CN218250319U

CN218250319U - Portable porous pipettor

Info

Publication number: CN218250319U
Application number: CN202222752214.7U
Authority: CN
Inventors: 季翔; 冯爱华; 王文博
Original assignee: Liling Biopharmaceutical Suzhou Co ltd
Current assignee: Liling Biopharmaceutical Suzhou Co ltd
Priority date: 2022-10-19
Filing date: 2022-10-19
Publication date: 2023-01-10
Anticipated expiration: 2032-10-19

Abstract

The utility model relates to a portable porous pipettor, which comprises a housin, a plurality of parts of absorbing, imbibition mechanism, interval adjustment mechanism is connected with a plurality of parts of absorbing, interval adjustment mechanism includes the actuating lever, threaded rod and drive assembly, the actuating lever, the threaded rod all can set up around self axial lead rotation ground, it makes the actuating lever rotate and drives the threaded rod rotation to be connected through the drive assembly transmission between actuating lever one end and the threaded rod, the extending direction of threaded rod is unanimous with a plurality of array orientation of absorbing the part, the screw thread that lies in the actuating lever both sides on the threaded rod revolves to opposite, threaded connection between absorption part and the threaded rod. The utility model has stronger applicability and convenient operation in the actual biochemical experiment; the standard spacing can be quickly positioned; the charging operation is not needed, the use of precise components is reduced, the complex program setting operation is not needed, the cost is relatively low, and the matched consumable materials are not needed to be developed; the durability is strong, and the maintenance is easy.

Description

Portable porous pipettor

Technical Field

The utility model relates to a pipettor technical field especially relates to a portable porous pipettor.

Background

The porous pipettor is one of the common devices in biological or chemical laboratories, is mainly used for quantitatively measuring trace liquid in the experimental process, and has multiple specifications for liquid absorption range selection in the market.

At present, a plurality of research laboratories engaged in biomedicine use porous pipettors, and because the distance between each liquid suction channel is fixed, only standardized centrifuge tubes can be used in the liquid suction process, the space distance cannot be adjusted at will, and the requirements in the biomedicine research cannot be well met. Although a microporous pipettor with an electrically adjustable interval is newly developed in the market, the pipettor has the defects of short charging time, long charging time, complex program setting, high price, high daily maintenance program responsibility, high maintenance cost and the like.

See patent publication No. CN214514675U, which discloses an interval-adjustable multichannel rower, which increases or decreases the portion of an adjusting screw passing through a threaded hole and extending into a housing by rotating the adjusting screw, the longer the portion of the adjusting screw extending into the housing, the farther away from the threaded hole a first slider connected with the adjusting screw through a connecting groove, the larger the degree of deformation of the first spring due to extrusion, the smaller the interval between pipettors, the shorter the portion of the adjusting screw extending into the housing, the closer the first slider connected with the adjusting screw through the connecting groove is to the threaded hole, the smaller the degree of deformation of the first spring due to extrusion, and the larger the interval between the pipettors. However, pipettors located on two sides need to be adjusted through two adjusting screws respectively, so that on one hand, the pipettors are relatively troublesome to adjust, and on the other hand, the pipettors on two sides are difficult to ensure that the intervals between the pipettors on two sides are adjusted to be equal.

Disclosure of Invention

The utility model aims at providing a portable porous pipettor, especially a portable porous pipettor of manually adjustable hole interval.

In order to achieve the above purpose, the utility model adopts the technical scheme that:

a portable multi-well pipette comprising:

a housing;

a plurality of suction members arranged along a line;

the liquid suction mechanism is connected with the plurality of suction components and is used for controlling the plurality of suction components to suck liquid or discharge liquid;

spacing adjustment mechanism, spacing adjustment mechanism with a plurality of the part of absorbing connect for adjust adjacent two the part of absorbing between the interval, spacing adjustment mechanism include actuating lever, threaded rod and drive assembly, actuating lever, threaded rod all can set up around self axial lead with rotating, actuating lever one end with the threaded rod between pass through the drive assembly transmission connect and make the actuating lever rotate the drive the threaded rod rotate, the extending direction of threaded rod with a plurality of the array orientation of the part of absorbing unanimous, and the threaded rod on lie in the screw thread of actuating lever both sides revolve to opposite, the part of absorbing with threaded rod between threaded rod threaded connection.

Preferably, the threaded rod and the transmission assembly are arranged in the shell, and the other end of the driving rod extends out of the top of the shell for operation; the distance adjusting mechanism further comprises an adjusting operation piece and an adjusting locking piece, wherein the adjusting operation piece is connected to the position, extending out of the shell, of the driving rod and is used for operating the driving rod to rotate; the adjusting and locking piece is connected with the driving rod or the adjusting and operating piece and used for locking the driving rod in a rotating mode.

Preferably, in the above technical solution, the distance adjusting mechanism further includes a distance digital display module for displaying the distance between the suction members.

Preferably, the distance between the sucking parts is adjusted within the range of-10.0 to 10.0 mm.

Above-mentioned technical scheme is preferred, actuating lever, threaded rod be light-duty stainless steel.

Preferably, the suction component comprises a suction head connector and a suction pipe, and the upper part of the suction head connector is positioned in the shell and is connected with the liquid suction mechanism and the spacing adjusting mechanism; the lower part of the sucker connecting piece extends out of the bottom of the shell, and the sucker is detachably connected to the lower part of the sucker connecting piece.

Further preferably, the suction part further comprises a transmission block connected to the suction head connector, and the threaded rod penetrates through the transmission block and is in threaded fit with the transmission block.

Further preferably, the suction head connecting piece is conical with the diameter gradually decreasing from top to bottom.

Further preferably, the suction head connecting piece and the transmission block are made of light stainless steel.

Above-mentioned technical scheme is preferred, imbibition mechanism including pump the action bars, pump the subassembly and the flexonics pipe, pump the subassembly, the flexonics pipe sets up the casing in, pump the one end of action bars and pump the subassembly and be connected and be used for the drive the action of pumping the subassembly, the other end of pumping the action bars stretch out the casing top for the operation, pump the subassembly pass through the flexonics pipe with the part of absorbing connect.

Further preferably, the flexible connecting tube is made of plastic, such as a capillary tube.

Preferably, in the above technical solution, the liquid suction mechanism includes a digital volume display module for displaying the liquid suction amount of the suction member.

Preferably, in the above technical solution, the liquid absorption range of the absorption member is 0.5 to 10.00uL.

Because of the application of the technical scheme, compared with the prior art, the utility model has the advantages of it is following:

1. the liquid suction mechanism and the spacing adjusting structure are independent from each other and do not influence each other, so that the liquid suction mechanism has stronger applicability and convenient operation in actual biochemical experiments;

2. the standard distance can be quickly positioned, and the requirements of the conventional experimental work environment in daily work and the actual requirements in medical scientific research are met;

3. the charging operation is not needed, the use of precise components is reduced, the complex program setting operation is not needed, the cost is relatively low, the device can be matched with a suction head with a 10uL range which is generally used in the market, and matched consumables are not needed to be developed;

4. strong durability, easy maintenance and convenient use.

Drawings

Fig. 1 is an external schematic view of a multi-well pipette in this example;

fig. 2 is an internal schematic view of the multi-hole pipette of the present embodiment;

fig. 3 is a schematic diagram of the engagement of the threaded rod and the transmission block in this embodiment.

In the above drawings:

1. a housing; 10. a finger hook;

20. a suction head connecting piece; 21. a straw; 22. a transmission block;

30. a drive rod; 31. a threaded rod; 32. an adjustment operator; 33. adjusting the locking piece; 34. a distance digital display module;

40. a pump pumping lever; 400. a pressure head; 41. a flexible connecting pipe; 42. a pumping assembly; 43. and a capacity digital display module.

Detailed Description

The technical solutions of the present invention will be described more clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

A portable multi-hole pipette as shown in fig. 1 and 2 includes a housing 1, a plurality of suction members, a spacing adjustment mechanism, and a suction mechanism. The respective components and mechanisms will be described in detail below.

The suction component, the interval adjusting mechanism and the liquid suction mechanism are all arranged on the shell 1 or in the shell 1, and the finger hook 10 is arranged at the top of the shell 1, so that the liquid suction device can be conveniently taken and operated. The shell 1 is mainly made of plastic.

The plurality of absorbing parts are arranged along a straight line, the absorbing range of the absorbing parts is 0.5-10.00uL, and 12 absorbing parts are taken as an example in the figure. Specifically, the method comprises the following steps: the suction means includes a suction head connector 20, a suction pipe 21, and a driving block 22. Wherein:

the upper part of the sucker connecting piece 20 is positioned in the shell 1, the lower part of the sucker connecting piece 20 extends out of the bottom of the shell 1, the sucker connecting piece 20 is internally provided with a through hole, the upper part of the sucker connecting piece is connected with a liquid suction mechanism, and the lower part of the sucker connecting piece 20 is connected with a sucker 21. Preferably, the suction head connecting member 20 has a conical shape with a diameter gradually decreasing from top to bottom, so that the lower portion thereof is easily connected to the suction pipe 21. The suction head connecting piece 20 is made of metal, and can also be made of light stainless steel, strong hardness and corrosion resistance.

The pipette 21 is detachably attached to the lower portion of the pipette tip connector 20 and can be replaced as a consumable accessory after pipetting. The pipette 21 may be PPE with a range of 10uL commonly used in biochemical laboratories.

A drive block 22 is connected to the tip connector 20 for cooperation with the spacing adjustment mechanism. The driving block 22 is also made of light stainless steel.

The spacing adjusting mechanism is the invention of the application, and is connected with a plurality of suction parts and used for simultaneously adjusting the spacing between two adjacent suction parts, and the spacing adjusting range of the suction parts in the embodiment is-10.0-10.0 mm. The spacing adjustment mechanism in this embodiment mainly includes a driving rod 30, a threaded rod 31, and a transmission assembly. Specifically, the method comprises the following steps:

only one driving rod 30 can be arranged around the axis line of the driving rod 30 in a rotating mode, one end of the driving rod 30 is located in the shell 1 and is in transmission connection with the threaded rod 31 through the transmission assembly, so that the driving rod 30 rotates to drive the threaded rod 31 to rotate, and the other end of the driving rod 31 extends out of the top of the shell 1 to be used for rotating operation. The driving rod 30 is made of light stainless steel.

The threaded rod 31 is rotatably arranged in the shell 1 around the axis of the threaded rod 31, only one threaded rod is arranged, the extending direction of the threaded rod 31 is consistent with the arrangement direction of the plurality of suction components, the extending direction of the driving rod 30 is perpendicular to the extending direction of the threaded rod 31, the driving rod 30 is in transmission connection with the middle of the threaded rod 31, the thread turning directions of the two sides of the driving rod 30 on the threaded rod 31 are opposite, and the threaded rod 31 penetrates through the transmission block 22 of the suction component and is in thread fit with the transmission block 22, as shown in fig. 3. The threaded rod 31 is made of light stainless steel. In the figure, 12 suction parts, wherein 6 suction parts are connected on the threaded rod 31 positioned on one side, 6 suction parts are connected on the threaded rod 31 positioned on the other side, the distance between two adjacent suction parts is equal, the rotary driving rod 30 drives the threaded rod 31 to rotate, the suction parts are limited by the shell 1, the transmission block 22 is simultaneously used for moving towards the middle of the threaded rod 31 or towards two sides of the threaded rod 31, so that the adjustment of the distance between the suction parts is realized, if the suction parts move towards the middle of the threaded rod 31, the distance between two adjacent suction parts is reduced, if the suction parts move towards two sides of the threaded rod 31, the distance between two adjacent suction parts is reduced.

Drive assembly sets up in casing 1 for rotate the transmission with actuating lever 30 and drive threaded rod 31 and rotate for threaded rod 31, drive assembly's structure as long as can realize the mode of this effect all can, for example use a set of bevel gear, perhaps worm gear etc..

The distance adjusting mechanism can also be provided with an adjusting operation piece 32, an adjusting locking piece 33, a distance digital display module 34 and the like according to requirements.

Wherein:

the adjustment operation member 32 is attached to the drive lever 30 at a position protruding from the housing 1 for operating the drive lever 30 to rotate. If a knob is adopted, the drive rod 30 is driven to rotate by rotating the knob, and the phenomenon of loosening and sliding of the threads cannot occur at the joint of the adjusting operation piece 32 and the drive rod 30.

The adjustment lock 33 is used to lock the drive lever 30 in rotation, or to lock the adjustment operation member 32 against rotation. Thus, the driving rod 30 can be prevented from rotating to shift the spacing of the suction parts during operation, and the effect of fixing the spacing of the suction parts can be achieved. The adjusting and locking member 33 is not related to the invention of the present application, and is not necessarily structured as long as the desired effect can be achieved, and will not be described in detail herein.

The spacing digital display module 34 is used for displaying the spacing of the suction parts. The digital pitch display module 34 can display the pitch value of the suction component by using an electronic component, such as a sensor. When showing 00.0mm numerical value like interval digital display module 34, for absorbing part standard interval, the original point promptly, adjust operating parts 32 levogyration or dextrorotation accessible interval digital display module 34 and fix a position the interval fast, of course, in order to make things convenient for the use in the reality, can select when levogyration is adjusted operating parts 32, interval digital display module 34 numerical value shows red, when dextrorotation is adjusted operating parts 32, interval digital display module 34 numerical value shows black, be convenient for distinguish that the hole interval is that the equidistance reduces or the equidistance enlarges. The distance digital display module 34 is not related to the invention of the present application, and is not an essential structure as long as the required effect can be achieved, and will not be described in detail herein.

The liquid suction mechanism is connected with the plurality of suction components and is used for controlling the plurality of suction components to suck liquid or discharge liquid simultaneously. The liquid suction mechanism in this embodiment includes a pumping operation lever 40, a pumping unit 42, and a flexible connection tube 41. Wherein:

the pumping lever 40 is connected to the pumping unit 42 for actuating the pumping unit 42, one end of the pumping lever 40 is connected to the pumping unit 42, and the other end of the pumping lever 40 extends out of the top of the housing 1 and is provided with a ram 400 for operating the pumping lever 40. The pumping assembly 42 may be of conventional construction, such as a piston cylinder, piston combination, and the pumping lever 40 may be connected to a piston of the pumping assembly 42, or may correspond to a piston rod of the pumping assembly 42. The pumping unit 42 is not related to the invention of the present application as long as the desired effect is achieved, and will not be described in detail herein.

Since the pitch of the suction means is adjustable in this embodiment, the pumping unit 42 cannot be directly connected to the suction means. Thus, in this embodiment the pumping assembly 42 is sealingly connected to the suction head connector 20 of the suction unit by a plurality of flexible connecting tubes 41. Thus, even if the suction member is moved, the pumping unit 42 is not influenced to control the suction and discharge of the suction tube 21. The flexible connecting tube 41 is made of plastic material and has a certain flexibility, for example, a capillary tube can be used.

The distance adjusting mechanism can also be provided with a capacity digital display module 43 and the like according to needs. Wherein:

the volume display module 43 is used for displaying the liquid suction amount of the suction part. The digital volume display module 43 can use electronic components, such as sensors, to display the liquid absorption amount of the absorption components. The digital volume display module 43 can display a numerical value between 0.5 and 10.00, and the liquid suction amount of the suction part can be accurately controlled by setting the numerical value of the digital volume display module 43. The digital volume display module 43 is not related to the invention of the present application, and is not an essential structure as long as the required effect can be achieved, and will not be described in detail herein.

The following specifically describes the operation process of this embodiment:

in this embodiment, the operation hole pipette sucks 6uL of reaction product from a standard 96-well PCR plate and adds the reaction product to a small-pore 96-well agarose gel for electrophoresis, the distance between each suction component needs to be reduced, the adjustment operation member 32 on the multi-pore pipette is adjusted to a position displayed as 0.00mm (i.e. an original point) in the distance digital display module 34, which indicates that the state is a standard distance, the adjustment capacity digital display module 43 is displayed as 06.00uL, the housing 1 is held by hand, the pressure head 400 is operated, the suction force generated by the pumping assembly 42 accurately controls each suction head connecting piece 20 to be inserted into the suction tube 21 through the flexible connecting tube 41, the 6uL of reaction product is sucked from the standard 96-well PCR plate, and then the reaction product is transferred to a position right above the small-pore 96-pore agarose gel, the adjustment operation member 32 is rotated by the thumb to drive the driving rod 30 to rotate, the driving rod 31 is rotated by the driving assembly, the surface thread of the driving block 22 horizontally slides towards the middle of the threaded rod 31, the distance between the suction components is reduced, the PCR reaction product can be added to the agarose gel in the small-pore 96-pore agarose gel, the adjustment locking member 33 is locked, and the numerical value of the threaded rod 34 is recorded, so as to facilitate the rapid positioning in the same environment for many times.

The above embodiments are only for illustrating the technical concept and features of the present invention, and the purpose of the embodiments is to enable those skilled in the art to understand the contents of the present invention and implement the present invention, which cannot limit the protection scope of the present invention. All equivalent changes and modifications made according to the spirit of the present invention should be covered by the protection scope of the present invention.

Claims

1. A portable porous pipettor which characterized in that: the method comprises the following steps:

a housing;

a plurality of suction members arranged along a line;

spacing adjustment mechanism, spacing adjustment mechanism with a plurality of absorption part connect for adjust adjacent two absorption part between the interval, spacing adjustment mechanism include actuating lever, threaded rod and drive assembly, actuating lever, threaded rod all can set up around self axial lead with rotating, actuating lever one end with the threaded rod between pass through the drive assembly transmission connect and make the actuating lever rotate drive the threaded rod rotate, the extending direction of threaded rod with a plurality of the array orientation of absorption part unanimous, and the threaded rod on lie in the screw thread of actuating lever both sides revolve to opposite, absorption part with threaded connection between the threaded rod.

2. The portable porous pipette of claim 1, wherein: the threaded rod and the transmission assembly are arranged in the shell, and the other end of the driving rod extends out of the top of the shell for operation; the distance adjusting mechanism further comprises an adjusting operation piece and an adjusting locking piece, wherein the adjusting operation piece is connected to the position, extending out of the shell, of the driving rod and is used for operating the driving rod to rotate; the adjusting and locking piece is connected with the driving rod or the adjusting and operating piece and used for locking the driving rod in a rotating mode.

3. The portable porous pipette of claim 1, wherein: the distance adjusting mechanism further comprises a distance digital display module for displaying the distance between the suction parts.

4. The portable porous pipette of claim 1 or 3, characterized by: the distance adjusting range of the sucking components is-10.0-10.0 mm.

5. The portable porous pipette of claim 1, wherein: the sucking component comprises a sucking head connecting piece and a sucking pipe, wherein the upper part of the sucking head connecting piece is positioned in the shell and is connected with the liquid suction mechanism and the spacing adjusting mechanism; the lower part of the sucker connecting piece extends out of the bottom of the shell, and the sucker is detachably connected to the lower part of the sucker connecting piece.

6. The portable porous pipette of claim 5, wherein: the suction part also comprises a transmission block, the transmission block is connected on the suction head connecting piece, and the threaded rod passes through the transmission block and is in threaded fit with the transmission block.

7. The portable porous pipette of claim 5, wherein: the suction head connecting piece is in a conical shape with the diameter gradually reduced from top to bottom.

8. The portable porous pipette of claim 1, wherein: imbibition mechanism including pump the action bars, pump the subassembly and the flexonics pipe of pumping, pump the subassembly, the flexonics pipe setting is in the casing in, pump the one end of action bars and pump the subassembly and be connected and be used for the drive pump the subassembly action, pump the other end of action bars stretch out the casing top with the confession operation, pump the subassembly pass through the flexonics pipe with the part of absorbing connect.

9. The portable porous pipette of claim 1, wherein: the liquid suction mechanism comprises a capacity digital display module for displaying the liquid suction amount of the suction component.

10. The portable porous pipette of claim 1 or 9, wherein: the liquid absorption range of the absorption component is 0.5-10.00uL.