CN111744110B - Pulse generator and implanted nerve stimulation system with wiring groove arranged on one side - Google Patents

Abstract

The present invention provides a pulse generator and an implantable neural stimulation system with a wiring slot arranged on one side, wherein the pulse generator comprises: a top cover component, including a top cover body, and an electrode connection device installed inside the top cover body; a main body component, including a shell, a circuit board installed inside the shell, and a feed-through wire electrically connected to the circuit board; the feed-through wire is used to be inserted into the top cover component and electrically connected to the electrode connection device; at least two electrode connection devices are provided inside the top cover body, and are arranged in parallel in a direction away from the main body component. The pulse generator of the present invention is thinner and lighter, the depth of the bone slot opened on the skull is shallower, the patient suffers less pain, and the operation is safer.

Description

A pulse generator and implantable neural stimulation system arranged on one side of a wiring slot

Technical Field

The present invention relates to the technical field of implantable medical instruments, and in particular to a pulse generator and an implantable neural stimulation system which are arranged on one side of a wiring slot and can be implanted in a head.

Background Art

Deep brain stimulation therapy is a reversible neuromodulation therapy that effectively treats related diseases by stimulating different functional nuclei deep in the brain with electrical pulses. At present, deep brain stimulation therapy can be used to treat Parkinson's disease, epilepsy, spasticity, essential tremor and other diseases. It is also being widely used in the treatment of Alzheimer's syndrome, refractory depression, post-stroke rehabilitation, pain and other aspects.

The implantable part of a traditional deep brain stimulation system generally includes a pulse generator, an extension lead, electrodes, and an electrode fixing device. The pulse generator is implanted under the chest skin and connected to the extension lead, which is connected to the electrode through a subcutaneous tunnel in the neck. The electrode passes through the skull to contact the target point and is fixed to the skull by a fixing device. However, during the implantation and use process, neck movement can easily lead to connection failure, and the skin at the connection site can easily break down, which brings great trouble to patients.

Chinese patent document CN109364372A discloses a top cover component, a pulse generator and an implantable electrical stimulation system, wherein the top cover component disclosed therein is provided with two electrode connection devices for inserting and connecting electrode wires, and the two electrode connection devices are arranged in a superimposed manner in the top cover component. If the pulse generator is implanted in the head, in the same position from the inside to the outside, there are the human body, the electrode connection device, the electrode connection device, and the scalp. Since the two electrode connection devices are arranged in a superimposed manner, the thickness of the device is large, and therefore a deeper bone groove needs to be opened on the skull, and the operation is more risky. Therefore, in order for the pulse generator to meet the new needs of the current deep brain electrical stimulation surgery, it is urgent to miniaturize the pulse generator and reasonably arrange the internal components.

Summary of the invention

Therefore, the technical problem to be solved by the present invention is to overcome the technical defects in the prior art that the pulse generator of the implantable electrical stimulation system is large in size and requires a deep bone groove to be opened when implanted in the head, which leads to a higher risk of surgery, thereby providing a pulse generator with thinner thickness, shallow bone groove and thus higher surgical safety.

The present invention also provides a neural stimulation system having the pulse generator.

To this end, the present invention provides a pulse generator arranged on one side of a wiring slot, comprising:

A top cover component, comprising a top cover body, and an electrode connecting device installed inside the top cover body;

The main body component includes a shell, a circuit board installed inside the shell, and a feedthrough wire electrically connected to the circuit board; the feedthrough wire is used to be inserted into the top cover component and electrically connected to the electrode connection device;

At least two electrode connection devices are provided inside the top cover body and are arranged in parallel in a direction away from the main body component.

The electrode connection device comprises a plurality of connectors, an insulating ring is provided between two adjacent connectors, and each connector is provided with a wiring slot;

All the wiring slots of the electrode connection devices are arranged toward the same side of the top cover component.

As a preferred solution, the feed-through wires extend from a recessed position on one side of the shell, and are then inserted into the interior of the top cover component to be electrically connected to corresponding wiring slots respectively.

As a preferred embodiment, a plurality of first limiting grooves are provided on the top cover component, and the first limiting grooves are directly opposite to the wiring groove of the electrode connecting device closest to the main body component. A portion of the feed-through wires pass through the first limiting grooves and directly extend into the wiring groove of the electrode connecting device closest to the main body component to be connected to the connector.

The top cover component is also provided with a plurality of second limiting grooves, which are not directly opposite to the connector of the electrode connecting device closest to the main body component. After another part of the feed-through wire passes through the second limiting groove, it goes around the insulating ring and enters between two adjacent electrode connecting devices, and then enters the wiring groove of other electrode connecting devices that are not closest to the main body component to be connected to the connector.

As a preferred embodiment, the electrode connecting device has a first positioning and mounting portion and a second positioning and mounting portion, and a mounting position for positioning and mounting the first positioning and mounting portion and the second positioning and mounting portion is provided inside the top cover body; the connector and the insulating ring are arranged between the first positioning and mounting portion and the second positioning and mounting portion.

As a preferred solution, the second positioning and mounting portion is provided with a first fixing hole connected to the insertion hole of the electrode connecting device for inserting and mounting the electrode wire;

A second fixing hole is provided on the top cover body opposite to the first fixing hole;

An elastic cap is installed at the position of the second fixing hole, and a normally closed opening is provided on the elastic cap;

A fixing bolt is passed through the second fixing hole and then screwed into the first fixing hole, so as to tighten the electrode wire inserted into the insertion hole.

As a preferred embodiment, a accommodating groove for accommodating and installing a charging coil is provided on one side surface of the top cover body away from the wiring groove of the electrode connecting device; an opening groove for allowing the charging coil to pass through and connect to the main body is provided on the side of the accommodating groove facing the main body.

As a preferred solution, the charging coil position is covered with silicone rubber.

As a preferred solution, it also includes an antenna, which is arranged in the installation gap formed between one end of the top cover body away from the main body component and the electrode connecting device.

As a preferred solution, a groove is provided on the outer wall of one end of the top cover body away from the main body component, and a fixed pressing plate is provided inside the groove.

The present invention also provides an implantable neural stimulation system, comprising:

Pulse generator;

An electrode wire, one end of which has a connection contact for connecting to the pulse generator, and the other end of which has a stimulation contact suitable for connecting to a nerve;

A fixing device, used for fixing the electrode wire to the skull;

an external control device capable of wirelessly communicating with the pulse generator;

The pulse generator is any one of the pulse generators described above.

The technical solution provided by the present invention has the following advantages:

1. The pulse generator of the present invention comprises a top cover component and a main body component, wherein the top cover component comprises a top cover body and an electrode connection device installed inside the top cover body; the main body component comprises a shell, a circuit board installed inside the shell, and a feedthrough wire electrically connected to the circuit board; the feedthrough wire is used to be inserted into the top cover component and electrically connected to the electrode connection device; at least two electrode connection devices are provided inside the top cover body and are arranged in parallel in a direction away from the main body component; the pulse generator of the present invention adjusts the arrangement of the electrode connection device inside the top cover component, reduces the thickness of the top cover component, and further reduces the thickness of the entire pulse generator. Compared with the prior art, the pulse generator of the present invention is thinner and lighter, the depth of the bone groove opened on the skull is shallower, the patient suffers less pain, and the operation is safer.

2. In the pulse generator of the present invention, all connectors on the electrode connecting devices are provided with wiring slots, and the wiring slots of all the electrode connecting devices are facing the same side of the top cover component, specifically the side of the top cover component facing the human body, so that the feed-through wires are conveniently extended from one side of the main body component to the inside of the top cover component, enter the wiring slots and are electrically connected to the connectors, thereby reducing connection interference between the top cover components, being able to reduce the thickness of the top cover component, and facilitating the assembly of the top cover component.

3. In the pulse generator of the present invention, the feed-through wire extends from a recessed position on one side of the shell, is inserted into the interior of the top cover component, and is electrically connected to the corresponding wiring slot. The feed-through wire extends from the above position, and then branches out and is inserted into the interior of the top cover component from different positions, and is electrically connected to the corresponding wiring slot. This method of the feed-through wire coming out from one side and then extending from different positions to the top cover component not only avoids the problem of complicated wiring and connection caused by the wire coming out from the side of the main part facing the top cover component, but also facilitates the lightweight manufacturing of the main part.

4. The pulse generator of the present invention has an electrode connection device that is closest to the main body component, and its connector is installed at a position that makes the wiring slot face the first limiting slot provided on the top cover component. In this way, after the feed-through wire extends out from the main body component, it directly enters the interior of this part of the wiring slot through the first limiting slot to achieve electrical connection. The line is short and almost does not occupy the internal space of the top cover component.

5. The pulse generator of the present invention is provided with a second limiting groove on the top cover part for other electrode connection devices that are not closest to the main part. The second limiting groove is not directly opposite to the connector of the electrode connection device that is closest to the main part. After the other part of the feed-through wire passes through the second limiting groove, it goes around the insulating ring and enters between two adjacent electrode connection devices, and then enters the wiring slot of other electrode connection devices that are not closest to the main part. In this arrangement, after the other part of the feed-through wire passes through the second limiting groove, it is basically directly opposite to the position of the insulating ring (it can also be other positions close to the connector), avoiding electrical connection with the connector of the electrode connection device closest to the main part; after going around the insulating ring, it enters between two adjacent electrode connection devices. When the electrode connection device is fixed, this part of the feed-through wire is compacted between the insulating ring and the inner wall of the top cover body. This wiring method makes full use of the gap space inside the top cover part, and the line wiring is regular and firmly fixed.

6. In the pulse generator of the present invention, the electrode connecting device is provided with a first positioning mounting portion and a second positioning mounting portion, and the top cover body is provided with mounting positions for positioning and mounting the first positioning mounting portion and the second positioning mounting portion. In this way, by positioning and mounting the first positioning mounting portion and the second positioning mounting portion inside the top cover body, the entire electrode connecting device can be positioned and mounted, and the remaining space can provide a wiring path for the feed-through wire.

7. The pulse generator of the present invention has a first fixing hole on the second positioning and mounting part that is connected to the jack of the electrode connection device for inserting the electrode wire, a second fixing hole is provided on the top cover body opposite to the first fixing hole, an elastic cap is installed at the position of the second fixing hole, and the elastic cap has a normally closed opening; it also includes a fixing bolt that passes through the second fixing hole and is screwed to the first fixing hole. When in use, a tool is used to pass through the normally closed opening of the elastic cap, cooperate with the fixing bolt, and turn the fixing bolt to rotate, expand and contract relative to the first fixing hole, thereby tightening or releasing the electrode wire inserted into the jack.

8. The pulse generator of the present invention has a groove for accommodating a charging coil on one side of the top cover body away from the wiring groove of the electrode connecting device. The charging coil is installed at this position. After the pulse generator is implanted in the human body, this position faces outward, which is convenient for charging with an external charger. The open groove provides a line path for connecting the power supply coil with the main body.

9. The pulse generator of the present invention uses silicone rubber to cover the charging coil, which can not only fix the charging coil, but also does not generate interference such as eddy current during charging, which is beneficial to improving the charging efficiency.

10. In the pulse generator of the present invention, an installation gap is formed between the end of the top cover body away from the main body component and the electrode connecting device, and the antenna is installed inside the installation gap. This assembly method fully utilizes the installation space of the top cover body and is conducive to the signal interaction between the antenna and the outside world.

11. The pulse generator of the present invention has a groove on the outer wall of one end of the top cover body away from the main body component, and a fixed pressure plate is provided inside the groove. When the pulse generator is implanted in the human body, the position of the fixed pressure plate can be pressed by a pressure piece fixed on the skull to fix this end of the pulse generator.

12. The present invention provides an implantable neural stimulation system, including a pulse generator, an electrode wire, a fixing device and an external control device, wherein the pulse generator is a pulse generator of the above structure. The implantable neural stimulation system of the present invention, because it adopts the above pulse generator, has all the advantages brought by the above pulse generator, such as good lightness and thinness, high charging efficiency, etc.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to more clearly illustrate the technical solutions in the prior art or the specific implementation manner of the present invention, the drawings used in the description of the prior art or the specific implementation manner are briefly introduced below.

FIG1 is a schematic diagram of the overall structure of a pulse generator of the present invention.

FIG. 2 is a schematic structural diagram of the top cover component and the main body component in FIG. 1 after being separated up and down.

FIG. 3 is a rear view of the main body component in FIG. 2 .

FIG. 4 is a schematic diagram of the exploded structure of the top cover component in FIG. 2 .

FIG. 5 is a schematic diagram of the structure in which the electrode connection device and the antenna are installed inside the top cover body.

FIG. 6 is a schematic diagram of the structure of FIG. 5 after removing the electrode connection device and the antenna.

FIG. 7 is a rear view of FIG. 6 .

FIG. 8 is a perspective view of an elastic cap.

FIG. 9 is a cross-sectional view of FIG. 8 .

FIG. 10 is a schematic diagram of the structure of the pulse generator of the present invention fixed on the skull.

FIG. 11 is a cross-sectional view of FIG. 10 .

FIG12 is a schematic diagram of the overall structure of the pulse generator in Example 2 of the present invention.

FIG. 13 is a schematic exploded view of the structure of FIG. 12 .

FIG. 14 is a schematic diagram of the exploded structure of the top cover component in FIG. 13 .

FIG. 15 is a schematic diagram of the structure in which the electrode connection device and the antenna are installed inside the top cover body.

FIG. 16 is a rear view of FIG. 15 .

FIG. 17 is a schematic diagram of the structure of the neural stimulation system fixedly installed on the human skull.

FIG. 18 is a schematic diagram of the implantation process of the implantable neural stimulation system.

Reference numerals: 1, top cover component; 11, top cover body; 12, mounting position 13, second fixing hole; 14, elastic cap; 15, normally closed opening; 16, accommodating groove; 17, mounting gap; 18, recess; 101, first limiting groove; 102, second limiting groove; 103, groove; 104, fixed pressing plate; 105, pin hole; 2, main body component; 21, housing; 22, feed-through wire; 3, electrode connecting device; 31, first electrode connecting device; 32, second electrode connecting device; 301, connector; 302, insulating ring; 303, wiring slot; 304, first positioning and mounting portion; 305, second positioning and mounting portion; 306, jack; 307, first fixing hole; 4, charging coil; 40, opening slot; 41, first lead end; 42, second lead end; 5, antenna; 6, electrode wire; 7, pressing piece; 8, skull; 81, bone cement; 9, mounting shell; 91, mounting lug; 92, screw; 93, bending pressure plate; 100, pulse generator; 200, extracorporeal control device; 300, fixing device.

DETAILED DESCRIPTION

The technical solution of the present invention is described in detail below in conjunction with the accompanying drawings.

Example 1

This embodiment provides a pulse generator with a single-side wiring slot, as shown in Figures 1-3, comprising: a top cover component 1, including a top cover body 11, and an electrode connection device 3 installed inside the top cover body 11 (in this embodiment, there are two electrode connection devices 3, namely a first electrode connection device 31 and a second electrode connection device 32); a main body component 2, including a shell 21, a circuit board installed inside the shell 21 (not shown in the figure), and a feed-through wire 22 electrically connected to the circuit board; the feed-through wire 22 is used to be inserted into the top cover component 11 and electrically connected to the electrode connection device 3; two electrode connection devices 3 are provided inside the top cover body 11, and are arranged in parallel in a direction away from the main body component 2. The feed-through wire 22 is divided into two categories, one is straight and short in Figure 2, used to be electrically connected to the first electrode connection device 31, and the other is curved and long in Figure 2, used to be electrically connected to the second electrode connection device 32.

The pulse generator of this embodiment adjusts the arrangement of the electrode connection device 3 inside the top cover component 1, reduces the thickness of the top cover component 1, and further reduces the thickness of the entire pulse generator. The pulse generator with the above structural arrangement is lighter and thinner, the depth of the bone groove opened on the skull is shallower, the patient suffers less pain, and the operation is safer.

As shown in FIG5 , the electrode connection device 3 includes a plurality of connectors 301 (four in this embodiment), an insulating ring 302 (four in this embodiment) is provided between two adjacent connectors 301, and the plurality of connectors 301 are respectively used to contact and connect with different connection positions of the insertion end of the electrode wire 6 to send stimulation signals to different contact points of the electrode wire 6, and the connectors 301 are provided with wiring slots 303; all the wiring slots 303 of the electrode connection device 3 are arranged toward the same side of the top cover component 1. FIG5 shows that all of them are facing the front side of the paper.

The above-mentioned arrangement of all the wiring slots of the electrode connecting device 3 facing one side facilitates the feed-through wires 22 to extend from one side of the main body part 2 to the inside of the top cover part 1, enter the wiring slots 303 and electrically connect with the connector 301, thereby reducing the connection interference of the components inside the top cover part 1, thereby facilitating the thinning of the thickness of the top cover part 1.

Correspondingly, the feed-through wire 22 extends from the recessed position 18 on the same side of the shell 21 as the wiring slot 303, and then is inserted into the top cover component 1 to be electrically connected to the corresponding wiring slot 303, the charging coil 4, and the antenna 5, respectively. This way of outlet of the feed-through wire 22, which is concentrated from one side and then extends to the top cover component 1 from different positions, not only avoids the problem of complicated wiring and wiring caused by the outlet of the main body component 2 on the side facing the top cover component 1, but also facilitates the lightweight manufacturing of the main body component 2. As long as the feed-through wire 22 can be concentrated from the recessed position 18 on one side of the main body component 2, no matter how closely it is arranged inside the main body component 2, it will not affect the subsequent electrical connection with the top cover component 1, so it is conducive to compactness during design and manufacturing.

As shown in FIG5 , the top cover component 1 is provided with a plurality of first limiting grooves 101, and the first limiting grooves 101 are directly opposite to the wiring groove 303 of the electrode connection device 3 (i.e., the first electrode connection device 31 shown in the figure) closest to the main body component 2, and a portion of the feed-through wire 22 passes through the first limiting groove 101 and directly extends into the wiring groove 303 of the first electrode connection device 31 to connect with the connector 301. In this way, after the feed-through wire 22 extends from the main body component 2, it directly enters the interior of this part of the wiring groove 303 through the first limiting groove 101 to achieve electrical connection, and the line is short, and almost no internal space of the top cover component 1 is occupied.

The top cover component 1 is also provided with a plurality of second limiting grooves 102, which are not directly opposite to the connector 301 of the first electrode connecting device 31. After another part of the feed-through wire 22 passes through the second limiting groove 102, it goes around the insulating ring 302 and enters between two adjacent electrode connecting devices 3, and then enters the wiring groove 303 of the other electrode connecting device 3 (such as the second electrode connecting device 32 shown in the figure) that is not closest to the main body component 2, and is connected to the connector 301. With this arrangement, after another part of the feed-through wire 22 passes through the second limiting groove 102, it is basically directly opposite to the insulating ring 302 (or it can be other positions close to the connector 301), avoiding electrical connection with the connector 301 of the first electrode connecting device 31; after passing through the insulating ring 302, it enters between two adjacent electrode connecting devices 3 (i.e., the first electrode connecting device 31 and the second electrode connecting device 32 shown in the figure). When the electrode connecting device 3 is fixed, this part of the feed-through wire 22 is compacted between the insulating ring 32 and the inner wall of the top cover body 11. This wiring method makes full use of the gap space inside the top cover component 1, and the line wiring is regular and firmly fixed.

As shown in FIG6 , the electrode connection device 3 has a first positioning and mounting portion 304 and a second positioning and mounting portion 305. The top cover body 1 is provided with a mounting position 12 for positioning and mounting the first positioning and mounting portion 304 and the second positioning and mounting portion 305; the connector 301 and the insulating ring 302 are arranged between the first positioning and mounting portion 304 and the second positioning and mounting portion 305. The first positioning and mounting portion 304 and the second positioning and mounting portion 305 are positioned and mounted inside the top cover body 11, so that the entire electrode connection device 3 can be positioned and mounted, and the remaining space can provide a wiring path for the feed-through wire 22.

As shown in Fig. 4, Fig. 6, Fig. 8 and Fig. 9, the second positioning and mounting part 305 is provided with a first fixing hole 307 which is connected with the insertion hole 306 of the electrode connection device 3 for inserting and installing the electrode wire 6; the top cover body 11 is provided with a second fixing hole 13 opposite to the first fixing hole 307; an elastic cap 14 is installed at the position of the second fixing hole 13, and the elastic cap 14 is provided with a normally closed opening 15, the second fixing hole 13 is located in the groove 106 of the top cover body 11, and the groove 19 is used to fill the sealant around the elastic cap 14; a fixing bolt passes through the second fixing hole 13 and is screwed with the first fixing hole 307, and is used to squeeze the electrode wire 6 inserted into the inside of the insertion hole 306. When in use, a tool is used to pass through the normally closed opening 15 of the elastic cap 14, cooperate with the fixing bolt, and the fixing bolt is turned to rotate, and it is extended relative to the first fixing hole 307, thereby tightening or releasing the electrode wire 6 inserted into the inside of the insertion hole 306.

As shown in Fig. 4 and Fig. 7, a side of the top cover body 11 away from the electrode connection device 3 is provided with a receiving groove 16 for receiving and installing the charging coil 4; the side of the receiving groove 16 facing the main body 2 is provided with an opening groove 40 for the charging coil 4 to pass through and connect to the main body 2. The charging coil 4 is installed in this position, and after the pulse generator is implanted in the human body, this position faces outward, which is convenient for charging with an external charger; the opening groove 40 provides a line path for the power supply coil 4 to communicate with the main body 2.

Furthermore, the charging coil 4 is coated with silicone rubber, which not only fixes the charging coil 4 but also does not generate interference such as eddy current during charging, thereby improving the charging efficiency.

As shown in Fig. 4-6, an antenna 5 is also included, which is arranged in the installation gap 17 formed between the end of the top cover body 11 away from the main body 2 and the electrode connecting device 3. This assembly method makes full use of the installation space of the top cover body 1 and is conducive to the interaction of antenna 5 with external signals.

As shown in FIG4 , a groove 103 is provided on the outer wall of the top cover body 11 at one end away from the main body part 2, and a fixed pressing plate 104 is provided inside the groove 103. Its specific application is shown in FIG10 , when the pulse generator is installed on the human skull, a screw is used to fix one end of the pressing plate 7 at the skull position opposite to the groove 103, and the other end of the pressing plate 7 is pressed on the fixed pressing plate 104 position, thereby fixing the pulse generator.

In this embodiment, the top cover component 1 and the main body component 2 are fixedly connected by means of sleeve clamping. As shown in Figure 2, three pins 23 are provided at one end of the main body component 2 facing the top cover component 1, and a cavity is provided at the bottom of the top cover component 1 for inserting the end of the main body component 2. A pin hole 105 is provided on the inner wall at the corresponding position of the cavity. When the top cover component 1 and the main body component 2 are assembled, the end of the main body component 2 extends into a part of the bottom cavity of the top cover component 1, and then the three pins 23 are respectively passed through the three corresponding pin holes 105 positions to complete the fixed clamping.

In this embodiment, the pulse generator is installed inside the bone groove of the skull 8 through an installation device, as shown in Figure 10. First, the installation shell 9 is placed inside the bone groove. The installation lug 91 on the installation shell 9 is provided with a mounting hole. The screw 92 is used to screw into the skull 8 from the mounting hole position to complete the fixed installation of the installation shell 9; then the pulse generator is placed inside the installation shell 9. One end of the installation shell 9 is provided with a bent pressure plate 93. An installation space is formed between the bent pressure plate 93 and the installation shell 9. One end of the pulse generator extends into the installation space and is squeezed and fixed by the installation shell 9 and the bent pressure plate 93. The other end of the pulse generator is provided with the above-mentioned groove 103 and one end of the fixed pressure plate 104. One end of the pressure plate 7 is fixed to the skull with a screw, and the other end of the pressure plate 7 is pressed on the fixed pressure plate 104 position, thereby fixing the other end of the pulse generator, thereby realizing the installation of the pulse generator inside the skull. In the pulse generator of this embodiment, after the above installation is completed, the first electrode connecting device 31 and the second electrode connecting device 32 are arranged inside the bone groove in a non-overlapping flat manner, and the required bone groove depth is shallow.

Example 2

The present embodiment provides a pulse generator with wiring slots arranged on both sides, comprising: a top cover component 1, comprising a top cover body 11, and an electrode connecting device 3 installed inside the top cover body 11; a main body component 2, comprising a shell 21, a circuit board installed inside the shell 21, and a feed-through wire 22 electrically connected to the circuit board; the feed-through wire 22 is used to be inserted into the top cover component 11 and electrically connected to the electrode connecting device 3; two electrode connecting devices 3 are arranged inside the top cover body 11, and are arranged in parallel in a direction away from the main body component 2; the electrode connecting device 3 comprises a plurality of connectors 301, an insulating ring 302 is arranged between two adjacent connectors 301, and wiring slots 303 are arranged on each of the connectors 301; the wiring slot 303 of one electrode connecting device 3 is arranged toward one side of the top cover component 1; the wiring slot 303 of another electrode connecting device 3 is arranged toward the other side of the top cover component 1.

The pulse generator of this embodiment adjusts the arrangement of the electrode connection device 3 inside the top cover component 1, reduces the thickness of the top cover component 1, and further reduces the thickness of the entire pulse generator. The wiring slot 303 of one electrode connection device 3 is set toward one side of the top cover component 1, and the wiring slot 303 of the other electrode connection device 3 is set toward the other side of the top cover component 1, so that the feed-through wire 22 extends from one side of the main body component 2 to the inside of the top cover component 1, and then directly enters the wiring slot 303 to be electrically connected to the connector 301, thereby reducing the thickness of the top cover component 1. The pulse generator of this embodiment is thinner and lighter, and the depth of the bone groove opened on the skull is shallower, the patient suffers less pain, and the operation is safer.

The feedthrough wires 22 extend from a side of the housing 21 facing the top cover component 1 , and are then inserted into the top cover component 1 to be electrically connected to corresponding wiring slots 303 .

A plurality of first limiting grooves 101 are provided on one side of the top cover component 1, and the first limiting grooves 101 are directly opposite to a wiring groove 303 of the electrode connecting device 3, and a portion of the feed-through wires 22 pass through the first limiting grooves 101 and directly extend into the wiring groove 303 of the electrode connecting device 3 to be connected with the connector 301.

A plurality of second limiting grooves 102 are provided on the other side of the top cover component 1, and the second limiting grooves 102 are directly opposite to the connector 301 of the other electrode connecting device 3. After another part of the feed-through wire 22 passes through the second limiting grooves 102, it enters the wiring groove 303 of the other electrode connecting device 3 and is connected to the connector 301.

The electrode connecting device 3 has a first positioning and mounting portion 304 and a second positioning and mounting portion 305 , and a mounting position 12 for positioning and mounting the first positioning and mounting portion 304 and the second positioning and mounting portion 305 is provided inside the top cover body 1 ; the connector 301 and the insulating ring 302 are arranged between the first positioning and mounting portion 304 and the second positioning and mounting portion 305 .

The second positioning and mounting portion 305 is provided with a first fixing hole 307 which is connected to the socket 306 of the electrode connecting device 3 for inserting and mounting the electrode wire 6; a second fixing hole 13 is provided on the top cover body 11 opposite to the first fixing hole 307; an elastic cap 14 is installed at the position of the second fixing hole 13, and a normally closed opening 15 is provided on the elastic cap 14; a fixing bolt passes through the second fixing hole 13 and is screwed to the first fixing hole 307, so as to tighten the electrode wire 6 inserted into the socket 306.

During specific use, a tool is used to pass through the normally closed opening 15 of the elastic cap 14 and cooperate with the fixing bolt. The fixing bolt is turned to rotate and expand relative to the first fixing hole 307, thereby tightening or releasing the electrode wire 6 inserted into the inside of the plug hole 306.

A side surface of the top cover body 11 away from the electrode connection device 3 is provided with a receiving groove 16 for receiving and installing the charging coil 4. The charging coil 4 is installed at this position, and after the pulse generator is implanted in the human body, this position faces outward, which is convenient for charging with an external charger.

The charging coil 4 is covered with silicone rubber, which not only fixes the charging coil 4 but also does not generate interference such as eddy current during charging, thereby improving the charging efficiency.

It also includes an antenna 5, which is arranged at one end of the top cover body 11 away from the main part 2 and inside the installation gap 17 formed between the electrode connecting device 3. This assembly method fully utilizes the installation space of the top cover body and is conducive to the signal interaction between the antenna and the outside world.

Example 3

The present embodiment provides an implantable neural stimulation system, as shown in FIG17 , comprising: a pulse generator 100; an electrode wire 6, one end of which has a connection contact for connecting to the pulse generator, and the other end of which has a stimulation contact suitable for connecting to a nerve; a fixing device 300, used to fix the electrode wire 6 to the skull; an external control device 200, capable of wirelessly communicating with the pulse generator; the pulse generator is the pulse generator described in Example 1 or Example 2.

The implantable neural stimulation system of this embodiment, since it adopts the pulse generator in Example 1 or Example 2, naturally has all the advantages brought by adopting the above-mentioned pulse generator, such as good lightness, high charging efficiency, etc.

FIG18 is a schematic diagram of the implantation process of the implantable neural stimulation system of the present invention. First, step s00 is performed. According to the traditional method, a hole is opened in the skull, the stimulation electrode is implanted and the electrode is fixed. After the electrode is tested to be normal, step s01 is performed; the scalp is cut at the location where the pulse generator 100 is installed to expose the skull, and a skull bone groove is prepared according to the shape of the pulse generator 100; then step s02 is performed, the pulse generator installation shell 9 is placed and fixed to the skull; then step s03 is performed, a subcutaneous tunnel is created between the pulse generator incision and the electrode incision, and the connecting end of the electrode wire 6 is passed through the subcutaneous tunnel to reach the implantation position of the pulse generator 100. The excess electrode wire 6 can be wrapped around the electrode fixing device 300 for several turns. Then step s04 is performed to connect the electrode and the pulse generator 100 and lock them; then step s05 is performed to fix the pulse generator 100 on the installation shell 9. Finally, step s06 is performed to test the implantation system with an in vitro programmer. After the test is normal, the incision is sutured to complete the implantation.

Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the invention.

Claims (8)

1. A pulse generator with a wiring trough single-sided arrangement, comprising:

a cap member (1) including a cap body (11), and an electrode connection device (3) mounted inside the cap body (11);

A body member (2) including a housing (21), a circuit board mounted inside the housing (21), and a feed-through wire (22) electrically connected to the circuit board; the feed-through wire (22) is used for being inserted into the top cover part (1) to be electrically connected with the electrode connecting device (3);

the method is characterized in that: the electrode connecting device (3) is provided with at least two inside the top cover body (11) and is arranged in parallel towards the direction away from the main body part (2);

The electrode connecting device (3) comprises a plurality of connectors (301), an insulating ring (302) is arranged between two adjacent connectors (301), and wiring grooves (303) are formed in each connector (301);

all the connection slots (303) of the electrode connection means (3) are arranged towards the same side of the cover member (1);

The feed-through wires (22) extend out from the concave (18) position at one side of the shell (21) and are inserted into the top cover part (1) to be electrically connected with the corresponding wiring grooves (303) respectively;

A plurality of first limit grooves (101) are formed in the top cover part (1), the first limit grooves (101) are opposite to the wiring grooves (303) of the electrode connecting device (3) closest to the main body part (2), and a part of feed-through wires (22) penetrate through the first limit grooves (101) and then directly extend into the wiring grooves (303) of the electrode connecting device (3) closest to the main body part (2) to be connected with the connector (301);

The top cover part (1) is also provided with a plurality of second limit grooves (102), the second limit grooves (102) are not opposite to the connectors (301) of the electrode connecting devices (3) closest to the main body part (2), and after the other part of feed-through wires (22) pass through the second limit grooves (102), the feed-through wires enter between the two adjacent electrode connecting devices (3) by bypassing the insulating ring (302) and then enter the inside of the wiring grooves (303) of the other electrode connecting devices (3) not closest to the main body part (2) to be connected with the connectors (301);

The thickness of the main body part (2) is basically the same as that of the top cover part (1), and the thickness of the main body part (2) is larger than that of one electrode connecting device (3) and smaller than that of two electrode connecting devices (3).

2. The pulse generator of claim 1, wherein: the electrode connecting device (3) is provided with a first positioning installation part (304) and a second positioning installation part (305), and an installation position (12) for positioning and installing the first positioning installation part (304) and the second positioning installation part (305) is arranged in the top cover body (11); the connector (301) and the insulating ring (302) are disposed between the first positioning mounting portion (304) and the second positioning mounting portion (305).

3. The pulse generator of claim 2, wherein: the second positioning and mounting part (305) is provided with a first fixing hole (307) communicated with an inserting hole (306) of the electrode connecting device (3) for inserting and mounting the electrode wire (6);

a second fixing hole (13) is formed in the top cover body (11) opposite to the first fixing hole (307);

an elastic cap (14) is arranged at the position of the second fixing hole (13), and a normally closed opening (15) is arranged on the elastic cap (14);

The fixing bolt passes through the second fixing hole (13) and then is in threaded connection with the first fixing hole (307) and is used for tightly pressing the electrode lead (6) inserted into the jack (306).

4. The pulse generator of claim 1, wherein: a containing groove (16) for containing and installing the charging coil (4) is arranged on one side surface of the top cover body (11) which is far away from the wiring groove (303) of the electrode connecting device (3); an open slot (40) used for the charging coil (4) to penetrate out to be connected with the main body part (2) is arranged on one side of the accommodating groove (16) facing the main body part (2).

5. The pulse generator of claim 4, wherein: the charging coil (4) is coated with silicone rubber.

6. The pulse generator of claim 1, wherein: the device also comprises an antenna (5) which is arranged in an installation gap (17) formed between one end of the top cover body (11) which is far away from the main body part (2) and the electrode connecting device (3).

7. The pulse generator of claim 1, wherein: the top cover comprises a top cover body (11), wherein a groove (103) is formed in the outer wall of one end, far away from the main body part (2), of the top cover body, and a fixed pressing plate (104) is arranged in the groove (103).

8. An implantable neurostimulation system comprising:

a pulse generator;

An electrode lead (6) having a connection contact at one end for connection to the pulse generator and a stimulation contact at the other end adapted for connection to a nerve;

a fixing device for fixing the electrode lead (6) to the skull;

An in vitro control device capable of wireless communication with the pulse generator;

the method is characterized in that:

The pulse generator is a pulse generator as claimed in any one of claims 1 to 7.