CN112545607A - Thrombus thrombolysis and suction device - Google Patents
Thrombus thrombolysis and suction device Download PDFInfo
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- CN112545607A CN112545607A CN202011364007.3A CN202011364007A CN112545607A CN 112545607 A CN112545607 A CN 112545607A CN 202011364007 A CN202011364007 A CN 202011364007A CN 112545607 A CN112545607 A CN 112545607A
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- thrombolysis
- catheter
- suction
- thrombus
- cavity
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- 230000002537 thrombolytic effect Effects 0.000 title claims abstract description 109
- 208000007536 Thrombosis Diseases 0.000 title claims abstract description 54
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 31
- 238000011010 flushing procedure Methods 0.000 claims abstract description 25
- 239000003146 anticoagulant agent Substances 0.000 claims description 37
- 238000007789 sealing Methods 0.000 claims description 14
- 239000007924 injection Substances 0.000 claims description 13
- 238000002347 injection Methods 0.000 claims description 13
- 239000003527 fibrinolytic agent Substances 0.000 claims description 5
- 230000037431 insertion Effects 0.000 claims description 5
- 238000003780 insertion Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 7
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 description 6
- 208000006011 Stroke Diseases 0.000 description 5
- 230000000903 blocking effect Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 208000032382 Ischaemic stroke Diseases 0.000 description 2
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000036262 stenosis Effects 0.000 description 2
- 208000037804 stenosis Diseases 0.000 description 2
- 238000013151 thrombectomy Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 208000016988 Hemorrhagic Stroke Diseases 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 208000032851 Subarachnoid Hemorrhage Diseases 0.000 description 1
- 208000032109 Transient ischaemic attack Diseases 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 208000020658 intracerebral hemorrhage Diseases 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000000250 revascularization Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 201000010875 transient cerebral ischemia Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22079—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with suction of debris
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22084—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- External Artificial Organs (AREA)
Abstract
本发明公开了一种血栓溶栓及抽吸装置，包括：抽吸导管，设置于抽吸导管内的溶栓导管；本发明通过抽吸导管和溶栓导管的配合实现对顽固血栓进行冲洗并抽吸，提高血栓清除效果；本发明通过在抽吸导管上设置第一球囊，在溶栓导管的溶栓冲洗腔上设置第二球囊，通过充气堵封血管，实现防止脱落血栓或细小血栓对远端血管的堵塞，避免二次堵塞，提高装置的使用安全性。
The invention discloses a thrombolysis and suction device for thrombus, comprising: a suction catheter and a thrombolysis catheter arranged in the suction catheter; the invention realizes the flushing of the stubborn thrombus and the elimination of the thrombus through the cooperation of the suction catheter and the thrombolysis catheter. Suction improves the thrombus removal effect; in the present invention, a first balloon is set on the suction catheter, and a second balloon is set on the thrombolysis flushing cavity of the thrombolysis catheter, and the blood vessels are blocked by inflation, so as to prevent falling thrombus or small thrombus. The thrombus blocks the distal blood vessels, avoids secondary blockage, and improves the safety of the device.
Description
Technical Field
The invention relates to medical equipment, in particular to a thrombus thrombolysis and suction device.
Background
Stroke (Stroke) is the name of Stroke, a disorder of cerebral blood circulation that is a sudden onset of disease, also known as a cerebrovascular accident. Stroke is mainly caused by stenosis, occlusion or rupture of the cerebral vessels and is classified into ischemic stroke (e.g., cerebral infarction, transient ischemic attack) and hemorrhagic stroke (e.g., cerebral hemorrhage and subarachnoid hemorrhage).
At present, thrombolytic therapy is still the mainstream treatment mode for ischemic stroke, and has certain limitations, mainly embodied in short treatment time window and low revascularization rate.
The treatment mode of mechanical thrombectomy has apparent advantage in the treatment effect, and the mechanical thrombectomy mode commonly used at present directly carries out the negative pressure suction for the suction catheter, with thrombus suction play blood vessel to rebuild the blood flow, nevertheless lie in serious stenosis pathological change portion distal end or the stubborn adherence of thrombus on the vascular wall when the thrombus, simple negative pressure suction embolus effect is very limited, can increase the operation risk moreover.
In addition, the thrombus is sucked by only sucking the catheter, and because of the pressure caused by suction, the remained thrombus after suction is likely to be crushed, becomes smaller thrombus and runs to the far end of the blood vessel to cause secondary blockage; the market needs a device which can wash and suck the stubborn thrombus, improve the thrombus removal effect and prevent secondary blockage, and the invention solves the problems.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide a thrombus thrombolysis and suction device, which can flush and suck stubborn thrombus, improve the thrombus clearing effect, prevent the blockage of the distal end blood vessel by fallen thrombus or fine thrombus, avoid secondary blockage and improve the use safety of the device.
In order to achieve the above object, the present invention adopts the following technical solutions:
a thrombolytic and aspiration device comprising: a suction catheter, a thrombolytic catheter disposed within the suction catheter; the suction catheter comprises: the thrombus-dissolving catheter comprises a suction catheter body, a thrombolytic catheter cavity, a suction catheter joint, a first developing piece and a first sealing assembly, wherein the thrombolytic catheter cavity is arranged in the suction catheter body and used for accommodating a thrombolytic catheter; the thrombolysis catheter includes: the thrombolysis catheter body is arranged in the thrombolysis catheter body, the thrombolysis flushing cavity is connected with the thrombolysis flushing cavity and is used for injecting an injection port of thrombolysis medicine, the second developing part is arranged at one end of the thrombolysis flushing cavity, the second sealing component is used for plugging a blood vessel, and the thrombolysis catheter joint is arranged at the other end of the thrombolysis flushing cavity.
In an embodiment of the present invention, the first sealing assembly includes: the first balloon is arranged at one end of the suction catheter body and used for blocking a blood vessel, and the first inflation cavity is connected with the first balloon and arranged in the suction catheter body.
In the thrombus thrombolysis and aspiration device, the aspiration catheter connector comprises: a thrombolytic catheter insertion port connected to the thrombolytic catheter, a suction connector, a first balloon inflation connector connected to the first inflation lumen.
In an embodiment of the present invention, the second sealing assembly includes: a second sacculus arranged at one end of the thrombolysis flushing cavity and used for blocking blood vessels, and a second inflation cavity connected with the second sacculus and arranged in the thrombolysis catheter body.
In the thrombus thrombolysis and suction device, the thrombolysis catheter connector comprises: a second balloon inflation connector connected to the second inflation cavity, and a thrombolytic injection connector.
In the thrombus thrombolysis and suction device, the first developing member is a first developing ring, and the second developing member is a second developing ring.
In the thrombus thrombolysis and suction device, the thrombolysis flushing cavity is provided with scale marks at a position close to the joint of the thrombolysis catheter.
The invention has the advantages that:
according to the invention, by thrombolysis and washing of the stubborn thrombus, compared with a device which is only used for suction, the suction effect of the stubborn thrombus is further increased, so that the application range of the suction catheter is enlarged, and the thrombus can be removed more thoroughly;
the invention is provided with the injection port for injecting thrombolytic drugs, helps the thrombolysis and can further assist in washing;
according to the invention, by arranging the first balloon and the second balloon, the blood vessel can be blocked during thrombolysis and thrombolysis, so that the blockage of the far-end blood vessel by falling thrombus or fine thrombus is prevented, secondary blockage is avoided, and the use safety is improved.
Drawings
FIG. 1 is a schematic cross-sectional view of one embodiment of the present invention;
FIG. 2 is a schematic XY cross-sectional view of one embodiment of a thrombolytic catheter of the invention;
FIG. 3 is a schematic cross-sectional view in the Z-direction of one embodiment of the thrombolytic catheter of the present invention;
FIG. 4 is a schematic XY cross-sectional view of one embodiment of an aspiration catheter of the present invention;
FIG. 5 is a schematic cross-sectional Z-direction view of one embodiment of an aspiration catheter of the present invention;
FIG. 6 is a schematic representation of the use of an embodiment of the present invention;
FIG. 7 is a schematic diagram of the operation of an embodiment of the present invention in use;
the meaning of the reference symbols in the figures:
1, 10, 11, a thrombolysis flushing cavity, 12, a second balloon, 13, a second developing ring, 14, a calibration line, 15, 16, a second balloon inflation connector, 17, a thrombolysis injection connector and 18, wherein the thrombolysis flushing cavity is formed by connecting the first balloon and the second balloon;
2, a suction catheter, 20, a suction catheter body, 21, a thrombolytic catheter cavity, 22, a first developing ring, 23, a suction cavity, 24, a first balloon, 25, a first inflation cavity, 26, a thrombolytic catheter insertion port, 27, a suction connector and 28, a first balloon inflation connector;
30 thrombus.
Detailed Description
The invention is described in detail below with reference to the figures and the embodiments.
As shown in fig. 1, a thrombolysis and aspiration device for a thrombus 30 includes: a suction catheter 2, a thrombolysis catheter disposed in the suction catheter 2.
As shown in fig. 4 and 5, the suction catheter 2 includes: the suction catheter comprises a suction catheter body 20, a thrombolytic catheter cavity 21 which is arranged in the suction catheter body 20 and accommodates the thrombolytic catheter, a suction cavity 23 which is arranged in the suction catheter body 20 and is positioned below the thrombolytic catheter cavity 21, a suction catheter joint which is arranged at one end of the suction catheter body 20, a first developing piece which is arranged at the other end of the suction catheter body 20, and a first sealing component which is used for sealing a blood vessel.
The first seal assembly includes: a first balloon 24 arranged at one end of the suction catheter body 20 and used for sealing blood vessels, and a first inflation cavity 25 connected with the first balloon 24 and arranged in the suction catheter body 20.
The suction catheter adapter comprises: a thrombolytic catheter insertion port 26 connected to the thrombolytic catheter, a suction connector 27, and a first balloon inflation connector 28 connected to the first inflation chamber 25. The first balloon inflation connector 28 is connected with the first inflation cavity 25, the first inflation cavity 25 is connected with the first balloon 24, when blood flow at the near end of the blood vessel needs to be blocked, the first balloon 24 is inflated, the blood vessel is sealed and blocked, and the tiny thrombus 30 is prevented from falling off to block other blood vessels.
As shown in fig. 2 and 3, the thrombolytic catheter is disposed in the thrombolytic catheter lumen 21, and includes: the thrombolytic catheter comprises a thrombolytic catheter body 10, a thrombolytic flushing cavity 11 arranged in the thrombolytic catheter body 10, an injection port 14 connected to the thrombolytic flushing cavity 11 and used for injecting thrombolytic drugs, a second developing part arranged at one end of the thrombolytic flushing cavity 11, a second sealing component used for sealing blood vessels, and a thrombolytic catheter joint arranged at the other end of the thrombolytic flushing cavity 11. As an example, the second developing member is a second developing ring 13.
The thrombolysis flushing cavity 11 is of a closed structure at the end close to the second developing ring 13, and the second developing ring 13 is used for confirming the end position of the thrombolysis catheter. A second balloon 12 is arranged at a position close to the second developing ring 13, so that the distal blood vessel can be blocked, and an injection port 14 is arranged at a position close to the second balloon 12; thrombolytic drugs are injected through the injection port 14 to help the thrombus 30 dissolve, which may further assist in the flushing.
The second seal assembly includes: a second balloon 12 arranged at one end of the thrombolysis flushing cavity 11 and used for sealing the blood vessel, and a second inflation cavity 18 connected with the second balloon 12 and arranged in the thrombolysis catheter body 10. The thrombolytic catheter joint is a Y-shaped Ruhr joint, and is respectively a second balloon inflation joint 16 and a thrombolytic injection joint 17. The thrombolysis flushing cavity 11 is provided with a scale mark 15 at a position close to the thrombolysis catheter joint for confirming the catheter insertion depth. When the blood flow at the proximal end of the blood vessel needs to be blocked, the second balloon inflation connector 16 is connected with the second inflation cavity 18 to inflate the second balloon 12, so that the fine thrombus 30 is prevented from falling off to block other blood vessels.
The use flow of the invention is as follows:
first, the thrombolysis and aspiration device shown in FIG. 1 is taken out of the packaging bag, and the thrombolysis aspiration lumen 11 of the thrombolysis catheter and the aspiration lumen 23 of the aspiration catheter 2 are flushed with heparin or physiological saline to remove air from the catheter.
2, a guide wire is placed in the thrombus 30 of the patient to block the blood vessel, and then the guide wire is penetrated into an suction cavity 23 of the suction catheter 2, so that the whole device is pushed to the proximal end of the thrombus 30 through the guide wire, and the position of the distal end of the catheter is determined through the first developing ring 22.
3, the first balloon 24 of the suction catheter 2 is inflated by the first balloon 24 inflation pump to block the blood flow at the proximal end of the blood vessel and prevent the fine thrombus 30 from falling off to block other blood vessels, as shown in fig. 6.
4, pushing the thrombolytic catheter through the thrombus 30, so that the injection port 14 reaches the distal end of the thrombus 30, and the pushing depth is determined by the graduation mark 15 of the proximal end of the thrombolytic catheter according to the length of the thrombus 30, as shown in fig. 7.
And 5, inflating the second balloon 12 of the thrombolytic catheter by using a second balloon 12 inflation pump to seal off the blood flow at the far end of the blood vessel and prevent the thrombus 30 from blocking the far end blood vessel.
And 6, withdrawing the guide wire from the suction catheter 2, connecting the thrombolysis injection joint 17 at the proximal end of the thrombolysis catheter with an injection pump, injecting thrombolytic drugs to complete drug flushing, and connecting the suction joint 27 at the proximal end of the suction catheter 2 with a negative pressure pump to suck the thrombus 30.
The invention can not only aspirate the thrombus 30, but also wash the stubborn thrombus 30 after drug thrombolysis, thus increasing the aspiration effect of the stubborn thrombus 30, thereby enlarging the application range of the aspiration catheter 2 and simultaneously leading the thrombus 30 to be removed more thoroughly; according to the invention, the first balloon 24 and the second balloon 12 are arranged, so that the blood vessel can be blocked, the blockage of the fallen thrombus 30 or the fine thrombus 30 to the far-end blood vessel can be prevented, the secondary blockage can be avoided, and the use safety can be improved.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It should be understood by those skilled in the art that the above embodiments do not limit the present invention in any way, and all technical solutions obtained by using equivalent alternatives or equivalent variations fall within the scope of the present invention.
Claims (7)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011364007.3A CN112545607A (en) | 2020-11-27 | 2020-11-27 | Thrombus thrombolysis and suction device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011364007.3A CN112545607A (en) | 2020-11-27 | 2020-11-27 | Thrombus thrombolysis and suction device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112545607A true CN112545607A (en) | 2021-03-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011364007.3A Pending CN112545607A (en) | 2020-11-27 | 2020-11-27 | Thrombus thrombolysis and suction device |
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| Country | Link |
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| CN (1) | CN112545607A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113208770A (en) * | 2021-04-12 | 2021-08-06 | 聚辉医疗科技(深圳)有限公司 | Conveying device |
| CN114699139A (en) * | 2022-04-21 | 2022-07-05 | 归创通桥医疗科技股份有限公司 | A thrombus removal system |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001015767A1 (en) * | 1999-08-27 | 2001-03-08 | Corazon Technologies, Inc. | Catheter devices and methods for their use in the treatment of calcified vascular occlusions |
| US20020016565A1 (en) * | 1997-03-06 | 2002-02-07 | Gholam-Reza Zadno-Azizi | Catheter system for emboli containment |
| CN108283758A (en) * | 2018-01-24 | 2018-07-17 | 张海军 | It is a kind of that there is broken, thrombolysis Biochemical analyzer function medicine eluting balloon catheter |
| CN208989037U (en) * | 2018-07-26 | 2019-06-18 | 河南亚都实业有限公司 | A vibrating catheter for removing thrombus |
| CN214595955U (en) * | 2020-11-27 | 2021-11-05 | 杭州云普医疗器械有限公司 | A thrombus thrombolysis and suction device |
-
2020
- 2020-11-27 CN CN202011364007.3A patent/CN112545607A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020016565A1 (en) * | 1997-03-06 | 2002-02-07 | Gholam-Reza Zadno-Azizi | Catheter system for emboli containment |
| WO2001015767A1 (en) * | 1999-08-27 | 2001-03-08 | Corazon Technologies, Inc. | Catheter devices and methods for their use in the treatment of calcified vascular occlusions |
| CN108283758A (en) * | 2018-01-24 | 2018-07-17 | 张海军 | It is a kind of that there is broken, thrombolysis Biochemical analyzer function medicine eluting balloon catheter |
| CN208989037U (en) * | 2018-07-26 | 2019-06-18 | 河南亚都实业有限公司 | A vibrating catheter for removing thrombus |
| CN214595955U (en) * | 2020-11-27 | 2021-11-05 | 杭州云普医疗器械有限公司 | A thrombus thrombolysis and suction device |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113208770A (en) * | 2021-04-12 | 2021-08-06 | 聚辉医疗科技(深圳)有限公司 | Conveying device |
| CN113208770B (en) * | 2021-04-12 | 2021-11-16 | 聚辉医疗科技(深圳)有限公司 | Conveyor |
| CN114699139A (en) * | 2022-04-21 | 2022-07-05 | 归创通桥医疗科技股份有限公司 | A thrombus removal system |
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Effective date of registration: 20220609 Address after: 324000 room c-324, building 1, No. 6, Kaixuan South Road, Quzhou City, Zhejiang Province Applicant after: Zhejiang Boyi Yunhua Medical Instrument Co.,Ltd. Address before: 311200 Room 301, 3 / F, building 1, No. 527, Dadi line bridge section, Heshang Town, Xiaoshan District, Hangzhou City, Zhejiang Province Applicant before: Hangzhou YUNPU Medical Equipment Co.,Ltd. |
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