CN112363447A - A fully automatic chromatography equipment based on ARM chip - Google Patents
A fully automatic chromatography equipment based on ARM chip Download PDFInfo
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- CN112363447A CN112363447A CN202011222502.0A CN202011222502A CN112363447A CN 112363447 A CN112363447 A CN 112363447A CN 202011222502 A CN202011222502 A CN 202011222502A CN 112363447 A CN112363447 A CN 112363447A
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- arm
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- pump
- sensor
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- 238000004587 chromatography analysis Methods 0.000 title claims abstract description 15
- 238000000746 purification Methods 0.000 description 5
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
- G05B19/05—Programmable logic controllers, e.g. simulating logic interconnections of signals according to ladder diagrams or function charts
- G05B19/054—Input/output
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B2219/00—Program-control systems
- G05B2219/10—Plc systems
- G05B2219/11—Plc I-O input output
- G05B2219/1103—Special, intelligent I-O processor, also plc can only access via processor
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Automation & Control Theory (AREA)
- Temperature-Responsive Valves (AREA)
Abstract
本发明提供了一种全自动层析系统，包括依次网络连接的上位机、路由器、arm板微型电脑；所述路由器分别与arm主、arm备、arm从A、arm从B、arm从C、arm从D、arm从E进行连接；所述arm从A与泵A、泵B、泵C单元连接，arm从B与阀1、阀2、阀3、阀4、阀5单元连接、arm从C与pH传感器、电导传感器、UV检测器单元连接，arm从D与温度传感器、压力传感器、运行/暂停按钮、两位三通阀、指示灯单元连接，arm从E与串口RS232、串口RS485、其它通讯设备单元连接。arm从A、arm从B、arm从C、arm从D、arm从E不限于和单一同种设备连接，可分别与泵、阀、pH传感器、电导传感器、UV检测器、温度传感器、压力传感器、各种通讯设备混合连接。
The invention provides a fully automatic chromatography system, comprising an upper computer, a router, and an arm board microcomputer connected in sequence through a network; the router is respectively connected to the arm master, the arm backup, the arm slave A, the arm slave B, the arm slave C, The arm is connected from D and arm from E; the arm from A is connected to the units of pump A, pump B, and pump C, and the arm from B is connected to the units of valve 1, valve 2, valve 3, valve 4, and valve 5, and the arm from C is connected with pH sensor, conductivity sensor, UV detector unit, arm is connected with temperature sensor, pressure sensor, run/pause button, two-position three-way valve, indicator light unit from D, arm is connected with serial port RS232, serial port RS485, Other communication equipment units are connected. arm from A, arm from B, arm from C, arm from D, arm from E are not limited to connecting with a single device of the same kind, but can be connected to pumps, valves, pH sensors, conductivity sensors, UV detectors, temperature sensors, and pressure sensors. , Mixed connection of various communication devices.
Description
Technical Field
The invention relates to purification and separation of substances such as protein, natural products and the like, in particular to full-automatic chromatography equipment based on an ARM chip.
Background
In the prior art, a PLC control system is taken as a mainstream, the off-line operation cannot be realized, the expansibility of communication and a network is insufficient, the remote control capability is limited, and the safety is insufficient. The present invention is proposed to solve the above-mentioned drawbacks in the prior art.
Disclosure of Invention
The invention provides full-automatic chromatography equipment based on an ARM chip, which can detect liquid to be purified through a sensor and control a valve body and a pump body required by the purification equipment to automatically operate according to a detection result, so that the purification efficiency is improved, and the purification precision is increased. The system is an industrial personal computer based on an arm framework CPU, a linux operating system is operated, and the system safety can be better ensured in network communication. Meanwhile, multi-device access and remote control can be realized through network connection. The redundancy of an operating system is realized by the online operation of the arm main microcomputer and the arm standby microcomputer, and the reliability and the safety of the operation of the system are improved.
A full-automatic chromatography device based on an ARM chip comprises an upper computer, a router and an ARM board microcomputer which are sequentially connected through a network; the arm board microcomputer comprises an arm main part, an arm spare part, an arm slave part A, arm slave part B, arm slave part C, arm slave part D, arm slave part E;
the router is respectively connected with an arm master, an arm backup and an arm slave A, arm slave B, arm slave C, arm slave D, arm slave E;
the arm is connected with the pump A, the pump B and the pump C from the A, connected with the valve 1, the valve 2, the valve 3, the valve 4 and the valve 5 from the B, connected with the pH sensor, the conductivity sensor and the UV detector unit from the C, connected with the temperature sensor, the pressure sensor, the operation/pause button, the two-position three-way valve and the indicator light unit from the D, and connected with the serial port RS232, the serial port RS485 and other communication equipment units from the E.
Further, in the above-mentioned case,
and the arm board microcomputer is connected with a pump A, a pump B and a pump C from A.
Further, in the above-mentioned case,
the arm board microcomputer is connected with the valve 1, the valve 2, the valve 3, the valve 4 and the valve 5 from the B.
Further, in the above-mentioned case,
the arm board microcomputer is connected with any one or more of a pH sensor, a conductivity sensor and a UV detector from C.
Further, in the above-mentioned case,
the temperature sensor, the at least one pressure sensor, the operation/pause button, the at least one two-position three-way valve and the indicator light are respectively connected with the arm board microcomputer slave D through the I/O control board.
Further, in the above-mentioned case,
the arm board microcomputer is connected with one or more serial ports RS232, one or more serial ports RS485 and other communication equipment from E.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by the practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof as well as the appended drawings.
The technical solution of the present invention is further described in detail by the accompanying drawings and embodiments.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.
In the drawings:
FIG. 1 is a schematic structural diagram of a full-automatic chromatography device based on an ARM chip.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it is to be understood that the preferred embodiments described herein are merely for purposes of illustrating and explaining the present invention and are not intended to limit the present invention.
The embodiment of the invention provides full-automatic chromatography equipment based on an ARM chip, which is shown in a schematic structural diagram in fig. 1 and comprises an upper computer, a router and an ARM board microcomputer which are sequentially connected through a network. The arm board microcomputer comprises an arm main part, an arm spare part, an arm slave part A, arm slave part B, arm slave part C, arm slave part D, arm slave part E;
the router is respectively connected with an arm master, an arm backup and an arm slave A, arm slave B, arm slave C, arm slave D, arm slave E;
the arm is connected with the pump A, the pump B and the pump C from the A, connected with the valve 1, the valve 2, the valve 3, the valve 4 and the valve 5 from the B, connected with the pH sensor, the conductivity sensor and the UV detector unit from the C, connected with the temperature sensor, the pressure sensor, the operation/pause button, the two-position three-way valve and the indicator light unit from the D, and connected with the serial port RS232, the serial port RS485 and other communication equipment units from the E.
The principle and the effect of the technical scheme are as follows:
the full-automatic chromatography equipment based on the ARM chip provided by the invention is powered by a diaphragm pump, is matched with a valve to switch different flow paths, detects various parameters by using a pH sensor, a conductivity sensor, a UV detector, a temperature sensor, a pressure sensor and other detectors, achieves the purpose of differentiation and purification according to the detected parameters, and has the characteristics of full automation, high efficiency, no need of manpower and the like. The equipment takes an arm board microcomputer as a main body, RS232/RS485 as a communication mode, and simultaneously takes the arm board microcomputer as a center for acquiring data and controlling equipment, so that the effects of high efficiency and simple operation can be achieved.
In one embodiment, a pH sensor, a conductivity sensor, a UV detector, a valve 1, a valve 2, a valve 3, a valve 4, a valve 5, a pump a, a pump B, and a pump C are respectively disposed in a vessel, and when the pressure sensor detects that the pressure in the vessel is too high, the arm board microcomputer (main) controls the operation or stop of the valves 1, 2, 3, 4, 5, a pump a, a pump B, and a pump C. And the real-time monitoring data of the pH sensor, the conductivity sensor, the UV detector, the temperature sensor and the pressure sensor can be displayed by an upper computer.
In one embodiment, the arm slave a is connected to pump a, pump B, and pump C units.
In one embodiment, the arm slave B is connected to the valve 1, valve 2, valve 3, valve 4, valve 5 unit.
In one embodiment, the arm slave C is connected to a pH sensor, a conductivity sensor, a UV detector unit.
In one embodiment, the arm slave D is connected with a temperature sensor, a pressure sensor, a run/pause button, a two-position three-way valve and an indicator light unit.
In one embodiment, the arm slave E is connected with a serial port RS232, a serial port RS485 and other communication equipment units.
The system provided by the invention adopts an arm board microcomputer as a main body, and through the operation and monitoring equipment of an upper computer, the detection report can be generated by an upper computer and an arm board microcomputer at the same time, the lower computer takes the arm board microcomputer (main or standby) as a main body and mainly controls the actions and data acquisition of a pH sensor, a conductivity sensor, a UV detector, a pressure sensor, a temperature sensor, all valve bodies and a pump body, a power part is that the arm board microcomputer drives a pump A, a pump B and a pump C to operate from A, the pressure sensor and the temperature sensor transmit analog quantity to an I/O control board, and the upper computer is connected with pH, conductance, UV, pressure and temperature data collected by the arm board microcomputer (a master or slave) through a router and controls the pH, conductance, UV, pressure and temperature data. The pressure and temperature are transmitted to the arm board microcomputer through the I/O control board in an analog quantity form.
It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the invention. Thus, it is intended that the present invention cover the modifications and variations of this invention provided they come within the scope of the appended claims and their equivalents.
Claims (6)
1. A full-automatic chromatography device based on an ARM chip is characterized by comprising an upper computer, a router and an ARM board microcomputer which are sequentially connected through a network, wherein the ARM board microcomputer comprises an ARM main part, an ARM spare part and an ARM slave part A, ARM slave part B, ARM slave part C, ARM slave part D, ARM slave part E;
the router is respectively connected with an arm main device, an arm standby device and an arm slave device A, arm slave device B, arm slave device C, arm slave device D, arm slave device E.
2. The ARM chip based fully automatic chromatography device of claim 1,
and the arm board microcomputer arm is connected with a pump A, a pump B and a pump C from the A.
3. The ARM chip based fully automatic chromatography device of claim 1,
the arm slave B connects valve 1, valve 2, valve 3, valve 4, valve 5.
4. The ARM chip based fully automatic chromatography device of claim 1,
the arm is connected with any one or more of a pH sensor, a conductivity sensor and a UV detector from C.
5. The ARM chip based fully automatic chromatography device of claim 1,
the temperature sensor, the at least one pressure sensor, the operation/pause button, the at least one two-position three-way valve and the indicator light are respectively connected with the arm slave D through the I/O control panel.
6. The ARM chip based fully automatic chromatography device of claim 1,
and the arm slave E is connected with one or more serial ports RS232, one or more serial ports RS485 and other communication equipment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011222502.0A CN112363447A (en) | 2020-11-05 | 2020-11-05 | A fully automatic chromatography equipment based on ARM chip |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011222502.0A CN112363447A (en) | 2020-11-05 | 2020-11-05 | A fully automatic chromatography equipment based on ARM chip |
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| Publication Number | Publication Date |
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| CN112363447A true CN112363447A (en) | 2021-02-12 |
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| CN202011222502.0A Pending CN112363447A (en) | 2020-11-05 | 2020-11-05 | A fully automatic chromatography equipment based on ARM chip |
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Citations (7)
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| US20060027490A1 (en) * | 2004-02-25 | 2006-02-09 | Analogix, Inc. | Chromatography system and method |
| WO2013090972A1 (en) * | 2011-12-23 | 2013-06-27 | University Of Western Sydney | Method for analysing a sample comprising a plurality of analytes |
| CN208351305U (en) * | 2018-07-05 | 2019-01-08 | 广州地铁集团有限公司 | A kind of multi channel signals recorder |
| CN109451021A (en) * | 2018-11-09 | 2019-03-08 | 吾诺瑟斯科技(天津)有限公司 | The more heterogeneous network access systems of Internet of Things edge side and cut-in method |
| CN109634164A (en) * | 2018-11-09 | 2019-04-16 | 苏州赛谱仪器有限公司 | Protein chromatographic control system |
| CN210583779U (en) * | 2019-08-19 | 2020-05-22 | 谱瑞科技(北京)有限公司 | Full-automatic chromatography system |
| CN213240889U (en) * | 2020-11-05 | 2021-05-18 | 北京华创精科生物技术有限公司 | Full-automatic chromatography equipment based on ARM chip |
-
2020
- 2020-11-05 CN CN202011222502.0A patent/CN112363447A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060027490A1 (en) * | 2004-02-25 | 2006-02-09 | Analogix, Inc. | Chromatography system and method |
| WO2013090972A1 (en) * | 2011-12-23 | 2013-06-27 | University Of Western Sydney | Method for analysing a sample comprising a plurality of analytes |
| CN208351305U (en) * | 2018-07-05 | 2019-01-08 | 广州地铁集团有限公司 | A kind of multi channel signals recorder |
| CN109451021A (en) * | 2018-11-09 | 2019-03-08 | 吾诺瑟斯科技(天津)有限公司 | The more heterogeneous network access systems of Internet of Things edge side and cut-in method |
| CN109634164A (en) * | 2018-11-09 | 2019-04-16 | 苏州赛谱仪器有限公司 | Protein chromatographic control system |
| CN210583779U (en) * | 2019-08-19 | 2020-05-22 | 谱瑞科技(北京)有限公司 | Full-automatic chromatography system |
| CN213240889U (en) * | 2020-11-05 | 2021-05-18 | 北京华创精科生物技术有限公司 | Full-automatic chromatography equipment based on ARM chip |
Non-Patent Citations (2)
| Title |
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| 姜海燕 等: "嵌入式AFP测试仪的设计", 《上海生物医学工程》, vol. 27, no. 4, 31 December 2006 (2006-12-31), pages 210 - 213 * |
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Effective date of registration: 20220302 Address after: 310053 room 10007, 1f, No. 6899, Wentao Road, Puyan street, Binjiang District, Hangzhou, Zhejiang Applicant after: Zhejiang Jinyi Shengshi Biological Engineering Co.,Ltd. Address before: 102208 room 1011, 10 / F, block a, Longyu center, building 1, yard 1, Longyu middle street, Huilongguan town, Changping District, Beijing Applicant before: BEIJING HUACHUANG JINGKE BIOTECHNOLOGY Co.,Ltd. |