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CN112345025A - Liquid level detection device and liquid-transfering gun - Google Patents

Liquid level detection device and liquid-transfering gun Download PDF

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Publication number
CN112345025A
CN112345025A CN202011294524.8A CN202011294524A CN112345025A CN 112345025 A CN112345025 A CN 112345025A CN 202011294524 A CN202011294524 A CN 202011294524A CN 112345025 A CN112345025 A CN 112345025A
Authority
CN
China
Prior art keywords
air
outlet pipe
liquid
air outlet
liquid level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202011294524.8A
Other languages
Chinese (zh)
Inventor
喻蓉
喻鹏
刘晓华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Changsha Yixiuxing Intelligent Technology Co ltd
Original Assignee
Changsha Yixiuxing Intelligent Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Changsha Yixiuxing Intelligent Technology Co ltd filed Critical Changsha Yixiuxing Intelligent Technology Co ltd
Publication of CN112345025A publication Critical patent/CN112345025A/en
Withdrawn legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/22Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0213Accessories for glass pipettes; Gun-type pipettes, e.g. safety devices, pumps

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Thermal Sciences (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Measurement Of Levels Of Liquids Or Fluent Solid Materials (AREA)

Abstract

The invention relates to a liquid level detection device and a liquid transfer gun, which comprise an air source, an air inlet pipe, a first air outlet pipe, a second air outlet pipe, a flow sensor and a control system, wherein the air source provides air with stable flow, the air inlet pipe is connected with the first air outlet pipe and the second air outlet pipe, the outlet of the first air outlet pipe is arranged in the liquid transfer gun body and faces the direction of mounting a gun head at the lower part of the gun body, the outlet of the second air outlet pipe is arranged outside the liquid transfer gun body, the flow sensor is arranged on the second air outlet pipe, the air inlet pipe and the second air outlet pipe penetrate through the side wall of the liquid transfer gun body and are tightly matched, and the control system is used for detecting signals of the flow sensor, controlling the air source and outputting liquid level detection signals. The invention can ensure that the gun body does not contact the solution detection liquid level position so as to accurately control the depth of the gun head inserted into the solution, and is suitable for automation.

Description

Liquid level detection device and liquid-transfering gun
Technical Field
The invention relates to the technical field of liquid filling, in particular to a liquid level detection device and a liquid-transferring gun.
Background
The pipette is one of the common instruments in biological, medical and chemical laboratories, and is commonly used for precise extraction of small or trace amounts of liquid in the laboratory. In order to ensure accurate pipetting volumes, minimize experimental errors and achieve good reproducibility, special attention is paid to the method of use of the pipetting gun and to the considerations:
1. the pipette is required to vertically suck liquid when sucking liquid, and the liquid transfer is inaccurate due to excessive inclination of the pipette;
2. the suction head is immersed into the liquid with proper depth, the gun head is generally inserted 2-3 mm below the liquid level, the liquid suction process is kept unchanged as much as possible, the gun head is inserted too deeply, and the liquid suction precision is influenced by overlarge liquid pressure;
3. when liquid is sucked, the thumb must be loosened slowly and stably, and the liquid sucking speed is too high, so that backflushing and bubbles can be generated, and the liquid-sucking volume is inaccurate;
4. slowly sucking and slowly releasing, and slowly sucking and releasing liquid at a constant speed, so that the accuracy of a result is ensured.
In the prior art, a pipette is manually operated, and the liquid level is observed by naked eyes, so that the depth of the pipette head inserted into liquid is unstable, the pipette head is inserted too deeply, the liquid suction precision is influenced by overlarge pressure of the liquid, and the pipette head is inserted too shallowly and easily sucks air and also influences the liquid suction precision.
Disclosure of Invention
In view of the above problems, the present invention provides a liquid level detection device and a pipette, which can detect the position of the liquid level of a solution without contacting the solution with the body of the pipette, so as to precisely control the insertion depth of the pipette tip into the solution, reduce the influence on the result accuracy due to manual operation, and are particularly suitable for automatic pipetting devices.
The technical scheme adopted by the invention for solving the technical problems is as follows: the liquid level detection device comprises an air source, an air inlet pipe, a first air outlet pipe, a second air outlet pipe, a flow sensor and a control system, wherein the air source provides air with stable flow, the air inlet pipe is connected with the first air outlet pipe and the second air outlet pipe, the outlet of the first air outlet pipe is arranged in a liquid-transferring gun body and faces the direction of a gun head mounted at the lower part of the gun body, the outlet of the second air outlet pipe is arranged outside the liquid-transferring gun body, the flow sensor is mounted on the second air outlet pipe, the air inlet pipe and the second air outlet pipe penetrate through the side wall of the liquid-transferring gun body and are tightly matched, and the control system is used for detecting signals of the flow sensor, controlling the air source and outputting liquid level detection signals.
Preferably, the air inlet pipe is provided with a first one-way valve, and air can only enter but not exit.
Preferably, the second air outlet pipe is provided with a second one-way valve, and air can only be discharged but not enter.
Preferably, the liquid level detection device further comprises a middle pipe, one end of the middle pipe is connected with the outlet of the first air outlet pipe, and the other end of the middle pipe is connected with the second air outlet pipe.
Preferably, the middle pipe is provided with a third one-way valve, and gas can only flow from the first gas outlet pipe to the second gas outlet pipe.
Preferably, the air source and the flow sensor are arranged outside the liquid-transfering gun body.
The invention also provides a liquid transferring gun which is provided with the liquid level detection device.
Compared with the prior art, the invention has the following beneficial effects:
1. the liquid level of the solution can be automatically detected under the condition that the gun body is not contacted with the solution, the solution is not polluted, and the depth of the gun head inserted into the solution is accurately controlled;
2. is suitable for automation and reduces the labor intensity of operators.
Drawings
FIG. 1 is a schematic structural diagram of a first embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a second embodiment of the present invention;
FIG. 3 is a schematic structural diagram of a third embodiment of the present invention;
FIG. 4 is a schematic structural diagram of a fourth embodiment of the present invention;
FIG. 5 is a schematic structural diagram of a fifth embodiment of the present invention;
fig. 6 is a schematic structural diagram of a sixth embodiment of the present invention.
Detailed Description
The present invention will be described in detail with reference to fig. 1 to 6, and the exemplary embodiments and descriptions of the present invention are provided to explain the present invention, but not to limit the present invention.
The first embodiment is as follows:
the utility model provides a liquid level detection device, refer to fig. 1, including wind source 1, intake pipe 3, first outlet duct 4, second outlet duct 8, flow sensor 9 and control system 10, wind source 1 provides the air of flow stability, intake pipe 3 and first outlet duct 4, second outlet duct 7 links to each other, the export of first outlet duct 4 is established in the liquid-transfering gun rifle body 12, towards rifle head 11 direction, the export of second outlet duct 8 is established outside liquid-transfering gun rifle body 12, flow sensor 9 installs on second outlet duct 8, intake pipe 3 and second outlet duct 8 pass liquid-transfering gun rifle body 12 lateral wall and closely cooperate, control system 10 is used for detecting flow sensor 9's signal, control wind source 1 and output liquid level detection signal, wind source 1 and flow sensor 9 are installed in the liquid-transfering gun rifle body 12 outside, rifle head 11 is installed in liquid-transfering gun rifle body 12 lower part.
The specific control method of the control system 10 is the prior art, and the present invention only needs to realize specific functions, which is not described in detail herein.
In the specific implementation process, the liquid level detection comprises the following implementation steps: the liquid transferring gun body 12 and the gun head 11 move downwards under the manual control or the automatic control, the gun head 11 contacts the liquid level, the first path of air is blocked, the resistance is increased, the flow rate of the first path of air is reduced, the flow rate of the second path of air is increased, the numerical value transmitted to the control system 10 from the flow sensor 9 is increased, the control system 10 judges that the gun head contacts the liquid level at the moment, the control system 10 controls the air source 1 to be closed, and meanwhile, a liquid level detection signal is output to be used by the manual control or the automatic control system.
Example two:
the difference between this embodiment and the first embodiment is:
referring to fig. 2, the air inlet pipe 3 is provided with a first one-way valve 2, air can only enter but not exit, and a larger opening pressure is set to ensure that the first one-way valve 2 cannot be opened when the pipette sucks liquid, and the second air outlet pipe 8 is provided with a second one-way valve 7, so that air can only exit but not enter;
when two check valves can guarantee the imbibition of the pipette, the outside air can not enter the internal containing cavity of the pipette body 7 through the air inlet pipe 3 and the second air outlet pipe 8, and the precision of the imbibition solution is guaranteed.
Example three:
the difference between this embodiment and the first embodiment is:
referring to fig. 3, the gas-liquid separator further comprises a middle pipe 6, wherein one end of the middle pipe 6 is connected with an outlet of the first gas outlet pipe 4, and the other end of the middle pipe 6 is connected with a second gas outlet pipe 8;
when the gun head 11 contacts the liquid level, the first path of air is blocked, the resistance is increased, the flow of the first path of air is reduced, the flow of the second path of air is increased, the flow rate of the first air outlet pipe 4 is small, the pressure at one end of the middle pipe 6 connected with the first air outlet pipe 4 is large, the flow rate of the second air outlet pipe 8 is large, and the pressure at one end of the middle pipe 6 connected with the second air outlet pipe 8 is small, so that the first path of air flows to the second air outlet pipe 7 through the middle pipe 6, the increase of the flow of the second air outlet pipe 8 is more obvious, the signal transmitted to the control system 10 by the flow sensor 9 is more reliable, and the air pressure increased by.
Example four:
the difference between this embodiment and the third embodiment is that:
referring to fig. 4, the middle tube 6 is provided with a third check valve 5, and gas can only flow from the first outlet tube 4 to the second outlet tube 8.
Example five:
the difference between this embodiment and the third embodiment is that:
referring to fig. 5, the air inlet pipe 3 is provided with a first one-way valve 2, air can only enter and can not exit, and a larger opening pressure is set, so that the first one-way valve 2 can not be opened when the pipette sucks liquid, and the second air outlet pipe 8 is provided with a second one-way valve 7, so that air can only exit and can not enter.
Example six:
the present embodiment is different from the fourth embodiment in that:
referring to fig. 6, the air inlet pipe 3 is provided with a first one-way valve 2, air can only enter and can not exit, and a larger opening pressure is set, so that the first one-way valve 2 can not be opened when the pipette sucks liquid, and the second air outlet pipe 8 is provided with a second one-way valve 7, so that air can only exit and can not enter.
Example seven:
the invention also provides a liquid transferring gun which is provided with the liquid level detection device.
The technical solutions provided by the embodiments of the present invention are described in detail above, and the principles and embodiments of the present invention are explained herein by using specific examples, and the descriptions of the embodiments are only used to help understanding the principles of the embodiments of the present invention; meanwhile, for a person skilled in the art, according to the embodiments of the present invention, there may be variations in the specific implementation manners and application ranges, and in summary, the content of the present description should not be construed as a limitation to the present invention.

Claims (7)

1. A liquid level detection device is characterized in that: the liquid transferring gun comprises an air source, an air inlet pipe, a first air outlet pipe, a second air outlet pipe, a flow sensor and a control system, wherein the air source provides air with stable flow, the air inlet pipe is connected with the first air outlet pipe and the second air outlet pipe, the outlet of the first air outlet pipe is arranged in a liquid transferring gun body and faces the direction of a gun head mounted at the lower part of the gun body, the outlet of the second air outlet pipe is arranged outside the liquid transferring gun body, the flow sensor is mounted on the second air outlet pipe, the air inlet pipe and the second air outlet pipe penetrate through the side wall of the liquid transferring gun body and are tightly matched, and the control system is used for detecting signals of the flow sensor, controlling the air source and outputting liquid level detection signals.
2. The liquid level detection device according to claim 1, characterized in that: the air source and the flow sensor are arranged on the outer side of the liquid-transfering gun body.
3. The liquid level detection device according to claim 1, characterized in that: the air inlet pipe is provided with a first one-way valve, and air can only enter but not exit.
4. The liquid level detection device according to claim 1, characterized in that: and the second air outlet pipe is provided with a second one-way valve, and air can only be discharged but not enter.
5. The liquid level detection device according to claim 1, characterized in that: the gas-liquid separator further comprises a middle pipe, wherein one end of the middle pipe is connected with the outlet of the first gas outlet pipe, and the other end of the middle pipe is connected with the second gas outlet pipe.
6. The liquid level detection device according to claim 5, characterized in that: the middle pipe is provided with a third one-way valve, and gas can only flow from the first gas outlet pipe to the second gas outlet pipe.
7. A pipette, characterized by: a liquid level detecting device according to any one of claims 1 to 6.
CN202011294524.8A 2020-08-11 2020-11-18 Liquid level detection device and liquid-transfering gun Withdrawn CN112345025A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010799419 2020-08-11
CN2020107994193 2020-08-11

Publications (1)

Publication Number Publication Date
CN112345025A true CN112345025A (en) 2021-02-09

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116448208A (en) * 2023-04-07 2023-07-18 南京医科大学 Pneumatic liquid level depth detection method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63109373A (en) * 1986-10-27 1988-05-14 Kyoto Daiichi Kagaku:Kk Sampling method and apparatus therefor
JPH06273426A (en) * 1993-03-18 1994-09-30 Horiba Ltd Liquid-surface detection device and liquid-surface detection method using the device
CN109718883A (en) * 2018-12-25 2019-05-07 迪瑞医疗科技股份有限公司 A kind of liquid-transfering device and liquid relief method
CN209669258U (en) * 2019-01-28 2019-11-22 北京致雨生物科技有限公司 A kind of digital pcr droplet generation system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63109373A (en) * 1986-10-27 1988-05-14 Kyoto Daiichi Kagaku:Kk Sampling method and apparatus therefor
JPH06273426A (en) * 1993-03-18 1994-09-30 Horiba Ltd Liquid-surface detection device and liquid-surface detection method using the device
CN109718883A (en) * 2018-12-25 2019-05-07 迪瑞医疗科技股份有限公司 A kind of liquid-transfering device and liquid relief method
CN209669258U (en) * 2019-01-28 2019-11-22 北京致雨生物科技有限公司 A kind of digital pcr droplet generation system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
(美)基利安: "《现代控制技术 组件与系统》", 31 March 2010 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116448208A (en) * 2023-04-07 2023-07-18 南京医科大学 Pneumatic liquid level depth detection method
CN116448208B (en) * 2023-04-07 2025-07-25 南京医科大学 Pneumatic liquid level depth detection method

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Application publication date: 20210209

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