CN112870500B - Intelligent storage device - Google Patents

Abstract

An intelligent admittance device comprises a voice prompt unit, a dosage monitoring unit and an information transmission unit. The processing module can judge whether the inhaled quantity reaches the effective medicine dose according to the medicine inhaled dose value collected by the dose monitoring unit arranged in the administration channel. The processing module can also selectively output different prompt instructions according to the monitoring result. The voice prompt unit sends out different medication guidance prompts according to the received instructions. The voice prompt unit at least stores three voice prompt modes, and can also send out voice prompts according to the set prompt mode actively selected by the patient, so that the patient can take medicine according to the prompt instruction. The invention can prompt the patient to take medicine on time, guide the patient to take medicine correctly, quantitatively and sufficiently, improve the medication compliance of the patient, establish high-quality big data of patient medication tracking, promote the health of the patient and provide a new practical basis for clinically promoting the health of the patient.

Description

an intelligent sensor

technical field

The present invention relates to the technical field for guiding medication, monitoring medication dose and medical information application, in particular to an intelligent calibrator.

Background technique

Chronic Obstructive Pulmonary Disease (COPD), a common preventable and treatable disease, is a group of diseases characterized by airflow limitation that is partially reversible. Morbidity and mortality are high worldwide. Globally, the prevalence of COPD ranges from 2.1% to 26.4%, due to differences in the basis of diagnosis and the completeness of data collection, with an estimated 170 million people globally affected by COPD in 2015, accounting for 3.2 million die. In 2017, approximately 544 million people worldwide suffered from chronic respiratory diseases, with a prevalence of approximately 7.1%. In the GBD (global burden disease) report, the incidence rate in high-income areas was 10.6%.

COPD is the most prevalent specific chronic respiratory disease globally, accounting for 55.1% of the global prevalence of chronic respiratory disease in men and 54.8% in women. From 1990 to 2017, the overall prevalence of COPD increased by 5.9%. According to the Harvard School of Public Health, by 2020, COPD will rise to become the third leading cause of death globally. In China, the prevalence of COPD is about 8.2%, and the number of deaths due to COPD in the country reaches 1 million each year. With the development of aging population, increasing smoking population and increasing environmental pollution, the morbidity and mortality of COPD are still on the rise. The incidence of chronic obstructive pulmonary disease is projected to rise over the next 40 years. By 2060, more than 5.4 million people could die each year from COPD and related diseases. Therefore, the demand for medical academic research on such diseases is also very urgent, and there is currently a lack of high-quality big data as research support.

At present, the treatment method for patients with chronic obstructive pulmonary disease, asthma and other diseases is mainly to relieve symptoms through long-term regular use of dry powder inhalers, and some dry powder inhalers require a calibrator for normal use. The correct use of the applicator requires professional medical staff to guide the patient, but the patient cannot give detailed instructions after leaving the hospital, and there will be failure to supply the medicine normally, the inhalation is not in place, resulting in poor control effect, and forgetting to rinse the mouth after inhalation. Inflammation and other issues.

The research literature has reported that less than 80% of patients use inhaled drugs as prescribed, 49-55% of patients do not use dry powder inhalers properly, and 70% of medical staff (from primary and secondary care providers) do not know how to use them properly the inhaler method, but 75% of medical staff are still teaching patients on a regular basis. In addition, some studies have shown that regular medication is beneficial to prolong the lifespan of patients, and the lifespan of patients is proportional to the amount of drug use.

In addition, from the analysis of the deposition rate of the drug in the lungs, the distribution of budesonide in the lungs of normal people through inhalation, the deposition rate of budesonide in the lungs was (27.7±9.5)% when inhaled rapidly, and the deposition rate of budesonide in the lungs by slow inhalation was (27.7±9.5)%. The intrapulmonary deposition rate was (14.8±3.3)%. The deposition rate of inhaled salbutamol in the lungs was (21.6±8.9)%; the deposition rate of inhaled salbutamol in the lungs of patients with airflow limitation was (19.0±8.9)%. To sum up, the accuracy and compliance of patients with inhaling medicines using the quasi-nano device is low, and the deposition rate of the drug in the lungs is limited, all of which remind us of the importance of regular and correct use of the quasi-nano device. Therefore, we carried out this study. invention.

Chinese patent CN104784051A discloses a medication tracking device and a tracking method, including a probe, a host, a plurality of buckles, a thumb ring, an LED indicator light and a connector; the connector is annularly arranged in the center of the applicator housing; the thumb handle Located on one side of the housing of the applicator, the thumb ring is glued to the housing of the applicator, a plurality of snaps are arranged on the lower end face of the host, the host is movably connected to the connector through a plurality of snaps, the host, the connector and the stand The sensor housing is coaxially arranged; one end of the probe is connected to the host, the other end of the probe is located at the edge of the sensor housing, and the end of the probe and the thumb handle are respectively located at both ends of the sensor housing; the LED indicator is set at the On the host, there is a control component in the host. In addition to tracking the medication information, the invention also has a medication reminder function. The patient can set the daily medication time. When the medication is not taken after the time it should be taken, the device will issue a sound and light reminder.

However, this application does not meet the actual needs of professional medical staff to guide the correct use of the applicator. When the patient takes medicine at home, because of the lack of detailed guidance from professional medical staff, the patient will often operate the applicator by himself. Unable to supply the medicine normally, the patient's inhalation action is not in place, the operation steps are inaccurate, the inhaled dose of the medicine is not as expected, and the oral inflammation caused by forgetting to rinse the mouth after inhalation.

In addition, on the one hand, there are differences in the understanding of those skilled in the art, and on the other hand, because the inventor has studied a large number of documents and patents when making the present invention, but the space limit does not list all the details and contents in detail, but this is by no means The present invention does not possess the features of the prior art, on the contrary, the present invention already possesses all the features of the prior art, and the applicant reserves the right to add relevant prior art to the background art.

SUMMARY OF THE INVENTION

In view of the deficiencies of the prior art, in order to improve the accuracy of the patient's medication operation and medication compliance, the present invention provides an intelligent applicator, comprising: a voice prompt unit integrated into the respiratory drug delivery device for providing Operation prompt of the respiratory drug delivery device; dose monitoring unit, which is combined with the drug delivery channel, and the sensing module is arranged on the inhalation section of the drug delivery channel, so that it can more accurately sense the inside of the pipeline of the inhalation section during the drug inhalation process The air pressure change of the device is used to measure the dose value of the inhaled drug; the information transmission unit, which is integrated on the shell of the drug delivery container, is used to store and transmit the acquired and collected monitoring data to the processing module, and the processing The module can determine whether the inhalation amount reaches the effective drug dose according to the dose value of the drug inhalation collected by the dose monitoring unit arranged in the drug delivery channel, and the processing module can also selectively output different prompt instructions according to the monitoring result, The voice prompting unit sends out different medication guidance prompts according to the received instructions; the voice prompting unit stores at least three voice prompting modes, and it can also send out voice prompts according to the set prompting mode selected by the patient, and the patient can Instructions for administering medication. The voice prompt unit enables the patient to carry out the correct medication operation without the guidance of professional medical staff, helps the patient to inhale the drug effectively, and guides the patient to follow the voice prompt step by step and perform the operation steps step by step, so that the patient can use it accurately. , and the patient can select different prompting modes according to their needs, which is convenient for the patient to select an appropriate prompting guidance and monitoring mode in the case of initial use or multiple use. In addition, the application is also provided with a dose monitoring unit and an information transmission unit. When the patient follows the voice prompt instructions to perform step-by-step operations, the use of the calibrator can be monitored. Judging whether the patient uses the applicator correctly, it can effectively monitor the patient's drug use, and give adjustment suggestions based on the judgment result, so that the patient can correctly correct himself without the guidance of professional medical staff. Using the applicator to ensure the effectiveness of medication, it can also adjust the mode of medication prompts according to the actual medication situation monitored, urging and instructing patients to more standardize medication.

According to a preferred embodiment, the voice prompting unit includes at least a first storage module, a receiving module and a first processing module, and the first processing module can collect the sound signal emitted when the sliding rod is pulled through the receiving module , the first processing module performs comparison and identification according to the sound characteristic data of the pulling sliding rod that is pre-collected by the first storage module and the sound signal collected by the receiving module, and the first processing module also sends The voice prompter sends the recognition result and controls it to send out prompting information, wherein the sound characteristic data corresponds to the sound made when the sliding rod is pulled in place.

According to a preferred embodiment, the first storage module can store various operation prompt information, and the operation prompt information corresponds to the status information, the recognition result and the response signal; the receiving module can be used for receiving trigger button, sound Status information, identification results, and response signals sent by the identifier and the proximity sensor; the first processing module can retrieve corresponding operation prompts from the first storage module according to the status information, identification results, and response signals received by the receiving module, respectively. information, the first processing module controls the voice prompter to send out a voice prompt signal according to the operation prompt information; the voice prompter is used to send out a voice prompt signal.

According to a preferred embodiment, the dose monitoring unit includes a sensing module, a second processing module, a display module and a second storage module, wherein the sensing module can sense the air pressure value inside the inhalation section and convert the air pressure value into a voltage The value is sent to the second processing module, and the second processing module converts the voltage value into the dose value of the drug inhaled by the patient, and judges whether the inhaled dose value is sufficient; the second processing module can record the time and time of drug inhalation. The number of times is displayed by the display module and stored by the second storage module; when the information transmission unit is connected with the dose monitoring unit, the drug inhalation data recorded by the second storage module can be transmitted to the medical monitoring platform for analysis Compared with interpretation, the advantage is that the medical monitoring platform set up takes the application of respiratory drug-related data to a new level, establishes high-quality big data as medical research support, provides quantitative reference standards for patients and medical workers, and promotes Research on disease treatment; also enables medical workers to understand patients' medication status and treatment effects in order to improve treatment methods and help to propose health promotion interventions.

According to a preferred embodiment, the voice prompt unit prompts several states of the respiratory drug delivery device in the form of graphics, text, sound and light, and the voice prompt unit includes a display screen, an indicator light, a buzzer, and a vibrator. The information transmission unit is signally connected with the voice prompt unit and the dose monitoring unit, and it can transmit the data information collected by the dose monitoring unit to the processing unit and/or the medical In the monitoring platform, the information transmission unit can also transmit the prompt designation fed back by the processing unit to the voice prompt unit.

According to a preferred embodiment, the information sent by the voice prompting unit, the dose monitoring unit and the information transmission unit can be stored by the processing unit to calculate the effective drug dose.

According to a preferred embodiment, the dose monitoring unit further includes a supplemental inhalation control module, and the supplemental inhalation control module is connected to the drug container; when the dose of the drug inhaled by the patient is insufficient, the supplementary inhalation control module It can remind and assist the patient to complete the secondary inhalation by means of information prompting and blocking the closing of the medicine outlet of the medicine container.

According to a preferred embodiment, the applicator further comprises an individual data management terminal, and the individual data management terminal uses the information received from the voice prompt unit, the dose monitoring unit and the information transmission unit as input information to generate individual medication data Report and provide display, individual medication data report includes single medication data and accumulated several times medication data.

According to a preferred embodiment, the individual data management terminal generates a recommended medication method according to the individual medication data report, and the recommended medication method includes a second inhalation suggestion and preparation operations before inhalation; the recommended medication method is confirmed to be adopted Afterwards, the individual data management terminal sends control instruction information to the respiratory drug delivery device, and controls the corresponding module to perform actions in accordance with the instructions. Scientifically collect and apply information on the process of inhalation and drug administration, so that the patient can standardize the drug inhalation operation according to the instructions and suggestions, and it can also assist the patient to timely follow the prompts and/or operation instructions when the effective dose of the inhaled drug is low. Directly carry out the secondary inhalation operation, so that a single course of inhalation can obtain a sufficient amount of drug dose. In addition, the prompt module is used in combination with the intelligent terminal to prompt the patient to take medicine, and at the same time, the situation of forgetting to carry or not being able to find the respiratory drug delivery device is avoided at the same time.

The present application also provides a method of using an intelligent applicator. A voice prompting unit is provided on the respiratory drug delivery device; the mouthpiece of the respiratory drug delivery device is placed close to the patient's mouth, and the voice prompting unit is respectively sent according to the trigger button. The status information, the recognition result sent by the voice recognition module, and the response signal sent by the proximity sensor send out corresponding operation prompt information.

Description of drawings

Fig. 1 is the logic module diagram of a kind of intelligent receiver of the present invention;

FIG. 2 is a schematic diagram of the structure of the smart sensor of the present invention.

List of reference signs

100: Voice prompting unit 101: First storage module 102: Receiving module

103: first processing module 104: voice prompter 200: dose monitoring unit

201: Induction module 202: Second processing module 203: Display module

204: Second storage module 205: Supplementary suction control module 300: Information transmission unit

400: Individual data management terminal 500: Respiratory drug delivery device 501: Medicine container

502: Administration Channel 600: Processing Module

Detailed ways

An applicator with medication guidance function, medication monitoring function and information transmission function, as shown in FIG. 1 , includes: a voice prompt unit 100 , a dose monitoring unit 200 and an information transmission unit 300 . When in use, the voice prompting unit 100 can give targeted guidance instructions or voice prompts according to various information or sensing signals triggered and acquired by the actual operation of the patient. In addition, whether the inhaled amount of the medicine is sufficient is monitored in real time by the dose monitoring unit 200 to determine whether the patient is using the applicator correctly. Finally, the collected medication data and various parameters during drug inhalation are transmitted to the hospital's medical monitoring platform through the information transmission unit, so that medical staff and patients can analyze and study the usage, and help medical staff to provide patients with more complete Effective medication guidance can effectively improve the effect of medication.

According to a specific embodiment, the body of the applicator is a respiratory drug delivery device 500 composed of a drug container 501 and a drug delivery channel 502 . The respiratory drug delivery device 500 is provided with a voice prompt unit 100, a dose monitoring unit 200 and an information transmission unit 300, so as to effectively instruct the patient to use the applicator correctly without being accompanied by a professional medical staff. Wherein, the voice prompting unit 100 provides prompt information of the corresponding drug inhalation operation according to the selected guidance mode, and the voice prompting unit 100 can also make targeted recommendations according to the drug conditions obtained and analyzed by the dose monitoring unit 200 and the information transmission unit 300 Operation tips. The dose monitoring unit 200 monitors and controls the output of the drug in the drug container and transmits the acquired dose value to the processing module 600 . The information transmission unit 300 is interconnected with the dose monitoring unit 200, and stores the collected information and transmits the recorded drug inhalation data to the processing module 600 for analysis and interpretation.

The voice prompting unit 100 includes a first storage module 101 , a receiving module 102 and a first processing module 103 . The first processing module 103 collects the sound signal emitted when the sliding rod is pulled through the receiving module 102, so that the first processing module 103 can collect and store the sound characteristic data in advance according to the first storage module 101 and the sound signal collected by the receiving module 102. Compare and identify. When the comparison result corresponds to the pre-collected sound feature data, that is, when the sound feature data corresponds to the sound produced when the sliding rod is pulled in place, the first processing module 103 sends the recognition result to the voice prompter 104 and controls it to emit prompt information. The first storage module 101 stores various operation prompt information, and the operation prompt information corresponds to the status information, the recognition result and the response signal. The receiving module 102 is configured to receive the status information, the recognition result and the response signal sent by the trigger button, the sound recognizer and the proximity sensor. Preferably, the voice prompt unit 100 prompts several states of the respiratory drug delivery device 500 in the form of graphics, text, sound and light, and the voice prompt unit 100 includes any one or more of a display screen, an indicator light, a buzzer, and a vibrator. combination of species. Specifically, the first processing module 103 retrieves corresponding operation prompt information from the first storage module 101 according to the status information, the identification result, and the response signal received by the receiving module 102 respectively. The first processing module 103 controls the voice prompt unit 100 to issue a voice prompt signal according to the operation prompt information. Preferably, the voice prompt unit 100 is used to send out a voice prompt signal. In addition, various types of operation prompt information stored in the first storage module 101 are issued with different voice prompts according to the different working modes of the applicator selected by the patient. Preferably, the patient can select the working mode of the nanometer in advance according to the needs. For example, a quasimeter can have the following four operating modes:

Mode 1: Brief voice prompts, allowing the patient to quickly understand the use specifications of the applicator, so that the patient can quickly become familiar with the normative operation process before use;

Mode 2: Teaching and guidance mode, voice prompts are given step by step, actions are confirmed step by step, remote intervention is necessary, and the medical staff can directly guide the patient through voice or video medication operation through the individual data management terminal based on the smartphone in the patient's hand. , this mode helps patients to make accurate drug inhalation operations according to detailed voice prompts without the on-site guidance of professional medical staff, and can also use the collected drug dosage monitoring data and various The operation data collected by the induction sensing unit is analyzed and interpreted, so as to help the patient to correct the wrong medication operation through targeted voice guidance;

Mode 3: silent monitoring mode, running in the background, monitoring the usage, and regularly feeding back the medication status to the doctor. It is only used as a monitoring of medication status, which is convenient for data recording of the patient's usage and dosage within a certain period, helping Doctors make accurate and effective medication guidance for patients;

Mode 4: Replenishment reminder and guidance. When the patient's drug inhalation volume calculated by the processing module is lower than the standard unit dose, it will prompt the patient to perform a second supplementary inhalation operation immediately according to the pre-made range of the actual inhalation volume, and give it step by step. Voice prompt, step by step to confirm the action.

Among them, when the inhaled dose of the patient is lower than the standard unit dose and higher than the minimum effective dose, the patient can be prompted to perform a second inhalation, and the patient can re-inhale according to the personal situation according to the guidance or complete the corresponding second confirmation. Afterwards, the off switch of the sensor can be turned off directly.

When the inhaled dose of the patient is lower than the minimum effective dose, the shut-off switch of the calibrator is restricted by the limited structure, and the patient needs to immediately complete the secondary instruction according to the guiding instruction and make the total inhalation amount reach the minimum effective inhalation dose. The off switch of the nanometer can be turned off according to the demand. The dose monitoring unit 200 includes a sensing module 201 , a second processing module 202 , a display module 203 and a second storage module 204 . The sensing module 201 can sense the air pressure value inside the inhalation section, convert the air pressure value into a voltage value and transmit it to the second processing module 202, and then the second processing module 202 converts the voltage value into the dose value of the inhaled medicine by the patient, and Determine if the inhaled dose is sufficient. The second processing module 202 can record the time and times of inhalation of the medicine, and display it through the display module 203 , and store it through the second storage module 204 . When the information transmission unit 300 is connected to the dose monitoring unit 200, the drug inhalation data recorded by the second storage module 204 can be transmitted to the medical monitoring platform for aggregate storage. Preferably, the medical monitoring platform can be a hospital platform, a department platform or other independently established server platform, and can also be a data processing and storage platform that can be connected with an existing medical big data platform. In addition, the information transmission unit 300 can also transmit the collected data information to the processing module 600, which is convenient for the processing module 600 to analyze and interpret the collected data, and to determine the effective dose of the actual inhaled medicine to obtain the effective inhalation dose. Occupy the standard unit dose of how much. The processing module 600 triggers the prompting instruction and prompting mode corresponding to the threshold range according to the obtained determination of the actual effective inhaled drug dose.

Preferably, the dose monitoring unit 200 further includes a supplemental inhalation control module 205 . The supplemental suction control module 205 is connected with the medicine container 501 . In the case that the dose of the drug inhaled by the patient in a single time is insufficient, the supplementary inhalation control module 205 can remind and assist the patient to complete the secondary supplementary inhalation by means of a message prompt and a manner of preventing the closure of the drug outlet of the drug container. The supplemental inhalation control module 205 can be interconnected with the switch component of the calibrator, and can issue supplemental inhalation prompts and limit the blocking of the switch component according to the threshold range of the actual drug inhalation amount. When the actual inhalation volume is lower than the effective inhalation volume, the patient needs to perform a second inhalation operation according to the guidance instructions and reach the effective inhalation standard, and then can adjust the limit unit according to personal choice and then close the applicator. Complete a complete and effective suction treatment.

Preferably, a prompt module corresponding to the supplemental suction control module 205 is provided on the surface of the housing of the calibrator. Further preferably, the prompting module may be an indicator light that can be signally connected to the inhalation control module 205, and the indicator light can send out different prompting signals according to the collected data of the actual inhaled dose of the medicine. For example, when the inhaled dose of the patient's drug is lower than the minimum effective drug dose, the indicator light is displayed in orange, thereby reminding the patient that a second re-inhalation treatment is necessary, so that the drug inhalation treatment can have a therapeutic effect. When the patient's drug inhalation amount is higher than the minimum effective drug dose and lower than the standard unit dose, the indicator light will be blue, so as to suggest the patient to perform a second re-inhalation treatment, so that the drug inhalation treatment can play a better role the therapeutic effect. However, in this case, the patient can also refuse the second inhalation according to the actual needs of the individual, but it is necessary to manually adjust the limit result connected with the switch so that the applicator can be closed smoothly.

Preferably, the information transmission unit 300 collects information such as dose changes and dosages of the drug in any or several stages of storage, release, and ingestion, and transmits the collected airflow velocity, drug particle density per unit volume of gas, etc. , inhalation duration, total amount of drug administration, residual drug amount in drug delivery channel, number of drug release switches, trigger time of drug release switch, airflow pressure difference, etc. The combination of one or more is transmitted to the medical monitoring platform for data analysis and calculation , to help the patient understand the actual usage status and the drug remaining in the device. Wherein, the remaining amount of the medicine may be the difference between the standard unit medicine dose and the effective inhalation medicine dose after a single inhalation, and this part of the residual medicine is mainly contained in the cavity and channel of the quasi-nine. The specific data of this part of the residual dose can be obtained by subtracting the actual monitored and calculated actual inhalation dose from a standard unit dose, so as to facilitate the effective control of the residual dose and judge whether it is necessary or not according to the residual dose. Perform a secondary suction operation.

Preferably, the applicator further includes an individual data management terminal 400 . The individual data management terminal 400 uses the information received from the voice prompt unit 100, the dose monitoring unit 200 and the information transmission unit 300 as input information, generates an individual medication data report and provides a display, and the individual medication data report includes the single medication data and the cumulative number of times. Medication data. The individual data management terminal 400 generates a recommended medication method according to the individual medication data report. The recommended medication method includes suggestions for re-inhalation and preparation operations before medication, etc. After the recommended medication method is confirmed and adopted, the individual data management terminal 400 sends control instruction information to the respiratory drug delivery device 500, and controls the corresponding module to perform actions in accordance with the instruction . By standardizing the drug inhalation operation, it can assist the patient to directly perform the secondary inhalation operation according to the prompt and/or operation instruction when the actual effective dose of the inhaled drug is low, so that the drug inhalation operation of a single course of treatment can ensure that the patient obtains Adequate drug dose.

Example 1

The invention discloses a quasi-nano device with a medication guidance function. Before the patient uses the applicator of the present invention, by pressing the trigger button, the voice prompt unit 100 can send out prompt information for the corresponding inhalation operation, such as: "Hold the applicator, put the thumb on the thumb, and turn the applicator. to expose the nozzle and move the slide lever into place". When the voice prompting unit 100 recognizes the sound made when the sliding rod is pulled in place through the sound recognizer in the receiving module 102, the inhalation step is entered, and the voice prompting unit 104 prompts corresponding operation prompt information, such as "Move the applicator to the correct position. Open your mouth 20 cm away, exhale forcefully, empty your lungs, and put the mouthpiece into your mouth." When the patient puts the mouthpiece into the mouth, it enters the drug inhalation process, the proximity sensor of the receiving module 102 generates a response signal, and the voice prompter 104 obtains the sent response signal, and sends out corresponding operation prompt information, such as "inhale hard". Next, enter the breath-holding drug precipitation link, the proximity sensor of the receiving module 102 generates a response signal, and the voice prompter 104 obtains the sent response signal, and sends out corresponding operation prompt information, such as "close the applicator, please hold your breath and wait for the voice Count down 10 seconds, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1... Slowly and normally exhale". After the patient has finished inhaling the medicine, the mouthpiece is taken out of the mouth, the proximity sensor of the receiving module 102 no longer generates a response signal, and the voice prompter 104 cannot obtain the response signal, and enters the aftermath link. device, gargle" operation prompt message.

Preferably, the trigger button of the smart applicator is set to be signal-connected to the power supply device, and the power supply device supplies power according to the induction signal sent by the trigger button. The power supply device is provided with a power supply, which supplies power to the voice recognizer, the proximity sensor and the prompter respectively through the control switch circuit. The control switch circuit is provided with an NPN triode and a PNP triode, and the base of the PNP triode is connected to the power supply through the protection resistor R1. For the provided signal source, the emitter is connected to the power supply, and the collector is connected to the power terminals of the voice recognizer, proximity sensor and prompter. The collector of the NPN triode is connected to the common terminal of the protection resistor R1 and the signal source, the emitter is grounded, and the base is connected to the output terminal of the proximity switch sensor through the current limiting resistor R2. When the trigger button is turned off, the NPN transistor is turned on, the base of the PNP transistor is short-circuited without current, the PNP transistor is disconnected, and the power supply device does not supply power to the voice recognizer, proximity sensor and prompter. When the trigger button is turned on, the NPN transistor is disconnected, the base current of the PNP transistor is input, the PNP transistor is turned on, and the power supply device supplies power to the voice recognizer, the proximity sensor and the prompter.

The voice prompting unit 100 includes a first storage module 101 , a receiving module 102 , a first processing module 103 and a voice prompter 104 . The first processing module 103 collects the sound signal emitted when the sliding rod of the applicator is pulled through the sound sensor of the receiving module 102 . The first processing module 103 identifies the sound signal according to the sound feature data stored in the first storage module 101, and sends the identification result to the prompter, and the sound feature data corresponds to the sound when the sliding rod is pulled in place. The voice prompting unit 100 obtains the medicine quantity information by counting the number of times the sound recognizer recognizes the sound when the sliding rod is pulled in place. The medicine quantity information can be stored in the first storage module 101, and the first storage module 101 can also use the data. Transmission to the medical monitoring platform.

Preferably, the sound sensor of the first processing module 103 adopts the sound recognition module of the existing TZ-2KA noise sensor, collects the sound signal through the sound sensor, and uses the existing sound processing technology to process the collected sound signal to obtain the sound data, and compare the sound data with the sound feature data stored in the first storage module 101, and confirm whether the collected sound signal is the sound made when the sliding rod is pulled in place, if not, it will not be fed back to the prompter At this time, the prompter will issue a prompt message that the pull is not in place at a certain time interval until the processing module feeds back the recognition result to the prompter.

The proximity sensor is a pyroelectric sensor. The proximity sensor is set to expose the mouthpiece of the applicator. When the patient puts the mouthpiece into the mouth, the proximity sensor senses the temperature of the human mouth and generates a response signal until the patient takes the mouthpiece out of the mouth.

Preferably, the prompter is provided with: a receiving module for receiving status information, recognition results and response signals sent by the trigger button, the sound recognizer and the proximity sensor; a storage module for storing various operation prompt information, the operation prompt information Corresponding to the status information, recognition results and response signals; the speaker is used to send out a voice prompt signal; the control module is used to retrieve the corresponding operation from the storage module according to the status information, recognition results and response signals received by the receiving module respectively prompt information, the control module controls the speaker to send out a voice prompt signal according to the operation prompt information.

Specifically, the receiving module is provided with interface circuits which are respectively matched with the trigger button, the proximity sensor and the voice recognizer. In this embodiment, the interface circuits are all selected from the existing interface circuits, and the specific interfaces will not be repeated. The receiving module communicates with the trigger button, the proximity sensor and the sound recognizer respectively through the interface circuit, so that it is convenient to obtain the status information, recognition results and response signals sent by the trigger button, the proximity sensor and the sound recognizer. , the information is sent to the control module, the control module determines the operation link according to the status information, the recognition result and the response signal, and retrieves the corresponding operation prompt information according to the operation link, and the control module controls the speaker to emit the corresponding voice through the existing audio control circuit.

Example 2

The present invention also discloses an applicator with a drug monitoring function, which includes a respiratory drug delivery device 500 and a dose monitoring unit 200 . The respiratory drug delivery device 500 includes at least a drug container 501 and a drug delivery channel 502, wherein the side surface of the respiratory drug delivery device 500 is sequentially connected with the drug supply nozzle, inhalation section, sliding rod and sliding cover of the drug delivery channel 502. The dose monitoring unit 200 is detachably provided on the surface of the applicator body. The dose monitoring unit 200 includes a sensing module 201 , a second processing module 202 , a display module 203 and a second storage module 204 . The sensing module 201 can sense the air pressure value inside the suction section, and convert the air pressure value into a voltage value and transmit it to the second processing module 202 . The second processing module 202 can convert the voltage value into the dose value of the drug inhaled by the patient, and determine whether the inhaled dose value is sufficient, wherein the corresponding data of the voltage value and the dose value are stored in the second storage module 204 . The dose monitoring unit 200 also includes a supplemental suction control module 205 . The supplemental suction control module 205 is connected to the drug outlet of the drug container 501, and the supplemental suction control module 205 controls the single release of the drug in the quasi-narrow by controlling the amount of the drug output from the drug outlet of the drug container 501 at a time. dose. The second storage module 204 can also transmit the data to the medical monitoring platform.

Preferably, although there are various standard doses of medicament storage foil strips, according to the setting of the actual medicament effective standard, whether the actual inhalation amount can achieve an effective therapeutic effect can be used as the judgment standard. According to the existing research and statistics in this field, it can be known that more than 75% of the patients who use the quasi-nest can not complete effective drug inhalation. The currently routinely defined effective inhalation dose of the drug is more than 80% of the standard unit dose to be considered as effective inhalation therapy. For example, for stable patients, a standard charge of chaff for daily use contains 250 micrograms of drug per foil unit. Therefore, only when the patient can inhale more than 200 micrograms of the drug into the body during the inhalation operation can it be determined that the effective drug inhalation treatment has been completed. Therefore, it is required that the dose value converted from the data sensed by the sensing module of the dose monitoring unit 200 can be greater than 200 micrograms. Only by correlating the drug inhalation dose value of the patient's actual drug inhalation treatment process with the prompt mode, can the patient be effectively supervised and guided to more accurately use the quasi-drug and complete the drug inhalation treatment operation. Preferably, according to the ratio between the actual drug inhalation amount and the standard unit drug dose, the threshold range of the actually monitored drug inhalation amount and the prompt instruction mode can be correlated as follows:

1. When the previous single actual inhalation dose of the drug is lower than 80% of the standard unit dose, the device is equipped with an indicator light reminder device, such as "voice reminder: lower than unit dose; device surface visualization: orange light on", It is recommended that patients use the "Teaching and Guidance Mode (Mode 2)" of the applicator to facilitate patients to quickly regulate their own incorrect drug inhalation operations, and to promote better drug inhalation therapy for patients;

2. When the previous single actual inhalation volume of the drug is lower than 100% of the standard unit dose and higher than 80% of the standard unit dose, the device is equipped with an indicator light reminder device, such as "Voice reminder: approaching the unit dose; Device surface visualization: blue light is on", recommending the patient to use the "brief voice prompt mode (mode 1)" of the applicator, which can guide the operation steps for patients with certain good operating habits, so that patients can better Follow the prompts to complete the drug inhalation treatment;

3. When the previous single actual inhalation amount of the drug is equal to the standard unit dose, the device is equipped with an indicator light reminder device, such as "Voice reminder: the unit dose is reached, it's great!; The surface of the device is visualized: the green light is on", It is recommended that the patient use the "silent monitoring mode (mode 3)", which only monitors the actual use of the patient, and does not provide voice prompts for the patient's drug inhalation operation;

4. When the dose of medicine inhaled by the patient using the applicator does not reach the standard unit dose, the device is equipped with an indicator light reminder device, such as "Voice reminder: lower than the unit dose, the inhaled dose is insufficient, and additional inhalation is required!"; The surface of the device is visualized: the red light is on", the present invention can also trigger the "inhalation prompt and guidance (mode 4)", which can issue different indicator lights according to the actual inhalation amount above or below 80% of the standard unit dose. .

Among them, when the actual inhalation volume is higher than 80% of the standard unit dose, the supplemental inhalation control module will advise the patient to take a second inhalation by means of a prompt light that lights up yellow. At this time, the patient can choose to accept the second inhalation according to their needs. The medicine guides or releases the restriction of the shut-off switch of the aligner with the limiting structure, and directly closes the aligner. Preferably, since the inhalation difficulty may increase when the residual drug dose is small, in order to better inhale the residual drug, the voice prompt for drug inhalation in Mode 4 can be set separately, and the step-by-step voice guidance prompts Instruct the patient to intensify the inhalation of the drug, so that the residual drug can better enter the human body.

When the actual inhalation volume is lower than 80% of the standard unit dose, the patient will be forced to perform a second inhalation operation. The patient is instructed to aspirate the residual medicine that is greater than 20% of the standard unit dosage in the applicator without closing the applicator. In this case, the shut-off switch of the applicator is locked, and the patient can only choose to close the applicator through a second inhalation operation, so that the residual drug dose in the applicator is less than 20% of the standard unit dose. .

Example 3

The invention also discloses an accelerometer with an information transmission function. The applicator includes a respiratory drug delivery device 500 , an information transmission unit 300 and an individual data management terminal 400 . As shown in FIG. 2, the respiratory drug delivery device 500 includes a drug container 501, a drug delivery channel 502 and a drug release switch, wherein the drug release switch is used to trigger the release of the drug, and the drug delivery channel can atomize the drug when the drug is used. form ejection. Preferably, the drug delivery channel includes a release section, an inhalation section and a drug supply nozzle, wherein the release section is used to connect the drug container 501, one end of the inhalation section is connected to an end of the release section away from the drug container 501, and the other end of the inhalation section is connected to the drug container 501. A mouthpiece for supplying medicines that communicates with the patient's airway. The information transmission unit 300 includes a combination of one or more of a micro pressure sensor, a micro flow rate sensor, a micro flow sensor, and a micro particle concentration sensor, so that it can collect the drug at any stage or several of the storage, release, and intake stages. information about the stage. The information transmission unit 300 can provide information about the airflow velocity in the respiratory drug delivery device 500, the density of drug particles per unit volume of gas, the duration of inhalation, the total amount of drug administered, the residual drug volume in the drug delivery channel, the number of drug release switches, and the number of drug release switches during the operation of the patient. Data such as release switch trigger time and airflow pressure difference are collected.

Preferably, the individual data management terminal 400 uses a smartphone to install a dedicated APP for terminal control. The individual data management terminal 400 takes the information received from the respiratory drug delivery device 500 as input information, generates an individual medication data report and provides a display. The individual medication data report includes single medication data and accumulated several times medication data. Preferably, the input information also includes living habits, previous pulmonary function test results, environmental factors, and the like. The environmental factors can also be collected through the environmental information collection module provided on the respiratory drug delivery device or collected from the network through the individual data management terminal 400 . Through the actual acquisition and recording of input information such as environmental factors and living habits, it is possible to effectively determine whether the patient smokes or passively inhales second-hand smoke during the treatment process, as well as external factors such as environmental PM2. The influence of the spring and summer seasons on the disease outcome, whether there are smokers in the surrounding environment of the patients in the small environment, etc.) are analyzed and determined, so that the medical staff can better guide the patients to take effective drug treatment. Preferably, the input information further includes preset information of the respiratory drug delivery device, such as drug type, drug volume, and the like. By storing and recording the information on the types of medicines and standard medicines used by the patient for a long time, it is convenient for different medical staff to understand the past medical history of the patient and make judgments on the follow-up treatment. The preset information of the respiratory drug delivery device is stored in the storage unit of the individual data management terminal 400 or collected from the network, and active input collection can also be performed through the input unit of the individual data management terminal 400 . The personal physiological health data is collected through the input module of the personal data management terminal 400 or collected from the network through the personal data management terminal 400 . The individual data management terminal 400 is also used to send control instruction information to each unit on the respiratory drug delivery device 500 . The individual data management terminal 400 sends control instruction information to the respiratory drug delivery device according to the preset or selected medication mode, controls the corresponding unit module to perform actions in accordance with the instruction, and controls the voice prompting unit 100 to remind the patient in the form of sound and light when the medication should be administered. The patient can be reminded in the form of sound and light through the individual data management terminal 400 .

The medical monitoring platform, the medical monitoring platform conducts data interaction with several individual data management terminals 400 through a wireless network; the medical monitoring platform receives individual medication data reports sent by several individual data management terminals 400, and processes, analyzes and displays the data. Through the medical monitoring platform, the data of people who use specific drugs can be collected, and by combining personal physiological data, medical record data, environmental data, medication data and other statistical analysis, long-term research on the therapeutic effect of specific drugs on specific diseases can be carried out, and the formation of An objective and detailed database, which in turn promotes all kinds of academic research and promotes the progress of medical science. Individual patients, hospitals and researchers can obtain and apply data from the medical monitoring platform through appropriate channels. For example, individual patients can know the improvement of health control and disease development of their own diseases through the treatment of this type of drugs through the medical monitoring platform, and guide their scientific research. Medication, better communication between doctors and patients, and work together to promote the health of patients. Hospitals and researchers can improve and optimize treatment methods and develop new drugs through medical monitoring platform data. In addition, it also includes a medical monitoring platform. The medical monitoring platform performs data interaction with the individual data management terminal 400 through a wireless network; the medical monitoring platform receives individual medication data reports sent by several individual data management terminals 400, and processes, analyzes, Display to monitor patient medication status and treatment effect. The medical monitoring platform is used to input personal physiological health data and push the data to the corresponding personal data management terminal 400 . The medical monitoring platform conducts data interaction with the medical monitoring platform through the wireless network. The medical monitoring platform can establish a bridge between medical staff and patients, and realize the exchange of information on medication status and treatment effect at any time.

It should be noted that the above-mentioned specific embodiments are exemplary, and those skilled in the art can come up with various solutions inspired by the disclosure of the present invention, and these solutions also belong to the disclosure scope of the present invention and fall within the scope of the present invention. within the scope of protection of the invention. It should be understood by those skilled in the art that the description of the present invention and the accompanying drawings are illustrative rather than limiting to the claims. The protection scope of the present invention is defined by the claims and their equivalents.

Claims (7)

1. An intelligent applicator, comprising: A voice prompt unit (100), integrated into the respiratory drug delivery device (500), for providing operation prompts for the respiratory drug delivery device (500), The dose monitoring unit (200), combined with the drug delivery channel (502), includes being arranged on the inhalation section of the drug delivery channel (502), and senses the change in air pressure inside the pipeline of the inhalation section during the drug inhalation process, and uses a sensor module that measures the dose of the inhaled drug, and An information transmission unit (300), integrated on the housing of the medicine container (501), is used for storing and transmitting the acquired and collected monitoring data to the processing module (600), characterized in that, The processing module (600) can determine whether the inhaled dose reaches an effective dose of the drug according to the dose value of the inhaled drug collected by the dose monitoring unit (200) disposed in the drug delivery channel (502), and the processing module (600) ) can also selectively output different prompting instructions according to the monitoring results, so that the voice prompting unit (100) issues different medication guidance prompts according to the received instructions; The voice prompting unit (100) stores at least three voice prompting modes, and can issue a voice prompting according to a set prompting mode actively selected by the patient, so that the patient can perform a medication operation according to the prompting instruction; The voice prompting unit (100) at least includes a first storage module (101), a receiving module (102) and a first processing module (103), and the receiving module (102) collects the sound signal emitted when the sliding rod is pulled, The first processing module (103) can compare and identify the sound characteristic data collected in advance by the first storage module (101) and the sound signal collected by the receiving module (102) to obtain a recognition result, and the The first processing module (103) also sends the recognition result to the voice prompter (104) and controls it to send out prompt information, wherein the sound feature data corresponds to the sound emitted when the sliding rod is pulled in place; The dose monitoring unit (200) further includes a supplemental inhalation control module (205), the supplemental inhalation control module (205) is connected with the medicine container (501); in the case that the dose of the medicine inhaled by the patient is insufficient, the The supplemental inhalation control module (205) can remind and assist the patient to complete the second supplementary inhalation by means of information prompting and blocking the closure of the drug outlet of the drug container (501); The applicator further comprises an individual data management terminal (400), the individual data management terminal (400) receives information from the voice prompt unit (100), the dose monitoring unit (200) and the information transmission unit (300) as Input information, generate individual medication data report and provide display, individual medication data report includes single medication data and accumulated several times medication data; The individual data management terminal (400) uses information received from the respiratory drug delivery device (500) as input information, and the input information includes living habits, previous pulmonary function test results, environmental factors, and preset information of the respiratory drug delivery device, wherein the environment The factors are collected through the environmental information collection module provided on the respiratory drug delivery device or collected from the network through the individual data management terminal (400). 2 . The intelligent receiver according to claim 1 , wherein the first storage module ( 101 ) stores operation prompt information, and the operation prompt information corresponds to the status information, the recognition result and the response signal; 2 . The receiving module (102) can be used to receive the status information, the recognition result and the response signal sent by the trigger button, the sound recognizer and the proximity sensor; The first processing module (103) can respectively retrieve corresponding operation prompt information from the first storage module (101) according to the status information, the identification result and the response signal received by the receiving module (102), the first processing The module (103) controls the voice prompter (104) to issue a voice prompt signal according to the operation prompt information; The voice prompter (104) is used to issue a voice prompt signal. 3. The intelligent applicator according to claim 2, wherein the dose monitoring unit (200) comprises a sensing module (201), a second processing module (202), a display module (203) and a second storage module A module (204), wherein the sensing module (201) can sense the air pressure value inside the suction section, convert the air pressure value into a voltage value and transmit it to the second processing module (202), and then the second processing module (202) will The voltage value is converted into the dose value of the drug inhaled by the patient, and it is judged whether the inhaled dose value is sufficient; The second processing module (202) can record the time and the number of times of drug inhalation, and display it through the display module (203), and simultaneously store it through the second storage module (204); When the information transmission unit (300) is connected to the dose monitoring unit (200), the information transmission unit (300) transmits the drug inhalation data recorded by the second storage module (204) to the medical monitoring platform for aggregate storage. 4. The intelligent applicator according to claim 3, wherein the voice prompting unit (100) prompts several states of the respiratory drug delivery device (500) in the form of graphics, text, sound and light, and the voice prompts The prompting unit (100) includes any one or a combination of any one of a display screen, an indicator light, a buzzer, and a vibrator; The information transmission unit (300) is in signal connection with the voice prompt unit (100) and the dose monitoring unit (200), and is capable of transmitting the data information collected by the dose monitoring unit (200) to the processing module (600) ) and/or a medical monitoring platform, the information transmission unit (300) can also transmit the prompt designation fed back by the processing module (600) to the voice prompt unit (100). 5. The intelligent applicator according to claim 4, wherein the information sent by the voice prompt unit (100), the dose monitoring unit (200) and the information transmission unit (300) can be sent by the processing module ( 600) for storage and calculation of effective drug doses. 6 . The intelligent applicator according to claim 1 , wherein the individual data management terminal ( 400 ) generates a recommended medication method according to the individual medication data report, and the recommended medication method includes a suggestion for a second inhalation and a medication recommendation method. 7 . Preparation operation before inhalation; after the recommended medication method is confirmed and adopted, the individual data management terminal (400) sends control instruction information to the respiratory drug delivery device (500), and controls the corresponding module to perform actions in accordance with the instruction. 7. A method of using the intelligent quasi-sensor according to one of claims 1 to 6, characterized in that, A voice prompt unit (100) is provided on the respiratory drug delivery device (500); The mouthpiece of the respiratory drug delivery device (500) is brought close to the patient's mouth, and the voice prompting unit (100) issues a corresponding operation according to the status information sent by the trigger button, the recognition result sent by the voice recognition module, and the response signal sent by the proximity sensor prompt information.

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