CN111643100B - Information Characterization Method and System for Phase Contrast Imaging System - Google Patents

Abstract

The invention discloses a method for characterizing phase contrast imaging information, comprising: acquiring original data of phase contrast imaging; extracting phase contrast information and dark field information according to the original data; and extracting the extracted phase contrast information and dark field information The information is characterized by the formula: H=D'·sin(P'), where H is the mixed field contrast of the phase contrast information and the dark field information, and P' is the corresponding data of the phase contrast information adjusted to [﹣π, The phase shift within π], D', the image contrast reduction ratio after performing the indexing operation on the corresponding data of the dark field information. By processing the extracted phase contrast information and dark field information, the original phase contrast information and dark field information can be represented in a mixed field image, which is different from the original phase contrast image and dark field image. In contrast, the image representation is clear, and it has a clearer physical meaning than ordinary image fusion methods.

Description

Information Characterization Method and System for Phase Contrast Imaging System

technical field

The invention relates to the field of radiation imaging, in particular to a method and system for characterizing phase contrast imaging information.

Background technique

Phase contrast imaging technology mainly uses X-rays to irradiate the object to be tested, which can achieve local structure resolution at the micron or even sub-micron level, which is a good complement to the traditional X-ray attenuation imaging technology. This technique can simultaneously characterize three kinds of contrast information of absorption, phase contrast and dark field, and is suitable for low atomic number, low density substances, especially for biological soft tissue structures including breast. At present, X-ray phase contrast imaging technology mainly characterizes three kinds of contrast information, including absorption information, phase contrast information and dark field information. These three kinds of contrast information can respectively characterize the attenuation, phase shift and small-angle scattering of X-rays in the object. These kinds of characterization quantities have clear physical meanings. For example, the attenuation corresponds to the linearity of the object. The attenuation coefficient and the phase offset correspond to the real part of the complex refractive index of the object, and the small-angle scattering amount corresponds to the generalized scattering parameter of the object.

In practical applications (such as medical imaging applications), it is of great practical value for users viewing images (such as radiophysicists) to be able to present all the most relevant information as condensed as possible. Therefore, for X-ray phase contrast imaging technology, this is an important research direction, that is, to select an appropriate characterization quantity to integrate the above three contrast information as much as possible, especially the integration of phase contrast imaging Unique phase contrast information and dark field information. In the existing technology and research, the traditional technical means is to feed back three kinds of information of absorption, phase contrast and dark field to the user in two ways. The first is to pass the three kinds of information through three different absorption images and phase contrast images. , Dark field images are more accurate for users, but users need to view three images at the same time, which is very inconvenient; the second is to obtain three different images in one way, and one image is obtained after image processing operation on two of the images. , which can reflect three kinds of information to the user at the same time, that is, image fusion through post-processing of several contrast information images represented. Although the images obtained by these fusion methods can also reflect a variety of information, they are obtained through image processing. , there is no clear physical meaning, and some defects in the image processing algorithm cannot explain the connection between the obtained single image and the three contrast images represented by the original information, that is, it will cause the three contrast images of the single image finally obtained. Such information cannot clearly correspond to actual substance information.

In order to solve the above problems, the present invention proposes a phase contrast imaging information representation method and system, which can realize the direct representation of the original phase contrast information and dark field information in an image, and has a clear physical definition.

SUMMARY OF THE INVENTION

(1) Technical problems to be solved

In order to enable users to use the same image to view two kinds of information of phase contrast and dark field at the same time, and at the same time to ensure that the image information is clear and accurate, the present invention proposes a method and system for characterizing phase contrast imaging information, and a readable storage medium, as follows:

(2) Technical solutions

One aspect of the present invention provides a method for characterizing phase contrast imaging information, the method includes: acquiring original data of phase contrast imaging; extracting phase contrast information and dark field information according to the original data; extracting phase contrast information and dark field information Information is characterized by the following formula:

H=D′·sin(P′)

Among them, H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the corresponding data of the dark field information The ratio of image contrast reduction after exponential operation.

Optionally, extracting the phase contrast information and the dark field information according to the original data is realized by including the FCA algorithm, the SAXS algorithm or the AAXS algorithm.

Optionally, after extracting the phase contrast information and the dark field information according to the original data, the method further includes: performing a normalization operation on the corresponding data of the phase contrast information to obtain a phase offset P' adjusted to [-π, π] ; The image contrast reduction ratio D' obtained by performing the indexing operation on the corresponding data of the dark field information.

Another aspect of the present invention provides a phase contrast imaging information characterization system, applying the above method, the system includes: an optical imaging device for acquiring original data of phase contrast imaging; an information extraction device for obtaining according to the optical imaging device Extract the phase contrast information and dark field information from the original data of

H=D′·sin(P′)

Characterization, where H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the contrast of the dark field information The ratio of image contrast reduction after indexing the corresponding data.

Optionally, the optical imaging device is an analytical imaging device, an edge illumination imaging device, a spot imaging device or a grating imaging device.

Optionally, the grating imaging device is a Talbot-Lau type, a geometric projection type or a dual phase grating type.

Optionally, the position to be measured for illumination of the grating imaging device is located between the light source and the first grating or between the first grating and the second grating.

Optionally, the light source of the optical imaging device is a conventional X-ray light source, a microfocus X-ray light source or a synchrotron radiation X-ray light source, and the detector of the optical imaging device is an energy integration detector or a photon counting detector.

Another aspect of the present invention provides a system for characterizing phase contrast imaging information. The system includes: a processor; Methods.

Another aspect of the present invention provides a computer-readable storage medium. The computer-readable storage medium stores a data processing program. When the data processing program is executed by a processor, the above method is implemented.

(3) Beneficial effects

The method and system for characterizing phase contrast imaging information proposed by the present invention can characterize the original phase contrast information and dark field information in a mixed field image by processing the extracted phase contrast information and dark field information. Compared with the original phase-contrast image and dark-field image, the mixed-field image has a clear image representation, and has a clearer physical meaning than the common image fusion method.

Description of drawings

1 is a schematic flowchart of a method for characterizing phase contrast imaging information in an embodiment of the present invention;

2 is an imaging comparison diagram of three kinds of information of absorption, phase contrast, and dark field respectively extracted by three algorithms of FCA, SAXS, and AAXS in the embodiment of the present invention;

FIG. 3 is an imaging comparison diagram of the dark field information extracted by the hybrid characterization of the AAXS algorithm and the FCA and SAXS algorithms, respectively, in an embodiment of the present invention.

Detailed ways

In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below with reference to specific embodiments and accompanying drawings.

In order to enable users to use the same image to view two kinds of information of phase contrast and dark field at the same time, and at the same time to ensure that the image information is clear and accurate, the present invention proposes a method and system for characterizing phase contrast imaging information, and a readable storage medium, as follows:

One aspect of the present invention proposes a method for characterizing phase contrast imaging information. FIG. 1 is a schematic flowchart of the method for characterizing phase contrast imaging information in an embodiment of the present invention. The method includes:

S110, acquiring raw data of phase contrast imaging;

S120, extracting phase contrast information and dark field information according to the original data;

S130, characterize the extracted phase contrast information and dark field information by the following formula:

H=D′·sin(P′)

Among them, H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the corresponding data of the dark field information The ratio of image contrast reduction after exponential operation.

Specifically, in the embodiment of the present invention, an X-ray phase contrast grating imaging device is used as the phase contrast imaging system, and the X-ray phase contrast grating imaging device includes an X-ray light source, a source grating, a phase grating, an analysis grating source grating and a detector, Specifically, the phase grating spacing can be 1020mm, the source grating to analysis grating spacing is 1280mm, the source grating, phase grating and analysis grating periods are 16.8μm, 4.2μm and 2.4μm respectively, and the X-ray tube parameters are 35kVp and 35mA, The detector pixel is 74.8 μm × 74.8 μm, and the number of phase steps is 8.

After the above-mentioned X-ray phase contrast imaging system collects the original data, it is necessary to use the information extraction algorithm to extract three kinds of information: absorption information, phase-contrast information, and dark-field information. Extraction, hereinafter represented by A, P, and D, respectively. The present invention will be described in detail by taking the characterization of phase contrast information and dark field information as an embodiment. Phase contrast information can be understood as the X-ray phase shift caused by the refraction of X-rays through the object after the object is irradiated by X-rays; dark field information can be understood as the X-rays scattered by the object after the object is irradiated by X-rays. X-ray image contrast changes. The present invention defines a new X-ray phase contrast imaging physical characterization quantity H, which is used to characterize the dark field information and the phase contrast information in the same mixed field, and the mixed field information can be displayed to the user in the form of a single image. Among them, the X-ray phase contrast imaging physical characterization quantity, that is, the "Hybrid-field" contrast H, satisfies the following formula (1):

H=D′·sin(P′)

Among them, H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the corresponding data of the dark field information The ratio of image contrast reduction after exponential operation.

Optionally, extracting the phase contrast information and the dark field information according to the original data is realized by including the FCA algorithm, the SAXS algorithm or the AAXS algorithm.

Specifically, in the embodiment of the present invention, in the grating-based X-ray phase contrast imaging system, the phase contrast information and the dark field information are extracted according to the original data. In the present invention, there are at least FCA (Fourier Component Analysis) algorithm, SAXS algorithm There are three extraction algorithms (Small Angle X-ray Scattering) algorithm or AAXS algorithm. Through these three extraction algorithms, the phase contrast information and dark field information corresponding to the original data can be obtained. The three extraction algorithms are described in detail below:

In the FCA algorithm, both the background displacement curve f(φ) and the object displacement curve s(φ) collected by the grating-based X-ray phase contrast imaging system are assumed to be cosine models, namely formulas (2) and (3):

和

分别为背景位移取线和物体位移曲线的零阶、一阶Fourier成分幅度，

为两者的一阶Fourier成分幅角。in,

and

are the zero-order and first-order Fourier component amplitudes of the background displacement line and the object displacement curve, respectively,

is the first-order Fourier component argument of both.

The FCA algorithm can calculate the parameters of the background displacement curve f(φ) and the object displacement curve s(φ) through the fast Fourier transform, and then obtain the extracted absorption information A _FCA , phase contrast information P _FCA and dark field information D _FCA , Specifically, it can be expressed in the following forms, namely formulas (4), (5) and (6):

为两位移曲线的相位差，

分别为物体位移曲线和背景位移曲线的对比度。Among them, A, P, and D represent absorption information, phase contrast information, and dark field information, respectively, p ₂ is the period of the last grating near the detector in grating phase contrast imaging, and d is the distance between the last two gratings.

is the phase difference between the two displacement curves,

are the contrast of the object displacement curve and the background displacement curve, respectively.

Therefore, it can be seen that the FCA algorithm is based on the cosine model assumption, and can extract three kinds of information through fast Fourier transform, which is convenient and efficient, but there is an inherent phase-wrapping problem (Phase-wrapping), which may affect the image quality in practical applications. Larger impact, it is easy to cause poor image quality.

In the SAXS algorithm, the background displacement curve and the object displacement curve collected by the grating-based X-ray phase contrast imaging system are collected. Among them, the basic assumption is that the object displacement curve s(φ) can be expressed as the convolution of the background displacement curve f(φ) and the small-angle scattering distribution g(φ), and its expression is as follows, namely formula (7):

Based on the above formula (7), the small-angle scattering distribution is obtained by deconvolution from the background displacement curve f(φ) and the object displacement curve s(φ) on each detector pixel collected by the Lucy-Richardson iteration method. , the k-th iteration calculation formula in the deconvolution process is formula (8):

表示f关于原点的镜像对称，通常选择g⁰＝s作为初始值。然后可以将传统FCA方法提取出的吸收(A)、相衬(P)和暗场(D)三种对比度信息表示为小角散射分布的零阶矩M₀(g)、一阶矩M₁(g)和二阶矩M₂(g)，即公式(9)、(10)和(11)：in,

Indicates the mirror symmetry of f about the origin, and g ⁰ =s is usually chosen as the initial value. Then the three contrast information of absorption (A), phase contrast (P) and dark field (D) extracted by the traditional FCA method can be expressed as the zero-order moment M ₀ (g) and the first-order moment M ₁ ( g) and the second moment M ₂ (g), namely formulas (9), (10) and (11):

A→M ₀ (g)=∫g(φ)dφ

P→M ₁ (g)=∫φg(φ)dφ/M ₀ (g)

D→M ₂ (g)=∫(φ-M ₁ (g)) ² g(φ)dφ/M ₀ (g))

Therefore, it can be seen that the SAXS algorithm is based on the convolution assumption, obtains the small-angle scattering distribution by deconvolution, and then calculates its multi-order moment to obtain three kinds of information, avoiding the phase warping problem of FCA, but due to the need for deconvolution Iteration, the operation efficiency is low, and the iterative method and stopping conditions need to be set in advance, and these differences will have a greater impact on the iterative results.

Like the SAXS method, the AAXS information extraction algorithm does not depend on the assumption of the cosine model. It can be directly based on the background displacement curve f(φ) and object displacement curve s(φ) of the original data collected by the grating X-ray phase contrast imaging system. Absorption (M ₀ ), phase contrast (M ₁ ) and dark field (M ₂ ) three kinds of information are extracted, which can be expressed as three kinds of multi-order moments, namely formulas (12), (13) and (14):

Among them, SinM ₁ (·) and CosM ₁ (·) are defined as follows, namely formulas (15) and (16):

SinM ₁ (y)=∫sin(φ)y(φ)dφ,

CosM ₁ (y)=∫cos(φ)y(φ)dφ.

Therefore, it can be seen that the ASAXS algorithm avoids the phase winding problem of the FCA algorithm and the deconvolution iteration problem of the SAX algorithm, and the operation efficiency is higher.

It should be noted that the above three information extraction algorithms can all be in the form of formula (1). By processing the phase contrast information and the dark field information, the corresponding P' and D' can be obtained, and then the phase contrast information and dark field information can be obtained. The mixed field information H of the field information is the mixed field contrast of the phase contrast information and the dark field information, so that the dark field information and the phase contrast information can be represented in the same mixed field, and the mixed field information can be displayed to the user in the form of a single image. show.

Optionally, extracting the phase contrast information and the dark field information according to the original data includes: acquiring absorption information according to the original data; and extracting the phase contrast information and the dark field information from the original data and/or the absorption information. In the embodiment of the present invention, as shown in formulas (12), (13) and (14), the absorption information M ₀ is obtained according to the original data, and the phase contrast information M ₁ is obtained according to the original data and the absorption information M ₀ . The field information M ₂ is obtained according to the original data, absorption information M ₀ , and phase contrast information M ₁ .

Optionally, after extracting the phase contrast information and the dark field information according to the original data, the method further includes: performing a normalization operation on the corresponding data of the phase contrast information to obtain a phase offset P' adjusted to [-π, π] ; The image contrast reduction ratio D' obtained by performing the indexing operation on the corresponding data of the dark field information.

In the embodiment of the present invention, taking the AAXS algorithm as an example, the cosine model in the formula (2) (3) is substituted into the formula (12) (13) (14) to establish the connection between the FCA algorithm and the AAXS algorithm, that is, The absorption (M ₀ ), phase contrast (M ₁ ) and dark field (M ₂ ) information extracted by the ASAXS algorithm can be re-expressed as absorption information (A _ASAXS ), phase contrast information (P _ASAXS ) and dark field information (D _ASAXS ), i.e. equations (17), (18) and (19):

The first-order moment information obtained by formula (18) is essentially a mixed form of phase contrast information and dark field information extracted by the original FCA algorithm. This mixed field information physically combines phase contrast information and dark field information. Field information, and in some cases can be simply processed to highlight one of them. For example, when imaging a uniform object with light materials, the phase offset φ _c is often close to 0, so the logarithm of formula (18) can be taken at this time, and the dark field information similar to formula (6) can be obtained, That is, the dark field information D', that is, formula (20):

Among them, the first item is the dark field information in (6), the second item is a small quantity, and the third item is a constant quantity.

In addition, when imaging an object with less scattering, the degree of contrast reduction is not obvious, then formula (18) can be approximated as the phase contrast information in formula (5), correspondingly, the phase contrast information P' can be obtained. Therefore, the mixed field contrast H in the formula (1) can be defined according to the information. Based on the above expression, whether it is based on the direct extraction method of the original data such as the AAXS algorithm, or the indirect extraction method of the original data according to, for example, the FCA algorithm, the mixed field contrast H provided by the present invention can be used to compare the phase contrast information and the dark field. Therefore, the hybrid field contrast H proposed by the present invention has certain universality.

In the embodiment of the present invention, in the grating phase contrast imaging system, the experimental sample is a living mouse, the distance from the source grating to the phase grating is 1020 mm, the distance from the source grating to the analysis grating is 1280 mm, and the periods of the source grating, the phase grating and the analysis grating are respectively 16.8μm, 4.2μm and 2.4μm, the X-ray tube parameters are 35kVp and 35mA, the detector pixel is 74.8μm×74.8μm, and the number of phase steps is 8. In the embodiment of the present invention, as shown in FIG. 2, the imaging comparison diagram of the absorption, phase contrast, and dark field information corresponding to the extraction of the three algorithms of FCA, SAXS, and AAXS, and FIG. 3, the hybrid characterization of the AAXS algorithm in the embodiment of the present invention As shown in the imaging comparison diagram of the dark field information extracted by the FCA and SAXS algorithms respectively, it can be seen from Figure 2 that the mixed field image proposed by the present invention (that is, the phase contrast image of AAXS) is very similar to the original phase contrast image in most areas. It can be seen from Figure 3 that after the simple operation of taking the logarithm of the absolute value of formula (15), the mixed field image proposed by the present invention is very similar to the dark field information in Figure 1. The above results show that the proposed mixed field Physical characterization quantities can better reflect the characteristics of phase contrast and dark field information.

The above is an embodiment of grating-based X-ray phase contrast imaging. For other X-ray phase contrast imaging embodiments, the physical characterization quantity of the mixed field proposed by the present invention can be calculated according to formula (1), that is, the first The phase contrast information and dark field information are calculated by the traditional method, and then the mixed field information is obtained by calculating according to formula (1).

Another aspect of the present invention provides a phase contrast imaging information characterization system, applying the above method, the system includes: an optical imaging device for acquiring original data of phase contrast imaging; an information extraction device for obtaining according to the optical imaging device Extract the phase contrast information and dark field information from the original data of

H=D′·sin(P′)

Characterization, where H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the contrast of the dark field information The ratio of image contrast reduction after indexing the corresponding data.

Optionally, the optical imaging device is an analytical imaging device, an edge illumination imaging device, a spot imaging device or a grating imaging device. The optical imaging device is used as the acquisition device of raw data, which is not limited to the analysis imaging device based on analysis crystal (Analyzer-based Imaging, ABI), the edge illumination imaging device based on edge illumination (Edge-Illumination, EI), the spot imaging based on speckle Various phase contrast imaging systems such as Specckle-based Imaging and Grating-based Imaging (GI) can be used to obtain the original data of absorption information, phase contrast information and dark field information.

Optionally, the grating imaging device is a Talbot-Lau type, a geometric projection type or a dual phase grating type. The types of grating imaging devices are not limited, that is, grating imaging devices of various types of systems such as Talbot-Lau type, geometric projection type, and dual-phase grating type can be included. In order to obtain the original data of three kinds of information: absorption information, phase contrast information and dark field information.

Optionally, the position to be measured for illumination of the grating imaging device is located between the light source and the first grating or between the first grating and the second grating. In addition, the position of the object can be placed between the light source and the first grating, or between the two gratings. The grating imaging device is generally a light source, a first grating, and a detector, or a light source, a first grating, a second grating, and a detector. Therefore, the position of the object to be measured can be located between the light source and the first grating, or it can be between the first grating and the second grating. The change of the position to be measured is related to the acquisition of imaging information and the accuracy of the imaging information.

Optionally, the light source of the optical imaging device is a conventional X-ray light source, a microfocus X-ray light source or a synchrotron radiation X-ray light source, and the detector of the optical imaging device is an energy integration detector or a photon counting detector. In addition, the X-ray source can be either a conventional X-ray source, a microfocus X-ray source or a synchrotron radiation X-ray source. In addition, the detector can be either an energy-integrating detector or a photon-counting detector.

The method and system for characterizing phase contrast imaging information proposed by the present invention can characterize the original phase contrast information and dark field information in a mixed field image by processing the extracted phase contrast information and dark field information. Compared with the original phase-contrast image and dark-field image, the mixed-field image has a clear image representation, and has a clearer physical meaning than the common image fusion method.

Another aspect of the present invention provides a system for characterizing phase contrast imaging information, the system comprising: a processor; a memory on which a computer program executable on the processor is stored, wherein the computer program is executed by the processor At the same time, the method steps described in the above embodiments are implemented. The apparatus for extracting information of a raster imaging system in the embodiment of the present invention includes a processor (eg, a microprocessor (μP), a digital signal processor (DSP), etc.). The processor may be a single processing unit or multiple processing units for executing different actions of the method flow described in the embodiments of the present invention. In addition, the apparatus may include at least one computer-readable storage medium in the form of non-volatile or volatile memory, as described in detail below.

Another aspect of the present invention provides a computer-readable storage medium, where a data processing program is stored thereon, and when the data processing program is executed by a processor, the methods described in the above embodiments are implemented. The information extraction methods of embodiments of the present invention may take the form of a computer program product on a computer-readable storage medium storing instructions, the computer program product being usable by an instruction execution system (eg, one or more processors) or in combination with instructions Execute system usage. In the context of embodiments of the present invention, a computer-readable storage medium can be any medium that can contain, store, communicate, propagate, or transmit instructions. For example, a computer-readable storage medium may include, but is not limited to, an electrical, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, device, or propagation medium. Specific examples of computer-readable storage media include: magnetic storage devices, such as magnetic tapes or hard disks (HDDs); optical storage devices, such as compact disks (CD-ROMs); memories, such as random access memory (RAM) or flash memory; and/or wired/wireless communication link.

The specific embodiments described above further describe the purpose, technical solutions and beneficial effects of the present invention in further detail. It should be understood that the above descriptions are only specific embodiments of the present invention, and are not intended to limit the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims (10)

1. A method for characterizing phase contrast imaging information, wherein the method comprises: Obtain the raw data of phase contrast imaging; extracting phase contrast information and dark field information according to the original data; The extracted phase contrast information and dark field information are characterized by the following formula: H=D′·sin(P′) Among them, H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the phase shift of the dark field The ratio of the image contrast reduction after the indexing operation of the corresponding data of the information. 2 . The method according to claim 1 , wherein the extraction of phase contrast information and dark field information according to the original data is realized by including FCA algorithm, SAXS algorithm or AAXS algorithm. 3 . 3. The method according to claim 1, wherein after the phase contrast information and the dark field information are extracted according to the original data, the method further comprises: Perform a normalization operation on the corresponding data of the phase contrast information to obtain a phase offset P' adjusted to [-π, π]; The image contrast reduction ratio D' obtained by performing the indexing operation on the corresponding data of the dark field information. 4. A phase contrast imaging information characterization system, applying the method according to any one of claims 1-3, wherein the system comprises: An optical imaging device for acquiring raw data of phase contrast imaging; an information extraction device, configured to extract phase contrast information and dark field information according to the original data obtained by the optical imaging device; An information characterization device, configured to pass the formula according to the phase contrast information and the dark field information extracted by the information extraction device: H=D′·sin(P′) to characterize, where H is the mixed field contrast of the phase contrast information and dark field information, P' is the phase offset adjusted to [-π, π] for the corresponding data of the phase contrast information, D' is the phase shift for the phase contrast information The ratio of image contrast reduction after the indexing operation of the corresponding data of the dark field information. 5. The system according to claim 4, wherein the optical imaging device is an analytical imaging device, an edge illumination imaging device, a spot imaging device or a grating imaging device. 6. The system according to claim 5, wherein the grating imaging device is a Talbot-Lau type, a geometric projection type or a dual-phase grating type. 7 . The system according to claim 5 , wherein the position to be measured for illumination of the grating imaging device is located between the light source and the first grating or between the first grating and the second grating. 8 . 8. The system according to claim 4, wherein the light source of the optical imaging device is a conventional X-ray light source, a microfocus X-ray light source or a synchrotron radiation X-ray light source, and the detector of the optical imaging device is an energy source Integrating detectors or photon counting detectors. 9. A phase contrast imaging information characterization system, wherein the system comprises: processor; A memory having stored thereon a computer program executable on the processor, wherein the computer program, when executed by the processor, implements the method of any one of claims 1-3. 10. A computer-readable storage medium, characterized in that, a data processing program is stored on the computer-readable storage medium, and when the data processing program is processed and executed, the data processing program of any one of claims 1-3 is realized. Methods.

Images