plate front cover 1 and the notch above the ceramic splitter plate rear cover 3 rotate to the position of the limiting block 9, as shown in fig. 2, the sample which is connected into a channel before is cut into five independent channels, when the sample enters the blood splitting valve cavity to split blood, the sample is switched back to an initial state, the rotating valve plate mechanism 4 drives the ceramic splitter plate front cover 1 to rotate anticlockwise, the ceramic splitter plate 2 rotates anticlockwise, and the ceramic splitter plate 3 rotates anticlockwise, and the ceramic splitter plate 2 is kept at the initial position, and the ceramic splitter plate is still kept unchanged, and the sample is kept at the anticlockwise.
Further, the ceramic blood separation valve front cover 1 and the ceramic blood separation valve rear cover 3 are provided with chamfer angles 10, and the chamfer angles 10 are positioned at the joint of the ceramic blood separation valve front cover 1 and the ceramic blood separation valve rear cover 3 and the ceramic flow dividing sheet 2.
In this way, in the process of sample suction and cleaning, the ceramic splitter 2 of the blood separating valve has a pore diameter larger than that of the through hole of the rear cover of the front cover due to quantitative requirement, which is equivalent to that of the sample from small caliber to large caliber and then from small caliber, thus having a problem that gaps are generated at four corners of the large caliber, vortex is easy to form, and filling and backflushing cleaning are not facilitated, so that reasonable chamfering 10 treatment is carried out at the through holes of the front cover 1 of the ceramic blood separating valve and the rear cover 3 of the ceramic blood separating valve, and the structure is shown in fig. 5. Considering the factor of rotation error, the outer circle of the front and rear cover chamfer 10 is slightly larger than the aperture of the through hole of the flow dividing piece, so the design is favorable for filling the aperture of the flow dividing block with the sample, reducing the formation of vortex, being favorable for cleaning the back flushing cleaner, and reducing the variation and complexity of the process.
The multichannel micro quantitative system of the blood cell analyzer comprises a ceramic blood separating valve front cover 1, a ceramic flow dividing sheet 2, a ceramic blood separating valve rear cover 3, a rotary valve sheet mechanism 4 and a five-channel micro quantitative blood separating valve 5, wherein the ceramic blood separating valve front cover 1 is rotationally connected with the ceramic flow dividing sheet 2 and is positioned on one side of the ceramic flow dividing sheet 2, the ceramic blood separating valve rear cover 3 is rotationally connected with the ceramic flow dividing sheet 2 and is positioned on one side far from the ceramic blood separating valve front cover 1, the rotary valve sheet mechanism 4 is fixedly connected with the ceramic blood separating valve front cover 1 and is positioned on one side far from the ceramic flow dividing sheet 2, the five-channel micro quantitative blood separating valve 5 is fixedly connected with the ceramic blood separating valve front cover 1, the ceramic flow dividing sheet 2 and the ceramic blood separating valve rear cover 3, and penetrates through the ceramic blood separating valve front cover 1, the ceramic flow dividing sheet 2 and the ceramic blood separating valve rear cover 3, the five-channel micro quantitative blood separating valve rear cover 5 comprises a plurality of channels, the channels are arranged in a circular shape, and the time for detecting and the micro-channel array is increased, and the micro-channel sample is used for detecting and the micro-volume array is washed.
The above disclosure is only a preferred embodiment of the present invention, and it should be understood that the scope of the invention is not limited thereto, and those skilled in the art will appreciate that all or part of the procedures described above can be performed according to the equivalent changes of the claims, and still fall within the scope of the present invention.
Claims (6)
1. The multichannel micro quantitative system of the blood cell analyzer is characterized by comprising a ceramic blood separating valve front cover, a ceramic flow dividing sheet, a ceramic blood separating valve rear cover, a rotary valve sheet mechanism and a five-channel micro quantitative blood separating valve, wherein the ceramic blood separating valve front cover is rotationally connected with the ceramic flow dividing sheet and is positioned on one side of the ceramic flow dividing sheet, the ceramic blood separating valve rear cover is rotationally connected with the ceramic flow dividing sheet and is positioned on one side far from the ceramic blood separating valve front cover, the rotary valve sheet mechanism is fixedly connected with the ceramic blood separating valve front cover and is positioned on one side far from the ceramic flow dividing sheet, and the five-channel micro quantitative blood separating valve is fixedly connected with the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover and penetrates through the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover;
The five-channel micro quantitative blood separating valve 5 consists of 5 channels, the blood separating valve consisting of the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover is used for carrying out accurate quantitative separation on a whole blood sample through relative selective movement, and the separated blood sample is separated into different independent reaction tanks;
the five-channel micro quantitative blood separating valve comprises a WBC channel, a RBC channel, a WOC channel, a RET channel and an NRBC channel, wherein the WBC channel, the RBC channel, the WOC channel, the RET channel and the NRBC channel are fixedly connected with the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover, penetrate through the ceramic blood separating valve front cover, the ceramic flow dividing sheet and the ceramic blood separating valve rear cover and are arranged in a circular array mode;
The WBC channel, the RBC channel, the WOC channel, the RET channel and the NRBC channel are provided with inlets and outlets, the inlets of the WBC channel, the RBC channel and the NRBC channel, the outlets of the WBC channel, the RET channel and the NRBC channel penetrate through the ceramic blood separating valve front cover, and the inlets of the WOC channel and the RET channel, the outlets of the WOC channel and the RBC channel penetrate through the ceramic blood separating valve rear cover.
2. A multi-channel micro-quantitative system for a blood cell analyzer according to claim 1, it is characterized in that the multichannel micro quantitative system of the blood cell analyzer also comprises a sample channel, the sample channel is fixedly connected with the ceramic blood separation valve front cover and penetrates through the ceramic blood separation valve front cover.
3. The multi-channel micro quantitative system of claim 2, further comprising a sample quantitative sensor fixedly connected to the sample channel and located at a side far from the front cover of the ceramic blood separation valve.
4. The multi-channel micro-scale quantification system of claim 2, further comprising a fluid path sensor fixedly connected to the sample channel and positioned on the side of the sample channel inlet and the sample channel outlet.
5. The multi-channel micro quantitative system of claim 1, further comprising a limiting block fixedly connected to the ceramic splitter plate, rotatably connected to the front cover of the ceramic splitter valve and the rear cover of the ceramic splitter valve, and positioned on one side of the front cover of the ceramic splitter valve, the ceramic splitter plate, and the rear cover of the ceramic splitter valve.
6. The multi-channel micro quantitative system of claim 1, wherein the front cover and the rear cover have chamfers, and the chamfers are positioned at the joints of the front cover and the rear cover and the ceramic splitter plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010186586.0A CN111175091B (en) | 2020-03-17 | 2020-03-17 | Multi-channel micro-quantification system for blood cell analyzer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010186586.0A CN111175091B (en) | 2020-03-17 | 2020-03-17 | Multi-channel micro-quantification system for blood cell analyzer |
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| Publication Number | Publication Date |
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| CN111175091A CN111175091A (en) | 2020-05-19 |
| CN111175091B true CN111175091B (en) | 2025-07-08 |
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